BE522298A - - Google Patents

Info

Publication number

BE522298A

BE522298A BE522298DA BE522298A BE 522298 A BE522298 A BE 522298A BE 522298D A BE522298D A BE 522298DA BE 522298 A BE522298 A BE 522298A

Authority

BE

Belgium

Prior art keywords

tartaric acid

naphthoyl

acid

tartaric

aqueous acetone

Prior art date

Links

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• FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims description 8
• 229960001270 d- tartaric acid Drugs 0.000 claims description 8
• 238000000034 method Methods 0.000 claims description 5
• LNETULKMXZVUST-UHFFFAOYSA-N 1-naphthoic acid Chemical compound C1=CC=C2C(C(=O)O)=CC=CC2=C1 LNETULKMXZVUST-UHFFFAOYSA-N 0.000 claims description 4
• FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims description 4
• 229960001367 tartaric acid Drugs 0.000 claims description 4
• 235000002906 tartaric acid Nutrition 0.000 claims description 4
• 239000011975 tartaric acid Substances 0.000 claims description 4
• 230000015572 biosynthetic process Effects 0.000 claims description 2
• NSNPSJGHTQIXDO-UHFFFAOYSA-N naphthalene-1-carbonyl chloride Chemical compound C1=CC=C2C(C(=O)Cl)=CC=CC2=C1 NSNPSJGHTQIXDO-UHFFFAOYSA-N 0.000 claims description 2
• 238000003786 synthesis reaction Methods 0.000 claims 1
• CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 18
• UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 9
• 239000002253 acid Substances 0.000 description 6
• FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 description 6
• 238000002844 melting Methods 0.000 description 5
• 230000008018 melting Effects 0.000 description 5
• 150000008064 anhydrides Chemical class 0.000 description 4
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
• -1 (-naphthoyl) -D- tartaric acid Chemical compound 0.000 description 3
• VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 3
• 238000009835 boiling Methods 0.000 description 3
• 238000002425 crystallisation Methods 0.000 description 3
• 230000008025 crystallization Effects 0.000 description 3
• VMISPXWGYPAYCO-CLJLJLNGSA-N O[C@]([C@@](C(C1=CC=CC2=CC=CC=C12)=O)(C(O)=O)O)(C(C1=CC=CC2=CC=CC=C12)=O)C(O)=O Chemical compound O[C@]([C@@](C(C1=CC=CC2=CC=CC=C12)=O)(C(O)=O)O)(C(C1=CC=CC2=CC=CC=C12)=O)C(O)=O VMISPXWGYPAYCO-CLJLJLNGSA-N 0.000 description 2
• UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
• 238000007792 addition Methods 0.000 description 1
• 229930013930 alkaloid Natural products 0.000 description 1
• 238000007865 diluting Methods 0.000 description 1
• 238000004821 distillation Methods 0.000 description 1
• 238000001704 evaporation Methods 0.000 description 1
• 230000008020 evaporation Effects 0.000 description 1
• 230000004927 fusion Effects 0.000 description 1
• 150000004820 halides Chemical class 0.000 description 1
• 238000010438 heat treatment Methods 0.000 description 1
• 150000004678 hydrides Chemical class 0.000 description 1
• 239000012535 impurity Substances 0.000 description 1
• 238000004519 manufacturing process Methods 0.000 description 1
• 239000000203 mixture Substances 0.000 description 1
• 150000005209 naphthoic acids Chemical class 0.000 description 1
• 238000002360 preparation method Methods 0.000 description 1
• 150000003839 salts Chemical class 0.000 description 1
• 238000000926 separation method Methods 0.000 description 1
• 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
• 235000017557 sodium bicarbonate Nutrition 0.000 description 1