AU7195694A - Benzimidazole derivatives useful as dopamine receptor antagonist, 5-ht receptor agonist or alpha1 receptor antagonist - Google Patents

Benzimidazole derivatives useful as dopamine receptor antagonist, 5-ht receptor agonist or alpha1 receptor antagonist

Info

Publication number
AU7195694A
AU7195694A AU71956/94A AU7195694A AU7195694A AU 7195694 A AU7195694 A AU 7195694A AU 71956/94 A AU71956/94 A AU 71956/94A AU 7195694 A AU7195694 A AU 7195694A AU 7195694 A AU7195694 A AU 7195694A
Authority
AU
Australia
Prior art keywords
receptor antagonist
receptor
alpha1
benzimidazole derivatives
derivatives useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU71956/94A
Inventor
Chie Nomura
Teruo Oku
Kozo Sawada
Hirokazu Tanaka
Takumi Yatabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939314908A external-priority patent/GB9314908D0/en
Priority claimed from GB939317508A external-priority patent/GB9317508D0/en
Priority claimed from GB9408003A external-priority patent/GB9408003D0/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of AU7195694A publication Critical patent/AU7195694A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
AU71956/94A 1993-07-19 1994-07-19 Benzimidazole derivatives useful as dopamine receptor antagonist, 5-ht receptor agonist or alpha1 receptor antagonist Abandoned AU7195694A (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB939314908A GB9314908D0 (en) 1993-07-19 1993-07-19 Novel compounds and their preparation
GB9314908 1993-07-19
GB939317508A GB9317508D0 (en) 1993-08-23 1993-08-23 Novel compounds and their preparation
GB9317508 1993-08-23
GB9408003A GB9408003D0 (en) 1994-04-22 1994-04-22 Novel compounds and their preparation
GB9408003 1994-04-22
PCT/JP1994/001182 WO1995003298A1 (en) 1993-07-19 1994-07-19 BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST

Publications (1)

Publication Number Publication Date
AU7195694A true AU7195694A (en) 1995-02-20

Family

ID=27266780

Family Applications (1)

Application Number Title Priority Date Filing Date
AU71956/94A Abandoned AU7195694A (en) 1993-07-19 1994-07-19 Benzimidazole derivatives useful as dopamine receptor antagonist, 5-ht receptor agonist or alpha1 receptor antagonist

Country Status (3)

Country Link
JP (1) JPH09505029A (en)
AU (1) AU7195694A (en)
WO (1) WO1995003298A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2723091B1 (en) * 1994-07-29 1996-11-08 Esteve Labor Dr TETRAHYDROPYRIDINE- (6,4-HYDROXYPIPERIDINE) ALKYLAZOLES
ES2117934B1 (en) * 1994-07-29 1999-04-01 Esteve Labor Dr TETRAHIDROPIRIDINAS (0 4-HIDROXIPIPERIDINAS) ALQUILAZOLES.
US5889010A (en) * 1995-05-18 1999-03-30 Pfizer Inc. Benzimidazole derivatives having dopaminergic activity
GB9518552D0 (en) * 1995-09-11 1995-11-08 Fujisawa Pharmaceutical Co New heterocyclic compounds
ES2109190B1 (en) * 1996-03-22 1998-07-01 Univ Madrid Complutense NEW BENCIMIDAZOLE DERIVATIVES AFFINATED BY 5-HT / 5-HT SEROTONINERGIC RECEPTORS
GB9613423D0 (en) * 1996-06-26 1996-08-28 Lilly Industries Ltd Pharmaceutical compounds
JP2004526781A (en) * 2001-04-20 2004-09-02 ワイス Heterocyclylalkoxy-, -alkylthio- and -alkylaminobenzazole derivatives as 5-hydroxytryptoamine-6 ligands
BRPI0417811A (en) * 2003-12-18 2007-03-27 Tibotec Pharm Ltd aminobenzimidazoles and benzimidazoles as respiratory syncytial virus replication inhibitors
AR054045A1 (en) * 2005-05-18 2007-05-30 Neuraxon Inc BENZOIMIDAZOL COMPOUNDS REPLACED WITH NON-INHIBITORY DUAL ACTIVITY AND MU AGIOIST OPIOID
WO2008001883A1 (en) * 2006-06-29 2008-01-03 Nissan Chemical Industries, Ltd. α-AMINO ACID DERIVATIVE AND PHARMACEUTICAL COMPRISING THE SAME AS ACTIVE INGREDIENT

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166853A (en) * 1978-05-05 1979-09-04 The Upjohn Company Antihypertensive 7-trifluoromethyl-4-aminoquinolones
GB8610432D0 (en) * 1986-04-29 1986-06-04 Akzo Nv Amino-thiazole & oxazole derivatives
FR2672052B1 (en) * 1991-01-28 1995-05-24 Esteve Labor Dr DERIVATIVES OF ARYL (OR HETEROARYL) -PIPERAZINYL-ALKYL-AZOLES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS.
FR2673628B1 (en) * 1991-03-07 1993-07-09 Esteve Labor Dr PROCESS FOR THE PREPARATION OF ARYL (OR HETEROARYL) -PIPERAZINYL-BUTYL-AZOLES DERIVATIVES.

Also Published As

Publication number Publication date
JPH09505029A (en) 1997-05-20
WO1995003298A1 (en) 1995-02-02

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