AU9794598A - Methods for detecting compounds which modulate the activity of an lpa receptor - Google Patents

Methods for detecting compounds which modulate the activity of an lpa receptor

Info

Publication number
AU9794598A
AU9794598A AU97945/98A AU9794598A AU9794598A AU 9794598 A AU9794598 A AU 9794598A AU 97945/98 A AU97945/98 A AU 97945/98A AU 9794598 A AU9794598 A AU 9794598A AU 9794598 A AU9794598 A AU 9794598A
Authority
AU
Australia
Prior art keywords
modulate
activity
methods
lpa receptor
detecting compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU97945/98A
Inventor
James Erikson
J. Graham Goddard
Michael Kiefer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LXR Biotechnology Inc
Original Assignee
LXR Biotechnology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LXR Biotechnology Inc filed Critical LXR Biotechnology Inc
Publication of AU9794598A publication Critical patent/AU9794598A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU97945/98A 1997-10-10 1998-10-09 Methods for detecting compounds which modulate the activity of an lpa receptor Abandoned AU9794598A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6157297P 1997-10-10 1997-10-10
US60061572 1997-10-10
PCT/US1998/021315 WO1999019513A2 (en) 1997-10-10 1998-10-09 Methods for detecting compounds which modulate the activity of an lpa receptor

Publications (1)

Publication Number Publication Date
AU9794598A true AU9794598A (en) 1999-05-03

Family

ID=22036653

Family Applications (1)

Application Number Title Priority Date Filing Date
AU97945/98A Abandoned AU9794598A (en) 1997-10-10 1998-10-09 Methods for detecting compounds which modulate the activity of an lpa receptor

Country Status (2)

Country Link
AU (1) AU9794598A (en)
WO (1) WO1999019513A2 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6037146A (en) * 1997-01-28 2000-03-14 Smithkline Beecham Corporation CDNA clone HE8CH90 that encodes a novel 7-transmembrane receptor
JP2002512016A (en) * 1998-04-23 2002-04-23 スミスクライン ビーチャム コーポレーション EDG family gene, human H218
US6380177B1 (en) 1999-06-25 2002-04-30 Atairgin Technologies, Inc. LPA analogs as agonists of the Edg2 LPA receptor
SE9902763D0 (en) * 1999-07-21 1999-07-21 Astra Pharma Inc Novel receptor
AU7057700A (en) * 1999-08-18 2001-03-13 Atairgin Technologies, Inc. Compounds which modulate the activity of an lpa receptor
GB9923890D0 (en) * 1999-10-08 1999-12-08 Pfizer Ltd Novel polypeptide
AU784543B2 (en) * 1999-11-16 2006-04-27 Pharmacia & Upjohn Company Novel G protein-coupled receptors
US20010041355A1 (en) * 2000-03-24 2001-11-15 Shyam Ramakrishnan Regulation of human nerve growth factor-related G protein-coupled receptor
WO2001073021A1 (en) * 2000-03-28 2001-10-04 Takeda Chemical Industries, Ltd. Novel g protein-coupled receptor protein and dna thereof
EP1178110A1 (en) * 2000-08-01 2002-02-06 Aventis Pharma Deutschland GmbH EDG8 receptor for sphingosine 1-phosphate , its preparation and use
MXPA02010241A (en) * 2000-04-26 2004-09-06 Aventis Pharma Gmbh Edg8 receptor, its preparation and use.
EP1149907A1 (en) * 2000-04-26 2001-10-31 Aventis Pharma Deutschland GmbH EDG8 receptor, its preparation and use
AU2001284732A1 (en) * 2000-08-04 2002-02-18 Genaissance Pharmaceuticals, Inc. Haplotypes of the edg4 gene
US7521192B2 (en) 2001-04-18 2009-04-21 Rigel Pharmaceuticals, Inc. EDG: modulators of lymphocyte activation and migration
EP1490111A2 (en) * 2001-11-30 2004-12-29 Solvay Pharmaceuticals GmbH Edg-receptor agonists for the treatment of hypertension
AU2003233119A1 (en) * 2002-05-08 2003-11-11 Neuronova Ab Modulation of neural stem cells with s1p or lpa receptor agonists
AU2003246726A1 (en) * 2002-07-31 2004-02-23 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with human g-protein coupled receptor 45 (gpr45)
EP1418185A1 (en) * 2002-11-11 2004-05-12 Aventis Pharma Deutschland GmbH Use of EDG2 receptor in an animal model of heart failure
US7169612B2 (en) 2002-11-11 2007-01-30 Sanofi-Aventis Deutschland Gmbh Use of EDG2 receptor in an animal model of heart failure
EP1579866A4 (en) * 2002-12-12 2009-07-29 Takeda Pharmaceutical Novel use of edg receptors
BR112012006686B8 (en) 2009-09-25 2021-05-25 Astellas Pharma Inc substituted amide compounds, pharmaceutical compositions containing said compounds, and their use to prevent and/or treat diseases caused by Lpa
MX2013003345A (en) 2010-09-24 2013-06-24 Astellas Pharma Inc Substituted amide compound.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992005244A1 (en) * 1990-09-13 1992-04-02 Duke University Expression of g protein coupled receptors in yeast
US5691188A (en) * 1994-02-14 1997-11-25 American Cyanamid Company Transformed yeast cells expressing heterologous G-protein coupled receptor
WO1995030012A1 (en) * 1994-04-26 1995-11-09 Cadus Pharmaceutical Corporation Functional expression of mammalian adenylyl cyclase in yeast
CA2224799A1 (en) * 1995-06-20 1997-01-09 Olga Bandman A human edg-2 receptor homolog
EP0862614A1 (en) * 1995-09-20 1998-09-09 Molecular Geriatrics Corporation Yeast receptor and g-protein fusion protein
CA2199455A1 (en) * 1997-03-07 1998-09-07 Jerold J. M. Chun Cloned lysophosphatidic acid receptors

Also Published As

Publication number Publication date
WO1999019513A2 (en) 1999-04-22
WO1999019513A3 (en) 1999-08-05

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase