BE806466A - 1-(betachloroethyl)-3-(oxo-alkyleneimino)-1-nitroso-ureas - anti-leukaemia and anti-tumour agents - Google Patents
1-(betachloroethyl)-3-(oxo-alkyleneimino)-1-nitroso-ureas - anti-leukaemia and anti-tumour agentsInfo
- Publication number
- BE806466A BE806466A BE137025A BE137025A BE806466A BE 806466 A BE806466 A BE 806466A BE 137025 A BE137025 A BE 137025A BE 137025 A BE137025 A BE 137025A BE 806466 A BE806466 A BE 806466A
- Authority
- BE
- Belgium
- Prior art keywords
- oxo
- betachloroethyl
- alkyleneimino
- leukaemia
- nitroso
- Prior art date
Links
- 230000000259 anti-tumor effect Effects 0.000 title 1
- 229940045719 antineoplastic alkylating agent nitrosoureas Drugs 0.000 title 1
- 208000032839 leukemia Diseases 0.000 title 1
- LPXPTNMVRIOKMN-UHFFFAOYSA-M sodium nitrite Chemical compound [Na+].[O-]N=O LPXPTNMVRIOKMN-UHFFFAOYSA-M 0.000 abstract 2
- QFHSKSYERHONFB-UHFFFAOYSA-N 1-(2-chloroethyl)-3-(2-oxopiperidin-3-yl)urea Chemical compound ClCCNC(=O)NC1C(NCCC1)=O QFHSKSYERHONFB-UHFFFAOYSA-N 0.000 abstract 1
- BDAGIHXWWSANSR-UHFFFAOYSA-N Formic acid Chemical compound OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000004202 carbamide Substances 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 235000019253 formic acid Nutrition 0.000 abstract 1
- 235000010288 sodium nitrite Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
- C07C273/1854—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas by reactions not involving the formation of the N-C(O)-N- moiety
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10829672A JPS4966688A (is") | 1972-10-28 | 1972-10-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE806466A true BE806466A (en) | 1974-02-15 |
Family
ID=14481073
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE137025A BE806466A (en) | 1972-10-28 | 1973-10-24 | 1-(betachloroethyl)-3-(oxo-alkyleneimino)-1-nitroso-ureas - anti-leukaemia and anti-tumour agents |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JPS4966688A (is") |
| BE (1) | BE806466A (is") |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5136477A (en) * | 1974-09-20 | 1976-03-27 | Toray Industries | Arufua amino ipushiron kapurorakutamu no tanriho |
-
1972
- 1972-10-28 JP JP10829672A patent/JPS4966688A/ja active Pending
-
1973
- 1973-10-24 BE BE137025A patent/BE806466A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS4966688A (is") | 1974-06-27 |
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