AU713472B2 - Phenylacetic acid derivatives, processes and intermediates for their preparation, and compositions comprising them - Google Patents

Phenylacetic acid derivatives, processes and intermediates for their preparation, and compositions comprising them Download PDF

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AU713472B2
AU713472B2 AU66147/96A AU6614796A AU713472B2 AU 713472 B2 AU713472 B2 AU 713472B2 AU 66147/96 A AU66147/96 A AU 66147/96A AU 6614796 A AU6614796 A AU 6614796A AU 713472 B2 AU713472 B2 AU 713472B2
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Eberhard Ammermann
Herbert Bayer
Norbert Gotz
Thomas Grote
Albrecht Harreus
Volker Harries
Gisela Lorenz
Bernd Muller
Ruth Muller
Hubert Sauter
Siegfried Strathmann
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BASF SE
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
    • A01N47/48—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —S—C≡N groups
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/50—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids the nitrogen atom being doubly bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
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    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/12—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, neither directly attached to a ring nor the nitrogen atom being a member of a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C251/36—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atoms of the oxyimino groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C251/40—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atoms of the oxyimino groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton
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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/50—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals
    • C07C251/60—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals of hydrocarbon radicals substituted by carboxyl groups
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/63—Carboxylic acid nitriles containing cyano groups and nitrogen atoms further bound to other hetero atoms, other than oxygen atoms of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C255/64—Carboxylic acid nitriles containing cyano groups and nitrogen atoms further bound to other hetero atoms, other than oxygen atoms of nitro or nitroso groups, bound to the same carbon skeleton with the nitrogen atoms further bound to oxygen atoms
    • C—CHEMISTRY; METALLURGY
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C329/00—Thiocarbonic acids; Halides, esters or anhydrides thereof
    • C07C329/02—Monothiocarbonic acids; Derivatives thereof
    • C07C329/04—Esters of monothiocarbonic acids
    • C07C329/06—Esters of monothiocarbonic acids having sulfur atoms of thiocarbonic groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C331/00—Derivatives of thiocyanic acid or of isothiocyanic acid
    • C07C331/02—Thiocyanates
    • C07C331/12—Thiocyanates having sulfur atoms of thiocyanate groups bound to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms, not being part of nitro or nitroso groups
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C333/00—Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C333/02—Monothiocarbamic acids; Derivatives thereof
    • C07C333/04—Monothiocarbamic acids; Derivatives thereof having nitrogen atoms of thiocarbamic groups bound to hydrogen atoms or to acyclic carbon atoms
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    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)

Abstract

Phenyl acetic acid derivatives of formula (I) in which: X is NOCH3, CHOCH3 and CHCH3; Y is NMR and O; R, R<1> are hydrogen and C1-4 alkyl; R<2> is hydrogen, C1-C6 alkyl, C1-C4 alkyl halide and C3-C6 cycloalkyl; R<3> is C4-C6 alkyl, substituted C1-C6 alkyl, possibly substituted C2-C6 alkinyl or possibly substituted C2-C6 alkenyl; R<4> is hydrogen, possibly substituted C1-C10 alkenyl, C2-C10 alkinyl, C1-10 alkyl carbonyl, C2-C10 alkenyl carbonyl, C3-C10 alkinyl carbonyl or C1-C10 alkyl sulphonyl, aryl, aryl carbonyl, aryl sulphonyl, hetaryl, hetaryl carbonyl or hetaryl sulphonyl; and their salts, a process and intermediate products for their production and their use.

Description

Phenylacetic acid derivatives, processes and intermediates for their preparation, and compositions comprising them The present invention relates to phenylacetic acid derivatives of the formula I RION-C(FP)C(R)NOCH2(I
O.C-Y-R'
the substituents and the index have the following meanings: :9 X is NOCH 3
CH-OCH
3 or CHCH 3 Y is NR or 0; R, Rlare hydrogen or Cl-C 4 -alkyl;
R
2 is hydrogen, Cl-C 6 -alkyl, Cl-C 4 -haloalkyl or
C
3
-C
6 -cycloalkyl;
R
3 is C 2
-C
6 -alkenyl;
:R
4 is hydrogen, Cl-C 1 -alkyl, C 3 -CS-cycloalkyl, C 2
-C
10 -alkenyl, C 2 -Cj 0 alkynyl, Cl-Cl-alkylcarbonyl, C 2 -Ci-alkenylcarbonyl,
C
3
-C
1 -alkynylcarbonyl or C-C 1 0 -alkylsulfonyl, it being possible for these radicals to be partially or fully halogenated or to have attached to them one to three of the following groups: cyano, nitro, hydroxyl, mercapto, amino, carboxyl, aminocarbonyl, aminothiocarbonyl, halogen,
C
1
-C
6 -alkyl, Cl-Cr,-haloalkyl, Cl-C 6 -alkylsulfonyl, Cl-C 6 -alkylsulfoxyl, Cl-C 6 -alkoxy, C 1
-C
6 -haloalkoxy, Cl-C 6 -alkoxycarbonyl, Cl-C 6 -alkylthio, Cl-C 6 -alkylamino, (the next page is page 2 which is intentionally blank) (THIS PAGE IS INTENTIONALLY BLANK) S
S.
S S
S.
SS*
S.
0050/ 46043 3 di-Cl-C 6 -alkylamino, Cl-C 6 -alkylaminocarbonyl, di-Cl-C 6 -alkylaminocarbonyl, Cl-C 6 -alkylaminothiocarbonyl, di-Cl-C 6 -alkylaminothiocarbonyl, C 2
-C
6 -alkenyl,
C
2
-C
6 -alkenyloxy, C 3
-C
6 -CYCloalkyl, C 3
-C
6 -CYCloalkyloxy, heterocyclyl, heterocyclyloxy, benzyl, benzyloxy, aryl, aryloxy, arylthio, hetaryl, hetaryloxy and hetarylthio, it being possible for the cyclic groups, in turn, to be partially or fully halogenated or to have attached to them one to three of the following groups: cyano, nitro, hydroxyl, mercapto, amino, carboxyl, aminocarbonyl, aminothiocarbonyl, halogen, Cl-C 6 -alkyl, Cl-C 6 -haloalkyl, Cl-C 6 -alkylsulfonyl, Cl-C 6 -alkylsulfoxyl, C 3
-C
6 -cycloalkyl, Cl-C 6 -alkoxy, Cl-C 6 -haloalkoxy, Cl-C 6 -alkyloxycarbonyl, Cl-C 6 -alkylthio, Cl-C 6 -alkylamino, di-Cl-C 6 -alkylamino, Cl-C 6 -alkylaminocarbonyl, di-Cl-C 6 -alkylaminocarbonyl, C 1
-C
6 -alkylaminothiocarbonyl, di-C 1
-C
6 -alkylaminothiocarbonyl, C 2
-C
6 -alkenyl, C2-C 6 -alkenyloxy, benzyl, benzyloxy, aryl, aryloxy, arylthio, hetaryl, hetaryloxy, hetarylthio or C(=NORa)-~An-Rb; aryl, arylcarbonyl, arylsulfonyl, hetaryl, hetarylcarbonyl or hetarylsulfonyl, it being possible for these radicals to be partially or fully halogenated or to have attached to them one to three of the following groups: cyano, nitro, hydroxyl, mercapto, amino, carboxyl, aminocarbonyl, aminothiocarbonyl, halogen, Cl-C 6 -alkyl, Cl-C 6 -haloalkyl, Cl-C 6 -alkylcarbonyl, Cl-C 6 -alkylsulfonyl, Cl-C 6 -alkylsulfoxyl, C 3
-C
6 -cycloalkyl, Cl-C 6 -alkoxy, Cl-C 6 -haloalkoxy, Cl-C 6 -alkyloxycarbonyl, Cl-C 6 -alkylthio, Cl-C 6 -alkylamino, di-Cl-C 6 -alkylamino, Cl-C 6 -alkylaminocarbonyl, di-Cl-C 6 alkylaminocarbonyl, Cl-C 6 -alkylaminothiocarbonyl, di-Cl-C 6 alkylaminothiocarbonyl, C 2
-C
6 -alkenyl, C 2
-C
6 -alkenyloxy, benzyl, benzyloxy, aryl, aryloxy, hetaryl, hetaryloxy or C(=NoRa)-An-.Rb; where A is oxygen, sulfur or nitrogen and the nitrogen having attached to it hydrogen or Cl-C 6 -alkyl; n is 0 or 1; Ra is hydrogen or Cl-C 6 -alkyl and Rb 45 Rb is hydrogen or Cl-C 6 -alkyl, and the salts thereof* The invention furthermore relates to processes and intermediates for the preparation of these compounds and to compositions comprising them for controlling animal pests and harmful fungi.
Phenylacetic acid derivatives for controlling pests have been disclosed in the literature [EP-A 422 597, EP-A 463 488, EP-A 370 629, EP-A 460 575, EP-A 472 300, WO-A 90/07,493, WO-A 92/13,830, WO-A 92/18,487; WO-A 95/18,789; WO-A 95/21,153; WO-A 95/21,154].
It was an object of the present invention to provide novel compounds with an improved action.
Accordingly, we have found that this object is achieved by the phenylacetic acid derivatives I defined at the outset. Moreover, see 20 we have found processes and intermediates for their preparation, compositions comprising them for controlling animal pests and harmful fungi, and their use for these purposes.
The compounds I are accessible by various routes by processes 25 known per se from the literature.
When synthesizing the compounds I, it is in principle irrelevant whether the group -C(X)-COYR 1 is first constructed or the group 2
)-C(R
3
)=NOR
4 The construction of the group -C(X)-COYR 1 for example, is known from the literature cited at the outset and from the following references: EP-A 242 070, EP-A 254 426, EP-A 370 629, EP-A 513 580, EP-A 656 352, PCT/EP 95/02013, EP-A 398 692.
1. When constructing the group -CH 2 0N=C(R 2
)-C(R
3
)=NOR
4 a procedure is generally followed in which a benzyl derivative of the formula II is reacted with a hydroxyimine of the formula III.
R4-ON=C(R 3 )-C(R2)=NOH L'-CH 2
C=X
A (I1) (11) O=C-Y-R 0050/46043
R
4
-ON=C(R
3
)-C(R
2
)=NOCH
2
C=X
I
O=C-Y-R
1
L
1 in formula II is a nucleophilically exchangeable leaving group, eg. halogen or sulfonate groups, preferably chlorine, bromine, iodine, mesylate, tosylate or triflate.
The reaction is carried out in a manner known per se in an inert organic solvent in the presence of a base, eg. sodium hydride, potassium hydroxide, potassium carbonate and triethylamine, by the methods described in Houben-Weyl, Vol. E 14b, p. 370 et seq. and Houben-Weyl, Vol. 10/1, p. 1189 et seq.
The hydroxyimine III required is obtained, for example, by reacting a corresponding dihydroxyimine IV with a nucleophilically substituted reagent VI R4-L 2
HON=C(R
3
)-C(R
2
)=NOH
(VI) (IV)
R
4
-ON=C(R
3
)-C(R
2
)=NOH
(IIl)
L
2 in formula VI is a nucleophilically exchangeable leaving group, eg. halogen or sulfonate groups, preferably chlorine, bromine, iodine, mesylate, tosylate or triflate.
The reaction is carried out in a manner known per se in an inert organic solvent in the presence of a base, eg. potassium carbonate, potassium hydroxide, sodium hydride, pyridine and triethylamine, by the methods described in Houben-Weyl, Vol. E 14b, p. 307 et seq., p. 370 et seq. and p. 385 et seq.; Houben-Weyl, Vol. 10/4, p. 55 et seq., p. 180 et seq.
and p. 217 et seq.; Houben-Weyl, Vol. E 5, p. 780 et seq.
1.1 Alternatively, the compounds I can also be obtained by first reacting the benzyl derivative II with the dihydroxyimino derivative IV to give a corresponding benzyl oxime of the formula V, V subsequently being reacted with the nucleophilically substituted reagent VI to give I.
0050/46043
HON=C(R
3
)-C(R
2
)=NOH
L
1
-CH
2 ,9
C=X
I
O=C-Y-R
1
HON=C(R
3
)-C(R
2
)=NO-CH
2
C=X
O=C-Y-R
1
R
4
-ON=C(R
3
)-C(R
2
)=NOCH
2
C=X
Y
O=C-Y-R
1
R
4
-L
2
(VI)
The reaction is carried out in a manner known per se in an inert organic solvent in the presence of a base, eg. potassium carbonate, potassium hydroxide, sodium hydride, pyridine and triethylamine, by the methods described in Houben-Weyl, Vol. 10/1, p. 1189 et seq.; Houben-Weyl, Vol. E 14b, p. 307 et seq., p. 307 et seq. and p. 385 et seq.; Houben-Weyl, Vol. 10/4, p. 55 et seq., p. 180 et seq. and p. 217 et seq.; Houben-Weyl, Vol. E 5, p. 780 et seq.
1.2 Analogously, hydroxyimine imine VII by IXb thereof.
it is also possible to prepare the required of the formula III from a carbonylhydroxyreacting it with a hydroxylamine IXa or a salt
R
4
-ONH
2 (IXa) or )NH3T dD (IXb)
O=C(R
3
)-C(R
2
)=NOH
(V1I) ON~ R 4
-ON=C(R
3
)-C(R
2
)=NOH
(111)
R
4
-C
QQ in formula IXb is the anion of an acid, in particular of an inorganic acid, eg. halide, such as chloride.
0050/46043 7 The reaction is carried out in a manner known per se in an inert organic solvent by the methods described in EP-A 513 580; Houben-Weyl, Vol. 10/4, p. 73 et seq.; Houben- Weyl, Vol. E 14b, p. 369 et seq. and p. 385 et seq.
The carbonylhydroxyimines VII which are not already known from the literature (eg. Chem. Ber. 46 (1913) 1864; J. Chem.
Soc. Perkin Trans. 2 (1994) 1, 415-420; Gazz. Chim. Ital. 63 (1933) 917 et seq.; J. Indian. Chem. Soc. 35 (1958) 898) can be prepared by similar methods.
1.3 Alternatively, the compounds I can also be obtained by first reacting the benzyl derivative II with the carbonylhydroxyimino derivative VII to give a corresponding benzyloxyimine of the formula VIII, VIII subsequently being reacted with the hydroxylamine IXa or a salt IXb thereof to give I.
O=C(R
3
)-C(R
2 )=NOH L 1
-CH
2 (VII) (II) c=X
O=C-Y-R
1
O=C(R
3
)-C(R
2
)=NO-CH
2 (VIII) c=X
O=C-Y-R'
IXa/IXb
R
4
-ON=C(R
3
)-C(R
2
)=NOCH
2
C=X
O=C-Y-R
1 The reaction is carried out in a manner known per se in an inert organic solvent by the methods described in Houben- Weyl, Vol. E 14b, p. 369 et seq.; Houben-Weyl, Vol. 10/1, p. 1189 et seq. and Houben-Weyl, Vol. 10/4, p. 73 et seq. or EP-A 513 580.
1.4 A further possibility of preparing the compounds I is to react the benzyl derivative II with N-hydroxyphthalimide followed by hydrazinolysis to give the benzylhydroxylamine IIa and to further react IIa with a carbonyl compound X.
0050/46043 0 SN-OH 0
N-OCH
2 '9
C=X
0
O=C-Y-R
1
R
4
-ON=C(R
3
)-C(R
2 )=0
(X
C=X
(II)
O=C-Y-R
H
2
NNH
2 >1
H
2
NO-CH
2
C=X
(lla)
I
O=C-Y-R
1 (la) The reaction is carried out in a manner known per se in an inert organic solvent by the methods described in EP-A 463 488, DE Application No. 42 28 867.3.
The carbonyl compound X which is required is obtained, for example, by reacting a corresponding hydroxyiminocarbonyl compound VIIa with a nucleophilically substituted reagent VI
R
4
-L
2
HON=C(R
3
)-C(R
2
)=O
(Vlla)
R
4
-ON=C(R
3
)-C(R
2
)=O
(X)
or by reacting a corresponding dicarbonyl compound XI with a hydroxylamine IXa or a salt IXb thereof
R
4
-ONH
2 (IXa) or NH3 (IXb)
O=C(R
3
)-C(R
2 0
(XI)
OM R 4
-ON=C(R
3
)-C(R
2 )=0
(X)
R
4
-O
The reactions are carried out in a manner known per se in an inert organic solvent by the methods described in EP-A 513 580, Houben-Weyl, Vol. 10/4, p. 55 et seq., p. 73 et seq., p. 180 et seq. and p. 217 et seq.; Houben-Weyl, Vol. E 14b, p. 307 et seq. and 369 et seq., Houben-Weyl, Vol. E 5, p. 780 et seq.
0050/46043 9 Accordingly, the compounds I can also be obtained by first reacting the benzylhydroxylamine IIa with the hydroxyimino derivative VIIa to give the corresponding benzyloxyimino derivative of the formula V, V subsequently being reacted as described above with the nucleophilically substituted reagent VI to give I.
HON=C(R
3
)-C(R
2
H
2
NO-CH
2
C=X
(VIIa) (Ha)
O=C-YR
1
HON=C(R)-C(R
2 )=NO-CH2
C=X
O=C-YR
1 R4-L 2
S---R
4 0N=C(R 3
)-C(R)=NO-CH
2
C=X
(I)
O=C-YR
1 1.6 Analogously, the compounds I can also be prepared by first converting the benzylhydroxylamine IIa with the dicarbonyl derivative of the formula XI to give the benzyloxyimino derivative of the formula VIII and subsequently reacting VIII with the hydroxylamine IXa or a salt IXb thereof as described above to give I.
O=C(R
3
)-C(R
2
H
2
NO-CH
2 (XI) (Ila)
C=X
O=C-YR
1
O=C(R
3
)-C(R
2
)=NO-CH
2
C=X
(VIII)
O=C-YR
1 IXa/IXb
R
4 0N=C(R 3
)-C(R
2
)=NO-CH
2
C=X
0=C-YR 1 0050/46043 1.7 Compounds VIII where R 3 is substituted or unsubstituted alkenyl can also be obtained starting from compounds VIIIa.
The C=C double bond of the alkenyl radical is constructed in a manner known per se in the sense of an aldol reaction by reacting VIIIa with a carbonyl compound VIIIb (eg.
Organikum [Laboratory Practical Inorganic Chemistry], Edition, p. 563 et seq.), the substituents R 3
R
3 and
R
3 being determined via the radical R 3 C(R) NOCH ,J
C=X
(Villa)
O=C-YR'
C(R
3
"R
3 (Vlllb) IXa/IXb
OW-
C=X
(VIII) O=C-YR 1 Compound VIII can be reacted described above.
to give compounds I as 1.8 Compounds I where R 3 is substituted or unsubstituted alkenyl can furthermore be synthesized starting from the halogen compounds VIIIc and following the equation below.
For reasons of clarity, the group C(=X)-COYR 1 in this equation is abbreviated to 0050/46043 11 0 r^i R 4 0 N r Hal NO Hal O 0 I~Ha (VIIIc) SP(C6H 5 3 P(C6H5)3 HaP O HaP
(C
6
H
53 P® (C 6
H
5 )3P 3, R2 1 R2 1 base base 0 f R 4 0 N
(C
6
H
5 3 N- (C6H5)3P 0 R3 2 N O3 R2 O=CR3"R3'"
O=CR
3
"R
3 0 R 3
R
3
NOR
4 No R3, O
R
3
NO
3' R 2 3' R2
(I)
The C=C double bond of the alkenyl radical is constructed in a manner known per se by means of a Wittig reaction (as shown in the diagram; cf. Houben-Weyl, Vol. Vlb, 4th Edition, p. 383 et seq.) or in a similar manner by means of a Wittig-Horner reaction. The group CR 3
'=CR
3
"R
3 r" corresponds to the alkenyl radical R 3 2. Compounds I where Y is oxygen are preferably obtained by first converting a compound X with a lactone XII by the methods described in EP-A 493 711 to give the corresponding benzoic acid XIII and converting XIII via the corresponding halides into the cyanocarboxylic acids XIV, which are converted into the a-keto ester XV via a Pinner reaction (Angew. Chem. 94, 1 (1982)) and subsequently into the derivatives I (cf. EP-A 348 766, DE-A 37 05 389, EP-A 178 826, DE-A 36 23 921).
0050/46043 12
R
5
-ON=C(R
4
)-C(R
3 )=NOH +0 0 (X (XII) 3p ~R 4
-ON=C(R
3
)-C(R
2 )=NO-0H 2 _9 (XIII) C0 2
H
OPR
4
_ON=C(R
3
)-C(R
2
)=NO-CH
2 __9(HaIkhalogen) (XIII.a) COHal ~R4_0N=C(R 3
)-C(R
2
)=NO-CH
2
(XIV)I
4
-ON-C(R
3
)-C(R
2
)=NO-CH
2 (X)c=O (XV) I lpR4ON=C(R3)C(R2)=NCH 2
C=X
C0 2
R
1 Compounds I where R 1 is hydrogen are obtained by this process by hydrolyzing the esters XV and subsequently reacting the product to give I.
3. Compounds I where Y is NR are preferably obtained by first converting a compound X with a lactone XII by the methods described in EP-A 493 711 to give the corresponding benzoic acid XIII and converting XIII via the corresponding halides into the cyanocarboxylic acids XIV, which are then converted into the cz-keto esters XV via a Pinner reaction (Angew. Chem.
94, 1 (1982)). Amidation of the derivatives XV gives the corresponding carboxamides XVI, which are subsequently converted into the compounds I.
0050 /46 043 0:1
R
5
-ON=C(R
4
)-C(R
3
)=NOH
R
4
-ON=C(R
3
)-C(R
2
)=NO-CH
2 9 (XIII) C0 2
H
R
4
-ON=C(R
3
)-C(R
2 )=NO-0H 2 (XIII.a) COHal
R
4 -0N=C(R 3
)-C(R
2
)=NO-CH
2 (XIV)1
UN
R
4
-ON=C(R
3
)-C(R
2 )=NO-0H 2 (XV)
C=
R
4 -0N=C(R 3
)-C(R
2
)=NO-CH
2 0=0 (XVI)
I
0=C-NR R4ON=C(R3)-C(R2)=NOCH 2
C=X
I=NR
(HaI=haiogen)
(R#H)
4. In a modification of the process described also possible to obtain the compounds XVI hydrogen directly from the carboxylic acid reacting them with isocyanates followed by (EP-A 547 825).
under it is where R is halides by hydrolysis 0050/46043 14
R
4
-ON-C(R
3
)-C(R
2
)=NO-CH
2 -9R1-NC COHaI (Hal=halogen) (XIII.a)
R
4
-ON-C(R
3
)-C(R
2
)=NO-CH
2 u=C.-NRR 1
(XVI)
5. In a further variant, compounds XVI are obtained by metallating an ortho-halogen compound with oxalyl chloride and then converting the product into the corresponding keto acid chloride, which is subsequently converted with an amine to give the corresponding amide XVI (cf. J. Org. Chem. 46, 212 et seq. (1981); DE-A 40 42 280; Houben Weyl, Vol. p. 972 et seq.).
R
4
-ON-C(R
3
)-C(R
2
)=NO-CH
2 Hal (HaI=halogen)
R
4
-ON-C(R
3
)-C(R
2
)=NO-CH
2
R
4
-ON=C(R
3
)-C(R
2
)=NO-CH
2 C=0
(XVI)I
O=C-NRR
1 6. In a further variant, the compounds I where Y is NR are obtained starting from the keto esters XV by first derivatizing the keto function and converting the resulting derivatives with a suitable amine into the amide (Houben- Weyl, Vol. E5, p. 941 et seq.) ~NT 0/ 0050/46043
R
4
-ON=C(R
3
)-C(R
2
)=NO-CH
2 C=0
(XV)
(RoH) C0 2
R
S R 4
-ON=C(R
3
)-C(R
2
)=NO-CH
2
C=X
CO
2
R
R4-ON=C(R 3
)-C(R
2
)=NO-CH
2
C=X
(1)
O=C-NRR
1 Those compounds II which are not already known (EP-A 513 580, EP-A 477 631, EP-A 463 488, EP-A 585 751, EP-A 400 417, EP-A 251 082) can be prepared by the methods described therein.
Due to their C=C and C=N double bonds, the preparation of the compounds I may result in E/Z isomer mixtures, which can be separated into the individual compounds in the customary manner, for example by crystallization or chromatography.
If the synthesis results in isomer mixtures, however, it is generally not absolutely necessary to separate these mixtures since the individual isomers can be converted into each other in some cases during formulation for use or upon use (eg. under the action of light, acids or bases). Similar conversions can also take place after application, for example in the treated plant in the case of the treatment of plants, or in the harmful fungus or animal pest to be controlled.
With a view to the C=X double bond, the E isomers of the compounds I are preferred with a view to their activity (configuration based on the -OCH 3 or the -CH 3 group relative to the (O=C)YR 1 group).
With a view to the -C(R 2
)=NOCH
2 double bond, the cisisomers of the compounds I are generally preferred regarding their activity (configuration based on the radical R 2 relative to the -OCH 2 Sgroup).
0050/46043 16 In the definitions of the compounds I given at the outset, collective terms were used which generally represent the following groups: Halogen: fluorine, chlorine, bromine and iodine; Alkyl: straight-chain or branched alkyl groups having 1 to 4, 6 or 10 carbon atoms, eg. C 1
-C
6 -alkyl, such as methyl, ethyl, propyl, 1-methylethyl, butyl, 1-methylpropyl, 2-methylpropyl, 1,1-dimethylethyl, pentyl, 1-methylbutyl, 2-methylbutyl, 3-methylbutyl, 2,2-dimethylpropyl, 1-ethylpropyl, hexyl, 1,1-dimethylpropyl, 1,2-dimethylpropyl, 1-methylpentyl, 2-methylpentyl, 3-methylpentyl, 4-methylpentyl, 1,1-dimethylbutyl, 1,2-dimethylbutyl, 1,3-dimethylbutyl, 2,2-dimethylbutyl, 2,3-dimethylbutyl, 3,3-dimethylbutyl, 1-ethylbutyl, 2-ethylbutyl, 1,1,2-trimethylpropyl, 1,2,2-trimethylpropyl, 1-ethyl-1-methylpropyl and 1ethyl-2-methylpropyl; Alkylamino: an amino group which has attached to it a straightchain or branched alkyl group having 1 to 6 carbon atoms as mentioned above; Dialkylamino: an amino group which has attached to it two straight-chain or branched alkyl groups which are independent of one another and have in each case 1 to 6 carbon atoms as mentioned above; Alkylcarbonyl: straight-chain or branched alkyl groups having 1 to 10 carbon atoms which are bonded to the skeleton via a carbonyl group Alkylsulfonyl: straight-chain or branched alkyl groups having 1 to 6 or 10 carbon atoms which are bonded to the skeleton via a sulfonyl group (-SO 2 Alkylsulfoxyl: straight-chain or branched alkyl groups having 1 to 6 carbon atoms which are bonded to the skeleton via a sulfoxyl group Alkylaminocarbonyl: alkylamino groups having 1 to 6 carbon atoms as mentioned above which are bonded to the skeleton via a carbonyl group Dialkylaminocarbonyl; dialkylamino groups having in each case 1 to 6 carbon atoms per alkyl radical as mentioned above which are bonded to the skeleton via a carbonyl group 0050/46043 17 Alklaminothiocarbonyl: alkylamino groups having 1 to 6 carbon atoms as mentioned above which are bonded to the skeleton via a thiocarbonyl group Dialkylaminothiocarbonyl: dialkylamino groups having in each case 1 to 6 carbon atoms per alkyl radical as mentioned above which are bonded to the skeleton via a thiocarbonyl group Haloalkyl: straight-chain or branched alkyl groups having 1 to 6 carbon atoms, it being possible for some or all of the hydrogen atoms in these groups to be replaced by halogen atoms as mentioned above, eg. C 1
-C
2 -haloalkyl, such as chloromethyl, dichloromethyl, trichloromethyl, fluoromethyl, difluoromethyl, trifluoromethyl, chlorofluoromethyl, dichlorofluoromethyl, chlorodifluoromethyl, 1-fluoroethyl, 2-fluoroethyl, 2,2-difluoroethyl, 2,2,2-trifluoroethyl, 2-chloro-2-fluoroethyl, 2-chloro-2,2-difluoroethyl, 2,2-dichloro-2-fluoroethyl, 2,2,2-trichloroethyl and pentafluoroethyl; Alkoxy: straight-chain or branched alkyl groups having 1 to 4 or 6 carbon atoms as mentioned above which are bonded to the skeleton via an oxygen atom eg. C 1
-C
6 -alkoxy, such as methyloxy, ethyloxy, propyloxy, 1-methylethyloxy, butyloxy, 1-methylpropyloxy, 2-methylpropyloxy, 1,1-dimethylethyloxy, pentyloxy, 1-methylbutyloxy, 2-methylbutyloxy, 3-methylbutyloxy, 2,2-dimethylpropyloxy, 1-ethylpropyloxy, hexyloxy, 1,1-dimethylpropyloxy, 1,2-dimethylpropyloxy, 1-methylpentyloxy, 2-methylpentyloxy, 3-methylpentyloxy, 4-methylpentyloxy, 1,1-dimethylbutyloxy, 1,2-dimethylbutyloxy, 1,3-dimethylbutyloxy, 2,2-dimethylbutyloxy, 2,3-dimethylbutyloxy, 3,3-dimethylbutyloxy, 1-ethylbutyloxy, 2-ethylbutyloxy, 1,1,2-trimethylpropyloxy, 1,2,2-trimethylpropyloxy, 1-ethyl-1-methylpropyloxy and 1-ethyl-2-methylpropyloxy; Alkoxycarbonyl: straight-chain or branched alkyl groups having 1 to 6 carbon atoms which are bonded to the skeleton via an oxycarbonyl group Haloalkoxy: straight-chain or branched alkyl groups having 1 to 6 carbon atoms, it being possible for some or all of the hydrogen atoms in these groups to be replaced by halogen atoms as mentioned above, and these groups being bonded to the skeleton via an oxygen atom; Alkylthio: straight-chain or branched alkyl groups having 1 to 4 or 6 carbon atoms as mentioned above which are bonded to the Sskeleton via a sulfur atom eg. C 1
-C
6 -alkylthio such as 0050/46043 18 methyithic, ethylthio, propylthio, 1-methylethylthio, butylthio, 1-methylpropylthio, 2-methyipropyithic, 1, 1-dimethylethylthio, pentylthio, 1-methylbutylthio, 2-methylbutylthio, 3-methylbutylthio, 2, 2-di-methylpropylthio, 1-ethyipropyithio, hexylthio, 1, 1-dimethylpropylthio, 1, 2-dimethyipropyithic, 1-methylpentylthio, 2-methylpentylthio, 3-methylpentylthio, 4-methylpentylthio, 1, 1-dimethylbutylthio, 1, 2-dimethylbutylthio, 1, 3-dimethylbutylthio, 2, 2-dimethylbutylthio, 2, 3-dimethylbutylthio, 3, 3-dimethylbutylthio, 1-ethylbutyithic, 2-ethylbutylthio, 1, 1, 2-trimethylpropylthio, 1,2, 2-trimethylpropylthio, 1-ethyl-1-methylpropylthio and 1-ethyl-2-methylpropylthio; Alkenvi: straight-chain or branched alkenyl groups having 2 to 6 or 10 carbon atoms and one double bond in any desired position, eg. C 2
-C
6 -alkenyl, such as ethenyl, 1-propenyl, 2-propenyl, 1-methylethenyl, 1-butenyl, 2-butenyl, 3-butenyl, 1-methyl-ipropenyl, 2-methyl-1-propenyl, 1-methyl-2-propenyl, 2-methyl-2propenyl, 1-pentenyl, 2-pentenyl, 3-pentenyl, 4-pentenyl, 1-methyl- 1-butenyl, 2-methyl- 1-butenyl, 3-methyl- 1-butenyl, 1-methyl-2-butenyl, 2-methyl-2-butenyl, 3-methyl-2-butenyl, 1-methyl-3-butenyl, 2-methyl-3-butenyl, 3-methyl-3-butenyl, 1, 1-dimethyl-2-propenyl, 1, 2-dimethyl-1-propenyl, 1, 2-dimethyl- 2-propenyl, 1-ethyl-1-propenyl, 1-ethyl-2-propenyl, 1-hexenyl, 2-hexenyl, 3-hexenyl, 4-hexenyl, 5-hexenyl, 1-methyl-1-pentenyl, 2-methyl-1-pentenyl, 3-methyl-1-pentenyl, 4-methyl-1-pentenyl, 1-methyl-2-pentenyl, 2-methyl-2-pentenyl, 3-methyl-2-pentenyl, 4-methyl-2-pentenyl, 1-methyl-3-pentenyl, 2-methyl-3-pentenyl, 3-methyl-3-pentenyl, 4-methyl-3-pentenyl, 1-methyl-4-pentenyl, 2-methyl-4-pentenyl, 3-methyl-4-pentenyl, 4-methyl-4-pentenyl, 1, 1-dimethyl-2-butenyl, 1, 1-dimethyl-3-butenyl, 1, 2-dimethyl-1butenyl, 1, 2-dimethyl-2-butenyl, 1, 2-dimethyl-3-butenyl, 1, 3-dimethyl-1-butenyl, 1, 3-dimethyl-2-butenyl, 1, 3-dimethyl-3-butelyl, 2, 2-dimethyl-3-butenyl, 2, 3-dimethyl-1-butenyl, 2, 3-dimethyl-2butenyl, 2, 3-dimethyl-3-butenyl, 3, 3-dimethyl-1-butenyl, 3, 3-dimethyl-2-butenyl, 1-ethyl-1-butenyl, 1-ethyl-2-butenyl, 1-ethyl- 3-butenyl, 2-ethyl-1-butenyl, 2-ethyl-2-butenyl, 2-ethyl-3butenyl, 1,1, 2-trimethyl-2-propenyl, 1- ethyl-1-methyl-2propenyl, 1-ethyl-2-methyl-1-propenyl and 1-ethyl-2-methyl-2propenyl; Alkenyloxy: straight-chain or branched alkenyl groups having 2 to 6 carbon atoms and one double bond in any desired position which are bonded to the skeleton via an oxygen atom 0050/46043 19 Alkenylthio: straight-chain or branched alkenyl groups having 2 to 6 carbon atoms and one double bond in any position which are bonded to the skeleton via a sulfur atom Alkenylamino: an amino group which has attached to it a straightchain or branched alkenyl group having 2 to 6 carbon atoms as mentioned above; Alkenylcarbonyl: straight-chain or branched alkenyl groups having 2 to 10 carbon atoms and one double bond in any desired position which are bonded to the skeleton via a carbonyl group Alkynyl: straight-chain or branched alkynyl groups having 2 to carbon atoms and one triple bond in any desired position, eg.
C
2
-C
6 -alkynyl, such as ethynyl, 2-propynyl, 2-butynyl, 3-butynyl, l-methyl-2-propynyl, 2-pentynyl, 3-pentynyl, 4-pentynyl, 1methyl-2-butynyl, 1-methyl-3-butynyl, 2-methyl-3-butynyl, 1,1-dimethyl-2-propynyl, 1-ethyl-2-propynyl, 2-hexynyl, 3-hexynyl, 4-hexynyl, 5-hexynyl, l-methyl-2-pentynyl, l-methyl-3-pentynyl, 1-methyl-4-pentynyl, 2-methyl-3-pentynyl, 2-methyl-4-pentynyl, 3-methyl-4-pentynyl, 4-methyl-2-pentynyl, 1,1-dimethyl-2-butynyl, 1,1-dimethyl-3-butynyl, 1,2-dimethyl-3-butynyl, 2,2-dimethyl-3-butynyl, 1-ethyl-2-butynyl, 1-ethyl-3-butynyl, 2-ethyl-3-butynyl and 1-ethyl-l-methyl-2-propynyl; Alkynyloxy: straight-chain or branched alkynyl groups having 2 to 6 carbon atoms and one triple bond in any position which are bonded to the skeleton via an oxygen atom Alkynylthio: straight-chain or branched alkynyl groups having 2 to 6 carbon atoms and one triple bond in any position which are bonded to the skeleton via a sulfur atom Alkynylamino: an amino group which has attached to it a straightchain or branched alkynyl group having 2 to 6 carbon atoms as mentioned above; Alkynylcarbonyl: straight-chain or branched alkynyl groups having 3 to 10 carbon atoms and one triple bond in any desired position which are bonded to the skeleton via a carbonyl group Cycloalkyl: monocyclic alkyl groups having 3 to 6 carbon ring members, eg. cyclopropyl, cyclobutyl, cyclopentyl and cyclohexyl; 0050/46043 Cycloalkoxy: monocyclic alkyl groups having 3 to 6 carbon ring members as mentioned above which are bonded to the skeleton via an oxygen atom Cycloalkvlthio: monocyclic alkyl groups having 3 to 6 carbon ring members as mentioned above which are bonded to the skeleton via a sulfur atom Cycloalkvlamino: an amino group which has attached to it a monocyclic alcohol group having 3 to 6 carbon ring members as mentioned above; Cycloalkenyl: monocyclic alkenyl groups having 5 to 8 carbon ring members, eg. cyclopentenyl, cyclohexenyl, cycloheptenyl and cyclooctenyl; Cycloalkenyloxy: monocyclic alkenyl groups having 5 to 8 carbon ring members as mentioned above which are bonded to the skeleton via an oxygen atom Cycloalkenvythio: monocyclic alkenyl groups having 5 to 8 carbon ring members as mentioned above which are bonded to the skeleton via a sulfur atom Cycloalkenylamino: an amino grou which has attached to it a monocyclic alkenyl group having 5 to 8 carbon ring members; Heterocvclvl, heterocyclyloxy. heterocycly1vlthio or heterocyclylamino: three- to six-membered, saturated or partially unsaturated mono- or polycyclic heterocycles which contain one to three hetero atoms selected from a group consisting of oxygen, nitrogen and sulfur and which are bonded to the skeleton directly or (heterocyclyloxy) via an oxygen atom, or (heterocyclylthio) via a sulfur atom or (heterocyclylamino) via a nitrogen atom eg.
2-tetrahydrofuranyl, oxiranyl, 3-tetrahydrofuranyl, 2-tetrahydrothienyl, 3-tetrahydrothienyl, 2-pyrrolidinyl, 3-pyrrolidinyl, 3-isoxazoldinyl [sic], 4-isoxazolidinyl, 3-isothiazolidinyl, 4-isothiazolidinyl, 3-pyrazolidinyl, 4-pyrazolidinyl, 5-pyrazolidinyl, 2-oxazolidinyl, 4-oxazolidinyl, 5-oxazolidinyl, 2-thiazolidinyl, 4-thiazolidinyl, 5-thiazolidinyl, 2-imidazolidinyl, 4-imidazolidinyl, 1,2,4-oxadiazolidin-3-yl, 1,2,4-oxadiazolidin-5-yl, 1,2,4-thiadiazolidin-3-yl, 1,2,4-thiadiazolidin-5-yl, 1,2,4-triazolidin- 3-yl, 1,3,4-oxadiazolidin-2-yl, 1,3,4-thiadiazolidin-2-yl, 1,3,4-triazolidin-2-yl, 2,3-dihydrofur-2-yl, 2,3-dihydrofur-3-yl, 2,3-dihydrofur-4-yl, 2,3-dihydrofur-5-yl, 2,5-dihydrofur-2-yl, 2,5-dihydrofur-3-yl, 2,3-dihydrothien-2-yl, 2,3-dihydrothien- 0050/46043 21 3-yl, 2, 3-dihydrothien-4-yl, 2, 3-dihydrothien-5-yl, 2, thien-2-yl, 2, 5-dihydrothien-3-yl, 2,3-dihydropyrrol-2-yl, 2 ,3-dihydropyrrol-3-yl, 2,3-dihydropyrrol-4-yl, 2, 3-dihydro- 2, 5-dihydropyrrol-2-yl, 2, 5-dihydropyrrol-3-yl, 2, 3-dihydroisoxazol-3-yl, 2, 3-dihydroisoxazol-4-yl, 2, 3-dihydro- 4, 5-dihydroisoxazol-3-yl, 4, 4-yl, 4, 5-dihydroisoxazol-5-yl, 2, 5-dihydroisothiazol-3-yl, 2, 5-dihydroisothiazo.-4-yl, 2, 2, 3-dihydroisopyrazol-3-yl, 2, 3-dihydroisopyrazol-4-yl, 2, 3-dihydroisopyrazol-5-yl, 4 ,5-dihydroisopyrazol-3-yl, 4, 5-dihydroisopyrazol-4-yl, 4, 2, 5-dihydroisopyrazol-3-yl, 2, 5-dihydroisopyrazol-4-yl, 2, 5-dihydroisopyrazol-5-yl, 2, 3-dihydrooxazol-3-yl, 2, 3-dihydrooxazol-4-yl, 2 ,3-dihydrooxazol-5-yl, 4, oxazol-3-yl, 4,5-dihydrooxazol-4-yl, 4,5-dihydrooxazol-5-yl, 2, 5-dihydrooxazol-3-yl, 2,5-dihydrooxazol-4-yl, 2, 2,3-dihydrothiazol-2-yl, 2,3-dihydrothiazol-4-yl, 2, 3-dihydrothiazol-5-yl, 4, 5-dihydrothiazol-2-yl, 4, thiazol-4-yl, 4, 5-dihydrothiazol-5-yl, 2,5-dihydrothiazol-2-yl, 2, 5-dihydrothiazol-4-yl, 2, 5-dihydrothiazol-5-yl, 2, 3-dihydroimidazol-2-yl, 2, 3-dihydroimidazol-4-yl, 2,3-dihydroimidazol- 4 ,5-dihydroimidazol-2-yl, 4 ,5-dihydroimidazol-4-yl, 4, 5-dihydroimidazol-5-yl, 2, 5-dihydroimidazol-2-yl, 2, 5-dihydroimidazol-4-yl, 2, 2-morpholinyl, 3-morpholinyl, 2-piperidinyl, 3-piperidinyl, 4-piperidinyl, 3-tetrahydropyridazinyl, 4-tetrahydropyridazinyl, 2-tetrahydropyrimidinyl, 4-tetrahydropyrimidinyl, pyrimidinyl, 2-tetrahydropyrazinyl, 1,3, 5-tetrahydrotriazin-2-yl, 1,2, 4-tetrahydrotriazin-3-yl, 1, 3-dihydrooxazin-2-yl, 1,3-dithian-2-yl, 2-tetrahydropyranyl, 1, 3-dioxolan-2-yl, 3,4,5,6tetrahydropyridin-2-yl, 4H-1, 3-thiazin-2-yl, 4H-3, 1-benzothiazin-2-yl, 1, 1-dioxo-2,3, 4,5-tetrahydrothien-2-yl, 2H-1, 4-benzothiazin-3-yl, 2H-1,4-benzoxazin-3-yl, 1, 3-dihydrooxazin-2-yl and 1, 3-dithian-2-yl; Aryl, or aryloxy. arylthio. arvicarbonyl and arylsulfonv-:.
aromatic mono- or polycyclic hydrocarbon radicals which are bonded to the skeleton directly, or (aryloxy) via an oxygen atom or (arylthio) [lacuna] a sulfur atom (arylamino) via a nitrogen atom, or (arylcarbonyl) via a carbonyl group or (arylsulfonyl) via a sulfonyl group eg. phenyl, naphthyl and phenanthrenyl, and phenyloxy, naphthyloxy and phenanthrenyloxy, respectively, and the corresponding carbonyl and sulfonyl radicals; 0050/46043 22 Hetaryl. or hetaryloxy, hetarylthio. hetarylamino, hetarylcarbonyl and hetarylsulfonvl: aromatic mono- or polycyclic radicals which, besides carbon ring members, can additionally have one to four nitrogen atoms or one to three nitrogen atoms and one oxygen or one sulfur atom or one oxygen or one sulfur atom and which are bonded directly or (hetaryloxy) via an oxygen atom or (hetarylthio) [lacuna] a sulfur atom (hetarylamino) via a nitrogen atom or (hetarylcarbonyl) via a carbonyl group or (hetarylsulfonyl) via a sulfonyl group (-S0 2 eg.
5-membered hetaryl having one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom or one oxygen or one sulfur atom: 5-membered hetaryl ring groups which, besides carbon atoms, can have one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom or one oxygen or sulfur atom as ring members, eg.
2-furyl, 3-furyl, 2-thienyl, 3-thienyl, 2-pyrrolyl, 3-pyrrolyl, 3-isoxazolyl, 4-isoxazolyl, 3-isothiazolyl, 4-isothiazolyl, 5-isothiazolyl, 3-pyrazolyl, 4-pyrazolyl, 5-pyrazolyl, 2-oxazolyl, 4-oxazolyl, 2-thiazolyl, 4-thiazolyl, 5-thiazolyl, 2-imidazolyl, 4-imidazolyl, 1,2,4-oxadiazol-3-yl, 1,2,4-oxadiazol-5-yl, 1,2,4-thiadiazol-3-yl, 1,2,4-thiadiazol-5-yl, 1,2,4-triazol- 3-yl, 1,3,4-oxadiazol-2-yl, 1,3,4-thiadiazol-2-yl and 1,3,4-triazol-2-yl; benzo-fused 5-membered hetaryl having one to three nitrogen atoms or one or two nitrogen atom and/or one oxygen or sulfur atom: 5-membered hetaryl ring groups which, besides carbon atoms, may have one to three nitrogen atoms or one to two nitrogen atoms.and one sulfur or oxygen atom or one oxygen or one sulfur atom as ring members and in which two adjacent carbon ring members or one nitrogen and one adjacent carbon ring member can be bridged by a buta-1,3-diene-1,4-diyl group; 5-membered hetaryl bonded via nitrogen and having one to four nitrogen atoms, or benzo-fused 5-membered hetaryl bonded via nitrogen and having one to three nitrogen atoms: hetaryl ring groups and benzo-fused 5-membered hetaryl ring groups as mentioned above in which two adjacent carbon ring members or one nitrogen and one adjacent carbon ring member can be bridged by a buta-1,3-diene-1,4-diyl group, these rings being bonded to the skeleton via one of the nitrogen ring members; 6-membered hetaryl having one to three, or one to four.
nitrogen atoms: 6-membered hetaryl ring groups which, besides carbon atoms, can have one to three, or one to four, nitrogen atoms as ring members, eg. 2-pyridinyl, 3-pyridinyl, 0050/46043 23 4-pyridinyl, 3-pyridazinyl, 4-pyridazinyl, 2-pyrimidinyl, 4-pyrimidinyl, 5-pyrimidinyl, 2-pyrazinyl, 1,3,5-triazin-2-yl, 1,2,4-triazin-3-yl and 1,2,4,5-tetrazin-3-yl; benzo-fused 6-membered hetaryl having one to four nitrogen atoms: 6-membered hetaryl ring groups in which two adjacent carbon ring members can be bridged by a buta-1,3-diene- 1,4-diyl group, eg. quinoline, isoquinoline, quinazoline and quinoxaline, and the corresponding oxy, thio, carbonyl or sulfonyl groups.
The term "partially or fully halogenated" is to express that some or all of the hydrogen atoms in groups which are thus characterized can be replaced by identical or different halogen atoms as mentioned above.
With a view to their biological action, preferred compounds of the formula I are those where Y is oxygen and R 1 is methyl.
Furthermore, preferred compounds of the formula I are those where X is NOCH 3 and Y is NR or oxygen.
Equally preferred compounds of the formula I are those where X is NOCH 3 and Y is NR and R is hydrogen or methyl.
Equally preferred compounds of the formula I are those where X is NOCH 3 and Y is NR and R 1 is hydrogen or methyl.
Other preferred compounds of the formula I are those where X is
NOCH
3 and Y is NR and R and R 1 are simultaneously hydrogen or methyl.
Other preferred compounds of the formula I are those where X is
NOCH
3 and Y is NR and R is hydrogen and R 1 is methyl.
Besides, preferred compounds of the formula I are those where X is NOCH 3 and Y is O.
Besides, preferred compounds of the formula I are those where X is CHOCH 3 and Y is O.
Besides, preferred compounds of the formula I are those where X is CHCH 3 and Y is 0.
Furthermore, preferred compounds I are those where R 2 is hydrogen.
Furthermore, preferred compounds I are those where R 2 is methyl.
0050/46043 24 Furthermore, preferred compounds I are those where R 2 is ethyl.
Other preferred compounds I are those where R 2 is n-propyl or isopropyl.
Furthermore, preferred compounds I are those where R 2 is trifluoromethyl.
Besides, preferred compounds I are those where R 2 is cyclopropyl.
Besides, preferred compounds of the formula I are those where R 3 is C 2
-C
6 -alkyl.
Furthermore, preferred compounds I are those where the radical R 3 has no or one branching.
Furthermore, preferred compounds I are those where R 3 is ethyl.
Furthermore, preferred compounds I are those where R 3 is isopropyl.
Equally, preferred compounds I are those where R 3 is n-propyl.
Furthermore, preferred compounds I are those where R 3 is isobutyl or n-butyl.
Besides, preferred compounds I are those where R 3 is C 5 or
C
6 -alkyl.
Other preferred compounds I are those where R 3 is C 4
-C
6 -cycloalkyl.
Besides, preferred compounds I are those where R 3 is C 2
-C
6 alkenyl.
Equally, compounds I are preferred where R 3 is vinyl, allyl, prop-1-enyl, 2-methylprop-l-enyl or iso-propenyl.
Equally, preferred compounds I are those where R 3 is C 2
-C
6 alkynyl.
Other preferred compounds I are those where R 3 is ethynyl, propargyl, l-butyn-3-yl, l-butyn-4-yl, 2-butyn-4-yl, in particular ethynyl and propargyl.
0050/46043 Furthermore, preferred compounds I are those where R 3 is substituted C-C 6 -alkyl.
Furthermore, preferred compounds I are those where R 3 is substituted or unsubstituted C 2
-C
6 -alkenyl.
Furthermore, preferred compounds I are those where R 3 is substituted or unsubstituted C 2
-C
6 -alkynyl.
Equally, preferred compounds I are those where R 3 is substituted
C
1
-C
6 -alkyl, the alkyl radical being partially or fully halogenated and/or having attached to it one to 3 of the following substituents: nitro, hydroxyl, amino, cyano, C 1
-C
6 -alkylsulfonyl,
C
1
-C
6 -alkylsulfoxyl, C 1
-C
6 -alkoxy, C 1
-C
6 -haloalkoxy, C 1
-C
6 -alkylthio, C 1 -C-alkylamino, di-C 1
-C
6 -alkylamino, C 3
-C
6 -cycloalkyl, heterocyclyl, aryl, aryloxy, hetaryl, hetaryloxy, it being possible for the cyclic radicals, in turn, to be partially or fully halogenated and/or to have attached to them one to three of the following groups: cyano, nitro, amino, aminocarbonyl, aminothiocarbonyl, C 1
-C
6 -alkyl, C 1
-C
6 -haloalkyl, C-C 6 -alkylsulfonyl, C 1
-C
6 -alkylsulfoxyl, C 1
-C
6 -alkoxy, C 1
-C
6 -haloalkoxy,
C
1
-C
6 -alkoxycarbonyl, C 1
-C
6 -alkylthio, C 1
-C
6 -alkylamino, di-C 1
-C
6 -alkylamino, Cl-C 6 -alkylaminocarbonyl, di-C 1
-C
6 -alkylaminocarbonyl, C 2
-C
6 -alkenyloxy, aryl and aryloxy.
Furthermore, preferred compounds I are those where R 3 is substituted C-C 6 -alkyl, the alkyl radical being fully or partially halogenated and/or having attached to it one to three of the following substituents: cyano, Cl-C 3 -alkoxy, phenyl, phenoxy, hetaryl, hetaryloxy, it being possible for the (hetero)aromatics to have attached to them one to three of the following groups: halogen, C 1
-C
3 -alkyl, C 1
-C
3 -haloalkyl, C 1
-C
3 -alkoxy, cyano, phenyl,
C
1
-C
3 -alkylamino and di-C 1
-C
3 -alkylamino.
Besides, preferred compounds I are those where R 3 is C 1
-C
4 -alkyl, the alkyl radical being substituted by phenyl or phenoxy and it being possible for the aromatic radical to have attached to it 1-3 of the following groups: halogen, C 1
-C
3 -alkyl, C 1
-C
3 -alkoxy, cyano, CF 3 and phenyl, in particular halogen, C 1
-C
3 -alkyl and
C
1
-C
3 -alkoxy.
Besides, preferred compounds I are those where R 3 is C 1
-C
4 -alkyl, the alkyl radical being partially or fully halogenated and/or having attached to it a cyano and/or a C 1
-C
3 -alkoxy group.
RA
7S"i 0050/46043 26 Equally, preferred compounds I are those where R 3 is Ci-C 4 -alkyl, the alkyl radical being substituted by hetaryl or hetaryloxy and it being possible for the heteroaromatic to have attached to it 1-3 of the following groups: halogen, C 1
-C
3 -alkyl, Ci-C 3 -alkoxy, cyano, CF 3 and phenyl, in particular halogen, C 1
-C
3 -alkyl and
C
1
-C
3 -alkoxy.
Other preferred compounds I are those where R 3 is substituted or unsubstituted C 2
-C
6 -alkenyl, it being possible for the alkenyl radical to be partially or fully halogenated and/or to have attached to it 1-3 of the following radicals: cyano and
C
1
-C
3 -alkoxy.
Other preferred compounds I are those where R 3 is substituted or unsubstituted C 2
-C
6 -alkenyl, it being possible for the alkenyl radical to have attached to it 1-3 halogen atoms.
Other preferred compounds I are those where R 3 is substituted or unsubstituted C 2
-C
6 -alkenyl, it being possible for the alkenyl radical to be substituted by a phenyl or hetaryl group, which can have attached to them 1-3 of the following substituents: halogen,
C
1
-C
3 -alkyl, CI-C 3 -haloalkyl, Cl-C 3 -alkoxy, cyano, C 1
-C
3 -alkylamino and di-C 1
-C
3 -alkylamino, in particular halogen, Cl-C 3 -alkyl and
C
1
-C
3 -alkoxy.
Other preferred compounds I are those where R 3 is substituted or unsubstituted C 2
-C
6 -alkenyl, it being possible for the alkenyl radical to be substituted by a phenyl group.
Other preferred compounds I are those where R 3 is substituted or unsubstituted C 2
-C
6 -alkenyl, it being possible for the alkenyl radical to be substituted by a hetaryl radical which can have attached to it 1-3 of the following substituents: halogen, C 1
-C
3 -alkyl and C 1
-C
3 -alkoxy.
Other preferred compounds I are those where R 3 is substituted or unsubstituted C 2
-C
6 -alkenyl, it being possible for the alkenyl radical to be substituted by a hetaryl radical.
Other preferred compounds I are those where R 3 is substituted or unsubstituted C 2
-C
6 -alkynyl, it being possible for the alkynyl radical to have attached to it 1-3 of the following groups: halogen, hydroxyl, amino, C 1
-C
3 -alkoxy, Cl-C 3 -alkylthio, Cl-C 3 -alkylamino, di-Ci-C 3 -alkylamino and phenyl, in particular halogen and alkoxy.
0050/46043 27 Other preferred compounds I are those where R 3 is substituted or unsubstituted C 2
-C
6 -alkynyl, the alkynyl radical being substituted by a phenyl radical, in particular phenylethynyl.
Furthermore, preferred compounds I are those where R 4 is in each case substituted or unsubstituted C 1
-C
6 -alkyl, C 2
-C
6 -alenyl [sic],
C
2 -C6-alynyl [sic], arylalkyl, hetarylalkyl, aryloxyalkyl, hetaryloxyalkyl, aryl or hetaryl.
Equally, preferred compounds I are those where R 4 is hydrogen.
Other preferred compounds I are those where R 4 is C 1
-C
6 -alkyl.
Furthermore, preferred compounds I are those where R 4 is methyl or ethyl.
Other preferred compounds I are those where R 4 is arylalkyl or hetarylalkyl.
Furthermore, preferred compounds I are those where R 4 is aryloxyalkyl or hetaryloxyalkyl.
Furthermore, preferred compounds I are those where R 4 is aryl or hetaryl.
Furthermore, preferred compounds I are those where R 4 is substituted or unsubstituted C 1
-C
6 -alkyl.
Furthermore, preferred compounds I are those where R 4 is substituted or unsubstituted C 2
-C
6 -alkenyl.
Other preferred compounds I are those where R 4 is substituted or unsubstituted C 2
-C
6 -alkynyl.
Besides, preferred compounds I are those where R 4 is C 1
-C
6 -alkyl, it being possible for the alkyl radical to be partially or fully halogenated and/or to have attached to it 1-3 of the following substituents: cyano, hydroxyl, amino, C 1
-C
6 -alkoxy, Ci-C 6 -haloalkoxy, Cl-C 6 -alkoxycarbonyl, C 1
-C
6 -alkylthio, Cl-C 6 -alkylamino, di-Cl-C 6 -alkylamino, aminocarbonyl,
C
1
-C
6 -alkylaminocarbonyl, di-C 1
-C
6 -alkylaminocarbonyl, alkenyloxy,
C
3
-C
6 -cycloalkyl, C 3
-C
6 -cycloalkyloxy, it being possible for the cyclic groups, in turn, to be partially or fully halogenated or to have attached to them one to three of the radicals C 1
-C
3 -alkyl or C 1
-C
3 -alkoxy.
.A RAL4 K j 0050/46043 28 Besides, preferred compounds I are those where R 4 is C 2
-C
6 -alkenyl, it being possible for the alkenyl radical to be partially or fully halogenated and/or to have attached to it 1-3 of the following substituents: cyano, hydroxyl, amino, Ci-C 6 -alkoxy, Cl-C 6 -haloalkoxy, C 1
-C
6 -alkoxycarbonyl, Cl-C 6 -alkylthio,
C
1
-C
6 -alkylamino, di-Cl-C 6 -alkylamino, aminocarbonyl,
C
1
-C
6 -alkylaminocarbonyl, di-Ci-C 6 -alkylaminocarbonyl, alkenyloxy,
C
3
-C
6 -cycloalkyl, C 3
-C
6 -cycloalkyloxy, it being possible for the cyclic groups, in turn, to be partially or fully halogenated or to have attached to them one to three of the radicals C 1
-C
3 -alkyl or Ci-C 3 -alkoxy.
Besides, preferred compounds I are those where R 4 is C 2
-C
6 -alkynyl, it being possible for the alkynyl radical to be partially or fully halogenated and/or to have attached to it 1-3 of the following substituents: cyano, hydroxyl, amino, CI-C 6 -alkoxy, Ci-C 6 -haloalkoxy, C 1
-C
6 -alkoxycarbonyl, Cl-C 6 -alkylthio,
C
1
-C
6 -alkylamino, di-Cl-C 6 -alkylamino, aminocarbonyl, Ci-C 6 -alkylaminocarbonyl, di-Cl-C 6 -alkylaminocarbonyl, alkenyloxy,
C
3
-C
6 -cycloalkyl, C 3 -C6-cycloalkyloxy, it being possible for the cyclic groups, in turn, to be partially or fully halogenated or to have attached to them one to three of the radicals Cl-C 3 -alkyl or C 1
-C
3 -alkoxy.
Besides, preferred compounds I are those where R 4 is C 2
-C
6 alkynyl, it being possible for the alkynyl radical to have attached to it 1-3 of the following substituents: halogen, cyano and C 1
-C
3 -alkoxy, in particular halogen.
Besides, preferred compounds I are those where R 4 is C 2
-C
6 alkenyl, it being possible for the alkenyl radical to have attached to it 1-3 of the following radicals: halogen, cyano and
C
1
-C
3 -alkoxy, in particular halogen.
Besides, preferred compounds I are those where R 4 is C 1
-C
6 -alkyl, it being possible for the alkyl radical to be partially or fully halogenated and/or to have attached to it 1-3 of the following radicals: Ci-C 3 -alkoxy and cyano.
Other preferred compounds I are those where R 4 is C 2
-C
6 -alkenyl.
Other preferred compounds I are those where R 4 is C 2
-C
6 -alkynyl, in particular propargyl.
Other preferred compounds I are those where R 4 is propargyl.
0050/46043 29 Furthermore, preferred compounds I are those where R 4 is trans-3-chloroprop-2-enyl.
Furthermore, preferred compounds I are those where R 4 is 2-methoxyethyl.
Furthermore, preferred compounds I are those where R 4 is allyl.
Besides, preferred compounds of the formula I are those where the substituents are selected from a combination of the abovementioned preferred substituents.
Preferred compounds of the formulae I.1 to 1.4 are, with a view to their use, in particular those compiled in the tables which follow.
R
4 0N NOCH 2 OCH (I.1) 3 C=CH
CO
2
CH
3
R
4 0N
NOCH
R0 NOCH C CH 3 (1.2)
C=CH-
R
3
I
CO
2
CH
3
R
4 ON^ R R SR
NOCH
2 OCH 3 (1.3)
R
3 C=N
CO
2
CH
3
R
2 4 0N NOCH(
OCH
3 (1.4)
C=N
R3
I
O=CNHCH3 0050/46043 Table 1 Compounds of the general formula I.1 where R 3 is ethyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 2 Compounds of the general formula 1.2 where R 3 is ethyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 3 Compounds of the general formula 1.3 where R 3 is ethyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 4 Compounds of the general formula 1.4 where R 3 is ethyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table Compounds of the general formula I.1 where R 3 is n-propyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 6 Compounds of the general formula 1.2 where R 3 is n-propyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 7 Compounds of the general formula 1.3 where R 3 is n-propyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 8 Compounds of the general formula 1.4 where R 3 is n-propyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 9 Compounds of the general formula I.1 where R 3 is iso-propyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
0050/46043 Table Compounds of the general formula 1.2 where R 3 is iso-propyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 11 Compounds of the general formula 1.3 where R 3 is iso-propyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 12 Compounds of the general formula 1.4 where R 3 is iso-propyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 13 Compounds of the general formula I.1 where R 3 is n-butyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 14 Compounds of the general formula 1.2 where R 3 is n-butyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table Compounds of the general formula 1.3 where R 3 is n-butyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 16 Compounds of the general formula 1.4 where R 3 is n-butyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 17 Compounds of the general formula I.1 where R 3 is iso-butyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 18 Compounds of the general formula 1.2 where R 3 is iso-butyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
0050/46043 Table 19 Compounds of the general formula 1.3 where R 3 is iso-butyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table Compounds of the general formula 1.4 where R 3 is iso-butyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 21 Compounds of the general formula I.1 where R 3 is sec-butyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 22 Compounds of the general formula 1.2 where R 3 is sec-butyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 23 Compounds of the general formula 1.3 where R 3 is sec-butyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 24 Compounds of the general formula 1.4 where R 3 is sec-butyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table Compounds of the general formula I.1 where R 3 is cyclobutyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 26 Compounds of the general formula 1.2 where R 3 is cyclobutyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 27 Compounds of the general formula 1.3 where R 3 the combination of the substituents R 2 and R 4 corresponds to in each case one line of Table is cyclobutyl and for a compound
A.
0050/46043 Table 28 Compounds of the general formula 1.4 where R 3 the combination of the substituents R 2 and R 4 corresponds to in each case one line of Table is for
A.
Table 29 Compounds of the general formula I.1 where R 3 is combination of the substituents R 2 and R 4 for a c corresponds to in each case one line of Table A.
Table Compounds of the general formula 1.2 where R 3 is combination of the substituents R 2 and R 4 for a c corresponds to in each case one line of Table A.
cyclobutyl and a compound n-pentyl and the :ompound n-pentyl and the :ompound Table 31 Compounds of the general formula 1.3 where R 3 is n-pentyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 32 Compounds of the general formula 1.4 where R 3 is n-pentyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 33 Compounds of the general formula I.1 where R 3 is cyclopentyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 34 Compounds of the general formula 1.2 where R 3 is cyclopentyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table Compounds of the general formula 1.3 where R 3 is cyclopentyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 36 Compounds of the general formula 1.4 where R 3 is cyclopentyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
0050/46043 Table 37 Compounds of the general formula I.1 where R 3 is n-hexyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 38 Compounds of the general formula 1.2 where R 3 is n-hexyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 39 Compounds of the general formula 1.3 where R 3 is n-hexyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table Compounds of the general formula 1.4 where R 3 is n-hexyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 41 Compounds of the general formula I.1 where R 3 is cyclohexyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 42 Compounds of the general formula 1.2 where R 3 is cyclohexyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 43 Compounds of the general formula 1.3 where R 3 is cyclohexyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 44 Compounds of the general formula 1.4 where R 3 is cyclohexyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table Compounds of the general formula I.1 where R 3 is ethenyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
0050/46043 Table 46 Compounds of the general formula 1.2 where R 3 combination of the substituents R 2 and R 4 for corresponds to in each case one line of Table is a
A.
Table 47 Compounds of the general formula 1.3 where R 3 is combination of the substituents R 2 and R 4 for a corresponds to in each case one line of Table A.
Table 48 Compounds of the general formula 1.4 where R 3 is combination of the substituents R 2 and R 4 for a corresponds to in each case one line of Table A.
ethenyl and the compound ethenyl and the compound ethenyl and the compound Table 49 Compounds of the general formula I.1 where R 3 is propen-2-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table Compounds of the general formula 1.2 where R 3 is propen-2-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 51 Compounds of the general formula 1.3 where R 3 is propen-2-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 52 Compounds of the general formula 1.4 where R 3 is propen-2-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 53 Compounds of the general formula I.1 where R 3 the combination of the substituents R 2 and R 4 corresponds to in each case one line of Table Table 54 Compounds of the general formula 1.2 where R 3 the combination of the substituents R 2 and R 4 corresponds to in each case one line of Table is propen-1-yl and for a compound
A.
is propen-1-yl and for a compound
A.
0050/46043 Table Compounds of the general formula 1.3 where R 3 is propen-1-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 56 Compounds of the general formula 1.4 where R 3 is propen-1-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 57 Compounds of the general formula I.1 where R 3 is isobuten-1-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 58 Compounds of the general formula 1.2 where R 3 is isobuten-1-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 59 Compounds of the general formula 1.3 where R 3 is isobuten-1-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table Compounds of the general formula 1.4 where R 3 is isobuten-1-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 61 Compounds of the general formula I.1 where R 3 is propen-3-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 62 Compounds of the general formula 1.2 where R 3 is propen-3-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 63 Compounds of the general formula 1.3 where R 3 is propen-3-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
0050/46043 Table 64 Compounds of the general formula 1.4 where R 3 is propen-3-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table Compounds of the general formula I.1 where R 3 is isobuten-3-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 66 Compounds of the general formula 1.2 where R 3 is isobuten-3-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 67 Compounds of the general formula 1.3 where R 3 is isobuten-3-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 68 Compounds of the general formula 1.4 where R 3 is isobuten-3-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 69 Compounds of the general formula I.1 where R 3 is but-2-en-l-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table Compounds of the general formula 1.2 where R 3 is but-2-en-l-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 71 Compounds of the general formula 1.3 where R 3 is but-2-en-l-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 72 Compounds of the general formula 1.4 where R 3 the combination of the substituents R 2 and R 4 corresponds to in each case one line of Table is but-2-en-l-yl and for a compound
A.
0050/46043 Table 73 Compounds of the general formula I.1 where R 3 is but-3-en-l-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 74 Compounds of the general formula 1.2 where R 3 is but-3-en-l-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table Compounds of the general formula 1.3 where R 3 is but-3-en-l-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 76 Compounds of the general formula 1.4 where R 3 is but-3-en-l-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 77 Compounds of the general formula I.1 where R 3 is ethynyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 78 Compounds of the general formula 1.2 where R 3 is ethynyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 79 Compounds of the general formula 1.3 where R 3 is ethynyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table Compounds of the general formula 1.4 where R 3 is ethynyl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 81 Compounds of the general formula I.1 where R 3 is prop-l-yn-3-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
0050/46043 39 Table 82 Compounds of the general formula 1.2 where R 3 is prop-l-yn-3-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 83 Compounds of the general formula 1.3 where R 3 is prop-l-yn-3-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 84 Compounds of the general formula 1.4 where R 3 is prop-l-yn-3-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table Compounds of the general formula I.1 where R 3 is but-l-yn-3-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 86 Compounds of the general formula 1.2 where R 3 is but-l-yn-3-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 87 Compounds of the general formula 1.3 where R 3 is but-l-yn-3-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 88 Compounds of the general formula 1.4 where R 3 is but-l-yn-3-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 89 Compounds of the general formula I.1 where R 3 is but-2-yn-l-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table Compounds of the general formula 1.2 where R 3 the combination of the substituents R 2 and R 4 corresponds to in each case one line of Table is but-2-yn-l-yl and for a compound
A.
0050/46043 Table 91 Compounds of the general formula 1.3 where R 3 is but-2-yn-l-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 92 Compounds of the general formula 1.4 where R 3 is but-2-yn-l-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 93 Compounds of the general formula I.1 where R 3 is but-3-yn-l-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 94 Compounds of the general formula 1.2 where R 3 is but-3-yn-l-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table Compounds of the general formula 1.3 where R 3 is but-3-yn-l-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 96 Compounds of the general formula 1.4 where R 3 is but-3-yn-l-yl and the combination of the substituents R 2 and R 4 for a compound corresponds to in each case one line of Table A.
