BE856412A - Procede de transformation de 2,7-dihydroxy-5-isopropylid7ne-2,6-methano-3,4,5,6-tetrahydro-2h-1-benzoxocine substituee en 9 en trans-1-hydroxy-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9h-dibenzo (b,d)pyran-9-one substituee en 3, - Google Patents

Procede de transformation de 2,7-dihydroxy-5-isopropylid7ne-2,6-methano-3,4,5,6-tetrahydro-2h-1-benzoxocine substituee en 9 en trans-1-hydroxy-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9h-dibenzo (b,d)pyran-9-one substituee en 3,

Info

Publication number
BE856412A
BE856412A BE1008246A BE1008246A BE856412A BE 856412 A BE856412 A BE 856412A BE 1008246 A BE1008246 A BE 1008246A BE 1008246 A BE1008246 A BE 1008246A BE 856412 A BE856412 A BE 856412A
Authority
BE
Belgium
Prior art keywords
substituted
benzoxocin
methano
dibenzo
hexahydro
Prior art date
Application number
BE1008246A
Other languages
English (en)
French (fr)
Inventor
W B Blanchard
Ch W Ryan
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BE856412A publication Critical patent/BE856412A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BE1008246A 1976-07-06 1977-07-04 Procede de transformation de 2,7-dihydroxy-5-isopropylid7ne-2,6-methano-3,4,5,6-tetrahydro-2h-1-benzoxocine substituee en 9 en trans-1-hydroxy-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9h-dibenzo (b,d)pyran-9-one substituee en 3, BE856412A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/702,808 US4054583A (en) 1976-07-06 1976-07-06 Process for converting 2,7-dihydroxy-5-isopropylidene-9-substituted-2,6-methano-3,4,5,6-tetrahydro-2H-1-benzoxocin to trans-1-hydroxy-3-substituted-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo(b,d)pyran-9-one

Publications (1)

Publication Number Publication Date
BE856412A true BE856412A (fr) 1978-01-04

Family

ID=24822688

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1008246A BE856412A (fr) 1976-07-06 1977-07-04 Procede de transformation de 2,7-dihydroxy-5-isopropylid7ne-2,6-methano-3,4,5,6-tetrahydro-2h-1-benzoxocine substituee en 9 en trans-1-hydroxy-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9h-dibenzo (b,d)pyran-9-one substituee en 3,

Country Status (11)

Country Link
US (1) US4054583A (de)
JP (1) JPS5943468B2 (de)
BE (1) BE856412A (de)
CA (1) CA1090358A (de)
CH (1) CH633788A5 (de)
DE (1) DE2729845C2 (de)
FR (1) FR2357557A1 (de)
GB (1) GB1584169A (de)
IE (1) IE45246B1 (de)
IL (1) IL52421A (de)
NL (1) NL7707466A (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1579137A (en) * 1976-07-06 1980-11-12 Lilly Co Eli 5-isopropylidene-2,6-methano-3,4,5,6-tetrahydro-2h-1-benzoxocins
US4395560A (en) * 1982-05-24 1983-07-26 Eli Lilly And Company Preparation of 6a,10a-trans-hexahydrodibenzopyranones
AU9102991A (en) * 1990-11-29 1992-06-25 Rhone-Poulenc Rorer International (Holdings) Inc. 2,6-methano-2h-1-benzoxocincarboxamides as 5-ht3-antagonists
US6566560B2 (en) 1999-03-22 2003-05-20 Immugen Pharmaceuticals, Inc. Resorcinolic compounds
WO2002026224A2 (en) * 2000-09-28 2002-04-04 Immugen Pharmaceuticals, Inc. Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation
WO2002026728A2 (en) * 2000-09-28 2002-04-04 Immugen Pharmaceuticals, Inc. Antiviral methods and compounds
CN1652766A (zh) * 2002-03-18 2005-08-10 免疫力药品有限公司 间苯二酚和大麻素的局部制剂及其施用方法
CA2638940C (en) * 2008-08-28 2009-09-15 Dalton Chemical Laboratories Inc. Improved synthesis of hexahydrodibenzopyranones

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2419936A (en) * 1942-04-29 1947-05-06 Adams Roger Preparation of compounds with marihuana activity
CH503724A (de) * 1966-05-13 1971-02-28 Hoffmann La Roche Verfahren zur Herstellung von polycyclischen Verbindungen
CH481911A (de) * 1967-05-19 1969-11-30 Theodor Dr Petrzilka Verfahren zur Herstellung von tricyclischen Verbindungen
US3700661A (en) * 1968-11-22 1972-10-24 Hoffmann La Roche Total steroid synthesis employing substituted isoxazole derivatives

Also Published As

Publication number Publication date
IE45246B1 (en) 1982-07-14
JPS5943468B2 (ja) 1984-10-22
IE45246L (en) 1978-01-06
IL52421A (en) 1980-09-16
FR2357557A1 (fr) 1978-02-03
FR2357557B1 (de) 1980-02-01
CH633788A5 (de) 1982-12-31
US4054583A (en) 1977-10-18
IL52421A0 (en) 1977-08-31
NL7707466A (nl) 1978-01-10
CA1090358A (en) 1980-11-25
DE2729845C2 (de) 1982-06-09
DE2729845A1 (de) 1978-01-19
GB1584169A (en) 1981-02-11
JPS537680A (en) 1978-01-24

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: ELI LILLY AND CY

Effective date: 19850731