AU738348B2 - Platelet suspensions and methods for resuspending platelets - Google Patents
Platelet suspensions and methods for resuspending platelets Download PDFInfo
- Publication number
- AU738348B2 AU738348B2 AU73896/98A AU7389698A AU738348B2 AU 738348 B2 AU738348 B2 AU 738348B2 AU 73896/98 A AU73896/98 A AU 73896/98A AU 7389698 A AU7389698 A AU 7389698A AU 738348 B2 AU738348 B2 AU 738348B2
- Authority
- AU
- Australia
- Prior art keywords
- platelet
- platelets
- plasma
- accordance
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title claims description 27
- 239000000725 suspension Substances 0.000 title claims description 21
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 52
- 239000003634 thrombocyte concentrate Substances 0.000 claims description 44
- 210000002381 plasma Anatomy 0.000 claims description 43
- 235000002639 sodium chloride Nutrition 0.000 claims description 27
- 239000011780 sodium chloride Substances 0.000 claims description 26
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims description 20
- 210000004623 platelet-rich plasma Anatomy 0.000 claims description 12
- 239000001103 potassium chloride Substances 0.000 claims description 10
- 235000011164 potassium chloride Nutrition 0.000 claims description 10
- 235000015097 nutrients Nutrition 0.000 claims description 5
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 claims description 3
- 150000003841 chloride salts Chemical class 0.000 claims description 3
- 239000001632 sodium acetate Substances 0.000 claims description 3
- 235000017281 sodium acetate Nutrition 0.000 claims description 3
- 239000001509 sodium citrate Substances 0.000 claims description 3
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 3
- 210000001772 blood platelet Anatomy 0.000 description 97
- 239000000243 solution Substances 0.000 description 26
- 210000004369 blood Anatomy 0.000 description 16
- 239000008280 blood Substances 0.000 description 16
- 239000000306 component Substances 0.000 description 10
- 239000012266 salt solution Substances 0.000 description 10
- 239000012085 test solution Substances 0.000 description 8
- 238000000926 separation method Methods 0.000 description 7
- XSDQTOBWRPYKKA-UHFFFAOYSA-N amiloride Chemical compound NC(=N)NC(=O)C1=NC(Cl)=C(N)N=C1N XSDQTOBWRPYKKA-UHFFFAOYSA-N 0.000 description 6
- 229960002576 amiloride Drugs 0.000 description 6
- 210000004027 cell Anatomy 0.000 description 6
- 239000008188 pellet Substances 0.000 description 5
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 description 4
- 210000003743 erythrocyte Anatomy 0.000 description 4
- 210000000265 leukocyte Anatomy 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 3
- 239000000654 additive Substances 0.000 description 3
- 230000000996 additive effect Effects 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- 108091006629 SLC13A2 Proteins 0.000 description 2
- 238000002835 absorbance Methods 0.000 description 2
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 description 2
- 210000000601 blood cell Anatomy 0.000 description 2
- 230000001413 cellular effect Effects 0.000 description 2
- 239000000470 constituent Substances 0.000 description 2
- 239000000819 hypertonic solution Substances 0.000 description 2
- 229940021223 hypertonic solution Drugs 0.000 description 2
- 229910001629 magnesium chloride Inorganic materials 0.000 description 2
- 230000003204 osmotic effect Effects 0.000 description 2
- 235000011083 sodium citrates Nutrition 0.000 description 2
- 238000009987 spinning Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 239000005528 B01AC05 - Ticlopidine Substances 0.000 description 1
- 239000002126 C01EB10 - Adenosine Substances 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 229960005305 adenosine Drugs 0.000 description 1
- 239000012503 blood component Substances 0.000 description 1
- -1 but not limited to Substances 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 229940061607 dibasic sodium phosphate Drugs 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 description 1
- XEYBHCRIKKKOSS-UHFFFAOYSA-N disodium;azanylidyneoxidanium;iron(2+);pentacyanide Chemical compound [Na+].[Na+].[Fe+2].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].[O+]#N XEYBHCRIKKKOSS-UHFFFAOYSA-N 0.000 description 1
- 239000012636 effector Substances 0.000 description 1
- 230000005714 functional activity Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 239000000644 isotonic solution Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 229940045641 monobasic sodium phosphate Drugs 0.000 description 1
- 229910000403 monosodium phosphate Inorganic materials 0.000 description 1
- 235000019799 monosodium phosphate Nutrition 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 235000021317 phosphate Nutrition 0.000 description 1
- 239000002953 phosphate buffered saline Substances 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 229960004249 sodium acetate Drugs 0.000 description 1
- 229960002668 sodium chloride Drugs 0.000 description 1
- 229960001790 sodium citrate Drugs 0.000 description 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- 229940083618 sodium nitroprusside Drugs 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- PHWBOXQYWZNQIN-UHFFFAOYSA-N ticlopidine Chemical compound ClC1=CC=CC=C1CN1CC(C=CS2)=C2CC1 PHWBOXQYWZNQIN-UHFFFAOYSA-N 0.000 description 1
- 229960005001 ticlopidine Drugs 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/871,115 US6063624A (en) | 1997-06-09 | 1997-06-09 | Platelet suspensions and methods for resuspending platelets |
| US08/871115 | 1997-06-09 | ||
| PCT/US1998/010029 WO1998056247A1 (en) | 1997-06-09 | 1998-05-15 | Platelet suspensions and methods for resuspending platelets |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU7389698A AU7389698A (en) | 1998-12-30 |
| AU738348B2 true AU738348B2 (en) | 2001-09-13 |
Family
ID=25356764
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU73896/98A Expired AU738348B2 (en) | 1997-06-09 | 1998-05-15 | Platelet suspensions and methods for resuspending platelets |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US6063624A (https=) |
| EP (1) | EP1001675A4 (https=) |
| JP (1) | JP2002503250A (https=) |
| AU (1) | AU738348B2 (https=) |
| BR (1) | BR9810088A (https=) |
| CA (1) | CA2290389A1 (https=) |
| WO (1) | WO1998056247A1 (https=) |
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6063624A (en) * | 1997-06-09 | 2000-05-16 | Baxter International Inc. | Platelet suspensions and methods for resuspending platelets |
| US7049110B2 (en) | 1998-07-21 | 2006-05-23 | Gambro, Inc. | Inactivation of West Nile virus and malaria using photosensitizers |
| US7498156B2 (en) * | 1998-07-21 | 2009-03-03 | Caridianbct Biotechnologies, Llc | Use of visible light at wavelengths of 500 to 550 nm to reduce the number of pathogens in blood and blood components |
| US7220747B2 (en) | 1999-07-20 | 2007-05-22 | Gambro, Inc. | Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer |
| US7985588B2 (en) | 2000-06-02 | 2011-07-26 | Caridianbct Biotechnologies, Llc | Induction of and maintenance of nucleic acid damage in pathogens using riboflavin and light |
| TW590780B (en) | 2000-06-02 | 2004-06-11 | Gambro Inc | Additive solutions containing riboflavin |
| US7648699B2 (en) | 2000-06-02 | 2010-01-19 | Caridianbct Biotechnologies, Llc | Preventing transfusion related complications in a recipient of a blood transfusion |