Table 97 Compounds of the general formula I.1 where R 2 is methyl and R 4 is hydrogen and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 98 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is hydrogen and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 99 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is hydrogen and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 41 Table 100 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is hydrogen and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 101 Compounds of the general formula I.1 where R 2 is methyl and R 4 is methyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 102 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is methyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 103 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is methyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 104 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is methyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 105 Compounds of the general formula I.1 where R 2 is methyl and R 4 is ethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 106 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is ethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 107 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is ethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 108 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is ethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 42 Table 109 Compounds of the general formula I.1 where R 2 is methyl and R 4 is n-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 110 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is n-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 111 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is n-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 112 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is n-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 113 Compounds of the general formula I.1 where R 2 is iso-propyl and the substituent R 3 for a compound each case one line of Table B.
Table 114 Compounds of the general formula 1.2 where R 2 is iso-propyl and the substituent R 3 for a compound each case one line of Table B.
Table 115 Compounds of the general formula 1.3 where R 2 is iso-propyl and the substituent R 3 for a compound each case one line of Table B.
methyl and R 4 is corresponds to in methyl and R 4 is corresponds to in methyl and R 4 is corresponds to in Table 116 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is iso-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 117 Compounds of the general formula I.1 where R 2 is methyl and R 4 is n-butyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 43 Table 118 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is n-butyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 119 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is n-butyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 120 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is n-butyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 121 Compounds sec-butyl each case Table 122 Compounds sec-butyl each case Table 123 Compounds sec-butyl each case Table 124 Compounds sec-butyl each case Table 125 Compounds iso-butyl each case Table 126 Compounds iso-butyl each case of the general formula and the substituent R 3 one line of Table B.
of the general formula and the substituent R 3 one line of Table B.
of the general formula and the substituent R 3 one line of Table B.
of the general formula and the substituent R 3 one line of Table B.
of the general formula and the substituent R 3 one line of Table B.
of the general formula and the substituent R 3 one line of Table B.
I.1 where R 2 is methyl and for a compound corresponds 1.2 where R 2 is methyl and R 4 is for a compound corresponds to in 1.3 where R 2 is methyl and R 4 is for a compound corresponds to in 1.4 where R 2 is methyl and R 4 is for a compound corresponds to in I.1 where R 2 is methyl and R 4 is for a compound corresponds to in 1.2 where R 2 is methyl and R 4 is for a compound corresponds to in 0050/46043 Table 127 Compounds iso-butyl each case Table 128 Compounds iso-butyl each case of the general formula 1.3 where R 2 is methyl and R 4 is and the substituent R 3 for a compound corresponds to in one line of Table B.
of the general formula 1.4 where R 2 is methyl and R 4 is and the substituent R 3 for a compound corresponds to in one line of Table B.
Table 129 Compounds of the general formula I.1 where R 2 is methyl and R 4 is tert-butyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 130 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is tert-butyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 131 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is tert-butyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 132 Compounds of the general formula 1.4 where R 2 is tert-butyl and the substituent R 3 for a compound each case one line of Table B.
methyl and R 4 is corresponds to in Table 133 Compounds of the general formula I.1 where R 2 is methyl and R 4 is n-pentyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 134 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is n-pentyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 135 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is n-pentyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 Table 136 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is n-pentyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 137 Compounds of the general formula I.1 where R 2 is iso-pentyl and the substituent R 3 for a compound each case one line of Table B.
methyl and R 4 is corresponds to in Table 138 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is iso-pentyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 139 Compounds of the general formula 1.3 where R 2 is iso-pentyl and the substituent R 3 for a compound each case one line of Table B.
Table 140 Compounds of the general formula 1.4 where R 2 is iso-pentyl and the substituent R 3 for a compound each case one line of Table B.
Table 141 Compounds of the general formula I.1 where R 2 is neo-pentyl and the substituent R 3 for a compound each case one line of Table B.
Table 142 Compounds of the general formula 1.2 where R 2 is neo-pentyl and the substituent R 3 for a compound each case one line of Table B.
methyl and R 4 is corresponds to in methyl and R 4 is corresponds to in methyl and R 4 is corresponds to in methyl and R 4 is corresponds to in Table 143 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is neo-pentyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 144 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is neo-pentyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 Table 145 Compounds of the general formula I.1 2-methylbutyl and the substituent R 3 in each case one line of Table B.
Table 146 Compounds of the general formula 1.2 2-methylbutyl and the substituent R 3 in each case one line of Table B.
Table 147 Compounds of the general formula 1.3 2-methylbutyl and the substituent R 3 in each case one line of Table B.
Table 148 Compounds of the general formula 1.4 2-methylbutyl and the substituent R 3 in each case one line of Table B.
Table 149 Compounds of the general formula I.1 1-methylbutyl and the substituent R 3 in each case one line of Table B.
Table 150 Compounds of the general formula 1.2 1-methylbutyl and the substituent R 3 in each case one line of Table B.
Table 151 Compounds of the general formula 1.3 1-methylbutyl and the substituent R 3 in each case one line of Table B.
Table 152 Compounds of the general formula 1.4 1-methylbutyl and the substituent R 3 in each case one line of Table B.
where R 2 is methyl and R 4 is for a compound corresponds to where for a
R
2 is methyl and R 4 is compound corresponds to where R 2 is methyl and R 4 is for a compound corresponds to where for a
R
2 is methyl and R 4 is compound corresponds to where R 2 is methyl and R 4 is for a compound corresponds to where R 2 is methyl and R 4 is for a compound corresponds to where for a
R
2 is methyl and R 4 is compound corresponds to where R 2 is methyl and R 4 is for a compound corresponds to Table 153 Compounds of the general formula I.1 where R 2 is methyl and R 4 is pentan-3-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 47 Table 154 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is pentan-3-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 155 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is pentan-3-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 156 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is pentan-3-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 157 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 3-methylbutan-2-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 158 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 3-methylbutan-2-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 159 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 3-methylbutan-2-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 160 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 3-methylbutan-2-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 161 Compounds of the general formula I.1 where R 2 2-methylbutan-2-yl and the substituent R 3 for corresponds to in each case one line of Table Table 162 Compounds of the general formula 1.2 where R 2 2-methylbutan-2-yl and the substituent R 3 for corresponds to in each case one line of Table is methyl and R 4 is a compound
B.
is methyl and R 4 is a compound
B.
0050/46043 Table 163 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 2-methylbutan-2-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 164 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 2-methylbutan-2-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 165 Compounds of the general formula hexyl and the substituent R 3 for case one line of Table B.
Table 166 Compounds of the general formula hexyl and the substituent R 3 for case one line of Table B.
Table 167 Compounds of the general formula hexyl and the substituent R 3 for case one line of Table B.
I.1 where R 2 is methyl and R 4 is a compound corresponds to in each 1.2 where R 2 is methyl and R 4 is a compound corresponds to in each 1.3 where R 2 is methyl and R 4 is a compound corresponds to in each Table 168 Compounds of the general formula 1.4 where R 2 is methyl hexyl and the substituent R 3 for a compound corresponds case one line of Table B.
Table 169 Compounds of the general formula I.1 where R 2 is methyl 3,3-dimethylbutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
and R 4 is to in each and R 4 is Table 170 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 3,3-dimethylbutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 171 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 3,3-dimethylbutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 49 Table 172 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 3,3-dimethylbutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 173 Compounds of 2-ethylbutyl in each case Table 174 Compounds of 2-ethylbutyl in each case Table 175 Compounds of 2-ethylbutyl in each case Table 176 Compounds of 2-ethylbutyl in each case Table 177 Compounds of the and one the and one the and one the and one general formula I.1 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
general formula 1.2 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
general formula 1.3 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
general formula 1.4 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
the general formula I.1 where R 2 is methyl and R 4 is 4-methylpentyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 178 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 4-methylpentyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 179 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 4-methylpentyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 180 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 4-methylpentyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
I
0050/46043 Table 181 Compounds of the general formula I.1 where R 2 is methyl and R 4 is cyclopropylmethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 182 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is cyclopropylmethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 183 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is cyclopropylmethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 184 Compounds of the general formula 1.4 where R 2 is methyl cyclopropylmethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
and R 4 is Table 185 Compounds of the general formula I.1 where R 2 is 2-cyclopropyleth-l-yl and the substituent R 3 for corresponds to in each case one line of Table B.
Table 186 Compounds of the general formula 1.2 where R 2 is 2-cyclopropyleth-l-yl and the substituent R 3 for corresponds to in each case one line of Table B.
Table 187 Compounds of the general formula 1.3 where R 2 is 2-cyclopropyleth-l-yl and the substituent R 3 for corresponds to in each case one line of Table B.
Table 188 Compounds of the general formula 1.4 where R 2 is 2-cyclopropyleth-l-yl and the substituent R 3 for corresponds to in each case one line of Table B.
methyl and R 4 is a compound methyl and R 4 is a compound methyl and R 4 is a compound methyl and R 4 is a compound Table 189 Compounds of the general formula I.1 where R 2 is methyl and R 4 is cyclohexylmethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 Table 190 Compounds of the general cyclohexylmethyl and the to in each case one line Table 191 Compounds of the general cyclohexylmethyl and the to in each case one line Table 192 Compounds of the general cyclohexylmethyl and the to in each case one line formula 1.2 substituent of Table B.
formula 1.3 substituent of Table B.
formula 1.4 substituent of Table B.
where R 2
R
3 for a where R 2
R
3 for a is methyl and R 4 is compound corresponds is methyl and R 4 is compound corresponds where R 2 is methyl and R 4 is
R
3 for a compound corresponds Table 193 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 2-cyclohexyleth-l-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 194 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 2-cyclohexyleth-l-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 195 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 2-cyclohexyleth-l-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 196 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 2-cyclohexyleth-l-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 197 Compounds of the general formula I.1 where R 2 is methyl and R 4 is cyclopropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 198 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is cyclopropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 52 Table 199 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is cyclopropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 200 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is cyclopropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 201 Compounds of the general formula I.1 where R 2 is methyl and R 4 is cyclopentyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 202 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is cyclopentyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 203 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is cyclopentyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 204 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is cyclopentyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 205 Compounds of the general formula I.1 where R 2 is methyl and R 4 is cyclohexyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 206 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is cyclohexyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 207 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is cyclohexyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 53 Table 208 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is cyclohexyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 209 Compounds of the general formula I.1 where R 2 is methyl and R 4 is difluoromethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 210 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is difluoromethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 211 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is difluoromethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 212 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is difluoromethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 213 Compounds of the general formula I.1 2-fluoroethyl and the substituent R 3 in each case one line of Table B.
Table 214 Compounds of the general formula 1.2 2-fluoroethyl and the substituent R 3 in each case one line of Table B.
Table 215 Compounds of the general formula 1.3 2-fluoroethyl and the substituent R 3 in each case one line of Table B.
Table 216 Compounds of the general formula 1.4 2-fluoroethyl and the substituent R 3 in each case one line of Table B.
where R 2 is methyl and R 4 is for a compound corresponds to where for a
R
2 is methyl and R 4 is compound corresponds to where R 2 is methyl and R 4 is for a compound corresponds to where R 2 is methyl and R 4 is for a compound corresponds to 0050/46043 54 Table 217 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 3-fluoropropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 218 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 3-fluoropropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 219 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 3-fluoropropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 220 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 3-fluoropropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 221 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 2,2-difluoroethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 222 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 2,2-difluoroethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 223 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 2,2-difluoroethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 224 Compounds of the general formula I.4 where R 2 is methyl and R 4 is 2,2-difluoroethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 225 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 2,2,2-trifluoroethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 Table 226 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 2,2,2-trifluoroethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 227 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 2,2,2-trifluoroethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 228 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 2,2,2-trifluoroethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 229 Compounds of 2-bromoethyl in each case Table 230 Compounds of 2-bromoethyl in each case Table 231 Compounds of 2-bromoethyl in each case Table 232 Compounds of 2-bromoethyl in each case Table 233 Compounds of the and one the and one the and one the and one general formula I.1 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
general formula 1.2 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
general formula 1.3 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
general formula 1.4 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
the general formula I.1 where R 2 is methyl and R 4 is 3-bromopropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 234 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 3-bromopropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
R A3 0 l T ^L 0 7 0050/46043 56 Table 235 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 3-bromopropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 236 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 3-bromopropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 237 Compounds of 4-bromobutyl in each case Table 238 Compounds of 4-bromobutyl in each case Table 239 Compounds of 4-bromobutyl in each case Table 240 Compounds of 4-bromobutyl in each case Table 241 Compounds of the and one the and one the and one the and one general formula I.1 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
general formula 1.2 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
general formula 1.3 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
general formula 1.4 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
the general formula I.1 where R 2 is methyl and R 4 is 2-iodoethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 242 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 2-iodoethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 243 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 2-iodoethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 57 Table 244 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 2-iodoethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 245 Compounds of the general formula I.1 2-chloroethyl and the substituent R 3 in each case one line of Table B.
Table 246 Compounds of the general formula 1.2 2-chloroethyl and the substituent R 3 in each case one line of Table B.
Table 247 Compounds of the general formula 1.3 2-chloroethyl and the substituent R 3 in each case one line of Table B.
Table 248 Compounds of the general formula 1.4 2-chloroethyl and the substituent R 3 in each case one line of Table B.
where for a
R
2 is methyl and R 4 is compound corresponds to where R 2 is methyl and R 4 is for a compound corresponds to where for a
R
2 is methyl and R 4 is compound corresponds to where R 2 is methyl and R 4 is for a compound corresponds to Table 249 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 3-chloropropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 250 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 3-chloropropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 251 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 3-chloropropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 252 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 3-chloropropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 Table 253 Compounds of the general formula I.1 4-chlorobutyl and the substituent R 3 in each case one line of Table B.
Table 254 Compounds of the general formula 1.2 4-chlorobutyl and the substituent R 3 in each case one line of Table B.
Table 255 Compounds of the general formula 1.3 4-chlorobutyl and the substituent R 3 in each case one line of Table B.
Table 256 Compounds of the general formula 1.4 4-chlorobutyl and the substituent R 3 in each case one line of Table B.
where R 2 is methyl and R 4 is for a compound corresponds to where for a
R
2 is methyl and R 4 is compound corresponds to where R 2 is methyl and R 4 is for a compound corresponds to where for a
R
2 is methyl and R 4 is compound corresponds to Table 257 Compounds of the general formula I.1 where R 2 is methyl and R 4 is cyanomethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 258 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is cyanomethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 259 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is cyanomethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 260 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is cyanomethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 261 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 2-cyanoethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 Table 262 Compounds of 2-cyanoethyl in each case Table 263 Compounds of 2-cyanoethyl in each case Table 264 Compounds of 2-cyanoethyl in each case Table 265 Compounds of the and one the and one general formula 1.2 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
general formula 1.3 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
general formula 1.4 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
the and one the general formula I.1 where R 2 is methyl and R 4 is 3-cyanopropyl and the substituent R 3 in each case one line of Table B.
Table 266 Compounds of the general formula 1.2 3-cyanopropyl and the substituent R 3 in each case one line of Table B.
Table 267 Compounds of the general formula 1.3 3-cyanopropyl and the substituent R 3 in each case one line of Table B.
Table 268 Compounds of the general formula 1.4 3-cyanopropyl and the substituent R 3 in each case one line of Table B.
for a compound corresponds to where R 2 is methyl and R 4 is for a compound corresponds to where R 2 is methyl and R 4 is for a compound corresponds to where R 2 is methyl and R 4 is for a compound corresponds to Table 269 Compounds of 4-cyanobutyl in each case Table 270 Compounds of 4-cyanobutyl in each case the and one the and one general formula I.1 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
general formula 1.2 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
w 0050/46043 Table 271 Compounds of 4-cyanobutyl in each case Table 272 Compounds of 4-cyanobutyl in each case Table 273 Compounds of 6-cyanohexyl in each case Table 274 Compounds of 6-cyanohexyl in each case Table 275 Compounds of 6-cyanohexyl in each case Table 276 Compounds of 6-cyanohexyl in each case Table 277 Compounds of the and one the and one the and one the and one the and one the and one general formula 1.3 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
general formula 1.4 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
general formula I.1 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
general formula 1.2 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
general formula 1.3 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
general formula 1.4 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
the general formula I.1 where R 2 is methyl and R 4 is 2-methoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 278 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 2-methoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 279 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 2-methoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
M- M 0050/46043 61 Table 280 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 2-methoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 281 Compounds of the general formula I.1 2-ethoxyethyl and the substituent R 3 in each case one line of Table B.
Table 282 Compounds of the general formula 1.2 2-ethoxyethyl and the substituent R 3 in each case one line of Table B.
Table 283 Compounds of the general formula I.3 2-ethoxyethyl and the substituent R 3 in each case one line of Table B.
Table 284 Compounds of the general formula 1.4 2-ethoxyethyl and the substituent R 3 in each case one line of Table B.
where R 2 is methyl and R 4 is for a compound corresponds to where for a
R
2 is methyl and R 4 is compound corresponds to where R 2 is methyl and R 4 is for a compound corresponds to where for a
R
2 is methyl and R 4 is compound corresponds to Table 285 Compounds of the general formula I.1 where R 2 is methyl 2-isopropoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
and R 4 is Table 286 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 2-isopropoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 287 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 2-isopropoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 288 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 2-isopropoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 62 Table 289 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 3-methoxypropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 290 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 3-methoxypropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 291 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 3-methoxypropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 292 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 3-methoxypropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 293 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 3-ethoxypropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 294 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 3-ethoxypropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 295 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 3-ethoxypropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 296 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 3-ethoxypropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 297 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 3-isopropoxypropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 Table 298 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 3-isopropoxypropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 299 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 3-isopropoxypropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 300 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 3-isopropoxypropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 301 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 4-methoxybutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 302 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 4-methoxybutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 303 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 4-methoxybutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 304 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 4-methoxybutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 305 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 4-ethoxybutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 306 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 4-ethoxybutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 64 Table 307 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 4-ethoxybutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 308 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 4-ethoxybutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 309 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 4-isopropoxybutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 310 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 4-isopropoxybutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 311 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 4-isopropoxybutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 312 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 4-isopropoxybutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 313 Compounds of the general formula I.1 where R 2 is methyl and R 4 is prop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 314 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is prop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 315 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is prop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
J k 4 0050/46043 Table 316 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is prop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 317 Compounds of the general formula I.1 where R 2 is methyl and R 4 is cis-but-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 318 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is cis-but-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 319 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is cis-but-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 320 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is cis-but-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 321 Compounds of the general trans-but-2-enyl and the to in each case one line Table 322 Compounds of the general trans-but-2-enyl and the to in each case one line Table 323 Compounds of the general trans-but-2-enyl and the to in each case one line Table 324 Compounds of the general trans-but-2-enyl and the to in each case one line formula I.1 substituent of Table B.
formula 1.2 substituent of Table B.
formula 1.3 substituent of Table B.
formula 1.4 substituent of Table B.
where R 2
R
3 for a where R 2
R
3 for a is methyl and R 4 is compound corresponds is methyl and R 4 is compound corresponds where R 2
R
3 for a is methyl and R 4 is compound corresponds where R 2 is methyl and R 4 is
R
3 for a compound corresponds 0050/46043 Table 325 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 3-methylbut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 326 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 3-methylbut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 327 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 3-methylbut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 328 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 3-methylbut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 329 Compounds of the general formula I.1 where R 2 is 2-methylprop-2-enyl and the substituent R 3 for a corresponds to in each case one line of Table B.
Table 330 Compounds of the general formula 1.2 where R 2 is 2-methylprop-2-enyl and the substituent R 3 for a corresponds to in each case one line of Table B.
Table 331 Compounds of the general formula 1.3 where R 2 is 2-methylprop-2-enyl and the substituent R 3 for a corresponds to in each case one line of Table B.
Table 332 Compounds of the general formula 1.4 where R 2 is 2-methylprop-2-enyl and the substituent R 3 for a corresponds to in each case one line of Table B.
Table 333 Compounds of the general formula I.1 where R 2 is but-3-enyl and the substituent R 3 for a compound each case one line of Table B.
methyl and R 4 is compound methyl and R 4 is compound methyl and R 4 is compound methyl and R 4 is compound methyl and R 4 is corresponds to in r 0050/46043 67 Table 334 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is but-3-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 335 Compounds of the general formula 1.3 where R 2 is but-3-enyl and the substituent R 3 for a compound each case one line of Table B.
Table 336 Compounds of the general formula 1.4 where R 2 is but-3-enyl and the substituent R 3 for a compound each case one line of Table B.
methyl and R 4 is corresponds to in methyl and R 4 is corresponds to in Table 337 Compounds of the general formula 1.1 where R 2 is methyl and R 4 is cis-3-chloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 338 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is cis-3-chloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 339 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is cis-3-chloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 340 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is cis-3-chloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 341 Compounds of the general formula I.1 where R 2 trans-3-chloroprop-2-enyl and the substituent corresponds to in each case one line of Table Table 342 Compounds of the general formula 1.2 where R 2 trans-3-chloroprop-2-enyl and the substituent corresponds to in each case one line of Table methyl and R 4 is for a compound methyl and R 4 is for a compound 0050/46043 Table 343 Compounds of the general formula 1.3 where R 2 is trans-3-chloroprop-2-enyl and the substituent R 3 corresponds to in each case one line of Table B.
Table 344 Compounds of the general formula 1.4 where R 2 is trans-3-chloroprop-2-enyl and the substituent R 3 corresponds to in each case one line of Table B.
Table 345 Compounds of the general formula I.1 where R 2 is 2-chloroprop-2-enyl and the substituent R 3 for a corresponds to in each case one line of Table B.
Table 346 Compounds of the general formula 1.2 where R 2 is 2-chloroprop-2-enyl and the substituent R 3 for a corresponds to in each case one line of Table B.
Table 347 Compounds of the general formula 1.3 where R 2 is 2-chloroprop-2-enyl and the substituent R 3 for a corresponds to in each case one line of Table B.
Table 348 Compounds of the general formula 1.4 where R 2 is 2-chloroprop-2-enyl and the substituent R 3 for a corresponds to in each case one line of Table B.
methyl and R 4 is for a compound methyl and R 4 is for a compound methyl and R 4 is compound methyl and R 4 is compound methyl and R 4 is compound methyl and R 4 is compound Table 349 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 3,3-dichloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 350 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 3,3-dichloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 351 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 3,3-dichloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
I
0050/46043 69 Table 352 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 3,3-dichloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 353 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 2,3,3-trichloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 354 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 2,3,3-trichloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 355 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 2,3,3-trichloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 356 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 2,3,3-trichloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 357 Compounds of the general formula I.1 where R 2 is methyl and R 4 is cis-2,3-dichloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 358 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is cis-2,3-dichloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 359 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is cis-2,3-dichloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 360 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is cis-2,3-dichloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
F 0050/46043 Table 361 Compounds of the general formula I.1 where R 2 is methyl and R 4 is trans-2,3-dichloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 362 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is trans-2,3-dichloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 363 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is trans-2,3-dichloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 364 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is trans-2,3-dichloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 365 Compounds of the general formula I.1 where R 2 is methyl and R 4 is cis-3-bromoprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 366 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is cis-3-bromoprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 367 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is cis-3-bromoprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 368 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is cis-3-bromoprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 369 Compounds of the general formula I.1 where R 2 is methyl and R 4 is trans-3-bromoprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 Table 370 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is trans-3-bromoprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 371 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is trans-3-bromoprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 372 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is trans-3-bromoprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 373 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 2-bromoprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 374 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 2-bromoprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 375 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 2-bromoprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 376 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 2-bromoprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 377 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 3,3-dibromoprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 378 Compounds of the general formula 1.2 where R 2 3,3-dibromoprop-2-enyl and the substituent R 3 corresponds to in each case one line of Table is methyl and R 4 is for a compound
B.
0050/46043 Table 379 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 3,3-dibromoprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 380 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 3,3-dibromoprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 381 Compounds of the general formula I.1 where R 2 is 2,3,3-tribromoprop-2-enyl and the substituent R 3 corresponds to in each case one line of Table B.
Table 382 Compounds of the general formula 1.2 where R 2 is 2,3,3-tribromoprop-2-enyl and the substituent R 3 corresponds to in each case one line of Table B.
methyl and R 4 is for a compound methyl and R 4 is for a compound Table 383 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 2,3,3-tribromoprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 384 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 2,3,3-tribromoprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 385 Compounds of the general formula I.1 where R 2 is methyl and R 4 is cis-2,3-dibromoprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 386 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is cis-2,3-dibromoprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 387 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is cis-2,3-dibromoprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
w 0050/46043 Table 388 Compounds of the general formula 1.4 where R 2 is methyl cis-2,3-dibromoprop-2-enyl and the substituent R 3 for a corresponds to in each case one line of Table B.
and R 4 is compound Table 389 Compounds of the general formula I.1 trans-2,3-dibromoprop-2-enyl and the corresponds to in each case one line Table 390 Compounds of the general formula 1.2 trans-2,3-dibromoprop-2-enyl and the corresponds to in each case one line Table 391 Compounds of the general formula 1.3 trans-2,3-dibromoprop-2-enyl and the corresponds to in each case one line Table 392 Compounds of the general formula 1.4 trans-2,3-dibromoprop-2-enyl and the corresponds to in each case one line Table 393 Compounds of the general formula I.1 where
R
2 is substituent of Table B.
methyl
R
3 for and R 4 is a compound where R 2 is methyl and R 4 is substituent R 3 for a compound of Table B.
where
R
2 is substituent of Table B.
where R 2 is substituent of Table B.
methyl
R
3 for and R 4 is a compound methyl and R 4 is
R
3 for a compound where R 2 is methyl and R 4 is trans-2-chlorobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 394 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is trans-2-chlorobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 395 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is trans-2-chlorobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 396 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is trans-2-chlorobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 Table 397 Compounds of the general formula I.1 where R 2 is methyl and R 4 is cis-2-chlorobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 398 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is cis-2-chlorobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 399 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is cis-2-chlorobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 400 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is cis-2-chlorobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 401 Compounds of the general formula I.1 where R 2 is methyl and R 4 is trans-3-chlorobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 402 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is trans-3-chlorobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 403 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is trans-3-chlorobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 404 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is trans-3-chlorobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 405 Compounds of the general formula I.1 where R 2 cis-3-chlorobut-2-enyl and the substituent R 3 corresponds to in each case one line of Table is methyl and R 4 is for a compound
B.
M I
M
0050/46043 Table 406 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is cis-3-chlorobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 407 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is cis-3-chlorobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 408 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is cis-3-chlorobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 409 Compounds of the general formula I.1 where R 2 is methyl and R 4 is trans-2-bromobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 410 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is trans-2-bromobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 411 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is trans-2-bromobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 412 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is trans-2-bromobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 413 Compounds of the general formula I.1 where R 2 is methyl and R 4 is cis-2-bromobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 414 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is cis-2-bromobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0 1 N 0050/46043 Table 415 Compounds of the general formula 1.3 where R 2 is cis-2-bromobut-2-enyl and the substituent R 3 for corresponds to in each case one line of Table B.
Table 416 Compounds of the general formula 1.4 where R 2 is cis-2-bromobut-2-enyl and the substituent R 3 for corresponds to in each case one line of Table B.
Table 417 Compounds of the general formula I.1 where R 2 is cis-3-bromobut-2-enyl and the substituent R 3 for corresponds to in each case one line of Table B.
Table 418 Compounds of the general formula 1.2 where R 2 is cis-3-bromobut-2-enyl and the substituent R 3 for corresponds to in each case one line of Table B.
Table 419 Compounds of the general formula 1.3 where R 2 is cis-3-bromobut-2-enyl and the substituent R 3 for corresponds to in each case one line of Table B.
Table 420 Compounds of the general formula 1.4 where R 2 is cis-3-bromobut-2-enyl and the substituent R 3 for corresponds to in each case one line of Table B.
methyl and R 4 is a compound methyl and R 4 is a compound methyl and R 4 is a compound methyl and R 4 is a compound methyl and R 4 is a compound methyl and R 4 is a compound Table 421 Compounds of the general formula I.1 where R 2 is methyl and R 4 is trans-3-bromobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 422 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is trans-3-bromobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 423 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is trans-3-bromobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
r 0050/46043 77 Table 424 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is trans-3-bromobut-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 425 Compounds of the general formula I.1 where R 2 is methyl and R 4 is prop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 426 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is prop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 427 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is prop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 428 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is prop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 429 Compounds of the general formula I.1 where R 2 is 3-chloroprop-2-ynyl and the substituent R 3 for a corresponds to in each case one line of Table B.
Table 430 Compounds of the general formula 1.2 where R 2 is 3-chloroprop-2-ynyl and the substituent R 3 for a corresponds to in each case one line of Table B.
Table 431 Compounds of the general formula 1.3 where R 2 is 3-chloroprop-2-ynyl and the substituent R 3 for a corresponds to in each case one line of Table B.
Table 432 Compounds of the general formula 1.4 where R 2 is 3-chloroprop-2-ynyl and the substituent R 3 for a corresponds to in each case one line of Table B.
methyl and R 4 is compound methyl and R 4 is compound methyl and R 4 is compound methyl and R 4 is compound 0050/46043 Table 433 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 3-bromoprop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 434 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 3-bromoprop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 435 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 3-bromoprop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 436 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 3-bromoprop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 437 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 3-iodoprop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 438 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 3-iodoprop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 439 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 3-iodoprop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 440 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 3-iodoprop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 441 Compounds of the general formula I.1 where R 2 is methyl and R 4 is but-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 79 Table 442 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is but-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 443 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is but-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 444 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is but-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 445 Compounds of the general formula I.1 where R 2 is but-3-ynyl and the substituent R 3 for a compound each case one line of Table B.
Table 446 Compounds of the general formula 1.2 where R 2 is but-3-ynyl and the substituent R 3 for a compound each case one line of Table B.
Table 447 Compounds of the general formula 1.3 where R 2 is but-3-ynyl and the substituent R 3 for a compound each case one line of Table B.
Table 448 Compounds of the general formula 1.4 where R 2 is but-3-ynyl and the substituent R 3 for a compound each case one line of Table B.
methyl and R 4 is corresponds to in methyl and R 4 is corresponds to in methyl and R 4 is corresponds to in methyl and R 4 is corresponds to in Table 449 Compounds of the general formula I.1 where R 2 is methyl and R 4 is but-3-yn-2-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 450 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is but-3-yn-2-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 Table 451 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is but-3-yn-2-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 452 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is but-3-yn-2-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 453 Compounds of the general formula I.1 where R 2 is methyl and R 4 is pent-4-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 454 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is pent-4-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 455 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is pent-4-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 456 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is pent-4-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 457 Compounds of the general formula I.1 where R 2 is methyl and R 4 is pent-3-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 458 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is pent-3-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 459 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is pent-3-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 81 Table 460 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is pent-3-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 461 Compounds of the general formula I.1 where R 2 is methyl and R 4 is pent-3-yn-2-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 462 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is pent-3-yn-2-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 463 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is pent-3-yn-2-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 464 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is pent-3-yn-2-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 465 Compounds of the general formula I.1 where R 2 is methyl and R 4 is pent-4-yn-2-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 466 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is pent-4-yn-2-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 467 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is pent-4-yn-2-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 468 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is pent-4-yn-2-yl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
/A4,\ 0050/46043 Table 469 Compounds of the general formula I.1 where 2 -vinyloxyethyl and the substituent R 3 for to in each case one line of Table B.
Table 470 Compounds of the general formula 1.2 where 2-vinyloxyethyl and the substituent R 3 for to in each case one line of Table B.
R
2 is methyl and R 4 is a compound corresponds
R
2 is methyl and R 4 is a compound corresponds Table 471 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 2-vinyloxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 472 Compounds of the general formula 1.4 where 2-vinyloxyethyl and the substituent R 3 for to in each case one line of Table B.
Table 473 Compounds of the general formula I.1 where 2-allyloxyethyl and the substituent R 3 for to in each case one line of Table B.
R
2 is methyl and R 4 is a compound corresponds
R
2 is methyl and R 4 is a compound corresponds Table 474 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 2-allyloxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 475 Compounds of the general formula 1.3 where 2-allyloxyethyl and the substituent R 3 for to in each case one line of Table B.
Table 476 Compounds of the general formula 1.4 where 2-allyloxyethyl and the substituent R 3 for to in each case one line of Table B.
R
2 is methyl and R 4 is a compound corresponds
R
2 is methyl and R 4 is a compound corresponds Table 477 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 2-trifluoromethoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 83 Table 478 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 2-trifluoromethoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 479 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 2-trifluoromethoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 480 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 2-trifluoromethoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 481 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 3-trifluoromethoxypropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 482 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 3-trifluoromethoxypropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 483 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 3-trifluoromethoxypropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 484 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 3-trifluoromethoxypropyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 485 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 4-trifluoromethoxybutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 486 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 4 -trifluoromethoxybutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 84 Table 487 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 4-trifluoromethoxybutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 488 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 4-trifluoromethoxybutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 489 Compounds of the general formula I.1 where R 2 is hydroxycarbonylmethyl and the substituent R 3 for corresponds to in each case one line of Table B.
Table 490 Compounds of the general formula 1.2 where R 2 is hydroxycarbonylmethyl and the substituent R 3 for corresponds to in each case one line of Table B.
Table 491 Compounds of the general formula 1.3 where R 2 is hydroxycarbonylmethyl and the substituent R 3 for corresponds to in each case one line of Table B.
Table 492 Compounds of the general formula 1.4 where R 2 is hydroxycarbonylmethyl and the substituent R 3 for corresponds to in each case one line of Table B.
Table 493 Compounds of the general formula I.1 where R 2 is methoxycarbonylmethyl and the substituent R 3 for corresponds to in each case one line of Table B.
Table 494 Compounds of the general formula 1.2 where R 2 is methoxycarbonylmethyl and the substituent R 3 for corresponds to in each case one line of Table B.
Table 495 Compounds of the general formula 1.3 where R 2 is methoxycarbonylmethyl and the substituent R 3 for corresponds to in each case one line of Table B.
methyl and R 4 is a compound methyl and R 4 is a compound methyl and R 4 is a compound methyl and R 4 is a compound methyl and R 4 is a compound methyl and R 4 is a compound methyl and R 4 is a compound 0050/46043 Table 496 Compounds of the general formula 1.4 where R 2 is methoxycarbonylmethyl and the substituent R 3 for corresponds to in each case one line of Table B.
Table 497 Compounds of the general formula I.1 where R 2 is aminocarbonylmethyl and the substituent R 3 for a corresponds to in each case one line of Table B.
Table 498 Compounds of the general formula 1.2 where R 2 is aminocarbonylmethyl and the substituent R 3 for a corresponds to in each case one line of Table B.
Table 499 Compounds of the general formula 1.3 where R 2 is aminocarbonylmethyl and the substituent R 3 for a corresponds to in each case one line of Table B.
Table 500 Compounds of the general formula 1.4 where R 2 is aminocarbonylmethyl and the substituent R 3 for a corresponds to in each case one line of Table B.
methyl and R 4 is a compound methyl and R 4 is compound methyl and R 4 is compound methyl and R 4 is compound methyl and R 4 is compound Table 501 Compounds of the general formula I.1 where R 2 is methyl and R 4 is N-methylaminocarbonylmethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 502 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is N-methylaminocarbonylmethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 503 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is N-methylaminocarbonylmethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 504 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is N-methylaminocarbonylmethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 86 Table 505 Compounds of the general formula I.1 where R 2 is methyl and R 4 is N,N-dimethylaminocarbonylmethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 506 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is N,N-dimethylaminocarbonylmethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 507 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is N,N-dimethylaminocarbonylmethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 508 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is N,N-dimethylaminocarbonylmethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 509 Compounds of the general formula I.1 where R 2 is 2-hydroxycarbonylethyl and the substituent R 3 fo: corresponds to in each case one line of Table B.
Table 510 Compounds of the general formula 1.2 where R 2 is 2-hydroxycarbonylethyl and the substituent R 3 fo: corresponds to in each case one line of Table B.
Table 511 Compounds of the general formula 1.3 where R 2 is 2-hydroxycarbonylethyl and the substituent R 3 foj corresponds to in each case one line of Table B.
Table 512 Compounds of the general formula 1.4 where R 2 is 2-hydroxycarbonylethyl and the substituent R 3 fo] corresponds to in each case one line of Table B.
methyl and R 4 is r a compound methyl and R 4 is r a compound methyl and R 4 is r a compound methyl and R 4 is r a compound methyl and R 4 is r a compound Table 513 Compounds of the general formula I.1 where R 2 2-methoxycarbonylethyl and the substituent R 3 corresponds to in each case one line of Table is foi
B.
0050/46043 Table 514 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 2 -methoxycarbonylethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 515 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 2-methoxycarbonylethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 516 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 2-methoxycarbonylethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 517 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 2-aminocarbonylethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 518 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 2-aminocarbonylethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 519 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 2-aminocarbonylethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 520 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 2-aminocarbonylethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 521 Compounds of the general formula I.1 2-N-methylaminocarbonylethyl and the corresponds to in each case one line Table 522 Compounds of the general formula 1.2 2-N-methylaminocarbonylethyl and the corresponds to in each case one line where R 2 is methyl and R 4 is substituent R 3 for a compound of Table B.
where R 2 is methyl and R 4 is substituent R 3 for a compound of Table B.
0050/46043 Table 523 Compounds of the general formula 1.3 2-N-methylaminocarbonylethyl and the corresponds to in each case one line Table 524 Compounds of the general formula 1.4 2-N-methylaminocarbonylethyl and the corresponds to in each case one line Table 525 Compounds of the general formula I.1 2-N,N-dimethylaminocarbonylethyl and compound corresponds to in each case Table 526 Compounds of the general formula 1.2 2-N,N-dimethylaminocarbonylethyl and compound corresponds to in each case where R 2 is methyl and R 4 is substituent R 3 for a compound of Table B.
where R 2 is methyl and R 4 is substituent R 3 for a compound of Table B.
where R 2 is methyl and the substituent R 3 for one line of Table B.
where R 2 is methyl and the substituent R 3 for one line of Table B.
R
4 is a
R
4 is a Table 527 Compounds of the general formula 1.3 2-N,N-dimethylaminocarbonylethyl and compound corresponds to in each case Table 528 Compounds of the general formula 1.4 2-N,N-dimethylaminocarbonylethyl and compound corresponds to in each case where R 2 is methyl and R 4 is the substituent R 3 for a one line of Table B.
where R 2 is methyl and the substituent R 3 for one line of Table B.
R
4 is a Table 529 Compounds of 2-aminoethyl in each case Table 530 Compounds of 2-aminoethyl in each case Table 531 Compounds of 2-aminoethyl in each case the general formula I.1 where R 2 is methyl and R 4 is and one the and one the and one the substituent R 3 for a compound corresponds to line of Table B.
general formula 1.2 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
general formula 1.3 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
0050/46043 89 Table 532 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 2-aminoethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 533 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 2-N-methylaminoethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 534 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 2-N-methylaminoethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 535 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 2-N-methylaminoethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 536 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 2-N-methylaminoethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 537 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 2-N,N-dimethylaminoethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 538 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 2-N,N-dimethylaminoethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 539 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 2-N,N-dimethylaminoethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 540 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 2-N,N-dimethylaminoethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
LI
^<3WZ N? 0050/46043 Table 541 Compounds of the general formula I.1 2-aminopropyl and the substituent R 3 in each case one line of Table B.
Table 542 Compounds of the general formula 1.2 2-aminopropyl and the substituent R 3 in each case one line of Table B.
Table 543 Compounds of the general formula 1.3 2-aminopropyl and the substituent R 3 in each case one line of Table B.
Table 544 Compounds of the general formula 1.4 2-aminopropyl and the substituent R 3 in each case one line of Table B.
where R 2 is methyl and R 4 is for a compound corresponds to where for a
R
2 is methyl and R 4 is compound corresponds to where R 2 is methyl and R 4 is for a compound corresponds to where R 2 is methyl and R 4 is for a compound corresponds to Table 545 Compounds of the general formula I.1 where R 2 is 2-N-methylaminopropyl and the substituent R 3 for corresponds to in each case one line of Table B.
Table 546 Compounds of the general formula 1.2 where R 2 is 2-N-methylaminopropyl and the substituent R 3 for corresponds to in each case one line of Table B.
Table 547 Compounds of the general formula 1.3 where R 2 is 2-N-methylaminopropyl and the substituent R 3 for corresponds to in each case one line of Table B.
Table 548 Compounds of the general formula 1.4 where R 2 is 2-N-methylaminopropyl and the substituent R 3 for corresponds to in each case one line of Table B.
Table 549 Compounds of the general formula I.1 where R 2 is 2-N,N-dimethylaminopropyl and the substituent R 3 corresponds to in each case one line of Table B.
methyl and R 4 is a compound methyl and R 4 is a compound methyl and R 4 is a compound methyl and R 4 is a compound methyl and R 4 is for a compound m C~: K 0050/46043 Table 550 Compounds of the general formula 1.2 where R 2 2-N,N-dimethylaminopropyl and the substituent corresponds to in each case one line of Table is
R
3
B.
Table 551 Compounds of the general formula 1.3 where R 2 is 2-N,N-dimethylaminopropyl and the substituent R 3 corresponds to in each case one line of Table B.
Table 552 Compounds of the general formula 1.4 where R 2 is 2-N,N-dimethylaminopropyl and the substituent R 3 corresponds to in each case one line of Table B.
methyl and R 4 is for a compound methyl and R 4 is for a compound methyl and R 4 is for a compound Table 553 Compounds of the general formula I.1 3-aminopropyl and the substituent R 3 in each case one line of Table B.
Table 554 Compounds of the general formula 1.2 3-aminopropyl and the substituent R 3 in each case one line of Table B.
Table 555 Compounds of the general formula 1.3 3-aminopropyl and the substituent R 3 in each case one line of Table B.
Table 556 Compounds of the general formula 1.4 3-aminopropyl and the substituent R 3 in each case one line of Table B.
Table 557 Compounds of the general formula I.1 where for a
R
2 is methyl and R 4 is compound corresponds to where R 2 is methyl and R 4 is for a compound corresponds to where R 2 is methyl and R 4 is for a compound corresponds to where R 2 is methyl and R 4 is for a compound corresponds to where R 2 is methyl and R 4 is 3-N-methylaminopropyl and the substituent R 3 for corresponds to in each case one line of Table B.
Table 558 Compounds of the general formula 1.2 where R 2 is 3-N-methylaminopropyl and the substituent R 3 for corresponds to in each case one line of Table B.
a compound methyl and R 4 is a compound 0050/46043 Table 559 Compounds of the general formula 1.3 where R 2 is 3-N-methylaminopropyl and the substituent R 3 for corresponds to in each case one line of Table B.
Table 560 Compounds of the general formula I.4 where R 2 is 3-N-methylaminopropyl and the substituent R 3 for corresponds to in each case one line of Table B.
Table 561 Compounds of the general formula I.1 where R 2 is 3-N,N-dimethylaminopropyl and the substituent R 3 corresponds to in each case one line of Table B.
Table 562 Compounds of the general formula 1.2 where R 2 is 3-N,N-dimethylaminopropyl and the substituent R 3 corresponds to in each case one line of Table B.
Table 563 Compounds of the general formula 1.3 where R 2 is 3-N,N-dimethylaminopropyl and the substituent R 3 corresponds to in each case one line of Table B.
Table 564 Compounds of the general formula I.4 where R 2 is 3-N,N-dimethylaminopropyl and the substituent R 3 corresponds to in each case one line of Table B.
methyl and R 4 is a compound methyl and R 4 is a compound methyl and R 4 is for a compound methyl and R 4 is for a compound methyl and R 4 is for a compound methyl and R 4 is for a compound Table 565 Compounds of 4-aminobutyl in each case Table 566 Compounds of 4-aminobutyl in each case the and one the and one general formula I.1 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
general formula 1.2 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
general formula 1.3 where R 2 is methyl and R 4 is the substituent R 3 for a compound corresponds to line of Table B.
Table 567 Compounds of 4-aminobutyl in each case *%0 the and one 0050/46043 93 Table 568 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 4-aminobutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 569 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 4-N-methylaminobutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 570 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 4-N-methylaminobutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 571 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 4-N-methylaminobutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 572 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 4-N-methylaminobutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 573 Compounds of the general formula I.1 where R 2 is methyl and R 4 is 4-N,N-dimethylaminobutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 574 Compounds of the general formula 1.2 where R 2 is methyl and R 4 is 4-N,N-dimethylaminobutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 575 Compounds of the general formula 1.3 where R 2 is methyl and R 4 is 4-N,N-dimethylaminobutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 576 Compounds of the general formula 1.4 where R 2 is methyl and R 4 is 4-N,N-dimethylaminobutyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 94 Table 577 Compounds of the general formula I.1 where R 2 is hydrogen and R 4 is hydrogen and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 578 Compounds of the general formula 1.2 where R 2 is hydrogen and R 4 is hydrogen and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 579 Compounds of the general formula 1.3 where R 2 is hydrogen and R 4 is hydrogen and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 580 Compounds of the general formula 1.4 where R 2 is hydrogen and R 4 is hydrogen and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 581 Compounds is methyl each case Table 582 Compounds is methyl each case Table 583 Compounds is methyl each case Table 584 Compounds is methyl each case of the general formula and the substituent R 3 one line of Table B.
of the general formula and the substituent R 3 one line of Table B.
of the general formula and the substituent R 3 one line of Table B.
of the general formula and the substituent R 3 one line of Table B.
I.1 where R 2 is hydrogen and R 4 for a compound corresponds to in 1.2 where R 2 is hydrogen and R 4 for a compound corresponds to in 1.3 where R 2 is hydrogen and R 4 for a compound corresponds to in 1.4 where R 2 is hydrogen and R 4 for a compound corresponds to in Table 585 Compounds of the general formula I.1 where R 2 is hydrogen and R 4 is ethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
I M M I 0050/46043 Table 586 Compounds of the general formula 1.2 where R 2 is hydrogen and R 4 is ethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 587 Compounds of the general formula 1.3 where R 2 is hydrogen and R 4 is ethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 588 Compounds of the general formula 1.4 where R 2 is hydrogen and R 4 is ethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 589 Compounds of the general formula I.1 where R 2 is hydrogen and R 4 is n-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 590 Compounds of the general formula 1.2 where R 2 is hydrogen and R 4 is n-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 591 Compounds of the general formula 1.3 where R 2 is hydrogen and R 4 is n-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 592 Compounds of the general formula I.4 where R 2 is hydrogen and R 4 is n-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 593 Compounds of the general formula I.1 where R 2 is hydrogen and R 4 is iso-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 594 Compounds of the general formula 1.2 where R 2 is hydrogen and R 4 is iso-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 96 Table 595 Compounds of the general formula 1.3 where R 2 is hydrogen and R 4 is iso-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 596 Compounds of the general formula 1.4 where R 2 is hydrogen and R 4 is iso-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 597 Compounds of the general formula I.1 where R 2 is hydrogen and R 4 is 2-methoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 598 Compounds of the general formula 1.2 where R 2 is hydrogen and R 4 is 2-methoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 599 Compounds of the general formula 1.3 where R 2 is hydrogen and R 4 is 2-methoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 600 Compounds of the general formula 1.4 where R 2 is hydrogen and R 4 is 2-methoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 601 Compounds of the general formula I.1 where R 2 is hydrogen and R 4 is prop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 602 Compounds of the general formula 1.2 where R 2 is hydrogen and R 4 is prop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 603 Compounds of the general formula 1.3 where R 2 is hydrogen and R 4 is prop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 97 Table 604 Compounds of the general formula 1.4 where R 2 is hydrogen and R 4 is prop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 605 Compounds of the general formula I.1 is trans-3-chloroprop-2-enyl and the corresponds to in each case one line Table 606 Compounds of the general formula 1.2 is trans-3-chloroprop-2-enyl and the corresponds to in each case one line Table 607 Compounds of the general formula 1.3 is trans-3-chloroprop-2-enyl and the corresponds to in each case one line Table 608 Compounds of the general formula 1.4 is trans-3-chloroprop-2-enyl and the corresponds to in each case one line where R 2 is substituent of Table B.
where R 2 is substituent of Table B.
where R 2 is substituent of Table B.
where R 2 is substituent of Table B.
hydrogen and R 4
R
3 for a compound hydrogen and R 4
R
3 for a compound hydrogen and R 4
R
3 for a compound hydrogen and R 4
R
3 for a compound Table 609 Compounds of the general formula I.1 where R 2 is hydrogen and R 4 is prop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 610 Compounds of the general formula 1.2 where R 2 is hydrogen and R 4 is prop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 611 Compounds of the general formula 1.3 where R 2 is hydrogen and R 4 is prop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 612 Compounds of the general formula 1.4 where R 2 is hydrogen and R 4 is prop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 98 Table 613 Compounds of the general formula I.1 where R 2 is hydrogen and R 4 is 3-iodoprop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 614 Compounds of the general formula 1.2 where R 2 is hydrogen and R 4 is 3-iodoprop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 615 Compounds of the general formula 1.3 where R 2 is hydrogen and R 4 is 3-iodoprop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 616 Compounds of the general formula 1.4 where R 2 is hydrogen and R 4 is 3-iodoprop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 617 Compounds of the general formula I.1 where R 2 is ethyl and R 4 is hydrogen and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 618 Compounds of the general formula 1.2 where R 2 is ethyl and R 4 is hydrogen and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 619 Compounds of the general formula 1.3 where R 2 is ethyl and R 4 is hydrogen and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 620 Compounds of the general formula 1.4 where R 2 is ethyl and R 4 is hydrogen and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 621 Compounds of the general formula I.1 where R 2 is ethyl and R 4 is methyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 99 Table 622 Compounds of the general formula 1.2 where R 2 is ethyl and R 4 is methyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 623 Compounds of the general formula 1.3 where R 2 is ethyl and R 4 is methyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 624 Compounds of the general formula 1.4 where R 2 is ethyl and R 4 is methyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 625 Compounds of the general formula I.1 where R 2 is ethyl and R 4 is ethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 626 Compounds of the general formula 1.2 where R 2 is ethyl and R 4 is ethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 627 Compounds of the general formula 1.3 where R 2 is ethyl and R 4 is ethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 628 Compounds of the general formula 1.4 where R 2 is ethyl and R 4 is ethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 629 Compound [sic] of the general formula I.1 where R 2 is ethyl and R 4 is n-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 630 Compound [sic] of the general formula 1.2 where R 2 is ethyl and R 4 is n-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 100 Table 631 Compound [sic] of the general formula 1.3 where R 2 is ethyl and R 4 is n-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 632 Compound [sic] of the general formula 1.4 where R 2 is ethyl and R 4 is n-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 633 Compound [sic] of the is iso-propyl and the in each case one line Table 634 Compound [sic] of the is iso-propyl and the in each case one line Table 635 Compound [sic] of the is iso-propyl and the in each case one line Table 636 Compound [sic] of the is iso-propyl and the in each case one line general formula I.1 where R 2 is ethyl and R 4 substituent R 3 for a compound corresponds to of Table B.
general formula 1.2 where R 2 is ethyl and R 4 substituent R 3 for a compound corresponds to of Table B.
general formula 1.3 where R 2 is ethyl and R 4 substituent R 3 for a compound corresponds to of Table B.
general formula 1.4 where R 2 is ethyl and R 4 substituent R 3 for a compound corresponds to of Table B.
general formula I.1 where R 2 is ethyl and R 4 the substituent R 3 for a compound Table 637 Compound [sic] of is 2-methoxyethyl the and corresponds to in each case one line of Table B.
Table 638 Compound [sic] of is 2-methoxyethyl corresponds to in Table 639 Compound [sic] of is 2-methoxyethyl corresponds to in the general formula 1.2 where R 2 is ethyl and R 4 and the substituent R 3 for a compound each case one line of Table B.
the general formula 1.3 where R 2 is ethyl and R 4 and the substituent R 3 for a compound each case one line of Table B.
0050/46043 101 Table 640 Compound [sic] of the general formula 1.4 where R 2 is ethyl and R 4 is 2-methoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 641 Compound [sic] of the general formula is prop-2-enyl and the substituent R 3 to in each case one line of Table B.
Table 642 Compound [sic] of the general formula is prop-2-enyl and the substituent R 3 to in each case one line of Table B.
Table 643 Compound [sic] of the general formula is prop-2-enyl and the substituent R 3 to in each case one line of Table B.
Table 644 Compound [sic] of the general formula is prop-2-enyl and the substituent R 3 to in each case one line of Table B.
1.1 where R 2 is ethyl and R 4 for a compound corresponds 1.2 where R 2 is ethyl and R 4 for a compound corresponds 1.3 for where R 2 is ethyl and R 4 a compound corresponds 1.4 where R 2 is ethyl and R 4 for a compound corresponds Table 645 Compound [sic] of the general formula I.1 where R 2 is ethyl and R 4 is trans-3-chloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 646 Compound [sic] of the general formula 1.2 where R 2 is ethyl and R 4 is trans-3-chloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 647 Compound [sic] of the general formula 1.3 where R 2 is ethyl and R 4 is trans-3-chloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 648 Compound [sic] of the general formula 1.4 where R 2 is ethyl and R 4 is trans-3-chloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 102 Table 649 Compound [sic] of the general formula is prop-2-ynyl and the substituent R 3 to in each case one line of Table B.
Table 650 Compound [sic] of the general formula is prop-2-ynyl and the substituent R 3 to in each case one line of Table B.
Table 651 Compound [sic] of the general formula is prop-2-ynyl and the substituent R 3 to in each case one line of Table B.
Table 652 Compound [sic] of the general formula is prop-2-ynyl and the substituent R 3 to in each case one line of Table B.
I.1 where R 2 is ethyl and R 4 for a compound corresponds 1.2 for where R 2 is ethyl and R 4 a compound corresponds 1.3 where R 2 is ethyl and R 4 for a compound corresponds 1.4 where R 2 is ethyl and R 4 for a compound corresponds Table 653 Compound [sic] of the general formula I.1 where R 2 is ethyl and R 4 is 3-iodoprop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 654 Compound [sic] of the general formula 1.2 where R 2 is ethyl and R 4 is 3-iodoprop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 655 Compound [sic] of the general formula 1.3 where R 2 is ethyl and R 4 is 3-iodoprop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 656 Compound [sic] of the general formula 1.4 where R 2 is ethyl and R 4 is 3-iodoprop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 657 Compound [sic] of the general formula I.1 where R 2 is trifluoromethyl and R 4 is hydrogen and the substituent R 3 for a compound corresponds to in each case one line of Table B.
TG ~d
U*
0050/46043 103 Table 658 Compound [sic] of the general formula 1.2 where R 2 is trifluoromethyl and R 4 is hydrogen and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 659 Compound [sic] of the general formula 1.3 where R 2 is trifluoromethyl and R 4 is hydrogen and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 660 Compound [sic] of the general formula 1.4 where R 2 is trifluoromethyl and R 4 is hydrogen and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 661 Compound [sic] of the general formula I.1 where R 2 is trifluoromethyl and R 4 is methyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 662 Compound [sic] of the general formula 1.2 where R 2 is trifluoromethyl and R 4 is methyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 663 Compound [sic] of the general formula 1.3 where R 2 is trifluoromethyl and R 4 is methyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 664 Compound [sic] of the general formula 1.4 where R 2 is trifluoromethyl and R 4 is methyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 665 Compound [sic] of the general formula I.1 where R 2 is trifluoromethyl and R 4 is ethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 666 Compound [sic] of the general formula 1.2 where R 2 is trifluoromethyl and R 4 is ethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 104 Table 667 Compound [sic] of the general formula 1.3 where R 2 is trifluoromethyl and R 4 is ethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 668 Compound [sic] of the general formula 1.4 where R 2 is trifluoromethyl and R 4 is ethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 669 Compound [sic] of the general formula I.1 where R 2 is trifluoromethyl and R 4 is n-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 670 Compound [sic] of the general formula 1.2 where R 2 is trifluoromethyl and R 4 is n-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 671 Compound [sic] of the general formula 1.3 where R 2 is trifluoromethyl and R 4 is n-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 672 Compound [sic] of the general formula 1.4 where R 2 is trifluoromethyl and R 4 is n-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 673 Compound [sic] of the general formula I.1 where R 2 is trifluoromethyl and R 4 is iso-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 674 Compound [sic] of the general formula 1.2 where R 2 is trifluoromethyl and R 4 is iso-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 675 Compound [sic] of the general formula 1.3 where R 2 is trifluoromethyl and R 4 is iso-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
,V
A
0050/46043 105 Table 676 Compound [sic] of the general formula 1.4 where R 2 is trifluoromethyl and R 4 is iso-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 677 Compound [sic] of the general formula I.1 where R 2 is trifluoromethyl and R 4 is 2-methoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 678 Compound [sic] of the general formula 1.2 where R 2 is trifluoromethyl and R 4 is 2-methoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 679 Compound [sic] of the general formula 1.3 where R 2 is trifluoromethyl and R 4 is 2-methoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 680 Compound [sic] of the general formula 1.4 where R 2 is trifluoromethyl and R 4 is 2-methoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 681 Compound [sic] of the general formula I.1 where R 2 is trifluoromethyl and R 4 is prop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 682 Compound [sic] of the general formula 1.2 where R 2 is trifluoromethyl and R 4 is prop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 683 Compound [sic] of the general formula 1.3 where R 2 is trifluoromethyl and R 4 is prop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 684 Compound [sic] of the general formula 1.4 where R 2 is trifluoromethyl and R 4 is prop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0 n S'\.i 0050/46043 106 Table 685 Compound [sic] of the general formula I.1 where R 2 is trifluoromethyl and R 4 is trans-3-chloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 686 Compound [sic] of the general formula 1.2 where R 2 is trifluoromethyl and R 4 is trans-3-chloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 687 Compound [sic] of the general formula 1.3 where R 2 is trifluoromethyl and R 4 is trans-3-chloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 688 Compound [sic] of the general formula 1.4 where R 2 is trifluoromethyl and R 4 is trans-3-chloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 689 Compound [sic] of the general formula I.1 where R 2 is trifluoromethyl and R 4 is prop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 690 Compound [sic] of the general formula 1.2 where R 2 is trifluoromethyl and R 4 is prop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 691 Compound [sic] of the general formula 1.3 where R 2 is trifluoromethyl and R 4 is prop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 692 Compound [sic] of the general formula 1.4 where R 2 is trifluoromethyl and R 4 is prop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 107 Table 693 Compound [sic] of the general formula I.1 where R 2 is trifluoromethyl and R 4 is 3-iodoprop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 694 Compound [sic] of the general formula 1.2 where R 2 is trifluoromethyl and R 4 is 3-iodoprop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 695 Compound [sic] of the general formula 1.3 where R 2 is trifluoromethyl and R 4 is 3-iodoprop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 696 Compound [sic] of the general formula 1.4 where R 2 is trifluoromethyl and R 4 is 3-iodoprop-2-ynyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 697 Compound [sic] of the general formula I.1 where R 2 is cyclopropyl and R 4 is hydrogen and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 698 Compound [sic] of the general formula 1.2 where R 2 is cyclopropyl and R 4 is hydrogen and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 699 Compound [sic] of the general formula 1.3 where R 2 is cyclopropyl and R 4 is hydrogen and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 700 Compound [sic] of the general formula 1.4 where R 2 is cyclopropyl and R 4 is hydrogen and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 701 Compound [sic] of the general formula I.1 where R 2 is cyclopropyl and R 4 is methyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 108 Table 702 Compound [sic] of the general formula 1.2 where R 2 is cyclopropyl and R 4 is methyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 703 Compound [sic] of the general formula 1.3 where R 2 is cyclopropyl and R 4 is methyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 704 Compound [sic] of the general formula 1.4 where R 2 is cyclopropyl and R 4 is methyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 705 Compound [sic] of the general formula I.1 where R 2 is and R 4 is ethyl and the substituent R 3 for a compound to in each case one line of Table B.
Table 706 Compound [sic] of the general formula 1.2 where R 2 is and R 4 is ethyl and the substituent R 3 for a compound to in each case one line of Table B.
cyclopropyl corresponds cyclopropyl corresponds Table 707 Compound [sic] of the general formula 1.3 where R 2 is cyclopropyl and R 4 is ethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 708 Compound [sic] of the general formula 1.4 where R 2 is cyclopropyl and R 4 is ethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 709 Compound [sic] of the general formula I.1 where R 2 is cyclopropyl and R 4 is n-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 710 Compound [sic] of the general formula 1.2 where R 2 is cyclopropyl and R 4 is n-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 109 Table 711 Compound [sic] of the general formula 1.3 where R 2 is cyclopropyl and R 4 is n-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 712 Compound [sic] of the general formula 1.4 where R 2 is cyclopropyl and R 4 is n-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 713 Compound [sic] of the general formula I.1 where R 2 is cyclopropyl and R 4 is iso-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 714 Compound [sic] of the general formula 1.2 where R 2 is cyclopropyl and R 4 is iso-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 715 Compound [sic] of the general formula 1.3 where R 2 is cyclopropyl and R 4 is iso-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 716 Compound [sic] of the general formula 1.4 where R 2 is cyclopropyl and R 4 is iso-propyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 717 Compound [sic] of the general formula I.1 where R 2 is cyclopropyl and R 4 is 2-methoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 718 Compound [sic] of the general formula 1.2 where R 2 is cyclopropyl and R 4 is 2-methoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 719 Compound [sic] of the general formula 1.3 where R 2 is cyclopropyl and R 4 is 2-methoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
0050/46043 110 Table 720 Compound [sic] of the general formula 1.4 where R 2 is cyclopropyl and R 4 is 2-methoxyethyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 721 Compound [sic] of the general formula I.1 where R 2 and R 4 is prop-2-enyl and the substituent R 3 for a corresponds to in each case one line of Table B.
Table 722 Compound [sic] of the general formula 1.2 where R 2 and R 4 is prop-2-enyl and the substituent R 3 for a corresponds to in each case one line of Table B.
Table 723 Compound [sic] of the general formula 1.3 where R 2 and R 4 is prop-2-enyl and the substituent R 3 for a corresponds to in each case one line of Table B.
Table 724 Compound [sic] of the general formula 1.4 where R 2 and R 4 is prop-2-enyl and the substituent R 3 for a corresponds to in each case one line of Table B.
is cyclopropyl compound is cyclopropyl compound is cyclopropyl compound is cyclopropyl compound Table 725 Compound [sic] of the general formula I.1 where R 2 is cyclopropyl and R 4 is trans-3-chloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 726 Compound [sic] of the general formula 1.2 where R 2 is cyclopropyl and R 4 is trans-3-chloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 727 Compound [sic] of the general formula 1.3 where R 2 is cyclopropyl and R 4 is trans-3-chloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
Table 728 Compound [sic] of the general formula 1.4 where R 2 is cyclopropyl and R 4 is trans-3-chloroprop-2-enyl and the substituent R 3 for a compound corresponds to in each case one line of Table B.
V7 4 0050/46043 111 Table 729 Compound [sic] of the general formula I.1 where R 2 and R 4 is prop-2-ynyl and the substituent R 3 for a corresponds to in each case one line of Table B.
Table 730 Compound [sic] of the general formula 1.2 where R 2 and R 4 is prop-2-ynyl and the substituent R 3 for a corresponds to in each case one line of Table B.
Table 731 Compound [sic] of the general formula 1.3 where R 2 and R 4 is prop-2-ynyl and the substituent R 3 for a corresponds to in each case one line of Table B.
Table 732 Compound [sic] of the general formula 1.4 where R 2 and R 4 is prop-2-ynyl and the substituent R 3 for a corresponds to in each case one line of Table B.
Table 733 Compound [sic] of the general formula I.1 where R 2 and R 4 is 3-iodoprop-2-ynyl and the substituent R 3 corresponds to in each case one line of Table B.
Table 734 Compound [sic] of the general formula 1.2 where R 2 and R 4 is 3-iodoprop-2-ynyl and the substituent R 3 corresponds to in each case one line of Table B.
Table 735 Compound [sic] of the general formula 1.3 where R 2 and R 4 is 3-iodoprop-2-ynyl and the substituent R 3 corresponds to in each case one line of Table B.
Table 736 Compound [sic] of the general formula 1.4 where R 2 and R 4 is 3-iodoprop-2-ynyl and the substituent R 3 corresponds to in each case one line of Table B.
is cyclopropyl compound is cyclopropyl compound is cyclopropyl compound is cyclopropyl compound is cyclopropyl for a compound is cyclopropyl for a compound is cyclopropyl for a compound is cyclopropyl for a compound 0050/46043 112 Table A No.R24 A. 1 OH 3
H
A. 2 OH 3 OH 3 A. 3 CH 3 C 2
H
A. 4 OH 3 n-C 3
H
7 A. 5 CH 3 i-C 3
H
7 A.6 IOH 3 cyclopropyl A.7 OH 3 n-C 4
H
9 A.8 OH 3
S-C
4
H
9 A.9 CH 3 i-C 4
H
9 A. 10 CH 3 t-C 4 H9 A.11 CH 3 n-C 5 Hjj A.12 OH 3 i-C 5 Hjj A.13 OCH 3 neo-C 5
H
1 1 A.14 OH 3 cyclopentyl
OH
3 n-C 6
H
1 3 A.16 CH 3 cyclohexyl A.17 OH 3 n-C 8
H
17 A.18 OH 3 CH 2
CH
2 Cl A.19 OH 3 (CH 2 4 Cl
CH
3
CH
2
CN'
A.21 CH 3
CH
2
CH
2
CN
A.22 OH 3
(CH
2 3
CN
A.23 CH 3
(CH
2 4
CN
A.24 OH 3
(CH
2 6
CN
OH
3 cyclohexylmethyl A.26 OH 3 2-cyclohexyleth-1-yl A.27 OH 3 cyclopropylmethyl A.28 OH 3 2-cyclopropyleth-1-yl A.29 OH 3 2-methoxyeth-1-yl
OH
3 2-ethoxyeth-1-yl A.31 OH 3 2-isopropoxyeth-1-yl A.32 OCH 3 3-methoxyprop-1-yl A.33 OH 3 3-ethoxyprop-1-yl A.34 OH 3 3-isopropoxyprop-l-yl
CH
3 4-methoxybut-1-yl A.36 OH 3 4-isopropoxybut-1-yl A.37 OH 3 propen-3-yl A.38 OH 3 but-2-en-1-yl
Q
0.
