BE835758A

BE835758A - MOLDED CONTAINER, CAPABLE OF CRASHING, INTENDED TO CONTAIN A SOLUTION

Info

Publication number: BE835758A
Application number: BE162025A
Authority: BE
Priority date: 1974-11-21
Filing date: 1975-11-20
Publication date: 1976-03-16
Also published as: ZA756968B

Description

       

  Récipient moulé, capable de s'écraser, àestiné à contenir une solution

  
 <EMI ID=1.1>  

  
 <EMI ID=2.1> 

  
Des récipients pour solution parentérale, en matière plastique souple , sent vendus actuellement par les

  
 <EMI ID=3.1> 

  
solution , lorsque celle-ci s'écoule.

  
Les sacs peur solutions parentérales dont on dispose à présent sont faits d'une paire de. feuilles pla-

  
 <EMI ID=4.1> 

  
matière plastique, scellés à chaud , par des récipients

  
 <EMI ID=5.1> 

  
ploi de ces récipients moulas par soufflage consiste dans

  
 <EMI ID=6.1> 

  
lène. 

  
La raison de est écrasement incomplet est que la

  
 <EMI ID=7.1> 

  
son écrasement complet.

  
;.il: autre inconvénient des récipients de solutions

  
 <EMI ID=8.1> 

  
Suivant l'invention, on procure un récipient pour solution parentérale , capable de s'écraser, qui peut être fait avantageusement d'une matière plastique plus raide,

  
 <EMI ID=9.1> 

  
vention s'écrase de manière uniforme , ce qui simplifie la détermination de la quantité de fluide qui reste dans le récipient à un instant quelconque. Pareillement, le

  
 <EMI ID=10.1> 

  
piration normale exercée par la tête d'aspiration de la solution de l'ensemble d'administration... 

  
Egalement, le récipient suivant l'invention peut être fabriqué de manière plus économique par le nouveau moule prévu suivant l'invention dans un processus de moulage par soufflage , que. les récipients pour solution ,

  
 <EMI ID=11.1> 

  
rieur. - 

  
Suivant l'invention , un récipient pour solution,

  
 <EMI ID=12.1> 

  
y 

  
d'une paraison de matière plastique , .tubulaire:. Le récipient comporte une partie de corps ayant une partie de col

  
 <EMI ID=13.1> 

  
trémités , et il est scellé à l'extrémité opposée- La partie de corps comporte, dans une configurât ion telle que moulée, une section transversale généralement ovale à proximité

  
de la partie du col et des épaules, cette section trans-

  
 <EMI ID=14.1> 

  
On préfère particulièrement, sans les récipients à solution capables d'être écrasés, suivant l'invention, que les circonférences des sections transversales représentées sur la. majeure partie de la longueur du récipient , soient essentiellement constantes , ce qui facilite un

  
 <EMI ID=15.1>  En outre, le récipient à solution suivant l'invention présente de préférence une paire de lignes longitudinales d'affaiblissement pour la flexion , définies,en disposition diamétralement opposée aux extrémités du grand. axe, des sections transversales ovales définies ci-dessus, pour faciliter encore l'écrasement à plat. ^gaiement, le plan'de l'extrémité opposée plate de ce récipient est généralement parallèle au grand axe des, sections transversales ovales du' récipient.

  
 <EMI ID=16.1> 

  
dans la partie du corps voisine de la partie des épaules.Les parties en goussets comprennent des lignes d'affaiblis-

  
 <EMI ID=17.1> 

  
à proximité de la partie des épaules lorsqu'on extrait le contenu du récipient, typiquement à travers la partie de col , alors que le récipient est disposé avec son col vers le bas. Dans ces- circonstances , les goussets- peuvent faciliter 1' écrasement aussi bien latéral que longitudinal du récipient que l'on vide.

  
Au surplus, on prévoit des lignes d'affaiblissement pour le pliage le long des bords opposés de la région des épaules pour faciliter 1* écrasement du récipient d'une

  
 <EMI ID=18.1> 

  
Le récipient à solution, capable de s'écraser , suivant l'invention, est constitué de matière plastique

  
 <EMI ID=19.1> 

  
 <EMI ID=20.1> 

  
les polyoléfines sont très peu coûteuses et présentent  beaucoup d'autres caractéristiques' souhaitables, telles que résistance , Température de ramollissement élevée (pour permettre le traitement à l'autoclave des récipients souples), et analogues. 

