AU7468081A - 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthy-ridine- 3-carboxylic acids - Google Patents

7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthy-ridine- 3-carboxylic acids

Info

Publication number
AU7468081A
AU7468081A AU74680/81A AU7468081A AU7468081A AU 7468081 A AU7468081 A AU 7468081A AU 74680/81 A AU74680/81 A AU 74680/81A AU 7468081 A AU7468081 A AU 7468081A AU 7468081 A AU7468081 A AU 7468081A
Authority
AU
Australia
Prior art keywords
naphthy
ridine
cyclopropyl
dihydro
oxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU74680/81A
Other versions
AU540242B2 (en
Inventor
Klaus Grohe
Karl Georg Metzger
Hans-Joachim Zeiler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6111041&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU7468081(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer AG filed Critical Bayer AG
Publication of AU7468081A publication Critical patent/AU7468081A/en
Application granted granted Critical
Publication of AU540242B2 publication Critical patent/AU540242B2/en
Adjusted expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fodder In General (AREA)
  • Quinoline Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
AU74680/81A 1980-09-03 1981-08-27 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthy-ridine- 3-carboxylic acids Expired AU540242B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE30331578 1980-09-03
DE19803033157 DE3033157A1 (en) 1980-09-03 1980-09-03 7-AMINO-1-CYCLOPROPYL-4-OXO-1,4-DIHYDRO-NAPHTHYRIDINE-3-CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE ANTIBACTERIAL AGENTS CONTAINING THEM

Publications (2)

Publication Number Publication Date
AU7468081A true AU7468081A (en) 1982-03-11
AU540242B2 AU540242B2 (en) 1984-11-08

Family

ID=6111041

Family Applications (1)

Application Number Title Priority Date Filing Date
AU74680/81A Expired AU540242B2 (en) 1980-09-03 1981-08-27 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthy-ridine- 3-carboxylic acids

Country Status (17)

Country Link
EP (1) EP0049355B1 (en)
JP (3) JPS5777683A (en)
KR (1) KR870000441B1 (en)
AR (1) AR227063A1 (en)
AT (1) ATE9803T1 (en)
AU (1) AU540242B2 (en)
CY (1) CY1301A (en)
DE (2) DE3033157A1 (en)
DK (1) DK161460C (en)
ES (1) ES505138A0 (en)
HK (1) HK61485A (en)
IE (1) IE51541B1 (en)
KE (1) KE3545A (en)
MY (1) MY8700363A (en)
NL (2) NL930033I1 (en)
SG (1) SG44685G (en)
ZA (1) ZA816080B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU573126B2 (en) * 1981-10-29 1988-05-26 Bayer Aktiengesellschaft 1,4-dihydro-4-oxoquinoline-3-carboxylic acids

Families Citing this family (63)

