AU773303B2 - Device and method for filling containers in a sterile manner - Google Patents

Device and method for filling containers in a sterile manner Download PDF

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Publication number
AU773303B2
AU773303B2 AU12703/01A AU1270301A AU773303B2 AU 773303 B2 AU773303 B2 AU 773303B2 AU 12703/01 A AU12703/01 A AU 12703/01A AU 1270301 A AU1270301 A AU 1270301A AU 773303 B2 AU773303 B2 AU 773303B2
Authority
AU
Australia
Prior art keywords
containers
clean room
cleaning
cleaned
sealing cap
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU12703/01A
Other versions
AU1270301A (en
Inventor
Wolfhard Schwarz
Gunther Spatz
Karl-Heinz Spether
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Closure Systems International Deutschland GmbH
Original Assignee
Alcoa Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10041319A external-priority patent/DE10041319A1/en
Application filed by Alcoa Deutschland GmbH filed Critical Alcoa Deutschland GmbH
Publication of AU1270301A publication Critical patent/AU1270301A/en
Application granted granted Critical
Publication of AU773303B2 publication Critical patent/AU773303B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/20Gaseous substances, e.g. vapours
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08Radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08Radiation
    • A61L2/10Ultraviolet radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/20Gaseous substances, e.g. vapours
    • A61L2/202Ozone
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B67OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
    • B67CCLEANING, FILLING WITH LIQUIDS OR SEMILIQUIDS, OR EMPTYING, OF BOTTLES, JARS, CANS, CASKS, BARRELS, OR SIMILAR CONTAINERS, NOT OTHERWISE PROVIDED FOR; FUNNELS
    • B67C7/00Concurrent cleaning, filling, and closing of bottles; Processes or devices for at least two of these operations
    • B67C7/0073Sterilising, aseptic filling and closing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B67OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
    • B67CCLEANING, FILLING WITH LIQUIDS OR SEMILIQUIDS, OR EMPTYING, OF BOTTLES, JARS, CANS, CASKS, BARRELS, OR SIMILAR CONTAINERS, NOT OTHERWISE PROVIDED FOR; FUNNELS
    • B67C7/00Concurrent cleaning, filling, and closing of bottles; Processes or devices for at least two of these operations
    • B67C7/0073Sterilising, aseptic filling and closing
    • B67C7/008Sterilising, aseptic filling and closing comprising a cleaning step between two closing steps

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Filling Of Jars Or Cans And Processes For Cleaning And Sealing Jars (AREA)
  • Basic Packing Technique (AREA)
  • Packages (AREA)

Abstract

The invention relates to a device for filling containers, in particular, for filling bottles with perishable goods. Said device comprises a filling station and is characterised by a clean room (3), in which the containers (B) are filled and preferably sealed with a closure (V) in a sealing station (7). The device also has a first cleaning sluice (13) for the containers (B) which is allocated to the clean room (3), in such a way that the containers (B) are cleaned before entering said clean room (3).

Description

-1- Device and Method for Filling Containers Field of the Invention This invention relates to a device for filling containers, in particular bottles.
Background of the Invention Devices and methods of the type discussed here are known. However it has been found that particularly when the containers are being filled with perishable substances, in particular with beer, fruit juices or still mineral water, the substance with which, the containers are filled becomes contaminated and therefore perishes rapidly, so that it is no longer suitable for consumption.
Object of the Invention It is an object of the present invention to overcome or ameliorate some of the disadvantages of the prior art, or at least to provide a useful alternative.
Summary of the Invention There is firstly disclosed herein a device for filling containers, in particular 15 bottles, with a perishable substance and for closing with a multi-part closure, having a sealing cap and a closure element, said device having: a filling station; a clean room in which the containers are filled and are closed by means of a sealing cap in a closure station; a first cleaning lock for the containers, which is assigned to the clean room in such a way that the containers are cleaned before they enter the clean room; a second cleaning lock for the sealing cap or closures, which is assigned to the clean room in such a way that the sealing caps or the closures are cleaned before they enter the clean room.
25 There is further disclosed herein a method for filling containers, in particular bottles, with perishable goods, said method including the following steps: introducing a container into a first cleaning lock; transferring the container from the first cleaning lock into a clean room; introducing a sealing cap into a second cleaning lock; transferring the sealing cap from the second cleaning lock to said clean room; filling the container in the clean room and closing the container by a first part of a multi-part closure, namely a sealing cap.
[R:\LIBLL] 1 4 75 7 spcci.doc:keh -2- The term clean room preferably means an environment within which the number of germs is extremely low and which is virtually free of substances which are hazardous to the perishable substance. A closure station is also preferably provided in the clean room. Therefore, the containers are closed with a closure in the clean room, so that it is impossible for any germs to enter the container during transfer from the filling station to the closure station. The clean room is assigned at least a first cleaning lock, in which the containers are cleaned before they enter the clean room.
An exemplary embodiment of the device which is distinguished by the fact that a second cleaning lock is provided, which is used to clean the closures which are fitted onto the containers, is preferred. This also ensures that it is impossible for any germs or the like to be carried into the clean room.
The containers are preferably fed to a clean room, inside which they are filled, via a first cleaning lock, in which they are cleaned. The containers are also closed in the clean room, in order to prevent germs or other substances from being carried into the Is perishable substance.
Brief Description of the Drawings A preferred embodiment of the invention will now be described, by way of example only, with reference to the accompanying drawing, wherein: Figure 1 shows a device 1 inside which containers are filled with a perishable substance.
Detailed Description of the Preferred Embodiments •ooo The device 1 has a clean room 3 which is distinguished by the fact that the number of germs per cubic meter of air and of other substances which have an adverse oo• effect on the perishable substance are reduced to a minimum.
o oo 25 Inside the device 1 there is a filling station 5 in which the perishable substance is introduced into the containers B. The device 1 illustrated in this figure also comprises a closure station 7, inside which closures V are fitted to the filled containers B. The closure station 7 is preferably likewise arranged in the clean room 3, i.e. inside the device 1, in order to avoid germs or other substances from posing a risk to the perishable substance when the containers B are transferred from the filling station 5 to the closure station 7.
In Figure 1, a downstream cleaning station 9 is indicated in dashed lines inside the device 1. This is [R:\LI BLL] 14757spcci.doc:keh 3 used to clean the filled containers B, so that there is no perishable substance or other substances adhering to the outside thereof. Figure 1 indicates that the downstream cleaning station may also be provided outside the device 1. The cleaning station arranged outside the device 1 is denoted by reference numeral 11.
It can be seen from Figure 1 that a first cleaning lock 13 is provided, which is fed with the containers B to be filled. Inside the cleaning lock 13, the containers B are cleaned, .preferably sterilized.
The lock may comprise a blasting device and/or a gasification device, the blasting device being able to spray a liquid onto the containers B to be cleaned and/or to emit UV or radioactive radiation. Devices of this type are known, and therefore will not be described here.
The cleaned containers B are fed from the first cleaning lock 13 to the device 1 in such a way that there is no possibility of contamination of the containers B. The first cleaning lock 13 may therefore be directly connected to the device 1.
Figure 1 also shows a second cleaning lock which is fed with the closures V which are used to close the containers B. Inside the second cleaning lock the closures V are cleaned and/or disinfected; in this case too, it is possible to use a blasting device of the abovementioned type and/or a gasification device.
From the second cleaning lock 15, the closures V are fed to the device 1 in such a way that there is no possibility of contamination by germs or other substances.
A dashed line 17 indicates that on theone hand the first and second cleaning locks 13 and 15 may be combined to form a single lock, and on the other hand the itwo locks may-be directly connected to the device 1, in order to be able to .ensure that the dleaned 4 objects are transferred securely, i.e. with protection against contamination.
The objects to be cleaned, i.e. the containers B and the closures V, can therefore be cleaned in the associated cleaning locks by a gasification device which emits ozone, for example, or by means of a blasting device. The blasting device can release a cleaning liquid onto the objects to be cleaned or can emit UV radiation or radioactive radiation. Following the cleaning by means of an active washing liquid, it is possible to carry out downstream cleaning using a neutral medium, in order to eliminate all residues of the cleaning liquid. The downstream cleaning preferably takes place outside the clean room, which can thus be of relatively compact-design.
The way in which the device 1 functions and the method for filling containers will be dealt with in more detail below: In the interior of the device 1, namely in the clean room 3, containers B are filled with perishable substance, for example with fruit juices or with mineral water which has a low carbon dioxide content or contains no carbon dioxide, in a filling station 5. In the latter case, therefore, the disinfecting action of carbon dioxide:is absent.
To prevent germs from being introduced into the containers B, the containers B and preferably also the closures V are cleaned and/or disinfected in cleaning locks 13 and 15 or, if appropriate,. in a common cleaning lock (cf. line 17). The containers B are then fed to the filling station 5, the closures V to the closure station In this way, it is possible to fill the containers B with perishable' substance and to prevent germs or other disruptive substances from being entrained. Therefore, with the aid of the device 1 and the method explained here, it is. possible 'for containers B to be filled without there being any need .for heating of the substance to be introduced. On the one hand, this contributes to the flavour :-and 5 constituents, in particular vitamins, of the substance with which the containers are to be filled not being impaired, and on the other hand it is possible to save on the energy required to heat the substance.
Ultimately, the method and device contribute to reliably achieving the minimum shelf life required, and in many cases this shelf life can even be extended, in some cases considerably.
The closed containers B may also be cleaned in a downstream cleaning station 9 .inside the clean room 3. However, it is expedient for the downstream cleaning to be carried out outside the device 1 or the clean room 3, in a downstream cleaning station 11.
Overall, it becomes clear that the device 1 is of very simple structure and that it is possible to use standard cleaning and disinfecting methods for cleaning and disinfecting the objects which have been introduced into the clean room 3, namely the containers B and if appropriate also the closures in such a way that there are no germs or other substances entrained into the perishable substance.
The explanations given also make it clear that it is simple to.produce cleaning locks 1,3, 15 which can be directly integrated in the housing wall of the device 1 or can be fitted to this wall. Germs' cannot enter the clean room.3 or the area on the other side of the housing wall, since the only access is through the cleaning locks.
In the end, it can be seen clearly that in the device described here or when carrying out the method explained, containers are filled and closed in a clean room. In doing so, at least. one cleaning lock is used to ensure. that. the. objects which are introduced into the clean room,' in this. case therefore the containers and the closures, are cleaned, so that it is impossible for germs to be introduced. :It can easily be seen-that it is possible to use a, cleaning' lock which- is provided for both -the containers .and the :closures,. but that it 6is also possible to provide separate cleaning locks for the two elements.
The device and the method are suitable for containers and closures of all types.. However, it has emerged that in some cases there are areas of closures which are not readily accessible and in which it is possible that there may still be germs. Therefore, it is preferable to use particular types of closure which are of very simple structure, i.e. from which germs can be completely removed very easily during a cleaning operation.
The particular closures of the type discussed here are, as it were, simple closure caps, also referred to as sealing caps, which can be fitted onto the container in the interior of the clean room and reliably close this container. The containers are then preferably definitively closed outside the clean room by a closure element being fitted to the closure cap.
This may be a conventional plastic screw-type cap, a crown cap, a twist crown cap or a standard metal screwtype cap. Screw-type caps of this type are fitted onto the container which has been provided with the closure cap and are then subjected to a forming operation in which a thread is rolled into the lateral surface of the screw-type cap. Forming processes of this type are generally known and therefore need no further explanation here.
It is also essential that closure caps which are preferably -of simple structure are used, without any undercuts -or areas in which germs or the like may remainduring a cleaning operation, thus constituting a hazard to the filling substance. The containers can be securely closed by means of the closure caps,. so that contamination of the- container content, is reliably avoided even after they. have been taken out of the clean room. The containers are therefore easy to handle without risk of the contents being damaged and can be definitively closed in the manner referred to above.
7 The closure caps may consist of plastic, of plasticcoated metal or of a plurality of materials.
Preferably, the closure caps are fed to the cleaning lock in a defined orientation, so that it is impossible for any liquid residues to collect in the closure cap during cleaning with a liquid cleaning or disinfecting agent.
The simple structure of the closure caps, which in fact have no undercuts or the like is also advantageous for cleaning methods using jets and beams of all kinds, since all areas of the closure cap can be reliably reached and germs and the like are killed.
During cleaning of the closure caps which are held at a particularly selected orientation, it is possible to ensure that cleaning liquid does not collect in recesses or the like. Consequently, drying processes which follow the cleaning operation can be carried out particularly efficiently and quickly.
During, cleaning of the containers and the closures or closure caps, it should be ensured that the materials of the parts to be cleaned are not impaired and that the taste of the substances or liquids with which, the container is filled is not adversely affected either. By way of example, peracetic acid' and/or alcohol can be used for the cleaning.
The device described here and the method explained can be used particularly effectively for filling containers with readily perishable substance, in particular with beer, fruit juices and mineral water with a low carbon dioxide content or without any carbon dioxide. In this case, it is preferable to use the closure caps described which are referred to as sealing caps, since such caps can be. cleaned very thoroughly.

