BE651358A - - Google Patents
Info
- Publication number
- BE651358A BE651358A BE651358DA BE651358A BE 651358 A BE651358 A BE 651358A BE 651358D A BE651358D A BE 651358DA BE 651358 A BE651358 A BE 651358A
- Authority
- BE
- Belgium
- Prior art keywords
- group
- methoxy
- ethyl
- hydrogen
- compound according
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 claims description 12
- 229910052739 hydrogen Inorganic materials 0.000 claims description 10
- 239000001257 hydrogen Substances 0.000 claims description 10
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 9
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims description 8
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 8
- 238000005984 hydrogenation reaction Methods 0.000 claims description 7
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 7
- -1 hydroxymethylene Chemical group 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims 2
- 125000004429 atom Chemical group 0.000 claims 1
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 18
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 15
- 239000003054 catalyst Substances 0.000 description 8
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 description 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 125000000217 alkyl group Chemical group 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 239000012279 sodium borohydride Substances 0.000 description 3
- 229910000033 sodium borohydride Inorganic materials 0.000 description 3
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 125000004432 carbon atom Chemical group C* 0.000 description 2
- 239000013078 crystal Substances 0.000 description 2
- 238000001704 evaporation Methods 0.000 description 2
- 230000008020 evaporation Effects 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 239000011541 reaction mixture Substances 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 1
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 description 1
- 125000002252 acyl group Chemical group 0.000 description 1
- 125000002947 alkylene group Chemical group 0.000 description 1
- 230000008033 biological extinction Effects 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 150000001728 carbonyl compounds Chemical class 0.000 description 1
- 238000009903 catalytic hydrogenation reaction Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 150000002431 hydrogen Chemical class 0.000 description 1
- 239000000543 intermediate Substances 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 229910052744 lithium Inorganic materials 0.000 description 1
- 239000012280 lithium aluminium hydride Substances 0.000 description 1
- 229910052763 palladium Inorganic materials 0.000 description 1
- YWAKXRMUMFPDSH-UHFFFAOYSA-N pentene Chemical compound CCCC=C YWAKXRMUMFPDSH-UHFFFAOYSA-N 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- NARVIWMVBMUEOG-UHFFFAOYSA-N prop-1-en-2-ol Chemical group CC(O)=C NARVIWMVBMUEOG-UHFFFAOYSA-N 0.000 description 1
- 125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 238000009738 saturating Methods 0.000 description 1
- 238000007790 scraping Methods 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000006257 total synthesis reaction Methods 0.000 description 1
Landscapes
- Steroid Compounds (AREA)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE651358A true BE651358A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) |
Family
ID=206015
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE651358D BE651358A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) |
Country Status (1)
| Country | Link |
|---|---|
| BE (1) | BE651358A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) |
-
0
- BE BE651358D patent/BE651358A/fr unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2495960C (fr) | Nouveau procede de synthese du (7-methoxy-1-naphtyl)acetonitrile et application a la synthese de l'agomelatine | |
| FR2470135A1 (fr) | Procede de separation du b-sitosterol | |
| BE651358A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | ||
| FR2464270A1 (fr) | Nouveaux derives d'amino-14 steroides, et procede pour leur preparation | |
| EP0101383B1 (fr) | Dérivés d'amino-14 stéroides, application en thérapeutique, et procédé de préparation | |
| EP0486385A1 (fr) | Dérivés d'imidazole, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent | |
| EP0087359B1 (fr) | Nouveau réactif de nitrométhylation, son application à la préparation de composés nitrométhylénés et de certains de leurs dérivés et les composés nouveaux obtenus | |
| CH650516A5 (fr) | Derives steroides 20-isonitriles 17(20) insatures, leur procede de preparation et leur utilisation a la preparation des steroides 17alpha-hydroxy 20-ceto. | |
| KR20030033504A (ko) | 구굴스테론의 제조방법 | |
| Ogura et al. | Efficient 1, 2-asymmetric induction in radical reactions: Addition of acyl radicals to 3-hydroxy-1-(methylthio)-1-(p-tolylsulfonyl)-1-alkenes and their acetates | |
| FR2589469A1 (fr) | Procede de preparation de l'acide valproique | |
| EP0069010B1 (fr) | Procédé de préparation de composés carbonyles delta-éthyléniques | |
| CA1278316C (fr) | Methyl-3 alkoxy-1 hexatriene-1,3,5 et leurs utilisations pour la production d'aldehydes polyeniques | |
| EP0060767B1 (fr) | Procédé de préparation de composés carbonylés delta-éthyléniques | |
| WO2005030719A1 (fr) | Nouveau procede de preparation du cis-octahydro-isoindole | |
| EP0876361B1 (fr) | Dihydrate du (2r,3s)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionate de 4,10beta-diacetoxy-2alpha-benzoyloxy-5beta,20-epoxy-1-hydroxy-9-oxo-19-nor-cyclopropa g]tax-11-ene-13alpha-yle, et son procede de preparation | |
| EP0127536A1 (fr) | Procédé de préparation de composés carbonyles alpha-delta-diéthyléniques | |
| CH327513A (fr) | Procédé de préparation d'un dérivé du prégnane | |
| BE645393A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | ||
| EP0089908B1 (fr) | Nouveau procédé de préparation d'anhydrides d'acides carboxyliques | |
| CA2522482A1 (fr) | Procede de preparation du 4,10.beta.-diacetoxy-2.alpha.-benzoyloxy-5.beta.,20-epoxy-1,13.alpha.-dihydroxy-9-oxo-19-norcyclopropa[g]tax-11-ene | |
| JPS60184064A (ja) | フタルイミド誘導体 | |
| BE634058A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | ||
| BE477532A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | ||
| CH629826A5 (en) | Steroids, process for preparing them and their use in the synthesis of tritium-labelled steroids |