BE763298A - Derives de benzylimidazolidinone - Google Patents
Derives de benzylimidazolidinoneInfo
- Publication number
- BE763298A BE763298A BE763298A BE763298A BE763298A BE 763298 A BE763298 A BE 763298A BE 763298 A BE763298 A BE 763298A BE 763298 A BE763298 A BE 763298A BE 763298 A BE763298 A BE 763298A
- Authority
- BE
- Belgium
- Prior art keywords
- benzylimidazolidinone
- derivatives
- benzylimidazolidinone derivatives
- Prior art date
Links
- IXNSPEIJKZNYLL-UHFFFAOYSA-N 1-benzylimidazolidin-2-one Chemical class O=C1NCCN1CC1=CC=CC=C1 IXNSPEIJKZNYLL-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1376970A | 1970-02-24 | 1970-02-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE763298A true BE763298A (fr) | 1971-08-23 |
Family
ID=21761656
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE763298A BE763298A (fr) | 1970-02-24 | 1971-02-23 | Derives de benzylimidazolidinone |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US3636039A (pm) |
| JP (1) | JPS5421338B1 (pm) |
| BE (1) | BE763298A (pm) |
| BR (1) | BR7101125D0 (pm) |
| CA (1) | CA967163A (pm) |
| CH (2) | CH567482A5 (pm) |
| DE (1) | DE2108438C2 (pm) |
| DK (2) | DK134601B (pm) |
| FI (1) | FI54919C (pm) |
| FR (1) | FR2081537B1 (pm) |
| GB (1) | GB1292768A (pm) |
| IE (1) | IE35283B1 (pm) |
| IL (1) | IL36237A (pm) |
| NL (1) | NL171446C (pm) |
| NO (1) | NO130680C (pm) |
| SE (1) | SE369190B (pm) |
| YU (1) | YU34407B (pm) |
| ZA (1) | ZA711077B (pm) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3932452A (en) * | 1975-02-07 | 1976-01-13 | Morton-Norwich Products, Inc. | 1-Arylmethyl-2-imidazolidinones |
| US3966758A (en) * | 1975-06-16 | 1976-06-29 | Morton-Norwich Products, Inc. | Anti-inflammatory 1-(substituted benzyl)-2-imidazolidinones |
| US4063022A (en) * | 1976-11-22 | 1977-12-13 | Morton-Norwich Products, Inc. | Antisecretory 2-imidazolidinones |
| HU179019B (en) * | 1978-11-01 | 1982-08-28 | Gyogyszekutato Intezet | Process for preparing 4-//3,4-dialkoxy-phenyl/-alkyl/- 2imidazolidinone derivatives |
| CA1188616A (en) * | 1981-06-11 | 1985-06-11 | Hoffmann-La Roche Limited | Pharmaceutical preparations |
| FI875724L (fi) * | 1986-04-29 | 1987-12-28 | Pfizer | Av kalcium oberoende camp fosfodiesteras-inhibitordepressant. |
| US5459145A (en) * | 1988-01-19 | 1995-10-17 | Pfizer Inc. | Calcium independent camp phosphodiesterase inhibitor antidepressant |
| US5395935A (en) * | 1992-05-08 | 1995-03-07 | Pfizer Inc. | Endo-bicyclo[2.2.1]heptan-2-ol and derived pharmaceutical agents |
| GB9312853D0 (en) * | 1993-06-22 | 1993-08-04 | Euro Celtique Sa | Chemical compounds |
| US5591776A (en) * | 1994-06-24 | 1997-01-07 | Euro-Celtique, S.A. | Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV |
| US5922751A (en) * | 1994-06-24 | 1999-07-13 | Euro-Celtique, S.A. | Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same |
| US6025361A (en) * | 1994-12-13 | 2000-02-15 | Euro-Celtique, S.A. | Trisubstituted thioxanthines |
| EP0799040B1 (en) * | 1994-12-13 | 2003-08-20 | Euroceltique S.A. | Trisubstituted thioxanthines |
| WO1996018399A1 (en) * | 1994-12-13 | 1996-06-20 | Euro-Celtique, S.A. | Aryl thioxanthines |
| US6166041A (en) * | 1995-10-11 | 2000-12-26 | Euro-Celtique, S.A. | 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma |
| US6075016A (en) * | 1996-04-10 | 2000-06-13 | Euro-Celtique S.A. | 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity |
| US5864037A (en) * | 1996-06-06 | 1999-01-26 | Euro-Celtique, S.A. | Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity |
| US5744473A (en) * | 1996-09-16 | 1998-04-28 | Euro-Celtique, S.A. | PDE IV inhibitors: "bis-compounds" |