Claims (9)

1. A device for filling containers, in particular bottles, with a perishable substance and for closing with a multi-part closure, having a sealing cap and a closure element, said device having: a filling station; a clean room in which the containers are filled and are closed by means of a sealing cap in a closure station; a first cleaning lock for the containers, which is assigned to the clean room in such a way that the containers are cleaned before they enter the clean room; a second cleaning lock for the sealing cap or closures, which is assigned to the clean room in such a way that the sealing caps or the closures are cleaned before they enter the clean room.
2. The device according to claim 1, wherein the first and/or second **cleaning locks include a spray device and/or a gassing device. Is
3. The device according to claim 2, wherein the spray device effuses a liquid, a UV radiation, a radioactive radiation and/or gas onto the articles to be cleaned. cen
4. The device according to any one of claims 1 to 3, wherein a post- cleaning station is provided.
A method for filling containers, in particular bottles, with perishable goods, said method including the following steps: introducing a container into a first cleaning lock; transferring the container from the first cleaning lock into a clean room; introducing a sealing cap into a second cleaning lock; transferring the sealing cap from the second cleaning lock to said clean room; filling the container in the clean room and closing the container by a first part of S•a multi-part closure, namely a sealing cap.
6. The method according to claim 5, wherein the container and/or the sealing cap is cleaned in the cleaning lock by means of a spray device and/or by means of a gassing device.
7. The method according to claim 5 or 6, wherein the articles to be cleaned are cleaned by means of liquid sprays, UV rays, radioactive rays and/or by a gas.
8. A device for filling containers, substantially as herein described with reference to any one of the embodiments of the invention shown in the accompanying drawings. [R:\LIBLL]I 4 7 5 7 spcci.doc:keh -9-
9. A method for filling containers, said method substantially as herein described with reference to any one of the embodiments of the invention shown in the accompanying drawings. Dated 30 March, 2004 Alcoa Deutschland GmbH Patent Attorneys for the Applicant/Nominated Person SPRUSON FERGUSON oo* [R:\LIBLL] 14757spcci.doc:kch
AU12703/01A 1999-09-07 2000-09-04 Device and method for filling containers in a sterile manner Ceased AU773303B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE29923540 1999-09-07
DE29923540 1999-09-07
DE10041319 2000-08-23
DE10041319A DE10041319A1 (en) 1999-09-07 2000-08-23 Device and method for filling containers
PCT/EP2000/008614 WO2001017891A1 (en) 1999-09-07 2000-09-04 Device and method for filling containers in a sterile manner

Publications (2)

Publication Number Publication Date
AU1270301A AU1270301A (en) 2001-04-10
AU773303B2 true AU773303B2 (en) 2004-05-20

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Family Applications (1)

Application Number Title Priority Date Filing Date
AU12703/01A Ceased AU773303B2 (en) 1999-09-07 2000-09-04 Device and method for filling containers in a sterile manner

Country Status (21)

