BE640917A - - Google Patents

Info

Publication number
BE640917A
BE640917A BE640917A BE640917A BE640917A BE 640917 A BE640917 A BE 640917A BE 640917 A BE640917 A BE 640917A BE 640917 A BE640917 A BE 640917A BE 640917 A BE640917 A BE 640917A
Authority
BE
Belgium
Prior art keywords
emi
quo
present
group
amino group
Prior art date
Application number
BE640917A
Other languages
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE640917A publication Critical patent/BE640917A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/69Benzenesulfonamido-pyrimidines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Description

  

   <EMI ID=1.1> 

  
La présente Invention concerne un nouveau

  
 <EMI ID=2.1> 

  

 <EMI ID=3.1> 


  
 <EMI ID=4.1> 

  
On prépare ce nouveau composé on faisant

  
réagir un soit en particulier un sol alcalin, d'un

  
 <EMI ID=5.1>  
 <EMI ID=6.1> 
 dont laquelle

  
 <EMI ID=7.1> 

  
lisation fractionnée, et on transformant, s'il est nécessaire, le groupe X on groupe amine libre. On effectua les réactions par exemple on chauffant dans 

  
 <EMI ID=8.1> 

  
auquel cas il pourra s'agir, par exemple, du groupe nitro ou do restes contenant des groupes azo substitues,

  
 <EMI ID=9.1>  

  
 <EMI ID=10.1> 

  
contiennent un reste X, hydrolysable on groupe amino, on peut effectuer l'hydrolyse du produit do 'condensation,

  
 <EMI ID=11.1> 

  
l'hydrolyse des composes alcoxycarbonylamino se fera également dans des conditions alcalinos douces, par

  
 <EMI ID=12.1> 

  
pyrimidino convient pour la préparation dos médicaments à usage interne et externe, destines par exemple au

  
 <EMI ID=13.1> 

  
i   <EMI ID=14.1> 

  
on solutions aqueuses pour injections, sous forma de

  
ses sols, par exemple do ses sels do sodium, do potassium, do lithium, do magnésium ou do calcium, ou encore sous

  
 <EMI ID=15.1> 

  
L'exemple suivant illustre la présente invention sans aucunomont on limiter la portée" EXEMPLE

  
 <EMI ID=16.1>   <EMI ID=17.1> 



   <EMI ID = 1.1>

  
The present invention relates to a new

  
 <EMI ID = 2.1>

  

 <EMI ID = 3.1>


  
 <EMI ID = 4.1>

  
We prepare this new compound by doing

  
react either in particular an alkaline sol, a

  
 <EMI ID = 5.1>
 <EMI ID = 6.1>
 which one

  
 <EMI ID = 7.1>

  
fractionalization, and transforming, if necessary, the group X or the free amine group. The reactions were carried out for example by heating in

  
 <EMI ID = 8.1>

  
in which case it may be, for example, the nitro group or residues containing substituted azo groups,

  
 <EMI ID = 9.1>

  
 <EMI ID = 10.1>

  
contain a residue X, hydrolyzable or an amino group, the hydrolysis of the condensation product can be carried out,

  
 <EMI ID = 11.1>

  
the hydrolysis of the alkoxycarbonylamino compounds will also take place under mild alkaline conditions, for example

  
 <EMI ID = 12.1>

  
pyrimidino is suitable for the preparation of medicaments for internal and external use, for example intended for

  
 <EMI ID = 13.1>

  
i <EMI ID = 14.1>

  
on aqueous solutions for injections, in the form of

  
its soils, for example of its sodium, potassium, lithium, magnesium or calcium salts, or

  
 <EMI ID = 15.1>

  
The following example illustrates the present invention without any limitation on the scope "EXAMPLE

  
 <EMI ID = 16.1> <EMI ID = 17.1>

 

Claims (1)

RE SUMB RE SUMB La présente invention comprend notamment t <EMI ID=18.1> The present invention comprises in particular t <EMI ID = 18.1> <EMI ID=19.1> <EMI ID = 19.1> ainsi quo los sols quo forme co composât thus quo los sols quo forme co composât <EMI ID=20.1> <EMI ID = 20.1> générale II general II <EMI ID=21.1> <EMI ID = 21.1> dans laquelle in which <EMI ID=22.1> <EMI ID = 22.1> formable en groupa amino, formable in amino group, <EMI ID=23.1> <EMI ID = 23.1> amino libres free amino
BE640917A 1962-12-07 1963-12-06 BE640917A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1445562 1962-12-07

Publications (1)

Publication Number Publication Date
BE640917A true BE640917A (en) 1964-06-08

Family

ID=4400963

Family Applications (1)

Application Number Title Priority Date Filing Date
BE640917A BE640917A (en) 1962-12-07 1963-12-06

Country Status (5)

Country Link
AT (1) AT245574B (en)
BE (1) BE640917A (en)
ES (2) ES294233A1 (en)
FR (2) FR1377697A (en)
NL (1) NL301455A (en)

Also Published As

Publication number Publication date
NL301455A (en) 1900-01-01
AT245574B (en) 1966-03-10
FR1377697A (en) 1964-11-06
ES294233A2 (en) 1964-05-16
FR3299M (en) 1965-05-10
ES294233A1 (en) 1964-05-16

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