AU780444B2 - Chlamydia antigens and corresponding DNA fragments and uses thereof - Google Patents
Chlamydia antigens and corresponding DNA fragments and uses thereof Download PDFInfo
- Publication number
- AU780444B2 AU780444B2 AU43885/00A AU4388500A AU780444B2 AU 780444 B2 AU780444 B2 AU 780444B2 AU 43885/00 A AU43885/00 A AU 43885/00A AU 4388500 A AU4388500 A AU 4388500A AU 780444 B2 AU780444 B2 AU 780444B2
- Authority
- AU
- Australia
- Prior art keywords
- ala
- polypeptide
- ser
- seq
- gin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/295—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Chlamydiales (O)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Otolaryngology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Cardiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13227099P | 1999-05-03 | 1999-05-03 | |
| US60/132270 | 1999-05-03 | ||
| US14127699P | 1999-06-30 | 1999-06-30 | |
| US60/141276 | 1999-06-30 | ||
| PCT/CA2000/000511 WO2000066739A2 (en) | 1999-05-03 | 2000-05-03 | Chlamydia antigens and corresponding dna fragments and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU4388500A AU4388500A (en) | 2000-11-17 |
| AU780444B2 true AU780444B2 (en) | 2005-03-24 |
Family
ID=26830227
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU43885/00A Ceased AU780444B2 (en) | 1999-05-03 | 2000-05-03 | Chlamydia antigens and corresponding DNA fragments and uses thereof |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US20030095973A1 (enExample) |
| EP (1) | EP1177301B1 (enExample) |
| JP (1) | JP4695763B2 (enExample) |
| AT (1) | ATE375391T1 (enExample) |
| AU (1) | AU780444B2 (enExample) |
| CA (1) | CA2373021A1 (enExample) |
| DE (1) | DE60036698T2 (enExample) |
| WO (1) | WO2000066739A2 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1105489A1 (en) | 1998-08-20 | 2001-06-13 | Aventis Pasteur Limited | Nucleic acid molecules encoding pomp91a protein of chlamydia |
| WO2000011181A1 (en) | 1998-08-20 | 2000-03-02 | Connaught Laboratories Limited | NUCLEIC ACID MOLECULES ENCODING INCLUSION MEMBRANE PROTEIN C OF $i(CHLAMYDIA) |
| US6686339B1 (en) | 1998-08-20 | 2004-02-03 | Aventis Pasteur Limited | Nucleic acid molecules encoding inclusion membrane protein C of Chlamydia |
| US6649370B1 (en) | 1998-10-28 | 2003-11-18 | Aventis Pasteur Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US6607730B1 (en) | 1998-11-02 | 2003-08-19 | Aventis Pasteur Limited/Aventis Pasteur Limitee | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| CA2353107A1 (en) | 1998-12-01 | 2000-06-08 | Andrew D. Murdin | Chlamydia antigens and corresponding dna fragments and uses thereof |
| AU772356B2 (en) * | 1998-12-04 | 2004-04-22 | Aventis Pasteur Limited | Two-step immunization procedure against chlamydia infection |
| US20020061848A1 (en) | 2000-07-20 | 2002-05-23 | Ajay Bhatia | Compounds and methods for treatment and diagnosis of chlamydial infection |
| IL143531A0 (en) | 1998-12-08 | 2002-04-21 | Corixa Corp | Polypeptides containing an antigenic portion of a chlamydia antigen, dna sequences encoding said polypeptides and pharmaceutical compositions and vaccines containing the same |
| GB9828000D0 (en) | 1998-12-18 | 1999-02-10 | Chiron Spa | Antigens |
| CA2354431A1 (en) * | 1998-12-23 | 2000-07-06 | Aventis Pasteur Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| US7297341B1 (en) | 1998-12-23 | 2007-11-20 | Sanofi Pasteur Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US6808713B1 (en) | 1998-12-28 | 2004-10-26 | Aventis Pasteur Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| AU774902B2 (en) | 1998-12-28 | 2004-07-15 | Aventis Pasteur Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| GB9902555D0 (en) | 1999-02-05 | 1999-03-24 | Neutec Pharma Plc | Medicament |
| CA2365196C (en) | 1999-03-12 | 2011-11-15 | Aventis Pasteur Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| EP1177301B1 (en) | 1999-05-03 | 2007-10-10 | Sanofi Pasteur Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| EP1220925B8 (en) | 1999-09-20 | 2008-04-23 | Sanofi Pasteur Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| US6632663B1 (en) | 1999-09-22 | 2003-10-14 | Aventis Pasteur Limited | DNA immunization against chlamydia infection |