  
Sur les dessins, on a montré une forme de réalisation spécifique du récipient à solution suivait l'invention. Sur ces dessins :
- La figure 1 est une vue en perspective d'un réci- <EMI ID=21.1> 

  
 <EMI ID=22.1> 
- la figure 2 est une vue en élévation, inversée, <EMI ID=23.1> 

  
telle que roulée, placé dans le soûle utilisa pour le fabriquer, avec des parties du moule arrachées pour montrer

  
 <EMI ID=24.1> 
- la figure 5 est une vue en. plan du.récipient à  <EMI ID=25.1> 

  
et d'épaules de celui-ci ;  <EMI ID=26.1>  <EMI ID=27.1> 

  
que d'emploi ;
- la figure 5 est une vue en élévation, semblable <EMI ID=28.1>  <EMI ID=29.1>  qu'essentiellement tout le. contenu liquide ait été enlevé

  
 <EMI ID=30.1> 

  
du récipient s'écrase sous l'influence d'une aspiration normale d'une colonne de solution parentérale présente dans un ensemble d'administration attaché au récipient;  <EMI ID=31.1>  tion de la partie des épaules du récipient de la figure 6;
- la figure 7 est une vue en coupe considérée suivant la ligne 7-7 de la figure 2;  <EMI ID=32.1>  <EMI ID=33.1> 

  
du récipient de la figure 2 lorsqu'il est caris les conditions de la figure 5 ;
- la figure' 9 est une vue en élévation, fragmentaire, agrandie , considérée en section longitudinale, d'une par- <EMI ID=34.1>  montrant comment le moule suivant l'invention est utilise  dans une opération de moulage par soufflage pour fabriquer le récipient de la figure 2.

  
 <EMI ID=35.1> 

  
de préférence relativement raides , alors que le reste du

  
 <EMI ID=36.1> 

  
 <EMI ID=37.1> 

  
col et d'épaules 14, 16 , et comprend une partie aplatie

  
 <EMI ID=38.1> 

  
suspendre le récipient de la manière représentée à la <EMI ID=39.1>   <EMI ID=40.1> 

  
 <EMI ID=41.1> 

  
placée dans le bras du patient , pour permettre l'écoulement  d'unie solution parentérale du récipient 10 à une veine

  
 <EMI ID=42.1> 

  
30.

  
 <EMI ID=43.1> 

  
de façon à recevoir une partie en chapeau 32 qui peut être

  
 <EMI ID=44.1> 

  
 <EMI ID=45.1> 

  
des diaphragmes 35 qui s'étendent en travers des trous desdites lumières. Par suite, le récipient 10 s'ouvre à l'aide. d'une pointe stérile creuse de l'ensemble d'administration , qu'on y introduit en passant dans l'une des lumières d'accès 34 avant de rompre le diaphragme. On choisit les proportions de la pointe pour qu'elle assure un contact à glissement et étanche avec l'intérieur du passage 34, en sorte que la solution ne passe que par la pointe creuse et pénètre dans l'ensemble d'administration.
23.

  
 <EMI ID=46.1> 

  
un endroit d'injection en latex, pour l'administration.

  
- d'une médication, supplémentaire ou d'un autre produit à  ajouter au contenu du récipient -10^ <EMI ID=47.1>   <EMI ID=48.1>  soulage par soufflage que l'or, utilise peur fabriquer le

  
 <EMI ID=49.1> 

  
 <EMI ID=50.1> 

  
 <EMI ID=51.1> 

  
que l'on peut utiliser pour la fabrication, des récipients

  
 <EMI ID=52.1> 

  
un processus ce fabrication qui convient très bien pour les récipients suivant l'invention.

  
 <EMI ID=53.1> 

  
 <EMI ID=54.1> 

  
de moulage de col 48, 50 qui sont ensuite rapprochées par

  
 <EMI ID=55.1> 

  
le cours du processus et on introduit de l'air pour dilater la paraison chaude vers l'extérieur jusqu'à ce qu'elle  soit tendue de manière à s'adapter à la configuration de

  
 <EMI ID=56.1> 

  
refroidir. Après cela, on peut retirer le tube de soufflage
46 , ouvrir les moules et éjecter le récipient.

  
Une partie aplatie 20 est forcée par une extraite

  
 <EMI ID=57.1> 

  
Par suite, le récipient, souple suivant l'invention , sous forme telle que moulée, prend la forme nouvelle de

  
la cavité du moule montrée ici aux figures 2 et 10,laquelle forme est représentée plus complètement aux figures 3, 4,  <EMI ID=58.1> 

  
 <EMI ID=59.1> 

  
guration roulée montrée aux figures précédentes, est retiré. 

  
Suivait l'invention, le récipient: pour solution,

  
 <EMI ID=60.1> 

  
distance que l'on peut choisir s'étendant sur une partie du récipient à parois parallèles 53 qui s'étend de préférence sur moins que la moitié de la longueur du récipient, en sorte que la partie 49 constitue une partie principale du récipient.

