BE776188A - Pyrrolidine-2-carboxylic acid -2-methyl-6-ethyl-anilides - useful as local anaesthetics - Google Patents
Pyrrolidine-2-carboxylic acid -2-methyl-6-ethyl-anilides - useful as local anaestheticsInfo
- Publication number
- BE776188A BE776188A BE776188A BE776188A BE776188A BE 776188 A BE776188 A BE 776188A BE 776188 A BE776188 A BE 776188A BE 776188 A BE776188 A BE 776188A BE 776188 A BE776188 A BE 776188A
- Authority
- BE
- Belgium
- Prior art keywords
- ethyl
- methyl
- carboxylic acid
- anilides
- pyrrolidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrrole Compounds (AREA)
Abstract
Novel title cpds of formula: (where R1 = H, alkyl or cycloalkyl) and their acid addition salts, are prepd. by reaction of a 2-methyl-6-ethyl-aniline magnesium halide with a pyrrolidene-2-carboxylic acid ester or a pyrrole-2-carboxylic ester, followed by hydrogenation.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BE776188A BE776188A (en) | 1971-12-03 | 1971-12-03 | Pyrrolidine-2-carboxylic acid -2-methyl-6-ethyl-anilides - useful as local anaesthetics |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BE776188A BE776188A (en) | 1971-12-03 | 1971-12-03 | Pyrrolidine-2-carboxylic acid -2-methyl-6-ethyl-anilides - useful as local anaesthetics |
Publications (1)
Publication Number | Publication Date |
---|---|
BE776188A true BE776188A (en) | 1972-06-05 |
Family
ID=3858958
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE776188A BE776188A (en) | 1971-12-03 | 1971-12-03 | Pyrrolidine-2-carboxylic acid -2-methyl-6-ethyl-anilides - useful as local anaesthetics |
Country Status (1)
Country | Link |
---|---|
BE (1) | BE776188A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0278089A3 (en) * | 1987-02-06 | 1989-01-25 | FISONS CORPORATION (a Massachusetts corporation) | 2-azacyclocarboxamide derivatives |
US5047541A (en) * | 1987-02-06 | 1991-09-10 | Fisons Corporation | 2-azacyclocarboxamide derivatives |
-
1971
- 1971-12-03 BE BE776188A patent/BE776188A/en unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0278089A3 (en) * | 1987-02-06 | 1989-01-25 | FISONS CORPORATION (a Massachusetts corporation) | 2-azacyclocarboxamide derivatives |
US5047541A (en) * | 1987-02-06 | 1991-09-10 | Fisons Corporation | 2-azacyclocarboxamide derivatives |
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