BE795238A - Derives d'insuline reticules de maniere intramoleculaire, leur procede de preparation et leur utilisation - Google Patents

Derives d'insuline reticules de maniere intramoleculaire, leur procede de preparation et leur utilisation

Info

Publication number
BE795238A
BE795238A BE795238DA BE795238A BE 795238 A BE795238 A BE 795238A BE 795238D A BE795238D A BE 795238DA BE 795238 A BE795238 A BE 795238A
Authority
BE
Belgium
Prior art keywords
preparation process
insulin derivatives
intramolecular cross
linked insulin
linked
Prior art date
Application number
Other languages
English (en)
French (fr)
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication date
Publication of BE795238A publication Critical patent/BE795238A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
BE795238D 1972-02-09 Derives d'insuline reticules de maniere intramoleculaire, leur procede de preparation et leur utilisation BE795238A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19722206826 DE2206826A1 (de) 1972-02-09 1972-02-09 Intramolekular vernetzte insulinderivate

Publications (1)

Publication Number Publication Date
BE795238A true BE795238A (fr) 1973-08-09

Family

ID=5835890

Family Applications (1)

Application Number Title Priority Date Filing Date
BE795238D BE795238A (fr) 1972-02-09 Derives d'insuline reticules de maniere intramoleculaire, leur procede de preparation et leur utilisation

Country Status (3)

Country Link
BE (1) BE795238A (OSRAM)
DE (1) DE2206826A1 (OSRAM)
NL (1) NL7300926A (OSRAM)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2253327A1 (de) * 1972-10-31 1974-05-09 Hoechst Ag Verfahren zur herstellung von insulin, insulin-analogen und -derivaten
NL7314766A (OSRAM) * 1972-10-31 1974-05-02
US6495136B1 (en) 1998-03-26 2002-12-17 The Procter & Gamble Company Proteases having modified amino acid sequences conjugated to addition moieties
JP2002507426A (ja) 1998-03-26 2002-03-12 ザ、プロクター、エンド、ギャンブル、カンパニー アミノ酸置換を有するセリンプロテアーゼ変異体
US6908757B1 (en) 1998-03-26 2005-06-21 The Procter & Gamble Company Serine protease variants having amino acid deletions and substitutions
CA2373680C (en) * 1999-05-17 2008-07-29 Conjuchem Inc. Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
KR20020021395A (ko) 1999-07-22 2002-03-20 데이비드 엠 모이어 입체적으로 보호된 ｃｌｉｐ 부위를 갖는 프로테아제콘쥬게이트
KR20020021397A (ko) 1999-07-22 2002-03-20 데이비드 엠 모이어 규정된 에피토프 영역에 아미노산 결실 및 치환을 갖는서브틸리신 프로테아제 변이체
KR20020029371A (ko) * 1999-07-22 2002-04-18 데이비드 엠 모이어 감소된 면역원성을 갖는 분자내 가교결합된 서브틸리신프로테아제
JP2003505070A (ja) 1999-07-22 2003-02-12 ザ、プロクター、エンド、ギャンブル、カンパニー 定められたエピトープ領域においてアミノ酸置換を有するサブチリシンプロテアーゼ変異体
US6946128B1 (en) 1999-07-22 2005-09-20 The Procter & Gamble Company Protease conjugates having sterically protected epitope regions

Also Published As

Publication number Publication date
DE2206826A1 (de) 1973-08-16
NL7300926A (OSRAM) 1973-08-13

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: SCHERING A.G.

Effective date: 19840209