  
Le but de la partie rétrécie 49 est de faciliter une manière uniforme d'écrasement à plat au récipient, pro-

  
 <EMI ID=61.1> 

  
gressivement aux figures 4, 5 et 6.

  
Le récipient suivant l'invention s'écrase ainsi

  
 <EMI ID=62.1>   <EMI ID=63.1> 

  
 <EMI ID=64.1> 

  
la forme du sac de la figure - est idéalisée en ce sens que la for&#65533;e spécifique montrée représente le sac tel que moule , des fins d'illustration. Un fait, la

  
 <EMI ID=65.1> 

  
 <EMI ID=66.1> 

  
Gent légèrement sur la plus grande partie de leur longueur

  
 <EMI ID=67.1> 

  
 <EMI ID=68.1> 

  
du récipient, que les pourtours de toutes les sections transversales perpendiculaires à l'axe soient essentiellenient constants.

  
 <EMI ID=69.1> 

  
 <EMI ID=70.1> 

  
 <EMI ID=71.1> 

  
 <EMI ID=72.1> 

  
forme. 

  
La paroi épaisse des récipients de polypropylene suivant l'invention est d'une épaisseur qui varie de pré-

  
 <EMI ID=73.1> 

  
préférable que l'épaisseur de paroi . à l'extrémité 18 soit

  
 <EMI ID=74.1> 

  
s'accroît progressivement jusqu'à atteindre un maximum de 0,50 mm dans la région de la partie d'épaules 16.

  
 <EMI ID=75.1> 

  
faiblissement 58 pour favoriser la flexion sont définies

  
 <EMI ID=76.1> 

  
ter encore l'écrasement à plat du récipient 10. Une vue en coupe- détaillée de la ligne d'affaiblissement 58 pour

  
 <EMI ID=77.1> 

  
Une paraison tubulaire, en se dilatant, 36, vient en contact avec les parois des, moitiés de moules 38, 40 et tend

  
à se refroidir rapidement et à durcir.La paraison en voie de dilatation rencontre d'abord des moitiés de moules 38, 40 dans les régions 60 et 62 , et dans ces régions la paraison durcit rapidement et devient immobile. Cependant, les moi-

  
 <EMI ID=78.1> 

  
qué. Finalement, la paraison remplit la région découpée 
63, 64 , mais ici, sa dilatation a formé une. partie liné- 

  
 <EMI ID=79.1> 

  
 <EMI ID=80.1> 

  
 <EMI ID=81.1> 

  
 <EMI ID=82.1>  

  
ou circulaire. Le rayon 65 de la section transversale en

  
 <EMI ID=83.1> 

  
 <EMI ID=84.1> 

  
est de préférence parallèle au grand axe 66 de la région ovale des gaules 16, comme montré à la figure 3. Ceci aussi facilite un écrasement à plat, uniforme.

  
 <EMI ID=85.1> 

  
 <EMI ID=86.1> 

  
et sont disposées en retrait par rapport à elles, en sorte que les pointes 70 des épaules s'avancent vers l'extérieur :  à partir des parties en goussets. Chaque partie en gousset

  
 <EMI ID=87.1> 

  
chacune présente des lignes d'affaiblissement, favorables à la flexion, qui peuvent avoir une structure semblable à celle des lignes d'affaiblissement pour la flexion, 58.

  
 <EMI ID=88.1> 

  
térieur du sac, tandis que les lignes 74 et 76 peuvent être des lignes d'affaiblissement ayant une structure de

  
 <EMI ID=89.1> 

  
térieur, semblable à celle que montre la figure 7. Des lignes d'affaiblissement 72, 74, 76 peuvent être formées par des rainures appropriées dans les moitiés de moule

  
 <EMI ID=90.1> 

  
dans la moitié de coule pour former la ligne d'affaiblissement favorable à la flexion. Toutes les lignes d'affaiblissement favorables à la flexion, 58, 72, 74 et 76 peuvent être simplement des lignes de plissement moulées

  
 <EMI ID=91.1> 

  
appropriées existant dans la moule. Toute ligne de plis-sement convenable qui permet une variation angulaire entre les parties des parois du sac peut être utilisée dans la présente invention. 

  
La structure des goussets permet un écrasement supplémentaire sous l'effet de la pression d'aspiration nor-

  
 <EMI ID=92.1> 

  
 <EMI ID=93.1> 

  
l'élévation normale du récipient lors de l'emploi. Le <EMI ID=94.1> 
16, ce qui réduit encore le volume du récipient écrasé , et ce qui germez l'expulsion de plus de solution parentéraie. Ceci est représenté plus particulièrement par les  figures 6A et 9 lorsqu'on les compare aux figures 5 et 8.