| DE60109184T2 (de) * | 2000-10-16 | 2005-12-29 | Universite De Liege | Medizinische zusammensetzung und insbesondere seine verwendung in der flüssigkeitstherapie |
| US6548241B1 (en) * | 2000-11-28 | 2003-04-15 | Gambro, Inc. | Storage solution containing photosensitizer for inactivation of biological contaminants |
| US7011852B2 (en) * | 2001-05-07 | 2006-03-14 | Hemogenesis, Llc | Separation of platelets from whole blood for use as a healant |
| US8101077B2 (en) * | 2001-05-07 | 2012-01-24 | Sivaprasad Sukavaneshvar | Device for separating platelets from fluid suspensions |
| US7264608B2 (en) | 2001-12-05 | 2007-09-04 | Fenwal, Inc. | Manual processing systems and methods for providing blood components conditioned for pathogen inactivation |
| CA2482021C (en) * | 2002-04-24 | 2007-06-19 | Gambro, Inc. | Removal of adenine during a process of pathogen reducing blood and blood components |
| US20030205538A1 (en) | 2002-05-03 | 2003-11-06 | Randel Dorian | Methods and apparatus for isolating platelets from blood |
| US7832566B2 (en) | 2002-05-24 | 2010-11-16 | Biomet Biologics, Llc | Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles |
| US6905612B2 (en) * | 2003-03-21 | 2005-06-14 | Hanuman Llc | Plasma concentrate apparatus and method |
| US7374678B2 (en) | 2002-05-24 | 2008-05-20 | Biomet Biologics, Inc. | Apparatus and method for separating and concentrating fluids containing multiple components |
| US20040182795A1 (en) * | 2003-03-21 | 2004-09-23 | Randel Dorian | Apparatus and method for concentration of plasma from whole blood |
| US7992725B2 (en) | 2002-05-03 | 2011-08-09 | Biomet Biologics, Llc | Buoy suspension fractionation system |
| DE10392686T5 (de) | 2002-05-24 | 2005-07-07 | Biomet Mfg. Corp., Warsaw | Vorrichtung und Verfahren zum Trennen und Konzentrieren von Flüssigkeiten, welche mehrere Komponenten enthalten |
| US7845499B2 (en) | 2002-05-24 | 2010-12-07 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
| US20060278588A1 (en) | 2002-05-24 | 2006-12-14 | Woodell-May Jennifer E | Apparatus and method for separating and concentrating fluids containing multiple components |
| US20080299538A1 (en) * | 2003-02-28 | 2008-12-04 | Caridianbct Biotechnologies, Llc | Pathogen Inactivation of Whole Blood |
| US20070031812A1 (en) * | 2003-06-20 | 2007-02-08 | Pall Corporation | Processing of platelet-containing biological fluids |
| CA2534685A1 (en) * | 2003-08-04 | 2005-02-17 | Human Biosystems | Preservation of blood cells |
| US20050137517A1 (en) * | 2003-12-19 | 2005-06-23 | Baxter International Inc. | Processing systems and methods for providing leukocyte-reduced blood components conditioned for pathogen inactivation |
| US7473678B2 (en) | 2004-10-14 | 2009-01-06 | Biomimetic Therapeutics, Inc. | Platelet-derived growth factor compositions and methods of use thereof |
| US8114841B2 (en) | 2004-10-14 | 2012-02-14 | Biomimetic Therapeutics, Inc. | Maxillofacial bone augmentation using rhPDGF-BB and a biocompatible matrix |
| PL1848473T3 (pl) * | 2005-02-07 | 2013-11-29 | Hanuman Llc | Urządzenie - koncentrator osocza |
| US7694828B2 (en) | 2005-04-27 | 2010-04-13 | Biomet Manufacturing Corp. | Method and apparatus for producing autologous clotting components |
| ES2427993T3 (es) | 2006-02-09 | 2013-11-05 | Biomimetic Therapeutics, Llc | Composiciones y métodos para el tratamiento de hueso |
| US8567609B2 (en) | 2006-05-25 | 2013-10-29 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
| CA2656278C (en) | 2006-06-30 | 2016-02-09 | Biomimetic Therapeutics, Inc. | Compositions and methods for treating rotator cuff injuries |
