AU752041B2 - Methods for treatment and prevention of infections - Google Patents

Methods for treatment and prevention of infections Download PDF

Info

Publication number
AU752041B2
AU752041B2 AU34790/99A AU3479099A AU752041B2 AU 752041 B2 AU752041 B2 AU 752041B2 AU 34790/99 A AU34790/99 A AU 34790/99A AU 3479099 A AU3479099 A AU 3479099A AU 752041 B2 AU752041 B2 AU 752041B2
Authority
AU
Australia
Prior art keywords
seq
sequence
active agent
group
tyr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU34790/99A
Other languages
English (en)
Other versions
AU3479099A (en
Inventor
Gere Dizerega
Kathleen E Rodgers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Southern California USC
Original Assignee
University of Southern California USC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Southern California USC filed Critical University of Southern California USC
Publication of AU3479099A publication Critical patent/AU3479099A/en
Application granted granted Critical
Publication of AU752041B2 publication Critical patent/AU752041B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0819Tripeptides with the first amino acid being acidic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/085Angiotensins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0821Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1005Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1021Tetrapeptides with the first amino acid being acidic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/14Angiotensins: Related peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/32Angiotensins [AT], angiotensinogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU34790/99A 1998-04-09 1999-04-07 Methods for treatment and prevention of infections Ceased AU752041B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US8126298P 1998-04-09 1998-04-09
US60/081262 1998-04-09
US8902498P 1998-06-12 1998-06-12
US60/089024 1998-06-12
PCT/US1999/007654 WO1999052540A1 (en) 1998-04-09 1999-04-07 Methods for treatment and prevention of infections

Publications (2)

Publication Number Publication Date
AU3479099A AU3479099A (en) 1999-11-01
AU752041B2 true AU752041B2 (en) 2002-09-05

Family

ID=26765405

Family Applications (1)

Application Number Title Priority Date Filing Date
AU34790/99A Ceased AU752041B2 (en) 1998-04-09 1999-04-07 Methods for treatment and prevention of infections

Country Status (5)

Country Link
EP (1) EP1067952A1 (ja)
JP (1) JP2002511416A (ja)
AU (1) AU752041B2 (ja)
CA (1) CA2324988A1 (ja)
WO (1) WO1999052540A1 (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6730775B1 (en) 1999-03-23 2004-05-04 University Of Southern California Methods for limiting scar and adhesion formation
CA2449150C (en) 2001-05-31 2011-07-12 Vicore Pharma Ab Tricyclic compounds useful as angiotensin ii agonists
CA2448051A1 (en) * 2001-06-04 2002-12-12 Human Genome Sciences, Inc. Methods and compositions for modulating ace-2 activity
WO2002098448A1 (en) 2001-06-04 2002-12-12 Human Genome Sciences, Inc. Methods and compositions for modulating ace-2 activity
US20090227507A1 (en) * 2008-03-10 2009-09-10 University Of Southern California Angiotensin (1-7) Dosage Forms and Uses Thereof
EP2603228A1 (en) * 2010-08-10 2013-06-19 The University Of Southern California Use of angiotensin- ii (1-7) in cell transplantation and as an agent for preventing/treating norovirus infection
EP2455388A1 (en) 2010-11-23 2012-05-23 LanthioPep B.V. Novel angiotensin type 2 (AT2) receptor agonists and uses thereof.
US8557958B1 (en) 2012-06-18 2013-10-15 Tarix Pharmaceuticals Ltd. Compositions and methods for treatment of diabetes
US8633158B1 (en) 2012-10-02 2014-01-21 Tarix Pharmaceuticals Ltd. Angiotensin in treating brain conditions
US9333233B2 (en) 2014-02-25 2016-05-10 Tarix Pharmaceuticals Ltd. Methods and compositions for the delayed treatment of stroke
WO2021023698A1 (en) 2019-08-02 2021-02-11 Lanthiopep B.V Angiotensin type 2 (at2) receptor agonists for use in the treatment of cancer

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5015629A (en) * 1989-06-26 1991-05-14 University Of Southern California Tissue repair
AU7730294A (en) * 1993-09-24 1995-04-10 University Of Southern California Use of angiotensin iii and analogs thereof in tissue repair

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5015629A (en) * 1989-06-26 1991-05-14 University Of Southern California Tissue repair
AU7730294A (en) * 1993-09-24 1995-04-10 University Of Southern California Use of angiotensin iii and analogs thereof in tissue repair

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
WRAY ET AL, LANCET (1995) DEC 16 P 346 *

Also Published As

Publication number Publication date
JP2002511416A (ja) 2002-04-16
EP1067952A1 (en) 2001-01-17
AU3479099A (en) 1999-11-01
WO1999052540A1 (en) 1999-10-21
CA2324988A1 (en) 1999-10-21

Similar Documents

Publication Publication Date Title
AU759285B2 (en) Methods to increase white blood cell survival after chemotherapy
EP1333034B1 (en) Use of angiotensin II analogs in tissue repair
US7786085B2 (en) Method for treating a patient undergoing chemotherapy
EP1275396B1 (en) Use of angiotensin II fragments and analogs thereof in tissue repair
AU752041B2 (en) Methods for treatment and prevention of infections
US6821953B1 (en) Methods for treating and preventing damage to mucosal tissue
US20090197799A1 (en) Methods for preparing purified lipotides
US6762167B1 (en) Methods for treating a patient undergoing chemotherapy
US6498238B1 (en) Glycopeptide antibacterial compounds, compositions containing same and methods of using same
ES2267513T3 (es) Angiotensina ii y analogos de la misma para limitar la formacion de cicatrices y de adherencias.
JP4817335B2 (ja) 新規抗菌性ペプチド
EP1239867B1 (en) Methods for treating and preventing damage to mucosal tissue
US20080255055A1 (en) Use of Derivatives of Dipeptides for the Manufacture of of a Medicament for the Treamtent of Microbial Infections
WO2001055176A2 (en) Methods for inhibiting smooth muscle cell proliferation
MXPA00009896A (en) Methods for treatment and prevention of infections
WO1997048725A1 (en) Novel peptides for prevention and treatment of infection
US7449545B2 (en) Antimicrobial bolisin peptides
MXPA00011112A (en) Methods to increase white blood cell survival after chemotherapy
Śleszyńska et al. receptor antagonists—influence of C-terminal segment modifications on their pharmacological properties

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)