  
Les bords latéraux de la partie des épaules 16 constituent chaque fois une ligne transversale d'affaiblissement 81 pour le pliage , qui facilite 1' écrasement du récipient suivant l'invention, cosse représenté parti--

  
 <EMI ID=95.1> 

  
permettent à l'air de s'échapper des rainures formées dans les moitiés de soûles pour définir différentes lignes 

  
 <EMI ID=96.1> 

  
de la paroi du récipient peuvent se dilater plus complète-

  
 <EMI ID=97.1>   <EMI ID=98.1> 

  
mentaire- favorisant la flexion, que l'on peut utiliser pour
-faciliter 1'Ecrasement vers l'intérieur des parois du sac à proximité, de la partie des épaules 16, comme représenté <EMI ID=99.1> 

  
façon représentée à la figure 7, ou de toute autre,manière souhaitable.. 

  
Le récipient souple suivant l'invention peut être moulé,. facilement , ,'rempli aisément de solution parentérale ou d'un autre produit quelconque voulu et stérilisé si nécessaire par passage à l'autoclave, en'particulier lorsque le récipient suivant l'invention est constitué d'une matie-  re plastique à point de fusion élevé, telle que le polypropylène. Lorsque le contenu est vidé du récipient retour-

  
 <EMI ID=100.1> 

  
mettre une mesure précise de la quantité de solution extraite du récipient , bien que le récipient contienne moins d'air résiduel que ce n'était nécessaire précédemment pour  lire facilement la quantité de liquide débitée.

  
La description qui a été donnée ci-dessus n'est que représentative et ne tend pas à limiter l'invention. 

  
 <EMI ID=101.1> 

  
à contenir une solution, fait d'une parais on ce matière  plastique tubulaire, comportant une partie de corps qui a une partie de col faisant corps avec le récipient, et une partie formant épaules à une de ses extrémités et

  
 <EMI ID=102.1> 

  
avec le perfectionnement consistant en ce que la partie de corps présente, telle que moulée, une section transversale  généralement ovale près des parties de col et des épaules, cette section transversale s'amenuisant pour réaliser une

  
 <EMI ID=103.1> 

  
mité envisagée précédemment , pour faciliter une façon de s'écraser à plat du récipient, de façon progressive depuis l'extrémité opposée jusqu'à l'extrémité envisagée

  
 <EMI ID=104.1> 

  
 <EMI ID=105.1> 

  
avec cette partie de col dirigée vers le bas.

  
 <EMI ID=106.1> 



  Molded container, capable of collapsing, intended to contain a solution

  
 <EMI ID = 1.1>

  
 <EMI ID = 2.1>

  
Containers for parenteral solution, made of flexible plastic material, are currently sold by

  
 <EMI ID = 3.1>

  
solution, when it flows.

  
The parenteral solution bags now available are made from a pair of. flat sheets

  
 <EMI ID = 4.1>

  
plastic, heat-sealed, in containers

  
 <EMI ID = 5.1>

  
The use of these blow molded containers consists of

  
 <EMI ID = 6.1>

  
lene.

  
The reason for this incomplete overwriting is that the

  
 <EMI ID = 7.1>

  
its complete crushing.

  
; .il: another drawback of solution containers

  
 <EMI ID = 8.1>

  
According to the invention, there is provided a container for parenteral solution, capable of collapsing, which can advantageously be made of a stiffer plastic material,

  
 <EMI ID = 9.1>

  
The invention is uniformly crushed, making it easier to determine how much fluid is left in the container at any one time. Likewise, the

  
 <EMI ID = 10.1>

  
normal piration exerted by the solution suction head of the administration set ...

  
Also, the container according to the invention can be manufactured more economically by the new mold provided according to the invention in a blow molding process, than. containers for solution,

  
 <EMI ID = 11.1>

  
laughing. -

  
According to the invention, a container for solution,

  
 <EMI ID = 12.1>

  
y

  
a parison of plastic, .tubular :. The container has a body portion having a neck portion

  
 <EMI ID = 13.1>

  
hoppers, and it is sealed at the opposite end - The body portion has, in such a molded configuration, a generally oval cross section nearby

  
of the part of the neck and shoulders, this section trans-

  
 <EMI ID = 14.1>

  
Particularly preferred, without the collapsible solution vessels according to the invention, is that the circumferences of the cross sections shown in the. most of the length of the container, are essentially constant, which facilitates

  
 <EMI ID = 15.1> Further, the solution container according to the invention preferably has a pair of defined longitudinal flexural weakening lines in diametrically opposed arrangement at the ends of the large. axis, oval cross sections defined above, to further facilitate flat crushing. Cheerfully, the plane of the flat opposite end of this container is generally parallel to the major axis of the oval cross sections of the container.