| US9161967B2 (en) | 2006-06-30 | 2015-10-20 | Biomimetic Therapeutics, Llc | Compositions and methods for treating the vertebral column |
| AU2007203585B2 (en) * | 2006-07-31 | 2013-02-07 | Canadian Blood Services | Platelet Additive Solution |
| WO2008022651A1 (en) * | 2006-08-21 | 2008-02-28 | Antoine Turzi | Process and device for the preparation of platelet rich plasma for extemporaneous use and combination thereof with skin and bone cells |
| US8106008B2 (en) | 2006-11-03 | 2012-01-31 | Biomimetic Therapeutics, Inc. | Compositions and methods for arthrodetic procedures |
| US20080195476A1 (en) * | 2007-02-09 | 2008-08-14 | Marchese Michael A | Abandonment remarketing system |
| US8067151B2 (en) * | 2007-02-09 | 2011-11-29 | Canadian Blood Services | Cold storage of pegylated platelets at about or below 0° C. |
| US7964339B2 (en) * | 2007-02-09 | 2011-06-21 | Canadian Blood Services | Cold storage of modified platelets |
| WO2008127639A1 (en) | 2007-04-12 | 2008-10-23 | Biomet Biologics, Llc | Buoy suspension fractionation system |
| US8328024B2 (en) | 2007-04-12 | 2012-12-11 | Hanuman, Llc | Buoy suspension fractionation system |
| WO2009026073A1 (en) * | 2007-08-22 | 2009-02-26 | Caridianbct Biotechnologies, Llc | Prevention of transfusion related acute lung injury using riboflavin and light |
| US8835104B2 (en) * | 2007-12-20 | 2014-09-16 | Fenwal, Inc. | Medium and methods for the storage of platelets |
| EP2259807B1 (en) | 2008-02-07 | 2013-04-24 | Biomimetic Therapeutics, Inc. | Compositions for distraction osteogenesis |
| EP2620139B1 (en) | 2008-02-27 | 2016-07-20 | Biomet Biologics, LLC | Interleukin-1 receptor antagonist rich solutions |
| WO2009111338A1 (en) * | 2008-02-29 | 2009-09-11 | Biomet Manufacturing Corp. | A system and process for separating a material |
| JP4528863B2 (ja) * | 2008-02-29 | 2010-08-25 | ヘモネティクス・コーポレーション | アフェレーシス装置 |
| KR20110067035A (ko) | 2008-09-09 | 2011-06-20 | 바이오미메틱 세라퓨틱스, 인크. | 건 및 인대 손상의 치료를 위한 혈소판-유래 성장 인자 조성물 및 방법 |
| US20100081985A1 (en) * | 2008-10-01 | 2010-04-01 | Caridianbct, Inc. | Platelet Additive Solution For Leukoreducing White Blood Cells In Apheresed Platelets |
| US8187475B2 (en) | 2009-03-06 | 2012-05-29 | Biomet Biologics, Llc | Method and apparatus for producing autologous thrombin |
| US8313954B2 (en) | 2009-04-03 | 2012-11-20 | Biomet Biologics, Llc | All-in-one means of separating blood components |
| US9011800B2 (en) | 2009-07-16 | 2015-04-21 | Biomet Biologics, Llc | Method and apparatus for separating biological materials |
| CN102811622A (zh) | 2010-02-22 | 2012-12-05 | 生物模拟治疗公司 | 用于治疗腱病的血小板衍生生长因子组合物和方法 |
| JP2013524784A (ja) | 2010-04-08 | 2013-06-20 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 血小板の保存のためのゼオドレーション法 |
| US8591391B2 (en) | 2010-04-12 | 2013-11-26 | Biomet Biologics, Llc | Method and apparatus for separating a material |
| US11901069B2 (en) | 2010-08-12 | 2024-02-13 | Fenwal, Inc. | Processing blood donation data for presentation on operator interface |
| US11462321B2 (en) | 2010-08-12 | 2022-10-04 | Fenwal, Inc. | Mobile applications for blood centers |
| US8485828B2 (en) * | 2010-08-12 | 2013-07-16 | Fenwal, Inc. | Methods and systems for blood collection operator training |
| US9555171B2 (en) | 2010-09-30 | 2017-01-31 | Depuy Mitek, Llc | Methods and devices for collecting separate components of whole blood |
| US9402866B2 (en) | 2011-04-07 | 2016-08-02 | Fenwal, Inc. | Automated methods and systems for providing platelet concentrates with reduced residual plasma volumes and storage media for such platelet concentrates |
| US20140043930A1 (en) | 2011-05-03 | 2014-02-13 | Fenwal, Inc. | Platelet resuspension method and apparatus |
