BE867702A - Nouveaux amino-acides fluores - Google Patents
Nouveaux amino-acides fluoresInfo
- Publication number
- BE867702A BE867702A BE188232A BE188232A BE867702A BE 867702 A BE867702 A BE 867702A BE 188232 A BE188232 A BE 188232A BE 188232 A BE188232 A BE 188232A BE 867702 A BE867702 A BE 867702A
- Authority
- BE
- Belgium
- Prior art keywords
- amino acids
- new fluorine
- fluorine amino
- new
- acids
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/802,391 US4325961A (en) | 1977-06-01 | 1977-06-01 | Fluorinated amino acids |
Publications (1)
Publication Number | Publication Date |
---|---|
BE867702A true BE867702A (fr) | 1978-12-01 |
Family
ID=25183569
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE188232A BE867702A (fr) | 1977-06-01 | 1978-06-01 | Nouveaux amino-acides fluores |
Country Status (4)
Country | Link |
---|---|
US (1) | US4325961A (fr) |
BE (1) | BE867702A (fr) |
PH (1) | PH16587A (fr) |
ZA (1) | ZA783121B (fr) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4431821A (en) * | 1977-06-01 | 1984-02-14 | Merck & Co., Inc. | Fluorinated tryptamines |
US4438270A (en) | 1977-07-11 | 1984-03-20 | Merrell Toraude Et Compagnie | α-Halomethyl derivatives of α-amino acids |
US5614557A (en) * | 1977-07-11 | 1997-03-25 | Marion Merrell Et Compagnie C/O Merrell Pharmaceuticals Inc. | Method of controlling tumor growth rate |
US4866206A (en) * | 1977-07-11 | 1989-09-12 | Merrell Dow France Et Cie | 2-Halomethyl derivatives of 2-amino acids |
US4413141A (en) * | 1977-07-11 | 1983-11-01 | Merrell Toraude Et Compagnie | 2-(Difluoromethyl)-2,5-diaminopentanoic acid |
US4560795A (en) * | 1979-04-10 | 1985-12-24 | Merrell Dow France et Cie. | α-Halomethyl derivatives of α-amino acids |
GB2083030B (en) * | 1980-08-23 | 1984-03-07 | Merrell Toraude & Co | Fluorinated pentene diamine derivatives |
US4447443A (en) * | 1982-11-15 | 1984-05-08 | Merck & Co., Inc. | Anti-inflammatory/analgesic combination of α-fluoromethylhistidine and a selected non-steroidal anti-inflammatory drug (NSAID) |
US4663347A (en) | 1983-10-31 | 1987-05-05 | Merck Frosst Canada, Inc. | Benzofuran 2-carboxylic acid esters useful as inhibitors of leukotriene biosynthesis |
US4522823A (en) * | 1984-01-05 | 1985-06-11 | Merck & Co., Inc. | Orexigenic use of α-fluoromethyl-histidine |
CA1309557C (fr) | 1985-06-18 | 1992-10-27 | Robert N. Young | Antagonistes de leucotrienes |
US4760091A (en) * | 1985-10-01 | 1988-07-26 | The Dow Chemical Company | Method of controlling phytopathogenic fungus |
US5196450A (en) * | 1985-12-19 | 1993-03-23 | Merrell Dow Pharmaceuticals Inc. | Method of inhibiting protozoal growth |
DE3786030T2 (de) | 1986-03-27 | 1993-12-02 | Merck Frosst Canada Inc | Tetrahydrocarbazole Ester. |
US5428033A (en) | 1990-10-12 | 1995-06-27 | Merck Frosst Canada, Inc. | Saturated hydroxyalkylquinoline acids as leukotriene antagonists |
US5030645A (en) * | 1990-10-15 | 1991-07-09 | Merck & Co., Inc. | Method of treating asthma using (S)-α-fluoromethyl-histidine and esters thereof |
US5410054A (en) * | 1993-07-20 | 1995-04-25 | Merck Frosst Canada, Inc. | Heteroaryl quinolines as inhibitors of leukotriene biosynthesis |
US5808146A (en) * | 1995-11-09 | 1998-09-15 | Emory University | Amino acid analogs for tumor imaging |
WO2002068592A2 (fr) * | 2001-02-27 | 2002-09-06 | Trustees Of Tufts College | Hexafluoreleucine non racemique, procedes d'elaboration et d'utilisation |
DE60333830D1 (de) * | 2002-04-30 | 2010-09-30 | Univ Emory | Verbindungen zur abbildung von tumoren |
US7837982B2 (en) * | 2005-06-23 | 2010-11-23 | Emory University | Imaging agents |
JP5349960B2 (ja) * | 2005-06-23 | 2013-11-20 | エモリー ユニバーシティー | 腫瘍画像化のためのアミノ酸類似体の立体選択的合成 |
US8246752B2 (en) | 2008-01-25 | 2012-08-21 | Clear Catheter Systems, Inc. | Methods and devices to clear obstructions from medical tubes |
CA3121513A1 (fr) * | 2018-12-06 | 2020-06-11 | Senda Biosciences, Inc. | Inhibiteurs de decarboxylase pour le traitement de la maladie de parkinson |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3046300A (en) * | 1960-10-21 | 1962-07-24 | Merck & Co Inc | alpha-trifluoromethyloxyphenylalanines |
US3395176A (en) * | 1964-03-06 | 1968-07-30 | Merck & Co Inc | Alpha-hydroxymethylphenylalanine compounds |
JPS5025465B1 (fr) * | 1970-12-29 | 1975-08-23 | ||
US4004996A (en) * | 1974-12-23 | 1977-01-25 | Merck & Co., Inc. | Fluorination of organic compounds |
-
1977
- 1977-06-01 US US05/802,391 patent/US4325961A/en not_active Expired - Lifetime
-
1978
- 1978-05-30 ZA ZA00783121A patent/ZA783121B/xx unknown
- 1978-06-01 BE BE188232A patent/BE867702A/fr not_active IP Right Cessation
- 1978-06-01 PH PH21222A patent/PH16587A/en unknown
Also Published As
Publication number | Publication date |
---|---|
PH16587A (en) | 1983-11-22 |
US4325961A (en) | 1982-04-20 |
ZA783121B (en) | 1979-07-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: MERCK & CO. INC. Effective date: 19870630 |