  
 <EMI ID = 16.1>

  
in the part of the body adjoining the part of the shoulders The gusseted parts include lines of weakness

  
 <EMI ID = 17.1>

  
near the shoulder portion when extracting the contents of the container, typically through the neck portion, while the container is disposed with its neck down. Under these circumstances, the gussets may facilitate both lateral and longitudinal crushing of the container being emptied.

  
In addition, lines of weakness for the folding are provided along the opposite edges of the shoulder region to facilitate the collapsing of the container with a minimum.

  
 <EMI ID = 18.1>

  
The solution container, capable of collapsing, according to the invention, is made of plastic material

  
 <EMI ID = 19.1>

  
 <EMI ID = 20.1>

  
polyolefins are very inexpensive and have many other desirable characteristics, such as strength, high softening temperature (to allow autoclaving of flexible containers), and the like.

  
In the drawings, there is shown a specific embodiment of the solution container according to the invention. On these drawings:
- Figure 1 is a perspective view of a reci- <EMI ID = 21.1>

  
 <EMI ID = 22.1>
- figure 2 is an elevational view, inverted, <EMI ID = 23.1>

  
as rolled, placed in the base used to make it, with parts of the mold torn off to show

  
 <EMI ID = 24.1>
- Figure 5 is a view in. receptacle plan at <EMI ID = 25.1>

  
and shoulders of it; <EMI ID = 26.1> <EMI ID = 27.1>

  
than employment;
- Figure 5 is an elevational view, similar <EMI ID = 28.1> <EMI ID = 29.1> as essentially all. liquid content has been removed

  
 <EMI ID = 30.1>

  
the container collapses under the influence of normal suction from a column of parenteral solution present in an administration set attached to the container; <EMI ID = 31.1> tion of the shoulder part of the container in Figure 6;
- Figure 7 is a sectional view taken along line 7-7 of Figure 2; <EMI ID = 32.1> <EMI ID = 33.1>

  
of the container of Figure 2 when it meets the conditions of Figure 5;
- Figure 9 is an elevational view, fragmentary, enlarged, viewed in longitudinal section, of a par- <EMI ID = 34.1> showing how the mold according to the invention is used in a blow molding operation to manufacture the container of figure 2.

  
 <EMI ID = 35.1>

  
preferably relatively steep, while the rest of the

  
 <EMI ID = 36.1>

  
 <EMI ID = 37.1>

  
collar and shoulders 14, 16, and includes a flattened part

  
 <EMI ID = 38.1>

  
suspend the container as shown in <EMI ID = 39.1> <EMI ID = 40.1>

  
 <EMI ID = 41.1>

  
placed in the patient's arm, to allow the flow of a parenteral solution from the container 10 to a vein

  
 <EMI ID = 42.1>

  
30.

  
 <EMI ID = 43.1>

  
so as to receive a cap portion 32 which can be

  
 <EMI ID = 44.1>

  
 <EMI ID = 45.1>

  
diaphragms 35 which extend across the holes of said lumens. As a result, the container 10 opens for help. a hollow sterile tip of the administration set, which is introduced by passing through one of the access lumens 34 before breaking the diaphragm. The proportions of the tip are chosen so that it provides sliding and sealed contact with the interior of passage 34, so that the solution only passes through the hollow tip and enters the administration set.
23.

  
 <EMI ID = 46.1>

  
a latex injection site, for administration.

  
- a medication, supplement or other product to be added to the contents of the container -10 ^ <EMI ID = 47.1> <EMI ID = 48.1> relieves by blowing that gold, uses to make the

  
 <EMI ID = 49.1>

  
 <EMI ID = 50.1>

  
 <EMI ID = 51.1>

  
that can be used in the manufacture of containers

  
 <EMI ID = 52.1>

  
a manufacturing process which is very suitable for the containers according to the invention.

  
 <EMI ID = 53.1>

  
 <EMI ID = 54.1>

  
neck molding 48, 50 which are then brought together by

  
 <EMI ID = 55.1>

  
during the process and air is introduced to expand the hot parison outward until it is stretched to accommodate the configuration of

  
 <EMI ID = 56.1>

  
cool. After that we can remove the blowing tube
46, open the molds and eject the container.

