BE841165A - 8-AZA-PROSTANOIC ACID DERIVATIVES AND THEIR PREPARATION PROCESS - Google Patents

8-AZA-PROSTANOIC ACID DERIVATIVES AND THEIR PREPARATION PROCESS

Info

Publication number
BE841165A
BE841165A BE166485A BE166485A BE841165A BE 841165 A BE841165 A BE 841165A BE 166485 A BE166485 A BE 166485A BE 166485 A BE166485 A BE 166485A BE 841165 A BE841165 A BE 841165A
Authority
BE
Belgium
Prior art keywords
aza
preparation process
acid derivatives
prostanoic acid
prostanoic
Prior art date
Application number
BE166485A
Other languages
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE841165A publication Critical patent/BE841165A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
BE166485A 1975-04-28 1976-04-27 8-AZA-PROSTANOIC ACID DERIVATIVES AND THEIR PREPARATION PROCESS BE841165A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57236675A 1975-04-28 1975-04-28

Publications (1)

Publication Number Publication Date
BE841165A true BE841165A (en) 1976-10-27

Family

ID=24287483

Family Applications (1)

Application Number Title Priority Date Filing Date
BE166485A BE841165A (en) 1975-04-28 1976-04-27 8-AZA-PROSTANOIC ACID DERIVATIVES AND THEIR PREPARATION PROCESS

Country Status (5)

Country Link
JP (1) JPS51143663A (en)
BE (1) BE841165A (en)
DE (1) DE2618341A1 (en)
FR (1) FR2309222A1 (en)
NL (1) NL7604330A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003007941A1 (en) * 2001-07-16 2003-01-30 F. Hoffmann-La Roche Ag 2 pyrrolidone derivatives as prostanoid agonists
WO2003074483A1 (en) 2002-03-05 2003-09-12 Ono Pharmaceutical Co., Ltd. 8-azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient
WO2004063158A1 (en) * 2003-01-10 2004-07-29 F.Hoffmann-La Roche Ag 2-piperidone derivatives as prostaglandin agonists
US6900336B2 (en) 2001-07-16 2005-05-31 Syntex (U.S.A.) Llc 8-aza-11-deoxy prostaglandin analogues
US7179820B2 (en) 2003-06-06 2007-02-20 Allergan, Inc. Piperidinyl prostaglandin E analogs
US7608637B2 (en) 2001-07-23 2009-10-27 Ono Pharmaceutical Co., Ltd. Pharmaceutical composition for treatment of diseases associated with decrease in bone mass comprising EP4 agonist as the active ingredient

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK5562003A3 (en) 2000-11-27 2004-08-03 Pfizer Prod Inc EP4 receptor selective agonists in the treatment of osteoporosis

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003007941A1 (en) * 2001-07-16 2003-01-30 F. Hoffmann-La Roche Ag 2 pyrrolidone derivatives as prostanoid agonists
US6849657B2 (en) 2001-07-16 2005-02-01 Syntex (U.S.A.) Llc 2-pyrrolidone derivatives as prostanoid agonists
US6900336B2 (en) 2001-07-16 2005-05-31 Syntex (U.S.A.) Llc 8-aza-11-deoxy prostaglandin analogues
CN100371322C (en) * 2001-07-16 2008-02-27 霍夫曼-拉罗奇有限公司 2-pyrrolidone derivatives as prostanoid agonists
US7608637B2 (en) 2001-07-23 2009-10-27 Ono Pharmaceutical Co., Ltd. Pharmaceutical composition for treatment of diseases associated with decrease in bone mass comprising EP4 agonist as the active ingredient
US8207223B2 (en) 2001-07-23 2012-06-26 Ono Pharmaceutical Co., Ltd. Pharmaceutical composition for treatment of diseases associated with decrease in bone mass comprising EP4 agonist as active ingredient
WO2003074483A1 (en) 2002-03-05 2003-09-12 Ono Pharmaceutical Co., Ltd. 8-azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient
WO2004063158A1 (en) * 2003-01-10 2004-07-29 F.Hoffmann-La Roche Ag 2-piperidone derivatives as prostaglandin agonists
US7271183B2 (en) 2003-01-10 2007-09-18 Roche Palo Alto Llc 2-Piperidone derivatives as prostaglandin agonists
US7179820B2 (en) 2003-06-06 2007-02-20 Allergan, Inc. Piperidinyl prostaglandin E analogs

Also Published As

Publication number Publication date
JPS51143663A (en) 1976-12-10
FR2309222A1 (en) 1976-11-26
DE2618341A1 (en) 1976-11-11
NL7604330A (en) 1976-11-01

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