0050/46043 113 No.R24 A.39 OH 3 3-methylbut-2-en-1-yl
OH
3 2-vinyloxyeth-1-yl A.41 OH 3 allyloxyeth-1-yl A. 42 OH 3 2-trifluoromethoxyeth-1-yl A. 43 CH 3 3-trifluoromethoxyprop-1-yl A. 44 OH 3 4-difluoromethoxybut-1-yl
CH
3 hydroxycarbonylmethyl A.46 CH 3 methoxycarbonylmethyl A.47 OH 3 aminocarbonylmethyl A. 48 CH 3 N-methylaminocarbonylmethyl A. 49 CH 3 N,N-dimethylaminocarbonyl-methyl A. 50 OH 3 2-hydroxycarbonyleth-1-yl A. 51 OH 3 2-methoxycarbonyleth-1-yl A.52 OH 3 2-aminocarbonyleth-i-yl A. 53 OH 3 2-n-Methylaminocarbonyleth-1-yl A. 54 OH 3 2-dimethylaminocarbonyleth-1-yl
CH
3 2-axninoeth-1-yl A.56 OH 3 2-aminoprop-1-yl A.57 OH 3 4-aminobut-1-yl A.58 OH 3 3-dimethylaminoprop-1-yl A. 59 CH 3 4-aminothiocarbonylbut-1-yl
OH
3 2-oxopropyl A.61 CH 3 cyclohexyl A.62 CH 3 cyclopropyl A.63 OH 3 cyclopentyl A.64 OH 3 2-methoxyiminoprop-1-yl
CH
3 2-methoxyiminoeth-1-yl A.66 CH 3 6-aiinocarbonylhex-1-yl A. 67 OH 3 3-aminothiocarbonylprop-1-yl A. 68 CH 3 2-aminothiocarbonyleth-1-yl A.69 CH 3 aminothiocarbonylmethyl
CH
3 4-(N,N-dimethylamino)but-1-yl A.71 OH 3 2-(methylthio)eth-1-yl A.72 OH 3 2-(methylsulfonyl)eth-1-yl A.73 OH 3 4-(methylthio)prop-1-yl A. 74 CH 3 4-(methylsulfonyl)prop-1-yl
OH
3 benyzi A. 76 OH 3 2-F-C 6
H
4
-CH
2 A.77 OH 3 3-F- 6
H
4
-CH
2
LI
0 0050/46043 114 No. R 2
R
A.78 CH 3 4-F-C 6
H
4
-CH
2 A.79 OH 3 2,3-F 2
-C
6
H
3
-CH
2
CH
3 2,4-F 2
-C
6
H
3 -0H 2 A.81 OH 3 2,5-F 2 6
H
3
-CH
2 A.82 OH 3 2,6-F 2 6
H
3
-CH
2 A.83 ICH 3 3,4-F 2 6
H
3
-CH
2 A.84 OH 3 3,5-F 2 6
H
3
-CH
2
OH
3 2-Cl-C 6
H
4
-CH
2 A.86 CH 3 3-Cl-C 6
H
4
-CH
2 A.87 CH 3 4-C1-C 6
H
4
-CH
2 A.88 OH 3 2,3-Cl 2 6
H
3
-CH
2 A.89 OH 3 2,4-C 2 6
H
3
-CH
2
OCH
3 2,5-C 2 6
H
3
-CH
2 A. 91 UH 3 2, 6-C 2 -CrH 3
-CH
2 A.92 OH 3 3,4-C1 2
-C
6
H
3
-CH
2 A.93 CH 3 3,5-C 2
-C
6
H
3
-CH
2 A.94 OH 3 2,3,4-1 3 6
H
2
-CH
2
OH
3 2,3,5-1 3
-C
6
H
2
-CH
2 A.96 OH 3 2,3,6-C 3
-C
6
H
2
-CH
2 A.97 OH 3 2,4,5-C 3
-C
6
H
2
-CH
2 A.98 OH 3 2,4,6-C1 3 6
H
2
-CH
2 A.99 OH 3 3,4,5-C1 3
-C
6
H
2
-CH
2 A. 100 CH 3 2-Br- 6
H
4
-CH
2 A.101 OH 3 3-Br-C 6
H
4
-CH
2 A.102 OH 3 4-Br-C 6
H
4
-CH
2 A.103 OH 3 2,3-Br 2 6
H
3
-CH
2 A.104 CH 3 2,4-Br 2
-C
6
H
3
-CH
2 A.105 CH 3 2,5-Br 2 6
H
3
-CH
2 A.106 CH 3 2,6-Br 2 6
H
3
-CH
2 A.107 CH 3 3,4-Br 2 6
H
3
-CH
2 A.108 OH 3 3,5-Br 2 6
H
3
-CH
2 A.109 CH 3 2-F, 3-C1-C 6
H
3
-CH
2 A.110 OH 3 2-F, 4-C1-C 6
H
3
-CH
2 A.111 OH 3 2-F, 5-C1-C 6
H
3
-CH
2 A.112 OH 3 2-F, 3-Br-C 6
H
3
-CH
2 A.113 OH 3 2-F, 4-Br-C 6
H
3
-CH
2 A.114 OH 3 2-F, 5-Br- 6
H
3
-CH
2 A.115 OH 3 2-01, 3-Br- 6
H
3
-OH
2 A.16 H 3 2-01, 4-Br- 6
H
3
-OH
2 0050/46043 115 No.R24 A.117 CH 3 2-Cl, 5-Br-C 6
H
3
-CH
2 A.118 CH 3 3-F, 4-Cl-C 6
H
3
-CH
2 A.119 CH 3 3-F, 5-Cl-C 6
H
3
-CH
2 A.120 CH 3 3-F, 6-Cl-C 6
H
3
-CH
2 A.121 CH 3 3-F, 4-Br-C 6
H
3
-CH
2 A.122 CH 3 3-F, 5-Br-C 6
H
3
-CH
2 A.123 CH 3 3-F, 6-Br-C 6
H
3
-CH
2 A.124 CH 3 3-Cl, 4-Br-C 6
H
3
-CH
2 A.125 CH 3 3-Cl, 5-Br-C 6
H
3
-CH
2 A.126 CH 3 3-Cl, 6-Br-C 6
H
3
-CH
2 A.127 CH 3 4-F, 5-Cl-C 6
H
3
-CH
2 A.128 CH 3 4-F, 6-Cl-C 6
H
3
-CH
2 A.129 CH 3 4-F, 5-Br-C 6
H
3
-CH
2 A. J30 CH 3 4-F, 6-Br-C 6
H
3
-CH
2 A.131 CH 3 4-Cl, 5-Br-C 6
H
3
-CH
2 A.132 CH 3 5-F, 6-Cl-C 6
H
3
-CH
2 A.133 CH 3 5-F, 6-Br-C 6
H
3
-CH
2 A.134 CH 3 5-Cl, 6-Br-C 6
H
3
-CH
2 A.135 CH 3 3-Br, 4-Cl, 5-Br-C 6
H
2
-CH
2 A.136 CH 3 2-CN-C 6
H
4
-CH
2 A. 137 CH 3 3-CN-C 6
H
4
-CH
2 A.138 CH 3 4-CN-C 6
H
4
-CH
2 A.139 CH 3 2-N0 2
-C
6
H
4
-CH
2 A.140 C1H, 3-N0 2
-C
6
H
4
-CH
2 A.141 CH 3 4-N0 2
-C
6
H
4
-CH
2 A.142 CH 3 2-CH 3
-C
6
H
4
-CH
2 A.143 CH 3 3-CH 3
-C
6
H
4
-CH
2 A.144 CH 3 4-CH 3
-C
6
H
4
-CH
2 A.145 CH 3 2,3-(CH 3 2
-C
6
H
3
-CH
2 A.46 C 3 ,4(H 3 2
P,
3
-H
A.146 CH, 2,5-(CH 3 2
-C
6
H
3
-CH
2 A.147 CH 3 2,6-(CH 3 2
-C
6
H
3
-CH
2 A.148 CH 3 3,4-(CH 3 2
-C
6
H
3
-CH
2 A.149 CH 3 3,5-(CH 3 2
-C
6
H
3
-CH
2 A.150 CH 3 2-C 2 5 -CH3)-C6H3-H A. 152 CH 3 3-C 2
H
5
-C
6
H
4
-CH
2 A.152 CH 3 4-C 2
H
5
-C
6
H
4
-CH
2 A.153 CH 3 2--CH-C 6
H
4
-CH
2 A.154 CH 3 3-i-C 3
H
7
-C
6
H
4 -CH 2 0050/46043 116 No.R24 A. 156 CH 3 4-i- 3
H
7
-C
6
H
4
-CH
2 A.157 CH 3 2-cyclohexyl- 6
H
4
-CH
2 A.158 CH 3 3-cyclohexyl-C 6
H
4
-CH
2 A.159 CH 3 4-cyclohexyl- 6
H
4
-CH
2 A.160 OH 3 2-vinyl-C 6
H
4
-CH
2 A.161 CH 3 3-vinyl- 6
H
4
-CH
2 A.162 OH 3 4-vinyl- 6
H
4
-CH
2 A. 163 OH 3 2-allYl-C 6
H
4
-CH
2 A.164 OH 3 3-allYl- 6
H
4
-CH
2 A.165 OH 3 4-allYl- 6
H
4
-CH
2 A. 166 CH 3 2-C 6
H
5
-C
6
H
4
-CH
2 A. 167 OH 3 3-C 6
H
5
-C
6
H
4
-CH
2 A.168 OH 3 4-C 6
H
5
-C
6
H
4
-CH
2 A.169 OH 3 3-OHM 3 5-t- 4
H
9 6
H
3
-CH
2 A.170 CH 3 2-OH-C 6
H
4
-CH
2 A.171 OH 3 3-OH-C 6
H
4
-CH
2 A.172 OH 3 4-OH-C 6
H
4
-CH
2 A.173 OH 3 2-00H 3
-C
6
H
4
-CH
2 A.174 OH 3 3-00H 3
-C
6
H
4
-CH
2 A.175 CH 3 4-00H 3
-C
6
H
4
-CH
2 A.176 CH 3 2,3-(0H 3 2 6
H
3
-CH
2 A.177 OH 3 2, 4- (0H 3 2 6
H
3
-CH
2 A.178 OH 3 2, 5- (0H 3 2
-C
6
H
3
-CH
2 A.179 CH 3 3,4-(00H 3 2
-C
6
H
3
-CH
2 A.180 OH 3 3,5-(00H 3 2
-C
6
H
3
-CH
2 A.181 CH 3 3,4,5-(00H 3 3
-C
6
H
2
-CH
2 A.182 OH 3 2-0C 2
H
5
-C
6
H
4
-CH
2 A. 183 OH 3 3-00 2
H
5
-C
6
H
4
-OH
2 A.184 CH 3 4-00 2
H
5
-C
6
H
4
-CH
2 A. 185 OH 3 2-0- (n-C 3
H
7 6
H
4
-CH
2 A. 186 OH 3 3-0- (n-C 3
H
7
-C
6
H
4
-CH
2 A. 187 OH 3 4-0- (n-O 3
H
7
-C
6
H
4
-OH
2 A. 188 OH 3 2-0- (i-0 3
H
7
-C
6 H4 -OH 2 A. 189 OH 3 3-0- i-0 3
H
7
-C
6
H
4
-OH
2 A. 190 OH 3 4-0- (i- 3
H
7 -0 6
H
4 -0H 2 A.191 OH 3 4-Q-(n- 4
H
9 6
H
4
-CH
2 A. 192 OH 3 3-0- (t-0 4
H
9 -0 6
H
4 -0H 2 A.193 OH 3 4-0- (n- 6 Hl 3 6
H
4
-CH
2 A. 194 OH 3 2-0-allYl- 6
H
4
-CH
2 0050/46043 117 No.R24 A. 195 CH 3 3-O-allYl-C 6 1 4
-CH
2 A. 196 CH 3 4-O-allYl- 6
H
4
-CH
2 A.197 OH 3 2-CF 3
-C
6
H
4
-CH
2 A. 198 C11 3 3-CF 3
-C
6
H
4
-CH
2 A.199 CH 3 4-CF 3
-C
6
H
4
-CH
2 A.200 OH 3 2-acetyl- 6
H
4
-CH
2 A.201 CH 3 3-acetyl-C 6
H
4
-CH
2 A.202 CH 3 4-acetyl- 6
H
4
-CH
2 A. 20 OH -mtoyabn-CH-CH 2 A. 204 OH 3 3-methoxycarbonyl-C 6
H
4
-H
A. 205 OH 3 4-methoxycarbonyl-C 6
H
4
-CH
2 A.205 OH 3 42-mihoxcarbonyl- 6 4
-H
2 A. 207 OH 3 2-aminocarbonyl-C 6
H
4
-CH
2 A.207 OH 3 4-aminocarbony- 6 1 4
-CH
2 A. O 20 CH 3 2-dmetynocarbonyl--O11 2 A.209 OH 3 23-dimethylaminocarbonyl- 6
H
4 -C11 2 A. 211 OH 3 3-dimethylaminocarbonyl-C 6
H
4
-CH
2 A.211 0113 2-(Nmethylaminocarbonyl- 6
H
4
-H
2 A. 213 0113 3-(N-methylaminocarbonyl) -0 6
H
4
-CH
2 A. 214 OH 3 4- (N-methylaminocarbonyl)
-C
6
H
4 -0H 2 A.215 OH 3 2-11 2
N-C
6
H
4
-CH
2 A.216 OH 3 3-11 2
N-C
6
H
4
-CH
2 A.217 CH 3 4-H 2
N-C
6
H
4
-CH
2 A. 218 0113 2 -aminothiocarbonyl- 6 1 4 -1 2 A.219 OH 3 3-alninothiocarbonyl- 6
H
4 -11 2 A. 220 OH 3 4-aminothiocarbonyl-C 6
H
4
-CH
2 A. 221 O'H 3 2-methoxyiminomethyl- 6
H
4 -11 2 A. 222 OH 3 3-methoxyiminomethyl- 6 1 4
-OH
2 A. 223 0113 4-methoxyiminomethyl-C 6 1 4 -1 2 A.224 0113 2-formyl-C 6
H
4
-CH
2 A.225 0113 3-formyl-C 6
H
4 -11 2 A.226 0113 4-formyl-0 6
H
4
-CH
2 A.227 0113 1 -methoxyiminoeth-1 '-yl)-O6H4-OH2 A.228 OH 3 1 -methoxyiminoeth-1 '-Yl)-0 6
H
4
-CH
2 A. 229 0113 4- (1'-methoxyiminoeth-1 '-Yl)-06114-0112 A.230 O'H 3 2-SCH 3
-C
6
H
4 -11 2 A.231 0113 3-SCH 3
-C
6
H
4
-CH
2 A.232 OH 3 4-SCH 3 6 1 4 -011 2 A.233 0113 12-S0 2
CH
3
-C
6
H
4
-CH
2 ii') 0050/46043 118 No.R24 A.234 CH 3 3-SO 2
CH
3
-C
6
H
4
-CH
2 A.235 OH 3 4-.S0 2
CH
3
-C
6
H
4
-CH
2 A.236 OH 3 2-00F 3
-C
6
H
4
-CH
2 A.237 OH 3 3-00F 3
-C
6
H
4
-CH
2 A.238 OH 3 4-00F 3 6
H
4
-CH
2 A.239 OH 3 2-OCHF 2
-C
6
H
4
-CH
2 A.240 OH 3 3-OCHF 2
-C
6
H
4
-CH
2 A.241 OH 3 4-OCHF 2
-C
6
H
4
-CH
2 A. 242 OCH 3 3-OF 3 4-00F 3 6
H
3
-CH
2 A.243 OH 3 1-naphthyl-CH 2 A.244 OH 3 2-naphthyl-CH 2 A.245 OH 3 2-phenoxyeth-1-yl A.246 OCH 3 2-(2'-chlorophenoxy)eth-1-yl A.24-/ OH 3 2-(31-chlorophenoxy)eth-1-yl A.248 OH 3 2-(4'-chlorophenoxy)eth-1-yl A.249 CH 3 2-(3',5-dichlorophenoxy)eth-1-yl A.250 OH 3 2-(2'-cyanophenoxy)eth-1-yl A.251 OH 3 2-(3'-cyanophenoxy)eth-1-yl A.252 OH 3 2-(4'-cyanophenoxy)eth-1-yl A.253 OH 3 2-(2'-methylphenoxy)eth-1-yl A.254 OH 3 2-(3'-methylphenoxy)eth-1-yl A.255 OH 3 2-(4'-methylphenoxy)eth-1-yl A.256 OH 3 2-(3 '-t-butylphenoxy)eth-1-yl A.257 CH 3 2-(4 '-t-butylphenoxy)eth-1-yl A.258 OH 3 2-(2'-nitrophenoxy)eth-1-yl A.259 OH 3 2-(3'-nitrophenoxy)eth-1-yl A.260 OH 3 2-(4'-nitrophenoxy)eth-1-y.
A.261 OH 3 2-(2 '-methoxyphenoxy)eth-1-yl A.262 OH 3 3 -methoxyphenoxy)eth-1-yl A.263 OH 3 2-(4 '-methoxyphenoxy)eth-1-yl A.264 OH 3 2-(2 '-trifluoromethylphenoxy)eth-1-yl A.265 CH 3 2-(3 '-trifluoromethylphenoxy)eth-1-yl A.266 OH 3 4 -trifluoromethylphenoxy)eth-1-y.
A.267 CH 3 2-(2'-acetylphenoxy)eth-1-yl A.268 OH 3 2-(3'-acetylphenoxy)eth-1-yl A.269 OH 3 2-(4'-acetylphenoxy)eth-1-yl A.270 CH 3 2-(2 '-methoxycarbonyl)eth-1-yl A.271 CH 3 3 -methoxycarboriyl)eth-1-yl A.272 OCH 3 12-(4 '-methoxycarbonyl)eth-1-yl ~I '3
I
vo 0050/46043 119 No.R24 A.273 CH 3 2-(2 '-dimethylaminocarbonyl)eth-1-yl A.274 CH 3 2-(3 '-dimethylaminocarbonyl)eth-1-yl A.275 CH 3 2-(4 '-dimethylaminocarbonyl)eth-1-yl A.276 CH 3 2-(2 '-aminothiocarbonyl)eth-1-yl A.277 CH 3 2-(3 '-aminothiocarbonyl)eth-1-yl A.278 CH 3 2-(4 '-aminothiocarbonyl)eth-1-yl A.279 CH 3 2-(2'-methylsulfonyl)eth-1-yl A.280 CH 3 2-(3'-methylsulfonyl)eth-1-yl A.281 ICH 3 2-(4'-methylsulfonyl)eth-1-yl A.282 CH 3 3-phenoxyprop-1-yl A.283 CH 3 3-(2 '-chlorophenoxy)prop-1-yl A. 284 CH 3 3- -chiorophenoxy )prop-1-yl A. 285 CH 3 3- (4 '-chiorophenoxy )prop-1-yl A.286 CH 3 3-(3',5',dichlorophenoxy)prop-1-yl1 A.287 CH 3 3-(2'-cyanophenoxy)prop-1-yl A.288 CH 3 3-(3'-cyanophenoxy)prop-1-yl A.289 CH 3 3-(4'-cyanophenoxy)prop-1-yl A.290 CH 3 3-(2 '-methylphenoxy)prop-1-yl A.291 CH 3 3-(3 '-methylphenoxy)prop-1-yl A.292 CH 3 3-(4 '-methylphenoxy)prop-1-y.
A.293 CH 3 3-(2 '-methoxyphenoxy)prop-1-yl A.294 CH 3 3 -methoxyphenoxy)prop-1-yl A.295 CH 3 4 -methoxyphenoxy)prop-1-yl A.296 CH 3 3-(2 '-trifluoromethylphenoxy)prop-1-yl A. 297 CH 3 3- -trifluoromethyiphenoxy) prop-1-yl A.298 CH 3 3-(4 '-trifluoromethylphenoxy)prop-1-yl A.299 CH 3 4-phenoxybut-1-yl A.300 CH 3 2-phenyleth-1-yl A.301 CH 3 2-(2'-chlorophenyl)eth-1-yl A.302 CH 3 2-(3 '-chlorophenyl)eth-1-yl A.303 CH 3 2-(4'-chlorophenyl)eth-1-yl A.304 CH 3 2-(3',5'-dichlorophenyl)eth-1-yl A.305 CH 3 2-(2'-cyanophenyl)eth-1-yl A.306 CH 3 2-(3'-cyanophenyl)eth-1-yl A.307 CH 3 2-(4'-cyanophenyl)eth-1-yl A.308 CH 3 2-(2'-rnethylphenyl)eth-1-yl A.309 CH 3 2-(3'-methylphenyl)eth-1-yl A.310 CH 3 2-(4'--methylphenyl)eth-1-yl .h'A311 CH 3 12-(2'-methoxyphenyl)eth-1-yl
NC.
0050/46043 120 No.R24 A.312 CH 3 2-(3 '-methoxyphenyl)eth-1-yl A.313 CH 3 2-(4 '-methoxyphenyl)eth-1-yl A.314 ICH 3 2-(2 '-trifluoromethylphenyl)eth-1-yl A. 315 CH 3 2- -trifluoromethyiphenyl )eth-1-yl A.316 CH 3 4 -trifluoromethylphenyl)eth-1-yl A.317 CH 3 3-phenylprop-1-yl A.318 CH 3 3-(2'-chlorophenyl)prop-1-yl A.319 CH 3 3-(3'-chlorophenyl)prop-1-yl A.320 CH 3 3-(4'-chlorophenyl)prop-1-yl A.321 CH 3 3-(2 '-cyanophenyl)prop-1-yl A.322 CH 3 3-(3'-cyanophenyl)prop-1-yl A.323 CH 3 3-(4 '-cyanophenyl)prop-1-yl A.324 CH 3 3-(2 '-trifluoromethylphenyl)prop-1-yl A.325 CH 3 4-pheny2lbut-1-yl A.326 CH 3 4-(4 '-chlorophenyl)but-1-yl A.327 CH 3 6-(4'-chlorophenyl)hex-1-yl A.328 CH 3 2-pyridylmethy.
A.329 CH 3 3-pyridylmethy.
A.330 CH 3 4-pyridylmethyl A. 331 CH 3 4-chloropyridin-2-ylmethyl A. 332 CH 3 5-chloropyridin-2-ylmethyl A. 333 CH 3 6-chloropyridin-2-ylmethy.
A. 334 CH 3 5-chloropyridin-3-ylmethyl A. 335 CH 3 6-chloropyridin-3-ylmethyl A. 336 CH 3 2-chloropyridin-4-ylmethyl A.337 CH 3 2-pyrimidinylmethyl A. 338 CH 3 4-chloropyrimidin-2-ylnethyl A. 339 CH 3 5-chloropyrimidin-2-ylmethyl A. 340 CH 3 2-chloropyrimidin-4-ylmethyl A. 341 CH 3 6-chloropyrimidin-4-ylmethyl A. 342 CH 3 A.343 CH 3 4-pyridazinylmethyl A.344 CH 3 2-pyrazinylmethyl A. 345 CH 3 5-chloropyrazin-2-ylmethyl A. 346 CH 3 6-chloropyrazin-2-ylmethyl A.347 CH 3 3-pyridazinylmethyl A. 348 CH 3 6-chloropyridazin-3-ylmethyl A.349 CH 3 1,3,5-triazinylmethyl A.350 CH 3 2-furylmethyl 0050/46043 121 No.R24 A.351 CH 3 3-furylmethyl A.352 OH 3 4-bromofur-2-ylmethyl A.353 CH 3 5-chlorofur-2--ylmethyl A.354 OH 3 2-thienylmethyl A.355 CH 3 3-thienylmethyl A. 356 CH 3 5-methylthien-3-ylmethyl A. 357 OH 3 5-chlorothien-2-ylmethyl A. 358 OH 3 2-chlorothien-4-ylmethyl A.359 OH 3 2-pyrrolylmethyl A.360 CHI 3-pyrrolylmethyl A.361 CH 3 2-oxazolylmethyl A. 362 OH 3 4-methyloxazol-2-ylmethyl A. 363 OH 3 5-methyloxazol-2-ylmethyl A. 34 CH 3 4-chloro-oxazol-2-ylmethyl A. 365 CH 3 5-chloro-oxazol-2-ylmethyl A.366 CH 3 4-oxazolylmethyl A. 367 OH 3 2-methyloxazol-4-ylmethyl A. 368 OH 3 5-methyloxazol-4-ylmethyl A. 369 OH 3 2-chloro-oxazol-4-ylmethyl A. 370 OH 3 5-chloro-oxazol-4-ylmethyl A.371 CH 3 A. 372 OH 3 A. 373 OH 3 A. 374 CH 3 A. 375 OH 3 A.376 CH 3 2-thiazolylmethyl A. 377 OH 3 4-methylthiazol-2-ylmethy.
A. 378 OH 3 5-methylthiazol-2-ylmethyl A. 379 OH 3 4-chlorothiazol-2-ylmethyl A. 380 OH 3 5-chlorothiazol-2-ylmethyl A.381 OH 3 4-thiazolylmethy.
A. 382 OH 3 2-methylthiazol-4-ylmethyl A. 383 OH 3 5-methylthiazol-4-ylmethyl A.384 OH 3 2 -chlorothiazol-4-ylmethyl A .385 OH 3 5-chlorothiazol-4-ylmethyl A.386 OH 3 A. 387 OH 3 A. 388 OH 3 A. 89 H 3 12-chlorothiazol-5-ylmethyl 0050/46043 122 No.R24 A.390 OH 3 4 A.391 OH 3 3-isoxazolylmethyl A. 392 CH 3 4 -methylisoxazol-3.ylmethyl A. 393 CH 3 5-methylisoxazol-3.ylmethyl A. 394 OH 3 4 -chloro-isoxazol3.ylmethyl A. 395 OH 3 5-chloro-isoxazol3.ylmethyl A.396 CH 3 4 -isoxazolylmetiyl A. 397 OH 3 3 -methylisoxazol4..ylmethyl A. 398 OH 3 5-methylisoxazol-4-ylmethyl A. 399 OH 3 3 -chloro-isoxazol-4-ylmethyl A. 400 OH 3 5-chloro-isoxazol4..ylmethyl A.401 OH 3 A. 402 OH 3 3 A. 403 OH 3 4 A.404 OH 3 3 -chloro-isoxazoZl-5-ylmethyi1 A. 405 CH 3 4 A.406 OH 3 3-isothiazolylmethyl A. 407 OH 3 4 -methyl-isothiazol-3-ylmethyl A. 408 OH 3 5-methyl-isothiazol.3..ylmethyl A.409 OH 3 4-chloro-isothiazol-3 -ylmethyl A. 410 OH 3 5-chloro-isothiazol.3..ylmethyl A.411 OH 3 4-isothiazolylmethyl A. 412 OH 3 3 -methyl-isothiazol4..ylmethyl A.413 OH 3 5-methyl-isothiazol.4 -ylmethyl A. 414 OH 3 3 -chloro-isothiazol.4.ylmethyl A. 415 OH 3 5-chloro-isothiazol.4.ylmethyl A.416 OH 3 A. 417 OH 3 3 A.418 OH 3 4 -methyl-isothiazol-5 -ylmethyl A. 419 OH 3 3 A. 420 OH 3 4 A.421 OH 3 4-imidazolylmethyl A.422 OH 3 1-phenylpyrazol-3 -ylmethyl A. 423 OH 3 l-methylimidazol-4-ylmethyl A. 424 OH 3 I-phenyl-1,2,4-triazol.3..ylmethyl A. 425 OH 3 1,2, 4-oxadiazol-3-ylmethyl A.426 OH 3 5-chloro-1,2, 4 -oxadiazol-3-ylmethyl A.427 O H 3 5-methyl-1,2,4-oxadiazol3..ylmethyl 0050/46043 123 No.R24 A.428 CH 3 5-trifluoromethyl-1, 2,4-oxadiazol-3-yimethyl A. 429 CH 3 1,3, 4-oxadiazol-2-ylmethyl A.430 CH 3 5-chloro-1,3,4-oxadiazol-2-ylmethyl A.431 CH 3 5-methyl-i, 3,4-oxadiazol-2-ylmethyl A.432 CH 3 5-methoxy-1,3,4-oxadiazol-2-yimethyl A. 433 CH 3 1,2, 4-thiadiazol-3-yimethyl A.434 CH 3 5-chloro-1,2,4-thiadiazol-3-ylmethyl A. 435 CH 3 5-methyl-i, 2, 4-thiadiazol-3-ylmethyl A.436 CH 3 1,3, 4-thiadiazol-2-ylmethyl A. 437 CH 3 5-chloro-1, 3, 4-thiadiazol-2-ylmethyl A.438 CH 3 5-methyl-i, 3,4-thiadiazol-2-ylmethyl A.439 CH 3 5-cyano-1, 3,4-thiadiazol-2-ylmethyl
CH
3 2 2-(2'-pyridinyloxylpfh-l-ui A.441 CH 3 2-(3'-pyridinyloxy)eth-1-yl A.442 CH 3 2-(4'-pyridinyloxy)eth-1-yl A.443 CH 3 2-(2 '-pyrimidinyloxy)eth-1-yl A.444 CH 3 2-(4 '-pyrimidinyloxy)eth-1-yl A.445 CH 3 2-(5 '-pyrimidinyloxy)eth-1-yl A.446 CH 3 2-(2'-pyrazinyioxy)eth-l-yi A.447 CH 3 2-(2'-pyridazinyloxy)eth-1-yl A.448 CH 3 2-(3'-pyridazinyloxy)eth-1-yl A.449 CH 3 2-(1',3',5'-triazinyloxy)eth-1-yi A.450 CH 3 2-(5'-methylisoxazol-3 '-yloxy)eth-1-yl A.451 CH 3 5 -chloro-isoxazol-3 '-yloxy)eth-1-yl A.452 CH 3 2-(2 '-methoxythiazol-4 '-yioxy)eth-1-yl A.453 CH 3 2-(4 '-chloro-oxazol-2 '-yloxy)eth-1-yl A.454 CH 3 2-(1'-phenyi-l'H-1',2',4'-triazol-3'-yloxy)eth-1-yl A.455 CH 3 1 -phenylpyrazol-3 '-yloxy)eth-1-yl A.456 CH 3 C 6
H
A.457 CH 3 2-Cl-C 6
H
4 A.458 CH 3 3-C1-C 6
H
4 A.459 CH 3 4-Cl-C 6
H
4 A.460 CH 3 2,3-C1 2
-C
6
H
3 A.461 CH 3 2,4-Cl 2
-C
6
H
3 A.462 OH 3 2,5-Cl 2
-C
6
H
3 A.463 OH 3 3,4-Cl 2
-C
6
H
3 A.464 CH 3 3,5-Cl 2
-C
6
H
3 A.465 ICH 3 4-CN-C 6
H
4 0050/46043 124 No.R24 A.466 CH 3 2-N0 2
-C
6
H
4 A.467 CH 3 3-N0 2
-C
6
H
4 A.468 CH 3 4-N0 2
-C
6
H
4 A.469 CH 3 2,4-(N0 2 2
-C
6
H
3 A.470 CH 3 2-CH 3
-C
6
H
4 A.471 CH 3 3-CH 3
-C
6
H
4 A.472 CH 3 4-CH 3
-C
6
H
4 A.473 CH 3 2,3-(CH 3 2
-C
6
H
3 A.474 CH 3 2,4-(CH 3 2
-C
6
H
3 A.475 CH 3 2,5-(CH 3 2
-C
6
H
3 A.476 CH 3 2,6-(CH 3 2
-C
6
H
3 A.477 ICH 3 2-C 6
H
5
-C
6
H
4 A.478 CH 3 3-C 6
H
5
-C
6
H
4 A.479 CH 3 4-LC 6 i 5
-C
6
H
4 A.480 CH 3 3-OCH 3
-C
6
H
4 A.481 CH 3 4-OCH 3
-C
6
H
4 A.482 CH 3 3-acetyl-C 6
H
4 A.483 CH 3 4-acetyl-C 6
H
4 A.484 CH 3 3-methoxycarbonyl-C 6
H
4 A.485 CH 3 4-methoxycarbonyl-C 6
H
4 A.486 CH 3 3-CF 3
-C
6
H
4 A.487 CH 3 4-CF 3
-C
6
H
4 A.488 CH 3 2-naphthyl A.489 CH 3 6-chloropyridazin-3-yl A.490 CH 3 5-chloropyrazin-2-yl A.491 CH 3 quinolin-2-yl A. 492 CH 3 2, 5-dimethylpyrazin-3-yl A.493 CH 3 pyrazin-2-yl A.494 CH 3 3-chloropyrid-2-yl A.495 CH 3 6-chloropyrid-2-yl A.496 CH 3 4-trifluoromethyl, 6-chloropyrid-2-yl A. 497 CH 3 4-trifluoromethylpyrid-2-yl A. 498 CH 3 6-trifluoromethylpyrid-2-yl A.499 CH 3 6-methoxypyrid-2-yl A.500 CH 3 5-chloropyrid-2-yl A.501 OH 3 pyrid-2-y.
A.502 CH 3 benzothiazol-2-yl A.503 cH 3 7-chloroquinolin-4-yl A.504 CH 3 13-nitropyrid-2-yl 0050/46043 125 No.R24 A.505 CH 3 pyrrol-3-yl A.506 CH 3 pyrrol-2-yl A. 507 en 3 2,6-dioctylpyrid-4-yl A.508 CH 3 5-nitropyrid-2-yl A.509 en 3 pyrid-4-yl A.510 C11, pyrid-3-yl A.511 CH 3 pyrimidin-2-yl A.512 CH 3 pyrimidin-4-yl A.513 CH 3 quiriazolin-4-yl A.514 CH 3 6-chloropyrimidin-4-yl A.515 CH 3 6-methoxypyrimidin-4-yl A.516 CH 3 2,5, 6-trichloropyrimidin-4-yl A. 517 CH 3 2, 6-dimethylpyrimidin-4-yl A.518 en 3 2-methyl, 6-chloropyrimidin-4-yl A. 519 CH 3 2-methyl, 6-ethoxypyrimidin-4-yl A. 520 CH 3 4,5, 6-trichloropyrimidin-2-yl A. 521 CH 3 4, 6-dimethoxypyrimidin-2-yl A. 522 CH 3 4, 6-dimethylpyrimidin-2-yl A. 523 CH 3 4, 6-dichloropyrimidin-2-yl A.524 CH 3 4-methyl, 6-methoxypyrimidin-2-yl A. 525 en 3 4-chioro, 6-methoxypyrimidin-2-yl A.526 CH 3 6-chloroquinoxalin-2-yl A.527 CH 3 3,6-dichloro-1,2,4-triazin-5-yl A. 528 CH 3 4-methoxy-1, 3, 5-triazin-2-yl A.529 CH 3 4-ethoxy-1,3,5-triazin-2-yl A.530 en 3 4,6-dichloro-1,3,5-triazin-2-yl A.531 C'H 3 4-ethoxy, 6-chloro-1,3,5-triazin-2-yl A.532 CH 3 isoxazol-3-yl_ A.533 en 3 thien-2-yl A.534 CH, fur-2-yl A.535 CH 3 A.536 CH 3 (E)-1-chloropropen-3-yl A.537 CH 3 (E)-4-(4'-chlorophenyl)but-2-en-1-yl A.538 CH 3 propyn-3-yl A.539 CH 3 methylcarbonyl A.540 Cen 3 ethylcarbonyl A.541 CH 3 n-propylcarbonyl A.542 CH 3 i-propylcarbonyl A.543 CH 3 in-butylcarbonyl 0050/ 46043 126 No.R24 A.544 CH 3 s-butylcarbonyl A.545 CR 3 i-butylcarbonyl A.546 CR 3 t-butylcarbonyl A.547 CR 3 n-pentylcarbonyl A.548 CR 3 i-pentylcarbony.
A.549 CR 3 neo-pentylcarbonyl A.550 CR 3 n-hexylcarbonyl A.551 CR 3 n-octylcarbony.
CH 1-propenylcarbonyl A.553 CR 3 2-penten-1-ylcarbonyl A. 554 CR 3 2, 5-heptadien-1-ylcarbonyl
CR
3 benzoyl A. 56 CR 3 2-chlorobenzoyl Lut 3 6-cnJlorobenzoy.
A.558 CR 3 4-chlorobenzoyl A.559 CR 3 2-cyanobenzoy.
A.560 CR 3 3-cyanobenzoyl A.561 CR 3 4-cyanobenzoyl A.562 CR 3 4-methoxybenzoyl A.563 CRH 3 2-pyridylcarbonyl A.564 CR 3 3-pyridylcarbonyl A.565 CR 3 4-pyridylcarbonyl A.566 CRH 3 2-pyrimidinylcarbony.
A.567 CR 3 2-oxazolylcarbonyl A. 568 CR 3 A.569 CR 3 methylsulfonyl A.570 CR 3 ethylsulfony.
A.571 CR 3 n-propylsulfonyl A.572 cR 3 i-propylsulfonyl A.573 CR 3 n-butylsulfonyl A.574 CR 3 t-butylsulfonyl A.575 CR 3 n-pentylsulfonyl A.576 CR 3 neo-pentylsulfonyl A.577 CR 3 n-hexylsulfonyl A.578 CR 3 n-octylsulfonyl A.579 CR 3 phenylsulfonyl A.580 CR 3 2-chlorophenylsulfonyl A.581 CR 3 3-chlorophenylsulfonyl A-582 ICR 3 4-chlorophenylsulfonyl 0050/46043 127 No.R24 A.583 OH 3 2-cyanophenylsulfonyl A. 584 CH 3 3-cyanophenylsulfonyl A.585 OH 3 4-cyanophenylsulfonyl A.586 CH 3 2-pyridylsulfonyl A.587 CH 3 3-pyridylsulfonyl A.588 CH 3 4-pyridylsulfonyl A.589 OH 3 2-pyrimidinylsulfonyl A.590 CH 3 4-oxazolylsulfonyl A. 591 CH 3 5-chlorothiazol-2ylsulfonyl A.592 OH 3 2-t- 4
H
9 6
H
4
-CH
2 A.593 OH 3 3-t- 4
H
9 6
H
4
-CH
2 A.594 CH 3 4-t- 4
H
9 6
H
4
-CH
2 A.595 OH 3 2-(4 '-chlorothiazol-2 '-yloxy)eth-1-yl A.596 OH 3 1 -methyipyrazoi-4 '-yioxy)eth-1-yl A.597 CH 3 4-Br-C 6
H
4 A.598 OH 3 3,5-(CH 3 2 -0 6
H
3 A.599 CH 3 4-C 2
H
5
-C
6
H
4 A. 600 OH 3 3-dimethylaminocarbonyl-C 6
H
4 A. 601 OH 3 4-dimethylaminocarbonyl-0 6
H
4 A.602 CH 3 2-hydroxyprop-1-y.
A. 603 CH 3 6-hydroxy-2-methylpyrimidin-4-ylmethyl A.604 CH 3 [6-OH,2-CH(CH 3 2 -pyrimidin-4-ylJ-CH 2 A.605 OH 3 [6-OH,2-CH(CH 2 2 -pyrimidin-4-yl]-CH 2 A.606 OH 3 5-(2'-furan)-pent-1-yl A.607 OH 3 5-(2 '-N-methylpyrrol)-pent-1-yl A.608 OH 3 [2-(4-C1-C 6
H
4 )-oxazol-4-yl]-CH 2 A.609 OH 3 3-CF 3 -pyridin-2-yl A.610 OH 3 5-CF 3 -pyridin-2-yl A.611 CH 3 6-(2'-thienyl)hex-1-yl A.612 OH 3 (E)-3-chlorobut-2-en-1-y.
A. 613 O'H 3 (Z )-3-chlorobut-2-en-1-yl A. 614 OH 3 (E )-2-bromobut-2-en-1-yl A. 615 CH 3 (Z )-2-bromobut-2-en-1-yl A.616 OH 3 I (E)-l-chloroprop-l-en-3-yl A. 617 OH 3 (Z chloroprop-1-en-3-yl A.618 OH 3 but-l-en-3-yl A.619 OH 3
OH
2
OH
2 Br A.620 OCH 3
OH
2
CH
2
CH
2 Br A.621 OCH 3
CH
2
CH
2
CH
2
OH
2 Br IX 6 0050/46043 128 No.R24 A.622 CH 3 2-methoxyprop-1-yl A.623 CH 3 2-ethoxyprop-1-y.
A.624 CH 3 2-isopropoxyprop-1-yl A.625 CH 3 but-1--yn-3-yl A.626 CH 3 but-1-yn-4-yl A.627 CH 3 but-2-yn-4-yl A.628 CH 3 pent-1-yn-4-yl A.629 CH 3 pent-2-yn-4-yl A.630 CH 3 A.631 CH 3 A.632 CH 3 E-2-chlorobut-2-en-1-yl A.633 CH 3 Z-2-chlorobut-2-en-1-yl A. 634 CH 3 Z-1-chloroprop-l-en-3-yl A.635 C 3 2-methylprop-i-en-3-yl A.636 CH 3 2-chloroprop-1-en-3-yl A.637 CH 3 2-bromoprop-l-en-3-yl A.638 CH 3 but-2-en-1-y.
A.639 CH 3 but-3-en-1-yl A.640 CH 3 1-iodoprop-1-yn-3-yl A.641 CH 3 E-3-bromobut-2-en-1-yl A.642 CH 3 Z-3-bromobut-2-en-1-yl A.643 C 2
H
5
H
A.644 C 2
H
5 CH 3 A.645 C 2
H
5 C 2
H
A.646 C 2
H
5 n-C 3
H
7 A.647 C 2
H
5 i-C 3
H
7 A.648 C 2
H
5 cyclopropyl A.649 C 2
H
5 n-C 4
H
9 A.650 C 2
H
5
S-C
4
H
9 A.651 C 2
H
5 i-C 4
H
9 A.652 C 2
H,
5 t-C 4
H
9 A.653 C 2
H
5 n-C 5
H
11 A.654 C 2
H-
5 i-C 5 Hll A.655 C 2
H
5 neo-C 5
H
11 A.656 C 2
H
5 cyclopentyl A.657 C 2
H
5 n-C 6 Hl 3 A.658 C 2
H
5 cyclohexyl A.659 C 2
H
5 n-C 8 Hl 7 A.660 C 2
H
5 ICH 2
CH
2 Cl 0050/46043 129 No.R24 A.661 C 2
H
5 (CH 2 4 Cl A.662 C 2
H
5 CH 2
CN
A.663 C 2
H
5 CH 2
CH
2
CN
A.664 C 2
H
5 (CH 2 3
CN
A.665 C 2
H
5 (0H 2 4
CN
A.666 C 2
H
5 (CH 2 6
CN
A.667 C 2
H
5 cyclohexylmethyl A.668 C 2
H
5 2-cyclohexyleth-1-yl A.669 C 2
H
5 cyclopropylmethyl A.670 C 2
H
5 2-cyclopropyleth-1-yl A.671 C 2
H
5 2-methoxyeth-1-yl A.672 C 2
H
5 2-ethoxyeth-1-y.
A.673 C, 2
H
5 2-isopropoxyeth-1-yl A.674 C 2
H
5 3 -mtethoxyprop-i-yl A.675 C 2
H
5 3-ethoxyprop-1-yl A.676 C 2
H
5 3-isopropoxyprop-1-yl A.677 C 2
H
5 4-methoxybut-1-yl A.678 C 2
H
5 4-isopropoxybut-1-yl A.679 C 2
H
5 propen-3-yl A.680 C 2
H
5 but-2-en-1-yl A.681 C 2
H
5 3-methylbut-2-en-1-yl A.682 C 2
H
5 2-vinyloxyeth-1-yl A.683 C 2
H
5 allyloxyeth-1-yl A. 684 C 2
H
5 2-trifluoromethoxyeth-1.yl A. 685 C 2
H
5 3-trifluoromethoxyprop-1-yl A. 686 C 2
H
5 4-difluoromethoxybut-1-yl A.687 C 2
H
5 hydroxycarbonylmethyl A.688 C 2
H
5 methoxycarbonylmethyl A.689 C 2
H
5 aminocarbonylmethyl A.690 C 2
H
5 N-methylaminocarbonylmethyl A. 691 C 2
H
5 N,N-dimethylaminocarbonyl.methyl A. 692 C 2
H
5 2-hydroxycarbonyleth-1..yl A. 693 C 2
H
5 2-methoxycarbonyeth-1..yi A.694 C 2
H
5 2-amin ocarbonyleth-1-.yl A. 695 C 2
H
5 2 -N-methylaminocarbonyleth-1..yl A. 696 C 2
H
5 2-dimethylaminocarbonyleth-1.yl A.697 C 2 11 5 2-aminoeth-1-yl A.698 C 2
H
5 2-aminoprop-1-yl A.699 IC 2
H
5 4-axninobut-1-yl 0050/46043 130 No.R24 A. 700 C 2
H
5 3-dimethylaminoprop-1-yl A.7 701 C 2
H
5 4-aminothiocarbonylbut-1-yl A.702 C 2
H
5 2-oxopropyl A.703 C 2
H
5 cyclohexyl A.704 C 2
H
5 cyclopropyl A.705 C 2
H
5 cyclopentyl A. 706 C 2
H
5 2-iethoxyiminoprop-1-yl A.707 ICqHq 2-methoxyiminoeth-1-yl A.708 C 2
H
5 6-aminocarbonylhex-1-yl A. 709 C 2
H
5 3-aminothiocarbonylprop-1-yl A. 710 C 2
H
5 2-aminothiocarbonyleth-1-yl A.711 C 2
H
5 aminothiocarbonylmethyl A.712 C 2
H
5 4-(N,N-dimethylamino)but-1-yl A. 7 13 C, 2
H
5 2- (m-ethylthio )eth-1-y.
A.714 C 2
H
5 2-(methylsulfonyl)eth-1-yl A.715 C 2
H
5 4-(methylthio)prop-1-yl A.716 C 2
H
5 4-(methylsulfonyl)prop-1-yl A.717 C 2
H
5 benyzi A.718 C 2
H
5 2-F-C 6
H
4
-CH
2 A.719 C 2
H
5 3-F-C 6
H
4
-CH
2 A.720 C 2
H
5 4-F-C 6
H
4
-CH
2 A.721 C 2
H
5 2,3-F 2
-C
6
H
3
-CH
2 A.722 C 2
H
5 2,4-F 2
-C
6
H
3
-CH
2 A.723 C 2
H
5 2,5-F 2
-C
6
H
3
-CH
2 A.724 C 2
H
5 2,6-F 2
-C
6
H
3
-CH
2 A.725 0 2
H
5 3,4-F 2
-C
6
H
3
-CH
2 A.726 C 2
H
5 3,5-F 2
-C
6
H
3
-CH
2 A.727 C 2
H
5 2-Cl-C 6
H
4
-CH
2 A.728 C 2
H
5 3-Cl-C 6
H
4
-CH
2 A.729 C 2
H
5 4-C1-C 6
H
4
-CH
2 A.730 C 2
H
5 2,3-C 2
-C
6
H
3
-CH
2 A.731 C 2
H
5 2,4-C 2
-C
6
H
3
-CH
2 A.732 C 2
H-
5 2,5-C1 2
-C
6
H
3
-CH
2 A.733 C 2
H
5 2,6-C1 2
-C
6
H
3
-CH
2 A.734 C 2
H
5 3,4-C1 2
-C
6
H
3
-CH
2 A.735 C 2
H
5 3,5-C 2
-C
6
H
3
-CH
2 A.736 C 2
H
5 2,3,4-C 3
-C
6
H
2
-CH
2 A.737 C 2
H
5 2,3,5-Cl 3
-C
6
H
2
-CH
2 A.738 jC 2
H
5 2,3,6-Cl 3
-C
6
H
2
-CH
2 0050/46043 131 No.R24 A.739 C 2
H
5 2,4, 5-Cl 3
-C
6
H
2
-CH
2 A.740 C 2
H
5 2,4,6-Cl 3
-C
6
H
2
-CH
2 A.741 JC 2
H
5 3,4,5-Cl 3
-C
6
H
2
-CH
2 A.742 C 2
H
5 2-Br-C 6
H
4
-CH
2 A.743 CAS 5 3-Br-C 6
H
4
-CH
2 A.744 C 2
H
5 4-Br-C 6
H
4
-CH
2 A.745 C 2
H
5 2,3-Br 2
-C
6
H
3
-CH
2 A.746 C 2
H
5 2,4-Br 2
-C
6
H
3
-CH
2 A.747 C 2
H
5 2,5-Br 2
-C
6
H
3
-CH
2 A.748 C 2
H
5 2,6-Br 2
-C
6
H
3
-CH
2 A.749 C 2
H
5 3,4-Br 2
-C
6
H
3
-CH
2 A.750 C 2
H
5 3,5-Br 2
-C
6
H
3
-CH
2 A.751 C 2
H
5 2-F, 3-Cl-C 6
H
3
-CH
2 A. 752 2 n 5 2-F, CH 3
-CH
2 A.753 C 2
H
5 2-F, 5-Cl-C 6
H
3
-CH
2 A.754 C 2
H
5 2-F, 3-Br-C 6
H
3
-CH
2 A.755 CAS 5 2-F, 4-Br-C 6
H
3
-CH
2 A.756 C 2
H
5 2-F, 5-Br-C 6
H
3
-CH
2 A.757 C 2
H
5 2-Cl, 3-Br-C 6
H
3
-CH
2 A.758 C 2
H
5 2-Cl, 4-Br-C 6
H
3
-CH
2 A.759 C 2
H
5 2-Cl, 5-Br-C 6
H
3
-CH
2 A.760 C 2
H
5 3-F, 4-Cl-C 6
H
3
-CH
2 A.761 C 2
H
5 3-F, 5-Cl-C 6
H
3
-CH
2 A.762 C 2
H
5 3-F, 6-Cl-C 6
H
3
-CH
2 A.763 C 2
H
5 3-F, 4-Br-C 6
H
3
-CH
2 A.764 C 2
H
5 3-F, 5-Br-C 6
H
3
-CH
2 A.765 C 2
H
5 3-F, 6-Br-C 6
H
3
-CH
2 A.766 C 2
H
5 3-Cl, 4-Br-C 6
H
3
-CH
2 A.767 C 2
H
5 3-Cl, 5-Br-C 6
H
3
-CH
2 A.768 C 2
H
5 3-Cl, 6-Br-C 6
H
3
-CH
2 A.769 C 2
H
5 4-F, 5-Cl-C 6
H
3
-CH
2 A.770 C 2
H
5 4-F, 6-Cl-C 6
H
3
-CH
2 A.771 C 2
H
5 4-F, 5-Br-C 6
H
3
-CH
2 A.772 C 2
H
5 4-F, 6-Br-C 6
H
3
-CH
2 A.773 C 2
H
5 4-Cl, 5-Br-C 6
H
3
-CH
2 A.774 C 2
H
5 5-F, 6-Cl-C 6
H
3
-CH
2 A.775 C 2
H
5 5-F, 6-Br-C 6
H
3
-CH
2 A.776 C 2
H
5 5-Cl, 6-Br-C 6
H
3
-CH
2 A.777 C 2
H
5 13-Br, 4-Cl, 5-Br-C 6
H
2
-CH
2 0050/46043 132 No.R24 A. 778 C 2
H
5 2-CN-C 6
H
4
-CH
2 A.779 C 2
H
5 3-CII-C 6
H
4
-CH
2 A.780 C 2
H
5 4-CN-C 6
H
4
-CH
2 A.781 C 2
H
5 2-N0 2
-C
6
H
4
-CH
2 A.782 C 2
H
5 3-N0 2
-C
6
H
4
-CH
2 A.783 C 2
H
5 4-N0 2
-C
6
H
4
-CH
2 A.784 C 2
H
5 2-CH 3
-C
6
H
4
-CH
2 A. 785 C 2
H
5 3-CH 3
-C
6
H
4
-CH
2 A.786 C 2
H
5 4-CH 3
-C
6
H
4
-CH
2 A.787 C 2
H
5 2,3-(CH 3 2
-C
6
H
3
-CH
2 A.788 C 2
H
5 2,4-(CH 3 2
-C
6
H
3
-CH
2 A.789 C 2
H
5 2,5-(CH 3 2
-C
6
H
3
-CH
2 A.790 C 2
H
5 2 ,6-(CH 3 2
-C
6
H
3
-CH
2 A.791 2
H
5 1, 4- CH 3 2
-C
6
H
3
-CH
2 A.792 C 2
H
5 3,5-(CH 3 2
-C
6
H
3
-CH
2 A-793 C 2
H
5 2-C 2
H
5
-C
6
H
4
-CH
2 A.794 C 2
H
5 3-C 2
H
5
-C
6
H
4
-CH
2 A.795 C 2
H
5 4-C 2
H
5
-C
6
H
4
-CH
2 A.796 C 2
H
5 2-i-C 3
H
7
-C
6
H
4
-CH
2 A.797 0 2
H
5 3-i-C 3
H
7
-C
6
H
4
-CH
2 A.798 C 2 HS 4-i-C 3
H
7
-C
6
H
4
-CH
2 A.799 C 2
H
5 2-cyclohexyl-C 6
H
4
-CH
2 A.800 C 2
H
5 3-cyclohexyl-C 6
H
4
-CH
2 A.801 0 2
H
5 4-cyclohexyl-C 6
H
4
-CH
2 A.802 C 2
H
5 2-vinyl-C 6
H
4
-CH
2 A.803 C 2
H
5 3-vinyl-C 6
H
4
-CH
2 A.804 C 2
H
5 4-vinyl-C 6
H
4
-CH
2 A.805 C 2
H
5 2-allYl-C 6
H
4
-CH
2 A.806 C 2
H
5 3-allYl-C 6
H
4
-CH
2 A.807 C 2
H
5 4-allYl-C 6
H
4
-CH
2 A.808 C 2
H
5 2-C 6
H
5
-C
6
H
4
-CH
2 A.809 C 2
H
5 3-C 6
H
5
-C
6
H
4
-CH
2 A.810 0 2
H
5 4-C 6
H
5
-C
6
H
4
-CH
2 A.811 C 2
H
5 3-CH 3 5-t-C 4
H
9
-C
6
H
3
-CH
2 A.812 C 2
H
5 2-OH-C 6
H
4
-CH
2 A.813 C 2
H
5 3-OH-C 6
H
4
-CH
2 A.814 C 2
H
5 4-OH-C 6
H
4
-CH
2 A.815 C 2
H
5 2-OCH 3
-C
6
H
4
-CH
2 A.816 C 2
H
5 3-OCH 3
-C
6
H
4
-CH
2 0050/46043 133 No.R24 A. 817 C 2
H
5 4-OCH 3
-C
6
H
4
-CH
2 A. 818 C 2
H
5 2 ,3-(OCH 3 2
-C
6
H
3
-CH
2 A.819
C
2
H
5 2 4
-(OCH
3 2
-C
6
H
3
-CH
2 A.820
C
2
H
5 2
(CH
3 2
-C
6
H
3
-CH
2 A.821
C
2
H
5 3 4
(OCH
3 2
-C
6
H
3
-CH
2 A.822
C
2
H
5 35(C32CH-H A.823
C
2
H
5 3 4 (OCH3) 3
-C
6
H
2
-CH
2 A.824
C
2
H
5 2-QC2H5-C 6
H
4
-CH
2 A.825
C
2
H
5 3-OC2H5-C 6
H
4
-CH
2 A.826
C
2
H
5 4-OC2H5-C 6
H
4
-CH
2 A. 827 C 2
H
5 2-0- (n-C 3
H
7
-C
6
H
4
-CH
2 A. 828 C 2
H
5 3-0- (n-C 3
H
7
-C
6
H
4
-CH
2 A.829
C
2
H
5 4 (-C3H 7
)-C
6 4
CH
2 Az830
C
2
H
5 Z-U-tI-C3H7)-C 6
H
4
.CH
2 A.831
C
2
H
5 3 (i-C3H 7
-C
6
H
4
-CH
2 A.832
C
2
H
5 CHC2 A. 833 C 2
H
5 4-0- (n-C 4
H
9
-C
6
H
4
-CH
2 A.834
C
2
H
5 CHC2 A.835
C
2
H
5 4 (n-C 6
H
3
-C
6
H
4
-C.H
2 A.836
C
2
H
5 2 -0-allYl-C 4
-CH
2 A.837 IC 2
H
5 3 -O-allYl-CH 4
-CH
2 a QlQ I," A. 839 A.840 A. 841 A.842 A. 843 A.844 A. 845 A. 846 A. 847 A.848 A.849 A. 850 A.851 A. 852 A. 853 A. 854 A 855 7
C
2
H
5 4~-0-allYl-C0H 4
-CH
2 2-cF 3
-C
6
H
4
-CH
2
C
2
H
C
2
H
5
C
2
H
5
C_
2
H
C
2
H
5
C
2
H
5
C
2
H
5
C
2
H
5
C
2
H
5
C
2
H
5
C
2
H
5
C
2
H
5
C
2
H
5
C
2
H
5
C
2
H
5
C
2
H
5 I F3C64-H 4-CF 3
-C
6
H
4
-CH
2
I
2 -acetyl-CH 4
-CH
2 acetyl-CH 4
-CH
2 4-acetyl-C 6
H
4
-CH
2 2 -methoxycarbonylC 6
H
4
.CH
2 3 -methoxycarbonyl-C 6
H
4
-CH
2 4 -ne t hoxyc arbo ny 1 C 6
H
4 CH 2 2 ami no carb ony- C 6 H 4 C H 2 3 -aminocarbony-C 6
H
4
-CH
2 4 ami noc arbo ny 1-C 6 H 4 -CH 2 2 -dimethylaminocarbonyl.C 6
H
4
-CH
2 3 -dimethylaminocarbonylC 6
H
4
-CH
2 4 -d ime th yam in o car bo ny1 C 6 H 4 -C H 2 2 N-me thy 1ami no carbo ny 1 -C 6 H 4 CH 2 3- (N-xethylaminocarbonyl )-C6H4-CH2 0050/46043 134 No.R24 A. 856 C 2
H
5 4 -(N-methylaminocarbonyl
)C
6
H
4
.CH
2 A.857 C 2
H
5 2-H 2 Iq-C 6
H
4
-CH
2 A.858
C
2
H
5 3-H 2
N-C
6
H
4
-CH
2 A.859
C
2
H
5 4-H 2
N-C
6
H
4
-CH
2 A.860 C 2
H
5 2 -aminothiocarbonyl-C 6
H
4
-CH
2 A. 861 C 2
H
5 3 -aminothiocarbonyl-C 6
H
4
.CH
2 A. 862 C 2
H
5 4-aminothiocarbonyl-C 6
H
4
-CH
2 A. 863 C 2
H
5 2 -methoxyiminometylC 6
H
4
CH
2 A. 864 C 2
H
5 3 -methoxyiminomethylC 6
H
4
CH
2 A.865 C 2
H
5 4 -methoxyiminomethyl.C 6
H
4 -CH1 2 A.866
C
2
H
5 2-formyl-C 6
H
4
-CH
2 A.867
C
2
H
5 3-formyl-C 6
H
4
-CH
2 A.868 C 2
H
5 4-formyl-C 6
H
4
-CH
2 A.6 Tfft -moximnet-lY)C64-H A. 870 C 2
H
5 3-(1 1 '-methoxyiminoeth-
-C
6
H
4
-CH
2 A. 871 C 2
H
5 1 -methoxyiminoeth-1 '-Yl)-C 6
H
4
-CH
2 A.872 C 2
H
5 2-SCH 3
-C
6
H
4
-CH
2 A.873 C 2
H
5 3-SCH 3
-C
6
H
4
-CH
2 A.874 C 2
H
5 4-SCH 3
-C
6
H
4
-CH
2 A.875 C 2
H
5 2-SO 2
CH
3
-C
6
H
4
-CH
2 A.876 C 2
H
5 3-SO 2
CH
3
-C
6
H
4
-CH
2 A.877 C 2
H
5 4-SO 2
CH
3
-C
6
H
4
-CH
2 A.878 C 2
H
5 2-OCF 3
-C
6
H
4
-CH
2 A.879 C 2
H
5 3-OCF 3
-C
6
H
4
-CH
2 A.880 C 2
H
5 4-OCF 3
-C
6
H
4
-CH
2 A.881 C 2
H
5 2-OCHF 2
-C
6
H
4
-CH
2 A.882 C 2
H
5 3-OCHF 2
-C
6
H
4
-CH
2 A.883
C
2
H
5 4 -OCHF 2
-C
6
H
4
-CH
2 A.884 C 2
H
5 3-CF 3 4-OCF 3
-C
6
H
3
-CH
2 A.885 C 2
H
5 1-naphthyl-CH 2 A.886 C 2
H
5 2-naphthyl-CH 2 A.887 C 2
H
5 2-phenoxyeth-1-yl A.888 C 2
H
5 q 2- -chiorophenoxy) eth-1-yl A.889 C 2
H
5 2 3 '-chlorophenoxy)eth-.1.yl A.890 C 2
H
5 2 -(4'-chlorophenoxy)eth-1-yl A.891 C 2
H
5 2 3 5 -dichlorophenoxy)eth1.yl A.892 C 2
H
5 2 2 '-cyanophenoxy)eth-1..yl A-893 jC 2
H
5 2 3 '-cyanophenoxy)eth-1..yl A.894 C 2 5 2 -(4'-cyanophenoxy)eth-1d.yl 0 0050/46043 135 No. R 2
R
A.895 C 2
H
5 2-(2'-methylphenoxy)eth-1-yl A.896 C 2
H
5 2-(3'-methylphenoxy)eth-1-yl A.897 C 2
H
5 2-(4'-methylphenoxy)eth1.yl A.898 C 2
H
5 2 -(3'-t-butylphenoxy)eth-1-yl A.899 C 2
H
5 2-(4'-t-butylphenoxy)eth-1-yl A.900 iCHq 2-(2'-nitrophenoxy)eth-1-yl A.901 C 2
H
5 2-(3'-rlitrophenoxy)eth-1-yl A.902 C 2
H
5 2-(4'-nitrophenoxy)eth-1-yl A.903 C 2
H
5 2-(2 '-methoxyphenoxy)eth-1-yl A.904 C 2
H
5 2-(3'-methoxyphenoxy)eth-1-yl A.905 C 2
H
5 2-(4 '-methoxyphenoxy)eth-1-yl A. 906 C 2
H
5 2-(2 '-trifluoromethylphenoxy)eth.1.yl A.907 C 2
H
5 2-(3 '-trifluoromethylphenoxy)eth-1.yl A.908 C 2
H
5 2-('-t'rif-iuoromethyiphenoxy)eth-1-y.
A.909 C 2
H
5 2-(2 '-acetylphenoxy)eth-1-yl A.910 C 2
H
5 2-(3'-acetylphenoxy)eth-1-yl A.911 C 2
H
5 2-(4'-acetylphenoxy)eth-1-yl A.912 C 2
H
5 2-(2 '-methoxycarbonylL)eth-1-yl A.913 C 2
H
5 2-(3 '-methoxycarbonyl)eth-1-y.
A. 914 C 2
H
5 2-(4 '-methoxycarbonyl)eth-1-y.
A.915 C 2
H
5 2-(2 '-dimethylaminocarbonyl)eth-1-yl A. 916 C 2
H
5 2-(3 '-dimethylaminocarbonyl)eth-1-yl A. 917 C 2
H
5 2-(4 '-dixethylaminocarbonyl)eth-1-yl A. 918 C 2
H
5 2-(2 '-aminothiocarbonyl)eth-1-yl A. 919 C 2
H
5 2-(3 '-aminothiocarbonyl)eth-1-yl A.920 C 2
H
5 2-(4 '-aminothiocarbonyl)eth-1-yl A.921 C 2
H
5 2-(2'-methylsulfonyl)eth-1-yl A.922 C 2
H
5 2-(3'-methylsulfonyl)eth-1-yl A.923 C 2
H
5 2-(4 '-methylsulfonyl)eth-1-yl A.924 C 2
H
5 3-phenoxyprop-1-yl A. 925 IC 2
H
5 3-(2 '-chlorophenoxy)prop-1-yl A.926 C 2
H
5 3-(3'-chlorophenoxy)prop-1-yl A.927 C 2
H
5 3-(4 '-chlorophenoxy)prop-1-yl A.928 C 2
H
5 3-(3',5',dichlorophenoxy)prop-1-y.
A.929 C 2
H
5 3-(2'-cyanophenoxy)prop-1-yl A.930 C 2
H
5 3-(3'-cyanophenoxy)prop-1-yl A.931 C 2
H
5 3-(4'-cyanophenoxy)prop-1-yl A.932 jC 2
H
5 3-(2'-methylphenoxy)prop-1-yl 933 C~ 5 3-(3'-methylphenoxy)prop-1-yl 0050/46043 136 No.R24 A.934 C 2
H
5 3-(4'-methylphenoxy)prop-1-yl A.935 C 2
H,
5 3-(2 '-methoxyphenoxy)prop-1-y.
A.936 C 2
H.
5 3-(3 '-methoxyphenoxy)prop-1-yl A.937 C 2
H
5 3-(4 '-methoxyphenoxy)prop-1-yl A.938 C 2
H
5 3-(2 '-trifluoromethylphenoxy)prop-1-yl A.939 C 2
H
5 3-(3 '-trifluoromethylphenoxy)prop-1-yl A.940 C 2
H
5 3-(4 '-trifluoromethylphenoxy)prop-1-yl A.941 C 2
H
5 4-phenoxybut-1-yl A.942 C 2
H
5 2-phenyleth-1-yl A.943 C 2
H_
5 2-(2'-chlorophenyl)eth-1-yl A.944 C 2
H
5 2-(3'-chlorophenyl)eth-1-yl A.945 CHr, 2-(4'-chlorophenyl)eth-1-yl A.946 C 2
H
5 ,5'-dichlorophenyl)eth-1-yl A.947~ C 2 H 2-2-ynpey~t-1-yl A.948 IC 2
H
5 2-(3'-cyanophenyl)eth-1-yl A.949 C 2
H
5 2-(4'-cyanophenyl)eth-1-yl A.949 C 2
H
5 2-(2'-methyphenyl)eth-1-yl A.950 C 2
H
5 2-(3'-methylphenyl)eth-1-yl A.952 C 2
H
5 2-(4'-methylphenyl)eth-1-yl A.953 C 2
H
5 2-(2'-methoyphenyl)eth-1-yl A.954 C 2
H
5 2-(3 '-methoxyphenyl)eth-1-yl A.954 C 2
H
5 2-(4'-methoxyphenyl)eth-1-yl A.955 C 2
H
5 2-(2 '-mtihoroeyphenyl)eth-1-yl A.957 C 2
H
5 2-(3 '-trifluoromethylphenyl)eth-1-yl A.957 C 2
H
5 2-(4 '-trifluoromethylphenyl)eth-1-yl A.958 C 2
H
5 3--enylo-1-yl heylet-1 A.959 C 2
H
5 3-(-orphenylprop-1-yl A.960 C 2
H
5 3-(2'-chlorophenyl)prop-1-yl A. 962 C 2
H
5 3- (4'-chiorophenyl )prop-1-yl A.962 C 2 HS 3-(2'-chlanophenyl)prop-1-yl A.964 C 2
H
5 3-(2'-cyanophenyl)prop-1-yl A.965 C 2
H
5 3-(4'-cyanophenyl)prop-1-yl A.966 C 2
H
5 3-(2 '-trifluoromethylphenyl)prop-1-yl A.967 C 2
H
5 4-phenylbut-1-yl A.968 C 2
H
5 4-(4'-chlorophenyl)but-1-yl A.969 C 2
H
5 6-(4'-chlorophenyl)hex-1-yl A.970 C 2 H5 2-pyridylmethyl A.971 C 2
H
5 3-pyridylmethyl A.972 IC 2
H
5 4-pyridylmethyl 0050/46043 137 No.R24 A. 973 C 2
H
5 4-chloropyridin-2-ylmethyl A. 974 C 2
H
5 5-chloropyridin-2-ylmethyl A. 975 C 2
H
5 6-chloropyridin-2-ylmethyl A. 976 C 2
H
5 5-chloropyridin-3-ylmethyl A. 977 C 2
H
5 6-chloropyridin-3-ylmethyl A. 978 C 2
H
5 2-chloropyridin-4-ylmethy.
A.979 C 2
H
5 2-pyrimidinylmethyl A. 980 C 2 HS 4-chloropyrimidin-2-ylmethyl A. 981 C 2
H
5 5-chloropyrimidin-2-ylmethyl A. 982 C 2
H
5 2-chloropyrimidin-4-ylmethyl A. 983 C 2
H
5 6-chloropyrimidin-4-ylmethyl A. 984 C 2
H
5 A.985 C 2
H
5 4-pyridazinylmethyl A.986 C 2
H
5 2-pyrazinylmethyl A. 987 C 2
H
5 5-chloropyrazin-2-ylmethyl A. 988 C 2
H
5 6-chloropyrazin-2-yliethyl A.989 C 2
H
5 3-pyridazinylmethyl A. 990 C 2
H
5 6-chloropyridazin-3-ylmethyl A.991 C 2
H
5 1,3,5-triazinylinethyl A.992 C 2
H
5 2-furylmethyl A.993 C 2
H
5 3-furylmethyl A.994 C 2
H
5 4-bromofur-2-ylmethyl A.995 C 2
H
5 5-chlorofur-2-.ylmethyl A.996 C 2
H
5 2-thienylmethyl A.997 C 2
H
5 3-thienylmethyl A. 998 C 2
H
5 5-methylthien-3-ylmethyl A. 999 CqHR 5-chlorothien-2-ylmethyl A. 1000 C 2
H
5 2-chlorothien-4-ylmethyl A.1001 C 2
H
5 2-pyrrolylmethyl A.1002 C 2
H
5 3-pyrrolylniethyl A.1003 C 2
H
5 2-oxazolylniethyl A. 1004 0 2
H
5 4-methyloxazol-2-ylmethyl A. 1005 CqH 5 5-methyloxazol-2-ylmethyl A. 1006 C 2
H
5 4-chloro-oxazol-2-ylmethyl A. 1007 C 2
H
5 5-chloro-oxazol-2-ylmethyl A.1008 CqHR 4-oxazolylmethyl A. 1009 C 2
H
5 2-methyloxazol-4-ylmethy.
A. 1010 C 2
H
5 5-methyloxazol-4-ylmethyl A. 1011 C 2
H
5 2-chloro-oxazol-4-ylmethyl 0050/46043 138 No.R24 A. 1012 C 2
H
5 5-chloro-oxazol-4-ylmethyl A.1013 C 2
H
5 A. 1014 C 2
H
5 A. 1015 C 2
H
5 A. 1016 IC9H 5 A. 1017 C 2
H
5 A.1018 C 2
H
5 2-thiazolylmethy.
A. 1019 C I 2
H
5 4-methylthiazol-2-ylmethyl A. 1020 C 2
H
5 5-methylthiazol-2-ylmethyl A. 1021 C 2
H
5 4-chlorothiazol-2-ylmethy.
A. 1022 C 2
H
5 5-chlorothiazol-2-ylmethyl A.1023 C 2
H
5 4-thiazolylmethyl A. 1024 C 2
H
5 12-methylthiazol-4-ylmethyl A%.1025 C 2 H 5-methyithiazol-4-ylmethyl A. 1026 C 2
H
5 2-chlorothiazol-4-ylmethyl A. 1027 C 2
H
5 5-chlorothiazol-4-ylmethyl A.1028 C 2
H
5 A. 1029 C 2
H
5 A. 1030 C 2
H
5 A. 1031 C 2
H
5 A. 1032 C 2
H
5 A.1033 C 2
H
5 3-isoxazolyilmethyl A. 1034 C 2
H
5 4-methylisoxazol-3-ylmethyl A. 1035 C 2
H
5 5-methylisoxazol-3-ylmethy.
A. 1036 C 2
H
5 4-chloro-isoxazol-3-ylmethyl A. 1037 C 2
H
5 5-chloro-isoxazol-3-ylmethy.