  
A flattened part 20 is forced by an extracted

  
 <EMI ID = 57.1>

  
As a result, the flexible container according to the invention, in molded form, takes the new form of

  
the mold cavity shown here in Figures 2 and 10, which shape is shown more fully in Figures 3, 4, <EMI ID = 58.1>

  
 <EMI ID = 59.1>

  
rolled guration shown in the previous figures, is removed.

  
The invention followed the container: for solution,

  
 <EMI ID = 60.1>

  
a selectable distance extending over a portion of the parallel-walled container 53 which preferably extends less than half the length of the container, such that portion 49 constitutes a main part of the container.

  
The purpose of the constricted portion 49 is to facilitate a uniform manner of crushing flat to the container, pro-

  
 <EMI ID = 61.1>

  
gradually to figures 4, 5 and 6.

  
The container according to the invention thus crashes

  
 <EMI ID = 62.1> <EMI ID = 63.1>

  
 <EMI ID = 64.1>

  
bag shape in figure - is idealized in that the specific drill shown represents the bag as a mold, for illustrative purposes. A fact, the

  
 <EMI ID = 65.1>

  
 <EMI ID = 66.1>

  
Gent lightly for most of their length

  
 <EMI ID = 67.1>

  
 <EMI ID = 68.1>

  
of the container, that the peripheries of all the cross sections perpendicular to the axis are essentially constant.

  
 <EMI ID = 69.1>

  
 <EMI ID = 70.1>

  
 <EMI ID = 71.1>

  
 <EMI ID = 72.1>

  
form.

  
The thick wall of polypropylene containers according to the invention is of a thickness which varies from pre-

  
 <EMI ID = 73.1>

  
better than the wall thickness. at end 18 is

  
 <EMI ID = 74.1>

  
gradually increases to a maximum of 0.50 mm in the region of the shoulder part 16.

  
 <EMI ID = 75.1>

  
weakening 58 to promote flexion are defined

  
 <EMI ID = 76.1>

  
again the flat crushing of the container 10. A detailed sectional view of the line of weakness 58 for

  
 <EMI ID = 77.1>

  
An expanding tubular parison 36 comes into contact with the walls of the mold halves 38, 40 and stretches

  
to cool rapidly and harden. The expanding parison first encounters mold halves 38, 40 in regions 60 and 62, and in these regions the parison quickly hardens and becomes immobile. However, the me-

  
 <EMI ID = 78.1>

  
than. Finally, the parison fills the cut region
63, 64, but here its dilation formed a. linear part

  
 <EMI ID = 79.1>

  
 <EMI ID = 80.1>

  
 <EMI ID = 81.1>

  
 <EMI ID = 82.1>

  
or circular. The radius 65 of the cross section in

  
 <EMI ID = 83.1>

  
 <EMI ID = 84.1>

  
is preferably parallel to the major axis 66 of the oval region of the saplings 16, as shown in Figure 3. This too facilitates a flat, uniform crush.

  
 <EMI ID = 85.1>

  
 <EMI ID = 86.1>

  
and are set back with respect to them, so that the points 70 of the shoulders project outwards: from the gusseted parts. Each part in gusset

  
 <EMI ID = 87.1>

  
each has lines of weakness, favorable to bending, which may have a structure similar to that of lines of weakness for bending, 58.

  
 <EMI ID = 88.1>

  
sack, while lines 74 and 76 may be lines of weakness having a structure of

  
 <EMI ID = 89.1>

  
lower, similar to that shown in Figure 7. Lines of weakness 72, 74, 76 may be formed by suitable grooves in the mold halves.

  
 <EMI ID = 90.1>

  
in the sinking half to form the weakening line favorable to bending. All deflection-friendly lines of weakness, 58, 72, 74, and 76 can be simply molded crease lines

  
 <EMI ID = 91.1>

  
appropriate existing in the mold. Any suitable crease line which allows for angular variation between the wall portions of the bag can be used in the present invention.

  
The structure of the gussets allows additional crushing under the effect of the normal suction pressure.

  
 <EMI ID = 92.1>

  
 <EMI ID = 93.1>

  
the normal elevation of the container during use. The <EMI ID = 94.1>
16, which further reduces the volume of the crushed container, and which germinates the expulsion of more parenteral solution. This is shown more particularly by Figures 6A and 9 when compared to Figures 5 and 8.

  
The side edges of the shoulder portion 16 each constitute a transverse line of weakness 81 for the folding, which facilitates the crushing of the container according to the invention, thimble shown as part--

  
 <EMI ID = 95.1>

  
allow air to escape from the grooves formed in the socket halves to define different lines

  
 <EMI ID = 96.1>

  
wall of the container may expand more fully

  
 <EMI ID = 97.1> <EMI ID = 98.1>

  
mentally- promoting flexion, which can be used for
-facilitate the inward crushing of the walls of the bag near the shoulder part 16, as shown <EMI ID = 99.1>

  
as shown in Figure 7, or any other desirable manner.