| EP2806914B1 (en) | 2012-01-23 | 2021-09-22 | Estar Technologies Ltd | A system and method for obtaining a cellular sample enriched with defined cells such as platelet rich plasma(prp) |
| WO2014011416A2 (en) | 2012-07-11 | 2014-01-16 | Biomimetic Therapeutics, Llc | Cell-based assay for neutralizing antibodies |
| US9642956B2 (en) | 2012-08-27 | 2017-05-09 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
| US10208095B2 (en) | 2013-03-15 | 2019-02-19 | Biomet Manufacturing, Llc | Methods for making cytokine compositions from tissues using non-centrifugal methods |
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| US9950035B2 (en) | 2013-03-15 | 2018-04-24 | Biomet Biologics, Llc | Methods and non-immunogenic compositions for treating inflammatory disorders |
| US9550028B2 (en) | 2014-05-06 | 2017-01-24 | Biomet Biologics, LLC. | Single step desiccating bead-in-syringe concentrating device |
| US12440835B2 (en) | 2019-01-21 | 2025-10-14 | Vias Partners, Llc | Methods, systems and apparatus for separating components of a biological sample |
| US12007382B2 (en) | 2019-10-31 | 2024-06-11 | Crown Laboratories, Inc. | Systems, methods and apparatus for separating components of a sample |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE32874E (en) * | 1982-11-01 | 1989-02-21 | Gail A. Rock | Plasma-free medium for platelet storage |
| US5462752A (en) * | 1994-07-28 | 1995-10-31 | Prp, Inc. | Inhibition of platelet binding |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US32874A (en) * | 1861-07-23 | Electro-magnet | ||
| US4828976A (en) * | 1983-12-29 | 1989-05-09 | Thomas Jefferson University | Glucose free media for storing blood platelets |
| US5234918A (en) * | 1988-04-04 | 1993-08-10 | American Cyanamid Company | Certain phosphinyl-oxy-phenyl-methyl-pyridinium-hydroxide inner salts useful as antagonists of PAF |
| US5622867A (en) * | 1994-10-19 | 1997-04-22 | Lifecell Corporation | Prolonged preservation of blood platelets |
| US6063624A (en) * | 1997-06-09 | 2000-05-16 | Baxter International Inc. | Platelet suspensions and methods for resuspending platelets |
-
1997
- 1997-06-09 US US08/871,115 patent/US6063624A/en not_active Expired - Lifetime
-
1998
- 1998-05-15 JP JP50247199A patent/JP2002503250A/ja not_active Ceased
- 1998-05-15 WO PCT/US1998/010029 patent/WO1998056247A1/en not_active Ceased
- 1998-05-15 EP EP98921239A patent/EP1001675A4/en not_active Withdrawn
- 1998-05-15 AU AU73896/98A patent/AU738348B2/en not_active Expired
- 1998-05-15 BR BR9810088-2A patent/BR9810088A/pt not_active IP Right Cessation
- 1998-05-15 CA CA002290389A patent/CA2290389A1/en not_active Abandoned
-
2000
- 2000-01-24 US US09/490,191 patent/US6326197B1/en not_active Expired - Lifetime
-
2001
- 2001-10-26 US US10/029,785 patent/US6613566B2/en not_active Expired - Lifetime
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE32874E (en) * | 1982-11-01 | 1989-02-21 | Gail A. Rock | Plasma-free medium for platelet storage |
| US5462752A (en) * | 1994-07-28 | 1995-10-31 | Prp, Inc. | Inhibition of platelet binding |
Non-Patent Citations (1)
| Title |
|---|
| GULLIKSSON, H ET AL ( 1993) TRANSFUSION 33(4) 301-303 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US6063624A (en) | 2000-05-16 |
| US6613566B2 (en) | 2003-09-02 |
| WO1998056247A1 (en) | 1998-12-17 |
| BR9810088A (pt) | 2000-08-08 |
| US6326197B1 (en) | 2001-12-04 |
| AU7389698A (en) | 1998-12-30 |
| CA2290389A1 (en) | 1998-12-17 |
| EP1001675A4 (en) | 2004-10-13 |
| US20020110914A1 (en) | 2002-08-15 |
| EP1001675A1 (en) | 2000-05-24 |
| JP2002503250A (ja) | 2002-01-29 |
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