AU7624498A - Process for making gamma-methylene-10-deazaaminopterin (MDAM) - Google Patents

Process for making gamma-methylene-10-deazaaminopterin (MDAM)

Info

Publication number
AU7624498A
AU7624498A AU76244/98A AU7624498A AU7624498A AU 7624498 A AU7624498 A AU 7624498A AU 76244/98 A AU76244/98 A AU 76244/98A AU 7624498 A AU7624498 A AU 7624498A AU 7624498 A AU7624498 A AU 7624498A
Authority
AU
Australia
Prior art keywords
mdam
deazaaminopterin
methylene
making gamma
gamma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU76244/98A
Inventor
Frederick Hausheer
Dasharatha Gauravaram Reddy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BioNumerik Pharmaceuticals Inc
Original Assignee
BioNumerik Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BioNumerik Pharmaceuticals Inc filed Critical BioNumerik Pharmaceuticals Inc
Publication of AU7624498A publication Critical patent/AU7624498A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU76244/98A 1996-12-02 1997-12-02 Process for making gamma-methylene-10-deazaaminopterin (MDAM) Abandoned AU7624498A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3225096P 1996-12-02 1996-12-02
US60/032250 1996-12-02
PCT/US1997/021743 WO1998024789A1 (en) 1996-12-02 1997-12-02 PROCESS FOR MAKING η-METHYLENE-10-DEAZAAMINOPTERIN (MDAM)

Publications (1)

Publication Number Publication Date
AU7624498A true AU7624498A (en) 1998-06-29

Family

ID=21863917

Family Applications (1)

Application Number Title Priority Date Filing Date
AU76244/98A Abandoned AU7624498A (en) 1996-12-02 1997-12-02 Process for making gamma-methylene-10-deazaaminopterin (MDAM)

Country Status (2)

Country Link
AU (1) AU7624498A (en)
WO (1) WO1998024789A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102952137A (en) * 2012-10-08 2013-03-06 天津科创医药中间体技术生产力促进有限公司 Preparation method of 2,4-diamino-6-bromomethyl pteridine
AU2022425491A1 (en) 2021-12-30 2024-07-04 Byondis B.V. Antifolate linker-drugs and antibody-drug conjugates

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4393064A (en) * 1976-03-05 1983-07-12 Sri International Process and composition for treatment of leukemia and process for preparing the same
US4753939A (en) * 1976-03-05 1988-06-28 Sri International Process and composition for treatment of luekemia and process for preparing the same
US4684653A (en) * 1985-03-08 1987-08-04 The Trustees Of Princeton University Pyrido(2,3-d)pyrimidine derivatives
US4996207A (en) * 1990-01-18 1991-02-26 Nair Madhavan G Three new non-polyglutamatable deazaaminopterins
US5073554A (en) * 1990-01-18 1991-12-17 Nair Madhavan G Two non-polyglutamatable antifolates
US5374726A (en) * 1992-03-03 1994-12-20 Degraw; Joseph I. Process for preparing 10-deazaaminopterins and 5,10-and 8,10-dideazaaminopterins from pteroic dicarboxylic acid diesters
US5550128A (en) * 1994-09-09 1996-08-27 Nair; Madhavan G. Enantiomers of gamma methylene 10-deaza aminopterin and process for preparing the same

Also Published As

Publication number Publication date
WO1998024789A1 (en) 1998-06-11

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