A.1038 C 2
H
5 4-isoxazolylmethyl A. 1039 C 2
H
5 3-methylisoxazol-4-ylmethyl A. 1040 C 2
H
5 5-methylisoxazol-4-ylmethy.
A. 1041 C 2
H
5 3-chloro-isoxazol-4-ylmethyl A. 1042 C 2
H
5 5-chloro-isoxazol-4-ylmethyl A.1043 C 2
H
5 A. 1044 IC7Hr A. 1045 C 2
H
5 A. 1046 C 2
H
5 A. 1047 C 2
H
5 A.1048 C 2
H
5 3-isothiazolylmethyl A. 1049 C 2
H
5 4-methyl-isothiazol-3-ylmethyl A. 1050 C 2
H
5 5-methyl-isothiazol-3-ylmethyl 0050/46043 139 No. R 2
R
A. 1051 C 2
H
5 4-chloro-isothiazol-3-ylmethyl A. 1052 C 2
H
5 5-chloro-isothiazol-3-ylmethyl A.1053 C 2
H
5 4-isothiazolylmethyl A. 1054 C 2
H
5 3-methyl-isothiazol-4-ylmethyl A. 1055 C 2
H
5 5-methyl-isothiazol-4-ylmethyl A. 1056 C, 2
H
5 3-chloro-isothiazol-4-ylmethyl A. 1057 C 2
H
5 5-chloro-isothiazol-4-ylmethyl A.1058 C 2
H
5 A. 1059 C 2
H
5 A. 1060 C 2
H
5 A. 1061 C 2
H
5 A. 1062 C 2
H
5 A.1063 jC 2
H
5 4-imidazolylmethyl A. 104t 2 n 5 1-phenylpyrazol-3-ylmethyl A. 1065 C 2
H
5 1-methylimidazol-4-ylmethyl A. 1066 C 2
H
5 i-phenyl-1,2 ,4-triazol-3-ylmethyl A. 1067 C 2
H
5 1,2, 4-oxadiazol-3-ylmethyl A. 1068 C 2
H
5 5-chloro-1,2 ,4-oxadiazol-3-ylmethyl A. 1069 C 2
H
5 5-methyl-1,2, 4-oxadiazol-3-ylmethyl A. 1070 C 2
H
5 5-trifluoromethyl-1,2,4-oxadiazol-3-yl- A. 1071 C 2
H
5 1,3, 4-oxadiazol-2-ylmethyl A. 1072 C 2
H
5 5-chloro-1,3, 4-oxadiazol-2-ylmethyl A. 1073 C 2
H
5 5-methyl-i, 3,4-oxadiazol-2-ylmethyl A. 1074 C 2
H
5 5-methoxy-1, 3, 4-oxadiazol-2-ylmethyl A. 1075 C 2
H
5 1,2, 4-thiadiazol-3-ylmethyl A. 1076 C 2
H
5 5-chloro-1,2 ,4-thiadiazol-3-ylmethyl A. 1077 C 2
H
5 5-methyl-1,2, 4-thiadiazol-3-ylmethyl A.1078 C 2
H
5 1,3,4-thiadiazol-2-ylmethyl A. 1079 C 2
H
5 5-chloro-1, 3,4-thiadiazol-2-ylmethyl A. 1080 C 2
H
5 5-methyl-i, 3,4-thiadiazol-2-ylmethyl A. 1081 C 2
H
5 5-cyano-1, 3,4-thiadiazol-2-ylmethyl A. 1082 C 2
H
5 2-(2 '-pyridinyloxy)eth-1-yl A. 1083 CAS 5 2-(3 '-pyridinyloxy)eth-1-yl A.1084 C 2
H
5 2-(4'-pyridinyloxy)eth-1-yl A. 1085 C 2
H
5 2-(2'-pyrimidinyloxy)eth-1-yl A.1086 C 2
H
5 2-(4 '-pyrimidinyloxy)eth-1-yl A.1087 C 2
H
5 2-(5'-pyrimidinyloxy)eth-1-yl A. 1088 C 2
H
5 2-(2 '-pyrazinyloxy)eth-1-yl 0050/46043 140 No.R24 A. 1089 C 2
H
5 2-(2'-pyridazinyloxy)eth-1-yl A. 1090 C 2
H
5 2-(3'-pyridazinyloxy)eth-1-yl A.1091 C 2
H
5 2 -(l',3',5'-triazinyloxy)eth-1-yl A.1092 C 2
H
5 2-(5'-methylisoxazol-3'-yloxy)eth-.1-yl A. 1093 CAS 5 2-(5 '-chloro-isoxazol-3 '-yloxy)eth-1-yl A.1094 C 2
H
5 2- -methoxythiazol-4 '-yloxy) eth- l-yl A. 1095 C 2
H
5 2-(4 '-chloro-oxazol-2 '-yloxy)eth-1-yl A.1096 C 2
H
5 2 -(l'-phenyl-'H-,',24'-trol.. 3'..yl ______oxy)eth-1-yl A.1097 C 2
H
5 2 -(1'-phenylpyrazol-3'-yloxy)eth-..yl A.1098 C 2
H
5
C
6
H
A.1099 C 2
H
5 2-Cl-C 6
H
4 A.100C 2
H
5 3-Cl-C 6
H
4 A.101C 2
H
5 14-Cl-C 6
H
4 A.1102 C 2
H
5 2,3-Cl 2
-C
6
H
3 A.1103' C 2
H
5 2 4-Cl 2
-C
6
H
3 A.1104 C 2
H
5 2,5-Cl 2
-C
6
H
3 A.1105 C 2
H
5 3,4-Cl 2
-C
6
H
3 A.1106 C 2
H
5 3,5-C1 2
-C
6
H
3 A.1107 C 2
H
5 4-CN-C 6
H
4 A.1108 C 2
H
5 2-N0 2
-C
6
H
4 A.1109 CAS 5 3-N0 2
-C
6
H
4 A.1110 C 2
H
5 4-N0 2
-C
6
H
4 A.1111 CqHs 2,4-(N0 2 2
-C
6
H
3 A.1112 C 2
H
5 2-CH 3
-C
6
H
4 A.1113 CAS 5 3-CH 3
-C
6
H
4 A.1114 C7Hq 4-CH 3
-C
6
H
4 A.1115 C 2
H
5 2,3-(CH 3 2
-C
6
H
3 A.1116 C 2
H
5 2,4-(CH 3 2
-C
6
H
3 A.1117 CAS 5 2,5-(CH 3 2
-C
6
H
3 A.1118 C 2
H
5 2,6-(CH 3 2
-C
6
H
3 A.1119 C 2
H
5 2-C 6
H
5
-C
6
H
4 A.1120 jC 2
H
5 3-C 6
H
5
-C
6
H
4 A.1121 C 2
H
5 4-C 6
H
5
-C
6
H
4 A.1122 CAH 5 3-OCH 3
-C
6
H
4 A.1123 C 2
H
5 4-OCH 3
-C
6
H
4 A.1124 C 2
H
5 3-acetyl-C 6
H
4 A.1125 C 2
H
5 4-acetyl-C 6
H
4 A. 1126 C 2
H
5 13-methoxycarbonyl-C 6
H
4 0050/46043 141 No.R24 A. 1127 C 2
H
5 4-methoxycarbonyl-C 6
H
4 A.1128 C 2
H
5 3-CF 3
-C
6
H
4 A.1129 C 2
H
5 4-CF 3
-C
6
H
4 A-1130 C 2
H
5 2-naphthyl A. 1131 C 2
H
5 6-chloropyridazin-3-yl A.1132 C 2
H
5 5-chloropyrazin-2-yl A.1133 C 2
H
5 quinolin-2-yl A. 1134 JC 2
H
5 2, 5-dimethylpyrazin-3-yl A.1135 C 2
H
5 pyrazin-2-yl A.1136 C 2
H
5 3-chloropyrid-2-yl A.1137 0 2
H
5 6-chloropyrid-2-yl A.1138 C 2
H
5 4-trifluoromethyl, 6-chloropyrid-2-yl A. 1139 C 2
H
5 4-trifluoromethylpyrid-2-yl A.1140_ C2 H5 60- rifluoromethylpyrid-2-yl A.1141 C 2
H
5 6-methoxypyrid -2-yl A.1142 C 2
H
5 5-chloropyrid-2-yl A.1143 C 2
H
5 pyrid-2-yl A.1144 C 2
H
5 benzothiazol-2-yl A.1145 C 2
H
5 7-chloroquinolin-4-yl A.1146 C 2 HS 3-nitropyrid-2-yl A.1147 C 2
H
5 pyrrol-3-yl A.1148 C 2
H
5 pyrrol-2-yl A.1149 C 2
H
5 2,6-dioctylpyrid-4-yl A.1150 C 2
H
5 5-nitropyrid-2-yl A.1151 C 2
H
5 pyrid-4-yl A.1152 C 2
H
5 pyrid-3-yl A.1153 C 2
H
5 pyrimidin-2-yl A.1154 C 2
H
5 pyrimidin-4-yl A.1155 C 2
H
5 quinazolin-4-yl A. 1156 C 2
H_
5 6-chloropyrimidin-4-yl A. 1157 C 2
H
5 6-methoxypyrimidin-4-yl A. 1158 C 2
H
5 2,5, 6-trichloropyrimidin-4-yl A. 1159 IC 2
H
5 2, 6-dimethylpyrimidin-4-yl A.1160 C 2
H
5 2-methyl, 6-chloropyrimidin-4-yl A. 1161 C 2
H
5 2-methyl, 6-ethoxypyrimidin-4-yl A. 1162 C 2
H
5 4,5, 6-trichloropyrimidin-2-yl A. 1163 C 2
H
5 4, 6-dimethoxypyrimidin-2-yl A. 1164 C 2
H
5 4, 6-dimethylpyrimidin-2-yl A. 1165 C 2
H
5 4, 6-dichloropyrimidin-2-yl 0050/46043 142 No. R 2
R
A. 1166 C 2
H
5 4-methyl, 6-methoxypyrimidin-2-yl A.1167 C 2
H
5 4-chioro, 6-methoxypyrimidin-2-yl A. 1168 C 2
H
5 6-chloroquinoxalin-2-yl A.1169 C 2
H
5 3,6-dichloro-1,2,4-triazin-5-yl A.1170 C 2
H
5 4-methoxy-1,3,5-triazin-2-y.
A. 1171 C 2
H
5 4-ethoxy-1, 3, 5-triazin-2-yl A.1172 C 2
H
5 4,6-dichloro-1,3,5-triazin-2-yl A.1173 C 2
H
5 4-ethoxy, 6-chloro-1,3,5-triazin-2-yl A.1174 CAS 5 isoxazol-3-yl A.1175 C 2
H
5 thien-2-yl A.1176 C 2
H
5 fur-2-yl A.1177 C 2
H
5 A. 1178 C 2
H
5 i(E)-1-chloropropen-3-yl A. 117 9 C 2
H
5 q (It)-4-(4-chlorop'eny)but-2-en-1-yl A.1180 C 2
H
5 propyn-3-yl A.1181 C 2
H
5 methylcarbonyl A.1182 C 2
H
5 ethylcarbonyl A.1183 C 2
H
5 n-propylcarbonyl A.1184 C 2
H
5 i-propylcarbonyl A.1185 C 2
H
5 n-butylcarbonyl A.1186 C 2
H
5 s-butylcarbonyl A.1187 C 2
H
5 i-butylcarbonyl A.1188 C 2
H
5 t-butylcarbonyl A.1189 C 2
H
5 n-pentylcarbonyl A.1190 CqHq i-pentylcarbonyl A.1191 C 2
H
5 neo-pentylcarbonyl A.1192 C 2
H
5 n-hexylcarbonyl A.1193 C 2
H
5 n-octylcarbonyl A.1194 C 2
H
5 1-propenylcarbonyl A. 1195 C 2
H
5 2-penten-1-yl-carbonyl A. 1196 C 2
H
5 2, 5-heptadien-1-yl-carbonyl A.1197 C 2
H
5 benzoyl A.1198 C 2
H
5 2-chlorobenzoyl A.1199 C 2
H
5 3-chlorobenzoyl A.1200 C 2
H
5 4-chlorobenzoyl A.1201 C 2
H
5 2-cyanobenzoyl A.1202 C 2
H
5 3-cyanobenzoyl A.1203 C 2
H
5 4-cyanobenzoy.
A.1204 C 2
H
5 4-methoxybenzoyl 0050/46043 143 No.R24 A. 1205 C 2
H
5 2-pyridylcarbonyl A.1206 C 2
H
5 3-pyridylcarbonyl A.1207 C 2
H
5 4-pyridylcarbonyl A.1208 C 2
H
5 2-pyrimidinylcarbony.
A.1209 C 2
H
5 2-oxazolylcarbonyl A. 1210 C 2
H
5 4 A.1211 C 2
H
5 methylsulfony.
A.1212 C 2
H
5 ethylsulfony.
A.1213 C 2
H
5 n-propylsulfonyl A.1214 C 2
H
5 i-propylsulfonyl A.1215 ICqHq n-butylsulfonyl A.1216 C 2
H
5 t-butylsulfonyl A.1217 C 2
H
5 n-pentylsulfonyl A. 121 C 2 5 neo-pentyis-Uif-n yI A.1219 C 2
H
5 n-hexylsulfonyl A.1220 C 2
H
5 n-octylsulfonyl A.1221 C 2
H
5 phenylsulfonyl A. 1222 C 2
H
5 2-chlorophenylsulfonyl A. 1223 C 2
H
5 3-chlorophenylsulfonyl A. 1224 C 2
H
5 4-chiorophenylsulfonyl A.1225 C 2
H
5 2-cyanophenylsulfony.
A.1226 C 2
H
5 3-cyanophenylsulfonyl A.1227 C 2
H
5 4-cyanophenylsulfonyl A.1228 C 2
H
5 2-pyridylsulfonyl A.1229 C 2
H
5 3-pyridylsulfonyl A.1230 C 2
H
5 4-pyridylsulfonyl A.1231 C 2
H
5 2-pyrimidinylsulfonyl A.1232 C 2
H
5 4-oxazolylsulfonyl A. 1233 CAS 5 5-chlorothiazol-2ylsulfonyl [sic]I A. 1234 C 2
H
5 2-t-C 4 H9-C 6
H
4
-CH
2 A.1235 C 2
H
5 3-t-C 4
H
9
-C
6
H
4
-CH
2 A.1236 C 2
H
5 4-t-C 4
H
9
-C
6
H
4
-CH
2 A. 1237 C 2
H
5 2-(4 '-chlorothiazol-2 '-yloxy)eth-1-yl A.1238 C 2
H
5 1'-methylpyrazol-4 '-yloxy)eth-1-yl A.1239 C 2
H
5 4-Br-C 6
H
4 A.1240 CAS 5 3,5-(CH 3 2
-C
6
H
3 A.1241 C 2
H
5 4-C 2
H
5
-C
6
H
4 A. 1242 C 2
H
5 3-dimethylaminocarbonyl-C 6
H
4 A. 1243 IC 2
H
5 4-dimethylaminocarbonyl-C 6
H
4 0050/46043 144 No.R24 A.1244 C 2
H
5 2-hydroxyprop-1-yl A. 1245 0 2
H
5 6-hydroxy-2-methylpyrimidin-4-ylmethyl A.1246 jC 2
H
5 f6-OH,2-CH(CH 3 2 -pyrimidin-4-ylI-CH 2 A.1247 C 2
H
5 [6-OH,2-CH(CH 2 2 -pyrimidin-4-yl]-CH 2 A.1248 C 2
H
5 5-(2'-furan)-pent-1-yl A. 1249 C 2
H
5 5-(2 '-N-methylpyrrol)-pent-1-yl A.1250 C 2
H
5 [2-(4-C1-C 6
H
4 )-oxazol-4-yl1-CH 2 A.1251 C 2
H
5 3-CF 3 -pyridin-2-yl A.1252 C 2
H
5 5-CF 3 -pyridin-2-yl A.1253 C 2
H
5 6-(2'-thienyl)hex-1-yl A. 1254 C 2
H
5 (E)-3-chlorobut-2-en-1-yl A. 1255 C 2
H
5 (Z )-3-chlorobut-2-en-1-yl A. 1256 C 2
H
5 (E)-2-bromobut-2-en-1-yl A. 1257 C 2
H
5 (Z )-2-bromobut-2-en-i-yi A. 1258 C 2
H
5 (E)-l-chloroprop-l-en-3-yl A. 1259 C 2
H
5 (Z )-1-chloroprop-1-en-3-yl A.1260 C 2
H
5 But-l-en-3-yl A.1261 C 2
H
5
CH
2
CH
2 Br A. 1262 C 2
H
5
CH
2
CH
2
CH
2 Br A.1263 C 2
H
5
CH
2
CH
2
CH
2
CH
2 Br A.1264 C 2
H
5 2-methoxyprop-1-yl A.1265 C 2
H
5 2-ethoxyprop-1-yl A.1266 CAT 5 2-isopropoxyprop-1-yl A-1267 CHq but-1-yn-3-yl A.1268, C 2
H
5 but-1-yn-4-yl A.1269 C 2
H
5 but-2-yn-4-yl A.1270 CqH,; pent-1-yn-4-yl A.1271 C 2
H
5 pent-2-yn-4-yl A.1272 C 2
H
5 A.1273 C 2
H
5 A. 1274 C 2
H
5 E-2-chlorobut-2-en-1-yl A. 1275 C 2
H
5 Z-2-chlorobut-2-en-1-yl A. 1276 C 2
H
5 9 Z-1-chloroprop-1-en-3-yl A. 1277 C 2
H
5 2-methylprop-1-en-3-yl A. 1278 C 2
H
5 2-chloroprop-1-en-3-yl A.1279 C 2
H
5 2-bromoprop-1-en-3-yl A.1280 C 2
H
5 but-2-en-1-yl A.1281 C 2
H
5 but-3-en-1-yl A.1282 C 2
H
5 1-iodoprop-1-yn-3-yl 0050/46043 145 No.R24 A. 1283 C 2
H
5 E-3-bromobut-2-en-1-yl A. 1284 C 2
H
5 Z-3-bromobut--2-en-1-yl A.1285 i-C 3
H
7
H
A.1286 i-C 3
H
7 CH 3 A.1287 i-C 3
H
7 C 2
H
A.1288 i-C 3
H
7 n-C 3
H
7 A.1289 i-C 3
H
7 i-C 3
H
7 A.1290 i-C 3
H
7 cyclopropyl A.1291 i-C 3
H
7 n-C 4
H
9 A.1292 i-C 3
H
7
S-C
4
H
9 A.1293 i-C 3
H
7 i-C 4
H
9 A.1294 i-C 3
H
7 t-C 4
H
9 A.1295 i-C 3
H
7 n-C 5 Hll A.1296 i-CU 3
H
7 i-C 5 Hll A.1297 i-C 3
H
7 neo-C 5 Hl 1 A.1298 i-C 3
H
7 cyclopentyl A.1299 i-C 3
H
7 n-C 6 Hl 3 A.1300 i-C 3
H
7 cyclohexy.
A.1301 i-C 3
H
7 n-C 8 Hl 7 A.1302 i-C 3
H
7 CH 2
CH
2 Cl A.1303 i-C 3
H
7 (CH 2 4 Cl A.1304 i-C 3
H
7
CH
2
CN
A.1305 i-C 3
H
7 C2HC A.1306 i-C 3
H
7
(H)C
A.1307 i-C 3
H
7
(H)C
A.1308 i-C 3
H
7
(H)C
A.1309 i-C 3
H
7 cyclohexylmethy.
A. 1310 i-C 3
H
7 2-cyclohexyleth-1-yl A.1311 i-C 3
H
7 cyclopropylmethyl A. 1312 i-C 3
H
7 2-cyclopropyleth-1-yl A.1313 i-C 3
H
7 2-methoxyeth-1-yl A.1314 i-C 3
H
7 2-ethoxyeth-1-yl A. 1315 i-C 3
H
7 2-isopropoxyeth-1-yl A.1316 i-C 3
H
7 3-methoxyprop-1-yl A.1317 i-C 3
H
7 3-ethoxyprop-1-yl A. 1318 i-C 3
H
7 3-isopropoxyprop-1-yl A.1319 i-C 3
H
7 4-methoxybut-1-yl A. 1320 i-C 3
H
7 4-isopropoxybut-1-yl A.1321 i-C 3
H
7 propen-3-yl Fl 4 7- ov 0050/46043 146 No.R24 A.1322 i-C 3
H
7 but-2-en-1-yl A. 1323 i-C 3
H
7 3-methylbut-2--en-1-yl A.1324 i-C 3
H
7 2-vinyloxyeth-1-yl A.1325 i-C 3
H
7 allyloxyeth-l-yl A. 1326 i-C 3
H
7 2-trifluoromethoxyeth-1-yl A. 1327 i-C 3
H
7 3-trifluoromethoxyprop-1-yl A. 1328 i-C 3
H
7 4-difluoromethoxybut-1-yl A. 1329 ji-C 3
H
7 hydroxycarboriylmethyl A. 1330 i-C 3
H
7 methoxycarbonylmethyl A.1331 i-C 3
H
7 aminocarbonylmethyl A. 1332 i-C 3
H
7 N-methylaminocarbonylmethyl A. 1333 i-C 3
H
7 N,N-dimethylaminocarbonyl-methyl A. 1334 i-C 3
H
7 2-hydroxycarbonyleth-1-yl .1335 i-C H 7 2-methoxycarbonyleth-1-yl A. 1336 i-C 3
H
7 2-aminocarbonyleth-1-yl A. 1337 i-C 3
H
7 2-N-methylaminocarbonyleth-1-yl A. 1338 i-C 3
H
7 2-dimethylaminocarbonyleth-1.yl A.1339 i-C 3
H
7 2-aminoeth-1-yl A.1340 i-C 3
H
7 2-aminoprop-1-yl A.1341 i-C 3
H
7 4-aminobut-1-yl A. 1342 i-C 3
H
7 3-dimethylaminoprop-1-yl A. 1343 i-C 3
H
7 4-aminothiocarbonylbut-1-yl A.1344 i-C 3
H
7 2-oxopropyl A.1345 i-C 3
H
7 cyclohexyl A.1346 i-C 3
H
7 cyclopropyl A.1347 i-C 3
H
7 cyclopentyl A. 1348 i-C 3
H
7 2-methoxyiminoprop-1-yl A. 1349 i-C 3
H
7 2-methoxyiminoeth-1-yl A. 1350 i-C 3
H
7 6-aminocarbonylhex-1-yl A. 1351 ji-C 3
H
7 3-aminothiocarbonylprop-1-yl A. 1352 i-C 3
H
7 2-aminothiocarbonyleth-1-yl A. 1353 i-C 3
H
7 aminothiocarbonylmethyl A.1354 i-C 3
H
7 4-(N,N-dimethylamino)but-1-yl A.1355 i-C 3
H
7 2-(methylthio)eth-1-yl A. 1356 i-C 3
H
7 2-(methylsulfonyl)eth-1-yl A.1357 i-C 3
H
7 4-(methylthio)prop-1-yl A. 1358 i-C 3
H
7 4-(methylsulfonyl)prop-1-y.
A.1359 i-C 3
H
7 benyzi A. 1360 i-0 3
H
7 2-F-C 6
H
4
-CH
2 0050/46043 147 No. R 2
R
A. 1361 i-C 3
H
7 3-F-C 6
H
4
-CH
2 A.1362 i-C 3
H
7 4-F-C 6
H
4
-CH
2 A.1363 i-C 3
H
7 2,3-F 2
-C
6
H
3
-CH
2 A.1364 i-C 3
H
7 2,4-F 2
-C
6
H
3
-CH
2 A.1365 i-C 3
H
7 2,5-F 2
-C
6
H
3
-CH
2 A.1366 i-C 3
H
7 2,6-F 2
-C
6
H
3
-CH
2 A.1367 i-C 3
H
7 3,4-F 2
-C
6
H
3
-CH
2 A.1368 i-C 3
H
7 3,5-F 2
-C
6
H
3
-CH
2 A.1.369 i-C 3
H
7 2-Cl-C 6
H
4
-CH
2 A.1370 i-C 3
H
7 3-C1-C 6
H
4
-CH
2 A.1371 i-C 3
H
7 4-Cl-C 6
H
4
-CH
2 A.1372 i-C 3
H
7 2,3-C1 2
-C
6
H
3
-CH
2 A.1373 i-C 3
H
7 2,4-C 2
-C
6
H
3
-CH
2 I A -C 3
H
7 C26H 2,5-C CH-CH 2 A.1375 ji-C 3
H
7 2,6-Cl 2
-C
6
H
3
-CH
2 A.1376 i-C 3
H
7 3,4-C 2
-C
6
H
3
-CH
2 A.1377 i-C 3
H
7 3,5-C 2
-C
6
H
3
-CH
2 A.1378 i-C 3
H
7 2,3,4-C 3
-C
6
H
2
-CH
2 A.1379 i-C 3
H
7 2,3,5-C 3
-C
6
H
2
-CH
2 A.1380 i-C 3
H
7 2,3,6-C 3
-C
6
H
2
-CH
2 A.1381 i-C 3
H
7 2,4,5-C 3
-C
6
H
2
-CH
2 A.1382 i-C 3
H
7 2,4,6-C 3
-C
6
H
2
-CH
2 A. 1383 i-C 3
H
7 3, 4, 5-Cl 3
-C
6
H
2
-CH
2 A.1384 i-C 3
H
7 2-Br-C 6
H
4
-CH
2 A.1385 i-C 3
H
7 3-Br-C 6
H
4
-CH
2 A.1386 i-C 3
H
7 4-Br-C 6
H
4
-CH
2 A.1387 i-C 3
H
7 2,3-Br 2
-C
6
H
3
-CH
2 A.1388 i-C 3
H
7 2,4-Br 2
-C
6
H
3
-CH
2 A.1389 i-C 3
H
7 2,5-Br 2
-C
6
H
3
-CH
2 A.1390 i-C 3
H
7 2,6-Br 2
-C
6
H
3
-CH
2 A.1391 i-C 3
H
7 3,4-Br 2
-C
6
H
3
-CH
2 A.1392 i-C 3
H
7 3,5-Br 2
-C
6
H
3
-CH
2 A.1393 i-C 3
H
7 2-F, 3-C-C 6
H
3
-CH
2 A.1394 i-C 3
H
7 2-F, 4-C1-C 6
H
3
-CH
2 A. 1395 i-C 3
H
7 2-F, 5-C1-C 6
H
3
-CH
2 A.1396 i-0 3
H
7 2-F, 3-Br-C 6
H
3
-CH
2 A. 1397 i-C 3
H
7 2-F, 4-Br-C 6
H
3
-CH
2 A.1398 i-C 3
H
7 2-F, 5-Br-C 6
H
3
-CH
2 A. 399i-C 3
H
7 12-Cl, 3-Br-C 6
H
3
-CH
2 0050/46043 148 No.R24 A. 1400 i-C 3
H
7 2-Cl, 4-Br-C 6
H
3
-CH
2 A.1401 i-C 3
H
7 2-Cl, 5-Br-C 6
H
3
-CH
2 A. 1402 i-C 3
H
7 3-F, 4-Cl-C 6
H
3
-CH
2 A. 1403 i-C 3
H
7 3-F, 5-Cl-C 6
H
3
-CH
2 A.1404 i-C 3
H
7 3-F, 6-Cl-C 6
H
3
-CH
2 A.1405 i-C 3
H
7 3-F, 4-Br-C 6
H
3
-CH
2 A.1406 i-C 3
H
7 3-F, 5-Br-C 6
H
3
-CH
2 A.1407 i-C 3
H
7 3-F, 6-Br-C 6
H
3
-CH
2 A.1408 i-C 3
H
7 3-Cl, 4-Br-C 6
H
3
-CH
2 A.1409 i-C 3
H
7 3-Cl, 5-Br-C 6
H
3
-CH
2 A. 1410 i-C 3
H
7 3-Cl, 6-Br-C 6
H
3
-CH
2 A. 1411 i-C 3
H
7 4-F, 5-Cl-C 6
H
3
-CH
2 A.1412 i-C 3
H
7 4-F, 6-Cl-C 6
H
3
-CH
2 r;1. 1 4 3D^ 7 A.1414.. I- i- 3 n 7 4-F, 6-Br-C 6
H
3
-CH
2 A.1414 i-C 3
H
7 4-C, -Br-C 6
H
3
-CH
2 A.1415 i-C 3
H
7 5-F, 6-l-C 6
H
3
-CH
2 A. 1417 i-C 3
H
7 5-F, 6-Br-C 6
H
3
-CH
2 A.1417 i-C 3
H
7 5-C, 6-Br-C 6
H
3
-CH
2 A.1418 i-C 3
H
7 3-r5-Cl, 5-Br-C 6
H-CH
2 A.1419 i-C 3
H
7 2-BN-C 6 4
-CH
2 A. 1421 li-C 3
H
7 3-CN-C 6
H
4
-CH
2 A. 1422 i-C 3
H
7 3-CN-C 6
H
4
-CH
2 A.1422 i-C 3
H
7 2-N-C 6
H
4
-CH
2 A.1423 i-C 3
H
7 3-N0 2
-C
6
H
4
-CH
2 A. 1425 i-C 3
H
7 4-N0 2
-C
6
H
4
-CH
2 A.1425 i-C 3
H
7 2-CH 3
-C
6
H
4
-CH
2 A.1426 i-C 3
H
7 3-CH 3
-C
6
H
4
-CH
2 A. 1428 i-C 3
H
7 4-CH 3
-C
6
H
4
-CH
2 A.1428 i-C 3
H
7 2,-CH 3 C6H-CH2- A.1429 i-C 3
H
7 2,4-(CH 3 2
-C
6
H
3
-CH
2 A.1430 i-C 3
H
7 2,4-(CH 3 2
-C
6
H
3
-CH
2 A.1431 i-C 3
H
7 2,6-(CH 3 2
-C
6
H
3
-CH
2 A.1432 i-C 3
H
7 3,4-(CH 3 2
-C
6
H
3
-CH
2 A.1433 i-C 3
H
7 3,5-(CH 3 2
-C
6
H
3
-CH
2 A.1434 i-C 3
H
7 2-C 25 -C3C 6 H3-CH 2 A.1435 i-C 3
H
7 3-C 2
H
5
-C
6
H
4
-CH
2 A.1436 i-C 3
H
7 3-C 2
H
5
-C
6
H
4
-CH
2 A.1438 i-C 3
H
7 12-i-C 3
H
7
-C
6
H
4
-CH
2 71 N.
0050/46043 149 No.R24 A. 1439 i-C 3
H
7 3-i-C 3
H
7
-C
6
H
4
-CH
2 A.1440 i-C 3
H
7 4-i-C 3
H
7
-C
6
H
4
-CH
2 A. 1441 i-C 3
H
7 2-cyclohexyl-C 6
H
4
-CH
2 A. 1442 i-C 3
H
7 3-cyclohexyl-C 6
H
4
-CH
2 A. 1443 i-C 3
H
7 4-cyclohexyl-C 6
H
4
-CH
2 A. 1444 ji-C 3
H
7 2-vinyl-C 6
H
4
-CH
2 A. 1445 i-C 3
H
7 3-vinyl-C 6
H
4
-CH
2 A. 1446 i-C 3
H
7 4-vinyl-C 6
H
4
-CH
2 A-1447 i-C 3
H
7 2-allYl-C 6
H
4
-CH
2 A.1448 i-C 3
H
7 3-allYl-C 6
H
4
-CH
2 A.1449 i-C 3
H
7 4-allYl-C 6
H
4
-CH
2 A.1450 i-C 3
H
7 2-C 6
H
5
-C
6
H
4
-CH
2 A.1451 i-C 3
H
7 3-C 6
H
5
-C
6
H
4
-CH
2 A.1452 i-C 3
H
7 4-C 6
H
5
-C
6
H
4
-CH
2 A.1453 i-C 3
H
7 3-CH 3 5-t-C 4 H9-C 6
H
3
-CH
2 A.1454 i-C 3
H
7 2-QH-C 6
H
4
-CH
2 A.1455 i-C 3
H
7 3-OH-C 6
H
4
-CH
2 A. 1456 i-C 3
H
7 4-OH-C 6
H
4
-CH
2 A. 1457 i-C 3
H
7 2-OCH 3
-C
6
H
4
-CH
2 A. 1458 i-C 3
H
7 3-OCH 3
-C
6
H
4
-CH
2 A.1459 i-C 3
H
7 4-OCH 3
-C
6
H
4
-CH
2 A.1460 i-C 3
H
7 2,3-(OCH 3 2
-C
6
H
3
-CH
2 A.1461 i-C 3
H
7 2,4-(OCH 3 2
-C
6
H
3
-CH
2 A.1462 i-C 3
H
7 2,5-(OCH 3 2
-C
6
H
3
-CH
2 A.1463 i-C 3
H
7 3,4-(OCH 3 2
-C
6
H
3
-CH
2 A.1464 i-C 3
H
7 3,5-(OCH 3 2
-C
6
H
3
-CH
2 A.1465 i-C 3
H
7 3,4,5-(OCH 3 3
-C
6
H
2
-CH
2 A.1466 i-C 3
H
7 2-0C 2
H
5
-C
6
H
4
-CH
2 A.1467 i-C 3
H
7 3-0C 2
H
5
-C
6
H
4
-CH
2 A.1468 i-C 3
H
7 4-0C 2
H
5
-C
6
H
4
-CH
2 A. 1469 i-C 3
H
7 2-0- (n-C 3
H
7
)-C
6
H
4
-CH
2 A. 1470 i-C 3
H
7 3-0- (n-C 3
H
7
)-C
6
H
4
-CH
2 A. 1471 i-C 3
H
7 4-0- n-C 3
H
7
-C
6
H
4
-CH
2 A. 1472 i-C 3
H
7 2-0- (i-C 3
H
7
)-C
6
H
4
-CH
2 A. 1473 i-C 3
H
7 3-0- (i-C 3
H
7
)-C
6
H
4
-CH
2 A. 1474 i-C 3
H
7 4-0- (i-C 3
H
7
)-C
6
H
4
-CH
2 A. 1475 i-C 3
H
7 4-0- (n-C 4
H
9
)-C
6
H
4
-CH
2 A. 1476 i-C 3
H
7 I3-0- (t-C 4
H
9
)-C
6
H
4
-CH
2 A.1477 i-C 3
H
7 1 4-0- (n-C 6 Hl 3
-C
6
H
4
-CH
2 0050/46043 150 No.R24 A.1478 i-C 3
H
7 2-O-allYl-C 6
H
4
-CH
2 A. 1479 i-C 3
H
7 3-O-allYl-C 6
H
4
-CH
2 A. 1480 i-C 3
H
7 4-O-allYl-C 6
H
4
-CH
2 A.1481 i-C 3
H
7 2-CF 3
-C
6
H
4
-CH
2 A.1482 i-C 3
H
7 3-CF 3
-C
6
H
4
-CH
2 A. 1483 i-C 3
H
7 4-CF 3
-C
6
H
4
-CH
2 A.1484 i-C 3
H
7 2-acetyl-C 6
H
4
-CH
2 A.1485 i-C 3
H
7 3-acetyl-C 6
H
4
-CH
2 A. 1486 i-C 3
H
7 4-acetyl-C 6
H
4
-CH
2 A. 1487 i-C 3
H
7 2-methoxycarbonyl-C 6
H
4
-CH
2 A. 1488 i-C 3
H
7 3-methoxycarbonyl-C 6
H
4
-CH
2 A. 1489 i-C 3
H
7 4-methoxycarbonyl-C 6
H
4
-CH
2 A. 1490 i-C 3
H
7 2-aminocarbonyl-C 6
H
4
-CH
2 A. 1491 i-C 3
H
7 3-aminocarbonyl-C 6
H
4
-CH
2 A. 1492 i-C 3
H
7 4 -aminocarbonyl-C 6
H
4
-CH
2 A. 1493 i-C 3
H
7 2 -dimethylaminocarbonyl-C 6
H
4
-CH
2 A. 1494 i-C 3
H
7 3-dimethylaminocarbonyl-C 6
H
4
-CH
2 A. 1495 i-C 3
H
7 4-dimethylaminocarbonyl-C 6
H
4
-CH
2 A. 1496 i-C 3
H
7 2- (N'-methylaminocarbonyl)
-C
6
H
4
-CH
2 A. 1497 i-C 3
H
7 3-(N-methylaxninocarbonyl)-C 6
H
4
-CH
2 A. 1498 i-C 3
H
7 4- (N-methylaminocarbonyl
-C
6 H4-CH 2 A.1499 i-C 3
H
7 2-H 2
N-C
6
H
4
-CH
2 A. 1500 i-C 3
H
7 3-H 2
N-C
6
H
4
-CH
2 A.1501 i-C 3
H
7 4-H 2 N-0 6
H
4
-CH
2 A. 1502 i-C 3
H
7 2-aminothiocarbonyl-C 6
H
4
-CH
2 A. 1503 i-C 3
H
7 3-aminothiocarbonyl-C 6
H
4
-CH
2 A. 1504 i-C 3
H
7 4-aminothiocarbonyl-C 6
H
4
-CH
2 A. 1505 i-C 3
H
7 2-methoxyiminomethyl-C 6
H
4
-CH
2 A. 1506 i-0 3
H
7 3-methoxyiminomethyl-C 6
H
4
-CH
2 A. 1507 i-C 3
H
7 4-methoxyiminomethyl-C 6
H
4
-CH
2 A.1508 i-C 3
H
7 2-formyl-0 6
H
4
-CH
2 A.1509 i-C 3
H
7 3-formyl-C 6
H
4
-CH
2 A.1510 i-C 3
H
7 4-formyl-C 6
H
4
-CH
2 A. 1511 i-C 3
H
7 1'-methoxyiminoeth-1 '-yl)-C 6
H
4
-CH
2 A. 1512 i-C 3
H
7 3-(1 1 '-methoxyiminoeth-1
-C
6
H
4
-CH
2 A. 1513 i-C 3
H
7 1'-methoxyiminoeth-1 '-Yl)-C 6
H
4
-CH
2 A.1514 i-C 3
H
7 2-SCH 3
-C
6
H
4
-CH
2 A. 1515 i-C 3
H
7 3-SCH 3
-C
6
H
4
-CH
2 A.1516 i-0 3
H
7 4-SCH 3
-C
6
H
4
-CH
2 ~A2~ ~r'vrc~ 0050/46043 151 No. R 2
R
A. 1517 i-C 3
H
7 2-SO 2
CH
3
-C
6
H
4
-CH
2 A.1518 i-C 3
H
7 3-SO 2
CH
3
-C
6
H
4
-CH
2 A.1519 i-C 3
H
7 4-SO 2
CH
3
-C
6
H
4
-CH
2 A.1520 i-C 3
H
7 2-OCF 3
-C
6
H
4
-CH
2 A. 1521 i-C 3
H
7 3-OCF 3
-C
6
H
4
-CH
2 A.1522 i-C 3
H
7 4-OCF 3
-C
6
H
4
-CH
2 A.1523 i-C 3
H
7 2-OCHF 2
-C
6
H
4
-CH
2 A.1524 i-C 3
H
7 3-OCHF 2
-C
6
H
4
-CH
2 A.1525 i-C 3
H
7 4-OCHF 2
-C
6
H
4 -d11 2 A. 1526 i-C 3
H
7 3-CF 3 4-OCF 3
-C
6
H
3
-CH
2 A.1527 i-C 3
H
7 1-naphthyl-CH 2 A.1528 i-C 3
H
7 2-naphthyl-CH 2 A.129i-C 3
H
7 2-phenoxyeth-1-yl A.1)50 l-C 3
H
7 2-(2'-chiorophenoxy)eth-1-yl A.1531 i-C 3
H
7 2-(3 '-chlorophenoxy)eth-1-yl A.1532 i-C 3
H
7 2-(4 '-chlorophenoxy)eth-1-yl A. 1533 i-C 3
H
7 ,5 '-dichlorophenoxy)eth-1-yl A.1534 i-C 3
H
7 2-(2'-cyanophenoxy)eth-1-yl A. 1535 i-C 3
H
7 2-(3 '-cyanophenoxy)eth-1-yl A. 1536 i-C 3
H
7 2-(4 '-cyanophenoxy)eth-1-yl A.1537 i-C 3
H
7 2-(2 '-methylphenoxy)eth-1-yl A. 1538 i-C 3
H
7 2-(3 '-methylpherioxy)eth-1-yl A.1539 i-C 3
H
7 2-(4 '-methylphenoxy)eth-1-yl A. 1540 i-C 3
H
7 2-(3 '-t-butylphenoxy)eth-1-yl A. 1541 i-C 3
H
7 '-t-butylphenoxy)eth-1-yl A.1542 i-C 3
H
7 2-(2'-nitrophenoxy)eth-1-yl A.1543 i-C 3
H
7 2-(3'-nitrophenoxy)eth-1-yl A. 1544 i-C 3
H
7 2-(4 '-nitrophenoxy)eth-1-yl A. 1545 i-C 3
H
7 2-(2 '-methoxyphenoxy)eth-1-yl A.1546 i-C 3
H
7 -methoxyphenoxy)eth-1-yl A. 1547 i-C 3
H
7 2-(4 '-methoxyphenoxy)eth-1-yl A. 1548 i-C 3
H
7 2-(2 '-trifluoromethylphenoxy)eth-1-yl A. 1549 i-C 3
H
7 2-(3 '-trifluoromethylphenoxy)eth-1-yl A. 1550 i-C 3
H
7 2-(4 '-trifluoromethylphenoxy)eth-1-yl A.1551 i-C 3
H
7 2-(2'-acetylphenoxy)eth-1-yl A. 1552 i-C 3
H
7 2-(3 '-acetylphenoxy)eth-1-yl A.1553 i-C 3
H
7 2-(4'-acetylphenoxy)eth-1-y.
A. 1554 i-C 3
H
7 2-(2 '-methoxycarbonyl)eth-1-yl 4. 1555 ji-C 3
H
7 2-(3 '-methoxycarbonyl)eth-1-yl 0050/46043 152 No.R24 A. 1556 i-C 3
H
7 2-(4 '-methoxycarbonyl)eth-1-yl A. 1557 i-C 3
H
7 2-(2 '-dimethylaminocarbonyl)eth-1-.yl A. 1558 i-C 3
H
7 2-(3 '-dimethylaminocarbonyl)eth-1-yl A. 1559 i-C 3
H
7 2-(4 '-dimethylaminocarbonyl)eth-1-yl A. 1560 i-C 3
H
7 2-(2 '-aminothiocarbonyl)eth-1-yl A. 1561 li-C 3
H
7 2-(3 '-aminothiocarbonyl)eth-1-y.
A. 1562 i-C 3
H
7 2-(4 '-aminothiocarbonyl)eth-1-y.
A. 1563 i-C 3
H
7 2-(2 '-methylsulfonyl)eth-1-yl A.1564 i-C 3
H
7 2-(3'-methylsulfonyl)eth-1-yl A. 1565 i-C 3
H
7 2-(4 '-methylsulfonyl)eth-1-yl A.1566 i-C 3
H
7 3-phenoxyprop-1-yl A. 1567 i-C 3
H
7 3-(2 '-chlorophenoxy)prop-1-yl A. 1568 i-C 3
H
7 3-(3 '-chlorophenoxy)prop-1-yl 156 i- 3 H '-chiorophenoxy)prop--y.
A.1570 i-C 3
H
7 3-(3',5',dichlorophenoxy)prop-1-yl A. 1571 i-C 3
H
7 3-(2 '-cyanophenoxy)prop-1-yl A. 1572 i-C 3
H
7 3-(3 '-cyanophenoxy)prop-1-yl A. 1573 i-C 3
H
7 3-(4 '-cyanophenoxy)prop-1-yl A. 1574 i-C 3
H
7 3-(2 '-methylphenoxy)prop-1-yl A. 1575 i-C 3
H
7 3- (3 '-methylphenoxy)prop-1-yl A. 1576 i-C 3
H
7 3-(4 '-methylphenoxy)prop-1-yl A. 1577 i-C 3
H
7 3-(2 '-methoxyphenoxy)prop-1-yl A. 1578 i-C 3
H
7 3-(3 '-methoxyphenoxy)prop-1-yl A. 1579 i-C 3
H
7 3-(4 '-methoxyphenoxy)prop-1-yl A. 1580 i-C 3
H
7 3-(2 '-trifluoromethylphenoxy)prop-1-yl A. 1581 i-C 3
H
7 3-(3 '-trifluoromethylphenoxy)prop-1-yl A. 1582 i-C 3
H
7 3-(4 '-trifluoromethylphenoxy)prop-1-yl A.1583 i-C 3
H
7 4-phenoxybut-1-yl A.1584 i-C 3
H
7 2-phenyleth-1-yl A. 1585 i-C 3
H
7 2-(2 '-chlorophenyl)eth-1-yl A.1586 i-C 3
H
7 2-(3'-chlorophenyl)eth-1-yl A. 1587 i-C 3
H
7 2-(4 '-chlorophenyl)eth-1-yl A.1588 i-C 3
H
7 2-(3',5'-dichlorophenyl)eth-1-yl A.1589 i-C 3
H
7 2-(2 '-cyanophenyl)eth-1-yl A.1590 i-C 3
H
7 2-(3'-cyanophenyl)eth-1-yl A.1591 i-C 3
H
7 2-(4 '-cyanophenyl)eth-1-yl A.1592 i-C 3
H
7 2-(2'-methylphenyl)eth-1-yl A.1593 i-C 3
H
7 2-(3'-methylphenyl)eth-1-yl A.1594 i'-C 3
H
7 2-(41-methylphenyl)eth-1-yl 0050/46043 153 No.R24 A. 1595 i-C 3
H
7 2-(2'-methoxyphenyl)eth--y.
A.1596 li-C 3
H
7 2-(3'-methoxyphenyl)eth-1-yl A. 1597 i-C 3
H
7 2-(4 '-methoxyphenyl)eth-1-yl A. 1598 i-C 3
H
7 2-(2 '-trifluoromethylphenyl)eth-1Nyl A. 1599 i-C 3
H
7 2-(3 '-trifluoromethypheny)eth1.yl A. 1600 i-C 3
H
7 2-(4 '-trifluoromethylpheny)eth1.yl A.1601 i-C 3
H
7 3-phenylprop-1-yl A. 1602 i-C 3
H
7 3-(2 '-chlorophenyl)prop-1-yl A. 1603 i-C 3
H
7 3-(3 '-chlorophenyl)prop-1-yl A.1604 i-C 3
H
7 3-(4 '-chlorophenyl)prop-1-y.
A. 1605 i-C 3
H
7 3-(2 '-cyanophenyl)prop-1-yl A. 1606 i-C 3
H
7 3-(3 '-cyanophenyl)prop-1-yl A. 1607 i-C 3
H
7 3-(4 '-cyanophenyl)prop-1-yl A.1608 i.-CA1 7 3-(2 -trifluoromethylp-henyil)prop-1-y1 A.1609 i-C 3
H
7 4-phenylbut-1-y.
A.1610 i-C 3
H
7 4-(4'-chlorophenyl)but-1-yl A. 1611 i-C 3
H
7 6-(4 '-chlorophenyl)hex-1-yl A.1612 i-C 3
H
7 2-pyridylmethyl A.1613 i-C 3
H
7 3-pyridylmethyl A.1614 i-C 3
H
7 4-pyridylmethyl A. 1615 i-C 3
H
7 4-chloropyridin-2-ylmethyl A. 1616 i-C 3
H
7 5-chloropyridin-2-ylmethyl A. 1617 i-C 3
H
7 6-chloropyridin-2-ylmethyl A. 1618 i-C 3
H
7 5-chloropyridin-3-ylmethyl A. 1619 i-C 3
H
7 6-chloropyridin-3-ylmethyl A. 1620 i-C 3
H
7 2-chloropyridin-4-ylmethyl A.1621 i-C 3
H
7 2-pyrimidinylmethyl A. 1622 i-C 3
H
7 4-chloropyrimidin-2-ylmethyl A. 1623 i-C 3
H
7 5-chloropyrimidin-2-ylmethyl A. 1624 i-0 3
H
7 2-chloropyrimidin-4-ylmethyl A. 1625 i-C 3
H
7 6-chloropyrimidin-4-ylmethyl A. 1626 i-C 3
H
7 A.1627 i-C 3
H
7 4-pyridazinylmethyl A.1628 i-C 3
H
7 2-pyrazinylmethyl A. 1629 i-C 3
H
7 5-chloropyrazin-2-ylmethyl A. 1630 i-C 3
H
7 6-chloropyrazin-2-ylmethyl A.1631 i-C 3
H
7 3-pyridazinylmethyl A. 1632 i-C 3
H
7 6-chloropyridazin-3-ylmethyl A. 16 33 i-C 3
H
7 1,3, 0050/46043 154 No.R24 A.1634 i-C 3
H
7 2-furylmethyl A.1635 i-C 3
H
7 3-furylmethyl A. 1636 i-C 3
H
7 4-bromofur-2-ylmethyl A. 1637 i-C 3
H
7 5-chlorofur-2-ylmethyl A.1638 i-C 3
H
7 2-thienylmethy.
A.1639 i-C 3
H
7 3-thienylmethy.
A. 1640 i-C 3
H
7 5-methylthien-3-ylmethyl A. 1641 i-C 3
H
7 5-chlorothien-2-ylmethyl A. 1642 i-C 3
H
7 2-chlorothien-4-ylmethyl A.1643 i-C 3
H
7 2-pyrrolylmethyl A.1644 i-C 3
H
7 3-pyrrolylmethyl A.1645 i-C 3
H
7 2-oxazolylmethyl A. 1646 i-C 3
H
7 4-methyloxazol-2-ylmethyl A.1647 -C% 3
H
7 5-methyioxazoi-2-ylmethy.
A. 1648 i-C 3
H
7 4-chloro--oxazol-2-ylmethyl A. 1649 i-C 3
H
7 5-chloro-oxazol-2-ylmethyl A.1650 i-C 3
H
7 4-oxazolylmethyl A. 1651 i-C 3
H
7 2-methyloxazol-4-ylmethyl A. 1652 i-C 3
H
7 5-methyloxazol-4-ylmethyl A. 1653 i-C 3
H
7 2 -chloro-oxazol-4-ylmethyl A. 1654 i-C 3
H
7 5-chloro-oxazol-4-ylmethyl A.1655 i-C 3
H
7 A. 1656 i-C 3
H
7 A. 1657 i-C 3
H
7 A. 1658 i-C 3
H
7 A. 1659 i-C 3
H
7 A.1660 i-C 3
H
7 2-thiazolylmethyl A. 1661 i-C 3 H 7 4-methylthiazol-2-ylnethyl A. 1662 i-C 3
H
7 5-xethylthiazol-2-ylmethyl A. 1663 i-C 3
H
7 4-chlorothiazol-2-ylmethyl A. 1664 i-C 3
H
7 5-chlorothiazol-2-ylmethyl A.1665 i-C 3
H
7 4-thiazolylmethyl A. 1666 ji-C 3
H
7 2-methylthiazol-4-ylmethy.
A. 1667 i-C 3
H
7 5-methylthiazol-4-ylnethyl A. 1668 i-C 3
H
7 2-chlorothiazol-4-ylmethyl A. 1669 i-C 3
H
7 5-chlorothiazol-4-ylmethyl A.1670 i-C 3
H
7 A. 1671 i-C 3
H
7 A. 1672 i-C 3
H
7 14-methylthiazol-5-ylmethyl 0050/46043 155 N~o.R24 A. 1673 i-C 3
H
7 2 A. 1674 i-C 3
H
7 A.1675 i-C 3
H
7 3-isoxazolylmethyl A. 1676 i-C 3
H
7 4 -methylisoxazol-3-ylmethyl A. 1677 i-C 3
H
7 5-methylisoxazol-3-ylmethyl A.1678 i-C 3
H
7 4-chloro-isoxazol-3-ylmethyl A. 1679 i-C 3
H
7 5-chloro-isoxazol-3-ylmethyl A.1680 i-C 3
H
7 4-isoxazolylmethyl A. 1681 i-C 3
H
7 3-methylisoxazol-4-ylmethy.
A.1682 i-C 3
H
7 5 -methylisoxazol-4 -ylmethyl A. 1683 i-C 3
H
7 3 -chloro-isoxazol-4-ylmethyl A. 1684 i-C 3
H
7 5-chloro-isoxazol-4-ylmethyl A.1685 i-C 3
H
7 A O*18 3
H
7 3 A. 1687 i-C 3
H
7 4 A. 1688 i-C 3
H
7 3 A. 1689 i-C 3
H
7 4 A. 1690 i-C 3
H
7 3-isothiazolylmethyl A.1691 i-C 3
H
7 4-methyl-isothiazol-3-ylmethyl A. 1692 i-C 3
H
7 5-methyl-isothiazol-3-ylmethyl A. 1693 i-C 3
H
7 4 -chloro-isothiazol-3-ylmethyl A.1694 i-C 3
H
7 5-chloro-isothiazol-3-ylmethyl A. 1695 i-C 3
H
7 4-isothiazolylmethyl A. 1696 i-C 3
H
7 3-methyl-isothiazol-4-ylmethyl A.1697 i-C 3
H
7 5-methyl-isothiazol-4 -ylmethyl A. 1698 i-C 3
H
7 3 -chloro-isothiazol-4-ylmethyl A. 1699 i-C 3
H
7 5-chloro-isothiazol-4-ylmethyl A. 1700 i-C 3
H
7 A. 1701 i-C 3
H
7 A. 1702 i-C 3
H
7 4-methy1-isothiazol-5-ylmethyl A. 1703 i-C 3
H
7 3 A. 1704 i-C 3
H
7 A.1705 i-C 3
H
7 4"imidazolylmethyl A.1706 i-C 3
H
7 1-phenylpyrazol-3 -ylmethyl A. 1707 i-C 3
H
7 1-methylimidazol-4-ylmethyl A. 1708 i-C 3
H
7 l-phenyl-1,2,4-triazol-3..ylmethyI A.1709 i-C 3
H
7 1,2,4-oxadiazol-3-ylmethyl A. 1710 i-C 3
H
7 5-chloro-1,2,4-oxadiazol-3..ylmethyl 1711 li-C 3
H
7 5-methyl-1,2,4-oxad iazol-3.ylmethyl hLu
Q~~
0050/46043 156 No.R24 A. 1712 i-C 3
H
7 5-trifluoromethyl-1 4-oxadiazol-3-ylmethyl A. 1713 i-C 3
H
7 1,3, 4 -oxadiazol-2-ylmethy.
A.1714 i-C 3
H
7 5-chloro-1, 3, 4 -oxadiazol:2-ylmethyl A. 1715 i-C 3
H
7 5-methyl-i, 3, 4 -oxadiazol-2-ylmethyl A. 1716 i-C 3
H
7 5-methoxy-1,3, 4 -oxadiazol-2-ylmethyl A. 1717 i-C 3
H
7 1,2 4 -thiadiazol-3-ylmethyl A. 1718 i-C 3
H
7 5-chloro-1,2,4thiadiazol.3.ylmethyl A.1719 i-C 3
H
7 5-methyl-i, 2, 4 -thiadiazol-3-ylmethyl A. 1720 i-C 3
H
7 1,3 4 -thiadiazol-2-ylmethyl A. 1721 i-C 3
H
7 5-chloro-1,3,4-thiadiazol.2-ylmethyl A. 1722 i-C 3
H
7 5-methyl-l,3,4-thiadiazol2ylmethyl A. 1723 i-C 3
H
7 5-cyano-1,3, 4 -thiadiazol-2-ylmethyl A.1724 i-C 3
H
7 2-(2'-pyridinyloxyeth...1..l A.1725 i-C 3
H
7 2 3 '-pyridinyloxy)eth-1-yl A.1726 i-C 3
H
7 2-(4 '-pyridinyloxy)eth-1-yl A.1727 i-C 3
H
7 2- -pyrimidinyloxy) eth- 1-yl A. 1728 i-C 3
H
7 2-(4 '-pyrimidinyloxy)eth-1-yl A. 1729 i-C 3
H
7 2-(5 '-pyrimidinyloxy)eth-1-yl A.1730 i-C 3
H
7 2-(2 '-pyrazinyloxy)eth-1-yl A. 1731 i-C 3
H
7 2-(2 '-pyridazinyloxy)eth1.yl A.1732 i-C 3
H
7 2-(3 '-pyridazinyloxy)eth1.yl A.1733 i-C 3
H
7 2 3 ,5'-triazinyloxy)eth1.yl A.1734 i-C 3
H
7 2 -(5'-methylisoxazol-3...yloxy)eth.1.yl A.1735 i-C 3
H
7 2 -(5'-chloro-isoxazol-3.yloxy)eth.1.yl A.1736 i-C 3
H
7 2 2 '-methoxythiazol4yloxyth th....yl A. 1737 i-C 3
H
7 2-(4 '-chloro-oxazol-2 '-yloxy)eth-1-yl eth-1-yl A. 1739 i-C 3 F1 7 1 -phenylpyrazol-3 '-yloxy)eth-1-yl A.1740 i-C 3
H
7 C 6
H
A.1741 i-C 3
H
7 2-Cl-C 6
H
4 A.1742 i-C 3 H 7 3-Cl-C 6
H
4 A.1743 i-C 3
H
7 4-Cl-C 6
H
4 A.1744 i-C 3
H
7 2,3-C1 2
-C
6
H
3 A.1745 i-C 3
H
7 2,4-C1 2
-C
6
H
3 A.1746 i-C 3
H
7 2,5-C1 2
-C
6
H
3 A.1747 i-C 3
H
7 3,4-Cl 2
-C
6
H
3 A.1748 i-C 3
H
7 3,5-C1 2
-C
6
H
3 i-C 3
H
7 4-CN-C 6
H
4 1,I A.14 0050/46043 157 No.R
R
4 A.1750 i-C 3
H
7 2-N0 2
-C
6
H
4 A.1751 i-C 3
H
7 3-N0 2
-C
6
H
4 A.1752 i-C 3
H
7 4-N0 2
-C
6
H
4 A.1753 i-C 3
H
7 2,4-(N0 2 2
-C
6
H
3 A.1754 i-C 3
H
7 2-CH 3
-C
6
H
4 A.1755 i-C 3
H
7 3-CH 3
-C
6
H
4 A.1756 i-C 3
H
7 4-CH 3
-C
6
H
4 A.1757 i-C 3
H
7 2,3-(CH 3 2
-C
6
H
3 A.1758 i-C 3
H
7 2,4-(CH 3 2
-C
6
H
3 A.1759 i-C 3
H
7 2,5-(CH 3 2
-C
6
H
3 A.1760 i-C 3
H
7 2,6-(CH 3 2
-C
6
H
3 A.1761 i-C 3
H
7 2-C 6
H
5
-C
6
H
4 A.1762 i-C 3
H
7 3-C 6
H
5
-C
6
H
4 A. 1 -76 3 i-C 3
H
7 4-C 6
H
5
-C
6
H
4 A.1764 ji-C 3
H
7 3-OCH 3
-C
6
H
4 A.1765 i-C 3
H
7 4-OCH 3
-C
6
H
4 A.1766 i-C 3
H
7 3-acetYl-C 6
H
4 A.1767 i-C 3
H
7 4-acetyl-C 6
H
4 A. 1768 i-C 3
H
7 3-methoxycarbonyl-C 6
H
4 A. 1769 i-C 3
H
7 4-methoxycarbonyl-C 6
H
4 A.1770 i-C 3
H
7 3-CF 3
-C
6
H
4 A.1771 i-C 3
H
7 4-CF 3
-C
6
H
4 A.1772 i-C 3
H
7 2-naphthyl A. 1773 i-C 3
H
7 6-chloropyridazin-3 -yl A. 1774 i-C 3
H
7 5-chloropyrazin-2-yl A.1775 i-C 3
H
7 quinolin-2-yl A. 1776 i-C 3
H
7 2, 5-dimethylpyrazin-3-yl A.1777 i-C 3
H
7 pyrazin-2-yl A.1778 i-C 3
H
7 3-chloropyrid-2-yl A.1779 i-C 3
H
7 6-chloropyrid-2-yl A. 1780 i-C 3
H
7 4-trifluoromethyl, 6-chloropyrid-2-yl A. 1781 i-C 3
H
7 4-trifluoromethylpyrid2.yl A. 1782 i-C 3
H
7 6-trifluoromethylpyrid2..yl A.1783 i-C 3
H
7 6-methoxypyrid-2-yl A.1784 i-C 3 11 7 5-chloropyrid-2-yl A.1785 i-C 3
H
7 pyrid-2-yl A.1786 i-C 3
H
7 benzothiazol-2-yl A. 1787 i-C 3
H
7 7-chloroquinolin-4-yl -A A.1788 i-C 3
H
7 3-nitropyrid-2-yl 4,1 0050/46043 No.R24 A. 1789 i-C 3
H
7 pyrrol-3-yl A. 1790 i-C 3
H
7 pyrrol-2-yl A. 1791 i-C 3
H
7 2, 6-dioctylpyrid-4.yl A.1792 i-C 3
H
7 5-nitropyrid-2-yl A.1793 i-C 3
H
7 pyrid-4-yl A.1794 i-C 3
H
7 pyrid-3-yl A.1795 i-C 3
H
7 pyrimidin-2-yl A.1796 i-C 3
H
7 pyrimidin-4-yl A.1797 i-C 3
H
7 quinazolin-4-yl A. 1798 i-C 3
H
7 6-chloropyrimidin-4.yl A. 1799 i-C 3
H
7 6-methoxypyrimidin-4.yl A. 1800 i-C 3
H
7 2,5, 6-trichloropyrimidin-4..yl A. 1801 i-C 3
H
7 2, 6-dimethylpyrimidin-4-yl A.1802 i C 3 H 7 2-methyl, 6-chloropyrimidin-4-yl A. 1803 i-C 3
H
7 2-methyl, 6-ethoxypyrimidin-4-yl A.1804 i-C 3
H
7 4,5, 6-trichloropyrimidin2..yl A. 1805 i-C 3
H
7 4, 6-dimethoxypyrimidin2.yl A. 1806 i-C 3
H
7 4, 6-dimethylpyrimidin2..yl A. 1807 i-C 3
H
7 4, 6-dichloropyrimidin2.yl A.1808 i-C 3
H
7 4-methyl, 6-methoxypyrimidin2.yl A. 1809 i-C 3
H
7 4-chioro, 6-methoxypyrimidin2.yl A. 1810 i-C 3
H
7 6-chloroquinoxalin-2.yl A.1811 i-C 3
H
7 4,-ethooy-1, ,5-triai..2..yl A.1812 i-C 3
H
7 4 -ethoxy-1,3,5-triazin2yl A.1813 i-C 3
H
7 4-ethoxy, -lr-1,3,5-triazin....y A.1816 i-C 3
H
7 isoxaz ol-3-yl A.1817 i-C 3
H
7 thien-2-yl A.1818 i-C 3
H
7 fur-2-yl A.1819 i-C 3
H
7 A. 1820 i-C 3
H
7 -1-chloropropen-3-yl A.1821 i-C 3
H
7 (E)-4-(4-chlorophelbut... 2en1.yl A.1822 i-C 3
H
7 propyn-3-yl A.1823 i-C 3
H
7 methylcarbonyl A.1824 i-C 3
H
7 ethylcarbonyl A.1825 i-C 3
H
7 n-propylcarbonyl A.1826 i-C 3
H
7 i-propylcarbonyl A.1827 i-C 3
H
7 n-butylcarbonyl 0050/46043 159 No.R24 A.1828 i-C 3
H
7 s-butylcarbonyl A.1829 i-C 3
H
7 i-butylcarbonyl A.1830 i-C 3
H
7 t-butylcarbonyl A.1831 i-C 3
H
7 n-pentylcarbonyl A.1832 i-C 3
H
7 i-pentylcarbonyl A.1833 i-C 3
H
7 neo-pentylcarbonyl A.1834 i-C 3
H
7 n-hexylcarbonyl A.1835 i-C 3
H
7 n-octylcarbonyl A.1836 i-C 3
H
7 1-propenylcarbonyl A. 1837 i-C 3
H
7 2-penten-1-ylcarbonyl A. 1838 i-C 3
H
7 2, 5-heptadien-1-ylcarbonyl A.1839 i-C 3
H
7 benzoyl A.1840 i-C 3
H
7 2-chlorobenzoyl A.1841 iJ-C 3
H
7 3 -chIAor obenzoyl A.1842 i-C 3
H
7 4-chlorobenzoyl A.1843 i-C 3
H
7 2-cyanobenzoyl A.1844 i-C 3
H
7 3-cyanobenzoyl A.1845 i-C 3
H
7 4-cyanobenzoyl A.1846 i-C 3
H
7 4-methoxybenzoyl A.1847 i-C 3
H
7 2-pyridylcarbonyl A.1848 i-C 3
H
7 3-pyridylcarbonyl A.1849 i-C 3
H
7 4-pyridylcarbonyl A. 1850 i-C 3
H
7 2 -pyrimidinylcarbonyl A.1851 i-C 3
H
7 2-oxazolylcarbonyl A. 1852 i-0 3
H
7 4 A.1853 i-0 3
H
7 methylsulfonyl A.1854 i-C 3
H
7 ethylsulfonyl A.1855 i-C 3
H
7 n-propylsulfonyl A.1856 i-C 3
H
7 i-propylsulfonyl A.1857 i-C 3
H
7 n-butylsulfonyl A.1858 i-C 3
H
7 t-butylsulfonyl A.1859 i-C 3
H
7 n-pentylsulfonyl A.1860 i-C 3
H
7 neo-pentylsulfonyl A.1861 i-C 3
H
7 n-hexylsulfonyl A.1862 i-C 3
H
7 n-octylsulfonyl A.1863 i-C 3
H
7 phenylsulfonyl A. 1864 i-C 3
H
7 2-chlorophenylsulfonyl A. 1865 i-C 3
H
7 3-chlorophenylsulfonyl 1866 ji-C 3
H
7 4-chlorophenylsulfonyl sV) 0050/46043 160 No.R24 A. 1867 i-C 3
H
7 2-cyanophenylsulfonyl A. 1868 i-C 3
H
7 3-cyanophenylsulfonyl A. 1869 i-C 3
H
7 4-cyanophenylsulfonyl A.1870 i-C 3
H
7 2-pyridylsulfonyl A.1871 i-C 3
H
7 3-pyridylsulfonyl A.1872 i-C 3
H
7 4-pyridylsulfonyl A. 1873 i-C 3
H
7 2-pyrimidinylsulfonyl A.1874 i-C 3
H
7 4-oxazolylsulfonyl A. 1875 i-C 3
H
7 5-chlorothiazol-2ylsulfonyl A.1876 i-C 3
H
7 2-t-C 4
H
9
-C
6
H
4
-CH
2 A.1877 i-C 3
H
7 3-t-C 4
H
9
-C
6
H
4
-CH
2 A.1878 i-C 3
H
7 4-t-C 4
H
9
-C
6
H
4
-CH
2 A. 1879 ii-C 3
H
7 2-(4 '-chlorothiazol-2 '-yloxy)eth-1-yl A.UQ 80iCHz-(i'L-niethylpyrazol-4'-yioxy)eth-1-yl A.1881 i-C 3
H
7 4-Br-C 6
H
4 A.1882 i-C 3
H
7 3,5-(CH 3 2
-C
6
H
3 A.1883 i-C 3 H7 4-C 2
H
5
-C
6
H
4 A. 1884 i-C 3
H
7 3-dimethylaminocarbonyl-C 6
H
4 A. 1885 i-C 3
H
7 4-dimethylaminocarbonyl-C 6
H
4 A.1886 i-C 3
H
7 2-hydroxyprop-1-yl A. 1887 i-C 3
H
7 6-hydroxy-2-methylpyrimidin-4-ylmethyl A.1888 i-C 3
H
7 6-QH, 2-CH (0H 3 2 -pyrimidin-4-yl
-CH
2 A.1889 i-C 3
H
7 6-OH, 2-CH (CH 2 2 -pyrimidin-4-yl
-CH
2 A. 1890 i-C 3
H
7 5-(2 '-furan)pent-1-yl A. 1891 i-C 3
H
7 5-(2 '-N-methylpyrrol)pent-1-yl A.1892 i-C 3
H
7 [2-(4-C1-C 6
H
4 )oxazol-4-yl]-CH 2 A.1893 i-C 3
H
7 3-CF 3 -pyridin-2-yl A.1894 i-C 3
H
7 5-CF 3 -pyridin-2-yl A. 1895 i-C 3
H
7 6- (2 '-thienyl )hex-1-yl A. 1896 i-C 3
H
7 (E)-3-chlorobut-2-en-1-yl A. 1897 i-C 3
H
7 (Z)-3-chlorobut-2-en-1-yl A. 1898 ji-C 3
H
7 (E)-2-bromobut-2-en-1-yl A. 1899 i-C 3
H
7 (Z)-2-bromobut-2-en-1-yl A. 1900 i-C 3
H
7 (E)-1-chloroprop-1--en-3-yl A. 1901 i-C 3
H
7 (Z)-1-chloroprop-1-en-3-yl A.1902 i-C 3
H
7 but-1-en-3-yl A.1903 i-C 3
H
7
CH
2
CH
2 Br [A 1904 i-C 3
H
7
CH
2
CH
2
CH
2 Br A. 190 5 i-C 3
H
7
CH
2
CH
2
CH
2
CH
2 Br
U,
/V~
0050/46043 161 No.R24 A. 1906 i-C 3
H
7 2-methoxyprop-1-yl A.1907 i-C 3
H
7 2-ethoxyprop-1-yl A.-1908 i-C 3
H
7 2-isopropoxyprop-1-yl A.1909 i-C 3 H7 but-1-yn-3-yl A.1910 i-C 3
H
7 but-1-yn-4-yl A.1911 i-C 3
H
7 but-2-yn-4-yl A.1912 i-C 3
H
7 pent-1-yn-4-yl A.1913 i-C 3
H
7 pent-2-yn-4-yl A.1914 i-C 3
H
7 A.1915 i-C 3
H
7 A. 1916 i-C 3
H
7 E-2-chlorobut-2-en-1-yl A. 1917 i-C 3
H
7 Z-2-chlorobut-2-en-1-yl A. 1918 i-C 3
H
7 Z-1-chloroprop-1-en-3-yl A. 1919 1i-- 3
H
7 2-methylprop-1-en-3-yi A. 1920 i-C 3
H
7 2-chloroprop-1-en-3-yl A. 1921 i-C 3
H
7 2-bromoprop-1-en-3-yl A.1922 i-C 3
H
7 but-2-en-1-yl A.1923 i-C 3
H
7 but-3-en-1-yl A. 1924 i-C 3
H
7 1-iodoprop-1-yn-3-yl A. 1925 i-C 3
H
7 E-3-bromobut-2-en-1-yl A. 1926 i-C 3
H
7 Z-3-bromobut-2-en-1-yl A.1927 cyclopropyl
H
A.1928 cyclopropy.
CH
3 A.1929 cyclopropyl
C
2
H
A.1930 cyclopropyl n-C 3
H
7 A.1931 cyclopropyl i-C 3
H
7 A.1932 cyclopropyl cyclopropyl A.1933 cyclopropyl n-C 4 H9 A.1934 cyclopropyl
SCH
A.1935 cyclopropyl i-C 4
H
9 A.1936 cyclopropyl t-C 4
H
9 A.1937 cyclopropy. n-C 5
H
11 A.1938 cyclopropyl i-C 5 Hl 1 A.1939 cyclopropyl neo-C 5
H
11 A.1940 cyclopropy. cyclopentyl A.1941 cyclopropyl n-C 6 Hl 3 A.1942 cyclopropy. cyclohexyl A.1943 cyclopropyl n-C 8
H
17 A.1944 cyclopropyl
ICH
2
CH
2 Cl 0050/46043 162 No.R24 A. 1945 cyclopropyl
(CH
2 4 C1 A.1946 cyclopropyl
CH
2
CN
A.1947 cyclopropyl
CH
2
CH
2
CN
A.1948 cyclopropyl
(CH
2 3
CN
A.1949 cyclopropyl
(CH
2 4
CN
A.1950 cyclopropyl
(CH
2 6
CN
A. 1951 cyclopropyl cyclohexylmethyl A. 1952 cyclopropyl 2-cyclohexyleth-1-yl A. 1953 cyclopropyl cyclopropylmethyl A. 1954 cyclopropyl 2-cyclopropyleth-1-yl A. 1955 cyclopropyl 2-methoxyeth-1-yl A. 1956 cyclopropyl 2-ethoxyeth-1-yl A. 1957 cyclopropyl 2-isopropoxyeth-1-yl A. 1958 c y ciopropyl 3-methoxyprop-1-yi A. 1959 cyclopropyl 3-ethoxyprop-1-yl A. 1960 cyclopropyl 3-isopropoxyprop-1-yl A. 1961 cyclopropyl 4-methoxybut-1-yi A. 1962 cyclopropyl 4-isopropoxybut-1-yl 0050/ 46043 163 No.R24 A. 1963 cyclopropyl propen-3-yl A.1964 cyclopropyl but-2-en-.1-yl A. 1965 cyclopropyl 3-methylbut-2-en-1-yl A. 1966 cyclopropyl 2-vinyloxyeth-1-yl A. 1967 cyclopropyl allyloxyeth-1-yl A. 1968 cyclopropyl 2-trifluoromethoxyeth-1-yl A. 1969 cyclopropy. 3-trifluoromethoxyprop-.-yl A. 1970 cyclopropyl 4-difluoromethoxybut-1-yl A. 1971 Icyclopropyl hydroxycarbonylmethyl A. 1972 cyclopropyl methoxycarbonylmethyl A. 1973 cyclopropyl aminocarbonylmethyl A. 1974 cyclopropyl N-methylaminocarbonylmethy.
A. 1975 cyclopropyl N,N-dimethylaminocarbonyl-methyl A.*19760 cyclopropyl 2-hydroxycarbonyleth-1-yl A. 1977 cyclopropyl 2-methoxycarbonyleth-1-yl A. 1978 cyclopropyl 2-aminocarbonyleth-1-yl A. 1979 cyclopropyl 2-N-methylaminocarbonyleth-1-yl A. 1980 cyclopropyl 2-dimethylaminocarbonyleth-1-yl A.1981 cyclopropyl 2-aminoeth-1-yl A. 1982 cyclopropyl 2-aminoprop-1-yl A.1983 cyclopropyl 4-aminobut-1-yl A. 1984 cyclopropyl 3-dimethylaminoprop-1-yl A. 1985 cyclopropyl 4-aminothiocarbonylbut-1-yl A.1986 cyclopropy. 2-oxopropyl A.1987 Icyclopropyl cyclohexy.
A.1988 cyclopropyl cyclopropyl A.1989 cyclopropy. cyclopentyl A. 1990 cyclopropyl 2-methoxyiminoprop-1-yl A. 1991 cyclopropyl 2-methoxyiminoeth-1-yl A. 1992 cyclopropyl 6-aminocarbonylhex-1-yl A. 1993 cyclopropyl 3-aminothiocarbonylprop-1-yl A. 1994 cyclopropyl 2-aminothiocarbonyleth-1-yl A. 1995 cyclopropyl aminothiocarbonylmethyl A. 1996 cyclopropyl 4- N-dimethylamino) but-1-yl A. 1997 cyclopropyl 2-(methylthio)eth-1-yl A. 1998 cyclopropyl 2- (methylsulfonyl )eth-1-yl A. 1999 cyclopropyl 4-(methylthio)prop-1-yl A.2000 Icyclopropyl 4-(methylsulfonyl)prop-1-yl A.2001 Icyclopropyl lbenzy.
0050/46043 164 No. R 2
R
A. 2002 cyclopropyl 2-F-C 6
H
4
-CH
2 A.2003 cyclopropyl 3-F-C 6
H
4
-CH
2 A.2004 cyclopropyl 4-F-C 6
H
4
-CH
2 A.2 005 cyclopropyl 2, 3-F 2
-C
6
H
3
-CH
2 A.2006 cyclopropyl 2,4-F 2
-C
6
H
3
-CH
2 A. 2007 cyclopropyl 2, 5-F 2
-C
6
H
3
-CH
2 A.-2008 cyclopropyl 2, 6-F 2
-C
6
H
3
-CH
2 A.2009 lcyclopropyl 3,4-F 2
-C
6
H
3
-CH
2 A.2010 cyclopropy. 3,5-F 2
-C
6
H
3
-CH
2 A.2011 cyclopropyl 2-Cl-C 6
H
4
-CH
2 A.2012 cyclopropyl 3-Cl-C 6
H
4
-CH
2 A.2013 Icyclopropyl 4-Cl-C 6
H
4
-CH
2 A. 2014 cyclopropyl 2, 3-C1 2
-C
6
H
3
-CH
2 a.21 ZU.- cyciopropyl 2,4-Cl 2
-C
6
H
3
-CH
2 A. 2016 cyclopropyl 2, 5-C1 2
-C
6
H
3
-CH
2 A.2017 cyclopropyl 2,6-Cl 2
-C
6
H
3
-CH
2 A. 2018 cyclopropyl 3, 4-Cl 2
-C
6
H
3
-CH
2 A.2019 cyclopropyl 3,5-Cl 2
-C
6
H
3
-CH
2 A. 2020 cyclopropyl 2,3, 4-C1 3
-C
6
H
2
-CH
2 A. 2021 cyclopropyl 2,3, 5-C1 3
-C
6
H
2
-CH
2 A. 2022 cyclopropyl 2, 3, 6-C1 3
-C
6
H
2
CH
2 A. 2023 cyclopropyl 2,4, 5-C1 3
-C
6
H
2
-CH
2 A-2024 cyclopropyl 2,4,6-Cl 3
-C
6
H
2
-CH
2 A. 2025 cyclopropyl 3,4, 5-C1 3
-C
6
H
2
-CH
2 A-2026 cyclopropy. 2-Br-C 6
H
4
-CH
2 A-2027 cyclopropyl 3-Br-C 6
H
4
-CH
2 A-2028 cyclopropyl 4-Br-C 6
H
4
-CH
2 A. 2029 cyclopropyl 2, 3-Br 2
-C
6
H
3
-CH
2 A. 2030 cyclopropy. 2, 4-Br 2
-C
6
H
3
-CH
2 A-2031 cyclopropyl 2, 5-Br 2
-C
6
H
3
-CH
2 A-2 032 cyclopropyl 2, 6-Br 2
-C
6
H
3
-CH
2 A. 2033 cyclopropyl 3, 4-Br 2
-C
6
H
3
-CH
2 A. 2034 cyclopropyl 3, 5-Br 2
-C
6
H
3
-CH
2 A.2035 cyclopropyl 2-F, 3-Cl-C 6
H
3
-CH
2 A.2036 cyclopropyl 2-F, 4-C1-C 6
H
3
-CH
2 A.2037 cyclopropy. 2-F, 5-Cl-C 6
H
3
-CH
2 A.2038 cyclopropyl 2-F, 3-Br-C 6
H
3
-CH
2 A.2039 cyclopropyl 2-F, 4-Br-C 6
H
3
-CH
2 \kk A.2040 cyclopropyl 12-F, 5-Br-C 6
H
3
-H
I\
0 0050/46043 165 No. R 2
R
A. 2041 cyclopropyl 2-Cl, 3-Br-C 6
H
3
-CH
2 A.2042 cyclopropyl 2-Cl, 4-Br-C 6
H
3
-CH
2 A.2043 cyclopropyl 2-Cl, 5-Br-C 6
H
3
-CH
2 A.2044 cyclopropyl 3-F, 4-Cl-C 6
H
3
-CH
2 A.2045 cyclopropyl 3-F, 5-Cl-C 6
H
3
-CH
2 A.2046 Icyclopropyl 3-Fl 6-Cl-C 6
H
3
-CH
2 A.2047 cyclopropyl 3-F, 4-Br-C 6
H
3
-CH
2 A.2048 cyclopropyl 3-F, 5-Br-C 6
H
3
-CH
2 A.2049 cyclopropyl 3-F, 6-Br-C 6
H
3
-CH
2 A.2050 cyclopropyl 3-Cl, 4-Br-C 6
H
3
-CH
2 A.2051 cyclopropyl 3-Cl, 5-Br-C 6
H
3
-CH
2 A.2052 cyclopropyl 3-Cl, 6-Br-C 6
H
3
-CH
2 A.2053 cyclopropyl 4-F, 5-Cl-C 6
H
3
-CH
2 A.04 ylprpl4-,6-lCH7Ci A.2054 cyclopropyl 4-F, 5-Br-C 6
H
3
-CH
2 A.2055 cyclopropyl 4-F, 6-Br-C 6
H
3
-CH
2 A.2056 cyclopropyl 4-Cl, -Br-C 6
H
3
-CH
2 A.2057 cyclopropyl 5-F, 6-l-C 6
H
3
-CH
2 A.2058 cyclopropyl 5-F, 6-Br-C 6
H
3
-CH
2 A.2059 cyclopropyl 5-Cl, 6-Br-C 6
H
3
-CH
2 A.2060 cyclopropyl 3-r5-Cl, 5-Br-C 6
H-CH
2 A.2061 cyclopropyl 2-Br, 6 4
-CH
2 A.2 063 cyclopropyl 3-CN-C 6
H
4
-CH
2 A.2063 cyclopropyl 4-CN-C 6
H
4
-CH
2 A.2064 cyclopropyl 2-N-C 6
H
4
-CH
2 A.2065 cyclopropyl 3-N0 2
-C
6
H
4
-CH
2 A.2066 cyclopropyl 4-N0 2
-C
6
H
4
-CH
2 A.2067 cyclopropyl 2-CH 3
-C
6
H
4
-CH
2 A.2068 cyclopropyl 3-CH 3
-C
6
H
4
-CH
2 A.2069 cyclopropyl 4-CH 3
-C
6
H
4
-CH
2 A.2070 cyclopropyl 2,-CH 3
-C
6 H -CH 2 A.2071 cyclopropyl 2,4-(CH 3 2
-C
6
H
3
-CH
2 A. 2073 cyclopropyl 2,5- (CH 3 2
-C
6
H
3
-CH
2 A.2073 cyclopropyl 2,6-(CH 3 2
-C
6
H
3
-CH
2 A.2074 cyclopropyl 3,4-(CH 3 2
-C
6
H
3
-CH
2 A.2075 cyclopropyl 3,5-(C11 3 2
-C
6
H
3
-CH
2 A.2076 cyclopropyl 2-C 5 -C3C 6 H3-CH 2 A. 2078 cyclopropyl 3-C 2
H
5
-C
6
H
4
-CH
2 A.2078 cyclopropyl 4-C 2
H
5
-C
6
H
4
-CH
2 0050/46043 166 No.R24 A.2080 cyclopropyl 2-i-C 3
H
7
-C
6
H
4
-CH
2 A.2081 cyclopropyl 3-i-C 3
H
7
-C
6
H
4
-CH
2 A.2082 cyclopropy. 4-i.-C 3
H
7
-C
6
H
4
-CH
2 A. 2083 cyclopropyl 2 -cyclohexyl-C 6
H
4
-CH
2 A. 2084 cyclopropyl 3-cyclohexyl-C 6
H
4
-CH
2 A. 2085 cyclopropyl 4 -cyc lohexyl-C 6
H
4
-CH
2 A. 2086 cyclopropyl 2-vinYl-C 6
H
4
-CH
2 A. 2087 cyclopropy. 3-vinyJ.-C 6
H
4
-CH
2 A. 2088 Icyclopropyl 4-vinyl-C 6
H
4
-CH
2 A. 2089 cyclopropyl 2-allYl-C 6
H
4
-CH
2 A. 2090 cyclopropyl 3-allYl-C 6
H
4
-CH
2 A. 2091 cyclopropyl 4-allYl-C 6
H
4
-CH
2 A. 2092 cyclopropyl 2-C 6
H
5
-C
6
H
4
-CH
2 A. 2093 cyciopropyl 3-C 6
H
5
-C
6
H
4
-CH
2 A. 2094 cyclopropyl 4-C 6
H
5
-C
6
H
4
-CH
2 A.2095 cyclopropyl 3-CE 3 5-t-C 4 Hg-C 6
H
3
-CH
2 A.2096 cyclopropyl 2-OH-C 6
H
4
-CH
2 A.2097 cyclopropyl 3-OH-C 6
E
4
-CH
2 A.2098 cyclopropyl 4-OH-C 6
H
4
-CH
2 A. 2099 cyclopropyl 2-OCH 3
-C
6
E
4
-CH
2 A. 2100 cyclopropy. 3-OCH 3
-C
6
H
4
-CH
2 A.2101 cyclopropyl 4-OCH 3
-C
6
H
4
-CE
2 A.2102 cyclopropyl 2, 3- (OCH 3 2
-C
6
H
3
-CH
2 A.2103 cyclopropyl 2, 4- (QCH 3 2
-C
6
H
3
-CH
2 A.2104 cyclopropyl 2,5-(OC 3 2
-C
6 3
-CH
2 A.2105 cyclopropyl 3,4-(OCH 3 2
-C
6
E
3
-CH
2 A.2106 cyclopropyl 3,5-(OCH 3 2
-C
6
E
3
-CH
2 A.2107 cyclopropyl 3,4, 5- (OCH 3 3
-C
6
H
2
-CH
2 A. 2108 cyclopropyl 2-0C 2
H
5
-C
6
H
4
-CH
2 A. 2109 cyclopropyl 3-0C 2
H
5
-C
6
H
4
-CH
2 A.2110 cyclopropyl 4-0C 2
H
5
-C
6
E
4
-CH
2 A.2 111 cyclopropyl 2-0- (n-C 3
H
7
-C
6
H
4
-CH
2 A.2112 cyclopropyl 3-O-(n-C 3
H
7
)-C
6
H
4
-CH
2 A.2113 cyclopropyl 4-O-(n-C 3
H
7
)-C
6
H
4
-CH
2 A.2114 cyclopropyl 2-O-(i-C 3
H
7
)-C
6
H
4
-CH
2 A.2115 cyclopropyl 3-0- (i-C 3
H
7
-C
6
E
4
-CH
2 A.2116 cyclopropyl 4-O-(i-C 3
H
7
)-C
6
H
4
-CH
2 A.2117 cyclopropyl 4-O-(n-C 4
H
9
)-C
6
H
4
-CH
2 A.2118 cyclopropyl 3-0-(t-C 4
H
9
)-C
6
H
4
-CH
2 0050/46043 167 No.R24 A. 2119 cyclopropy. 4-0- (n-C 6 Hl 3
-C
6
H
4
-CH
2 A. 2120 cyclopropyl 2-O-allYl-C 6
H
4
-CH
2 A. 2121 cyclopropyl 3-O-allYl-C 6
H
4
-CH
2 A. 2122 cyclopropyl 4-O-allYl-C 6
H
4
-CH
2 A.2123 cyclopropyl 2-CF 3
-C
6
H
4
-CH
2 A.2124 cyclopropyl 3-CF 3
-C
6
H
4
-CH
2 A.2125 cyclopropyl 4-CF 3
-C
6
H
4
-CH
2 A. 2126 cyclopropyl 2-acetyl-C 6
H
4
-CH
2 A. 2127 cyclopropyl 3-acetyl-C 6
H
4
-CH
2 A. 2128 cyclopropyl 4-acetyl-C 6
H
4
-CH
2 A. 2129 cyclopropyl 2-methoxycarbonyl-C 6
H
4
-CH
2 A. 2130 cyclopropyl 3-methoxycarbonyl-C 6
H
4
-CH
2 A. 2131 cyclopropyl 4-methoxycarbonyl-C 6
H
4
-CH
2 A. 241 3 2 cyclopropyl Z-aminocarbonyi-C 6
H
4
-CH
2 A. 2133 cyclopropyl 3-aminocarbonyl-C 6
H
4
-CH
2 A. 2134 cyclopropyl 4-aminocarbonyl-C 6
H
4
-CH
2 A. 2135 cyclopropyl 2-dimethylaminocarbonyl-C 6
H
4
-CH
2 A. 2136 cyclopropyl 3-dimethylaminocarbonyl-C 6
H
4
-CH
2 A. 2137 cyclopropyl 4-dimethylaminocarbonyl-C 6
H
4
-CH
2 A.2138 cyclopropyl 2-(N-methylaminocarbony1)-C 6
H
4
-CH
2 A. 2139 cyclopropyl 3- (N-methylaniinocarbonyl
)-C
6
H
4
-CH
2 A. 2140 Icyclopropyl 4- (N-methylaminocarbonyl)
-C
6
H
4
-CH
2 A.2141 cyclopropyl 2-H 2
N-C
6
H
4
-CH
2 A.2142 cyclopropyl 3-H 2
N-C
6
H
4
-CH
2 A.2143 cyclopropyl 4-H 2
N-C
6
H
4
-CH
2 A. 2144 cyclopropyl 2-aminothiocarbonyl-C 6
H
4
-CH
2 A. 2145 cyclopropyl 3-aminothiocarbonyl-C 6
H
4
-CH
2 A. 2146 cyclopropyl 4-aminothiocarbonyl-C 6
H
4
-CH
2 A. 2147 cyclopropyl 2-methoxyiminomethyl-C 6
H
4
-CH
2 A. 2148 cyclopropyl 3-methoxyiminomethyl-C 6
H
4
-CH
2 A. 2149 cyclopropyl 4-methoxyiminomethyl-C 6
H
4
-CH
2 A. 2150 cyclopropyl 2-formyl-C 6
H
4
-CH
2 A.2151 cyclopropyl 3-formyl-C 6
H
4
-CH
2 A. 2152 cyclopropyl 4-formyl-C 6
H
4
-CH
2 A.2153 cyclopropyl 1 -methoxyiminoeth-1 '-Yl)-C 6
H
4
-CH
2 A.2154 cyclopropyl 1 -methoxyiminoeth-1 '-Yl)-C 6
H
4
-CH
2 A.2155 cyclopropyl 1 -methoxyiminoeth-1 '-Yl)-C 6
H
4
-CH
2 A. 156cyclopropyl 2-SCH 3
-C
6
H
4
-CH
2 A.257cyclopropyl 3SCH 3
-C
6
H
4
-CH
2 0050/46043 168 LNo. j R 2
R
r
I
8 cyc lopropyl 4-SCH 3
-C
6
H
4
-CH
2 4 A.2159 cyclopropyl 2 -SO 2
CH
3
-C
6
H
4
-CH
2 I i A. 27L16 cyc lopropyl 3 -SO 2
CH
3
-C
6
H
4
-CH
2 1* 4. A.2 161 cyc lopropyl 4-SO2CH 3
-C
6
H
4
-CH
2 I i A. 2162 cyc lopropyl 2-OCF 3
-C
6
H
4
-CH
2 A.-2163 cyclopropyl 3 -OCF 3
-C
6
H
4
-CH
2
I
A.2141' cyc lopropyl 14 -OCF 3
-C
6
H
4
-CH
2
I
A. 2165~ A. 2 166 cyc lopropyl cyc lopropyl 2 -OCHF 2
-C
6
H
4
-CH
2 A .2 1 7 cy l op r p y l -O C H F -C H -C H 2, A. 2167 cyclopropyl 3-,4-OCF 2
-C
6
H
4
-CH
2 A.2169 cyclopropyl 3-CF 3 4-OCF-CH
-H
[A.2 169 cyclopropyl 1-naphthyl-CH 2 A2 1701 cyc."lopropyl 2-nphthoyet-H 2 A.2172 cyclopropy. 2-phenhooxye eh1 A. 2172 cyclopropyl 2- (2 -chiorophenoxy) eth-1-yl A.2174 cyclopropyl 2-(3 '-chlorophenoxy)eth.1.yl A. 2174 cyclopropyl 2- (4 '5-chicorophenoxy) th- A.2 175 cyclopropyl 5 -dicnheoopnoxy)eth .1..y A. 2176 cyclopropyl 2- (2 -cyanophenoxy) eth-1-yl A.2178 cyclopropyl 2-(3 '-cyanophenoxy)eth1.yl A.2 178 cyclopropyl 2-(4 '-ceyanphenoxy)eth1.yl A. 2179 cyclopropyl 2- (2'-methyiphenoxy) eth-1-yl A. 2180 cyclopropyl 2- (3'-methyiphenoxy) eth-1-yl A. 2181 cyclopropyl 2- (4'-mebtyphenoxy) eth-1-yl A.2183 cyclopropyl 2-(3 '-t-butylphenoxy)eth-1.yl A.2184 cyclopropyl 2-(4 '-ntbtyphenoxy)eth..1..yl A.2185 cyclopropyl 2-(2 '-nitrophenoxy)eth.1.yl A. 2185 cyclopropyl 2- (3'-nitrophenoxy) eth-1-yl A.2187 cyclopropyl 2-(4 '-nitroxphenoxy)eth-1yl A. 2187 cyclopropyl 2- (2 -methoxyphenoxy) eth-1-yl A. 2188 cyclopropyl 2- (3'-methoxyphenoxy) eth-1-yl A.2190 cyclopropyl 2- (4 '-thloy ephenoxy) th-1-yl A. 2190 cyclopropyl 2- (2 -trifluoromethylphenoxy) eth-1-yl A. 2191 cyclopropyl 2- (3 -trifluoromethylphenoxy) eth-1-yl A 21092 cy1 oroy 2-41tilooehlpeoyeh.1.
6'
A
A. 2194 A. 2195 A. 2196 cy UUPr opyl cyc lopropyl cyclopropyl I z-(zl-acetylphenoxy)eth-1-yl
I
2- -acetyiphenoxy) eth- 1-y.
I -(4-tlhnoyeh1 2-(2 '-methoxycarbonyl)eth1..vl 0050/46043 169 No.R24 A.2197 cyclopropy. 2-(3 '-methoxycarbonyl)eth...>y1 A.2198 cyclopropyl 2-(4 '-methoxycarbonyl)eth.1.yl A. 2199 cyclopropyl 2- (2 '-dimethylaminocarbonyl )eth-1-yl A. 2200 cyclopropyl 2- -dimethylaminocarbonyl )eth-1-yl A. 2201 cyclopropyl 2- (4 '-dimethylaminocarbonyl )eth-1-yl A.2202 cyclopropyl 2-(2 '-aminothiocarbonyl)eth1.yl A.2203 cyclopropyl 2-(3 '-alninothiocarbonyl)eth-1.yl A.2204 cyclopropyl 2-(4 '-aminothiocarbonyl)eth1..yl A.2205 cyclopropyl 2-(2 '-methylsulfony)eth1.yl A.2206 cyclopropyl 2-(3 '-methylsulfonyl)eth-1i...yl A.2207 cyclopropyl 2 4 '-methylsulfonyl)eth1..yl A. 2208 cyclopropyl 3 -phenoxyprop-1-yl A. 2209 cyclopropyl 3- (2 '-chlorophenoxy)prop.1.yl
A-
2 2l0 cycl p-oy -chiorophenoxy)prop1..yl A. 2211 cyclopropyl 3- (4 '-chiorophenoxy) prop-1-yl A.2212 cyclopropy. 3-(3'1,5',dichlorophenoxy)prop..1y1 A. 2213 cyclopropyl 3- (2 '-cyanophenoxy) prop-1-yl A. 2214 cyclopropyl 3- (3 '-cyanophenoxy) prop-1-yl A. 2215 cyclopropyl 3- (4 -cyanophenoxy) prop-1-yl A. 2216 cyclopropyl 3- (2 '-methylphenoxy)prop4...yl A. 2217 cyclopropyl 3- (3 '-methylphenoxy)prop-1.yl A.2218 cyclopropy. 3-(4 '-methylphenoxy)prop1..yl A. 2219 cyclopropyl 3- (2 -methoxyphenoxy) prop-1-yl A. 2220 cyclopropyl 3- -methoxyphenoxy) prop-1-yl A. 2221 cyclopropyl 3- (4 '-methoxyphenoxy)prop1..yl A. 2222 cyclopropyl 3- (2 '-trifluoromethylphenoxy) prop-1-yl A. 2223 cyclopropyl 3- (3 '-trifluoromethylphenoxy)prop.1.yl A. 2224 cyclopropyl 3- (4 '-trifluoromethylphenoxy) prop-1-yl A. 2225 cyclopropyl 4-phenoxybut-1-yl A. 2226 cyclopropyl 2-phenyleth-1-yl A.2227 cyclopropyl 2-(2 '-chlorophenyl)eth1..yl A. 2228 cyclopropy. 2- (3 '-chiorophenyl )eth-1-yl A.2229 cyclopropyl 2-(4 '-chlorophenyl)eth1.yl A.2230 cyclopropyl ,5 '-dichlorophenyl)eth1.yl A.2231 cyclopropyl 2-(2 '-cyanophenyl)eth-1.yl A.2232 cyclopropyl 2-(3 '-cyanophenyl)eth1.yl A.2233 cyclopropyl 4 -cyanophenyl)eth-1.yl A*2234 cyclopropyl 2-(2 -methylphenyl)ethl...yl A.2235 Icyclopropyl 2-(3 '-methylphenyl)eth1..yl A- 0'/ 0050/46043 170 No.R24 A. 2236 cyclopropyl 2-(4 '-methylphenyl)eth-1-yl A.2237 cyclopropyl 2- (2 '-methoxyphenyl)eth-1-yl A.2 23 8 cyclopropyl 2- (3 '-methoxyphenyl )eth-1-yl A.2239 cyclopropyl 2-(4 '-methoxyphenyl)eth-1-yl A.2240 cyclopropyl 2-(2 '-trifluoromethylphenyl)eth-1.yl A.2241 cyclopropyl 2-(3 '-trifluoromethylphenyl)eth-1.yl A.2242 cyclopropyl 2-(4 '-trifluoromethylphenyl)eth-1.yl A. 2243 cyclopropyl 3-phenylprop-1-yl A. 2244 cyclopropyl 3- -chiorophenyl )prop-1-yl A.2245 cyclopropyl 3-(3 '-chlorophenyl)prop-1-yl A.2246 cyclopropyl 3-(4 '-chlorophenyl)prop-1-yl A. 2247 cyclopropyl 3- (2 '-cyanophenyl )prop-1-yl A. 2248 cyclopropyl 3- (3 '-cyanophenyl )prop-1-yl A.2249 cyciopropyl 3-4'cyanophenyl)prop-i-yl A. 2250 cyc-lopropyl 3- (21'-trifluoromethyiphenyl )prop-1-yl A. 2251 cyclopropyl 4-phenylbut-1-yl A.2252 cyclopropyl 4-(4 '-chlorophenyl)but-1-yl A.2253 cyclopropyl 6-(4 '-chlorophenyl)hex-1-yl A. 2254 cyclopropyl 2-pyridylmethyl A. 2255 cyclopropyl 3-pyridylmethyl A. 2256 cyclopropy. 4-pyridylmethyl A. 2257 cyclopropyl 4-chloropyridin-2-ylmethyl A. 2258 cyclopropyl 5-chloropyridin-2-ylmethyl A. 2259 cyclopropyl 6-chloropyridin-2-ylmethyl A. 2260 cyclopropyl 5-chloropyridin-3-ylmethyl A. 2261 cyclopropyl 6-chloropyridin-3-ylmethyl A. 2262 cyclopropyl 2-chloropyridin-4-ylmethyl A. 2263 cyclopropyl 2-pyrimidinylmethyl A. 2264 cyclopropyl 4-chloropyrimidin-2-ylmethyl A. 2265 cyclopropy. 5-chloropyrimidin-2-ylmethyl A. 2266 cyclopropyl 2-chloropyrimidin-4-ylmethyl A. 2267 cyclopropyl 6-chloropyrimidin-4-ylmethyl A. 2268 cyclopropyl A. 2269 cyclopropyl 4-pyridazinylmethyl A. 2270 cyclopropyl 2-pyrazinylmethyl A. 2271 cycltopropyl 5-chloropyrazin-2-ylmethyl A. 2272 cyclopropyl 6-chloropyrazin-2-ylmethyl A. 2273 cyclopropyl 3-pyridazinylmethyl A. 2274 Icyclopropyl 6-chloropyridazin-3-ylmethyl
F
~K'Vr C~ 0050/46043 171 No.R24 A.2275 cyclopropyl 1,3, A.2276 cyclopropyl 2-furylmethyl A.2277 Icyclopropyl 3-furylmethyl A. 2278 cyclopropyl 4-bromofur-2-ylmethyl A. 2279 cyclopropyl 5-chlorofur-2-ylmethyl A. 2280 cyclopropyl 2-thienylmethyl A. 2281 cyclopropyl 3-thienylmethyl A. 2282 cyclopropyl 5-methylthien-3-ylmethy.
A. 2283 cyclopropyl 5-chlorothien-2-ylmethyl A. 2284 cyclopropyl 2-chlorothien-4-ylmethyl A. 2285 cyclopropyl 2-pyrrolylmethyl A. 2286 cyclopropyl 3-pyrrolylmethyl A. 2287 cyclopropyl 2-Oxazolylmethyl A. 2288 cyclopropyl 4-methyioxazol-2-ylmethyl A. 2289 cyclopropyl 5-methyloxazol-2-ylmethyl A. 2290 Icyclopropyl 4-chloro-oxazol-2-ylmethyl A. 2291 cyclopropyl 5-chloro-oxazol-2-ylmethyl A. 2292 cyclopropyl 4-oxazolylmethyl A. 2293 cyclopropyl 2-methyloxazol-4-ylmethyl A. 2294 cyclopropyl 5-methyloxazol-4-ylmethyl A. 2295 cyclopropyl 2-chloro-oxazol-4-ylmethyl A. 2296 cyclopropyl 5-chloro-oxazol-4-ylmethyl A. 2297 cyclopropy. A. 2298 cyclopropyl A. 2299 cyclopropyl A. 2300 cyclopropyl A. 2301 cyclopropyl A. 2302 cyclopropyl 2-thiazolylmethyl A. 2303 cyclopropyl 4-methylthiazol-2-ylmethyl A. 2304 cyclopropyl 5-methylthiazol-2-ylmethyl A. 2305 cyclopropyl 4-chlorothiazol-2-ylmethyl A. 2306 cyclopropyl 5-chlorothiazol-2-ylmethyl A. 2307 cyclopropyl 4-thiazolylmethyl A. 2308 cyclopropyl 2-methylthiazol-4-ylmethyl A. 2309 cyclopropyl 5-methylthiazol-4-ylmethyl A. 2310 cyclopropyl 2-chlorothiazol-4-ylmethyl A. 2311 cyclopropyl 5-chlorothiazol-4-ylmethyl A. 312cyclopropyl A.213cyclopropyl F 4/4 0 0050/46043 172 No. R 2
R
A. 2314 cyclopropyl A. 2315 cyclopropyl A. 2316 cyclopropy. A. 2317 cyclopropyl 3-isoxazolylmethyl A. 2318 cyclopropyl 4-methylisoxazol-3-ylmethyl A. 2319 Icyclopropyl 5-methylisoxazol-3-ylmethyl A.2320 cyclopropyl 4-chloro-isoxazol-3-ylmethyl A. 2321 cyclopropyl 5-chloro-isoxazol-3-ylmethyl A.2322 cyclopropyl 4-isoxazolylmethyl A. 2323 cyclopropyl 3-methylisoxazol-4-ylmethyl A. 2324 cyclopropyl 5-methylisoxazol-4-ylmethyl A. 2325 cyclopropyl 3-chloro-isoxazol-4-ylmethyl A. 2326 Icyclopropyl 5-chloro-isoxazol-4-ylmethyl A. 2327 icyclopropyl A. 2328 cyclopropyl A. 2329 cyclopropyl A.2330 cyclopropyl A.2331 cyclopropyl A.2332 cyclopropyl 3-isothiazolylmethyl A. 2333 cyclopropyl 4-methylisothiazol-3-ylmethyl A. 2334 cyclopropyl 5-methylisothiazol-3-ylmethyl A. 2335 cyclopropyl 4-chloroisothiazol-3-ylmethyl A. 2336 cyclopropyl 5-chloroisothiazol-3-ylmethyl A. 2337 cyclopropyl 4-isothiazolylmethyl A. 2338 cyclopropyl 3-methylisothiazol-4-ylmethyl A. 2339 cyclopropyl 5-methylisothiazol-4-ylmethyl A. 2340 cyclopropyl 3-chloroisothiazol-4-ylmethyl A.2341 cyclopropyl 5-chloroisothiazol-4-ylmethyl A. 2342 cyclopropyl A. 2343 cyclopropyl A. 2344 cyclopropyl A. 2345 cyclopropyl A. 2346 cyclopropyl A. 2347 cyclopropyl 4-imidazolylmethyl A. 2348 cyclopropyl 1-phenylpyrazol-3-ylmethyl A. 2349 cyclopropyl 1-methylimidazol-4-ylmethyl A.2350 cyclopropyl 1-phenyl-1,2 ,4-triazol-3-ylmethyl A.2351 cyclopropyl 1l,2, 4-oxadiazol-3.-ylmethyl A. 2352 Icyclopropyl 15-chloro-1, 2, 4-oxadiazol-3-ylmethyl 0050/46043 173 No. 2R A.2353 cyclopropyl 5-methyl-l,2,4-oxadiazol-3-ylmethyl A.2354 cyclopropyl 5-trifluoromethyl-1,2 ,4-oxadiazol-3-ylmethyl A.2355 cyclopropyl 1,3,4-oxadiazol-2-ylmethy.
A.2356 cyclopropyl 5-chloro-1,3,4-oxadiazol-2-ylmethyl A.2357 cyclopropyl 5-methyl-i, 3,4-oxadiazol-2-ylmethyl A.2358 cyclopropyl 5-methoxy-i, 3,4-oxadiazol-2-ylmethyl A.2359 cyclopropyl 1, 2,4-thiadiazol-3-ylmethyl A.2360 cyclopropyl 5-chloro-i,2,4-thiadiazol-3-ylmethyl A.2361 cyclopropyl 5-methyl-1,2 ,4-thiadiazol-3-ylmethyl A.2362 cyclopropyl 1, 3,4-thiadiazol-2-ylmethyl A.2363 cyclopropyl 5-chloro-i, 3,4-thiadiazol-2-ylmethyl A.2364 cyclopropyl 5-methyl-l,3,4-thiadiazol-2-ylmethyl 36 cylpropL,. 5 cyano-1 ,3 ,4-thiLadiazol-2l-ylmehL.
A.2366 cyclopropyl 2-(2 '-pyridinyloxy)eth-i-yl A. 2367 cyclopropyl 2- -pyridinyloxy) eth-i-yl A.2368 cyclopropyl 2-(4 '-pyridinyloxy)eth-i-yl A.2369 cyclopropyl 2-(2 '-pyrimidinyloxy)eth-1-yl A. 2370 cyclopropyl 2- (4 '-pyrimidinyloxy) eth-i-yl A.2371 cyclopropyl 2-(5 '-pyrimidinyloxy)eth-1-yl A.2372 cyclopropyl 2-(2 '-pyrazinyloxy)eth-i-yl A.2373 cyclopropyl 2-(2 '-pyridazinyloxy)eth-i-yl A.2374 cyclopropyl 2-(3 '-pyridazinyloxy)eth-i-yl A.2375 cyclopropyl 2-(11, 3',51-triazinyloxy)eth-1-yl A.2376 cyclopropyl 2-(5 '-methylisoxazol-3 '-yloxy)eth-l-yl A.2377 cyclopropyl 2-(5 '-chloro-isoxazol-3 '-yloxy)eth-1-yl A.2378 cyclopropyl 2-(2 '-methoxythiazol-4 '-yloxy)eth-l-yl A.2379 cyclopropyl 2-(4 '-chloro-oxazol-2 '-yloxy)eth-1-yl A.2380 cyclopropyl 2-(i'-phenyl-i'H-1',2',4'-triazol-3'-yleth-i-yl A.2381 cyclopropyl 1 -phenylpyrazol-3 '-yloxy)eth-1-yl A.2382 cyclopropyl C 6
H
A.2383 cyclopropyl 2-Cl-C 6
H
4 A.2384 cyclopropyl 3-Cl-C 6
H
4 A.2385 cyclopropyl 4-Cl-C 6
H
4 A.2386 cyclopropyl 2,3-C1 2
-C
6
H
3 A.2387 cyclopropyl 2,4-Cl 2
-C
6
H
3 A.2388 cyclopropyl 2,5-Cl 2
-C
6
H
3 A.2389 cyclopropyl 3,4-C1 2
-C
6
H
3 A.2390 Icyclopropyl 3, 5-C1 2
-C
6
H
3 0050/46043 174 No.R24 A.2391 cyclopropyl 4-CN-C 6
H
4 A.2392 cyclopropyl 2-N0 2
-C
6
H
4 A.2393 cyclopropyl 3-N0 2
-C
6
H
4 A.2394 cyclopropyl 4-N0 2
-C
6
H
4 A.2395 cyclopropyl 2,4-(N0 2 2
-C
6
H
3 A.2396 cyclopropyl 2-CH 3
-C
6
H
4 A.2397 cyclopropyl 3-CH 3
-C
6
H
4 A.2398 cyclopropyl 4-CH 3
-C
6
H
4 A.2399 cyclopropyl 2,3-(CH 3 2
-C
6
H
3 A.2400 cyclopropyl 2,4-(CH 3 2
-C
6
H
3 A.2401 cyclopropyl 2,5-(CH 3 2
-C
6
H
3 A.2402 cyclopropyl 2,6-(CH 3 2
-C
6
H
3 A.2403 cyclopropyl 2-C 6
H
5 -0 6
H
4 A.2404 cyciopropy. 3-C 6
H
5
-C
6
H
4 A.2405 cyclopropyl 4-C 6
H
5
-C
6
H
4 A.2406 cyclopropyl 3-OCH 3
-C
6
H
4 A.2407 cyclopropyl 4-OCH 3
-C
6
H
4 A.2408 cyclopropyl 3-acetyl-C 6
H
4 A.2409 cyclopropyl 4-acetyl-C 6
H
4 A. 2410 cyclopropyl 3-methoxycarbonyl-C 6
H
4 A. 2411 cyclopropyl 4-methoxycarbonyl-C 6
H
4 A.2412 cyclopropyl 3-0F 3
-C
6
H
4 A.2413 cyclopropyl 4-CF 3
-C
6
H
4 A.2414 cyclopropyl 2-naphthyl A. 2415 cyclopropyl 6-chloropyridazin3.yl A. 2416 cyclopropyl 5-chloropyrazin-2-yl A.2417 cyclopropyl quinolin-2-yl A. 2418 cyclopropyl 2, 5-dimethylpyrazin-3.yl A.2419 cyclopropyl pyrazin-2-yl A. 2420 cyclopropyl 3-chloropyrid-2-yl A. 2421 cyclopropyl 6-chloropyrid-2-yl A. 2422 cyclopropyl 4-trifluoromethyl, 6-chloropyrid-2-yl A. 2423 cyclopropyl 4 -trifluoromethylpyrid-2.yl A. 2424 cyclopropyl 6-trifluoromethylpyrid2.yl A. 2425 cyclopropyl 6-methoxypyrid-2-yl A. 2426 cyclopropyl 5-chloropyrid-2-y.
A.2427 cyclopropyl pyrid-2-yl A. 2428 cyclopropyl benzothiazo-2-yl.
A. 2429 cyclopropyl 7-chloroquinolin-4-yl 0050/ 46043 175 No.R24 A. 2430 cyclopropyl 3-nitropyrid-2-yl A.2431 cyclopropyl pyrrol-3-yl A.2432 cyclopropyl pyrrol-2-yl A.2433 cyclopropyl 2, 6-dioctylpyrid-4-yl A. 2434 cyclopropyl 5-nitropyrid-2-yl A.2435 cyclopropyl pyrid-4-yl A.2436 cyclopropyl pyrid-3-yl A.2437 cyclopropyl pyrimidin-2-yl A.2438 cyclopropyl pyrimidin-4-yl A. 2439 cyclopropyl quinazolin-4-yl A.2440 cyclopropyl 6-chloropyrimidin-4-yl A. 2441 cyclopropyl 6-methoxypyrimidin-4-yl A.2442 cyclopropyl 2,5, 6-trichloropyrimidin-4-yl A. 2443 cyclopropyl 2, 6-dimethylpyrimidin-4-yl A. 2444 cyclopropyl 2mty, 6-chloropyrimidin-4-yl A. 2445 cyclopropyl 2-methyl, 6-ethoxypyrimidin-4-yl A.2446 cyclopropyl 4,5, 6-trichloropyrimidin-2-yl A. 2447 cyclopropyl 4, 6-dimethoxypyrimidin-2-yl A. 2448 cyclopropyl 4, 6-dimethylpyrimidin-2-yl A. 2449 cyclopropyl 4, 6-dichloropyrimidin-2-yl A. 2450 cyclopropyl 4-methyl, 6-methoxypyrimidin-2-yl A. 2451 cyclopropyl 4-chloro, 6-methoxypyrimidin-2-yl A. 2452 cyclopropyl 6-chloroquinoxalin-2-yl A.2453 cyclopropyl 3,6-dichloro-1,2,4-triazin-5-yl A.2454 cyclopropyl 4-methoxy-1,3, 5-triazin-2-yl A.2455 cyclopropyl 4-ethoxy-1, 3, 5-triazin-2-yl A.2456 cyclopropyl 4,6-dichloro-1,3,5-triazin-2-yl A.2457 cyclopropyl 4-ethoxy, 6-chloro-1,3, 5-triazin-2-yl A.2458 cyclopropyl isoxazol-3-yl A.2459 cyclopropyl thien-2-yl A.2460 cyclopropyl fur-2-yl A. 2461 cyclopropyl A.2462 cyclopropyl (E)-1-chloropropen-3-yl A.2463 cyclopropyl '-chlorophenyl)but-2-en-1-yl A.2464 cyclopropyl propyn-3-yl A.2465 cyclopropyl methylcarbonyl A.2466 cyclopropyl ethylcarbonyl A. 2467 cyclopropyl n-propylcarbonyl A. 2468 Icyclopropyl i-propylcarbonyl 0050/46043 176 No. R 2
R
A. 2469 cyclopropyl n-butylcarbonyl A. 2470 cyclopropyl s-butylcarbonyl A. 2471 cyclopropyl i-butylcarbonyl A. 2472 cyclopropyl t-butylcarbonyl A. 2473 cyclopropyl n-pentylcarbonyl A. 2474 cyclopropyl i-pentylcarbonyl A. 2475 cyclopropyl neo-pentylcarbonyl A. 2476 cyclopropyl n-hexylcarbonyl A. 2477 cyclopropyl n-octylcarbonyl A. 2478 cyclopropyl 1-propenylcarbonyl A. 2479 cyclopropyl 2-penten-1-yl-carbonyl A.2480 cyclopropyl 2, 5-heptadien-1-yl-carbonyl A.2481 cyclopropyl benzoyl A. 2482 cyclopropyl 2-chlorobenzoyl A. 2483 cyclopropyl 3-chlorobenzoyl A.2484 cyclopropyl 4-chlorobenzoyl A.2485 cyclopropyl 2-cyanobenzoyl A.2486 cyclopropyl 3-cyanobenzoyl A.2487 cyclopropyl 4-cyanobenzoyl A. 2488 cyclopropyl 4-methoxybenzoyl A. 2489 cyclopropyl 2-pyridylcarbonyl A. 2490 cyclopropyl 3-pyridylcarbonyl A. 2491 cyclopropyl 4-pyridylcarbonyl A. 2492 cyclopropyl 2-pyrimidinylcarbonyl A. 2493 cyclopropyl 2-oxazolylcarbonyl A. 2494 cyclopropyl A.2495 cyclopropyl methylsulfonyl A.2496 cyclopropyl ethylsulfonyl A. 2497 cyclopropyl n-propylsulfonyl A. 2498 cyclopropyl i-propylsulfonyl A. 2499 cyclopropy. n-butylsulfonyl A. 2500 cyclopropy. t-butylsulfonyl A. 2501 cyclopropyl n-pentylsulfonyl A. 2502 cyclopropyl neo-pentylsulfonyl A. 2503 cyclopropyl n-hexylsulfonyl A. 2504 cyclopropyl n-octylsulfonyl A.2505 cyclopropyl phenylsulfonyl A. 2506 cyclopropyl 2-chiorophenylsulfonyl A 2507 Icyclopropy. 13-chlorophenylsulfonyl 0050/46043 177 No.R24 A. 2508 cyclopropyl 4-chlorophenylsulfonyl A. 2509 cyclopropyl 2-cyanophenylsulfonyl A. 2510 Icyclopropyl 3-cyanophenylsulfonyl A. 2511 cyclopropyl 4-cyanophenylsulfonyl A. 2512 cyclopropyl 2-pyridylsulfonyl A. 2513 cyclopropyl 3-pyridylsulfonyl A. 2514 cyclopropyl 4-pyridylsulfonyl A. 2515 cyclopropyl 2-pyrimidinylsulfonyl A. 2516 cyclopropyl 4-oxazolylsulfony.
A. 2517 cyclopropyl 5-chlorothiazol-2ylsulfonyl A. 2518 cyclopropyl 2-t-C 4
H
9
-C
6
H
4
-CH
2 A. 2519 cyclopropyl 3-t-C 4
H
9
-C
6
H
4
-CH
2 A. 2520 Icyclopropyl 4-t-C 4
H
9
-C
6
H
4
-CH
2 A.2521 cyciopropyl 2-(4 '-chlorothiazol-2 '-yloxy)eth-1-yi A.2522 cyciopropyl 1 -methylpyrazoi-4 '-yioxy)eth-1-yl A.2523 cyclopropyl 4-Br-C 6
H
4 A.2524 cyclopropyl 3, 5- (CH 3 2
-C
6
H
3 A.2525 cyciopropyl 4-C 2
H
5
-C
6
H
4 A. 2526 cyciopropyl 3-dimethylaminocarbonyl-C 6
H
4 A. 2527 cyclopropyl 4-dimethylaininocarbonyl-C 6
H
4 A. 2528 cyciopropyl 2-hydroxyprop-1-yl A. 2529 cyclopropyl 6-hydroxy-2-methylpyrimidin-4-ylmethyl A.2530 cyciopropyl [6-OH,2-CH(CH 3 2 -pyrimidin-4-ylJ-CH 2 A.2531 cyciopropyl 6-OH, 2-CH (CH 2 2 -pyrimidin-4-yl -CH 2 A.2532 cyciopropyl 5-(2'-furan)pent-1-yl A.2533 cyciopropyl 5-(2 '-N-methyipyrrol)pent-1-yl A.2534 cyciopropyl 2- (4-Cl-C 6
H
4 oxazol-4-y -CH 2 A. 2535 cyciopropyl 3-CF 3 -pyridin-2-yi A. 2536 cyclopropyl 5-CF 3 -pyridin-2-yl A.2537 cyclopropyl 6-(2'-thienyi)hex-1-yi A.2538 cyclopropyl (E)-3-chlorobut-2-en-1-yl A.2539 cyciopropyl (Z )-3-chlorobut-2-en-1-yi A.2540 cyciopropyl (E)-2-bromobut-2-en-1-yi A.2541 cyclopropyl (Z)-2-bromobut-2-en-1-yi A.2542 cyciopropyl (E)-1-chioroprop-1-en-3-yi A.2543 cyciopropyl (Z)-1-chioroprop-1-en-3-yi A.2544 cyciopropyl but-1-en-3-yl A.2545 cyciopropyl CH 2
CH
2 Br A.2546 cyclopropyl ICH 2
CH
2
CH
2 Br 0050/46043 178 No.R24 A.2547 cyclopropyl CH 2
CH
2
CH
2
CH
2 Br A. 2548 cyclopropyl 2-methoxyprop-1-yl A. 2549 cyclopropyl 2-ethoxyprop-1-yl A. 2550 cyclopropyl 2-isopropoxyprop-1-yl A.2551 cyclopropyl but-1-yn-3-yl A.2552 cyclopropyl but-1-yn-4-yl A.2553 cyclopropyl but-2-yn-4-yl A.2554 cyclopropyl pent-1-yn-4-yl A.2555 cyclopropyl pent-2-yn-4-yl A.2556 cyclopropyl A. 2557 cyclopropyl A. 2558 cyclopropyl E-2-chlorobut-2-en-1-yl A. 2559 cyclopropyl Z-2-chlorobut-2-en-1-yl A. 2560 cyciopropyl Z-1-chloroprop-1-en-3-yl A. 2561 cyciopropy. 2-methylprop-1-en-3-yl A. 2562 cyclopropyl 2-chloroprop-l-en-3-yl A. 2563 cyclopropyl 2-bromoprop-1-en-3-yl A.2564 cyclopropy. but-2-en-1-y.
A.2565 cyciopropyl but-3-en-1-yl A. 2566 cyciopropyl 1-iodoprop-1-yn-3-y.
A. 2567 cyciopropyl E-3-bromobut-2-en-1-yl A. 2568 cyciopropyl Z-3-bromobut-2-en-1-yl A.2569 n-C 3
H
7
H
A.2570 n-C 3
H
7
CH
3 A.2571 n-C 3
H
7
C
2
H
A.2572 n-C 3
H
7 n-C 3
H
7 A.2573 n-C 3
H
7 i-C 3
H
7 A.2574 n-C 3
H
7 cyclopropy.
A.2575 n-C 3
H
7 n-C 4 H9 A.2576 n-C 3
H
7
S-C
4 H9 A.2577 n-C 3
H
7 i-C 4 H9 A.2578 n-C 3
H
7 t-C 4
H
9 A.2579 n-C 3
H
7 n-C 5
H
11 A.2580 n-C 3
H
7 i-C 5 Hll A.2581 n-C 3
H
7 neO-C 5
H
11 A.2582 n-C 3
H
7 cyclopentyl A.2583 n-C 3
H
7 fl-C 6 Hl 3 A.2584 n-C 3
H
7 cyclohexyl A.2585 In-C 3
H
7 n-C 8 Hl 7
P
0050/46043 179 No.R24 A.2586 fl-C 3
H
7 CH 2
CH
2 Cl A.2587 n-C 3
H
7 (CH 2 4 Cl A.2588 n-C 3
H
7 CH 2
CN
A.2589 n-C 3
H
7 CH 2
CH
2
CN
A.2590 n-C 3
H
7 (CH 2 3
CN
A.2591 n-C 3
H
7 (CH 2 4
CN
A.2592 n-C 3
H
7 (CH 2 6
CN
A.2593 n-C 3
H
7 cyclohexylmethyl A. 2594 n-C 3
H
7 2-cyclohexyleth-1Ny A.2595 n-C 3
H
7 cyclopropylmethyl A. 2596 n-C 3
H
7 2 -cyclopropyeth1..yl A.2597 n-C 3
H
7 2-methoxyeth-.-yl A.2598 n-C 3
H
7 2-ethoxyeth-1-yl A.2599 n-C 3
H
7 2 -isopropoxyeth-1.yl A.2600 n-C 3
H
7 3-methoxyprop-1-yi A.2601 n-C 3
H
7 3-ethoxyprop-1-yl A. 2602 n-C 3
H
7 3 -isopropoxyprop1.y.
A.2603 n-C 3
H
7 4-methoxybut-1-yl A.2604 n-C 3
H
7 4 -isopropoxybut- l-yl A.2605 n-C 3
H
7 propen-3-yl A.2606 n-C 3
H
7 but-2-en-1-yl A.2607 n-C 3
H
7 3-methybut-2-en1..yl A.2608 n-C 3
H
7 2-vinyloxyeth-1-yl A.2609 n-C 3
H
7 allyloxyeth-1-yl A. 2610 n-C 3
H
7 2 -trifluoromethoxyeth-1..yl A. 2611 n-C 3
H
7 3 -trifluoromethoxyprop1.yl A. 2612 n-C 3
H
7 4-difluoromethoxybut.1.yl A. 2613 n-C 3
H
7 hydroxycarbonylmethyl A.2614 n-C 3
H
7 methoxycarbonylmethyl A.2615 n-C 3
H
7 aminocarbonylmethy.
A. 2616 n-C 3
H
7 N-methylaminocarbonylmethyl A. 2617 n-C 3
H
7 NN-dimethyamninocarbony...methyl A. 2618 n-C 3
H
7 2 -hydroxycarbonyleth1..yl A. 2619 n-C 3
H
7 2 -methoxycarbonyeth.1.yl A. 2620 ri-C 3
H
7 2-alninocarbonyleth1..yl A. 2621 n-C 3
H
7 2 -N-methylaminocarbonyleth1..yl A. 2622 n-C 3
H
7 2 -dimethylaminocarbonylh...1yl A.2623 n-C 3
H
7 2-aminoeth-1-yl A.2624 n-C 3
H
7 2 -aminoprop-1-yl 0050/ 46043 180 A-265 nC3.
A.2625 n-C 3
H
7 A.2627 lCH A.67n-C 3
H
7 A. 2628 n-C 3
H
7 A 2 629 n-C 3
H
7 A.2630 fl-C 3
H
7 A.2631 n-C 3
H
7 A.2632 n-C 3
H
7 A.2633 n-C 3
H
7 A.2634 n-C 3
H
7 A.2635 n-C 3
H
7 A.2636 n-C 3
H
7 A.2637 n-C 3
H
7 Al. 2 U3 8 f-'C 3 ii 7 4 -aminobut- 1-yl 3 -dimethylaminoprop.. -yl cyclopentyl 2 -methoxyininoprop.1 -yl 2 -methoxyiminoeth-.1 -yl 6 -aminocarbonylhex-1. -yl 3 -aminothiocarbonylprop-. -yl 2 -aminothiocarbonyleth.1 -yl aminothiocarbonylmethyl N-dimethylamino)but1..yl 2(methylthio )eth-1-yl 2-(methylsulfonyl )eth-1-yl A. 2639 n-C 3
H
1 I Loqu fl-C 3 ki 7 i Ai. Z041 fl-C 3
H-,
A.2642 n-C 3
H
7 4 -(methylsulfonyl)prop1..yl A.2643 n-C 3
H
7 benzyl A.2644 n-C 3
H
7 2-F-C 6
H
4
-CH
2 A.2645 n-C 3
H
7 3-F-C 6
H
4
-CH
2 A.2646 n-C 3
H
7 4-F-C 6
H
4
-CH
2 A.2647 n-C 3
H
7 2,3-F 2
-C
6
H
3
-CH
2 A.2648 n-C 3
H
7 2,4-F 2
-C
6
H
3
-CH
2 A.2649 n-C 3
H
7 2,5-F 2
-C
6
H
3
-CH
2 A.2650 n-C 3
H
7 2,6-F 2
-C
6
H
3
-CH
2 A.2651 n-C 3
H
7 3,4-F 2
-C
6
H
3
-CH
2 A.252n-C 3
H
7 3,5-F 2
-C
6
H
3
-CH
2 A.253n-C 3
H
7 2-C1-C 6
H
4
-CH
2 A.2654 n-C 3
H
7 3-C1-C 6
H
4
-CH
2 A.2655 n-C 3
H
7 4-Cl-C 6
H
4
-CH
2 A.2656 n-C 3
H
7 2,3-Cl 2
-C
6
H
3
-CH
2 A.2657 n-C 3
H
7 2,4-Cl 2
-C
6
H
3
-CH
2 A.2658 n-C 3
H
7 2 ,5-Cl 2
-C
6
H
3
-CH
2 A.2659 fl-C 3
H
7 2,6-Cl 2
-C
6
H
3
-CH
2 A.2660 n-C 3
H
7 3,4-Cl 2
-C
6
H
3
-CH
2 A.2661 fl-C 3
H
7 3,5-C 1 2
-C
6
H
3
-CH
2 A. 2662 n-C 3
H
7 2,3, 4-C1 3
-C
6
H
2
-CH
2 a Ir,,, nI%-3fl7 12, 3, 5-Cl3-C6H2-CH2 2,3, 5-C1 3
-C
6
H
2
-CH
2 0050/46043 181 No.R24 A.2664 n-C 3
H
7 2,3,6-C 3
-C
6
H
2
-CH
2 A.2665 n-C 3
H
7 2,4,5-Cl 3
-C
6
H
2
-CH
2 A.2666 n-C 3
H
7 2 ,4,6-C 3
-C
6
H
2
-CH
2 A.2667 n-C 3
H
7 3,4,5-C 3
-C
6
H
2
-CH
2 A.2668 n-C 3
H
7 2-Br-C 6
H
4
-CH
2 A.2669 n-C 3
H
7 3-Br-C 6
H
4
-CH
2 A.2670 n-C 3
H
7 4-Br-C 6
H
4
-CH
2 A.2671 n-C 3
H
7 2,3-Br 2
-C
6
H
3
-CH
2 A.2672 n-C 3
H
7 2,4-Br 2
-C
6
H
3
-CH
2 A.2673 n-C 3
H
7 2,5-Br 2
-C
6
H
3
-CH
2 A.2674 n-C 3
H
7 2,6-Br 2
-C
6
H
3
-CH
2 A.2675 n-C 3
H
7 3,4-Br 2
-C
6
H
3
-CH
2 A.2676 n-C 3
H
7 3,5-Br 2
-C
6
H
3
-CH
2 A.2677 9--C 3
H
7 2-F, 3-Cl-C 6
H
3
-CH
2 A.2678 n-C 3
H
7 2-F, 4-C1-C 6
H
3
-CH
2 A.2679 n-C 3
H
7 2-F, 5-Cl-C 6
H
3
-CH
2 A. 2680 n-C 3
H
7 2-F, 3-Br-C 6
H
3
-CH
2 A.2681 n-C 3
H
7 2-F, 4-Br-C 6
H
3
-CH
2 A. 2682 n-C 3
H
7 2-F, 5-Br-C 6
H
3
-CH
2 A. 2683 n-C 3
H
7 2-Cl, 3-Br-C 6
H
3
-CH
2 A. 2684 n-C 3
H
7 2-Cl, 4-Br-C 6
H
3
-CH
2 A.2685 n-C 3
H
7 2-Cl, 5-Br-C 6
H
3
-CH
2 A.2686 n-C 3
H
7 3-F, 4-Cl-C 6
H
3
-CH
2 A.2687 n-C 3
H
7 3-F, 5-Cl-C 6
H
3
-CH
2 A. 2688 n-C 3
H
7 3-F, 6-Cl-C 6
H
3
-CH
2 A. 2689 n-C 3
H
7 3-F, 4-Br-C 6
H
3
-CH
2 A.2690 n-C 3
H
7 3-F, 5-Br-C 6
H
3
-CH
2 A.2691 n-C 3
H
7 3-F, 6-Br-C 6
H
3
-CH
2 A.2692 n-C 3
H
7 3-Cl, 4-Br-C 6
H
3
-CH
2 A.2693 n-C 3
H
7 3-Cl, 5-Br-C 6
H
3
-CH
2 A. 2694 n-C 3
H
7 3-Cl, 6-Br-C 6
H
3
-CH
2 A.2695 n-C 3
H
7 4-F, 5-Cl-C 6
H
3
-CH
2 A.2696 n-C 3
H
7 4-F, 6-Cl-C 6
H
3
-CH
2 A. 2697 n-C 3
H
7 4-F, 5-Br-C 6
H
3
-CH
2 A.2698 n-C 3
H
7 4-F, 6-Br-C 6
H
3
-CH
2 A.2699 n-C 3
H
7 4-Cl, 5-Br-C 6
H
3
-CH
2 A.2700 n-C 3
H
7 5-F, 6-C1-C 6
H
3
-CH
2 A.2701 n-C 3
H
7 5-F, 6-Br-C 6
H
3
-CH
2 A.2702 n-C 3
H
7 15-Cl, 6-Br-C 6
H
3
-CH
2 T C 0050/46043 No.R24 A.2703 n-C 3
H
7 3-Br, 4-Cl, 5-Br-C 6
H
2
-CH
2 A.2704 fl-C 3
H
7 2-CN-C 6
H
4
-CH
2 A.2705 n-C 3
H
7 3-CN-C 6
H
4
-CH
2 A.2706 n-C 3
H
7 4-CN-C 6
H
4
-CH
2 A.2707
Y-C
3
H
7 2-N0 2
-C
6
H
4
-CH
2 A.2708 n-C 3
H
7 3-N0 2
-C
6
H
4
-CH
2 A.2709 n-C 3
H
7 4-N0 2
-C
6
H
4
-CH
2 A.2710 fl-C 3
H
7 2-CH 3
-C
6
H
4
-CH
2 A.2711 fl-C 3
H
7 3-CH 3
-C
6
H
4
-CH
2 A.2712 fl-C 3
H
7 4-CH 3
-C
6
H
4
-CH
2 A.2713 n-C 3
H
7 2 ,3-(CH 3 2
-C
6
H
3
.CH
2 A.2714 n-C 3
H
7 2,4-(CH 3 2
-C
6
H
3
.CH
2 A.2715 fl-C 3
H
7 2 ,5-(CH 3 2
-C
6
H
3
-CH
2 A.2716 n-C 3
H
7 2,6- (CH 3 2
-C
6
H
3
-CH
2 A.2717 n-C 3
H
7 3,4-(CH 3 2
-C
6
H
3
-CH
2 A.2718 n-C 3
H
7 3,5-(CH 3 2
-C
6
H
3
-CH
2 A.2719 n-C 3
H
7 2-C 2
H
5
-C
6
H
4
-CH
2 A.2720 n-C 3
H
7 3-C 2
H
5
-C
6
H
4
-CH
2 A.2721 n-C 3
H
7 4-C 2
H
5
-C
6
H
4
-CH
2 A.2722 n-C 3
H
7 2-i-C 3
H
7
-C
6
H
4
-CH
2 A. 2723 n-C 3
H
7 3-i-C3H 7
-C
6
H
4
-CH
2 A. 2724 n-C 3
H
7 4-i-C 3
H
7
-C
6
H
4
-CH
2 A.2725 n-C 3
H
7 2 -cyc lohexyl-C 6
H
4
-CH
2 A. 2726 n-C 3
H
7 3 -cyclohexyl-C 6
H
4
.CH
2 A. 2727 n-C 3
H
7 4 -cyclohexyl-C 6
H
4
-CH
2 A.2728 n-C 3
H
7 2 -viflyl-C 6
H
4
-CH
2 A.2729 n-C 3
H
7 3 -viflyl-C 6
H
4
-CH
2 A.2730 fl-C 3
H
7 4 -vlflyl-C 6
H
4
-CH
2 A.2731 n-C 3
H
7 2-allYl-C 6
H
4
-CH
2 A.2732 n-C 3
H
7 3-allYl-C 6
H
4
-CH
2 A.2733 n-C 3
H
7 4-allYl-C 6
H
4
-CH
2 A.2734 n-C 3
H
7 2-C 6
H
5
-C
6
H
4
-CH
2 A.2735 n-C 3
H
7 3-C 6
H
5
-C
6
H
4
-CH
2 A.2736 n-C 3
H
7 4-C 6
H
5
-C
6
H
4
-CH
2 A. 2737 n-C 3
H
7 3-CH 3 5-t-C 4
H
9
-C
6
H
3
-CH
2 A.2738 n-C 3
H
7 2-OH-C 6
H
4
-CH
2 A.2739 n-C 3
H
7 3-OH-C 6
H
4
-CH
2 A.2740 n-C 3
H
7 4-OH-C 6 11 4
-CH
2 [A.2741 n-C 3
H
7 2-OCH 3
-C
6
H
4
-CH
2
T
'HA
0050/ 46043 183 No.R24 A.2742 n-C 3
H
7 3-OCH 3
-C
6
H
4
-CH
2 A.2743 n-C 3
H
7 4-OCH 3
-C
6
H
4
-CH
2 A.2744 n-C 3
H
7 2,3-(CH 3 2
-C
6
H
3
-CH
2 A.2745 n-C 3
H
7 2,4-(OCH 3 2
-C
6
H
3
-CH
2 A.2746 n-C 3
H
7 2,5-(OCH 3 2
-C
6
H
3
-CH
2 A.2747 n-C 3
H
7 3,4-(OCH 3 2
-C
6
H
3
-CH
2 A.2748 n-C 3
H
7 3, 5- (OCH 3 2
-C
6
H
3
-CH
2 A.2749 n-C 3
H
7 3,4,5-(OCH 3 3
-C
6
H
2
-CH
2 A.2750 n-C 3
H
7 2-0C 2
H
5
-C
6
H
4
-CH
2 A.2751 n-C 3
H
7 3-0C 2
H
5
-C
6
H
4
-CH
2 A.2752 n-C 3
H
7 4-0C 2
H
5
-C
6
H
4
-CH
2 A.2753 n-C 3
H
7 2-O-(n-C 3
H
7
)-C
6
H
4
-CH
2 A. 2754 n-C 3
H
7 3-0- (n-C 3
H
7
-C
6
H
4
-CH
2 A.2755 n-C 3
H
7 4-0-(n-C 3
H
7
)-C
6
H
4
-CH
2 A. 2756 n-C 3
H
7 2-0- (i-C 3
H
7
)-C
6
H
4
-CH
2 A. 2757 n-C 3
H
7 3-0- (i-C 3
H
7
)-C
6
H
4
-CH
2 A. 2758 n-C 3
H
7 4-0- i-C 3
H
7
-C
6
H
4
-CH
2 A. 2759 n-C 3
H
7 4-0- (n-C 4
H
9
)-C
6
H
4
-CH
2 A. 2760 n-C 3
H
7 3-0- (t-C 4
H
9
-C
6
H
4
-CH
2 A. 2761 n-C 3
H
7 4-0- (n-C 6 Hl 3
-C
6
H
4
-CH
2 A.2762 n-C 3
H
7 2-0-allYl-C 6
H
4
-CH
2 A.2763 n-C 3
H
7 3-0-allYl-C 6 1 4
-CH
2 A.2764 n-C 3
H
7 4-0-allYl-C 6
H
4
-CH
2 A.2765 n-C 3
H
7 2-CF 3
-C
6
H
4
-CH
2 A.2766 n-C 3
H
7 3-CF 3
-C
6
H
4
-CH
2 A.2767 n-C 3
H
7 4-CF 3
-C
6
H
4
-CH
2 A.2768 n-C 3
H
7 2-acetyl-C 6
H
4
-CH
2 A.2769 n-C 3
H
7 3-acetyl-C 6
H
4
-CH
2 A.2770 n-C 3
H
7 4-acetyl-C 6
H
4
-CH
2 A. 2771 n-C 3
H
7 2-methoxycarbonyl-C 6
H
4
-CH
2 A. 2772 n-C 3
H
7 3-methoxycarbonyl-C 6
H
4
-CH
2 A. 2773 n-C 3
H
7 4-methoxycarbonyl-C 6
H
4
-CH
2 A. 2774 n-C 3
H
7 2-aminocarbonyl-C 6
H
4
-CH
2 A. 2775 n-C 3
H
7 3-aminocarbonyl-C 6
H
4
-CH
2 A. 2776 n-C 3
H
7 4-aminocarbonyl-C 6
H
4
-CH
2 A. 2777 n-C 3
H
7 2-dimethylaminocarbonyl-C 6
H
4
-CH
2 A. 2778 n-C 3
H
7 3-dimethylaminocarbonyl-C 6
H
4
-CH
2 A. 2779 n-C 3
H
7 14-dimethylaminocarbonyl-C 6
H
4
-CH
2 A.2780 in-C 3
H
7 12-(N-methylaminocarbonyl)
-C
6
H
4
-CH
2 I 0050/46043 184 No.R24 A. 2781 n-C 3
H
7 3- (N-methylaminocarbonyl)
-C
6
H
4
-CH
2 A.2782 n-C 3
H
7 4- (N-methylaminocarbonyl)
-C
6
H
4
-CH
2 A. 2783 n-C 3
H
7 2-H 2
N-C
6
H
4
-CH
2 A. 2784 n-C 3
H
7 3-H 2
N-C
6
H
4
-CH
2 A.2785 n-C 3
H
7 4-H 2
N-C
6
H
4
-CH
2 A. 2786 n-C 3
H
7 2-aminothiocarbonyl-C 6
H
4
-CH
2 A. 2787 n-C 3
H
7 3-aininothiocarbonyl-C 6
H
4
-CH
2 A. 2788 n-C 3
H
7 4-aminothiocarbonyl-C 6
H
4
-CH
2 A. 2789 n-C 3
H
7 2-methoxyiminomethyl-C 6
H
4
-CH
2 A. 2790 n-C 3
H
7 3-methoxyiminomethyl-C 6
H
4
-CH
2 A. 2791 n-C 3
H
7 4-methoxyiminomethyl-C 6
H
4
-CH
2 A.2792 n-C 3
H
7 2-formyl-C 6
H
4
-CH
2 A.2793 n-C 3
H
7 3-formyl-C 6
H
4
-CH
2 A.Z794 n-C 3
H
7 4-tormyl-C 6
H
4
-CH
2 A.2795 n-C 3
H
7 2-(1 1 '-methoxyiminoeth-
-C
6
H
4
-CH
2 A.2796 n-C 3
H
7 1 -methoxyiminoeth-1 '-Yl)-C 6
H
4
-CH
2 A.2797 n-C 3
H
7 1 -methoxyiminoeth-l1'-Yl)-C 6
H
4
-CH
2 A.2798 n-C 3
H
7 2-SCH 3
-C
6
H
4
-CH
2 A.2799 n-C 3
H
7 3-SCH 3
-C
6
H
4
-CH
2 A.2800 n-C 3
H
7 4-SCH 3
-C
6
H
4
-CH
2 A.2801 n-C 3
H
7 2-SO 2
CH
3
-C
6
H
4
-CH
2 A. 2802 n-C 3
H
7 3-SQ 2
CH
3
-C
6
H
4
-CH
2 A. 2803 n-0 3
H
7 4-SO 2
CH
3
-C
6
H
4
-CH
2 A.2804 n-C 3
H
7 2-OCF 3
-C
6
H
4
-CH
2 A.2805 n-C 3
H
7 3-OCF 3
-C
6
H
4
-CH
2 A.2806 n-C 3
H
7 4-OCF 3
-C
6
H
4
-CH
2 A.2807 n-C 3
H
7 2-OCHF 2
-C
6
H
4
-CH
2 A.2808 n-C 3
H
7 3-OCHF 2
-C
6
H
4
-CH
2 A.2809 n-C 3
H
7 4-OCHF 2
-C
6
H
4
-CH
2 A. 2810 rI-C 3
H
7 3-CF 3 4-OCF 3
-C
6
H
3
-CH
2 A.2811 n-C 3
H
7 1-naphthyl-CH 2 A.2812 n-C 3
H
7 2-naphthyl-CH 2 A.2813 n-C 3
H
7 2-phenoxyeth-1-yl A.2814 n-C 3
H
7 2-(2'-chlorophenoxy)eth-1-yl A.2815 n-C 3
H
7 2-(3 '-chlorophenoxy)eth-1-yl A.2816 n-C 3
H
7 2-(4 '-chlorophenoxy)eth-1-yl A.2817 n-C 3
H
7 ,5'-dichlorophenoxy)eth-1-yl A.2818 n-C 3
H
7 2-(2'-cyanophenoxy)eth-1-yl A.2819 In-C 3
H
7 12-(3'-cyanophenoxy)eth-1-yl 0050/46043 185 No.R24 A.2820 n-C 3
H
7 2 4 '-cyanophenoxy)eth-l-yl A.2821 n-C 3
H
7 2 2 '-methylphenoxy)eth.1-yl A.2822 n-C 3
H
7 2 31 -methylphenoxy)eth...-yl A.2823 fl-C 3
H
7 2 4 '-methylphenoxy)eth-1-yl A.2824 n-C 3
H
7 2 31 t-butylphenoxy)eth-1.yl A.2825 fl-C 3
H
7 2-(4 '-t-butylphenoxy)eth-1-yl A .2 82 6 n-C 3
H
7 2-(2 '-nitrophenoxy)eth-1-yl A.2827 n-C 3
H
7 2 -(3'-nitrophenoxy)eth-1-yl A.2828 n-C 3
H
7 2-(4 '-nitrophenoxy)eth-1-yl A.2829 n-C 3
H
7 2-(2 '-methoxyphenoxy)eth-1-yl A.2830 n-C 3
H
7 2-(3 '-methoxyphenoxy)eth-1-yl A.2831 n-C 3
H
7 2-(4 '-methoxyphenoxy)eth-1-yl A.2832 n-C 3
H
7 2- (2 '-trifluoromethylphenoxy)eth1.yl A. 2 833" n-C 3
H
7 2-(3 '-trifluoromethylphenoxy)eth1.y.
A.2834 n-C 3
H
7 2-(4 '-trifluoromethylphenoxy)eth1..yl A.2835 n-C 3
H
7 2-(2 '-acetylphenoxy)eth-1-yl A.2836 n-C 3
H
7 2-(3 '-acetylphenoxy)eth-1-yl A.2837 n-C 3
H
7 2-(4 '-acetylphenoxy)eth-1-yl A.2838 n-C 3
H
7 2-(2 '-methoxycarbonyl)eth-1-yl A.2839 n-C 3
H
7 2-(3 '-methoxycarbonyl)eth-1-yl A.2840 n-C 3
H
7 2-(4 '-methoxycarbonyl)eth-1-yl A.2841 n-C 3
H
7 2-(2 '-dimethylaminocarbony)eth1.y1 A. 2842 n-C 3
H
7 2- -dimethylaminocarbonyl )eth-1-yl A. 2843 n-C 3
H
7 2- (4 '-dimethylaxainocarbonyl )eth-1-yl A.2844 n-C 3
H
7 2- -aminothiocarbonyl )eth-1-yl A.2845 n-C 3
H
7 2-(3 '-aminothiocarbonyl)eth-1.yl A.2846 n-C 3
H
7 2-(4 -aminothiocarbonyl)eth-1.yl A.2847 n-C 3
H
7 2-(2 '-methylsulfonyl)eth-1-yl A.2848 n-C 3
H
7 2-(3'-methylsulfonyl)eth-1yl A.2849 n-C 3
H
7 2- -methylsulfonyl )eth-1-yl A.2850 n-C 3
H
7 3-phenoxyprop-1-yl A.2851 n-0 3
H
7 3-(2 '-chlorophenoxy)prop-1-yl A.2852 n-C 3
H
7 3-(3 '-chlorophenoxy)prop-1-y.
A.2853 n-C 3
H
7 3-(4 '-chlorophenoxy)prop-1-yl A.2854 n-C 3
H
7 ,dichlorophenoxy)prop.1-yl A.2855 n-C 3
H
7 3-(2'-cyanophenoxy)prop-1-yl A.2856 n-C 3
H
7 3-(3 '-cyanophenoxy)prop-1-yl A.2857 n-C 3
H
7 3-(4'-cyanophenoxy)prop-1-yl [A-2-858 In-C 3
H
7 3-(2 '-methylphenoxy)prop-1-yl 0050/46043 186 No.R24 A.2859 n-C 3
H
7 3-(3 '-methylphenoxy)prop-1-yl A.2860 n-C 3
H
7 3-(4 '-methylphenoxy)prop-1-yl A.2861 n-C 3
H
7 3-(2 '-methoxyphenoxy)prop-1-yl A.2862 n-C 3
H
7 3-(3 '-methoxyphenoxy)prop-1-yl A.2863 n-C 3
H
7 3-(4 '-methoxyphenoxy)prop-1-yl A.2864 In-C 3
H
7 3-(2 '-trifluoromethylphenoxy)prop-1-yl A.2865 n-C 3
H
7 3-(3 '-trifluoromethylphenoxy)prop-1-yl A.2866 n-C 3
H
7 3-(4 '-trifluoromethylphenoxy)prop-1-yl A.2867 n-C 3
H
7 4-phenoxybut-1-yl A.2868 n-C 3
H
7 2-phenyleth-1-yl A.2869 n-C 3
H
7 2-(2'-chlorophenyl)eth-1-yl A.2870 n-C 3
H
7 2-(3'-chlorophenyl)eth-1-yl A.2871 n-C 3
H
7 2-(4'-chlorophenyl)eth-1-yl A.2872 n-C 3
H
7 2-(3',5'-dichlorophenyl)eth-1-yl A.2873 n-C 3
H
7 2-(2'-cyanophenyl)eth-1-yl A.2874 n-C 3
H
7 2-(3'-cyanophenyl)eth-1-yl A.2875 n-C 3
H
7 2-(4'-cyanophenyl)eth-1-yl A.2876 n-C 3
H
7 2-(2'-inethylphenyl)eth-1-yl A.2877 n-C 3
H
7 2-(3 '-methylphenyl)eth-1-yl A.2878 n-C 3
H
7 2-(4'-methylphenyl)eth-1-yl A. 2879 n-C 3
H
7 2-(2 '-methoxyphenyl)eth-1-yl A.2880 n-C 3
H
7 2-(3'-methoxyphenyl)eth-1-yl A. 2881 n-C 3
H
7 2-(4 '-methoxyphenyl)eth-1-yl A.2882 n-C 3
H
7 2-(2 '-trifluoromethylphenyl)eth-1-yl A.2883 n-C 3
H
7 2-(3 '-trifluoromethylphenyl)eth-1-yl A.2884 n-C 3
H
7 2-(4 '-trifluoromethylphenyl)eth-1-yl A.2885 n-C 3
H
7 3-phenylprop-1-yl A.2886 n-C 3
H
7 3-(2 '-chlorophenyl)prop-1-yl A.2887 n-C 3
H
7 3-(3 '-chlorophenyl)prop-1-yl A.2888 n-C 3
H
7 3-(4'-chlorophenyl)prop-1-yl A.2889 n-C 3
H
7 3-(2'-cyanophenyl)prop-1-yl A.2890 n-C 3
H
7 3-(3 '-cyanophenyl)prop-1-yl A.2891 n-C 3
H
7 3-(4'--cyanophenyl)prop-1-yl A.2892 n-C 3
H
7 3-(2 '-trifluoromethylphenyl)prop-1-yl A.2893 n-C 3
H
7 4-phenylbut-1-yl A.2894 n-C 3
H
7 4-(4'-chlorophenyl)but-1-yl A.2895 n-C 3
H
7 6-(4'-chlorophenyl)hex-1-yl A.2896 n-C 3
H
7 2-pyridylmethyl A.2897 n-C 3
H
7 13-pyridylmethyl 0050/46043 187 No.R24 A. 2898 n-C 3
H
7 4-pyridylmethyl A. 2899 n--C 3
H
7 4 -chloropyridin-2-ylnethyl A. 2900 n-C 3
H
7 5-chloropyridin-2-ylmethyl A.2901 n-C 3
H
7 6-chloropyridin-2 -ylmethyl A. 2902 n-C 3
H
7 5-chloropyridin-3-ylmethyl A. 2903 n-C 3
H
7 6 -chloropyridin-3-ylmethyl A. 2904 n-C 3
H
7 2 -chloropyridin-4-ylmethyl A.2905 n-C 3
H
7 2 -pyrimidinylmethyl A.2906 n-C 3
H
1 4 -chloropyrimidin-2 -ylmethyl A. 2907 n-C 3
H
7 S-chloropyrimidin2..ylmethyl A. 2908 n-C 3
H
7 2 -chloropyrimidin-4.ylmethyl A. 2909 n-C 3
H
7 6 -chloropyrimidin4..ylmethyl A. 2910 n-C 3
H
7 2 A.2911 n.-C 3
H
7 4 -pyridazinylmethy.
A.2912 n-C 3
H
7 2 -pyrazinylmethyl A. 2913 n-C 3
H
7 5-chloropyrazin-2-ylmethyl A. 2914 n-C 3
H
7 6 -chloropyrazin-2-ylmethyl A.2915 n-C 3
H
7 3-pyridazinylmethyl A. 2916 n-C 3
H
7 6 -chloropyridazin-3-ylmethyl A.2917 n-C 3
H
7 l, 3 A.2918 n-C 3
H
7 2-furylmethyl A.2919 n-C 3
H
7 3-furylmethyl A. 2920 n-C 3
H
7 4-bromofur-2-ylmethyl A.2921 n-C 3
H
7 5-chlorofur-2 -ylmethyl A.2922 n-C 3
H
7 2-thienylmethyl A.2923 n-C 3
H
7 3-thienylmethyl A. 2924 n-C 3
H
7 5-methylthien-3-ylmethyl A. 2925 n-C 3
H
7 5-chlorothien-2-ylmethyl A.2926 n-C 3
H
7 2 -chlorothien-4 -ylmethy.
A.2927 n-C 3
H
7 2 -pyrrolylmethyl A.2928 n-C 3
H
7 3-pyrrolylmethyl A.2929 n-C 3
H
7 2-oxazolylmethyl A.2930 n-C 3
H
7 4-methyloxazol-2 -ylmethyl A. 2931 n-C 3
H
7 S-methyloxazol-2-ylmethyl A. 2932 n-C 3
H
7 4 -chloro-oxazol-2-ylmethyl A. 2933 n-C 3
H
7 5-chloro-oxazol-2-ylmethyl A.2934 n-C 3
H
7 4-oxazolylmethyl A. 2935 n-C 3
H
7 2 -methyloxazol-4-ylmethyl H1I. A.2936 In-C 3
H
7 5-methyloxazol-4-ylmethyl 0050/46043 188 No.R24 A. 2937 n-C 3
H
7 2 -chloro-oxazol-4-ylmethyl A. 2938 n-C 3
H
7 5-chloro-oxazol-4-ylmethyl A.2939 n-C 3
H
7 A. 2940 n-C 3
H
7 2 A.2941 n-C 3
H
7 4 A. 2942 n-C 3
H
7 2 A. 2943 n-C 3
H
7 4 A.2944 n-C 3
H
7 2-thiazolylmethyl A. 2945 n-C 3
H
7 4-methylthiazol-2-ylmethy.
A. 2946 n-C 3
H
7 5-methylthiazol-2-ylmethyl A. 2947 n-C 3 1 7 4 -chlorothiazol-2-ylmethyl A. 2948 n-C 3
H
7 5-chlorothiazol-2-ylmethyl A.249n-C 3
H
7 4-thiazolylmethy.
A 250I-CH 2 -methylthiazol- 4-ylmethyl A. 2951 n-C 3
H
7 5-methylthiazol-4-ylmethyl A. 2952 n-C 3
H
7 2-chlorothiazol-4-ylmethyl A.2953 n-C 3
H
7 5-chlorothiazol-4-ylmethyl A.2954 n-C 3
H
7 A.2955 n-C 3
H
7 2 A. 2956 n-C 3
H
7 A. 2957 n-C 3
H
7 2 A.2958 n-C 3
H
7 A.2959 n-C 3
H
7 3-isoxazolylmethyl A. 2960 n-C 3
H
7 4-methylisoxazol-3-ylmethyl A.2961 n-C 3
H
7 5-methylisoxazol- 3-ylmethyl A. 2962 n-C 3
H
7 4 -chloro--isoxazol-3..ylmethyl A. 2963 n-C 3
H
7 5-chloro-isoxazol-3..ylmethyl A.2964 n-C 3
H
7 4-isoxazolylmethyl A.2965 n-C 3
H
7 3 -methylisoxazo1-4-ylmethy1 A. 2966 n-C 3
H
7 5-methylisoxazol-4-ylmethyl A. 2967 n-C 3
H
7 3 -chloro-isoxazol-4-ylmethyl A. 2968 n-C 3
H
7 S-chloro-isoxazol-4-ylmethyl A.2969 n-C 3
H
7 A.2970 n-C 3 H 7 3 -methylisoxazol-5 -ylmethyl A. 2971 n-C 3
H
7 A. 2972 n-C 3
H
7 A. 2973 fl-C 3
H
7 4 A. 2974 n-C 3
H
7 3-isothiazolylmethyl A.2975 n-C 3
H
7 4 -methylisothiazol-3-ylmethyl 4- 0050/46043 189 No.R24 A. 2976 n-C 3
H
7 5-methyiisothiazol.3.ylmethyl A. 2977 n-C 3
H
7 4 -chloroisothiazol-3.ylmethyl A. 2978 n-C 3
H
7 5-chloroisothiazol-3-ylmethyl A. 2979 n-C 3
H
7 4-isothiazolylmethyl A. 2980 n-C 3
H
7 3-methylisothiazol-4-ylmethyl A. 2981 n-C 3
H
7 5-methylisothiazol-4-ylmethyl A. 2982 n-C 3
H
7 3-chloroisothiazol-4-ylmethyl A. 2983 n-C 3
H
7 5-chloroisothiazol-4-ylmethyl A. 2984 n-C 3
H
7 A. 2985 n-C 3
H
7 A. 2986 n-C 3
H
7 A. 2987 n-C 3
H
7 A. 2988 n-C 3
H
7 A.2989 n-C 3
H
7 4-imidazolylmethyl A. 2990 In-C 3
H
7 1-phenylpyrazol-3-ylmethyl A. 2991 n-C 3
H
7 1-methyiimidazol-4-ylmethy.
A.2992 n-C 3
H
7 i-phenyl-i,2 ,4-triazol-3-ylmethyl A. 2993 n-C 3
H
7 1,2, 4-oxadiazol-3-ylmethy.
A.2994 n-C 3
H
7 5-chioro-1,2,4-oxadiazo1-3-ylmethyl A.2995 n-C 3
H
7 5-methyl-1,2, 4-oxadiazol-3-ylmethyl A.2996 n-C 3
H
7 5-trifluoromethyl-1,2,4-oxadiazol.3yl- _______methyl A.2997 rI-C 3
H
7 l,3,4-oxadiazol-2-ylmethy.
A.2998 n-C 3
H
7 5-chioro-1, 3,4-oxadiazoi-2-ylmethyl A.2999 n-C 3
H
7 5-methyl-i, 3,4-oxadiazol-2-ylmethyi A.3000 n-C 3
H
7 5-methoxy-1,3,4-oxadiazol-2-ylmethyl A.3001 n-C 3
H
7 1,2 ,4-thiadiazol-3-ymethy.
A.3002 n-C 3
H
7 5-chloro-1,2,4-thiadiazol-3-ylmethyl A.3003 In-C 3
H
7 5-methyi-1,2,4-thiadiazol-3-ylmethyl A.3004 n-C 3
H
7 1,3, 4-thiadiazol-2-ylmethyl A.3005 n-C 3
H
7 5-chloro-1, 3,4-thiadiazol-2-ylmethyl A.3006 n-C 3
H
7 5-methyl-i, 3,4-thiadiazol-2-ylmethyl A.3007 n-C 3
H
7 5-cyano-l, 3, 4-thiadiazol-2-ylmethyl A.3008 n-C 3
H
7 2-(2 '-pyridinyloxy)eth-1-yl A.3009 n-C 3
H
7 2-(3'-pyridinyloxy)eth-1-yl A.3010 n-C 3
H
7 2-(4'-pyridinyloxy)eth-1-yl A.3011 n-C 3
H
7 2-(2'-pyrimidinyloxy)eth-i-yl A.3012 n-C 3
H
7 2-(4 '-pyrimidinyloxy)eth-l-yl A.3013 in-C 3
H
7 2-(5 '-pyrimidinyloxy)eth-l-yl 0050/46043 190 No.R24 A.3014 n-C 3
H
7 2 2 '-pyrazinyloxy)eth-.-yl A.3015 fl-C 3
H
7 2 -(2'-pyridazinyloxy)eth1.yl A.3016 n-C 3
H
7 2-(3 '-pyridazinyloxy)eth-1-yl A.3017 n-C 3
H
7 2 -(l'i 3 1 5'-triazinyloxy)eth.1-yl A.3018 n-C 3
H
7 2- -methylisoxazol-3' -yloxy)eth-1-yl A. 3019 n-C 3
H
7 2-(5 '-chloro-isoxazol-3 '-yloxy)eth-1-yl A.3020 n-C 3 ii 7 2-(2 '-methoxythiazol-.4 '-yloxy)eth-1-yl A.3021 n-C 3 Ii 7 2-(4 '-chloro-oxazol.2 -yloxy)eth-1-yl A.3022 n-C 3
H
7 2-(1'-phenyl-I 4 -triazol-3'-yleth- l-y.
A.3023 n-C 3
H
7 1 -phenylpyrazol-3 '-yloxy)eth-1-yl A.3024 n-C 3
H
7 C 6
H.
A.325n-C 3
H
7 2-Cl-C 6
H
4 A.326n-C 3
H
7 i3-C1-C 6
H
4 A.3027 n-C 3
H
7 4-Cl-C 6
H
4 A.3028 YI-C 3
H
7 2,3-Cl 2
-C
6
H
3 A.3029 n-C 3
H
7 2,4-Cl 2
-C
6
H
3 A.3030 n-C 3
H
7 2,5-C1 2
-C
6
H
3 A.3031 n-C 3
H
7 3,4-Cl 2
-C
6
H
3 A.3032 n-C 3
H
7 3,5-Cl 2
-C
6
H
3 A.3033 n-C 3
H
7 4-CN-C 6
H
4 A.3034 n-C 3
H
7 2-N0 2
-C
6
H
4 A.3035 n-C 3
H
7 3-N0 2
-C
6
H
4 A.3036 n-C 3
H
7 4-N0 2
-C
6
H
4 A.3037 n-C 3
H
7 2, 4- (N0 2 2
-C
6
H
3 A.3038 n-C 3
H
7 2-CH 3
-C
6
H
4 A.3039 n-C 3
H
7 3-CH 3
-C
6
H
4 A.3040 n-C 3
H
7 4-CH 3
-C
6
H
4 A.3041 n-C 3
H
7 2,3-(CH 3 2
-C
6
H
3 A.3042 n-C 3
H
7 2,4-(CH 3 2
-C
6
H
3 A.3043 n-C 3
H
7 2,5-(CH 3 2
-C
6
H
3 A.3044 n-C 3
H
7 2,6-(CH 3 2
-C
6
H
3 A.3045 n-C 3
H
7 2-C 6
H
5
-C
6
H
4 A.3046 n-C 3
H
7 3-C 6
H
5
-C
6
H
4 A.3047 n-C 3
H
7 4-C 6
H
5
-C
6
H
4 A.3048 n-C 3
H
7 3-OCH 3
-C
6
H
4 A.3049 n-C 3
H
7 4-OCH 3
-C
6
H
4 A.3050 n-C 3
H
7 3-acetyl-C 6
H
4 A.351n-C 3
H
7 4-acetyl-C 6
H
4 6 R1 0050/46043 191 No.R24 A.3052 n-C 3
H
7 3 -methoxycarbonyl-C 6
H
4 A. 3053 n-C 3
H
7 4-methoxycarbonyl-C 6
H
4 A.3054 fl-C 3
H
7 3-CF 3
-C
6
H
4 A.3055 n-C 3
H
7 4-CF 3
-C
6
H
4 A.3056 n-C 3
H
7 2-naphthyl A. 3057 n-C 3
H
7 6-chloropyridazin3..yl A. 3058 n-C 3
H
7 5-chloropyrazin-2-y1 A.3059 n-C 3
H
7 quinolin-2-yl A.3060 n-C 3
H
7 2, 5-dimethylpyrazin-3.yl A.3061 n-C 3
H
7 pyrazin-2-yl A.3062 n-C 3
H
7 3-chloropyrid-2-yl A.3063 n-C 3
H
7 6-chloropyrid-2-yl A. 3064 n-C 3
H
7 4-trifluoromethyl, 6-chloropyrid-2-yl A. 3065 n-'37-trifluoromethylpyrid2..y± A.3066 n-C 3
H
7 6-trifluoromethylpyrid-2 -yl A.3067 n-C 3
H
7 6-methoxypyrid-2-yl A.3068 n-C 3
H
7 5-chloropyrid-2-yl A.3069 n-C 3
H
7 pyrid-2-yl A.3070 n-C 3
H
7 benzothiazol-2-yl A. 3071 n-C 3
H
7 7-chloroquinolin-4-yl A.3072 n-C 3
H
7 3-nitropyrid-2-yl A.3073 n-C 3
H
7 pyrrol-3-yl A.3074 n-C 3
H
7 pyrrol-2-yl A. 3075 n-C 3
H
7 2, 6-dioctylpyrid-4.yl A.3076 n-C 3
H
7 5-nitropyrid-2-yl A.3077 n-C 3
H
7 pyrid-4-y.
A.3078 n-C 3
H
7 pyrid-3-y.
A.3079 n-C 3
H
7 pyrimidin-2-yl A.3080 n-C 3
H
7 pyrimidin-4-yl A.3081 n-C 3
H
7 quinazolin-4-yl A. 3082 n-C 3
H
7 6-chloropyrimidin4.y.
A.3083 n-C 3
H
7 6-methoxypyrimidin-4 -yl A. 3084 n-C 3 7 2,5, 6-trichloropyrimidin4yl A. 3085 n-C 3
H
7 2, 6-dimethylpyrimidin-4-yl A.3086 n-C 3
H
7 2-methyl, 6-chloropyrimidin-4-yl A.3087 n-C 3
H
7 2-methyl, 6-ethoxypyrinidin-4-yl A. 3088 n-C 3
H
7 4,5, 6-trichloropyrimidin2.yl A. 3089 n-C 3
H
7 4, 6-dimethoxypyrimidin-2.yl A. 3090 n-C 3
H
7 14, 6-dimethylpyrimidin-2-yl A' 7c 2 0050/46043 192 N~o.R2R4 A. 3091 n-C 3
H
7 4, 6-dichloropyrimidin-2-yl A. 3092 n-C 3
H
7 4-methyl, 6-methoxypyrimidin-2-yl A.3093 n-C 3
H
7 4-chioro, 6-methoxypyrimidin-2-y1 A. 3094 n-C 3
H
7 6-chloroquinoxalin-2-yl A.3095 n-C 3
H
7 3,6-dichloro-1,2,4-triazin.5.yl A.3096 n-C 3
H
7 4-methoxy-1, 3, 5-triazin-2-yl A.3097 n-C 3
H
7 4-ethoxy-1,3,5-triazin-2-yl A.3098 n-C 3
H
7 4,6-dichloro-1,3,5-triazin-2.yl A.3099 n-C 3
H
7 4-ethoxy, 6-chloro-1, 3, 5-triazin-2-yl A.3100 n-C 3
H
7 isoxazol-3-yl A.3101 n-C 3
H
7 thien-2-yl A.3102 In-C 3
H
7 fur-2-yl A.3103 n-C 3
H
7 A.3104 n-C 3
H
7 -chloropropen-3-yi A.3105 n-C 3
H
7 4 -chlorophenyl)but-2-en-1-yl A.3106 n-C 3
H
7 propyn-3-yl A.3107 n-C 3
H
7 methylcarbonyl A.3 108 n-C 3
H
7 ethylcarbonyl A.3109 n-C 3
H
7 n-propylcarbonyl A.3110 n-C 3
H
7 i-propylcarbonyl A.3111 n-C 3
H
7 n-butylcarbonyl A.3112 n-C 3
H
7 s-butylcarbonyl A.3 113 n-C 3
H
7 i-butylcarbonyl A.3 114 n-C 3
H
7 t-butylcarbonyl A.3 115 n-C 3
H
7 n-pentylcarbonyl A.3116 n-C 3
H
7 i-pentylcarbonyl A.3 117 n-C 3
H
7 neo-pentylcarbonyl A.3 118 n-C 3
H
7 n-hexylcarbonyl A.3119 n-C 3
H
7 n-octylcarbonyl A.3120 n-C 3
H
7 1-propenylcarbonyl A. 3121 n-C 3
H
7 2-penten-1-yl-carbonyl A.3122 n-C 3
H
7 2, 5-heptadien-1-yl-carbonyl A.3123 n-C 3
H
7 benzoyl A.3124 n-C 3
H
7 2-chlorobenzoyl A.3125 n-C 3
H
7 3-chlorobenzoyl A.3126 n-C 3
H
7 4-chlorobenzoyl A.3127 n-C 3
H
7 2-cyanobenzoyl A.3128 n-C 3
H
7 3-cyanobenzoyl A. 312 9 n-C 3
H
7 4-cyanobenzoyl i0, 0050/ 46043 193 No.R24 A.3130 n-C 3
H
7 4-methoxybenzoyl A.3131 n-C 3
H
7 2-pyridylcarbonyl A.3132 n-C 3
H
7 3-pyridylcarbonyl A.3133 n-C 3
H
7 4-pyridylcarbonyl A. 3134 n-C 3
H
7 2-pyrimidinylcarbonyl A.3135 n-C 3
H
7 2-oxazolylcarbonyl A. 3136 n-C 3
H
7 A.3137 In-C 3
H
7 methylsulfonyl A.3138 n-C 3
H
7 ethylsulfonyl A.3139 n-C 3
H
7 n-propylsulfonyl A.3140 n-C 3
H
7 i-propylsulfonyl A.3141 n-C 3
H
7 n-butylsulfonyl A.3142 n-C 3
H
7 t-butylsulfonyl 7C H7A n-pentyisuifonyi A.3144 n-C 3
H
7 neo-pentylsu.fonyl A.3145 n-C 3
H
7 n-hexylsulfonyl A.3146 n-C 3
H
7 n-octylsulfonyl A.3147 n-C 3
H
7 phenylsulfonyl A. 3148 n-C 3
H
7 2-chlorophenylsulfonyl A. 3149 n-C 3
H
7 3-chlorophenylsulfonyl A. 3150 n-C 3
H
7 4-chlorophenylsulfonyl A. 3151 n-C 3
H
7 2-cyanophenylsulfonyl A. 3152 n-C 3
H
7 3-cyanophenylsulfonyl A. 3153 n-C 3
H
7 4-cyanophenylsulfonyl A.3154 n-C 3
H
7 2-pyridylsulfonyl A.3155 n-C 3
H
7 3-pyridylsulfonyl A.3156 In-C 3
H
7 4-pyridylsulfonyl A. 3157 n-C 3
H
7 2-pyrimidinylsulfonyl A.3158 n-C 3
H
7 4-oxazolylsulfonyl A. 3159 n-C 3
H
7 5-chlorothiazol-2-ylsulfonyl A.3160 n-C 3
H
7 2-t-C 4
H
9
-C
6
H
4
-CH
2 A. 3161 n-C 3
H
7 3-t-C 4
H
9
-C
6
H
4
-CH
2 A.3162 n-C 3
H
7 4-t-C 4 H9-C 6
H
4
-CH
2 A.3163 n-C 3
H
7 2-(4'-chlorothiazol-2'-yloxy)eth-1-yl A.3164 n-C 3
H
7 1 -methylpyrazol-4 '-yloxy)eth-1-yl A.3165 n-C 3
H
7 4-Br-C 6
H
4 A.3166 n-C 3
H
7 3,5-(CH 3 2
-C
6
H
3 A.3167 n-C 3
H
7 4-C 2
H
5
-C
6
H
4 A. 3168 n-C 3
H
7 3-dimethylaminocarbonyl-C 6
H
4 0050/46043 194 No.R24 A. 3169 n-C 3
H
7 4-dimethylaminocarbonyl-C 6
H
4 A.3170 n-C 3
H
7 2-hydroxyprop-1-yl A. 3171 n-C 3
H
7 6 -hydroxy-2-methylpyrimidin.4.ylmethyl A.3172 n-C 3
H
7 6 -OH,2-CH(CH 3 2 -pyrimidin4.y].CH 2 A.3173 n-C 3
H
7 6 -OH,2-CH(CH 2 2 -pyrimidin4yl]..CH 2 A.3174 n-C 3
H
7 5-(2'-furan)pent-1-yl A.3175 n-C 3
H
7 5-(2 '-N-methylpyrrol)pent-1.yl A.3176 n-C 3
H
7 2 -(4-Cl-C6H4)oxazol-4-yl]-CH 2 A.3177 n-C 3
H
7 3-CF 3 -pyridin-2-yl A.3178 n-C 3
H
7 5-CF 3 -pyridin-2-yl A.3179 n-C 3
H
7 6-(2'-thienyl)hex-1-yl A.3180 n-C 3
H
7 (E)-3-chlorobut-2-en-1-yl A. 3181 n-C 3
H
7 (Z )-3-chlorobut-2-en-1-yl 10'1~n E)--brmbt2-n1y A.3 1830 n-C- 3
H
7 (Z)-2-bromobut-2-en-1-yl A.3183 n-C 3
H
7 (E)-1-croro--en--yl A.3 185 n-C 3
H
7 (Z )-1-chloroprop-1-en-3-yl A.3186 n-C 3
H
7 but-1-en-3-yl A.3187 n-C 3
H
7
CH
2
CH
2 Br A.3188 n-C 3
H
7
CH
2
CH
2
CH
2 Br A.3189 n-C 3
H
7
CH
2
CH
2
CH
2
CH
2 Br A.3 190 n-C 3
H
7 2-methoxyprop-1-yl A.3191 n-C 3
H
7 2-ethoxyprop-1-yl A. 3192 n-C 3
H
7 2-isopropoxyprop-1-yl A.3193 n-C 3
H
7 but-1-yn-3-yl A.3194 n-C 3
H
7 but-1-yn-4-yl A.3195 n-C 3
H
7 but-2-yn-4-yl A.3196 fl-C 3
H
7 pent-1-yn-4-yl A.3197 fl-C 3
H
7 pent-2-yn-4-yl A.3198 n-C 3
H
7 A.3199 n-C 3 7 A. 3200 n-C 3
H
7 E-2-chlorobut-2-en-1-yl A. 3201 n-C 3
H
7 Z-2-chlorobut-2-en-1-yl A.3202 n-C 3
H
7 Z-1-chloroprop-1-en-3-yl A. 3203 n-C 3
H
7 2-methylprop-1-en-3-yl A. 3204 n-C 3
H
7 2-chloroprop--e--3-yl A. 3205 n-C 3
H
7 2-bromoprop-1-en-3-yl A.3206 n-C 3
H
7 but-2-en-1-yl A.3207 n-C 3
H
7 but-3-en-1-yl 0050/ 46043 195 No. R 2
R
A. 3208 n-C 3
H
7 1-iodoprop-1-yn-3-yl A. 3209 n-C 3
H
7 E-3-bromobut-2-en-1-yl A. 3210 n-C 3
H
7 Z-3-bromobut-2-en-1-yl A.3211 fl-C 4
H
9
H
A.3212 n-C 4
H
9 CH 3 A.3213 n-C 4
H
9
C
2
H
A.3214 n-C 4
H
9 n-C 3
H
7 A.3215 in-C 4
H
9 i-C 3
H
7 A.3216 n-C 4
H
9 cyclopropyl A.3217 n-C 4
H
9 n-C 4
H
9 A.3218 n-C 4 H9 S-C 4
H
9 A.3219 n-C 4
H
9 i-C 4 H9 A.3220 n-C 4 H9 t-C 4
H
9 i -LL C H 9
CH
2
CH
2 C1 A.3222 n-C 4
H
9
CH
2
CH
2
CH
2 Cl A.3223 n-C 4 H9 CH 2
CH
2 Br A.3224 n-C 4 H9 CH 2
CH
2
CH
2 Br A.3225 n-C 4 H9 CH 2
CH
2
CN
A.3226 n-C 4 Hq CH 2
CH
2
CH
2
CN
A.3227 n-C 4 Hq cyclopropylmethyl A. 3228 n-C 4 Hq 2-cyclopropyleth-1-yJ.
A.3229 n-C 4 Hq 2-methoxyeth-1-yl A.3230 n-C 4 Hq 2-ethoxyeth-1-yl A. 3231 n-C 4 Hq 2-isopropoxyeth-1-yl A.3232 n-C 4 Hq 3-methoxyprop-1-yl A.3233 n-C 4
H
9 3-ethoxyprop-1-yl A. 3234 n-C 4 Hq 3-isopropoxyprop-1-yl A.3235 n-C 4 Hq 4-methoxybut-1-yl A.3236 In-C 4 Hq 4-isopropoxybut-1-yl A.3237 n-C 4 Hq propen-3-yl A.3238 n-C 4 Hq but-2-en-1-yl A.3239 n-C 4 Hq 2-methoxyprop-1-yl A.3240 n-C 4 Hq 2-ethoxyprop-1-yl A. 3241 n-C 4 Hq 2-isopropoxyprop-1-yl A.3242 n-C 4 Hq but-1-yn-3-yl A.3243 n-C 4 Hq but-1-yn-4-yl A.3244 n-C 4 Hq but-2-yn-4-yl A.3245 n-C 4 Hq pent-1-yn-4-yl A.3246 in-C 4
H
9 lpent-2-yn-4-yl 0050/46043 196 No.R24 A. 3247 n-C 4
H
9 A.3248 n-C 4
H
9 A. 3249 n-C 4
H
9 E-2-chlorobut-2-en-1-yl A. 3250 n-C 4
H
9 Z-2-chlorobut-2-en-1-yl A. 3251 n-C 4
H
9 E-1-chloroprop-l-en-3-yl A. 3252 n-C 4
H
9 2-methylprop-l-en-3-yl A. 3253 n-C 4 Hq 2 -chloroprop-1-en-3-y.
A. 3254 n-C 4
H
9 2-bromoprop-1--en-3-yl A.3255 n-C 4
H
9 but-2-en-1-yl A.3256 n-C 4
H
9 but-3-en-1-yl A. 3257 n-C 4 Hq l-iodoprop-1-yn-3-yl A.3258 n-C 4 H9 propargyl A.3259 i-C 4 Hq
H
A.3260 i-C 4
H
9 CH 3 A.3261 i-C 4 Hq
C
2
H
A.3262 i-C 4
H
9 n-C 3
H
7 A.3263 i-C 4
H
9 i-C 3
H
7 A.3264 i-C 4 Hq cyclopropyl A.3265 i-C 4 Hq n-C 4
H
9 A.3266 i-C 4 Hq
S-C
4
H
9 A.3267 i-C 4 Hq i-C 4
H
9 A.3268 i-C 4 Hq t-C 4 H9 A.3269 i-C 4 Hq
CH
2
CH
2 Cl A.3270 i-C 4 Hq
CH
2
CH
2
CH
2 Cl A.3271 i-C 4
H
9 CH 2
CH
2 Br A.3272 i-C 4
H
9 CH 2
CH
2
CH
2 Br A.3273 i-C 4
H
9 CH 2
CH
2
CN
A.3274 i-C 4
H
9 CH 2
CH
2
CH-
2
CN
A.3275 i-C 4
H
9 cyclopropylmethyl A. 3276 i-C 4
H
9 2-cyclopropyleth-1-yl A.3277 i-C 4
H
9 2-methoxyeth-1-yl A.3278 i-C 4 H9 2-ethoxyeth-1-yl A. 3279 i-C 4
H
9 2-isopropoxyeth-1.yl A.3280 i-C 4
H
9 3-methoxyprop-1-yl A.3281 i-C 4
H
9 3-ethoxyprop-1-yl A. 3282 i-C 4
H
9 3-isopropoxyprop-1-yl A.3283 i--C 4
H
9 4-methoxybut-1-yl A. 3284 i-C 4 Hq 4-isopropoxybut-1-yl A.3285 i--C 4 H9 propen-3-yl 71 0050/46043 197 No.R24 A3286 i-C 4
H
9 but-2-en-1-y.
A.3287 i-C 4
H
9 2-methoxyprop-1-yl A.3288 i-C 4 H9 2-ethoxyprop-1-yl A. 3289 i-C 4
H
9 2-isopropoxyprop-1-yl A.3290 i-C 4 H9 but-1-yn-3-yl A.3291 i-C 4
H
9 but-1-yn-4-yl A.3292 i-C 4
H
9 but-2-yn-4-yl A.3293 i-C 4
H
9 pent-1-yn-4-yl A.3294 i-C 4 H9 pent-2-yn-4-yl A.3295 i-C 4
H
9 A.3296 i-C 4
H
9 A. 3297 i-C 4
H
9 E-2-chlorobut-2-en-1-yl A. 3298 i-C 4
H
9 Z-2-chlorobut-2-en-1-yl A. 3299 i-C 4
H
9 E-i-chioroprop-1-en-3-yl A. 3300 ji-C 4 Hq 2-methylprop-1-en-3-y.
A. 3301 i-C 4
H
9 2-chloroprop-1-en-3-y.
A. 3302 i-C 4
H
9 2-bromoprop-l-en-3-yl A.3303 i-C 4
H
9 but-2-en-1-yl A.3304 i-C 4
H
9 but-3-en-1-yl A.3305 i-C 4
H
9 1-iodoprop-1-yn-3-yl A.3306 i-C 4
H
9 propargy.
A.3307 n-C 5 gH 11 H A.3308 n-C 5
H
11 CH 3 A.3309 n-C 5 Hll
C
2
H
A.3 310 n-C 5
H
11 n-C 3
H
7 A.3311 n-C 5
H
11 i-C 3
H
7 A.3312 n-C 5
H
1 1 cyclopropyl A.3313 n-C 5 Hl 1 n-C 4
H
9 A.3314 n-C 5 Hll
S-C
4
H
9 A.3315 n-C 5 Hll i-C 4
H
9 A.3316 fl-C 5
H
1 1 t-C 4
H
9 A.3317 n-C 5
H
1 1 CH 2
CH
2 Cl A.3318 n-C 5
H
1 1 CH 2
CH
2
CH
2 Cl A.3319 n-C 5 Hll
CH
2
CH
2 Br A.3320 n-C 5
H
1 1 CH 2
CH
2
CH
2 Br A.3321 n-C 5 Hll
CH
2
CH
2
CN
A.3322 n-C 5 Hll
CH
2
CH
2
CH
2
CN
A.3323 n-C 5 Hll cyclopropylmethyl A. 3324 n-C 5 Hll 2-cyclopropyleth-1.-yl 0050/46043 198 No.R24 A. 3325 n-C 5 Hll 2-methoxyeth-1-yl A.3326 n-C 5 Hll 2-ethoxyeth-1-yl A.3327 n-c 5
H
11 2-isopropoxyeth-1-yl A.3328 n-C 5 Hll 3-methoxyprop-1-yl A.3329 n-C 5
H
11 3-ethoxyprop-1-yl A.3330 n-C 5 Hll 3-isopropoxyprop-1-yl A.3331 n-C 5
HI
1 4-methoxybut-l-yl A. 3332 n-C 5 HII 4-isopropoxybut- 1-yl A.3333 n-C 5 Hll propen-3-yl A.3334 n-C 5 Hll but-2-en-1-yl A.3335 n-C 5 Hl 1 2-methoxyprop-1-y.
A.3336 n-C 5
HI
1 2-ethoxyprop-1-yl A. 3337 n-C 5 Hll 2-isopropoxyprop-1-y.
A. 3339 n-C 5
H
11 but-1-yn-4-yl A.3339 n-C 5 Hll but-2-yn-4-yl A.3340 n-C 5 Hll pet--yn-4-yl A.3342 n-C 5
H
11 pent-2-yn-4-yl A.3342 n-C 5 Hll pent-1-yn-4-yl A.3344 n-C 5 Hll A. 3345 n-C 5 Hll pe-2-orb--en-- A. 3346 n-C 5 Hll Z-2-chlorobut-2-en-1-yl A. 3347 n-C 5 Hll E-1-chloroprop-l-en-3-yl A. 3348 n-C 5 Hll 2-methylprop-l-en-3-yl A. 3349 n-CSHII 2-chloroprop-1-en-3-yl A. 3350 n-C 5 Hll 2-bromoprop-l-en-3-yl A.3351 n-C 5 Hll but-2-en-1-yl A.3352 n-CSHII but-3-en-1-yl A.3353 n-C 5 Hll 1-iodoprop-1-yn-3-yl A.3354 n-C 5
H
11 propargyl A.3355 CYClo-C 5 Hq H A.3356 CYClo-C 5
H
9
CH
3 A.3357 cyclo-C 5
H
9
C
2
H
A.3358 CYClo-C 5 Hq n-C 3
H
7 A.3359 CYC1o-C 5
H
9 i-C 3
H
7 A.3360 CYClo-C 5
H
9 cyclopropyl A.3361 CYClo-C 5
H
9 n-C 4
H
9 A.3362 CYClo-C 5
H
9
S-C
4 H9 A.3363 ICYC1o-C 5
H
9 i-C 4 H9 Ar{ 0050/46043 199 No. R 2
R
A.3364 CYClO-C 5 Hq t-C 4
H
9 A.3365 CYClo-C 5
H
9
CH
2
CH
2 C1 A.3366 CYC1o-C 5 H9 CH 2
CH
2
CH
2 Cl A.3367 CYClo-C 5 Hg CH 2
CH
2 Br A.3368 CYClo-C 5
H
9
CH
2
CH
2
CH
2 Br A.3369 ICYClo-C5H 9
CH
2
CH
2
CN
A.3370 CYClo-C 5
H
9
CH
2
CH
2
CH
2
CN
A. 3371 cyclo-C 5
H
9 cyclopropylmethyl A. 3372 CYC1o-C 5
H
9 2-cyclopropyleth-1-yl A. 3373 CYC1o-C 5
H
9 2-methoxyeth-1-yl A. 3374 cyclo-CsH 9 2-ethoxyeth-1-yl A. 3375 cyclo-C 5
H
9 2-isopropoxyeth-1-yl A. 3376 cyclo-C 5 gHg 3-methoxyprop-1-yl A. 3377 CYCiO-C 5
H
9 3-ethoxyprop-i-yi A. 3378 CYClo-C 5
H
9 3-isopropoxyprop-1-yl A. 3379 CYClo-C 5
H
9 4-methoxybut-1-yl A.3380 CYClo-C 5
H
9 4-isopropoxybut-1-yl A.3381 cyclo-C 5
H
9 propen-3-yl A.3382 CYClo-C 5 Hq but-2-en-1-yl A. 3383 CYC1o-C 5
H
9 2-methoxyprop-1-yl A. 3384 CYC1o-C 5 H9 2-ethoxyprop-1-yl A. 3385 CYC1o-C 5
H
9 2-isopropoxyprop-1-yl A.3386 CYC1o-C 5
H
9 but-1-yn-3-yl A.3387 CYC1o-C 5 H9 but-1-yn-4-yl A.3388 cyclo-C 5 H9 but-2-yn-4-yl A.3389 CYClo-C 5 H9 pent-1-yn-4-yl A.3390 CYClo-C 5 H9 pent-2-yn-4-yl A.3391 ICYClo-C 5 H9 A.3392 CYClo-C 5 H9 A. 3393 CYClo-C 5 Hq E-2-chlorobut-2-en-1-yl A. 3394 CYClo-C 5 Hq Z-2-chlorobut-2-en-1-yl A. 3395 cyclo-C 5
H
9 E-1-chloroprop-1--en-3-yl A. 3396 cyclo-C 5 H9 2-methylprop-1-en-3-yl A. 3397 cyclo-C 5
H
9 2-chloroprop-1-en-3-yl A. 3398 CYClo-C 5
H
9 2-bromoprop-1-en-3-yl A.3399 CYClo-C 5 Hq but-2-en-1-yl A.3400 CYClo-C 5 H9 but-3-en--1-yl A. 3401 CYCJ1o-C 5 H9 1-iodoprop-1-yn-3-yl A.3402 CYClo-C 5
H
9 propargyl 0050/46043 200 No.R24 A. 3403 n-C 6 Hl 3
H
A.3404 n-C 6
H
1 3 CH 3 A. 3405 n-C 6 Hl 3 C 2
H
A. 3406 n-C 6 Hl 3 n-C 3
H
7 A.3407 n-C 6 Hl 3 i-C 3
H
7 A. 3408 n-C 6 Hl 3 cyclopropyl A.3409 n-C 6 Hl 3 n-C 4 H9 A.3410 n-C 6 Hl 3
S-C
4
H
9 A.3411 n-C 6 Hl 3 i-C 4 H9 A.3412 n-C 6 Hl 3 t-C 4
H
9 A.3413 n-C 6 Hl 3 CH 2
CH
2 C1 A.3414 n-C 6 Hl 3 CH 2
CH
2
CH
2 Cl A.3415 n-C 6 Hl 3
CH
2
CH
2 Br A.3416 -C 6 11 13
CH
2
CH
2
CH
2 Br A.3417 n-C 6 Hl 3
CH
2
CH
2
CN
A.3418 n-C 6 Hl 3
CH
2
CH
2
CH
2
CN
A.3419 n-C 6 Hl 3 cyclopropylmethyl A.3420 n-C 6 Hl 3 2-cyclopropyleth-1-yl A.3421 n-C 6 Hl 3 2-methoxyeth-1-yl A.3422 n-C 6 Hl 3 2-ethoxyeth-1-yl A. 3423 n-C 6 Hl 3 2-isopropoxyeth-1-yl A.3424 n-C 6 Hl 3 3-methoxyprop-1-yl A.3425 n-C 6 Hl 3 3-ethoxyprop-1-yl A. 3426 n-C 6 Hl 3 3-isopropoxyprop-1-yl A.3427 n-C 6 Hl 3 4-methoxybut-l-yl A. 3428 n-C 6 Hl 3 4-isopropoxybut-1-yl A.3429 n-C 6 Hl 3 propen-3-yl A.3430 n-C 6 Hl 3 but-2-en-1-yl A.3431 n-C 6 Hl 3 2-methoxyprop-1-yl A.3432 n-C 6 Hl 3 2-ethoxyprop-1-yl A. 3433 n-C 6 Hl 3 2-isopropoxyprop-1-yl A.3434 n-C 6
H
13 but-1-yn-3-yl A.3435 n-C 6 Hl 3 but-1-yn-4-yl A.3436 n-C 6 Hl 3 but-2-yn-4-yl A.3437 n-C 6 Hl 3 pent-1-yn-4-yl A.3438 n-C 6 Hl 3 pent-2-yn-4-yl A.3439 n-C 6 Hl 3 A.3440 n-C 6
HI
3 A. 3441 In-C 6
HI
3 E-2-chlorobut-2-en-1-yl 0050/46043 201 No.R24 A.3442 n-C 6 Hl 3 Z-2-chlorobut-2-en-1-yl A. 3443 n-C 6 Hl 3 E-1-chloroprop-l-en-3-yl A. 3444 n-C 6 Hl 3 2-methylprop-l-en-3-yl A. 3445 n-C 6 Hl 3 2-chloroprop-l-en-3-yl A.3446 n-C 6 Hl 3 2-bromoprop--en-3-yl A.3447 n-C 6 Hl 3 but-2-en-1-yl A.3448 n-C 6 Hl 3 but-3-en-1-yl A. 3449 n-C 6 Hl 3 1-iodoprop-1-yn-3-yl A.3450 n-C 6
HI
3 propargyl A.3451 CYC1o-C 6
H
11
H
A.3452 CYC1o-C 6
H
11
CH
3 A.3453 CYClo-C 6
H
11
C
2
H
A.3454 CYC1o-C 6
H
11 n-C 3
H
7 A.3455 CYCio-C 6
H
11
I-C;
3
H
7 A.3456 CYClo-C 6
H
11 cyclopropyl A.3457 CYClo-C 6
H
11 n-C 4
H
9 A.3458 CYC1o-C 6
H
11
S-C
4
H
9 A.3459 CYClo-C 6
H
11 i-C 4
H
9 A.3460 CYC1o-C 6
H
11 t-C 4
H
9 A.3461 CYClo-C 6
H
11
CH
2
CH
2 Cl A.3462 CYClo-C 6
H
1 1
CH
2
CH
2
CH
2 Cl A.3463 CYC1o-C 6
H
1 1
CH
2
CH
2 Br A.3464 CYC1o-C 6
H
1 1
CH
2
CH
2
CH
2 Br A.3465 CYC1o-C 6
H
1 1
CH
2
CH
2
CN
A.3466 CYClo-C 6
H
1 1
CH
2
CH
2
CH
2
CN
A. 3467 CYC1o-C 6
H
1 1 cyclopropylmethyl A.3468 CYClo-C 6
H
1 1 2-cyclopropyleth-1-yl A.3469 CYClo-C 6
H
1 1 2-methoxyeth-1-yl A. 3470 CYC1o-C 6
H
1 1 2-ethoxyeth-1-yl A. 3471 CYC1o-C 6
H
1 1 2-isopropoxyeth-1-yl A.3472 CYClo-C 6
H
1 1 3-methoxyprop-1-yl A. 3473 CYClo-C 6
H
1 1 3-ethoxyprop-1-yl A.3474 CYClo-C 6
H
11 3-isopropoxyprop-1-yl A.3475 CYC1o-C 6
H
11 4-methoxybut-1-yl A.3476 CYClo-C 6
H
11 4-isopropoxybut-1-y.
A.3477 CYC1o-C 6
H
11 properi-3-yl A.3478 CYClo-C 6
H
11 but-2-en-1-yl A. 3479 CYClo-C 6
H
11 2-methoxyprop-1-yl A.3480 CYC1o-C 6
H
11 2-ethoxyprop-1-yl 0050/46043 202 No.R24 A. 3481 CYClo-C 6 Hjj 2-isopropoxyprop-1-yl A.3482 CYClo-C 6 Hjj but-1-yn-3-yl A.3483 CYClo-C 6
H
11 but-1-yn-4-yl A.3484 cyclo-C 6 Hll but-2-yn-4-yl A.3485 CYClo-C 6
H
11 pent-1-yn-4-yl A.3486 CYClo-C 6
H
1 1 pent-2-yn-4-yl A.3487 CYClo-C 6
H
11 A.3488 CYClo-C 6
H
11 A. 3489 CYC1o-C 6
H
11 E-2-chlorobut-2-en-1-yl A. 3490 CYClo-C 6
H
11 Z-2-chlorobut-2-en-1-yl A. 3491 CYClo-C 6
H
11 E-1-chloroprop-1-en-3-yl A. 3492 CYClo-C 6
H
11 2-methylprop-1-en-3-yl A. 3493 CYClo-C 6
H
11 2-chloroprop-l-en-3-y.
Z% t A-2CCl A6~ 2-bromoprop-i-en-3-yl A.3495 CYClo-C 6
H
11 but-2-en-1-yl A.3496 CYC1o-C 6
H
11 but-3-en-1-yl A. 3497 CYC1o-C 6
H
11 1-iodoprop-1-yn-3-yl A.3498 CYClo-C 6
H
11 propargyl A.3499 H H A.3500 H CH 3 A.3501 H
C
2
H
A.3502 H n-C 3
H
7 A.3503 H i-C 3
H
7 A.3504 H cyclopropyl A.3505 H n-C 4 Hq A.3506 H S-C 4
H
9 A.3507 H i-C 4 H9 A.3508 H t-C 4
H
9 A.3509 H
CH
2
CH
2 C1 A.3510 H
CH
2
CH
2
CH
2 C1 A.3511 H
CH
2
CH
2 Br A.3512 H CH 2
CH
2
CH
2 Br A.3513 H CH 2
CH
2
CN
A.3514 H CH 2
CH
2
CH
2
CN
A.3515 H cyclopropylmethyl A.3516 H 2-cyclopropyleth-1-yl A.3517 H 2-methoxyeth-1-yl A.3518 H 2-ethoxyeth-1-yl h A31 H 2-isopropoxyeth-1-yl i_ f-13 0050/46043 203 No.R24 A.3520 H 3-methoxyprop-1-yl A.3521 H 3-ethoxyprop-1-yl A.3522 H 3-isopropoxyprop-1-yl A.3523 H 4-methoxybut-1-yl A.3524 H 4-isopropoxybut-1-yl A.3525 H propen-3-yl A.3526 H but-2-en-1-yl A.3527 H 2-methoxyprop-1-yl A.3528 IH 2-ethoxyprop-1-yl A.3529 H 2-isopropoxyprop-1-yl A.3530 H but-1-yn-3-yl A.3531 H but-1-yn-4-yl A.3532 IH but-2-yn-4-yl A.-3 5-3-3 1 H pent-1-yn-4-y A.3534 H pent-2-yn-4-yl A.3535 H A.3536 H A.3537 H E-2-chlorobut-2-en-1-yl A.3538 H Z-2-chlorobut-2-en-.-yl A.3539 H E-1-chloroprop-l-en-3-yl A.3540 H 2-methylprop-1-en-3-yl A.3541 H 2-chloroprop-1-en-3-yl A.3542 H 2-bromoprop-l-en-3-yl A.3543 H but-2-en-1-yl A.3544 H but-3-en-1-yl A.3545 H 1-iodoprop-1-yn-3-yl A.3546 H propargyl A.3547 CYClo-C 4
H
7
H
A.3548 CYClo-C 4
H
7
CH
3 A.3549 CYC1o-C 4
H
7
C
2
H
A.3550 CYClo-C 4
H
7 n-C 3
H
7 A.3551 CYClo-C 4
H
7 i-C 3
H
7 A.3552 cyclo-C 4
H
7 cyclopropyl A.3553 CYClo-C 4
H
7 n-C 4 H9 A.3554 CYClo-C 4
H
7
S-C
4 H9 A.3555 CYClo-C 4
H
7 i-C 4
H
9 A.3556 CYClo-C 4
H
7 t-C 4 H9 A.3557 CYClo-C 4
H
7
CH
2
CH
2 Cl A.3558 CYClo-C 4
H
7
CH
2
CH
2
CH
2 Cl 0050/46043 204 No.R24 A. 3559 CYClo-C 4
H
7
CH
2
CH
2 Br A.3560 CYClo-C 4
H
7
CH
2
CH
2
CH
2 Br A.3561 CYClo-C 4
H
7
CH
2
CH
2
CN
A.3562 CYClo-C 4
H
7
CH
2
CH
2
CH
2
CN
A. 3563 CYClo-C 4
H
7 cyclopropylmethyl A.3564 CYC1o-C 4
H
7 2 -cycloopropyleth-1-yl A. 3565 CYClo-C 4
H
7 2-methoxyeth-1-yl A. 3566 CYClo-C 4
H
7 2-ethoxyeth-1-yl A. 3567 CYC1o-C 4
H
7 2-isopropoxyeth-1-yl A. 3568 CYC1o-C 4 1 7 3-methoxyprop-1-yi A. 3569 CYC1o-C 4
H
7 3-ethoxyprop-1-yl A. 3570 CYClo-C 4
H
7 3 -isopropoxyprop-1-yl A. 3571 CYClo-C 4
H
7 4-methoxybut-1-yl A 3572 Icyclo-C 4
H
7 4-isopropoxybut-'1-yl A.3573 CYC1o-C 4
H
7 propen-3-yl A.3574 CYClo-C 4
H
7 but-2-en-1-yl A. 3575 CYC1o-C 4
H
7 2-methoxyprop-1-yl A. 3576 CYClo.-C 4
H
7 2-ethoxyprop-1-yl A. 3577 CYClo-C 4
H
7 2 -isopropoxyprop-1-yl A.3578 CYC1o-C 4
H
7 but-1-yn-3-yl A.3579 CYC1o-C 4
H
7 but-1-yn-4-yl A.3580 cyclo-C 4
H
7 but-2-yn-4-yl A.3581 CYClo-C 4
H
7 pent-1-yn-4-yl A.3582 CYC1o-C 4
H
7 pent-2-yn-4-yl A.3583 CYC10-C 4
H
7 A.3584 CYC1o-C 4
H
7 A. 3585 CYClo-C 4
H
7 E-2-chlorobut-2-en-1-yl A. 3586 CYClo-C 4
H
7 Z-2-chlorobut-2-en-1-yl A. 3587 CYC1o-C 4
H
7 E-1-chloroprop-l-en-3-yl A. 3588 CYC 1o-C 4
H
7 2-methylprop-l-en-3-yl A. 3589 cYC1o-C 4
H
7 2-chloroprop-l-en-3-yl A. 3590 CYClo-C 4
H
7 2-bromoprop-l-en-3-yl A.3591 CYClo-C 4
H
7 but-2-en-1-yl A.3592 CYClo-C 4
H
7 but-3-en-1-yl A.3593 CYClo-C 4
H
7 1-iodoprop-1-yn-3-yl [A.3594 ICYClO-C 4
H
7 propargyl 0050/46043 205 Table B No. R 3 B. 1 CH 2
CN
B.2 (CH 2 2
CN
B. 3 (CH 2 3
CN
BA4 (CH 2 4
CN
B. 5
CH
2
NO
2 B.6
(CH
2 2 N0 2 B.7
(CH
2 3 N0 2 B. 8
(CH
2 4 N0 2 B.9 CH 2 0H B. 10 (CH 2 2 0H B.11 (CH 2 3 0H B. 12 (CH 2 4 0H B.13
CH
2
NH
2 B.14
(CH
2 2
NH
2
(CH
2 3
NH
2 B.16
(CH
2 4
NH
2 B.17
CH
2
NHCH
3 B.18
(CH
2 2
NHCH
3 B.19
(CH
2 3
NHCH
3
(CH
2 4
NHCH
3 B.21
CH
2
N(CH
3 2 B.22
(CH
2 2
N(CH
3 2 B.23
(CH
2 3
N(CH
3 2 B.24
(CH
2 4
N(CH
3 2
CH
2
N(CH
2
CH
3 2 B.26
(CH
2 2
N(CH
2
CH
3 2 B.27
(CH
2 3
N(CH
2
CH
3 2 B.28
(CH
2 4
N(CH
2
CH
3 2 B.29
CH
2
OCH
3
(CH
2 2 0CH 3 B.31
(CH
2 3 0CH 3 B.32
(CH
2 4 0CH 3 B.33 CH 2 OCHgCH-a B.34
(CH
2 2
OCH
2
CH
3
(CH
2 3 0CH 2
CH
3 B.36 (CH 2 4
OCH
2
CH-A
B.37
CH
2 0O(CH 2 2
CH
3 /V7- 0050/46043 206 No. R 3 B.38
(CH
2 2 0(CH 2 2
CH
3 B.39
(CH
2 3 0(CH 2 2
CH
3
(CH
2 4 0(CH 2 2
CH
3 B.41
CH
2
OCH(CH
3 2 B.42
(CH
2 2 OCH(0H 3 2 B.43
(CH
2 3 OCHi(CH 3 2 B.44
(CH
2 4 0CH(CH 3 2
CH
2
OC(CH
3 3 B.46
(CH
2 2 0C(CH 3 3 B.47
(CH
2 3 0C(CH 3 3 B.48
(CH
2 4 0C(CH 3 3 B.49
CH
2 0CF 3
(CH
2 2 0CF 3 B.51
(CH
2 3 0CF 3 B.52
(CH
2 4 0CF 3 B.53
CH
2
SCH
3 B.54
(CH
2 2
SCH
3
(CH
2 3
SCH
3 B.56
(CH
2 4
SCH
3 B.57
CH
2
SOCH
3 B.58
(CH
2 2
SOCH
3 B.59
(CH
2 3
SOCH
3
(CH
2 4
SOCH
3 B.61
CH
2
SO
2
CH
3 B.62
(CH
2 2 S0 2
CH
3 B.63
(CH
2 3 S0 2 0H 3 B.64
(CH
2 4 S0 2 gCH-A B. 65 CH 2 -CYClopropyl B.66 (CH 2 )2-cyclopropyl B. 67 (CH 2 )3-CYClopropyl B.68 (CH 2 )4-CYClopropyl B. 69 CH2-CYClopentyl B. 70 (CH 2 2-cyclopentyl B.71 (CH 2 )3-CYClopentyl B. 72 (CH 2 )4-CYClopentyl B. 73 CH 2 -CYClohexyl B.74
(CH
2 )2-CYClohexyl
(CH
2 )3-CYClohexyl B.76 (CH 2 4 -CYClohexyl ~Ac:T 0 W 0050/46043 207 No. R 3 B. 77
CHF
2 B.78
CF
3 B.79
CH
2
CHF
2
CH
2
CF
3 B.81
CHFCHF
2 B.82
CH
2
CH
2
F
B.83
CHFCH
3 B.84
CHFCF
3
CF
2
CHF
2 B.86
CF
2
CHFCF
3 B.87
CH
2 CC1 3 B.88
CF
2 CHC1 2 B.89
CF
2 CHFC1
CF
2 CHFBr B.91
CH(CF
3 2 B.92
CH(CF
3
)CH
3 B.93
CH
2 CH7CF 3 4 B.94
CH
2
CHFCH
3 It.n2Lr2CF 3 B. 96 CH 2
CH
2
CH
2
F
B.97
CH
2
CF
2
CF
2
CF
3 B.98
CH
2
CH
2
CHFCH
3 B. 99 CH 2
CH
2
CH
2
CH
2
F
B.100
CH
2 C1 B.101
CH
2
CH
2 Cl B.102
CH
2 CHC1CH 3 B.103
CH
2
CH
2
CH
2 Cl Ti1 nA f r v B. 105 B. 106 B. 107 B. 108 B. 109 B. 110 B. 111 B. 112 B. 113 B. 114 B. 115 CH2CH 2
CH
2
CH
2 C 1
CH
2 Br
CH
2
CH
2 Br
CH
2 CHBrCH 3
CH
2
CH
2
CH
2 Br
CH
2
CH
2 CHBrCH 3 CH2CH 2
CH
2
CH
2 Br
CH
2
-C
6
H
CH2-O-C 6
H
CH (CH 3
CN
CH(CH
3
)CH
2
CN
0050/46043 208 Nlo. R 3 B.116
CH
2
CH(CH
3
)CN
B.117
CH(CH
3
)CH(CH
3
)CN
B.118
CH(CH
3
(CH
2 2
CN
B.119
CH
2
CH(CH
3
)CH
2
CN
B.120 (0H 2 2
CH(CH
3
)CN
B.121
CH(CH
3
)CH(CH
3
)CH
2
CN
B.122 CH(CH 3
)CH
2
CH(CH
3
)CN
B.123
CH
2
CH(CH
3
)CH(CH
3
)CN
B.124 CH(CH3)CH(CH 3
)CH(CH
3
)CN
B.125
CH(CH
3
)(CH
2 3
CN
B.126
CH(CH
3 )N0 2 B.127
CH(CH
3
)CH
2 No 2 B.128
CH
2
CH(CH
3 )N0 2 B 129
CHIC-H
3
),CH(CH
3 )N0 2 B.130 CH(CHi 3
)(CH
2 2 No 2 B.131
CH
2 CH (CH 3
CH
2 No 2 B.132
(CH
2 2
CH(CH
3 )N0 2 B.133
CH(CH
3
)CH(CH
3
)CH
2
NO
2 B.134
CH(CH
3
)CH
2
CH(CH
3
)NQ
2 B.135 CH2CH(CH 3
)CH(CH
3 )N0 2 B.136
CH(CH
3
)CH(CH
3
)CH(CH
3 )N0 2 B.137
CH(CH
3
)(CH
2 3 N0 2 B..138
CH(CH
3
)OH
B.139
CH(CH
3
)CH
2 0H B.140
CH
2
CH(CH
3
)OH
B.141
CH(CH
3
)CH(CH
3
)OH
B.142
CH(CH
3
(CH
2 2 0H B.143
CH
2
CH(CH
3
)CH
2
OH
B.144
(CH
2 2
CH(CH
3
)OH
B.145
CH(CH
3
)CH(CH
3
)CH
2 0H B.146
CH(CH
3
)CH
2
CH(CH
3
)OH
B.147 CH2CH(CH 3
)CH(CH
3
)OH
B.148
CH(CH
3
)CH(CH
3
)CH(CH
3
)OH
B.149
CH(CH
3
)(CH
2 3 0H B.150
CH(CH
3
)OCH
3 B.151
CH(CH
3
)CH
2
OCH
3 B.152
CH
2
CH(CH
3
)OCH
3 B.153
CH(CH
3
)CH(CH
3
)OCH
3 B.154
CH(CH
3
)(CH
2 2 0CH 3 ,PT e 0050/46043 209 No.
