AU8441798A - Tricyclically substituted oxazolidinones - Google Patents

Tricyclically substituted oxazolidinones

Info

Publication number
AU8441798A
AU8441798A AU84417/98A AU8441798A AU8441798A AU 8441798 A AU8441798 A AU 8441798A AU 84417/98 A AU84417/98 A AU 84417/98A AU 8441798 A AU8441798 A AU 8441798A AU 8441798 A AU8441798 A AU 8441798A
Authority
AU
Australia
Prior art keywords
substituted oxazolidinones
tricyclically
tricyclically substituted
oxazolidinones
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
AU84417/98A
Inventor
Stephan Bartel
Rainer Endermann
Walter Guarnieri
Dieter Habich
Hein-Peter Kroll
Siegfried Raddatz
Bernd dr. Riedl
Ulrich Rosentreter
Martin Dr. Ruppelt
Andreas Stolle
Hanno dr. Wild
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of AU8441798A publication Critical patent/AU8441798A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AU84417/98A 1997-07-18 1998-07-08 Tricyclically substituted oxazolidinones Withdrawn AU8441798A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19730847A DE19730847A1 (en) 1997-07-18 1997-07-18 Tricyclically substituted oxazolidinones
DE19730847 1997-07-18
PCT/EP1998/004252 WO1999003846A1 (en) 1997-07-18 1998-07-08 Tricyclically substituted oxazolidinones

Publications (1)

Publication Number Publication Date
AU8441798A true AU8441798A (en) 1999-02-10

Family

ID=7836119

Family Applications (1)

Application Number Title Priority Date Filing Date
AU84417/98A Withdrawn AU8441798A (en) 1997-07-18 1998-07-08 Tricyclically substituted oxazolidinones

Country Status (5)