| WO2001036455A2 (en) * | 1999-11-12 | 2001-05-25 | Aventis Pasteur Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| DE60044146D1 (de) * | 1999-12-22 | 2010-05-20 | Aventis Pasteur | D ihre verwendungen |
| US20020082402A1 (en) * | 2000-04-04 | 2002-06-27 | Murdin Andrew D. | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| AU2001255596A1 (en) | 2000-04-21 | 2001-11-07 | Corixa Corporation | Compounds and methods for treatment and diagnosis of chlamydial infection |
| US20040254130A1 (en) * | 2000-05-08 | 2004-12-16 | Murdin Andrew D | Chlamydia antigens and corresponding dna fragments and uses thereof |
| CA2408199A1 (en) | 2000-05-08 | 2001-11-15 | Aventis Pasteur Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| WO2002002606A2 (en) | 2000-07-03 | 2002-01-10 | Chiron S.P.A. | Immunisation against chlamydia pneumoniae |
| US20080112965A1 (en) * | 2001-10-01 | 2008-05-15 | Aventis Pasteur Limited | Chlamydia OMP antigen |
| US8568732B2 (en) | 2009-03-06 | 2013-10-29 | Novartis Ag | Chlamydia antigens |
| US9107875B2 (en) | 2009-11-18 | 2015-08-18 | Auburn University | Low antigen-dose immunization for maximizing T-helper cell 1 (Th1) immunity against a pathogen |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1331443C (en) * | 1987-05-29 | 1994-08-16 | Charlotte A. Kensil | Saponin adjuvant |
| US5283185A (en) * | 1991-08-28 | 1994-02-01 | University Of Tennessee Research Corporation | Method for delivering nucleic acids into cells |
| EP2045261A1 (en) * | 1994-09-20 | 2009-04-08 | Hitachi Chemical Co., Ltd. | Chlamydia pneumoniae antigenic polypeptides |
| FR2726764B1 (fr) * | 1994-11-14 | 1997-01-31 | Pasteur Merieux Serums Vacc | Adjuvant pour composition vaccinale |
| US5840788A (en) | 1997-06-20 | 1998-11-24 | Acushnet Company | Ultraviolet light resistant urethane top coat for golf balls |
| BR9810288A (pt) * | 1997-06-23 | 2000-09-19 | Loke Diagnostics Aps | Teste diagnóstico especìfico para espécie para identificar infecção de um mamìfero, como um humano, com chlamydia pneumoniae, fragmento de ácido nucleico derivado de chlamydia pneumoniae, proteìna derivada de chlamydia pneumoniae, anticorpo monoespecìfico policlonal, kit diagnóstico para o diagnóstico de infecção de um mamìfero, como um humano, com chlamydia pneumoniae, composição para imunizar um mamìfero comoum humano, contra chlamydia pneumoniae, uso de uma proteìna, e, uso de um fragmento de ácido nucleico. |
| US7459524B1 (en) * | 1997-10-02 | 2008-12-02 | Emergent Product Development Gaithersburg Inc. | Chlamydia protein, sequence and uses thereof |
| ATE352624T1 (de) * | 1997-11-21 | 2007-02-15 | Serono Genetics Inst Sa | Chlamydia pneumoniae genomische sequenzen und polypeptiden, fragmenten und anwendungen davon für nachweis, prevention und heilung |
| ES2352082T3 (es) | 1997-11-21 | 2011-02-15 | Merck Serono Biodevelopment | Polipéptido de la membrana externa de chlamydia pneumoniae, fragmentos del mismo y sus usos, en particular para el diagnóstico, la prevención y el tratamiento de una infección polipéptido de la membrana externa de chlamydia pneumoniae, fragmentos del mismo y sus usos, en particular para el diagnóstico, la prevención y el tratamiento de una infección. |
| KR100760221B1 (ko) | 1997-11-28 | 2007-10-30 | 세로노 제네틱스 인스티튜트 에스.에이. | 클라미디아 트라코마티스 게놈 서열과 폴리펩티드, 이의단편 및 이의 용도, 특히, 감염의 진단, 예방 및 치료 용도 |
| US6693087B1 (en) | 1998-08-20 | 2004-02-17 | Aventis Pasteur Limited | Nucleic acid molecules encoding POMP91A protein of Chlamydia |
| WO2000011181A1 (en) | 1998-08-20 | 2000-03-02 | Connaught Laboratories Limited | NUCLEIC ACID MOLECULES ENCODING INCLUSION MEMBRANE PROTEIN C OF $i(CHLAMYDIA) |
| CA2348827A1 (en) | 1998-10-28 | 2000-05-04 | Aventis Pasteur Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| WO2000027994A2 (en) | 1998-11-12 | 2000-05-18 | The Regents Of The University Of California | Chlamydia pneumoniae genome sequence |
| US6822071B1 (en) * | 1998-11-12 | 2004-11-23 | The Regents Of The University Of California | Polypeptides from Chlamydia pneumoniae and their use in the diagnosis, prevention and treatment of disease |
| CA2353107A1 (en) | 1998-12-01 | 2000-06-08 | Andrew D. Murdin | Chlamydia antigens and corresponding dna fragments and uses thereof |