R
B. 155 CH 2
CH(CH
3
)CH
2
OCH
3 B.156 (CH 2 2
CH(CH
3
)OCH
3 B.157 CH(CH 3
)CH(CH
3
)CH
2
OCH
3 B.158 CH(CH 3
)CH
2
CH(CH
3
)OCH
3 B.159 CH 2
CH(CH
3
)CH(CH
3
)OCH
3 B.160 CH(CH 3
)CH(CH
3
)CH(CH
3
)OCH
3 B.161 CH(CH 3
)(CH
2 3 0CH 3 B.162 CH(CH 3
)OCH
2
CH
3 B.163 CH(CH 3
)CH
2
OCH
2
CH
3 B.164 CH 2
CH(CH
3
)OCH
2
CH
3 B.165 CH(CH 3
)CH(CH
3
)OCH
2
CH
3 B.166 CH(CH 3
(CH
2 2
OCH
2
CH
3 B. 167 CH 2
CH(CH
3
)CH
2
OCH
2
CH
3 B.168 (CH 2 2
CH(CH
3
)OCH
2
CH
3 B.169 CH(CH 3
)CH(CH
3
)CH
2
OCH
2
CH
3 B.170 CH(CH 3
)CH
2
CH(CH
3
)OCH
2
CH
3 B.171 CH 2
CH(CH
3
)CH(CH
3
)OCH
2
CH
3 B.172 CH(CH 3
)CH(CH
3
)CH(CH
3
)QCH
2
CH
3 B.173 CH(CH 3
(CH
2 3
OCH
2
CH
3 B.174 CH(CH 3
)CH
2
O(CH
2 2
CH
3 B.175 CH 2
CH(CH
3
)O(CH
2 2
CH
3 B.176 CH (CH 3 CH (CH 3 )O0(CH 2 2
CH
3 B.177 CH (CH 3
(CH
2 2 0 (CH 2 2
CH
3 B.178 CH 2 CH (CH 3
CH
2 0O(CH 2 2
CH
3 B.179 (CH 2 2 CH (CH 3 )O0(CH 2 2
CH
3 B.180 CH(CH 3
)CH(CH
3
)CH
2
O(CH
2 2
CH
3 B.181 CH (CH 3
CH
2 CH (CH 3 )O0(CH 2 2
CH
3 B.182 CH 2
CH(CH
3
)CH(CH
3
)O(CH
2 2
CH
3 B.183 CH(CH 3
)CH(CH
3
)CH(CH
3
)O(CH
2 2
CH
3 B.184 CH (CH 3
(CH
2 3 0 (CH 2 2
CH
3 B.185 CH(CH 3
)OCH(CH
3 2 B.186 CH(CH 3
)CH
2
QCH(CH
3 2 B.187 CH 2
CH(CH
3
)OCH(CH
3 2 B.188 CH(CH 3
)CH(CH
3
)OCH(CH
3 2 B.189 CH(CH 3
)(CH
2 2
OCH(CH
3 2 B.190 CH 2
CH(CH
3
)CH
2
OCH(CH
3 2 B.191 (CH 2 2
CH(CH
3
)OCH(CH
3 2 B.192 CH(CH 3
)CH(CH
3
)CH
2
OCH(CH
3 2 B.193 CH(CH 3
)CH
2
CH(CH
3
)OCH(CH
3 2 0050/46043 210 N~o.
R
B. 194 CH 2
CH(CH
3
)CH(CH
3
)QCH(CH
3 2 B.195 CH(CH 3
)CH(CH
3
)CH(CH
3
)OCH(CH
3 2 B.196 CH(CH 3
)(CH
2 3
OCH(CH
3 2 B.197 CH(CH 3
)OC(CH
3 3 B.198 CH(CH 3
)CH
2
OC(CH
3 3 B.199 CH 2
CH(CH
3
)OC(CH
3 3 B.200 CH(CH 3
)CH(CH
3
)OC(CH
3 3 B.201 CH(CH 3
)(CH
2 2 0C(CH 3 3 B.202 CH 2
CH(CH
3
)CH
2
OC(CH
3 3 B.203 (CH 2 2
CH(CH
3
)OC(CH
3 3 B.204 CH(CH 3
)CH(CH
3
)CH
2
OC(CH
3 3 B.205 CH(CH 3
)CH
2
CH(CH
3
)OC(CH
3 3 B.206 CH 2
CH(CH
3
)CH(CH
3
)OC(CH
3 3 B.207 CH(CH 3
)CH(CH
3
)CH(CH
3
)OC(CH
3 3 B.208 CH(CH 3
)(CH
2 3 0C(CH 3 3 B.209 CH(CH 3
)OCF
3 B.210 CH(CH 3
)CH
2
OCF
3 B.211 CH 2
CH(CH
3
)OCF
3 B.212 CH(CH 3
)CH(CH
3
)OCF
3 B.213 CH(CH 3
)(CH
2 2 0CF 3 B.214 CH 2
CH(CH
3
)CH
2
OCF
3 B.215 (CH 2 2
CH(CH
3
)OCF
3 B.216 CH(CH 3
)CH(CH
3
)CH
2
OCF
3 B.217 CH(CH 3
)CH
2
CH(CH
3 )0CF 3 B.218 CH 2
CH(CH
3
)CH(CH
3
)OCF
3 B.219 CH(CH 3
)CH(CH
3
)CH(CH
3 )0CF 3 B.220 CH(CH 3
)(CH
2 3 0CF 3 B.221 CH(CH 3
)SCH
3 B.222 CH(CH 3
)CH
2
SCH
3 B.223 CH 2
CH(CH
3
)SCH
3 B.224 CH(CH 3
)CH(CH
3
)SCH
3 B.225 CH(CH 3
)(CH
2 2
SCH
3 B.226
CH
2
CH(CH
3
)CH
2
SCH
3 B.227 (CH 2 2
CH(CH
3
)SCH
3 B.228 CH(CH 3
)CH(CH
3
)CH
2
SCH
3 B.229 CH(CH 3
)CH
2
CH(CH
3
)SCH
3 B.230 CH 2
CH(CH
3
)CH(CH
3
)SCH
3 B.231 CH(CH 3
)CH(CH
3
)CH(CH
3
)SCH
3 B.232
CH(CH
3
)(CH
2 3
SCH
3 0050/46043 211 No.
R
B.233 CH (CH 3
SOCH
3 B.234
CH(CH
3
)CH
2
SOCH
3 B.235
CH
2
CH(CH
3
)SOCH
3 B.236
CH(CH
3
)CH(CH
3
)SOCH
3 B.237
CH(CH
3
)(CH
2 2
SOCH
3 B.238
CH
2
CH(CH
3
)CH
2
SOCH
3 B.239
(CH
2 2 C11(CH 3
)SOCH
3 B.240
CH(CH
3
)CH(CH
3
)CH
2
SOCH
3 B.241
CH(CH
3
)CH
2
CH(CH
3
)SOCH
3 B.242 CH2CH(CH 3 )CHi(CH 3
)SOCH
3 B.243 CH(CH3)CH(CH 3
)CH(CH
3
)SOCH
3 B.244
CH(CH
3
)(CH
2 3
SQCH
3 B.245
CH(CH
3
)SO
2
CH
3 B.46t CH (CH 3
)CH
2
SO
2
CH
3 B.247 CH (CH 3
)(CH
2 3 S0 2
CH
3 B.248
CH
2
CH(CH
3 )S0 2
CH
3 B.249
CH(CH
3
)CH(CH
3 )S0 2
CH
3 B.250 CH (CH 3
(CH
2 2 S0 2
CH
3 B.251
CH
2
CH(CH
3
)CH
2
SO
2
CH
3 B.252
(CH
2 2
CH(CH
3 )S0 2
CH
3 B.253
CH(CH
3
)CH(CH
3
)CH
2
SO
2
CH
3 B.254
CH(CH
3
)CH
2
CH(CH
3
)SO
2
CH
3 B.255
CH
2
CH(CH
3
)CH(CH
3
)SO
2
CH
3 B.256
CH(CH
3
)CH(CH
3
)CH(CH
3
)SO
2
CH
3 B.257 CH (CH 3
(CH
2 3 S0 2
CH
3 B.258 CH(CH 3 )-cyclopropyl B.259 CH (CH 3
CH
2 -cyclopropyl B.260 CH 2
CH(CH
3 )-cyclopropyl B.261 CH(CH 3
)CH(CH
3 )-cycloprop yl B.262 CH(CH 3 (CH2) 2 -CYClopropyl B.263 CH 2
CH(CH
3 )CH2-CYClopropyl B.264 (CH2) 2
CE(CH
3 )-cyclopropyl B.265 CH(CH 3
)CH(CH
3
)CH
2 -CYClopropyl B.266 CH(CH 3
)CH
2
CH(CH
3 )-cyclopropyl B.267 CH2CH(CH 3
)CH(CH
3 )-cyclopropyl B.268 CH(CH 3
)CH(CH
3
)CH(CH
3 )-cyclopropyl B.269 CH(CH 3
(CH
2 3 -CYClopropyl B.270 CH(CH 3 )-cyclopentyl B. 271 CH (CHA CH 2 -cyclopentyl 0050/46043 ____212 No. R B.272
CH
2
CH(CH
3 )-cyclopentyl B.273 CH(CH3)CH(CH 3 )-cyclopentyl B.274
CH(CH
3 (CH2) 2 -cyclopentyl B.275
CH
2 CH (CH 3
)CH
2 -cyclopenty.
B.276 (CH2)2CH(CH 3 )-cyclopentyl B.277 CH(CH3)CH(CH 3
)CH
2 -CYClopentyl B.278
CH(CH
3 )CH2CH(CH 3 )-cyclopentyl B.279 CH2CH(CH 3
)CH(CH
3 )-cyclopentyl B.280 CH(CH3)CH(CH 3
)CH(CH
3 )-cyclopentyl B.281
CH(CH
3 (CH2) 3 -CYClopentyl B.282
CH(CH
3 )-cyclohexyl B.283
CH(CH
3
)CH
2 -cyclohexyl B.284
CH
2 CH (CH 3 )-cyclohexyl B Ou C(H) CH (CH 3 )-cyciohexyl B.286
CH(CH
3 (CH2) 2 -cyciohexyi B. 287 CH 2 CH (CH 3
)CH
2 -cyciohexyi B.288 (CH2) 2 CH (CH 3 -cyclohexyl B.289
CH(CH
3
)CH(CH
3
)CH
2 -CYClohexyl B.290
CH(CH
3
)CH
2
CH(CH
3 )-cyclohexyl B.291 CH2CH(CH 3
)CH(CH
3 )-cyclohexyl B. 292 CH(CH 3
)CH(CH
3
)CH(CH
3 )-cyclohexyi B.293
CH(CH
3
(CH
2 3 -cyclohexyl B.294
CH(CH
3
)CHF
2 B.295
CF(CH
3
)CHF
2 B.296
CH(CH
3
)CH
2
F
B.297
CF(CH
3
)CH
3 B.298
CF(CH
3
)CF
3 B.299
CH(CH
3 )CC1 3 B.300
CH(CH
3
)CF
3 B.301
CH(CH
3
)CH
2
CF
3 B.302
CH
2
CH(CH
3
)CF
3 B.303
CH(CH
3
)CH(CH
3
)CF
3 B.304
CH(CH
3
)CF
2
CF
3 B.305
CH(CH
3 )Br B.306
CH(CH
3
)CH
2 Br B.307
CH(CH
3
)(CH
2 2 Br B.308
CH(CH
3
)(CH
2 3 Br B.309
CH(CH
3 )Cl B.310
CH(CH
3
)CH
2 Cl 0050/46043 ____213 No. R 3 B.311
CH(CH
3
)(CH
2 2 Cl B.312
CH(CH
3
)(CH
2 3 Cl B.313
CH(CH
3
)QCF
3 B.314
CH(CH
3
)CH
2
OCF
3 B.315
CH(CH
3
)(CH
2 2 0CF 3 B.316
CH(CH
3
)(CH
2 3 0CF 3 B.317 CH(CH 3
)F
B.318 CH(CH 3
)CH
2
F
B.319 CH(CH 3
)(CH
2 2
F
B.320 CH(CH 3
)(CH
2 3
F
B.321 CH(CH 3 )-phenyl B.322 CH(CH 3
)CH
2 -phenyl B.323 CH 2
CH(CH
3 )-phenyl B. 32A C H(CH 3
)CH(CH
3 )-phenyl B.325 CH(CH 3
(CH
2 2 -phenyl B.326 CH 2 CH (CH 3
)CH
2 -phenyl B.327 (CH 2 2
CH(CH
3 )-phenyl B.328 CH(CH 3
)CH(CH
3
)CH
2 -phenyl B.329 CH(CH 3
)CH
2
CH(CH
3 )-phenyl B.330 CH 2
CH(CH
3
)CH(CH
3 )-phenyl B.331 CH(CH 3
)CH(CH
3
)CH(CH
3 )-phenyl B.332 CH(CH 3
(CH
2 3 -phenyl B. 333 2-F-C 6
H
4
-CH
2 B.334 3-F-C 6
H
4
-CH
2 B.335 4-F-C 6
H
4
-CH
2 B.336 2,3-F 2
-C
6
H
3
-CH
2 B.337 2,4-F 2
-C
6
H
3
-CH
2 B.338 2 ,5-F 2 -0 6
H
3
-CH
2 B.339 2, 6-F 2 6
H
3
-CH
2 B.340 3,4-F 2
-C
6
H
3
-CH
2 B.341 3,5-F 2
-C
6
H
3
-CH
2 B.342 2-Cl-C 6 i 4
-CH
2 B.343 3-C1-C 6
H
4
-CH
2 B.344 4-Cl-C 6
H
4
-CH
2 B. 345 2, 3-C 2
-C
6
H
3
-CH
2 B.346 2,4-Cl 2
-C
6
H
3
-CH
2 B. 347 2, 5-C1 2
-C
6
H
3
-CH
2 B.348 2, 6-C1 2
-C
6
H
3
-CH
2 B.349 3,4-Cl 2
-C
6
H
3
-CH
2 1,1 0050/46043 214 No.
R
B.350 3,5-C1 2
-CH
3
-CH
2 B.351 2,3,4-Cl 3
-C
6
H
2
-CH
2 B.352 2,3, 5-C1 3
-C
6
H
2
-CH
2 B.353 2,3, 6-Cl 3
-C
6
H
2
-CH
2 B.354 2,4,5-C 3
-C
6
H
2
-CH
2 B. 355 2, 4, 6-C1 3
-C
6
H
2
-CH
2 B.356 3,4,5-C 3
-C
6
H
2
-CH
2 B. 357 2-Br-C 6
H
4
-CH
2 B. 358 3-Br-C 6
H
4
-CH
2 B .359 4-Br-C 6
H
4
-CH
2 B. 360 2, 3-Br 2
-C
6
H
3
-CH
2 B.361 2,4-Br 2
-C
6
H
3
-CH
2 B.362 2, 5-Br 2
-C
6
H
3
-CH
2 B. 363 2, 6-Br 2
-C
6
H
3
-CH
2 B.364 3,4-Br 2
-C
6
H
3
-CH
2 B.365 3, 5-Br 2
-C
6
H
3
-CH
2 B.366 2-F, 3-C1-C 6
H
3
-CH
2 B.367 2-F, 4-C1-C 6
H
3
-CH
2 B.368 2-F, 5-Cl-C 6
H
3
-CH
2 B.369 2-F, 3-Br-C 6
H
3
-CH
2 B.370 2-F, 4-Br-C 6
H
3
-CH
2 B.371 2-F, 5-Br-C 6
H
3
-CH
2 B.372 2-Cl, 3-F-C 6
H
3
-CH
2 B.373 2-Cl, 4-F-C 6
H
3
-CH
2 B.374 2-Cl, 5-F-C 6
H
3
-CH
2 B.375 2-Cl, 3-Br-C 6
H
3
-CH
2 B.376 2-Cl, 4-Br-C 6
H
3
-CH
2 B.377 2-Cl, 5-Br-C 6
H
3
-CH
2 B.378 2-Br, 3-F-C 6
H
3
-CH
2 B.379 2-Br, 4-F-C 6
H
3
-CH
2 B.380 2-Br, 5-F-C 6
H
3
-CH
2 B.381 2-Br, 3-Cl-C 6
H
3
-CH
2 B.382 2-Br, 4-Cl-C 6
H
3
-CH
2 B.383 2-Br, 5-Cl-C 6
H
3
-CH
2 B.384 4-Cl, 3,5-Br 2
-C
6
H
2
-CH
2 B.385 2-CN-C 6
H
4
-CH
2 B. 386 3-CN-C 6
H
4
-CH
2 B.387 14-CN-C 6
H
4
-CH
2 B.388 I2-N0 2
-C
6
H
4
-CH
2 0050/46043 215 No.
R
B.389 3-N0 2
-C
6
H
4
-CH
2 B.390 4-N0 2
-C
6
H
4
-CH
2 B. 391 2-CH 3
-C
6
H
4
-CH
2 B. 392 3-CH 3
-C
6
H
4
-CH
2 B.393 4-CH 3
-C
6
H
4
-CH
2 B.394 2,3-(CH 3 2
-C
6
H
3
-CH
2 B.395 2,4-(CH 3 2
-C
6
H
3
-CH
2 B.396 2,5-(CH 3 2
-C
6
H
3
-CH
2 B.397 2,6-(CH 3 2
-C
6
H
3
-CH
2 B.398 3,4-(CH 3 2
-C
6
H
3
-CH
2 B.399 3,5-(CH 3 2
-C
6
H
3
-CH
2 B.400 2-CH 2
CH
3
-C
6
H
4
-CH
2 B.401 3-CH 2
CH
3
-C
6
H
4
-CH
2 B.402 4-CH 2
CH
3
-C
6
H
4
-CH
2 B.403 2-CH(CH 3 2
-C
6
H
4
-CH
2 B.404 3-CH(CH 3 2
-C
6
H
4
-CH
2 B.405 4-CH(CH 3 2
-C
6
H
4
-CH
2 B.406 3-C (CHA) 3
-C
6
H
4
-CH
2 B.407 4-C (CH 3 3
-C
6
H
4
-CH
2 B.408 2-C 6
H
5
-C
6
H
4
-CH
2 B.409 3-C 6
H
5
-C
6
H
4
-CH
2 B.410 4-C 6
H
5
-C
6
H
4
-CH
2 B.411 2-OCH 3
-C
6
H
4
-CH
2 B. 412 3-OCH 3
-C
6
H
4
-CH
2 B. 413 4-OCH 3
-C
6
H
4
-CH
2 B.414 2, 3- (OCH 3 2
-C
6
H
3
-CH
2 B.415 2,4-(OCH 3 2
-C
6
H
3
-CH
2 B.416 2,5-(OCH 3 2
-C
6
H
3
-CH
2 B.417 2,6-(OCH 3 2
-C
6
H
3
-CH
2 B.418 3,4-(OCH 3 2
-C
6
H
3
-CH
2 B.419 3,5-(OCH 3 2
-C
6
H
3
-CH
2 B.420 3,4,5-(OCH 3 3
-C
6
H
2
-CH
2 B. 421 2-OCH 2
CH
3
-C
6
H
4
-CH
2 B.422 3-OCH 2
CH
3
-C
6
H
4
-CH
2 B. 423 4-OCH 2
CH
3
-C
6
H
4
-CH
2 B.424 2-0O(CH 2 2
CH
3
-C
6
H
4
-CH
2 B.425 3-O(CH 2 2
CH
3
-C
6
H
4
-CH
2 B.426 4-0 (CH 2 2
CH
3
-C
6
H
4
-CH
2 B.427 2-OCH (OH 3 2
-C
6
H
4
-CH
2
T
A; 0050/46043 216 No. R B.428 3-OCH(CH 3 2
-C
6
H
4
-CH
2 B.429 4-OCH(CH 3 2
-C
6
H
4
-CH
2 B.430 3-OC(CH 3 3
-C
6
H
4
-CH
2 B.431 4-OC(CH 3 3
-C
6
H
4
-CH
2 B.432 2-OCH 2
CH=CH
2
-C
6
H
4
-CH
2 B.433 3-OCH 2
CH=CH
2
-C
6
H
4
-CH
2 B.434 4 -OCH 2
CH=CH
2
-C
6
H
4
-CH
2 B.435 2-CF 3
-C
6
H
4
-CH
2 B.436 3-CF 3
-C
6
H
4
-CH
2 B.437 4-CF 3
-C
6
H
4
-CH
2 B. 438 2-CO 2
CH
3
-C
6
H
4
-CH
2 B.439 3-CO 2
CH
3
-C
6
H
4
-CH
2 B.440 4-CO 2
CH
3
-C
6
H
4
-CH
2 2-CO 2
CH
2
CH
3
-C
6
H
4
-CH
2 B.442 3-CO 2
CH
2
CH
3
-C
6
H
4
-CH
2 B.443 4-CO 2
CH
2
CH
3
-C
6
H
4
-CH
2 B.444 2-CONH 2
-C
6
H
4
-CH
2 B.445 3-CONH 2
-C
6
H
4
-CH
2 B.446 4-CONH 2
-C
6
H
4
-CH
2 B.447 2-CON(CH 3 2
-C
6
H
4
-CH
2 B.448 3-CON(CH 3 2
-C
6
H
4
-CH
2 B.449 4-CON(CH 3 2
-C
6
H
4
-CH
2 B. 450 2-CONHCH 3
-C
6
H
4
-CH
2 B. 451 3-CONHCH 3
-C
6
H
4
-CH
2 B. 452 4-CONHCH 3
-C
6
H
4
-CH
2 B.453 2-NH 2
-C
6
H
4
-CH
2 B.454 3-NH 2
-C
6
H
4
-CH
2 B.455 4-NH 2
-C
6
H
4
-CH
2 B.456 2-N(CH 3 2
-C
6
H
4
-CH
2 B.457 3-N(CH 3 2
-C
6
H
4
-CH
2 B.458 4-N (CH 3 2
-C
6
H
4
-CH
2 B. 459 2-NHCH 3
-C
6
H
4
-CH
2 B.460 3-NHCH 3
-C
6
H
4
-CH
2 B. 461 4-NHCH 3
-C
6
H
4
-CH
2 B. 462 2-CSNH 2
-C
6
H
4
-CH
2 B.463 3-CSNH 2
-C
6
H
4
-CH
2 B. 464 4-CSNH 2
-C
6
H
4
-CH
2 B.465 2-SCH 3
-C
6
H
4
-CH
2 B.466 3-SCH 3
-C
6
H
4
-CH
2 0050/46043 ____217 No. R B. 467 4-SCH 3
-C
6
H
4
-CH
2 B. 468 2-SOCH 3
-C
6
H
4
-CH
2 B.469 3-SOCH 3
-C
6
H
4
-CH
2 B.470 4-SOCH 3
-C
6
H
4
-CH
2 B.471 2-SO2CH 3
-C
6
H
4
-CH
2 B.472 3-SO2CH 3
-C
6
H
4
-CH
2 B. 473 4-SO2CH 3
-C
6
H
4
-CH
2 B.474 2-OCF 3
-C
6
H
4
-CH
2 B. 475 3-OCF 3
-C
6
H
4
-CH
2 B.476 4-OCF 3
-C
6
H
4
-CH
2 B.477 2-OCHF 2
-C
6
H
4
-CH
2 B. 478 3-OCHF 2
-C
6
H
4
-CH
2 B.479 4-OCHF 2
-C
6
H
4
-CH
2 B.480 3- F 3 t V-CF 3
H-CH
2 B.481 2-CH 2
CH
2
F-C
6
H
4
-CH
2 B. 482 3-CH 2
CH
2
F-C
6
H
4
-CH
2 B. 483 4-CH 2
CH
2
F-C
6
H
4
-CH
2 B. 484 2-CH 2
CF
3
-C
6
H
4
-CH
2 B. 485 3-CH 2
CF
3
-C
6
H
4
-CH
2 B. 486 4-CH 2
CF
3
-C
6
H
4
-CH
2 B. 487 2-CF 2
CHF
2
-C
6
H
4
-CH
2 B.488 3-CF 2
CHF
2
-C
6
H
4
-CH
2 B. 489 4-CF 2
CHF
2
-C
6
H
4
-CH
2 B. 490 2-CHF 2
-C
6
H
4
-CH
2 B. 491 3-CHF 2
-C
6
H
4
-CH
2 B. 492 4-CHF 2
-C
6
H
4
-CH
2 B. 493 naphthalen-1-yl-CH 2 B. 494 naphthalen-2-Yl-CH 2 B. 495 pyridin-2-yl-CH 2 B. 496 pyridin-3-yl-CH 2 B. 497 pyridin-4-yl-CH 2 B. 498 5-CH3-pyridin-2-yl-CH 2 B. 499 6-CH3-pyridin-2-yl-CH 2 B. 500 5-CH 3 -pyridin-3-yl-CH 2 B. 501 6-CH3-pyridin-3 _yl-CH 2 B. 502 5-OCH3-pyridin-2-yl-CH 2 B. 503 6-OCH3-pyridin-2-yl-CH 2 B. 504 5-OCH3-pyridirl-3-yl-CH 2 6-OCH3-pyridin-3-Yl-CH 2 0050/46043 218 No.
R
B.506 4-Cl-pyridin-2-yl-CH 2 B.507 5-Cl-pyridin-2-yl-CH 2 B.508 6-Cl-pyridin-2-yl-CH 2 B. 509 2-C1--pyridin-3-yl-CH 2 B.510 5-Cl--pyridin-3-yl-CH 2 B.511 6-C1--pyridin-3-_yl-CH 2 B.512 2-Cl-pyridin-4-yl-CH 2 B.513 3, 5-Cl-pyridin-2-yl-CH 2 B.514 pyrimidin-2-yl-CH 2 B. 515 4-C 1-pyrimidin-2 -yl-CH 2 B .516 5-Cl-pyrimidin-2-yl-CH 2 B.517 4-CH 3 -pyrimidin-2-yl-CH 2 B. 518 5-CH 3 -pyrimidin-2-yl-CHi 2 B. 519 4-OCH 3 -pyrimidin-2-yi-CH 2 B. 520 5-OCH3-pyrimidin-2-yl-CH 2 B. 521 4-OCH2CH 3 -pyrimidin-2-yl-CH 2 B.522 5-OCH 2
CH
3 -pyrimidin-2-yl-CH 2 B. 523 pyrimidin-4-yl-CH 2 B.524 2-Cl-pyrimidin-4-yl-CH 2 B. 525 6-C 1-pyrimidin-4-yl-C 2 B.526 2, 6-C1 2 -pyrimidin-4-yl-CH 2 B.527 2-CH 3 -pyrimidin-4-yl-CH 2 B. 528 6-CH 3 -pyrimidin-4-yl-CH 2 B. 529 2-OCH 3 -pyrimidin-4-yl-CH 2 B. 530 6-OCH 3 -pyrimidin-4-yl-CH 2 B. 531 2-OCH 2
CH
3 -pyrimidin-4-yl-CH 2 B. 532 6-OCH 2
CH
3 -pyrimidin-4-yl-CH 2 B.533 pyrimidin-5-yl-CH 2 B.534 2-Cl-pyrimidin-5-yl-CH 2 B. 535 2-CH 3 -pyrimidin-5-yl-CH 2 B.536 2-OCH 3 -pyrimidin-5-yl-CH 2 B. 537 2-OCH 2
CH
3 -pyrimidin-5-yl-CH 2 B .538 furan-2-yl-CH 2 B.539 4-Br-furan-2-Yl-CH 2 B. 540 4-Cl-furan-2-Yl-CH 2 B. 541 4-CIN-furan-2-y1-CH 2 B.542 4-CH 3 -furan-2-yl-CH 2 B .543 5-Br-furan-2-yl-CH 2 B.544 5-Cl-furan-2-yl-CH 2 0050/46043 219 No.
R
B. 545 5-CN-furan-2-Yl-CH 2 B.546 5-CH 3 -furan-2-yl-CH 2 B.547 furan-3-yl-CH 2 B.548 5-Br-furan-3-yl-CH 2 B.549 5-C1-furan-3-yl-CH 2 B. 550 5-CN-furan-3-yl-CH 2 B.551 5-CH 3 -furan-3-yl-CH 2 B. 552 thien-2-yl-CH 2 B. 553 4-Br-thien-2-yl-CH 2 B. 554 4-Cl-thien-2-yl-CH 2 B. 555 4-CN-thien-2-yl-CHi 2 B. 556 4-CH 3 -thien-2-yl-CH 2 B. 557 5-Br-thien-2-yl-CH 2 B. 558 5-Cl-thien-2-y-CH 2 B. 559 5-CN-thien-2-yl-CH 2 B.560 5-CH 3 -thien-2-yl-CH 2 B.561 thien-3-yl-CH 2 B.562 5-Br-thien-3-yl-CH 2 B.563 5-C1-thien-3-yl-CH 2 B. 564 5-CN-thien-3-yl-CH 2 B.565 5-CH 3 -thien-3-yl-CH 2 B.566 oxazol-2-yl-CH 2 B. 567 4-Br-oxazol-2-yl-CH 2 B. 568 4-C1-oxazol-2-yl-CH 2 B.569 4-CN-oxazol-2-yl-CH 2 B. 570 4-CH 3 -oxazol-2-yl-CHi 2 B. 571 5-Br-oxazol-2-yl-CH 2 B. 572 5-Cl-oxazol-2-Yl-H 2 B. 573 5-CN-oxazol-2-Yl-CH 2 B. 574 5-CH 3 -oxaZOl-2-yl-CH 2 B. 575 oxazol-4-yl-CH 2 B. 576 2-Br-oxazol-4-yl-CH 2 B. 577 2-C1-oxazol-4-yl-CH 2 B. 578 2-CN-oxazol-4-yl-CH 2 B. 579 2-CH 3 -oxazol-4-yl-CH 2 B. 580 2-C 6
H
5 -oxazol-4-yl-CH 2 B.581 5-Br-oxazol-4-yl-CH 2 B. 582 5-Cl-oxazol-4-yl-CH 2 B. 583 5-CN-oxazol-4-yl-CH 2 0050/46043 220 No. R 3 B. 584 5-CH 3 -oxazol-4-yl-CH 2 B.585 oxazol-5-yl-CH 2 B. 586 4-Br-oxazol-5-yl-CH 2 B. 587 4-C1-oxazol-5-yl-CH 2 B. 588 4-CN-oxazol-5-yl-CH 2 B. 589 4-CH 3 -oxazol-5-yl-CH 2 B. 590 2-Br-oxazol-5-yl-CH 2 B. 591 2-Cl-oxazol-5-yl-CH 2 B.592 2-CN-oxazol-5-yl-CH 2 B. 593 2-CH 3 -oxazol-5-yl-CH 2 B. 594 isoxazol-3-yl-CH 2 B. 595 4-Br--isoxazol-3-yl-CH 2 B. 596 4-Cl-isoxazol-3-Yl-CH 2 4-CN-isoxazo'i-3-Yi-CH 2 B.598 4-CH 3 -isoxazol-3-yl-CH 2 B. 599 5-Br-isoxazol-3-yl-CH 2 B. 600 5-Cl-isoxazol-3-yl-CH 2 B. 601 5-CN-isoxazol-3-yl-CH 2 B. 602 5-CH 3 -isoxazol-3-yl-CH 2 B. 603 isoxazol-4-yl-CH 2 B. 604 3-Br-isoxazol-4-yl-CH 2 B. 605 3-Cl-isoxazol-4-yl-CH 2 B. 606 3-CN-isoxazol-4-yl-CH 2 B. 607 3-CH 3 -isoxazol-4-yl-CH 2 B. 608 5-Br-isoxazol-4-yl-CH 2 B. 609 5-Cl-isoxazol-4-yl-CH 2 B. 610 5-CN-isoxazol-4-yl-CH 2 B.611 5-CH 3 -isoxazol-4-yl-CH 2 B.612 3, 5- (CH 3 2 -isoxazol-4-yl-CH 2 B. 613 isoxazol-5-yl-CH 2 B. 614 3-Br-isoxazol-5-Yl-CH 2 B. 615 3-Cl-isoxazol-5-yl-CH 2 B. 616 3-CI%-isoxazol-5-yl-CH 2 B. 617 3-CH 3 -isoxazol-5-yl-CH 2 B. 618 3-C 6
H
5 -isoxazol-5-yl-CH 2 B. 619 4-Cl, 3-C 6
H
5 -isoxazol-5-yl-CH 2 B. 620 4-Br, 3-C 6
H
5 -isoxazol-5-yl-CH 2 B. 621 4-Br-isoxazol-5-yl-CH 2 B. 622 4-Cl-isoxazol-5-yl-CH 2 0050/46043 221 No. R 3 B. 623 4-CN-isoxazol-5-yl-CH 2 B. 624 4-CH 3 -isoxazol-5-yl-CH 2 B. 625 thiazol-2-yl-CH 2 B.626 4-Br-thiazol-2-yl-CH 2 B. 627 4-Cl-thiazol-2-yl-CH 2 B. 628 4-CN-thiazol-2-yl-CH 2 B.629 4-CH 3 -thiazol-2-Yl-CH 2 B. 630 5-Br-thiazol-2-yl-CH 2 B. 631 5-Cl-thiazol-2-yl-CH 2 B. 632 5-CI-thiazol-2-yl-CH 2 B. 633 5-CH 3 -thiazol-2-yl-CH 2 B. 634 thiazol-4-yl-CH 2 B.635 2-Br-thiazol-4-yl-CH 2 B662-CI-thiazol-4-yl-CH 2 B. 637 2-CN-thiazol-4-yl-CH 2 B. 638 2-CH 3 -thiazol-4-yl-CH 2 B.639 5-Br-thiazol-4-yl-CH 2 B. 640 5-C1-thiazol-4-Yl-CH 2 B. 641 5-CN-thiazol-4-yl-CH 2 B. 642 5-CH 3 -thiazol-4-yl-CH 2 B.643 thiazol-5-yl-CH 2 B.644 4-Br-thiazol-5-yl-CH 2 B.645 4-C1-thiazol-5-yl-CH 2 B.646 4-CN-thiazol-5-yl-CH 2 B. 647 4-CH 3 -thiazol-5-yl-CH 2 B. 648 2-Br-thiazol-5-yl-CH 2 B. 649 2-Cl-thiazol-5-yl-CH 2 B. 650 2-CN-thiazol-5-yl-CH 2 B. 651 2-CH 3 -thiazol-5-yl-CH 2 B.652 isothiazol-3-yl-CH 2 B. 653 4-Br-isothiazol-3-yl-CH 2 B. 654 4-Cl-isothiazol-3-yl-CH 2 B. 655 4-CN-isothiazol-3-yl-CH 2 B. 656 4-CH3-isothiazol-3-yl-CH 2 B. 657 5-Br-isothiazol-3-yl-CH 2 B.658 5-C 1-isothiazol-3-yl-CH 2 B. 659 5-CN-isothiazol-3-yl-CH 2 B. 660 5-CH3-isothiazol-3-yl-CH 2 B.661 isothiazol-4-yl-CH 2 0050/46043 222 No. R 3 B. 662 3-Br-isothiazol-4-yl-CH 2 B. 663 3-Cl-isothiazol-4-yl-CH 2 B. 664 3-CN-isothiazol-4-yl-CH 2 B.665 3-CH 3 -isothiazol-4-yl-CH 2 B. 666 5-Br-isothiazol-4-yl-CH 2 B. 667 5-Cl-isothiazol-4-yl-CH 2 B. 668 5-CN-isothiazol-4-yl-CH 2 B.669 5-CH3-isothiazol-4-yl-CH 2 B. 670 3, 5- (CH 3 2-isothiazol-4-yl-CH 2 B.671 isothiazol-5-yl-CH 2 B. 672 3-Br-isothiazol-5-yl-CH 2 B. 673 3-Cl-isothiazol-5-Yl-CH 2 B. 674 3-CN-isothiazol-5-yl-CH 2 B67 5 3-CH 3 -isothiazol-5-yl-CH 2 B.676 4-Br-isothiazol-5-yl-CH 2 B. 677 4-C1-isothiazol-5-yl-CH 2 B. 678 4-CN-isothiazol-5-yl-CH 2 B. 679 4-CH 3 -isothiazol-5-yl-CH 2 B.680 imidazol-2-yl-CH 2 B.681 1-Cl-imidazol-2-yl-CH 2 B. 682 1-Br-imidazol-2-yl-CH 2 B.683 1-CN-imidazol-2-yl-CH 2 B. 684 I-CH-imidazol-2-yl-CH 2 B.685 4-C 1-imidazol-2-yl-CH 2 B.686 4-Br-imidazol-2-yl-CH 2 B.687 4-CN-imidazol-2-Yl-CH 2 B. 688 4-CH 3 -imidazol-2-yl-CH 2 B.689 1-CH 3 5-C1-imidazol-2-yl-CH 2 B. 690 1,4-(CH 3 )2-imidazol-2-yl-CH 2 B. 691 1, 5-(CH 3 2 -imidazol-2-yl-CH 2 B. 692 imidazol-4-yl-CH 2 B. 693 2-C1-imidazol-4-Yl-CH 2 B. 694 2-Br-imidazol-4-yl-CH 2 B. 695 2-CN-imidazol-4-yl-CH 2 B.696 1-CH 3 -imidazol-4-yl-CH 2 B. 697 2-CH 3 -imidazol-4-yl-CH 2 B. 698 5-Cl-imidazol-4-yl-CH 2 B. 699 5-Br-imidazol-4-yl-CH 2 B. 700 5-CN-imidazol-4-yl-CH 2 ioA V-r 0050/46043 223 No. R 3 B. 701 5-CH3-imidazol-4-yl-CH 2 B.702 1-CH 3 5-C 1-imidazol-4-yl-CH 2 B.703 l, 2 -(CH3)2-imidazol-4-yl-CH 2 B.704 lIS-(CH3)2-imidazol-4-yl.CH 2 B.705 pyrazol-3-yl-CH 2 B. 706 5-Br-pyrazol-3-yl-CH 2 B. 707 5-Cl-pyrazol-3-yl-CH 2 B. 708 5-CN-pyrazol-3-yl-CH 2 B. 709 5-CH3-pyrazol-3-yl-CH 2 B. 710 l-C6H5-pyrazol-3-yl-CH 2 B. 711 4- Br-pyrazol-3-yl-CH 2 B. 712 4 -C1-pyrazol-3-yl-CH 2 B. 713 4-CN-pyrazol-3-yl-CH 2 B. 714 4-CH 3 -Pyrazo-3=-j
YL
B. 715 1-CH3-pyrazol-3-yl-CH 2 B.716 l, 4 -(CH3)2-pyrazol-3-yl-CH 2 B. 717 l,5-(CH3)2-pyrazol-3-yl-CH 2 B.718 1-CH 3 4 -Cl-pyrazol-3-yl-CH 2 B. 719 1-CH 3 5-Cl-pyrazol-3-yl-CH 2 B.720 pyrazol-4-yl-CH 2 B. 721 3-Br-pyrazol-4-yl-CH 2 B. 722 '3-Cl-pyrazol-4-yl-CH 2 B. 723 3-CN-pyrazol-4-yl-CH 2 B. 724 3-CH3-pyrazol-4-yl-CH 2 B. 725 1-CH3-pyrazol-4-yl-CH 2 B. 726 1, 5 -(CH3) 2 -pyrazol-4-yl-CH 2 B.727 l, 3 -(CH3)2-pyrazol-4-yl-CH 2 B. 728 1-CH 3 3-C1-pyrazol-4-yl-CH 2 B. 729 1-CH 3 5-C1-pyrazol-4-yl-CH 2 B. 730 pyrazol-5-yl-CH 2 B. 731 3-Br-pyrazol-5-yl-CH 2 B. 732 3 -Cl-pyrazol-5-yl-CH 2 B. 733 3-CN-pyrazol-5-yl-CH 2 B.734 3-CH 3 -pyrazol-5-yl-CH 2 B.735 l-CH3-pyrazol-5-yl-CH 2 B. 736 4-Br-pyrazol-5-yl-CH 2 B. 737 4-Cl-pyrazol-5-Yl-CH 2 B. 738 4-CN-pyrazol-5-yl-CH 2 r B. 739 4 -CH3-pyrazol-5-yl-CH 2 4/1 Th 0050/46043 224 No. R 3 B.740 5-CH 3 2, 4-thiadiazol-3-yl-CH=CH 741 5-CF 3 2, 4-thiadiazol-3-yl-CH=CH B.742 5-OCH 3 2, 4 -thiadiazol-3-yl-CH=CH B.743 5-Cl-i, 2, 4-thiadiazol-3-yl-CH=CH B.744 5-CH (CH3) 2-1, 2, 4-thiadiazol-3-yl-CH=CH B.745 pyrrol-2-yl-CH=CH B. 746 4 -Cl-pyrrol-2-yl--CH=CH B. 747 4-Br-pyrrol-2-yl-CH=CH B. 748 4-CH3-pyrrol-2-yl-CH=CH B.749 4-C6H5-pyrrol-2-yl-CH=CH B. 750 benzimidazol-2-yl-CH=CH B. 751 quinolin-2-yl-CH=CH B.752 2-F-C 6
H
4
-CH=C(CH
3 B.753 3-F-C 6
H
4 -CH=C (CH 3 B744FCH-HCC3 B. 754 2,4-F-C 6 H-CH=C (CH 3 B. 755 2, 3-F 2
-C
6
H
3 -CH=C (CH 3 B.757 2, 4-F 2
-C
6
H
3 -CH=C (CH 3 25B.758 2, 5-F 2
-C
6
H
3 -CH=C (CH 3 25B.759 2,6-F 2
C
6
H
3
-CH=C(CH
3 B.760 3, 4-F 2
-C
6
H
3 -CH=C (CH 3 B.761 3, -F-C 6
H-CH=C(CH
3 30B.762 2-Cl-C 6
H
4 -CH=C (CH 3 30B.763 4-Cl-C 6
H
4
-CH=C(CH
3 B.764 4,-ClCH-CHc
CH
3 B.765 2, 3-C1 2
-C
6
H
3 -CH=C (CH 3 35B.765 2, 4-C1 2
-C
6
H
3 -CH=C (CH 3 B.767 2, 5-C1 2
-C
6
H
3 -CH=C (CH 3 B.767 2, 6-C12-C 6
H
3 -CH=C (CH 3 B.769 3, 4-C12-C 6
H
3
-CH=C(CH
3 40B.77 769 3, 5-C 2
-C
6 H-CH=C (CH 3 B.772 2, 3, 4-C1 3
-C
6
H
2 -CH=C (CH 3 40B.773 2,3,5-C1 3
-C
6
H
2
-CH=C(CH
3 B. 772 2,34, 6-C1 3
-C
6
H
2 -CH=C (CH 3 45B.773 3,4,5-C1 3
-C
6
H
2
-CH=C(CH
3 B.776 2-Br-C 6
H
4 -CH=C (CH 3 B. 777 3-Br-C 6
H
4 -CH=C (CH 3 0050/46043 225 No. R 3 B.778 4-Br-C 6
H
4 -CH=C (CH 3 B.779 2,3-Br 2
-C
6
H
3
-CH=C(CH
3 B.780 2, 4-Br 2
-C
6
H
3 -CH=C (CH 3 B. 781 2, 5-Br 2
-C
6
H
3 -CH=C (CH 3 B.782 2, 6-Br 2
-C
6
H
3 -CH=C (CH 3 B.783 3, 4-Br 2
-C
6
H
3 -CH=C (CH 3 10B.784 3, 5-Br 2
-C
6
H
3 -CH=C (CH 3 108 -,3C-CH-HCC3 B.786 2-F, 4-C1-C 6
H
3
-CH=C(CH
3 B.787 2-F, 4-Cl-C 6
H
3
-CH=C(CH
3 B.788 2-F, 5-C1-C 6
H
3
-CH=C(CH
3 15B.789 2-F, 3-Br-C 6
H
3
-CH=C(CH
3 15B.790 2-F, 4-Br-C 6
H
3
-CH=C(CH
3 B7 91 2-F, 5-r-C 6
H
3
-CH=C(CH
3 B.792 2-Cl, 3-F-C 6
H
3
-CH=C(CH
3 20B.792 2-Cl, 4-F-C 6
H
3
-CH=C(CH
3 20B.794 2-Cl, 5-F-C 6
H
3
-CH=C(CH
3 B.795 2-Cl, 3-Br-C 6
H
3
-CH=C(CH
3 B.796 2-Cl, 4-Br-C 6
H
3
-CH=C(CH
3 25B.797 2-Cl, 5-Br-C 6
H
3
-CH=C(CH
3 25B.798 2-Br, 4-F-C 6
H
3
-CH=C(CH
3 B.799 2-Br, 4-F-C 6
H
3
-CH=C(CH
3 B.800 2-Br, 5-F-C 6
H
3
-CH=C(CH
3 B.801 2-Br, 3-Cl-C 6
H
3
-CH=C(CH
3 30B.802 2-Br, 4-Cl-C 6
H
3
-CH=C(CH
3 B.803 4-Cl, 3,5-Br 2
-C
6
H
2
-CH=C(CH
3 B.804 2-CN-C 6
H
4 -CH=C (CH 3 B. 805 3-CN-C 6
H
4
-CH=C(CH
3 B.806 4-CN-C 6
H
4
-CH=C(CH
3 B. 807 2-N0 2
-C
6
H
4 -CH=C (CH 3 B.808 3-N0 2
-C
6
H
4 -CH=C (CH 3 B. 809 4-N0 2
-C
6
H
4 -CH=C (CH 3 B.810 2-CH 3
-C
6
H
4
-CH=C(CH
3 B. 811 3-CH 3
-C
6 1 4 -CH=C (CH 3 B. 812 4-CH 3
-C
6
H
4
-CH=C(CH
3 B.813 2,3-(CH 3 2
-C
6
H
3
-CH=C(CH
3 45B.814 2,4-(CH 3 2
-C
6
H
3
CH=C(CH
3 4 51 5 H 2 C H 3 C C 3 B.816 2,5-(CH 3 2
-C
6
H
3
-CH=C(CH
3 0050/46043 226 No. R 3 B.817 3,4-(CH 3 2
-C
6
H
3
-CH=C(CH
3 B.818 3,5-(CH 3 2
-C
6
H
3
-CH=C(CH
3 B.819 2-CH 2
CH
3
C
6
H
4
-CH=C(CH
3 B.820 3-CH 2
CH
3
-C
6
H
4
-CH=C(CH
3 B. 821 4-CH 2
CH
3
-C
6
H
4 -CH=C (CH 3 B.822 2-CH(CH 3 2
-C
6
H
4
-CH=C(CH
3 10B.823 3-CH(CH 3 2
-C
6
H
4
-CH=C(CH
3 1 02 H H 2 6 4 C C 3 B.825 4-C(CH 3 )3-C 6
H
4
-CH=C(CH
3 B.826 4-C (CH 3 3
-C
6
H
4 -CH=C (CH 3 B.826 2-C(CH-C 6
H
4 -CH=C (CH 3 15B.828 2-C 6
H
5
-C
6
H
4 -CH=C (CH 3 15B.828 34-C 6
H
5
-C
6
H
4 -CH=C (CH 3 B.829 -C 6 H3-C 6
H
4
-CH=C(CH
3 B. 830 3-OCH 3
-C
6
H
4 -CH=C (CH 3 20B.831 3-OCH 3
-C
6
H
4 -CH=C (CH 3 20B.833 4,-OCH 3 6
H
4
-CH=C(CH
3 B.833 2,3-(OCH 3 2
-C
6 F 3
-CH=C(CH
3 B.834 2,4-(OCH 3 2
-C
6
H
3
-CH=C(CH
3 25B.836 2,6-(OCH 3 2
-C
6
H
3
-CH=C(CH
3 25B.837 2,6-(QCH 3 2
-C
6
H
3 -CH=C(C 3 B.838 3,5- (OCH 3 2
-C
6
H
3 -CH=C (CH 3 B.839 3,45-(OCH 3
)-C
6
H-CH=C(CH
3 B.840 2,-(CH 3 3 6H-CH=C (CH 3 B.840 2-OCH 2
CH
3
-C
6
H
4 -CH=C (CH 3 30B.842 3-OCH 2
CH
3
-C
6
H
4 -CH=C (CH 3 B. 842 4-O(CH 2
CH
3
-C
6
H
4 -CH=C (CH 3 B. 843 3-0O(CH 2 2
CH
3
C
6
H
4 -CH=C (CH 3 35B.845 3-O(CH 2 2
CH
3
-C
6
H
4
-CH=C(CH
3 35B.846 4-O(CH 2
)CH
3
-C
6
H
4 -CH=C (CH 3 B.847 2-OCH(CH 3 2
-C
6
H
4
-CH=C(CH
3 B.848 4-OCH(CH 3 2
-C
6
H
4
-CH=C(CH
3 40B.849 4-OCH(CH 3 2
-C
6
H
4
-CH=C(CH
3 40B.850 3-OC(CH 3 3
-C
6
H
4
-CH=C(CH
3 B. 850 4-QC(CH=C)-C 6
H
4
-CH=C(C
3 B. 851 2-OCH 2
CH=CH
2
-C
6
H
4 -CH=C (CH 3 852 4-OCH 2
CH=CH
2
-C
6
H
4 -CH=C (CH 3 B. 854 2-CF 3
-C
6
H
4 -CH=C (CH 3 B. 855 3-CF 3
-C
6
H
4 -CH=C (CH 3 'Ilk 0050/46043 227 No.
R
B.856 4-CF 3
-C
6
H
4 -CH=O (CH 3 B.857 2-002CH 3 6
H
4 -CH=C (OH 3 B.858 3-C0 2
CH
3
-C
6
H
4
-CH=C(CH
3 B.859 4-C02CH 3
-C
6
H
4 -CH=C (CH 3 B.860 2-CO2CH 2
CH
3
-C
6
H
4 -CH=C (OH 3 B. 861 3-CO 2
CH
2
CH
3
-C
6
H
4 -CH=o (OH 3 862 4-C0 2
CH
2
CH
3
-C
6
H
4 -CH=C (CH 3 B.863 2-CONH 2
-C
6
H
4 -CH=C (OH 3 B.864 3-CONH 2
-C
6
H
4 -CH=C (CH 3 B. 865 4-CONH 2
-C
6
H
4 -CH=C (CH 3 B.866 2-CON (CH 3 2
-C
6
H
4 -CH=C (CH 3 B.867 3-CON (CH 3 2
-C
6
H
4 -CH=C (CH 3 B.868 4-CON (CH 3 2
-C
6
H
4 -CH=C (CH 3 B. 869 2-CONHCH 3
-C
6
H
4 -CH=C (CH 3 B.870 3-CONHCH 3
-C
6
H
4 -CH=C (CH 3 B.871 4-CONHCH 3
-C
6
H
4 -CH=C (CH 3 B.872 2-NH 2
-C
6
H
4 -CH=O (OH 3 B.873 3-NH 2
-C
6
H
4 -CH=C (CH 3 B.874 4-NH 2
-C
6
H
4
-CH=C(CH
3 B.875 2-N (CH 3 2
-C
6
H
4 -CH=C (CH 3 B.876 3-N(CH 3 2
-C
6
H
4
-CH=C(CH
3 B.877 4-N(CH 3 2
-C
6
H
4
-CH=C(CH
3 B. 878 2-NHCH 3
-C
6
H
4 -CH=C (CH 3 B.879 3-NHCH 3
-C
6
H
4 -CH=C (OH 3 B. 880 4-NHCH 3
-C
6
H
4 -CH=C (CH 3 B.881 2-CSNH 2
-C
6
H
4 -CH=C (CH 3 B. 882 3-CSNH 2
-C
6
H
4 -CH=C (OH 3 B. 883 4-CSNH 2
-C
6
H
4 -CH=C (CH 3 B.884 2-SCH 3
-C
6
H
4
-CH=C(CH
3 B.885 3-SCH 3
-C
6
H
4 -CH=C (CH 3 B.886 4-SCH 3
-C
6
H
4
-CH=C(CH
3 B.887 2-SOCH 3
-C
6
H
4 -CH=C (OH 3 B.888 3-S00H 3
-C
6
H
4
-CH=C(CH
3 B.889 4-SQOH 3
-C
6
H
4 -CH=O (OH 3 B. 890 2-SQ 2
CH
3
-C
6
H
4 -OH=C (OH 3 B. 891 3-SO 2
OH
3
-C
6
H
4 -OH=C (OH 3 892 4-S0 2 0H 3
-C
6
H
4 -CH=O (OH 3 B.893 2-OCF 3
-C
6
H
4 -CH=C (CH 3 B.894 3-00F 3
-C
6
H
4 -OH=o (CH 3 0050/46043 228 No.
R
B. 895 4-00F 3
-C
6
H
4 -CH=C (OH 3 B. 896 2-OCHF 2
-C
6
H
4 -CH=O (OH 3 5B.897 3-OCHF 2
-C
6
H
4
-CH=C(CH
3 B. 898 4-OCHF 2
-C
6
H
4 -OH=C (OH 3 B. 899 3-OF 3 4-00F 3 6
H
3
-CH=C(CH
3 B. 900 2-CH 2
CH
2
F-C
6
H
4 -CH=O (OH 3 10B.901 3-CH 2
CH
2
F-C
6
H
4 -CH=C (CH 3 B.902 4-CH 2
CH
2
F-C
6
H
4 -OH=C (CH 3 B. 903 2-CH 2
CF
3
-C
6
H
4 -CH=C (OH 3 B.904 3-CH 2
CF
3
-C
6
H
4 -CH=C (CH 3 B.905 4-CH 2
CF
3
-C
6
H
4 -CH=C (OH 3 isB. 906 2-CF 2
CHF
2
-C
6 11 4 -CH=C (OH 3 B. 907 3-CF 2
CHF
2
-C
6
H
4 -CH=C (CH 3 B.908 4-CF 2
%O-HF
2
-C
6
H
4 -CH=C (OH 3 B.909 2-CHF 2
-C
6
H
4 -CH=o (CH 3 B.910 3-CHF 2
-C
6
H
4
-CH=C(CH
3 B. 911 4-CHF 2
-C
6
H
4 -CH=C (OH 3 B.912 naphthalen-1-yl-CH=o
(OH
3 B. 913 naphthalen-2-yl-CH=O
(OH
3 B.914 pyridin-2-yl-CH=C(CH 3 B. 915 pyridin-3-yl-CH=C
(CH
3 B. 916 pyridin-4-yl-CH=C
(OH
3 B. 917 5-CH 3 -pyridin-2-yl-CH=C
(OH
3 B.918 6-OH 3 -pyridin-2-yl-OH=O
(OH
3 B. 919 5-0H 3 -pyridin-3-yl-OH=O
(OH
3 B. 920 6-0H 3 -pyridin-3-yl-H=O
(OH
3 B .921 5-00H3-pyridin-2-yl-oH=o
(OH
3 B. 922 6-00H 3 -pyridin-2-yl-CH=o
(OH
3 B .923 5-00H 3 -pyridin-3-yl-CH=o
(OH
3 B. 924 6-00H 3 -pyridin-3-yl-CH=C(CH 3 B.925 4-O1-pyridin-2-yl-oH=o
(OH
3 B.926 5-O1-pyridin-2-yl-OH=O
(OH
3 B. 927 6-O1-pyridin-2-yl-OH=O (OH 3 B.928 2-O1-pyridin-3-yl-OH=O(CH 3 B. 929 5-O1-pyridin-3-yl-CH=O(CH 3 B. 930 6-O1-pyridin-3-yl-CH=o
(OH
3 931 2-O1-pyridin-4-yl-oH=O (OH 3 B.932 3, 5-012-pyridin-2-yl-OH=O
(OH
3 B. 933 pyrimidin-2-yl-OH=O
(OH
3 yV 0050/46043
"A~
229 B. 3R31-yrmdn2ylC= C 3 B. 935 5-C1-pyrimidin-2-yl-CH=C
(CH
3 B. 936 4-CH-pyrimidin-2-yl-CH=C(CH 3 B. 937 5-CH 3 -pyrimidin-2-yl-CH=C(CH 3 B. 938 4-CH 3 -pyrimidin-2-yl-CH=C
(CH
3 B. 939 5-OCH 3 -pyrimidin-2-yl-CH=C(CH 3 B.99 B. 941 2-pyrimidin-4-yl-CH=c
(CH
3 B. 942 6-C -pyrimidin-4-yl-CH=C
(CH
3 B.9432 2 6-C 2 -pyrimidin-4-yl-CH=C
(CH
3 B. 944 2,-C 3 -pyrimidin-4-yl-CH=C
(CH
3 B. 945 6-CH 3 -pyrimidin-4-yl-CH=C
(CH
3 B. 946 2-CH 3 -pyrimidin-4-yl-CH=C(CH 3 B. 947 6-OCH 3 -pyrimidin-4-yl-CH=C
(CH
3 B. 948 pyrimidyiiin--y-H=CCH=C( B. 949 2-pyrimidin-5-yl-CH= c (CH 3 B.949 2-CH-pyrimidin-5-yl-CH=C
(CH
3 B. 951 2-CH 3 -pyrimidin-5-yl-CH=C(CH 3 B. 952 furan--yl-CH=C(CH 3
H=CCH
B. 953 4-furan-2-yl-CH=C
(CH
3 B. 954 4-C1-furan-2-yl-CH=C
(CH
3 B.954 4-Cl-furan-2-yl-CH=C
(CH
3 B. 956 4-CH-furan-2-yl-CH=C(CH 3 B. 957 5-Br-furan-2-yl-CH=C
(CH
3 B. 958 5-C1-furan-2-yl-CH=C
(CH
3 B. 959 5-CN-furan-2-yl-CH=C
(CH
3 B. 960 5-CH-furan-2-yl-CH=C
(CH
3 B. 961 furan3-ylra-H=C CH=C() 3 B.961 5-furan-3-yl-CH=C(CH 3 B. 963 5-C1-furan-3-yl-CH=C
(CH
3 B. 964 5-CN-furan-3-yl-CH=C
(CH
3 B. 965 5-CH-furan-3-yl-CH=C
(CH
3 B. 966 th-2-u--yl-CH=C(CH 3 B. 967 4-thien-2-yl-CH=C
(CH
3 B. 968 4-C1-thien-2-yl-CH=C(CH 3 B. 969 4-Cl-thien-2-yl-CH=C
(CH
3 B. 970 4-CH-thien-2-yl-CH=C
(CH
3 B. 971 5-Br-thien-2-yl-CH=C(CH 3 B. 972 5-C1-thien-2-yl-CH=C
(CH
3 0050/46043 230 No.
R
B. 973 5-CN-thien-2-yl-CH=C (CH 3 B.974 5-CH 3 -thien-2-yl-CH=C (CH 3 B.975 thien-3-yl-CH=C(CH 3 B. 976 5-Br-thien-3-yl-CH=C(CH 3 B.977 5-C 1-thien-3-yl-CH=C (CH 3 B. 978 5-CN-thien-3-yl-CH=C(CH 3 10B.979 5-CH 3 -thien-3-yl-CH=C
(CH
3 108 xzo--lCHCC3 B.981 4-oxazol-2-ylCC) 3 B. 981 4-Br-oxazol-2-yl-CH=C (CH 3 B. 982 4-C1-oxazol-2-yl-CH=C (CH 3 983 4-CH3-oxazol-2-yl-CH=C
(CH
3 B.984 4-CH-oxazol-2-yl-CH=C (CH 3 B. 985 5-Brl-oxazol-2-yl-CH=C(CH 3 B. 986 5-Ci-oxazoi-2-yl-CH=C(CH 3 20B.987 5-CH3-oxazol-2-yl-CH=C(CH 3 B. 988 oxazol-2-yl-CH=C(CH 3 B.9890 2-oxazol-4-yl-CH=C(CH 3 B. 990 2-Br-oxazol-4-yl-CH=C (CH 3 25B.991 2-C 1-oxazol-4-yl-CH=C (CH 3 992 2-CN3-oxazol-4-yl-CH=C (CH 3 B. 993 2-C6H5-oxazol-4-yl-CH=C (CH 3 B. 994 2-C 6 H-oxazol-4-yl-CH=C (CH 3 B. 995 5-Br-oxazol-4-yl-CH=C(CH 3 30B.997 5-C1-oxazol-4-yl-CH=C
(CH
3 30B.997 5-CH3-oxazol-4-yl-CH=C(CH 3 B.999 5-CH 3 -xazl-4-yl-CH=C(C) 999 -oxazol-5-yl-CH=C(CH 3 B. 1000 4-Br-oxazol-5-yl-CH=C (CH 3 B. 1001 4-C1-oxazol-5-yl-CH=C (CH 3 B. 1002 4-CN3-oxazol-5-yl-CH=C(CH 3 B. 1003 4-CH-oxazol-5-yl-CH=C(CH 3 B. 1004 2-Cr-oxazol-5-yl-CH=C(CH 3 1005 2-CN-oxazol-5-yl-CH=C(CH 3 B. 1006 2-CN3-oxazol-5-yl-CH=C(CH 3 B.1008 2-Hoxazo--l--yl-CHCH 3 B. 1008 4-isoxazol-3-yl-CH=C(CH3 B.1010 4-Cr-isoxazol-3-yl-CH=C(CH 3 B.1011 4-CN-isoxazol-3-yl-CH=C (CH 3 0050/ 46043 231 No.
R
B. 10 12 4-CH 3 -isoxazol-3-yl-CH=C(CH 3 B. 1013 5-Br-isoxazol-3-yl-CH=C(CH 3 B. 1014 5-C1-isoxazol-3-yl-CH=C(CH 3 B. 1015 5-CN-isoxazol-3-yl-CH=C(CH 3 B. 1016 5-CH 3 -isoxazol-3-yl-CH=C(CH 3 B. 1017 isoxazol-4-yl-CH=C(CH 3 1018 3-Br-isoxazol-4-yl-CH=C(CH3 1009 3C-ioao--y-HCC3 B. 1019 3-C1-iSoxazol-4-yl-CH=C(CH 3 B. 1020 3-CN3-isoxazol-4-yl-CH=C(CH 3 B. 1021 3-CH-isoxazol-4-yl-CH=C(CH 3 is B. 1022 5-Br-isoxazol-4-yl-CH=C(CH 3 1023 5-C1-isoxazol-4-yl-CH=C(CH 3 B. 1024 5-CN3-isoxazol-4-yl-CH=C(CH 3 B. 1025 35-CH 3 isoxaz o-yl CcH=C() 3 B.1027 is5-(CH3)-isoxaol-4-l-CHC(CH 3 20B.1028 3-isoxazol-5-yl-CH=C(CH 3 B. 1028 3-Br-isoxazol-5-yl-CH=C(CH 3 B. 1029 3-CN-isoxazol-5-yl-CH=C(CH 3 B. 1030 3-CH3-isoxazol-5-yl-CH=C(CH 3 1031 3-C6H5-isoxazol-5-yl-CH=C(CH 3 B. 1032 3-C 6
H
5 -isoxazol-5-yl-CH= C(cH 3 B. 1033 4-Cl, 3-C6H 5 -isoxazol-5-yl-CH=C(CH 3 B. 1034 4-Br,-H-isoxazol-5-yl-Hc(CH 3 B. 1035 4-Br-isoxazol-5-yl-CH=C(CH 3 1036 4-Cl-isoxazol-5-yl-CH=C(CH 3 B. 1037 4-CH3-isoxazol-5-yl-CH=C(CH 3 B. 1038 4-hioxazl-5-ylCH=C(H 3 1039 4-thiazol-2-yl-CH=C(CH 3 1040 4-Br-thiazol-2-yl-CH=C(CH 3 B. 1041 4-Cl-thiazol-2-yl-CH=C(CH 3 B. 1042 4-CN3-thiazol-2-yl-CH=C(CH 3 1043 4-CH-thiazol-2-yl-CH=C(CH 3 1044 5-Br-thiazol-2-yl-CH=C(CH 3 B. 1045 5-Cl-thiazol-2-yl-CH=C(CH 3 B. 1046 5-CH3-thiazol-2-yl-CH=C(CH 3 1047 5-hiao-hiazl-2-yl-CH3c(H 3 B. 1048 2-thiazol-4-yl-CH=C(CH 3 B. 1050 2-Cl-thiazol-4-yl-CH=C(CH 3 AlT 0050/46043 232 No. R 3 B. 1051 2-CN-thiazol-4-yl-CH=C
(CH
3 B. 1052 2-CH 3 -thiazol-4-yl-CH=C
(CU
3 B. 1053 5-Br-thiazol-4-yl-CH=C(CH 3 B. 1054 5-C1-thiazol-4-yl-CH=C
(CU
3 B. 1055 5-CN-thiazol-4-yl-CH=C(CH 3 B. 1056 5-CH 3 -thiazol-4-yl-CH=C(CH 3 B. 1057 thiazol-5-yl-CH=C(CH 3 B. 1058 4-Br-thiazol-5-yl-CH=C
(CH
3 B. 1059 4-C1-thiazol-5-yl-CH=C(CH 3 B. 1060 4-CN-thiazol-5-yl-CH=C(CH 3 B. 1061 4-CH 3 -thiazol-5-yl-CH=C
(CU
3 B. 1062 2-Br-thiazol-5-yl-CH=C
(CU
3 B. 1063 2-C1-thiazol-5-yl-CH=C(CH 3 B1064 2-CN-thiazoi-5-yi-CH=C(CH 3 B. 1065 2-CH 3 -thiazol-5-yl-CH=C
(CU
3 B. 1066 isothiazol-3-yl-CH=C
(CU
3 B. 1067 4-Br-isothiazol-3-yl-CHi=C(CH 3 B. 1068 4-C1-isothiazol-3-yl-CU=C
(CU
3 B. 1069 4-CN-isothiazol-3-yl-CU=C
(CU
3 B. 1070 4-CU 3 -isothiazol-3-yl-CU=C
(CU
3 B. 1071 5-Br-isothiazol-3-yl-CU=C
(CU
3 B. 1072 5-C1-isothiazol-3-yl-CU=C
(CU
3 B. 1073 5-CN-isothiazo.-3-yl-CU=C
(CU
3 B. 1074 5-CU 3 -isothiazol-3-yl-CU=C
(CU
3 B. 1075 isothiazol-4-yl-CU=C(CH 3 B. 1076 3-Br-isothiazol-4-yl-CH=C(CH 3 B. 1077 3-Cl-isothiazol-4-yl-CU=C(CU 3 B. 1078 3-CN-isothiazol--4-yl-CH=C(CH 3 B. 1079 3-CU 3 -isothiazol-4-yl-CU=C
(CU
3 B. 1080 5-Br-isothiazol-4-yl-CU=C(CH 3 B. 1081 5-Cl-isothiazol-4-yl-CH=C(CH 3 B. 1082 5-CN-isothiazol-4-yl-CH=C(CH 3 B. 1083 5-CH 3 -isothiazol-4-yl-CH=C(CU 3 B.1084 3,5-(CH3) 2 -isothiazol-4-yl-CH=C(CH 3 B. 1085 isothiazol-5-yl-CH=C(CH 3 B. 1086 3-Br-isothiazol-5-yl-CH=C(CH 3 B. 1087 3-Cl-isothiazol-5-yl-CH=C(CH 3 B. 1088 3-CN-isothiazol-5-yl-CH=C(CH 3 B.-1089 3-CH 3 -isothiazol-5-yl-CH=C(CH 3 0050/46043 233 No. R 3 B. 1090 4 -Br-isothiazol-5-yl-CU=C(CU 3 B. 1091 4 -Cl-isothiazo1--5-yl-CH=C(CH 3 B.1092 4 -CN-isothiazol-5-yl-cC=(CH 3 B. 1093 4 -C H3-isothiazol-5-yl-C=C
(CU
3 B. 1094 imidazol-2-yl-CH=C(CU 3 B. 1095 l-Cl-imidazol-2-yl-CH=C(CH 3 B. 1096 l-Br-imidazol-2-yl-C=C (CU 3 B. 1097 1-CN-imidazol-2-yl-CH=C(CH 3 B. 1098 l-CH3-imidazol-2-yl-CU=C(CH 3 B. 1099 4 -Cl-imidazol-2-yl-CH=C(CU 3 B. 1100 4 -Br-imidazol-2-yl-C=C
(CU
3 B. 1101 4 -CN-imidazol-2-yl-CH=C(CH 3 B. 1102 4 -CH3-imidazol-2-yl-CH=C(CU 3 1.1103l 1-CU 3 5S rCl~imiLdazoiL-2-yl-CH=C(CU 3 B. 1104 1 4 -(CH3)2-iMidazol-2-yl-CH=C(CU 3 B.1105 1,5- (CH3) 2-imidazol-2-yl-C=C
(CH
3 B. 1106 imidazol-4-yl-CU=C(CU 3 B. 1107 2 -Cl-imidazol-4-yl-CH=C(CU 3 B. 1108 2 -Br-imidazol-4-yl-CH=C(C 3 B. 1109 2 -CN-imidazol-4-yl-CH=C(CH 3 B. 1110 l-CH3-imidazol-4-yl-CH=C(CU 3 B. 1111 2 -CH3-imidazol-4-yl-CH=C(CU 3 B. 1112 5-Cl-imidazol-4-yl-CH=C(CH 3 B. 1113 5-Br-imidazol-4-yl-C=C
(CU
3 B. 1114 5-CN-imidazol-4-yl-CH=C(CU 3 B. 1115 5-CU3-imidazol-4-yl-CU=C(CH 3 B. 1116 1-CU 3 -Cl-imidazol-4-yl-CH=C(CH 3 B.1117 1 2 (CH3)2-imidazol-4-yl.CH=C(CU 3 B.1118 l,5-(CH3)2-imidazol-4-yl-CH=C(CH 3 B. 1119 pyrazol-3-yl-CU=C
(CU
3 B. 1120 5-Br-pyrazal-3-yl-CU=C(CH 3 B. 1121 5-Cl-pyrazol-3-yl-CH=C(CU 3 B. 1122 5-CN-pyrazol-3-yl-C=C
(CU
3 B. 1123 5-CU3-pyrazol-3-yl-CH±C(
CU
3 B. 1124 1-C6H5-pyrazol-3-yl-CH=C(CU 3 B. 1125 4 -Br--pyrazol-3-yl-CU=C(CU 3 B. 1126 4 -Cl-pyrazol-3-yl-CU=C(CH 3 B. 1127 4 -CN-pyrazol-3-yl-CU=C(CH 3 4~;;TA~x.B.1128 4 -U-pyrazol-3-yl-CU=C(CU 3 0050/46043 234 No.