  
The flexible container according to the invention can be molded ,. easily,, easily filled with parenteral solution or any other desired product and sterilized if necessary by autoclaving, in particular when the container according to the invention is made of a point-of-use plastic material. high melting, such as polypropylene. When the contents are emptied from the return container -

  
 <EMI ID = 100.1>

  
take an accurate measurement of the amount of solution withdrawn from the container, although the container contains less residual air than was previously necessary to easily read the amount of liquid delivered.

  
The description which has been given above is only representative and does not tend to limit the invention.

  
 <EMI ID = 101.1>

  
to contain a solution, made of a tubular plastics material, comprising a body part which has a neck part integral with the container, and a shoulder part at one end thereof and

  
 <EMI ID = 102.1>

  
with the improvement that the body portion has, as molded, a generally oval cross section near the neck and shoulder portions, which cross section tapers to provide a

  
 <EMI ID = 103.1>

  
mite previously envisaged, to facilitate a way of collapsing the container flat, progressively from the opposite end to the envisaged end

  
 <EMI ID = 104.1>

  
 <EMI ID = 105.1>

  
with this part of the neck facing downwards.

  
 <EMI ID = 106.1>

Claims

Holding a solution as claimed in claim 1 wherein along a major portion of the length of the container the peripheries of all cross sections are substantially constant to facilitate flat crushing.

3. A container capable of collapsing, intended to contain a solution, according to claim 2, characterized in that a pair of longitudinal weakening lines, favorable to bending, are made in diametrically opposed arrangement, to facilitate the 'crushing

flat. 4. Container capable of collapsing, intended to contain a solutior :, according to claim 3, characterized in that a part of the container, adjacent to said end considered first, is of generally oval, regular cross section, and in that the major part of the container, closer to the opposite end, tapers, gradually to a configuration <EMI ID = 107.1>

flat tie of the opposite extract being generally parallel to the major axis of the oval cross section.

5.- A container capable of collapsing, intended to contain a solution, according to claim 4, characterized in that it is made of a film of polypro-

6.-; .Ioule for the manufacture of a container capable of collapsing, intended to contain a solution, made of a parison of tubular plastic material, this mold

mold to define a container body portion having a shoulder portion at one end thereof, with the mold portion sinking chamber for the body portion shaped to define a generally oval-shaped cross section near the neck portions and shoulders, this cross section of the chamber forming the body part tapering to a flat configuration at the end of the container opposite said first end, to mold a collapsible container which exhibits a collapsible mode. 'essentially flat crushing

to the end mentioned first, when the contents of the container are removed; by the shoulder part, when the container is placed with the shoulder part

additional rolling means this the neck part, close to the means which force the shoulder part.

in that all of the cross sections along a major portion of the body ci-tree have for-courses which are essentially constant, to facilitate flattening of the flexible containers which are soldered in this socket.

in that the chancre part which forces the body has a pair of longitudinal grooves arranged opposite each other to define longitudinal lines

in that the part of the chamber which- forms the body near the shoulder-straining parts is of generally oval, uniform cross-section, while a major part of this chamber part, closest to the extremity opposite, gradually decreases to

the plane of the flat part of the opposite end being generally parallel to the major axis of the trans- section

a relatively stiff shoulder portion at one of its ends, the container being sealed at its end

according to claim 11, wherein each gusset portion has a recessed portion proximate to

14.- A container for containing a solution, according to claim 15, characterized in that each

and triangular in shape, one of the sides defining the transverse line of weakness for bending, and

<EMI ID = 127.1> weakening favorable to bending ,, to facilitate

15.- Molded receptacle, capable of collapsing, intended to contain a solution, - this receptacle comprising a body part having a part forming a neck which is integral with it and a part forming shoulders at one of its ends , and sealed at its end- opposite to the first,

The body has, in its as-molded form, a generally oval cross section near the neck and shoulder portions, the cross section tapering to a flat shape at the end of the container opposite the first end, to facilitate a substantially uniform flat crushing of the container, gradually from the opposite end to the first * end when extracting the contents of <EMI ID = 130.1>

pient is placed with this part of the neck facing

the bottom, the container also having gusseted parts in the body part near the shoulder part, these gusseted parts having weak lines favorable to bending, to facilitate the collapsing of the container close to the shoulder part when extracting its contents.