Country Link
AR (1) AR016131A1 (en)
AU (1) AU8441798A (en)
DE (1) DE19730847A1 (en)
WO (1) WO1999003846A1 (en)
ZA (1) ZA986360B (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL345162A1 (en) 1998-06-05 2001-12-03 Astrazeneca Ab Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them
DE19905278A1 (en) * 1999-02-09 2000-08-10 Bayer Ag Oxazolidinones and their use as antibacterial agents
CN1367780A (en) * 1999-07-28 2002-09-04 法玛西雅厄普约翰美国公司 Oxazolidinones and their preparing method and use thereof
DE19962924A1 (en) 1999-12-24 2001-07-05 Bayer Ag Substituted oxazolidinones and their use
GB0010757D0 (en) 2000-05-05 2000-06-28 Astrazeneca Ab Chemical compounds
MXPA03003473A (en) 2000-10-17 2003-08-19 Upjohn Co Methods of producing oxazolidinone compounds.
US6958328B2 (en) 2001-04-18 2005-10-25 Ortho-Mcneil Pharmaceutical, Inc Arylindenopyridines and related therapeutic and prophylactic methods
US6903109B2 (en) 2001-04-18 2005-06-07 Ortho-Muniel Pharmaceutical, Inc. Arylindenopyridines and related therapeutic and prophylactic methods
DE10129725A1 (en) 2001-06-20 2003-01-02 Bayer Ag Combination therapy of substituted oxazolidinones
GB0121941D0 (en) 2001-09-11 2001-10-31 Astrazeneca Ab Chemical compounds
AR038536A1 (en) 2002-02-25 2005-01-19 Upjohn Co N-ARIL-2-OXAZOLIDINONA-5- CARBOXAMIDS AND ITS DERIVATIVES
US7141588B2 (en) 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
US20040127510A1 (en) 2002-04-16 2004-07-01 Heintzelman Geoffrey R. Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods
US7094900B2 (en) 2002-08-12 2006-08-22 Pharmacia & Upjohn Company Llc N-Aryl-2-oxazolidinones and their derivatives
AU2003280143A1 (en) 2002-11-21 2004-06-15 Pharmacia & Upjohn Company Llc N-(4-(piperazin-1-yl)-phenyl-2-oxazolidinone-5-carboxamide derivates and related compounds as antibacterial agents
GB0229521D0 (en) * 2002-12-19 2003-01-22 Astrazeneca Ab Chemical compounds
DE10300111A1 (en) 2003-01-07 2004-07-15 Bayer Healthcare Ag Process for the preparation of 5-chloro-N - ({(5S) -2-oxo-3- [4- (3-oxo-4-morpholinyl) phenyl] -1,3-oxazolidin-5-yl} methyl ) -2-thiophenecarboxamide
US7304050B2 (en) 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
DE10355461A1 (en) 2003-11-27 2005-06-23 Bayer Healthcare Ag Solid, high bioavailabilty oral formulations of N-substituted 5-chloro-2-thiophene-carboxamide derivative in hydrophilized form, useful for combating thrombo-embolic diseases
EP1685841A1 (en) 2005-01-31 2006-08-02 Bayer Health Care Aktiengesellschaft Prevention and treatment of thromboembolic disorders
DE102005045518A1 (en) 2005-09-23 2007-03-29 Bayer Healthcare Ag New 5-thienylaminocarbonylmethyl-oxazolidin-2-one derivatives, useful for treating and preventing thromboembolic disease, are selective inhibitors of coagulation factor Xa
DE102005047561A1 (en) 2005-10-04 2007-04-05 Bayer Healthcare Ag Drug delivery system, useful to treat and/or prevent e.g. thromboembolic disease, comprises 5-chloro-N-(((5S)-2-oxo-3-(4-(3-oxo-4-morpholinyl)-phenyl)-1,3-oxazolidine-5-yl)-methyl)-2-thiophene carboxamide with fast release active substance
CA2624310C (en) 2005-10-04 2014-01-07 Bayer Healthcare Ag Polymorphic form of 5-chloro-n-({5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophenecarboxamide
US8062442B1 (en) 2006-04-05 2011-11-22 University Of Central Florida Research Foundation, Inc. Safe, in situ methodologies for the destruction of triacetone triperoxide and other explosive peroxides
US7998992B2 (en) 2007-03-30 2011-08-16 Institute Of Medicinal Molecular Design, Inc. Oxazolidinone derivative having inhibitory activity on 11β-hydroxysteroid dehydrogenase type 1
ES2935615T3 (en) 2017-12-15 2023-03-08 Union Therapeutics As Azetidine substituted dihydrothienopyridines and their use as phosphodiesterase inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5254577A (en) * 1988-07-29 1993-10-19 The Du Pont Merck Pharmaceutical Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
DE68918792T2 (en) * 1988-09-15 1995-03-30 Upjohn Co 5-indolinyl-5-beta-amidomethyloxazolidin-2-one, 3- (substituted condensed) phenyl-5-beta amidomethyloxazolidin-2-one and 3- (nitrogen-substituted) phenyl-5-beta-amidomethyloxazolidin-2-one.
US5182296A (en) * 1989-10-26 1993-01-26 Tanabe Seiyaky Co., Ltd. Naphthyloxazolidone derivatives
AU667198B2 (en) * 1991-11-01 1996-03-14 Pharmacia & Upjohn Company Substituted aryl- and heteroarylphenyloxazolidinones useful as antibacterial agents
DE4425609A1 (en) * 1994-07-20 1996-01-25 Bayer Ag Benzofuranyl and Benzothienyloxazolidinone
FR2741071B1 (en) * 1995-11-09 1997-12-12 Synthelabo DERIVATIVES OF 3- (BENZOFURAN-5-YL) OXAZOLIDIN-2-ONE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Also Published As

Publication number Publication date
DE19730847A1 (en) 1999-01-28
AR016131A1 (en) 2001-06-20
ZA986360B (en) 1999-01-27
WO1999003846A1 (en) 1999-01-28

Similar Documents

Publication Publication Date Title
AU1251697A (en) New substituted oxazolidinones
AU1709299A (en) Mixer-injectors
AU8921698A (en) Follistatin-3
AU8441798A (en) Tricyclically substituted oxazolidinones
AU9414098A (en) Ascorbyl-phosphoryl-cholesterol
AU6598798A (en) Resorcinyl-triazines
AU1027499A (en) 32P-polyphosphazene
AU2616199A (en) Novel bicyclene-substituted oxazolidinones
AU9513298A (en) Fluoranthenopyrans
AU9066598A (en) Substituted 4-benzoyl-pyrazoles
AU5272198A (en) EMP-charge-eliminator
AU6394998A (en) Oxazolidines as 5-ht2a-antagonists
AU4117497A (en) Micropolarimeter
AU6998698A (en) Dioxacycloalkan-8-one
AU6185898A (en) Clavaspirins
AU7761998A (en) Korrosionsschutzanstrichstoff
AU8214598A (en) 3-benzylpiperidine
AU6090898A (en) Substituted 4-benzoyl-pyrazoles
AU4469997A (en) Heregulin-gamma
AU8991998A (en) Renovative pipeliner
AU5391798A (en) Thiamacrolides
AU9183798A (en) Catamaran - bicycle - kayak
AU7212698A (en) Substituted aryluracils
AU7530198A (en) Substituted 4-benzoyl-pyrazoles
AU5540298A (en) Rockbolts