| US6565856B1 (en) | 1998-12-08 | 2003-05-20 | Corixa Corporation | Compounds and methods for treatment and diagnosis of chlamydial infection |
| US20020061848A1 (en) | 2000-07-20 | 2002-05-23 | Ajay Bhatia | Compounds and methods for treatment and diagnosis of chlamydial infection |
| IL143531A0 (en) | 1998-12-08 | 2002-04-21 | Corixa Corp | Polypeptides containing an antigenic portion of a chlamydia antigen, dna sequences encoding said polypeptides and pharmaceutical compositions and vaccines containing the same |
| GB9828000D0 (en) | 1998-12-18 | 1999-02-10 | Chiron Spa | Antigens |
| US6808713B1 (en) | 1998-12-28 | 2004-10-26 | Aventis Pasteur Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| GB9902555D0 (en) | 1999-02-05 | 1999-03-24 | Neutec Pharma Plc | Medicament |
| EP1177301B1 (en) | 1999-05-03 | 2007-10-10 | Sanofi Pasteur Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| EP1220925B8 (en) | 1999-09-20 | 2008-04-23 | Sanofi Pasteur Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| US6632663B1 (en) | 1999-09-22 | 2003-10-14 | Aventis Pasteur Limited | DNA immunization against chlamydia infection |
| AU2138501A (en) | 1999-12-22 | 2001-07-03 | Aventis Pasteur Limited | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| DE60044146D1 (de) | 1999-12-22 | 2010-05-20 | Aventis Pasteur | D ihre verwendungen |
| US20020071831A1 (en) | 2000-04-04 | 2002-06-13 | Murdin Andrew D. | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US20020132994A1 (en) | 2000-04-04 | 2002-09-19 | Murdin Andrew D. | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US20020082402A1 (en) | 2000-04-04 | 2002-06-27 | Murdin Andrew D. | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US20020094965A1 (en) | 2000-04-04 | 2002-07-18 | Murdin Andrew D. | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| US20030100706A1 (en) | 2000-04-04 | 2003-05-29 | Murdin Andrew D. | Chlamydia antigens and corresponding DNA fragments and uses thereof |
| AU2001255596A1 (en) | 2000-04-21 | 2001-11-07 | Corixa Corporation | Compounds and methods for treatment and diagnosis of chlamydial infection |
| US20040254130A1 (en) | 2000-05-08 | 2004-12-16 | Murdin Andrew D | Chlamydia antigens and corresponding dna fragments and uses thereof |
| CA2408199A1 (en) | 2000-05-08 | 2001-11-15 | Aventis Pasteur Limited | Chlamydia antigens and corresponding dna fragments and uses thereof |
| WO2002002606A2 (en) | 2000-07-03 | 2002-01-10 | Chiron S.P.A. | Immunisation against chlamydia pneumoniae |
-
2000
- 2000-05-03 EP EP00925004A patent/EP1177301B1/en not_active Expired - Lifetime
- 2000-05-03 US US09/564,479 patent/US20030095973A1/en not_active Abandoned
- 2000-05-03 AU AU43885/00A patent/AU780444B2/en not_active Ceased
- 2000-05-03 CA CA002373021A patent/CA2373021A1/en not_active Abandoned
- 2000-05-03 JP JP2000615762A patent/JP4695763B2/ja not_active Expired - Fee Related
- 2000-05-03 WO PCT/CA2000/000511 patent/WO2000066739A2/en not_active Ceased
- 2000-05-03 AT AT00925004T patent/ATE375391T1/de active
- 2000-05-03 DE DE60036698T patent/DE60036698T2/de not_active Expired - Lifetime
-
2003
- 2003-06-30 US US10/608,559 patent/US7070792B2/en not_active Expired - Fee Related
-
2005
- 2005-05-02 US US11/118,381 patent/US7595058B2/en not_active Expired - Fee Related
-
2009
- 2009-02-09 US US12/367,955 patent/US7658934B2/en not_active Expired - Fee Related
Non-Patent Citations (2)
| Title |
|---|
| MELGOSA INFECT. IMMUN. 1994 62(3):880-86 * |
| TREMB AC. NO. Q927H7 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000066739A2 (en) | 2000-11-09 |
| DE60036698D1 (de) | 2007-11-22 |
| WO2000066739A3 (en) | 2001-01-11 |
| EP1177301B1 (en) | 2007-10-10 |
| US7070792B2 (en) | 2006-07-04 |
| US20050202048A1 (en) | 2005-09-15 |
| JP4695763B2 (ja) | 2011-06-08 |
| DE60036698T2 (de) | 2008-07-24 |
| US20090155350A1 (en) | 2009-06-18 |
| US7595058B2 (en) | 2009-09-29 |
| EP1177301A2 (en) | 2002-02-06 |
| CA2373021A1 (en) | 2000-11-09 |
| ATE375391T1 (de) | 2007-10-15 |
| JP2002542827A (ja) | 2002-12-17 |
| US7658934B2 (en) | 2010-02-09 |
| AU4388500A (en) | 2000-11-17 |
| US20040086525A1 (en) | 2004-05-06 |
| US20030095973A1 (en) | 2003-05-22 |
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