AU778090B2 - Methods for treating mild cognitive impairment - Google Patents

Methods for treating mild cognitive impairment Download PDF

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Publication number
AU778090B2
AU778090B2 AU19283/01A AU1928301A AU778090B2 AU 778090 B2 AU778090 B2 AU 778090B2 AU 19283/01 A AU19283/01 A AU 19283/01A AU 1928301 A AU1928301 A AU 1928301A AU 778090 B2 AU778090 B2 AU 778090B2
Authority
AU
Australia
Prior art keywords
glucocorticoid receptor
receptor antagonist
cortisol
patient
mci
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU19283/01A
Other languages
English (en)
Other versions
AU1928301A (en
Inventor
Joseph K. Belanoff
Alan F. Schatzberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Corcept Therapeutics Inc
Original Assignee
Corcept Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22607362&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU778090(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Corcept Therapeutics Inc filed Critical Corcept Therapeutics Inc
Publication of AU1928301A publication Critical patent/AU1928301A/en
Application granted granted Critical
Publication of AU778090B2 publication Critical patent/AU778090B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/46Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
AU19283/01A 1999-11-23 2000-11-21 Methods for treating mild cognitive impairment Expired AU778090B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16743299P 1999-11-23 1999-11-23
US60/167432 1999-11-23
PCT/US2000/032260 WO2001037840A1 (en) 1999-11-23 2000-11-21 Methods for treating mild cognitive impairment

Publications (2)

Publication Number Publication Date
AU1928301A AU1928301A (en) 2001-06-04
AU778090B2 true AU778090B2 (en) 2004-11-18

Family

ID=22607362

Family Applications (1)

Application Number Title Priority Date Filing Date
AU19283/01A Expired AU778090B2 (en) 1999-11-23 2000-11-21 Methods for treating mild cognitive impairment

Country Status (7)

Country Link
US (2) US6620802B1 (OSRAM)
EP (1) EP1242094A4 (OSRAM)
JP (1) JP2003527342A (OSRAM)
AU (1) AU778090B2 (OSRAM)
CA (1) CA2389570C (OSRAM)
HK (1) HK1047050A1 (OSRAM)
WO (1) WO2001037840A1 (OSRAM)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010046470A1 (en) * 2000-05-10 2001-11-29 Kieko Morita Diagnoses and treatment of disorders using an alternative glucose pathway
CN1820756A (zh) 2001-03-23 2006-08-23 科塞普特治疗公司 使用糖皮质激素受体特效拮抗剂治疗压力症的方法
NZ531477A (en) 2001-08-31 2006-10-27 Corcept Therapeutics Inc Use of a glucocorticoid receptor antagonist comprising a steroidal skeleton with at least one phenyl-containing moiety in the 11-beta position of the steroidal skeleton to decrease cognitive deterioration in adults with Down's syndrome
AU2003217046A1 (en) * 2002-04-05 2003-10-27 The University Of Edinburgh Pharmaceutical compositions comprising a 11-beta hydroxysteroid dehydrogenase inhibitor and a diuretic agent
US8237946B2 (en) * 2004-10-08 2012-08-07 Sharp Laboratories Of America, Inc. Methods and systems for imaging device accounting server redundancy
WO2006060736A2 (en) * 2004-12-03 2006-06-08 The Children's Hospital Of Philadelphia A composition and use thereof in enhancing a therapeutic effect of an antiepileptic drug
ES2865504T3 (es) * 2008-10-16 2021-10-15 Univ Johns Hopkins Procedimientos y composiciones para la mejora de la función cognitiva
US20110202284A1 (en) * 2010-02-10 2011-08-18 Mcreynolds Cristopher Novel groups of biomarkers for diagnosing alzheimer's disease
US10500216B2 (en) 2011-11-18 2019-12-10 Corcept Therapeutics, Inc. Optimizing mifepristone absorption
WO2014074744A1 (en) * 2012-11-09 2014-05-15 Lasser Elliott C X-ray contrast media compositions and methods of using the same to treat inflammation associated conditions
JP6440625B2 (ja) 2012-11-14 2018-12-19 ザ・ジョンズ・ホプキンス・ユニバーシティー 精神分裂病を処置するための方法および組成物
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
CN105142623A (zh) 2013-03-15 2015-12-09 艾吉因生物股份有限公司 用于改善认知功能的方法和组合物
US9943526B2 (en) 2015-04-21 2018-04-17 Corcept Therapeutics, Inc. Optimizing mifepristone levels for cushing's patients
NZ738682A (en) 2015-05-22 2022-01-28 Agenebio Inc Extended release pharmaceutical compositions of levetiracetam

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3337450A1 (de) * 1983-10-12 1985-04-25 Schering AG, 1000 Berlin und 4709 Bergkamen Prostaglandine und antigestagene fuer den schwangerschaftsabbruch
CA2250874A1 (en) 1996-04-09 1997-10-16 Btg International Limited Use of 7 alpha-substituted steroids to treat neuropsychiatric, immune or endocrine disorders
DK1023074T3 (da) * 1997-10-06 2006-11-06 Univ Leland Stanford Junior Fremgangsmåder til behandling af psykose forbundet med glucocorticoid-relateret dysfunktion
JP2003505336A (ja) 1998-05-15 2003-02-12 ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティ 痴呆の処置のためのグルココルチコイドレセプターアンタゴニスト

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BEHL ET AL, EUR. JNL. OF NEUROSCIENCE 1997 VOL 9 PP912-920 *
TUOR ET AL, BRAIN RESEARCH, 1996, VOL 743, PP258-262 *

Also Published As

Publication number Publication date
US6620802B1 (en) 2003-09-16
CA2389570A1 (en) 2001-05-31
US20040019028A1 (en) 2004-01-29
JP2003527342A (ja) 2003-09-16
AU1928301A (en) 2001-06-04
WO2001037840A1 (en) 2001-05-31
EP1242094A1 (en) 2002-09-25
HK1047050A1 (zh) 2003-02-07
EP1242094A4 (en) 2004-06-16
CA2389570C (en) 2012-03-27

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Legal Events

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MK14 Patent ceased section 143(a) (annual fees not paid) or expired