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JPS5925391A (en) * 1982-07-30 1984-02-09 Dainippon Pharmaceut Co Ltd Pyridylnaphthyridine derivative and salt thereof
US5281612A (en) * 1982-09-09 1994-01-25 Warner-Lambert Company Naphthyridine antibacterial agents
US4665079A (en) * 1984-02-17 1987-05-12 Warner-Lambert Company Antibacterial agents
DE3248506A1 (en) * 1982-12-29 1984-07-05 Bayer Ag, 5090 Leverkusen 1-CYCLOPROPYL-6-FLUOR-1,4-DIHYDRO-4-OXO-7 (ALKYL-1-PIPERAZINYL) -3-CHINOLINE CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR CONTAINING ANTIBACTERIAL AGENTS
DE3248507A1 (en) * 1982-12-29 1984-07-05 Bayer Ag, 5090 Leverkusen MICROBICIDE AGENTS BASED ON CHINOLONIC CARBONIC ACID
DE3248505A1 (en) * 1982-12-29 1984-07-05 Bayer Ag, 5090 Leverkusen 1-CYCLOPROPYL-6-FLUOR-1,4-DIHYDRO-4-OXO-7 (4- (OXOALKYL) -1-PIPERAZINYL / -3-QUINOLINE CARBONIC ACIDS AND THEIR DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND THEIR CONTAINERS
DE3306771A1 (en) * 1983-02-25 1984-08-30 Bayer Ag, 5090 Leverkusen CHINOLONIC CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE ANTIBACTERIAL AGENTS CONTAINING THEM
DE3306772A1 (en) * 1983-02-25 1984-08-30 Bayer Ag, 5090 Leverkusen CHINOLONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE ANTIBACTERIAL AGENTS CONTAINING THEM
DE3308909A1 (en) * 1983-03-12 1984-09-13 Bayer Ag, 5090 Leverkusen BACTERICIDALS BASED ON CHINOLONIC CARBONIC ACID
DE3308908A1 (en) * 1983-03-12 1984-09-13 Bayer Ag, 5090 Leverkusen BACTERICIDAL AGENTS
DE3318145A1 (en) * 1983-05-18 1984-11-22 Bayer Ag, 5090 Leverkusen 7-AMINO-1-CYCLOPROPYL-6,8-DIFLUOR-1,4-DIHYDRO-4-OXO-3-CHINOLINE CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR CONTAINING ANTIBACTERIAL AGENTS
JPS6056959A (en) * 1983-07-18 1985-04-02 アボツト　ラボラトリ−ズ Quinoline antifungal compound
DE3326190A1 (en) * 1983-07-20 1985-01-31 Bayer Ag, 5090 Leverkusen 5-CYCLOPROPYL-5,8-DIHYDRO-8-OXO-1,3-DIOXOLO- (4,5-G) QUINOLINE-7-CARBONIC ACID, METHOD FOR THE PRODUCTION THEREOF AND THEIR ANTIBACTERIAL AGENTS CONTAINING THEM
JPS6028978A (en) * 1983-07-27 1985-02-14 Dainippon Pharmaceut Co Ltd 1,8-naphthyridine derivative
CS274601B2 (en) 1983-07-27 1991-09-15 Dainippon Pharmaceutical Co Method of 1,8-naphthyridine derivative production
JPS60260577A (en) * 1984-06-06 1985-12-23 Dainippon Pharmaceut Co Ltd 1,8-naphthyridine derivative
JPS6032790A (en) * 1983-08-01 1985-02-19 Dainippon Pharmaceut Co Ltd 1,8-naphthyridines
AU553415B2 (en) * 1983-09-19 1986-07-17 Abbott Japan Co., Ltd. 6-fluoro-1-4-dihydro-4-oxo-7-substituted piperazinyl- quinoline-3-carboxylic acids
JPS6089480A (en) * 1983-10-21 1985-05-20 Dainippon Pharmaceut Co Ltd Pyridonecarboxylic acid derivative
US4551456A (en) * 1983-11-14 1985-11-05 Merck & Co., Inc. Ophthalmic use of norfloxacin and related antibiotics
JPS60126284A (en) * 1983-12-09 1985-07-05 Dainippon Pharmaceut Co Ltd Pyridonecarboxylic acid derivative and salt thereof
EP0160578B1 (en) * 1984-02-17 1989-11-23 Daiichi Seiyaku Co., Ltd. 1,8-naphthyridine derivatives
IL74244A (en) * 1984-02-17 1988-06-30 Warner Lambert Co Quinoline derivatives,their preparation and pharmaceutical compositions containing them
JPS60228479A (en) * 1984-04-26 1985-11-13 Toyama Chem Co Ltd 1,4-dihydro-4-oxonaphthyridine derivative and salt thereof
US4732311A (en) * 1984-05-31 1988-03-22 Nippondenso Co., Ltd. Process of producing lightweight and corrosion-resistant heat exchanger
US5468861A (en) * 1984-06-04 1995-11-21 Bayer Aktiengesellschaft 8-chloro-1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid and alkyl esters thereof
DE3420770A1 (en) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 1-CYCLOPROPYL-6-FLUOR-1,4-DIHYDRO-4-OXO-7- (3-OXO-1-PIPERAZINYL) -3-CHINOLONIC CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR CONTAINING ANTIBACTERIAL AGENTS
DE3420743A1 (en) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-AMINO-1-CYCLOPROPYL-6,8-DIHALOGEN-1,4-DIHYDRO-4-OXO-3-CHINOLINE CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR CONTAINING ANTIBACTERIAL AGENTS
DE3420798A1 (en) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7- (3-ARYL-L-PIPERAZINYL) - AND 7- (3-CYCLOHEXYL-L-PIPERAZINYL) -3-CHINOLONIC CARBONIC ACIDS
IE58742B1 (en) * 1984-07-20 1993-11-05 Warner Lambert Co Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
JPS61118370A (en) * 1985-10-30 1986-06-05 Kyorin Pharmaceut Co Ltd Quinolonecarboxylic acid and its preparation
IN162769B (en) * 1984-11-13 1988-07-09 Kyorin Seiyaku Kk
JPS61180771A (en) * 1985-01-05 1986-08-13 バイエル・アクチエンゲゼルシヤフト Basic prescription of quinolone carboxylic acid
DE3517709A1 (en) * 1985-01-05 1986-07-10 Bayer Ag BASIC PREPARATIONS OF CHINOLON CARBON ACIDS
DE3508816A1 (en) * 1985-01-10 1986-07-10 Bayer Ag, 5090 Leverkusen 6,7-DISUBSTITUTED 1-CYCLOPROPYL-1,4-DIHYDRO-4-OXO-1,8-NAPHTYRIDINE-3-CARBONIC ACIDS
DE3504643A1 (en) * 1985-02-12 1986-08-14 Bayer Ag, 5090 Leverkusen 1-CYCLOPROPYL-1,4-DIHYDRO-4-OXO-7- (4- (2-OXO-1,3-DIOXOL-4-YL-METHYL) -1-PIPERAZINYL) -3-QUINOLINE CARBONIC ACIDS, METHOD FOR YOURSELF PRODUCTION AND THIS ANTIBACTERIAL AGENT
DE3509546A1 (en) * 1985-03-16 1986-09-25 Bayer Ag, 5090 Leverkusen 7-AMINO-1- (SUBST.CYCLOPROPYL) -1,4-DIHYDRO-4-OXO-3-CHINOLINE CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE ANTIBACTERIAL AGENTS CONTAINING THEM
IT1200470B (en) * 1985-05-10 1989-01-18 Schering Spa ANTIBACTERIAL ACTIVITY COMPOUNDS, THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS
GB8512143D0 (en) * 1985-05-14 1985-06-19 Beecham Group Plc Method of treatment
DE3519286A1 (en) * 1985-05-30 1986-12-04 Bayer Ag, 5090 Leverkusen 7-AZOLYL-1-CYCLOPROPYL-1,4-DIHYDRO-4-OXO-3-CHINOLINE CARBONIC ACIDS AND -1,8-NAPHTHYRIDINE-3-CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR ANTIBACTERS CONTAINING THEM
DE3608745A1 (en) * 1985-07-24 1987-01-29 Bayer Ag BACTERICIDAL PREPARATIONS FOR APPLICATION IN THE VETERINE MEDICINE AREA
AU594983B2 (en) * 1985-10-29 1990-03-22 Dainippon Pharmaceutical Co. Ltd. Novel quinoline derivatives and processes for preparation thereof
EP0224121A3 (en) * 1985-11-19 1987-11-11 ROTTAPHARM S.p.A. 7-[4-amino-piperazinyl]- or 7-[4-chloro-piperazinyl]quinolinone derivatives, a process for the preparation thereof and pharmaceutical compositions containing them
DE3542002A1 (en) * 1985-11-28 1987-06-04 Bayer Ag 1-CYCLOPROPYL-6-FLUOR-1,4-DIHYDRO-4-OXO-7- (1-PIPERAZINYL) -3-QUINOLINE CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR ANTIBACTERIAL AGENTS CONTAINING THEM
US4668680A (en) * 1985-12-12 1987-05-26 Warner-Lambert Company 5-amino-6,8-difluoroquinolones as antibacterial agents
DE3601566A1 (en) * 1986-01-21 1987-07-23 Bayer Ag PHARMACEUTICAL PREPARATIONS OF CIPROFLOXACIN
US5286754A (en) * 1986-01-21 1994-02-15 Bayer Aktiengesellschaft Pharmaceutical formulations of ciprofloxacin
US4692454A (en) * 1986-02-03 1987-09-08 Warner-Lambert Company Opthalmic use of quinolone antibiotics
DE3705621C2 (en) * 1986-02-25 1997-01-09 Otsuka Pharma Co Ltd Heterocyclic substituted quinolonecarboxylic acid derivatives
HU198709B (en) * 1987-04-08 1989-11-28 Chinoin Gyogyszer Es Vegyeszet Process for producing quinoline-carboxylic acid derivatives
DE3713672A1 (en) * 1987-04-24 1988-11-17 Bayer Ag METHOD FOR PRODUCING PARENTERALLY AVAILABLE CHINOLONIC CARBONIC ACIDS
DE3719764A1 (en) * 1987-06-13 1988-12-22 Bayer Ag ION EXCHANGE RESINS LOADED WITH CHINOLON CARBONIC ACID DERIVATIVES, THEIR PRODUCTION AND USE
DE3902079A1 (en) * 1988-04-15 1989-10-26 Bayer Ag IN THE. INJECTION FORMS OF GYRASE INHIBITORS
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU573126B2 (en) * 1981-10-29 1988-05-26 Bayer Aktiengesellschaft 1,4-dihydro-4-oxoquinoline-3-carboxylic acids