| EP1265861A2 (en) | 2000-03-16 | 2002-12-18 | Inflazyme Pharmaceuticals, Ltd. | Benzylated pde4 inhibitors |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| CN103601792B (zh) | 2007-06-04 | 2016-06-29 | 协同医药品公司 | 有效用于胃肠功能紊乱、炎症、癌症和其他疾病治疗的鸟苷酸环化酶激动剂 |
| CA2726917C (en) | 2008-06-04 | 2018-06-26 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| EP2321341B1 (en) | 2008-07-16 | 2017-02-22 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| CN108676076A (zh) | 2011-03-01 | 2018-10-19 | 辛纳吉制药公司 | 制备鸟苷酸环化酶c激动剂的方法 |
| HK1218629A1 (zh) | 2013-02-25 | 2017-03-03 | Bausch Health Ireland Limited | 用於结肠清洁的鸟苷酸环化酶受体激动剂 |
| CA2905438A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| US9486494B2 (en) | 2013-03-15 | 2016-11-08 | Synergy Pharmaceuticals, Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| SI3004138T1 (sl) | 2013-06-05 | 2024-07-31 | Bausch Health Ireland Limited | Ultra čisti agonisti gvanilat ciklaze C, postopek za njihovo pripravo in uporabo |
| MX375926B (es) | 2013-08-09 | 2025-03-07 | Ardelyx Inc | Compuestos y metodos para inhibir el transporte de fosfato. |
| EP3972599A1 (en) | 2019-05-21 | 2022-03-30 | Ardelyx, Inc. | Combination for lowering serum phosphate in a patient |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH518285A (de) * | 1968-05-01 | 1972-01-31 | Hoffmann La Roche | Verfahren zur Herstellung von neuen substituierten Benzylimidazolidinonen |
-
1970
- 1970-02-24 US US13769A patent/US3636039A/en not_active Expired - Lifetime
-
1971
- 1971-02-18 CH CH239371A patent/CH567482A5/xx not_active IP Right Cessation
- 1971-02-18 CH CH149474A patent/CH567483A5/xx not_active IP Right Cessation
- 1971-02-19 ZA ZA711077A patent/ZA711077B/xx unknown
- 1971-02-19 IL IL36237A patent/IL36237A/en unknown
- 1971-02-19 BR BR1125/71A patent/BR7101125D0/pt unknown
- 1971-02-22 DE DE2108438A patent/DE2108438C2/de not_active Expired
- 1971-02-22 IE IE213/71A patent/IE35283B1/xx unknown
- 1971-02-22 NL NLAANVRAGE7102324,A patent/NL171446C/xx not_active IP Right Cessation
- 1971-02-22 FI FI501/71A patent/FI54919C/fi active
- 1971-02-23 NO NO654/71A patent/NO130680C/no unknown
- 1971-02-23 YU YU439/71A patent/YU34407B/xx unknown
- 1971-02-23 BE BE763298A patent/BE763298A/xx not_active IP Right Cessation
- 1971-02-24 CA CA106,142A patent/CA967163A/en not_active Expired
- 1971-02-24 DK DK83171AA patent/DK134601B/da not_active IP Right Cessation
- 1971-02-24 SE SE02361/71A patent/SE369190B/xx unknown
- 1971-02-24 FR FR7106262A patent/FR2081537B1/fr not_active Expired
- 1971-02-24 JP JP923471A patent/JPS5421338B1/ja active Pending
- 1971-04-19 GB GB22437/71A patent/GB1292768A/en not_active Expired
-
1975
- 1975-12-15 DK DK570075A patent/DK570075A/da unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE2108438C2 (de) | 1987-02-05 |
| YU43971A (en) | 1978-12-31 |
| NL7102324A (pm) | 1971-08-26 |
| FI54919B (fi) | 1978-12-29 |
| IL36237A (en) | 1974-11-29 |
| NL171446B (nl) | 1982-11-01 |
| SE369190B (pm) | 1974-08-12 |
| ZA711077B (en) | 1971-10-27 |
| DK570075A (da) | 1975-12-15 |
| YU34407B (en) | 1979-07-10 |
| CH567483A5 (pm) | 1975-10-15 |
| IL36237A0 (en) | 1971-04-28 |
| IE35283L (en) | 1971-08-24 |
| IE35283B1 (en) | 1976-01-07 |
| NO130680C (pm) | 1975-01-22 |
| DK134601B (da) | 1976-12-06 |
| CH567482A5 (pm) | 1975-10-15 |
| FI54919C (fi) | 1979-04-10 |
| US3636039A (en) | 1972-01-18 |
| NL171446C (nl) | 1983-04-05 |
| JPS5421338B1 (pm) | 1979-07-30 |
| DE2108438A1 (de) | 1971-09-09 |
| DK134601C (pm) | 1977-05-16 |
| BR7101125D0 (pt) | 1973-04-26 |
| CA967163A (en) | 1975-05-06 |
| FR2081537A1 (pm) | 1971-12-03 |
| NO130680B (pm) | 1974-10-14 |
| GB1292768A (en) | 1972-10-11 |
| FR2081537B1 (pm) | 1974-08-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: F. HOFFMANN LA ROCHE & CIE S.A. Effective date: 19880228 |