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EP (1) EP1230144B1 (en)
JP (1) JP2003524560A (en)
CN (1) CN1177753C (en)
AT (1) ATE261908T1 (en)
AU (1) AU773303B2 (en)
BR (1) BR0013859A (en)
CA (1) CA2384347A1 (en)
CZ (1) CZ2002848A3 (en)
DK (1) DK1230144T3 (en)
EA (1) EA003683B1 (en)
EE (1) EE04543B1 (en)
ES (1) ES2215745T3 (en)
HK (1) HK1050884A1 (en)
HU (1) HUP0202580A3 (en)
IL (1) IL148519A0 (en)
MX (1) MXPA02002473A (en)
NO (1) NO20021112L (en)
PL (1) PL354780A1 (en)
PT (1) PT1230144E (en)
TR (1) TR200200596T2 (en)
WO (1) WO2001017891A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10140807A1 (en) * 2001-08-15 2003-02-27 Ruediger Haaga Gmbh Machine system for sterilizing and filling containers
JP4889000B2 (en) * 2005-12-27 2012-02-29 三菱重工食品包装機械株式会社 Sterilizer
DE102007003835A1 (en) 2007-01-25 2008-07-31 Fresenius Medical Care Deutschland Gmbh Closure for filling and closing of containers containing medical liquid and method for filling a container with a medical liquid and sealing the container
DE102008023797A1 (en) 2008-05-15 2009-11-19 Krones Ag Device for sterilizing container closures
EP2279830A1 (en) * 2009-07-28 2011-02-02 Linde Aktiengesellschaft Method for removing transport labels
JP2012017137A (en) * 2010-07-09 2012-01-26 Astech Engineering:Kk Container processing apparatus
CN104512581A (en) * 2013-09-30 2015-04-15 山东工大机械有限公司 Intelligent aseptic packaging production line

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4018142A1 (en) * 1990-06-06 1991-12-12 Hermann Kronseder Method for filling bottles with beverages - involves microwave radiation of bottles prior to filling
EP0893397A1 (en) * 1997-07-24 1999-01-27 Krones Ag Process and apparatus for filling bottles under sterile conditions
WO1999008933A1 (en) * 1997-08-15 1999-02-25 Tetra Laval Holdings & Finance, S.A. Bottle sterilization method and apparatus

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DE4407183A1 (en) * 1994-03-04 1995-09-07 Bernd Uhlig Batch UV-sterilisation enables re-use of used containers
IT1279846B1 (en) * 1995-08-11 1997-12-18 Rossi & Catelli Spa CONTINUOUS ASEPTIC BOTTLING SYSTEM
EP0951437B1 (en) * 1997-01-07 2001-04-04 GEA Finnah GmbH Method and machine for preparing bottles for filling, and method of filling bottles
DE19806520A1 (en) * 1998-02-17 1999-08-19 Ruediger Haaga Gmbh Process for sterilization, filling and sealing of product container using low pressure plasma as sterilizing agent

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4018142A1 (en) * 1990-06-06 1991-12-12 Hermann Kronseder Method for filling bottles with beverages - involves microwave radiation of bottles prior to filling
EP0893397A1 (en) * 1997-07-24 1999-01-27 Krones Ag Process and apparatus for filling bottles under sterile conditions
WO1999008933A1 (en) * 1997-08-15 1999-02-25 Tetra Laval Holdings & Finance, S.A. Bottle sterilization method and apparatus

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Publication number Publication date
CN1372526A (en) 2002-10-02
CA2384347A1 (en) 2001-03-15
NO20021112L (en) 2002-05-03
CN1177753C (en) 2004-12-01
PT1230144E (en) 2004-08-31
HK1050884A1 (en) 2003-07-11
HUP0202580A3 (en) 2002-12-28
MXPA02002473A (en) 2005-03-31
EE04543B1 (en) 2005-10-17
WO2001017891A1 (en) 2001-03-15
DK1230144T3 (en) 2004-07-26
EP1230144A1 (en) 2002-08-14
EA003683B1 (en) 2003-08-28
BR0013859A (en) 2002-05-14
EE200200125A (en) 2003-06-16
PL354780A1 (en) 2004-02-23
TR200200596T2 (en) 2002-09-23
EP1230144B1 (en) 2004-03-17
CZ2002848A3 (en) 2002-10-16
NO20021112D0 (en) 2002-03-06
IL148519A0 (en) 2002-09-12
EA200200345A1 (en) 2002-08-29
ES2215745T3 (en) 2004-10-16
HUP0202580A2 (en) 2002-11-28
JP2003524560A (en) 2003-08-19
ATE261908T1 (en) 2004-04-15
AU1270301A (en) 2001-04-10

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