AU777550B2 - Protease conjugates having sterically protected epitope regions - Google Patents

Protease conjugates having sterically protected epitope regions Download PDF

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Publication number
AU777550B2
AU777550B2 AU59283/00A AU5928300A AU777550B2 AU 777550 B2 AU777550 B2 AU 777550B2 AU 59283/00 A AU59283/00 A AU 59283/00A AU 5928300 A AU5928300 A AU 5928300A AU 777550 B2 AU777550 B2 AU 777550B2
Authority
AU
Australia
Prior art keywords
protease
moiety
amino acid
conjugate according
epitope
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU59283/00A
Other languages
English (en)
Other versions
AU5928300A (en
Inventor
Paul Elliott Correa
Donn Nelton Rubingh
David John Weisgerber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Publication of AU5928300A publication Critical patent/AU5928300A/en
Application granted granted Critical
Publication of AU777550B2 publication Critical patent/AU777550B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Detergent Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cosmetics (AREA)
AU59283/00A 1999-07-22 2000-07-11 Protease conjugates having sterically protected epitope regions Ceased AU777550B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14497999P 1999-07-22 1999-07-22
US60/144979 1999-07-22
PCT/US2000/018854 WO2001007577A2 (en) 1999-07-22 2000-07-11 Protease conjugates having sterically protected epitope regions

Publications (2)

Publication Number Publication Date
AU5928300A AU5928300A (en) 2001-02-13
AU777550B2 true AU777550B2 (en) 2004-10-21

Family

ID=22511045

Family Applications (1)

Application Number Title Priority Date Filing Date
AU59283/00A Ceased AU777550B2 (en) 1999-07-22 2000-07-11 Protease conjugates having sterically protected epitope regions

Country Status (10)

Country Link
EP (1) EP1196547A2 (zh)
JP (1) JP2003505069A (zh)
KR (1) KR20020021396A (zh)
CN (1) CN1372593A (zh)
AU (1) AU777550B2 (zh)
BR (1) BR0012692A (zh)
CA (1) CA2379723A1 (zh)
CZ (1) CZ2002211A3 (zh)
MX (1) MXPA02000837A (zh)
WO (1) WO2001007577A2 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7432331B2 (en) 2002-12-31 2008-10-07 Nektar Therapeutics Al, Corporation Hydrolytically stable maleimide-terminated polymers
EP2105494B1 (en) 2008-03-25 2019-05-08 Diversey, Inc. A method of lubricating a conveyor belt
EP2105493B1 (en) 2008-03-25 2014-05-14 Diversey, Inc. Dry lubrication method employing oil-based lubricants
WO2010056653A2 (en) 2008-11-11 2010-05-20 Danisco Us Inc. Proteases comprising one or more combinable mutations
WO2010056640A2 (en) * 2008-11-11 2010-05-20 Danisco Us Inc. Compositions and methods comprising serine protease variants

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0471125A1 (en) * 1989-02-20 1992-02-19 Kanebo, Ltd. Modified protease, method of producing the same and cosmetic compositions containing the modified protease
US5856451A (en) * 1994-12-07 1999-01-05 Novo Nordisk A/S Method for reducing respiratory allergenicity
WO1999000489A1 (en) * 1997-06-25 1999-01-07 Novo Nordisk A/S A modified polypeptide

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4844897A (en) * 1985-09-13 1989-07-04 Hiroshi Maeda Anti-tumor protease preparations
EP0561907B1 (en) * 1990-12-05 1998-09-02 Novo Nordisk A/S Proteins with changed epitopes and methods for the production thereof
US6946280B1 (en) * 1996-03-29 2005-09-20 Genencor International, Inc. Enzyme multimer and process of producing same
CA2273079C (en) * 1996-11-26 2012-04-10 Genencor International, Inc. Chemically modified subtilisin mutants
EP1047445B1 (en) * 1998-01-23 2013-08-28 The Governing Council Of The University Of Toronto Modified enzymes and their use for peptide synthesis
US6495136B1 (en) * 1998-03-26 2002-12-17 The Procter & Gamble Company Proteases having modified amino acid sequences conjugated to addition moieties
WO2000028007A2 (en) * 1998-11-10 2000-05-18 Genencor International, Inc. Chemically modified mutant serine hydrolases
DK1141335T3 (da) * 1998-12-21 2009-11-09 Genencor Int Kemisk modificerede enzymer med multipelt ladede varianter

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0471125A1 (en) * 1989-02-20 1992-02-19 Kanebo, Ltd. Modified protease, method of producing the same and cosmetic compositions containing the modified protease
US5856451A (en) * 1994-12-07 1999-01-05 Novo Nordisk A/S Method for reducing respiratory allergenicity
WO1999000489A1 (en) * 1997-06-25 1999-01-07 Novo Nordisk A/S A modified polypeptide

Also Published As

Publication number Publication date
BR0012692A (pt) 2002-04-09
CA2379723A1 (en) 2001-02-01
KR20020021396A (ko) 2002-03-20
EP1196547A2 (en) 2002-04-17
CZ2002211A3 (cs) 2002-05-15
WO2001007577A2 (en) 2001-02-01
WO2001007577A3 (en) 2001-08-30
JP2003505069A (ja) 2003-02-12
MXPA02000837A (es) 2002-07-30
CN1372593A (zh) 2002-10-02
AU5928300A (en) 2001-02-13

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