Also Published As

Publication number Publication date
DE3166619D1 (en) 1984-11-15
DE3033157A1 (en) 1982-04-01
NL930032I1 (en) 1993-08-02
KR830007642A (en) 1983-11-04
ZA816080B (en) 1982-08-25
JPH0316344B2 (en) 1991-03-05
DK387781A (en) 1982-03-04
ES8206523A1 (en) 1982-08-16
JPH0314811B2 (en) 1991-02-27
AU540242B2 (en) 1984-11-08
NL930032I2 (en) 1997-03-03
IE51541B1 (en) 1987-01-07
KR870000441B1 (en) 1987-03-10
CY1301A (en) 1985-12-06
ATE9803T1 (en) 1984-10-15
JPS6356224B2 (en) 1988-11-07
KE3545A (en) 1985-07-19
HK61485A (en) 1985-08-23
JPS62161763A (en) 1987-07-17
AR227063A1 (en) 1982-09-15
SG44685G (en) 1986-01-17
JPS62161728A (en) 1987-07-17
EP0049355A1 (en) 1982-04-14
DK161460C (en) 1991-12-16
DK161460B (en) 1991-07-08
NL930033I1 (en) 1993-08-02
ES505138A0 (en) 1982-08-16
MY8700363A (en) 1987-12-31
IE812032L (en) 1982-03-03
EP0049355B1 (en) 1984-10-10
JPS5777683A (en) 1982-05-15

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Legal Events

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MK14 Patent ceased section 143(a) (annual fees not paid) or expired