AU8442291A - Hybrid plasminogen activators - Google Patents

Hybrid plasminogen activators

Info

Publication number
AU8442291A
AU8442291A AU84422/91A AU8442291A AU8442291A AU 8442291 A AU8442291 A AU 8442291A AU 84422/91 A AU84422/91 A AU 84422/91A AU 8442291 A AU8442291 A AU 8442291A AU 8442291 A AU8442291 A AU 8442291A
Authority
AU
Australia
Prior art keywords
plasminogen activators
hybrid plasminogen
hybrid
activators
plasminogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU84422/91A
Inventor
Michael Joseph Brown
Ian Dodd
Jeffery Hugh Robinson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of AU8442291A publication Critical patent/AU8442291A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU84422/91A 1990-09-01 1991-08-29 Hybrid plasminogen activators Abandoned AU8442291A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909019120A GB9019120D0 (en) 1990-09-01 1990-09-01 Novel compounds
GB9019120 1990-09-01

Publications (1)

Publication Number Publication Date
AU8442291A true AU8442291A (en) 1992-03-30

Family

ID=10681524

Family Applications (1)

Application Number Title Priority Date Filing Date
AU84422/91A Abandoned AU8442291A (en) 1990-09-01 1991-08-29 Hybrid plasminogen activators

Country Status (7)

Country Link
AU (1) AU8442291A (en)
GB (1) GB9019120D0 (en)
IE (1) IE913070A1 (en)
MX (1) MX9100886A (en)
PT (1) PT98823A (en)
WO (1) WO1992004450A1 (en)
ZA (1) ZA916903B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU648567B2 (en) * 1990-06-14 1994-04-28 Beecham Group Plc Hybrid plasminogen activators

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5801146A (en) * 1996-05-03 1998-09-01 Abbott Laboratories Compound and method for inhibiting angiogenesis
DE69733756T2 (en) * 1996-05-03 2006-06-01 Abbott Laboratories, Abbott Park ANTIANGIOGENIC PEPTIDES, POLYNUCLEOTIDES THAT CODE AND METHODS OF INHIBITING ANGIOGENESIS
US6699838B1 (en) 1996-05-03 2004-03-02 Abbott Laboratories Antiangiogenic peptides
CA2353699A1 (en) * 1998-12-02 2000-06-08 Oklahoma Medical Research Foundation Human plasminogen activator
CA2396739A1 (en) * 1999-12-06 2001-06-14 Krishna G. Peri Compositions for treating abnormalities in glomerular filtration, patent ductus arteriosus and osteoporosis

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988005081A2 (en) * 1986-12-30 1988-07-14 Cetus Corporation Novel plasminogen activator
GB8705377D0 (en) * 1987-03-07 1987-04-08 Beecham Group Plc Compounds
GB8711957D0 (en) * 1987-05-20 1987-06-24 Beecham Group Plc Compounds
EP0293934B1 (en) * 1987-06-04 1994-08-31 Zymogenetics, Inc. Mutant t-PA with kringle replacement
NO882886L (en) * 1987-07-01 1989-01-02 Beecham Group Plc NEW CONNECTIONS.
AU3410289A (en) * 1988-04-22 1989-11-24 Collaborative Research Inc. Plasminogen activators with increased fibrin selectivity
GB8901422D0 (en) * 1989-01-23 1989-03-15 Fujisawa Pharmaceutical Co New tissue plasminogen activator
DE3903581A1 (en) * 1989-02-07 1990-08-16 Boehringer Mannheim Gmbh FABRIC PLASMINOGEN ACTIVATOR DERIVATIVE
EP0397366A1 (en) * 1989-05-09 1990-11-14 The Board Of Regents Of The University Of Oklahoma Hybrid streptokinases with fibrin binding domains and methods for the synthesis of same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU648567B2 (en) * 1990-06-14 1994-04-28 Beecham Group Plc Hybrid plasminogen activators

Also Published As

Publication number Publication date
PT98823A (en) 1992-07-31
IE913070A1 (en) 1992-03-11
GB9019120D0 (en) 1990-10-17
WO1992004450A1 (en) 1992-03-19
MX9100886A (en) 1992-05-04
ZA916903B (en) 1992-12-30

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