AU744279B2 - Protein delivery by secretory gland expression - Google Patents

Protein delivery by secretory gland expression Download PDF

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Publication number
AU744279B2
AU744279B2 AU96689/98A AU9668998A AU744279B2 AU 744279 B2 AU744279 B2 AU 744279B2 AU 96689/98 A AU96689/98 A AU 96689/98A AU 9668998 A AU9668998 A AU 9668998A AU 744279 B2 AU744279 B2 AU 744279B2
Authority
AU
Australia
Prior art keywords
dna
polypeptide
interest
pancreas
interferon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU96689/98A
Other languages
English (en)
Other versions
AU9668998A (en
Inventor
Michael S. German
Ira D Goldfine
Stephen S. Rothman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/942,939 external-priority patent/US6004944A/en
Application filed by University of California filed Critical University of California
Publication of AU9668998A publication Critical patent/AU9668998A/en
Application granted granted Critical
Publication of AU744279B2 publication Critical patent/AU744279B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/27Growth hormone [GH], i.e. somatotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU96689/98A 1997-10-02 1998-09-24 Protein delivery by secretory gland expression Ceased AU744279B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/942,939 US6004944A (en) 1995-03-24 1997-10-02 Protein delivery by secretory gland expression
US08/942939 1997-10-02
PCT/US1998/020199 WO1999017610A1 (fr) 1997-10-02 1998-09-24 Administration de proteines par l'expression des glandes secretoires

Publications (2)

Publication Number Publication Date
AU9668998A AU9668998A (en) 1999-04-27
AU744279B2 true AU744279B2 (en) 2002-02-21

Family

ID=25478850

Family Applications (1)

Application Number Title Priority Date Filing Date
AU96689/98A Ceased AU744279B2 (en) 1997-10-02 1998-09-24 Protein delivery by secretory gland expression

Country Status (5)

Country Link
EP (1) EP1030557A4 (fr)
JP (1) JP2001518316A (fr)
AU (1) AU744279B2 (fr)
CA (1) CA2304803A1 (fr)
WO (1) WO1999017610A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6531455B1 (en) 1995-03-24 2003-03-11 The Regents Of The University Of California Delivery of polynucleotides by secretory gland expression
EP1170994A1 (fr) * 1999-04-23 2002-01-16 University Of Guelph Animaux transgeniques exprimant des proteines salivaires
US7115795B1 (en) 1999-04-23 2006-10-03 University Of Guelph Transgenic animals expressing salivary proteins
US9171343B1 (en) 2012-09-11 2015-10-27 Aseko, Inc. Means and method for improved glycemic control for diabetic patients
US9897565B1 (en) 2012-09-11 2018-02-20 Aseko, Inc. System and method for optimizing insulin dosages for diabetic subjects
US9898585B2 (en) 2014-01-31 2018-02-20 Aseko, Inc. Method and system for insulin management
US9486580B2 (en) 2014-01-31 2016-11-08 Aseko, Inc. Insulin management
US11081226B2 (en) 2014-10-27 2021-08-03 Aseko, Inc. Method and controller for administering recommended insulin dosages to a patient
JP6989262B2 (ja) 2014-10-27 2022-01-05 アセコー インコーポレイテッド 皮下外来患者管理
WO2017031440A1 (fr) 2015-08-20 2017-02-23 Aseko, Inc. Conseiller de thérapie pour la gestion du diabète

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5792751A (en) * 1992-04-13 1998-08-11 Baylor College Of Medicine Tranformation of cells associated with fluid spaces
US5885971A (en) * 1995-03-24 1999-03-23 The Regents Of The University Of California Gene therapy by secretory gland expression

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ADESANYA MR ET AL (1996) HUMAN GENE THERAPY 7:1085-1093 *
KAGAMI H ET AL (1996) HUMAN GENE THERAPY 7:2177-2184 *

Also Published As

Publication number Publication date
WO1999017610A1 (fr) 1999-04-15
EP1030557A4 (fr) 2002-07-31
CA2304803A1 (fr) 1999-04-15
JP2001518316A (ja) 2001-10-16
AU9668998A (en) 1999-04-27
EP1030557A1 (fr) 2000-08-30

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Publication Publication Date Title
US6004944A (en) Protein delivery by secretory gland expression
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US5837693A (en) Intravenous hormone polypeptide delivery by salivary gland expression
US20120142760A1 (en) Compositions and methods for regulated protein expression in gut
AU744279B2 (en) Protein delivery by secretory gland expression
US6531455B1 (en) Delivery of polynucleotides by secretory gland expression
Mackay Delivery of recombinant peptide and protein drugs
US20050026859A1 (en) Methods and compositions of gene delivery agents for systemic and local therapy

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired