BE802709A - Nouveau produit actif pour le traitement de la leucemie a base d'acide n5 methiltetrahydrohomofulique ou des derives - Google Patents

Nouveau produit actif pour le traitement de la leucemie a base d'acide n5 methiltetrahydrohomofulique ou des derives

Info

Publication number
BE802709A
BE802709A BE133796A BE133796A BE802709A BE 802709 A BE802709 A BE 802709A BE 133796 A BE133796 A BE 133796A BE 133796 A BE133796 A BE 133796A BE 802709 A BE802709 A BE 802709A
Authority
BE
Belgium
Prior art keywords
methiltetrahydrohomofulic
derivatives
acid
treatment
new active
Prior art date
Application number
BE133796A
Other languages
English (en)
French (fr)
Inventor
J A R Mead
Original Assignee
Us Gov Health & Human Serv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv filed Critical Us Gov Health & Human Serv
Publication of BE802709A publication Critical patent/BE802709A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BE133796A 1972-07-24 1973-07-24 Nouveau produit actif pour le traitement de la leucemie a base d'acide n5 methiltetrahydrohomofulique ou des derives BE802709A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00274749A US3856959A (en) 1972-07-24 1972-07-24 Inhibition of leukemia utilizing 5-methyltetrahydrohomofolate

Publications (1)

Publication Number Publication Date
BE802709A true BE802709A (fr) 1973-11-16

Family

ID=23049461

Family Applications (1)

Application Number Title Priority Date Filing Date
BE133796A BE802709A (fr) 1972-07-24 1973-07-24 Nouveau produit actif pour le traitement de la leucemie a base d'acide n5 methiltetrahydrohomofulique ou des derives

Country Status (11)

Country Link
US (1) US3856959A (de)
JP (1) JPS5541207B2 (de)
AT (1) AT329312B (de)
AU (1) AU476551B2 (de)
BE (1) BE802709A (de)
CA (1) CA1006093A (de)
DE (1) DE2335898A1 (de)
FR (1) FR2193608B1 (de)
GB (1) GB1442772A (de)
NL (1) NL7309977A (de)
SE (1) SE431612B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1572137A (en) * 1977-02-22 1980-07-23 Bioresearch Sas Del Dr Livio C Stable compositions for therapeutic use based on d,1-5-methyltetrahydrofolic acid and its salts
US4927828A (en) * 1985-03-08 1990-05-22 The Trustees Of Princeton University Diastereoisomeric tetrahydropyrido-(2,3,d) pyrimidine derivatives
US5026851A (en) * 1985-03-08 1991-06-25 The Trustees Of Princeton University Pyrido[2,3-]pyrimidine derivatives
US4684653A (en) * 1985-03-08 1987-08-04 The Trustees Of Princeton University Pyrido(2,3-d)pyrimidine derivatives
US4833145A (en) * 1986-06-30 1989-05-23 The Trustees Of Princeton University 4(3H)-oxo-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidine derivatives
US4902796A (en) * 1986-10-20 1990-02-20 The Trustees Of Princeton University 6-alkenyl and ethynyl derivatives of 2-amino-4-hydroxypyrido[2,3-d]pyrimidines
US4818819A (en) * 1986-10-20 1989-04-04 The Trustees Of Princeton University Process for the preparation of fused pyridine compounds
US5028608A (en) * 1989-12-11 1991-07-02 The Trustees Of Princeton University N-(6-Amino-(pyrrolo(2,3-d)pyrimidin-3-ylacyl) )-glutamic acid derivatives
US9265746B2 (en) * 2006-05-31 2016-02-23 Merck & Cie Method for cell-specific targeting

Also Published As

Publication number Publication date
DE2335898A1 (de) 1974-02-07
AT329312B (de) 1976-05-10
NL7309977A (de) 1974-01-28
JPS5541207B2 (de) 1980-10-22
FR2193608B1 (de) 1976-08-13
AU476551B2 (en) 1976-09-30
CA1006093A (en) 1977-03-01
GB1442772A (en) 1976-07-14
JPS4950113A (de) 1974-05-15
US3856959A (en) 1974-12-24
SE431612B (sv) 1984-02-20
AU5782073A (en) 1975-01-09
FR2193608A1 (de) 1974-02-22
ATA633073A (de) 1975-07-15

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: GOUVERNEMENT DES ETATS-UNIS D AMERIQUE REPRESENTE

Effective date: 19840724