16. A container for containing a solution, according to claim 15, characterized in that a pair of gusset-forming parts are placed in diametrically opposed arrangement on the major axis of the generally oval cross section, near the portion of shoulders. 17.- A container for receiving a solution, according to claim 16 ,. characterized in that each gusset part has a recessed part nearby

of the shoulder part, each gusset part presenting

. also a weakening line favorable to bending <EMI ID = 131.1>

deflection favorable to bending being placed transversely to the axis of the container, to bend during

of its axial crushing .'--- '

18.- A container for receiving a solution, according to claim 17, characterized in that each '

triangular shape, one of the sides representing the transverse line of weakening favorable to bending,

and the other two sides also representing lines of weakness favorable to bending to facilitate crushing of the walls of the bag near the shoulder portion.

19.-. Container capable of crashing, intended for. contain a solution according to claim 18, characterized in that it is made of a film of polypro-

20. A collapsible container for containing a solution, according to claim 18, still having transverse lines of weakness favorable to bending, spaced from the edges of the shoulder portions, to facilitate lateral and longitudinal crushing. of the container when emptying it.

<EMI ID = 135.1> terized in that it presents a line of weakness

22.- Container capable of collapsing, intended for

both lines of weakness favorable to folding, arranged transversely, defined along opposing edges

of the container.

23.- In a mold, for a receptacle capable of collapsing and intended to contain a solution, made of a paraisoh of tubular plastic material, which flows

part which forms the body of the container, this mold also had a part forming a neck and a part

proximity to the part which forms the shoulders, the part which the gussets presenting means to force

blow-molded containers formed by said mold to facilitate crushing of the containers when their contents are extracted therefrom.

24.- � oule according to claim 23, characterized

- in that the means for forming the lines of weakness- <EMI ID = 142.1>

of the mold which have the channels forming an angular edge with the rest of the wall of the mold to touch and retain the plastic walls of the container; which expand during blow molding, and to allow a linear portion of the container wall

of plastic material to expand further as it enters the channels, to achieve a curved cross section and reduced thickness, and therefore a collapse.

in that a linear rib is produced in the part forming the gussets, arranged transversely with respect to the axis of the mold.

26. A koule according to claim 25, wherein a pair of longitudinal channels emerge defined in the

for facilitating the formation of longitudinal weakening lines favorable to bending, for flat crushing in plastic containers intended

terized in that the flow chamber has a portion of generally oval cross section nearby.

of the part forming the shoulders, the cross section of the chamber gradually tapering off to achieve a flat configuration of the end of the neck, opposite said first end, to facilitate crushing

its opposite end to the first end, when gold. extracts the contents of the container through the part

down. <EMI ID = 150.1>

the two parts which form the gussets are placed,

of the long axis of the generally oval cross section.

29.- 1-mold according to claim 28, wherein each portion which forms a gusset has a portion which protrudes into the chamber, forced by the mold halves, and has means for closing lines of weakness favorable to flexion in each gusset, lines which are placed transversely to the axis of the mold.

-'risé in that each part forming a gusset is essentially three-sided and triangular in shape, one of the sides having means for forming the transverse line of weakening favorable to bending, and the other two remaining sides also having means for forming lines of weakness favorable to bending.

containing a solution, which has a body part having an integral neck part and a semi-rigid shoulder part at one end thereof, and which is sealed at its end opposite to said end , the improvement in that transverse lines of weakening favorable to folding are provided along opposite edges of the shoulder portion to facilitate crushing of the container.

32.- Container capable of collapsing, intended for

still taking parts forming gussets, made in

Blend favorable to folding, the parities forming gussets comprising lines of weakness favorable to bending, to facilitate crushing of the container near the shoulder portion, when its contents are removed.

lene.

containing a solution, according to claim 32, wherein the body part has, when molded, a cross-section, generally: oval, to

transverse tapering to a flat configuration at the opposite end of the first end, to facilitate substantially uniform flat crushing of the container, gradually from that opposite end to the first end, as it is pulled out the contents through the neck portion, when the container is disposed with the neck down.

35.- Container intended to contain a solution,

gusset part comprises a. part hollowed out near the shoulder part ,. each gusset also exhibiting a line of weakness favorable to bending - <EMI ID = 163.1>

-axial crushing of the container.

36.- In a mold for a container capable of crushing

make a part closing the container body, the = oule

means for sealing the container the end of the mold opposite said first end, the improvement comprising means for forcing transverse lines of weakness favorable to folding, along the edges

drilled in the mold, to facilitate the crushing of the container formed in the mold.

vent means are provided in conjunction with the means for forming transverse lines of weakness favorable to folding, to prevent the entrapment of air in the means which force said line of weakness.