R
B. 1129 1-CH3-pyrazol-3-yl-CH=C(CH 3 B.1130 1,4-(CH3)2-pyrazol-3-yl-CH=C(CH 3 B.1131 1, 5- (CHA)2-pyrazol-3-yl-CH=C (CH 3 B. 1132 1-OH 3 4-C1-pyrazol-3-yl-CH=C(CH 3 B. 1133 1-OH 3 5-C1-pyrazol-3-yl-CH=C(CH 3 B. 1134 pyrazol-4-yl-CH=O(CH 3 B. 1135 3-Br-pyrazol-4-yl-CH=o (OH 3 1 01 63 C y a o l 4 y H C C 3 B. 1136 3-CN-pyrazol-4-yl-CH=C(CH 3 B. 1137 3-CH3-pyrazol-4-yl-H=C(H 3 B. 1139 1-CH 3 -pyrazol-4-yl-CH=C(CH 3 B.1140 1,5-(CH3) 2 -pyrazol-4-yl-CH=C(CH 3 B.1141 1, 3- (CHA)2-pyrazol-4-yl-CH=C
(CH
3 BD. 11"L42 1-O 3 3i-pyrazol-4-yi-CH=C(CH 3 B. 1143 1-H, 5-O1-pyrazol-4-yl-OH=o
(OH
3 B.1144 pyrazol-5-yl-CH=C(CH 3 B. 1145 3-Br-pyrazol-5-yl-H=(Ci 3 B. 1146 3-C1-pyrazol-5-yl-CH=O(0H 3 B. 1147 3-CN-pyrazol-5-yl-OH=O(0H 3 B. 1148 3-CH 3 -pyrazol-5-yl-CH=O(0H 3 B. 1149 1-CH 3 -pyrazol-5-yl-CH=C(0H 3 B. 1150 4-Br-pyrazol-5-yl-OH=O(OH 3 B. 1151 4-O1-pyrazol-5-yl-OH=C(CH 3 B. 1152 4-ON-pyrazol-5-yl-OH=O(OH 3 B. 1153 4-0H 3 -pyrazol-5-yl-CH=C(CH 3 B.1154 1,3-(CH3) 2 -pyrazol-5-yl-CH=O(CH 3 B.1155 1, 4- (CH 3 2 -pyrazol-5-yl-CH=C(CH 3 B. 1156 1-OH 3 3-O1-pyrazol-5-yl-OH=O(OH 3 B.1157 1-OH 3 4-O1-pyrazol-5-yl-OH=O(OH 3 B.1158 1,3,4-oxadiazol-5-yl-CH=C(CH 3 B. 1159 2-0H 3 3,4-oxadiazol-5-yl-OH=C(OH 3 B. 1160 2-0F 3 3,4-oxadiazol-5-yl-OH=C(CH 3 B. 1161 2-00H 3 3, 4-oxadiazol-5-yl-OH=O(CH 3 B.1162 2 -Ol-l,3,4-oxadiazol-5-yl-CH=C(CH 3 B. 1163 2 -CH(CH3)2-1,3,4-oxadiazol-5-yl-OH=C(CH 3 B.1164 1,3,4-oxadiazol-2-yl-OH=C(CH 3 B. 1165 5 -CH3-1,3,4-oxadiazol-2-yl-CH=C(CH 3 451 65 C 3 1, x d a o -2 y H C C 3 B. 1166 5-OC 3 3,4-oxadiazol-2-yl-H=(H 3 0050/46043 is V/ 235 No.
R
B.1168 5-C1-1,3,4-oxadiazol-2-yl-CH=C(CH 3 B.1169 5-CH (CH 3 2 3,4-oxadiazol-2-yl-CH=C
(CH
3 B. 1170 5-C 6
H
5 3, 4-oxadiazol-2-yl-CH=C(CH 3 B.1171 1,2,4-oxadiazol-3-yl-CH=C(CH 3 B. 1172 5-CH 3 4-oxadiazol-3-yl-CH=C(CH 3 B. 1173 5-CF 3 -1,2,4-oxadiazol-3-yl-CH=C(CH 3 B.1174 5-C1-1,2,4-oxadiazol-3-yl-CH=C(CH 3 B. 1175 5-CH(CH 3 2 -1,2,4-oxadiazol-3-yl-CH=C
(CH
3 B. 1176 1,2,4-triazol-3-yl-CH=C(CH 3 B.1177 1-CH3-1,2,4-triazol-3-yl-CH=C(CH 3 B.1178 5-CH3-1,2,4-triazol-3-yl-CH=C(CH 3 B.1179 5-CF3-1,2,4-triazol-3-yl-CH=C(CH 3 B. 1180 5-OCH 3 2, 4-triazol-3-yl-CH=C(CH 3 B.1181 5D-CiL-iL,2,4-triazol-3-yi-CH=C(CH 3 B. 1182 5-CH(CH 3 2 -1,2,4-triazol-3-yl-CH=C(CH 3 B. 1183 1-C 6
H
5 2, 4-triazol-3-yl-CH=C
(CH
3 B. 1184 1,3,4-thiadiazol-5-yl-CH=C(CH 3 B. 1185 2-CH 3 3, 4-thiadiazol-5-yl-CH=C
(CH
3 B.1186 2-CF 3 -1,3,4-thiadiazol-5-yl-CH=C(CH 3 B.1187 2-OCH 3 -1,3,4-thiadiazol-5-yl-CH=C(CH 3 B. 1188 2-Cl-1,3,4-thiadiazol-5-yl-CH=C(CH 3 B.1189 2-CH(CH 3 2 -1,3,4-thiadiazol-5-yl-CH=C(CH 3 B.1190 1,3,4-thiadiazol-2-yl-CH=C(CH 3 B. 1191 5-CH 3 4-thiadiazol-2-yl-CH=C(CH 3 B. 1192 5-CF 3 -1,3,4-thiadiazol-2-yl-CH=C(CH 3 B. 1193 5-OCH 3 3,4-thiadiazol-2-yl-CH=C(CH 3 B. 1194 5-C1-1,3, 4-thiadiazol-2-yl-CH=C(CH 3 B.1195 5-CH(CH 3 2 -1,3,4-thiadiazol-2-yl-CH=C(CH 3 B. 1196 5-C 6
H
5 -1,3,4-thiadiazol-2-yl-CH=C(CH 3 B.1197 1,2,4-thiadiazol-3-yl-CH=C(CH 3 B. 1198 5-CH 3 4-thiadiazol-3-yl-CH=C(CH 3 B. 1199 5-CF 3 -1,2,4-thiadiazol-3-yl-CH=C(CH 3 B. 1200 5-OCH 3 4-thiadiazol-3-yl-CH=C(CH 3 B.1201 5-C1-1,2,4-thiadiazol-3-yl-CH=C(CH 3 B.1202 5-CH(CH 3 2 -1,2,4-thiadiazol-3-yl-CH=C(CH 3 B. 1203 pyrrol-2-yl-CH=C(CH 3 B. 1204 4-Cl-pyrrol-2-yl-CH=C(CH 3 B. 1205 4-Br-pyrrol-2-yl-CH=C(CH 3 B. 1206 4-CH 3 -pyrrol-2-yl-CH=C(CH 3 0050/ 46043 236 No.
R
B. 1207 4-C6H5-pyrrol-2-yl-CH=C(CH 3 B. 1208 benzimidazol-2-yl-CH=C(CH 3 B.1209 quinolin-2-yl-CH=C(CH 3 B.1210 C=-CH B.1211 CH 2 C CH B.1212
CH
2 C CC1 B.1213 CH 2 C CBr B.1214
CH
2
C=CI
B.1215
CH
2
C=-CCH
3 B.1216
CH
2 C CCH 2
CH
3 B.1217 CH 2 C CCH 2 0H B.1218
CH
2 C CCH 2
NH
2 B.1219
CH
2 C CCH 2 Cl B.1220
CH
2
CCCH
2 OCHn 3 B. 1221
CH
2 C CCH 2
OCH
2
CH
3 B.1222 CH 2
C=-CCH
2
SCH
3 B.1223
CH
2 C MCCH 2 N (CH 3 2 B.1224
CH
2 C =CC 6
H
B.1225 CH 2
CH
2
C-C
B.1226 CH 2
CH
2 C =CC1 B.1227 CH 2
CH
2 C =-CBr B.1228 CH 2 CH!;C CI B.1229
CH
2
CH
2 C =-CCH 3 B. 1230
CH
2
CH
2 C =CCH 2
CH
3 B.1231
CH
2
CH
2 C =-CCH 2 0H B. 1232
CH
2 CH7C CCH 2
NH
2 B.1233
CH
2
CH
2 C CCH 2 Cl B. 1234
CH
2
CH
2 C CCH 2
OCH
3 B.1235
CH
2
CH
2
C-=CCH
2
OCH
2
CH
3 B.1236
CH
2
CH
2
C=CCH
2
SCH
3 B.1237
CH
2
CH
2 C CCH 2 qN(CH 3 2 B.1238 CH 2
CH
2 C =CC 6
H
B.1239 CH 2
CH
2
CH
2 C CH B.1240
CH
2
CH
2
CH
2 C Cc B.1241 CH 2
CH
2
CH
2 C CBr B.1242
CH
2
CH
2
CH
2 C ci B. 1243 CH 2
CH
2
CH
2 C CCH 3 4 52 4C 2 H C H C C 2 H B. 1244 CH 2
CH
2
CH
2 C CCH 2 0H 3 B.145 C 2
H
2
HCCHO
0050/46043 237 No. R B. 1246
CH
2
CH
2
CH
2
C=-CCH
2
NH
2 B. 1247 CH2CH 2
CH
2 C =CCH 2 Cl B. 1248 CH2CH 2
CH
2 C -CCH 2 0CH 3 B. 1249 CH2CH 2
CH
2 C -CCH 2
OCH
2
CH
3 B. 1250 CH2CH 2
CH
2
CEECCH
2
SCH
3 B.1251 CH2CH 2
CH
2 C CCH 2 N (CH 3 2 B. 1252
CH
2
CH
2
CH
2 C CC 6
H
B.1253 CH(CH )-C B.1254
CH(CH
3 )C=CC1 B.1255 CH (CH 3 C CBr B.1256 CH (CH 3 C CI B.1257 CH (CH 3
CCCH
3 B.1258 CH (CH 3 C CCH 2
CH
3 B. 1259
CH(CH
3 1)tCCCH 2 u B.1260
CH(CH
3 )C -CCU 2
NH
2 B.1261
CH(CH
3 )C CCH 2 C1 B.1262
CH(CH
3 )C CCH 2 0CH 3 B.1263 CH (CH 3 C CCH 2
OCH
2
CH
3 B.1264 CH (CH 3 C CCH 2
SCH
3 B.1265 CH (CH 3 C aCCH 2 N (CH 3 2 B.1266
CH(CH
3
)C=CC
6
H
B.1267
CH=CH-C
6
H
B.1268
C(CH
3
)=CH-C
6
H
B.1269 C =CC 6
H
I
A
N-VIO
0050/46043 238 No. R 3 B. 1270 1,3-(CH3) 2 -pyrazol-5-yl-CH 2 B.1271 1,4-(CH 3 )2-pyrazol-5-yl-CH 2 B. 1272 1-CH 3 3-Cl-pyrazol-5-yl-CH 2 B. 1273 1-CH 3 4-Cl-pyrazol-5-yl-CH 2 B. 1274 1,3, 4-oxadiazol-5-yl-CH 2 B. 1275 2 -CH3-1,3,4-oxadiazol-5-yl-CH 2 B. 1276 2 -CF3--1,3,4-oxadiazol-5-yl-CH 2 B. 1277 2 -OCH3-i,3,4-oxadiazol-5-yl-CH 2 B. 1278 2 -Cl-1,3,4-oxadiazol-5-yl-CH 2 is B.1279 2 -CH(CH3)2-1,3,4-oxadiazol-5-yl-CH 2 B. 1280 1,3, 4-oxadiazol-2-yl-CH 2 B. 1281 5-CH 3 3,4-oxadiazol-2-yl-CH 2 B. 1282 5-CF 3 3, 4-oxadiazol-2-yl-CH 2 B. 1283 5-OCH3-1,3,4-oxadiazol-2-yl-CH 2 B. 1284 5-cl-i, 3, 4-oxadiazol-2-yl-CH 2 B.1285 5-CH(CH3)2-1,3,4-oxadiazol-2-yl-CH 2 B. 1286 5-C6H5-l, 3, 4-oxadiazol-2-yl-CH 2 B. 1287 1,2, 4-oxadiazol-3-yl-CH 2 B. 1288 5-CH 3 2, 4-oxadiazol--3-yl-CH 2 B. 1289 5-CF 3 2, 4-oxadiazol-3-yl-CH 2 B. 1290 5-OCH3-1,2,4-oxadiazol-3-yl-CH 2 B. 1291 5-Cl-1,2,4-oxadiazol-3-yl-CH 2 B.1292 5-CH (CH3) 2 2, 4-oxadiazol-3-yl-CH 2 B. 1293 1,2, 4-triazol-3-yl-CH 2 B. 1294 1-CH 3 2, 4-triazol-3-yl-CH 2 B.1295 5-CH 3 2, 4-triazol-3-yl-CH 2 B. 1296 5-CF 3 -1 4-triazol-3-yl-CH 2 B.1297 5-OCH 3 -1 4-triazol-3-yl-CHi 2 B. 1298 5-Cl-i, 2, 47triazol-3-yl-CH.
2 B.1299 5-CH(CH3) 2 -1,2,4-triazol-3-yl-CH 2 B. 1300 1-C 6
H
5 2, 4-triazol-3-yl-CH 2 B. 1301 1,3,4-thiadiazol-5-yl-CH 2 B. 1302 2 -CH3-1,3,4-thiadiazol-5-yl-CH 2 B. 1303 2-CF 3 3,4-thiadiazol-5-yl-CH 2 B. 1304 2-OCH 3 3,4-thiadiazol-5-yl-0H 2 B. 1305 2-CH 2
OCH
3 3,4-thiadiazol-5-yl-CH 2 B. 1306 2-Cl-i, 3,4-thiadiazol-5-yl-CH 2 B. 1307 2-CH (CH 3 2-1, 3, 4-thiadiazol-5-yl-CH 2 0050/46043 239 No.
R
B. 1308 1,3, 4-thiadiazol-2-yl-CH 2 B.1309 5-CH 3 3, 4-thiadiazol-2-yl-CH 2 B. 1310 5-CF3-1,3,4-thiadiazol-2-yl-CH 2 B. 1311 5-OCH 3 3, 4-thiadiazol-2-yl-CH 2 B. 1312 5-C1-1,3,4-thiadiazol-2-yl-CH 2 B.1313 5-CH(CH3)2-1,3,4-thiadiazol-2-yl-CH 2 B. 1314 5-C6H5-1,3,4-thiadiazol-2-yl-CH 2 B.35104tiaizl3y-H B. 13156,2 -tHiad2,-ial-3-l-3H 2
CH
B. 1316 5-CH3-1,2,4-thiadiazol-3-yl-CH 2 B. 1317 5-OC3-1,2,4-thiadiazol-3-yl-CH 2 B. 1318 5-CH-1,2,4-thiadiazol-3-yl-CH 2 B. 1319 5-CH()-1,2,4-thiadiazol-3-yl-
CH
2 B. 13201 5CH(CH32-1,2,4-thidao-3y- B. 1321 pyrrl=prr2-yl-CH 2 B. 1322 4-C 1-pyrrol-2-yl-CH 2 B.1324 4-Br3-pyrrol-2-yl-CH 2 B. 1324 4-C6H-pyrrol-2-yl-C 2 B. 1326 benz imidazol-2-yl-CH 2 B. 1327 quinolin-2-yl-CH 2 B. 1328 oxiranyl-CH 2 B. 1329 2-CH 3 -oxiran-2-yl-CH 2 B. 1330 2-CH 3 -oxiran-3-yl-CH 2 B. 1331 2,2- (OH 3 2-oxiran-3-y1-CH 2 B. 1332 2,3-(CH 3 2 -oxiran-3-yl-CH 2 B.1333 2,3,3-(CH 3 3 -oxiran-2-yl-CH 2 B.1334 oxiranyl-CH(0H 3 B. 1335 2-CH 3 -oxiran-2-yl-CH(CH 3 B. 1336 2-CH 3 -oxiran-3-yl-CH(CH 3 B.1337 2,2-(CH3)2-oxiran-3-yl-OH(CH 3 B.1338 2, 3- (CH3) 2-oxiran-3-yl-CH
(CH
3 B.1339 2 ,3,3-(CH3) 3 -oxiran-2-yl-CH(CH 3 B. 1340 1, -Cl2-CYClopropan-2-yl-CH 2 B. 1341 2-CH 3 1, -Cl2-cyclopropan-2-yl-CH 2 B. 1342 2-OH 3 1, -C12-CYClopropan-3-yl-CH 2 B.1343 2,2-(CH 3 2 1, 1-Cl2-cyclopropan-3-yl-CH 2 B.1344 2,3-(CH 3 2 l,1-C12-CYClopropan-3-yl-CH 2 B.1345 2,3,3-(0H 3 3 1, 1-C12-CYClopropan-2-yl-CH 2 B.-1346 1,1l-Cl2-CYClopropan-2-yl-CH(CH 3 0050/46043 240 No. R 3 B. 1347 2-CH 3 1,1-Cl2-CYClopropan-2-yl-CH(CH 3 B.1348 2-CH 3 1,1-Cl2-CYClopropan-3-yl-CH(CH 3 B.1349 2,2-(CH 3 2 l,l-Cl2-CYClopropan-3-yl-CH(CH 3 B.1350 2,3-(CH 3 2 1, l-C12-CYClopropan-3-yl-CH(CH 3 B.1351 2,3,3-(CH 3 3 l,1-C12-CYClopropan-2-yl-CH(CH 3 B. 1352 1, 1-Br2-cyclopropan-2-yl-CH 2 B. 1353 2-CH 3 1, 1-Br2-CYClopropan-2-yl-CH 2 103 42 C 3 r -c c o r p n 3 y H B. 1354 2,-CH 3 1, 1-Br2- Clopropan-3-yl-CH 2 B.1356 2,2-(CH 3 2 1,1-Br 2 -cyclopropan-3-yl-CH 2 B.1357 2,3,-(CH 3 1, -Br 2 -CYClopropan--yl-CH 2 B.1358 3 3 1,1-Br2-cyclopropan-2-yl-CH(C3 2 B. 1359 2-CH 3 1, 1-Br2-CYClopropan-2-yl-CH(CH 3 B. 1360 2-CH 3 1, i-Br2-CYClopropan-3-yi-CH(CH 3 B.1361 2,2-(CH 3 2 1,1-Br 2 -cyclopropan-3-yl-CH(CH 3 B.1362 2,3-(CH 3 2 1, 1-Br 2 -CYClopropan-3-yl-CH(CH 3 B. 1363 2,3,3-(CH 3 3 1, 1-Br2-cyclopropan-2-yl-CH(CH 3 B.1364 CH(CH 3 )-O-phenyl B. 1365 CH(CH 3
)CH
2 -O-pheny.
B.1366 CH 2
CH(CH
3 )-O-phenyl B.1367 CH(CH 3
)CH(CH
3 )-O-phenyl B.1368 CH (CH 3
(CH
2 2 -O-phenyl B. 1369 CH 2 CH (CH 3
)CH
2 -O-phenyl B.1370 (CH2) 2 0H(CH 3 )-O-phenyl B.1371 CH(CH 3
)CH(CH
3
)CH
2 -O-phenyl B.1372 CH(CH 3
)CH
2
CH(CH
3 )-O-phenyl B.1373 CH 2
CH(CH
3
)CH(CH
3 )-O-phenyl B.1374 CH(CH 3
)CH(CH
3
)CH(CH
3 )-O-phenyl B.1375 CH(CH 3
)(CH
2 3 -O-pheny.
B. 1376 2-F-C 6
H
4
-OCH
2 B. 1377 3-F-C 6
H
4
-OCH
2 B. 1378 4-F-C 6
H
4
-OCH
2 B.1379 2,3-F 2
-C
6
H
3
-OCH
2 B. 1380 2, 4-F 2
-C
6
H
3 -C1 2 B. 1381 2, 5-F 2
-C
6
H
3
-OCH
2 B. 1382 2, 6-F 2
-C
6
H
3 -0CH 2 B. 1383 3,4-F 2
-C
6
H
3 -0CH 2 B. 1384 3, 5-F 2
-C
6
H
3
-OCH
2 B. 1385 2-Cl-C 6
H
4
-OCH
2 0050/46043 241 No. R 3 B. 1386 3-Cl-C 6 Ii 4
-OCH
2 B. 1387 4-Cl-C 6
H
4
-OCH
2 B.1388 2,3-C1 2
-C
6
H
3
-OCH
2 B. 1389 2,4-Cl 2
-C
6
H
3
-OCH
2 B.1390 2, 5-Cl 2
-C
6
H
3
-OCH
2 B. 1391 2, 6-C1 2
-C
6
H
3
-OCH
2 B.1392 3, 4-C1 2
-C
6
H
3
-OCH
2 B. 1393 3,5-C1 2
-C
6
H
3 -0CH 2 B.1394 2,3, 4-C1 3
-C
6
H
2
-OCI
2 B. 1395 2,3, 5-Cl 3
-C
6
H
2
-OCH
2 B. 1396 2,3, 6-C1 3
-C
6
H
2
-OCH
2 B.1397 2,4,5-Cl 3
-C
6
H
2
-OCH
2 B. 1398 2,4, 6-Cl 3
-C
6
H
2
-OCH
2 B. 1399 3,4, 5-C1 3
-C
6
H
2
-OCH
2 B. 1400 2-Br-C 6
H
4
-OCH
2 B.1401 3-Br-C 6
H
4
-OCH
2 B. 1402 4-Br-C 6
H
4
-OCH
2 B. 1403 2, 3-Br 2
-C
6
H
3
-O-CH
2 B. 1404 2, 4-Br 2
-C
6
H
3
-O-CH
2 B.1405 2,5-Br 2
-C
6
H
3
-O-CH
2 B. 1406 2, 6-Br 2
-C
6
H
3
-O-CH
2 B. 1407 3, 4-Br 2
-C
6
H
3
-O-CH
2 B. 1408 3,5-Br 2
-C
6
H
3
-O-CH
2 B.1409 2-F, 3-Cl-C 6
H
3
-O-CH
2 B.1410 2-F, 4-Cl-C 6
H
3
-O-CH
2 B.1411 2-F, 5-C1-C 6
H
3
-O-CH
2 B.1412 2-F, 3-Br-C 6
H
3
-O-CH
2 B.1413 2-F, 4-Br-C 6
H
3
-O-CH
2 B.1414 2-F, 5-Br-C 6
H
3
-O-CH
2 B.1415 2-Cl, 3-F-C 6
H
3
-O-CH
2 B.1416 2-Cl, 4-F-C 6
H
3
-O-CH
2 B.1417 2-Cl, 5-F-C 6
H
3
-Q-CH
2 B.1418 2-Cl, 3-Br-C 6
H
3
-O-CH
2 B.1419 2-Cl, 4-Br-C 6
H
3
-O-CH
2 B.1420 2-Cl, 5-Br-C 6
H
3
-O-CH
2 B.1421 2-Br, 3-F-C 6
H
3
-O-CH
2 B.1422 2-Br, 4-F-C 6
H
3
-O-CH
2 B.1423 2-Br, 5-F-C 6
H
3
-O-CH
2 B.1424 2-Br, 3-Cl-C 6
H
3
-O-CH
2 0050/46043 242 No.
R
B.1425 2-Br, 4-Cl-C 6
H
3
-O-CH
2 B.1426 2-Br, 5-Cl-C 6
H
3
-O-CH
2 B.1427 4-Cl, 3,5-Br 2
-C
6
H
2
-O-CH
2 B. 1428 2-CN-C 6
H
4
-O-CH
2 B. 1429 3-CN-C 6
H
4
-O-CH
2 B. 1430 4-CN-C 6
H
4
-O-CH
2 B. 1431 2-N0 2
-C
6
H
4
-O-CH
2 B.42 3N2CH--H B. 1432 3-N0 2
-C
6
H
4
-O-CH
2 B. 1433 4-N0 2
-C
6
H
4
-O-CH
2 B. 1434 2-CH 3
-C
6
H
4
-O-CH
2 B. 1435 3-CH 3
-C
6
H
4
-Q-CH
2 B.1437 2,C 3 H2C 6 H -CH 2 B. J438 2,4-(CH 3 2
-C
6
H
3
-O-CH
2 B.1439 2,5-(CH 3 2
-C
6
H
3
-Q-CH
2 B.1440 2,5-(CH 3 2
-C
6
H
3 -0-CH 2 B.1441 3, 4-(CH 3 2
-C
6
H
3
CH
2 B.1442 3,4-(CH 3 2
-C
6
H
3
-O-CH
2 B.1443 2,-(HCH 3
)-C
6
H--CH
2 B. 1443 2-CH 2
CH
3
-C
6
H
4
-O-CH
2 B. 1444 4-CH 2
CH
3
-C
6
H
4
-O-CH
2 B. 1445 4-CH (CH 3
-C
6
H
4
CH
2 B. 1446 2-CH (CH 3 2
-C
6
H
4
-O-CH
2 B. 1447 4-CH (CH 3 2
-C
6
H
4
-Q-CH
2 B.1449 3-C(CH 3 3
-C
6
H
4
-O-CH
2 B. 1450 4-C (CH 3 3
-C
6
H
4 -0-CH 2 B. 1451 2-C 6
H
5
-C
6
H
4
-O-CH
2 B. 1452 3-C 6
H
5
-C
6
H
4
-O-CH
2 B.1453 4-C 6
H
5
-C
6
H
4
-O-CH
2 B. 1454 2-0CH 3
-C
6
H
4
-O-CH
2 B. 1455 3-OCH 3
-C
6
H
4
-O-CH
2 B. 1456 4-0CH 3
-C
6
H
4 -0-CH 2 B.1457 2,3-(OCH 3 2
-C
6
H
3
-O-CH
2 B.1458 2,4-(OCH 3 2
-C
6
H
3 -0-CH 2 B.1459 2, 5- (OCH 3 2
-C
6
H
3 -0-CH 2 B.1460 2,6-(OCH 3 2
-C
6
H
3 -0-CH 2 B.1461 3, 4- (OCH 3 2
-C
6
H
3 -0-CH 2 B.1462 3, 5- (OCH 3 2
-C
6
H
3 -0-CH 2 B.1463 13, 4, 5-(OCH 3 3
-C
6
H
2
-O-CH
2 v- 0050/46043 243 No.
R
B. 1464 2-OCH 2
CH
3
-C
6
H
4
-O-CH
2 B. 1465 3-OCH 2
CH
3
-C
6
H
4
-O-CH
2 B. 1466 4-OCH 2
CH
3
-C
6
H
4
-O-CH
2 B. 1467 2-O(CH 2 2
CH
3
-C
6
H
4
-OCH
2 B.1468 3-0 (CH 2 2
CH
3
-C
6
H
4
-OCH
2 B. 1469 4-O(CH 2 2
CH
3
-C
6
H
4
-OCH
2 B. 1470 2-OCH (CH 3 2
-C
6
H
4
-OCH
2 1 04 13 O H H 3 6 4 O H B. 1471 4-OCH (CH 3 2
-C
6
H
4
-OCH
2 B. 1472 3-OC(CH 3 )3-C 6
H
4
-OCH
2 B. 1473 3-OC(CH 3 3
-C
6
H
4
-OCH
2 B. 1474 4-OC(2CH=C)-C 6
H
4
-CH
2 B.1476 2-OCH 2
CH=CH
2
-C
6
H
4
-OCH
2 B. 1477 4-OCH 2
CH=CH
2
-C
6
H
4
-OCH
2 B. 1478 2-CF 3
-C
6
H
4
-OCH
2 B.1479 3-CF 3
-C
6
H
4 -0CHi 2 B. 1480 4-CF 3
-C
6
H
4
-OCH
2 B. 1481 2-CO 2
CH
3
-C
6
H
4
-OCH
2 B. 1482 3-CO 2
CH
3
-C
6
H
4
-OCH
2 B.1483 4-CO 2
CH
3
-C
6
H
4
-OCH
2 B. 1484 2-CO 2
CH
2
CH
3
-C
6
H
4 -0CH 2 B. 1485 3-CO 2
CH
2
CH
3
-C
6
H
4
-OCH
2 B. 1486 4-CO 2
CH
2
CH
3
-C
6
H
4
-OCH
2 B. 1487 2-CONH 2
-C
6
H
4
-OCH
2 B.1488 3-CONH 2
-C
6
H
4 -0CH 2 B. 1489 4-CONH 2
-C
6
H
4
-OCH
2 B. 1490 2-CON (CH 3 2
-C
6
H
4
-OCH
2 B. 1491 3-CON (CH 3 2
-C
6
H
4
-OCH
2 B.1492 4 -CON (CH 3 2
-C
6
H
4
-OCH
2 B. 1493 2-CONHCH 3
-C
6
H
4 -0CH 2 B. 1494 3-CONHCH 3
-C
6
H
4
-OCH
2 B. 1495 4-CONHCH 3
-C
6
H
4
-OCH
2 B.1496 2-NH 2
-C
6
H
4
-OCH
2 B.1497 3-NH 2
-C
6
H
4
-OCH
2 B.1498 4-NH 2
-C
6
H
4
-OCH
2 B.1499 2-N (CH 3 2
-C
6
H
4
-OCH
2 B.1500 3-N(CH 3 2
-C
6
H
4
-OCH
2 B.1501 4-N(CH 3 2
-C
6
H
4 -0CH 2 B.1502 2-NHCH 3
-C
6
H
4
-OCH
2 St 0050/46043 244 No. R B. 1503 3-NHCH 3
-C
6
H
4
-OCH
2 B. 1504 4-NHCH 3
-C
6
H
4
-OCH
2 B.1505 2-CSNqH 2
-C
6
H
4
-OCH
2 B. 1506 3-CSNH 2
-C
6
H
4
-OCH
2 B. 1507 4-CSNH 2
-C
6
H
4
-OCH
2 B. 1508 2-SCH 3
-C
6
H
4
-OCH
2 B. 1509 3-SCH 3
-C
6
H
4
-OCH
2 1 05 04 C 3 C 6 4 O H B. 1510 4-SCH 3
-C
6
H
4
-CH
2 B. 1511 3-SOCH 3
-C
6
H
4
-OCH
2 B. 1512 3-SOCH 3
-C
6
H
4
-OCH
2 B. 1513 4-SOCH 3
-C
6
H
4
-OCH
2 B. 1515 3-SO2CH 3
-C
6
H
4
-OCH
2 B. 15 16 4-SO2CH 3
-C
6
H
4
-OCH
2 B. 1517 2-OCF 3
-C
6
H
4
-OCH
2 B.1518 3-OCF 3
-C
6
H
4
-OCH
2 B. 1519 4-OCF 3
-C
6
H
4 -0CH 2 B. 1520 2-OCHF 2
-C
6
H
4
-QCH
2 B. 1521 3-OCHF 2
-C
6
H
4
-OCH
2 B.1522 4-OCHF 2
-C
6
H
4
-OCH
2 B.1523 3-CF 3 4-OCF 3
-C
6
H
3
-OCH
2 B. 1524 2-CH 2
CH
2
F-C
6
H
4 -0CH 2 B. 1525 3-CH 2
CH
2
F-C
6
H
4
-OCH
2 B. 1526 4-CH 2
CH
2
F-C
6
H
4
-OCH
2 3057 2-HC3C64OH B. 1527 2-CH 2
CF
3
-C
6
H
4
-OCH
2 B. 1528 4-CH2CF 3
-C
6
H
4
-OCH
2 B. 1529 2-CH 2
CF-C
6
H
4
-OCH
2 B. 1530 2-CF 2
CHF
2
-C
6
H
4
-QCH
2 B.1532 3-CF 2
CHF
2
-C
6
H
4
-OCH
2 B. 1532 4-CCHF 2
-C
6
H
4
OCH
2 B. 1533 2-CHF 2
-C
6
H
4
-OCH
2 B. 1535 4-CHF 2
-C
6
H
4
-OCH
2 B. 1536 naphthalen-1-Yl-OCH 2 B. 1537 naphthalen-2-Yl-0CH 2 B. 1538 pyridin-2-Yl-OCH 2 B. 1539 pyridin-3-yl-0CH 2 B. 1540 pyridin-4-yl-0CH 2 B.1541 5-CH3-pyridin-2-yl-OCH 2 0050/46043 ____245 No. R B. 1542 6-CH 3 -pyridirl-2-yl-OCH 2 B. 1543 5-CH 3 -pyridiri-3-Yl-OCH 2 B.1544 6-CH 3 -pyridin-3-Yl-OCH 2 B. 1545 5-OCH 3 -pyridin-2-yl-OCH 2 B. 1546 6-OCH 3 -pyridin-2-yl-OCH 2 B. 1547 5-OCH 3 -pyridin-3-yl-OCH 2 B. 1548 6-OCH 3 -pyridin-3-yl-OCH 2 105 94 Cl p r d n l O H B. 1549 5-C1-pyridin-2-yl-OCH 2 B. 1550 5-Cl-pyridin-2-yl-OCH 2 B. 1551 2-Cl-pyridin-2-yl-OCH 2 B. 1552 5-Cl-pyridin-3-yl-OCH 2 B. 1553 5-Cl-pyridin-3-yl-OCH 2 B. 1554 -C B. 155 2~C1pyri J -4-y'-OCH 2 B. 1556 3,5-C12-pyridin-2-yl-OCH 2 B.1557 pyrimidin-2-yl-OCH 2 B. 1558 4-Cl-pyrimidin-2-yl-OCH 2 B. 1559 5-Cl-pyrimidin-2-yl-OCH 2 B. 1560 4-CH3-pyrimidin-2-yl-OCH 2 B. 1561 5-CH3-pyrimidin-2-yl-OCH 2 B. 1562 4-OCH3-pyrimidin-2-yl-OCH 2 B. 1563 5-OCH 3 -pyrimidin-2-yl-OCH 2 B. 1564 pyrimidin-4-yl-OCH 2 B. 1565 2-Cl-pyrimidin-4-yl-OCH 2 B. 1566 6-Cl-pyrimidin-4-yl-OCH 2 B. 1567 2, 6-C12-pyrimidin-4-yl-OCH 2 B. 1568 2-CH 3 -pyrimidin-4-yl-OCH 2 B. 1569 6-CH 3 -pyrimidin-4-y1-OCH 2 B. 1570 2-OCH3-pyrimidin-4-yl-OCH 2 B. 1571 6-OCH 3 -pyrimidin-4-yl-Cpi 2 B. 1572 pyrimidin-5-yl-OCH 2 B. 1573 2-C1-pyrimidin-5-yl-OCH 2 B. 1574 2-CH3-pyrimidin-5-yl-OCH 2 B. 1575 2 -OCH3-pyrimidin-5-yl-OCH 2 B. 1576 furan-2-yl-OCH 2 B. 1577 4-Br--furan-2-yl-OCH 2 B. 1578 4-C1-furan--2-yl-OCH 2 B. 1579 4-CN-furan-2-Yl-0CH 2 B.1580 4-C 3 -uan-2-yl-OCH 2 0050/46043 246 No. R 3 B. 1581 5-Br-furan-2-yl-OCH 2 B. 1582 5-Cl-furan-2-yl-0CH 2 B.1583 5-CN-furan-2-yl-OCH 2 B. 1584 5-CH 3 -furan-2-yl-OCH 2 B. 1585 furan-3-yl-OCH 2 B. 1586 5-Br-furan-3-yl-OCH 2 .0 B.1587 5-Cl-furan-3-yl-OCH 2 B. 1588 5-CN-furan-3-y-OCH 2 B. 1589 5-CH 3 -furan-3-yl-CH 2 B. 1590 thien-2-yl-OCH 2 B. 1591 4-Br-thien-2-yl-OCH 2 B.1592 4-Cl-thien-2-yl-OCH 2 B. 1593 4-CN-thien-2-yl-CH 2 B. 1594 4-CH 3 -thien-2-Yl-0H4 2 B. 1595 5-Br-thien-2-yl-OCH 2 0 B.1596 5-Cl-thien-2-yl-OCH 2 B. 1597 5-CN-thien-2-yl-OCH 2 B. 1598 5-CH 3 -thien-2-Yl-OCH 2 B. 1599 thien-3-yl-OCH 2 s B. 1600 5-Br-thien-3-yl-OCH 2 B. 1601 5-Cl-thien-3-yl-OCH 2 B. 1602 5-CN-thien-3-yl-CH 2 B. 1603 5-CH 3 -thien-3-yl-OCH 2 B. 1604 oxazol-2-yl-OCH 2 B.1605 4-Br-oxazol-2-yl-OCH 2 B. 1606 4-C1-oxazol-2-yl-OCH 2 B. 1607 4-CN-oxazol-2-yl-OCH 2 B. 1608 4-CH 3 -oxazol-2-y.-0CH 2 B.1609 5-Br-oxazol-2-yl-CH 2 B. 1610 5-Cl-oxazol-2-yl-OCH 2 B. 1611 5-CN-oxazol-2-yl-OCH 2 B. 1612 5-CH3-oxazol-2-y-CH 2 B.1613 oxazol-4-yl-OCH 2 B. 1614 2-Br-oxazol-4-yl-OCH 2 B. 1615 2 -C1-oxazol-4-yl-ocH 2 B. 1616 2-CN--oxazol-4--yl-OCH 2 B. 1617 2-CH3-oxazol-4-yl-OCH 2 B. 1618 2-C6H 5 -oxazol-4-yl-OCH 2 B.1619 5-Br-oxazol-4-yl-OCH 2 0050/46043 247 No.
R
B. 1620 5-Cl-oxazol-4-yl-OCH 2 B. 1621 5-CN--oxazol-4-yl-OCH 2 B. 1622 5-CH 3 -oxazol-4-yl-OCH 2 B. 1623 oxazol-5-yl-OCH 2 B. 1624 4-Br-oxazol-5-yl-OCH 2 B. 1625 4-C1-oxazol-5-yl-OCH 2 B. 1626 4-CN-oxazol-5-yl-OCH 2 B. 1627 4-CH 3 -oxazol-5-yl-OCH 2 B. 1628 2-Br-oxazol-5-yl-OCH 2 B. 1629 2-Cl--oxazol-5-yl-OCH 2 B. 1630 2-CN-oxazol-5-yl-OCH 2 B. 1631 2-CH 3 -oxazol-5-yl-OCH 2 B. 1632 isoxazol-3-yl-OCH 2 B3.1633 4-Br-isoxazol-3-yi-CH 2 B. 1634 4-Cl-isoxazol-3-yl-OCH 2 B. 1635 4-CN-isoxazol-3-yl-OCH 2 B. 1636 4-Cf 3 -isoxazol-3-yl-OCH 2 B. 1637 5-Br-isoxazol-3-yl-OCH 2 B. 1638 5-C1-isoxazol-3-yl-OCH 2 B. 1639 5-CN-isoxazol-3-yl-OCH 2 B. 1640 5-CH 3 -iSoxazol-3-yl-OCH 2 B. 1641 isoxazol-4-yl-OCH 2 B. 1642 3-Br-isoxazol-4-yl-OCH 2 B. 1643 3-Cl-isoxazol-4-yl-OCH 2 B. 1644 3-CN-isoxazol-4-yl-QCH 2 B. 1645 3-CH 3 -isoxazol-4-yl-QCH 2 B. 1646 5-Br-isoxazol-4-yl-OCH 2 B. 1647 5-C1-isoxazol-4-yl-OCH 2 B. 1648 5-CN~-isoxazo1-4-yl-OCH 2 B. 1649 5-CH 3 -isoxazol-4-yl-OCH 2 B. 1650 3,5-(CH 3 2 -isoxazol-4-yl-OCH 2 B. 1651 isoxazol-5-yl-OCH 2 B. 1652 3-Br-isoxazol-5-yl-OCH 2 B. 1653 3-Cl-isoxazol-5-yl-OCH 2 B. 1654 3-CN-isoxazol-5-yl-OCH 2 B. 1655 3-CH 3 -isoxazol-5-yl-OCH 2 B. 1656 3-C 6
H
5 -isoxazol--5-yl-QCH 2 B. 1657 4-Cl, 3-C 6
H
5 -isoxazol-5-yl-OCH 2 B. 1658 4-Br, 3-C 6 HS-isoxazol-5-yl-OCH 2
I
0050/46043 248 No.
R
3 B. 1659 4-Br-isoxazol-5-yl-QCH 2 B. 1660 4-Cl-isoxazol-5-yl-OCH 2 B.1661 4-CN-isoxazol-5-yl-OCH2 B. 1662 4-CH 3 -isoxazol-5-yl-OCH 2 B. 1663 thiazol-2-yl-OCH 2 B. 1664 4-Br-thiazol-2-yl-OCH 2 B. 1665 4-Cl-thiazol-2-yl-OCH2 1066 4CNtizl--lOH B. 1666 4-CH3-thiazol-2-yl-OCH 2 B. 1667 5-CH-thiazol-2-Yl-OCH 2 B. 1668 5-Cr-thiazol-2-yl-OCH 2 B. 1669 5-CN-thiazol-2-yl-OCH 2 15B.1671 5-CN3-thiazol-2-yl-OCH 2 B. 1671 thiazol- 2-yl-OCH 2 B. 1672 thiaz-h-yl-OCH 2
OCH
B. 1673 2-Cr-thiazol-4-yl-OCH 2 20B.1675 2-CN-thiazol-4-yl-OCH 2 B. 1675 2-CN3-thiazol-4-yl-OCH 2 B. 1676 2-CH-thiazol-4-Yl-OCH 2 B. 1677 5-Cr-thiazol-4-yl-OCH2 25B.1679 5-CN-thiazol-4-yl-OCH 2 B. 1679 5-CN3-thiazol-4-yl-OCH 2 B. 1680 5-hiao-hiazl-4-ylOCH B. 1681 thiaz-h-yl-OCH 2
OCH
B. 1682 4-Cr-thiazol-5-yl-OCH 2 30B.1684 4-CN-thiazol-5-yl-QCH 2 B. 1684 4-CN3-thiazol-5-yl-OCH 2 B. 1685 4-CH-thiazol-5-yl-OCH 2 B. 1686 2-Cr-thiazol-5-yl-OCH 2 35B.1688 2-CN-thiazol-5-yl-OCH 2 B. 1688 2-CN3-thiazol-5-yl-OCH 2 B. 1690 2-Cthiazol--yl-CH 2 B. 1690 4-isothiazol-3-yl-OCH 2 1691 4-Cr-isothiazol-3-yl-OCH 2 B. 1692 4-C1-isothiazol-3-yl-OCH 2 B. 1693 4-CN3-isothiazol-3-yl-OCH 2 B. 1694 4-CH 3 -isothiazol-3-yl-OCH2 B. 1695 5-Br-isothiazol-3-yl-OCH 2 B.1697 5-CN-isothiazol-3-yl-OCH 2 0050/46043 249 No. R 3 B. 1698 5-CH 3 -isothiazol-3-yl-OCH 2 B. 1699 isothiazol-4-yl-OCH 2 B. 1700 3-Br-isothiazol-4-yl-OCH 2 B. 1701 3-Cl-isothiazol-4-yl-0CH 2 B. 1702 3-CN-isothiazol-4-yl-0CH 2 B. 1703 3-CH 3 -isothiazol-4-yl-OCH 2 B. 1704 5-Br-isothiazol-4-yl-CH 2 B 7510- s th a o l O H B. 1705 5-C1-isothiazol-4-yl-OCH 2 B. 1706 5-CH3-isothiazol-4-yl-CH 2 B. 1707 35-CH 3 -isothiazol-4-yl-OCH 2 B.1709 istiao-isylOthaol4ylO B.1710 3-isothiazol-5-yl-OCH 2 171 B. 1711 3-C1-isothiazo-5-yl-OCH~ 2 B. 1712 3-CN-isothiazol-5-yl-OCH 2 B. 1713 3-CH 3 -isothiazol-5-yl-OCH 2 B. 1714 4-Br-isothiazol-5-yl-OCH 2 B. 1715 4-Cl-isothiazol-5-yl-OCH 2 B. 1716 4-CN-isothiazol-5-yl-OCH 2 B.-1717 4-CH 3 -isothiazol-5-yl-OCH 2 B. 1718 imidazol-2-yl-OCH 2 B. 1719 1-Cl-imidazol-2-yl-OCH 2 B. 1720 1-Br-imidazol-2-yl-OCH 2 B. 1721 1-CN-imidazol-2-yl-OCH 2 B. 1722 1-CH 3 -imidazol-2-yl-OCH 2 B. 1723 4-Cl-imidazol-2-yl-OCH 2 B. 1724 4-Br-imidazol-2-yl-0CH 2 B. 1725 4-CN-imidazol-2-yl-OCH 2 B. 1726 4-CH 3 -imidazol-2-yl-OCH 2 B. 1727 1-CH 3 5-C1-imidazol-2-yl-CH 2 B. 1728 1,4-(CH 3 2 -imidazol-2-yl-0CH 2 B.1729 1, 5- (CH 3 2 -imidazol-2-yl-OCH 2 B.1730 imidazol-4--yl-OCH 2 B. 1731 2-C1-imidazol-4-yl-OCH 2 B. 1732 2-Br-imidazol-4-yl-C1 2 B. 1733 2-CN--imidazol-4-yl-OCH 2 B. 1734 1-CH 3 -imidazol-4-yl-0CH 2 4 57 52 C H m d z l l O H B. 1735 2-CH-imidazol-4-yl-OCH 2 B.13A",-mdzl--lOH Ql 0050/46043 250 No. R 3 B. 1737 5-Br-imidazol-4-yl-OCH 2 B. 1738 5-CN-imidazol-4-yl-OCH 2 B.1739 5-CH 3 -imidazol-4-yl-OCH 2 B. 1740 1-CH 3 5-Cl-imidazol-4-yl-00H 2 B. 1741 1,2-(CH3)2-imidazol-4-yl-OCH 2 B. 1742 1,5-(CH3)2-imidazol-4-yl-OCH 2 B. 1743 pyrazol-3-yl-OCH 2 B 741 0r p r z l l O H B. 1744 5-Cr-pyrazol-3-yl-OCH 2 B. 1745 5-CN-pyrazol-3-Yl-0CH 2 B. 1746 5-CN3-pyrazol-3-yl-OCH 2 B. 1748 1-C6H5-pyrazol-3-yl-OCH 2 B. 1749 4-Br-pyrazol-3-yl-OCH 2 B. 175 0 4-Ci-pyrazoi-3-yl-OCH 2 B. 1751 4-CN-pyrazol-3-yl-OCH 2 B.1752 4-CH 3 -pyrazolL-3-yl-OCH 2 B. 1753 1-CH3-pyrazol-3-yl-OCH 2 B.1754 1,4- (CH 3 )2-pyrazol-3-yl-OCH 2 B.1755 1,5- (OH 3 2-pyrazol-3-y1-OCH 2 B.1756 1-CH 3 4-C1-pyrazol-3-yl-OCH 2 B. 1757 1-H, 5-C1-pyrazol-3-yl-00H 2 B. 1758 pyrazol-4-yl-OCH 2 B. 1759 3-Br-pyrazol-4-yl-OCH 2 B. 1760 3-Cl-pyrazol-4-yl-OCH 2 B.71 3C-yao4ylOH B. 1761 3-CH3-pyrazol-4-yl-OCH 2 B. 1762 I-CH 3 -pyrazol-4-yl-OCH 2 B. 1763 1,-CH 3 )ra--y l-00H 2
OCH
B. 1764 1,5-(CH3)2-pyrazol-4-yl-OCH 2 B. 1766 1-OH 3 3-Cl-pyrazol-4-yl-OCH 2 B. 1767 1-OH 3 5-C 1-pyrazol-4-yl-00H 2 B. 1768 pyrazol-5-yl-OCH 2 B.1769 3-Br-pyrazol-5-yl-OCH 2 B. 1770 3-Cl-pyrazol-5-yl-00H 2 B. 1771 3-CN-pyrazol-5-yl-OCH 2 B. 1772 3-CH 3 -pyrazol-5-yl-OCH 2 B. 1773 1-CH3-pyrazol-5-yl-OCH 2 4 57 44 B r p r z l l O H B. 1774 4-Cr-pyrazol-5-yl-OCH 2 0050/46043 251 No. R 3 B. 1776 4-CN-pyrazol-5-yl-OCH 2 B. 1777 4-CH 3 -pyrazol-5-yl-OCH 2 B. 1778 1,3-(CH 3 )2-pyrazol-5-yl-0CH 2 B.1779 1, 4- (CH3) 2-pyrazol-5-yl-OCH 2 B. 1780 1-CH 3 3-C1-pyrazol-5-yl-OCH 2 B. 1781 1-CH 3 4-Cl-pyrazol-5-yl-OCH 2 B. 1782 1,3,4-oxadiazol-5-yl-OCH 2 107 32 C 3 1 3 4 ox d a o l O H B. 1783 2-CH 3 -1,3,4-oxadiazo1-5-yl-OCH 2 B. 1784 2-C 3 3,4-oxadiazol-5-yl-OCH 2 B. 1785 2-CH-1, 3, 4-oxadiazol-5-yl-OCH 2 B. 1786 2-CH()-1,3,4-oxadiazol-5-yl-
OCH
2 B. 1788 1,3, 4-oxadiazol-2-yl-OCH 2 5-CH 3 34-oxadiazol-2-yl-0CH 2 B. 1790 5-CF3-1,3,4-oxadiazol-2-yl-OCH 2 B. 1791 5-Cl-i, 3, 4-oxadiazol-2-yl-OCH 2 B. 1792 5-CH (CH3) 2-1, 3, 4-oxadiazol-2-yl-OCH 2 B. 1793 5-C 6
H
5 3, 4-oxadiazol-2-yl-OCH 2 B. 1794 1,2, 4-oxadiazol-3-yl-OCH 2 B. 1795 5-CH 3 2,4-oxadiazol-3-yl-OCH 2 B. 1796 5-CF3-1,2,4-oxadiazol-3-yl-0CH 2 B. 1797 5-Cl-l,2,4-oxadiazol-3-yl-OCH 2 B.1798 5-CH (CH3) 2 2, 4-oxadiazol-3-yl-OCH 2 B. 1799 1,2, 4-triazol-3-yl-0CH 2 B. 1800 l-CH3-1,2,4--triazol-3-yl-OCH 2 B. 1801 5-CH3-1,2,4-triazol-3-yl-OCH 2 B. 1802 5-CF3-1,2,4-triazol-3-yl-OCH 2 B.1803 5-QCH 3 2, 4-triazol-3-yl-OCH 2 B.1804 5-Cl-1,2,4-triazol-3-yl-OCH 2 B.1805 5-CH (CH3) 2-1, 2, 4-triazol-3-yl-OCH 2 B. 1806 l-C6H5-1, 2, 4-triazol-3-yl-OCH 2 B. 1807 1,3, 4-thiadiazol-5-yl-OCH 2 B. 1808 2-CH 3 4-thiadiazol-5-yl-OCH 2 B. 1809 2-CF 3 3, 4-thiadiazol-5-yl-0CH 2 B. 1810 2-OCH 3 3,4-thiadiazol--5-yl-OCH 2 B. 1811 2-Cl-i, 3, 4-thiadiazol-5-yl-OCH 2 B.1812 2 -CH(CH3) 2 -1,3,4-thiadiazol-5-yl-C1 2 458 31 3 4 h a i z l l O H B.1814 1,C3 34-thiadiazol-2-yl-
OCH
2 B.11XH-,3 -tidao--lo~ 1 1 0050/46043 is 252 No.
R
B. 1815 5-CF 3 3, 4-thiadiazol-2-yl-OCH 2 B. 1816 5-OCH 3 3,4-thiadiazol-2-yl-00H 2 B. 1817 5-C1-1,3,4-thiadiazol-2-yl-OCH 2 B.1818 5-CH(CH3) 2 -1,3,4-thiadiazol-2-yl-OCH 2 B. 1819 5-C 6
H
5 3, 4-thiadiazol-2-yl-OCH 2 B. 1820 1,2,4-thiadiazol-3-yl-OCH 2 B. 1821 5-CH 3 -1,2,4-thiadiazol-3-yl-OCH 2 B. 1822 5-CF 3 -1,2,4-thiadiazol-3-yl-OCH 2 B. 1823 5-OCH 3 2, 4-thiadiazol-3-yl-OCH 2 B. 1824 5-Cl-1,2,4-thiadiazol-3-yl-OCH 2 B. 1825 5-CH(CH 3 2 -1,2 ,4-thiadiazol-3-yl-0CH 2 B. 1826 pyrrol-2-yl-OCH 2 B. 1827 4-Cl-pyrrol-2-Yl-OCH 2 b. 1828Z 4-Br-pyrrol-2-yl-OCH 2 B. 1829 4-CH 3 -pyrrol-2-yl-OCH 2 B. 1830 4-C 6
H
5 -pyrrol-2-Yl-OCH 2 B. 1831 benzimidazol-2-yl-QCH 2 B. 1832 quinolin-2-yl-OCH 2 B. 1833 1, 1-C1 2 -CYClopropan-2-yl-OCH 2 B. 1834 2-CH 3 1, 1-C12-cyclopropan-2-yl-OCH 2 B. 1835 2-OH 3 1, 1-C12-CYClopropan-3-y1-OCH 2 B.1836 2,2-(CH 3 2 1,1-Cl2-CYClopropan-3-yl-00H 2 B.1837 2,3-(CH 3 2 1,1-C12-CYClopropan-3-yl-OCH 2 B.1838 2,3,3-(CH 3 3 1, 1-C12-CYClopropan-2-yl-00H 2 B. 1839 1, 1-C12-CYClopropan-2-yl-O-CH(CH 3 B. 1840 2-CH 3 1, 1-C12-CYClopropan-2-yl-O-CH(CH 3 B. 1841 2-OH 3 1, 1-C1 2 -cyclopropan-3-yl-O-CH(CH 3 B.1842 2,2-(CH 3 2 1,1-Cl2-CYClopropan-3-yl-O-CH(CH 3 B.1843 2,3-(CH 3 2 1, 1-C12-CYClopropan-3-yl-O-CH(CH 3 B.1844 2,3,3-(CH 3 3 1, 1-C12-CYClopropan-2-yl-O-CH(CH 3 B. 1845 1, 1-Br 2 -CYClopropan-2-yl-OCH 2 B.1846 2-OH 3 1, 1-Br 2 -cyclopropan-2-Yl-OCH 2 B. 1847 2-OH 3 1, 1-Br 2 -cyclopropan-3-yl-OCH 2 B.1848 2,2-(CH 3 2 1, 1-Br2-CYClopropan-3-yl-00H 2 B.1849 2,3-(CH 3 2 1, 1-Br2-CYClopropan-3-yl-OCH 2 B.1850 2,3,3-(CH 3 3 1,1-Br2-CYClopropan-2-yl-00H 2 B. 1851 1, 1-Br 2 -cyclopropan-2-yl-OCH(CH 3 B. 1852 2-OH 3 1, 1-Br 2 -CYClopropan-2-yl-OCH(CH 3 B. 1853 2-OH 3 1, 1-Br 2 -CYClopropan-3-yl-OCH(CH 3 0050/46043 253 No.
R
B.1854 2,2-(CH 3 2 1, l-Br2-cyclopropan-3-yl-OCH(CH 3 B.1855 2,3-(CH 3 2 ll-Br2-CYClopropan-3.-yl-OCH(CH 3 B.1856 2,3,3-(CH 3 3 1, l-Br2-cyclopropan-2-yl-OCH(CH 3 B.1857 2-F-C 6
H
4
-CH(CH
3 B.1858 3-F-C 6
H
4
-CH(CH
3 B.1859 4-F-C 6
H
4
-CH(CH
3 10B.1860 2,3-F 2
-C
6
H
3
-CH(CH
3 1 08 12 4 F C H H C 3 B.1862 2,4-F 2
-C
6
H
3
-CH(CH
3 B. 1862 2,5-F2-C 6
H
3
-CH(CH
3 B.1864 2, 6-F 2
-C
6
H
3 -CH (OH 3 B.1865 3,4-F 2
-C
6
H
3
-CH(CH
3 B.1866 3,-F 2
C
6
H-CH(H
3 B. 1866 2-C1-C 6
H
4
-CH(CH
3 B. 1868 4-Cl-C 6
H
4
-CH(CH
3 B. 1868 4,-C-C 6
H-CH(CH
3 20B.1870 2,4-Cl 2
-C
6
H
3
-CH(CH
3 B.1871 2,4-C1 2
-C
6
H
3 -C H(CH 3 B.1872 2,6-Cl 2
-C
6
H
3 -CH(C1 3 B.1873 2,6-Cl 2
-C
6
H
3
-CH(CH
3 25B.1874 3,4-C1 2
-C
6
H
3
-CH(CH
3 B.1875 23,-Cl-C 6
H-CH(CH
3 B.1876 2,3,5-Cl 3
-C
6
H
2
-CH(CH
3 B.1877 2,3,5-C1 3
-C
6
H
2
-CH(CH
3 B.1878 2,4,5-CIl 3
-C
6
H
2
-CH(CH
3 B.1879 2, 4, 6-Cl 3
-C
6
H
2 -CH (CH 3 B.1880 3,4,5-Cl 3
-C
6
H
2
-CH(CH
3 B. 1881 2-Br-C 6
H
4
-CH(CH
3 B.1882 3-Br-C 6
H
4
-CH(CH
3 B. 1883 4-Br-C 6
H
4
-CH(CH
3 B.1884 2,3-Br 2
-C
6
H
3
-CH(CH
3 B.1885 2,4-Br 2
-C
6
H
3
-CH(CH
3 B.1886 2,5-Br 2
-C
6
H
3
-CH(CH
3 B.1887 2,6-Br 2
-C
6
H
3
-CH(CH
3 B.1888 3,4-Br 2
-C
6
H
3
-CH(CH
3 B.1889 3,5-Br 2
-C
6
H
3
-CH(CH
3 45B.1890 2-F, 3-C-C 6
H
3
-CH(CH
3 4 58 12 F 4 C 6 H H C 3 114B.1892 2-F, 4-C-C 6
H
3
-CH(CH
3 0050/46043 254 No. R B.1893 2-F, 3-Br-C 6
H
3
-CH(CH
3 B.1894 2-F, 4-Br-C 6
H
3
-CH(CH
3 B.1895 2-F, 5-Br-C 6
H
3
-CH(CH
3 B.1896 2-Cl, 3-F-C 6
H
3
-CH(CH
3 B.1897 2-Cl, 4-F-C 6
H
3
-CH(CH
3 B.1898 2-Cl, 5-F-C 6
H
3
-CH(CH
3 B.1899 2-Cl, 3-Br-C 6
H
3
-CH(CH
3 1 09 02 C 4 B r C H H C 3 B.1901 2-Cl, 4-Br-C 6
H
3
-CH(CH
3 B.1902 2-Cl, 5-B-C 6
H
3
-CH(CH
3 B.1903 2-Br, 4-F-C 6
H
3
-CH(CH
3 is B.1904 2-Br, 4-F-C 6
H
3
-CH(CH
3 B.1905 2-Br, 5-F-C 6
H
3
-CH(CH
3 B.1906 2-Br, 4-C'l-C 6
H
3 -CH (CH 3 B.1907 2-Br, 4-Ci-C 6
H
3
-CH(CH
3 B.1908 4-Cl, 3,5-Br 2
-C
6
H
2
-CH(CH
3 B.1909 2-CN-C 6
H
4
-CH(CH
3 B.1910 3-CN-C 6
H
4
-CH(CH
3 B.1911 4-CN-C 6
H
4
-CH(CH
3 B.1912 2-N0 2
-C
6
H
4
-CH(CH
3 B. 1913 3-N0 2
-C
6
H
4
-CH(CH
3 B.1914 4-N0 2
-C
6
H
4
-CH(CH
3 B.1915 2-CH 3
-C
6
H
4
-CH(CH
3 B. 1916 3-CH 3
-C
6
H
4
-CH(CH
3 B.1917 4-CH 3
-C
6
H
4
-CH(CH
3 B.1918 2,3-(CH 3 2
-C
6
H
3
-CH(CH
3 B.1919 2, 4- (CH 3 2
-C
6
H
3 -CH (CH 3 B.1920 2, 5- (CH3) 2
-C
6
H
3 -CH (CH 3 B.1921 2,6-(CH 3 2
-C
6
H
3
-CH(CH
3 B.1922 3,4-(CH 3 2
-C
6
H
3
-CH(CH
3 B.1923 3,5-(CH 3 2 0 6
H
3
-CH(CH
3 B.1924 2-CH (CH 3
CH
3
-C
6
H
4 -CH (CH 3 B. 1925 3-CH(CH 3
)CH
3
-C
6
H
4
-CH(CH
3 B. 1926 4-OH (OH 3
)CH
3
-C
6
H
4 -CH (OH 3 B.1927 2-CH(CH 3 2
-C
6
H
4
-CH(CH
3 B.1928 3-CH (CH 3 2
-C
6
H
4 -CH (CH 3 B. 1929 4-CH(CH 3 2
-C
6
H
4
-CH(CH
3 B.1930 3-C (CH 3 3
-C
6
H
4 -CH (CH 3 B.1931 4-C (CH 3 3
-C
6
H
4 -CH (CH 3 0I 0050/46043 255 No. R 3 B.1932 2-C 6
HS-C
6
H
4 -CH (CH 3 B. 1933 3-C 6
H
5
-C
6
H
4
-CH(CH
3 B.1934 4-C 6
H
5
-C
6
H
4
-CH(CH
3 B. 1935 2-OCH 3
-C
6
H
4
-CH(CH
3 B. 1936 3-OCH 3
-C
6
H
4
-CH(CH
3 B. 1937 4-OCH 3
-C
6
H
4
-CH(CH
3 B.1938 2,3-(OCH3)2-C 6
H
3
-CH(CH
3 1 09 92 O H 2 C 6 3 C C 3 B.1940 2,5-(0CH 3 2
-C
6
H
3
-CH(CH
3 B.1941 2,6- (OCH3) 2
-C
6
H
3 -CH (CH 3 B.1942 2,6-(OCH3) 2
-C
6
H
3
-CH(CH
3 is B.1943 3,5- (OCH3) 2
-C
6
H
3 -CH (CH 3 15B.1944 3,45- (OCH3)-C 6 H-CH (CH 3 .1944- 3 45(C)- 6
H-CH(CH
3 a94 2=OCH(CH 3
)CH
3
-C
6
H
4
-HC)
B.1946 3-OCH (CH 3
CH
3
-C
6
H
4 -CH (CH 3 B.1947 4-OCH (CH 3
CH
3
-C
6
H
4 -CH (CH 3 B.1948 2-O(CH(CH 3 )2CH 3
-C
6
H
4
-CH(CH
3 B.1949 3-O(CH(CH 3 )2CH 3
-C
6
H
4
-CH(CH
3 B.1950 4-0O(CH (CH 3 2CH 3
-C
6
H
4 -CH (CH 3 B.1951 2-OCH(CH 3 2
-C
6
H
4
-CH(CH
3 B. 1952 3-OCH (CH 3 2
-C
6
H
4 -CH (CH 3 B.1953 4-OCH(CH 3 2
-C
6
H
4
-CH(CH
3 B.1954 3-OC (CH 3 3
-C
6
H
4 -CH (CH 3 B.1955 4-OC (CH 3 3
-C
6
H
4 -CH (CH 3 B.1956 2-OCH (CH 3 CH=CH (CH 3
-C
6
H
4 -CH (CH 3 B.1957 3-OCH(CH 3
)CH=CH(CH
3
)-C
6
H
4
-CH(CH
3 B.1958 4-OCH (CH3) CH=CH (CH 3
-C
6
H
4 -CH (CH 3 B. 1959 2-CF 3
-C
6
H
4
-CH(CH
3 B.1960 3-CF 3
-C
6
H
4
-CH(CH
3 B.1961 4-CF 3
-C
6
H
4
-CH(CH
3 B. 1962 2-CO 2
CH
3
-C
6
H
4
-CH(CH
3 B. 1963 3-CO 2
CH
3
-C
6
H
4 -CH (CH 3 B.1964 4-CO2CH 3
-C
6
H
4
-CH(CH
3 B. 1965 2-CO2CH 2
CH
3
-C
6
H
4 -CH (CH 3 B. 1966 3-CO2CH2CH 3
-C
6
H
4
-CH(CH
3 B. 1967 4-CO2CH 2
CH
3
-C
6
H
4 -CH (CH 3 B. 1968 2-CONH 2
-C
6
H
4
-CH(CH
3 459 93 CO H 6 4 H C 3 H4B.1970 4-CONH 2
-C
6
H
4
-CH(CH
3
-ON
2
C
6
NCHC
3 0050/ 46043 256 No. R 3 B.1971 2-CON'(H 3 2
-C
6
H
4
-CH(CH
3 B.1972 3-CON(CH 3 2
-C
6
H
4
-CH(CH
3 B.1973 4-CON(CH 3 2
-C
6
H
4
-CH(CH
3 B. 1974 2-CONHCH 3
-C
6
H
4
-CH(CH
3 B. 1975 3-CONHCH 3
-C
6
H
4
-CH(CH
3 B. 1976 4-CONHCH 3
-C
6
H
4
-CH(CH
3 B. 1977 2-NH 2
-C
6
H
4
-CH(CH
3 B. 1978 3-NH 2
-C
6
H
4
-CH(CH
3 B. 1979 4-NH 2
-C
6
H
4
-CH(CH
3 B.1980 2-N (CH 3 2
-C
6
H
4
-CH(CH
3 B.1981 3-N (CH 3 2
-C
6
H
4 -CH (CH 3 B.1982 4-N(CH 3 2
-C
6
H
4
-CH(CH
3 B. 1983 2-NHCH 3
-C
6
H
4
-CH(CH
3 B l 184 3-NHCH 3
-C
6
H
4
-CH(CH
3 B. 1985 4-NHCH 3
-C
6
H
4
-CH(CH
3 B.1986 2-CSNH 2
-C
6
H
4
-CH(CH
3 B. 1987 3-CSNH 2
-C
6
H
4
-CH(CH
3 B. 1988 4-CSNH 2
-C
6
H
4
-CH(CH
3 B. 1989 2-SCH 3
-C
6
H
4
-CH(CH
3 B.1990 3-SCH 3
-C
6
H
4
-CH(CH
3 B. 1991 4-SCH 3
-C
6
H
4
-CH(CH
3 B. 1992 2-SOCH 3
-C
6
H
4
-CH(CH
3 B.1993 3-SOCH 3
-C
6
H
4 -CH (CH 3 B. 1994 4-SOCH 3
-C
6
H
4
-CH(CH
3 B.1995 2-SQ 2
CH
3
-C
6
H
4 -CH (CH 3 B. 1996 3-SO 2
CH
3
-C
6
H
4
-CH(CH
3 B. 1997 4-SO 2
CH
3
-C
6
H
4
-CH(CH
3 B. 1998 2-QCF 3
-C
6
H
4
-CH(CH
3 B.1999 3-OCF 3
-C
6
H
4
-CH(CH
3 B.2 000 4-OCF 3
-C
6
H
4 -CH (CH 3 B.2001 2-OCHF 2
-C
6
H
4
-CH(CH
3 B.2 002 3-OCHF 2
-C
6
H
4 -CH (CH 3 B.2003 4-OCHF 2
-C
6
H
4
-CH(CH
3 B.2004 3-CF 3 4-OCF 3
-C
6
H
3
-CH(CH
3 B.2005 2-CH 2
CH
2
F-C
6
H
4
-CH(CH
3 B.2006 3-CH 2
CH
2
F--C
6
H
4
-CH(CH
3 B.2007 4-CH 2
CH
2
F-C
6
H
4
-CH(CH
3 B .2008 2-CH 2
CF
3
-C
6
H
4 -CH (CH 3 B. 2009 13-CH 2
CF
3 -C H-CH (CH 3 0050/46043 257 No.
R
B.2010 4-CH 2
CF
3
-C
6
H
4
-CH(CH
3 B.2011 2-CF 2
CHF
2
-C
6
H
4
-CH(CH
3 B.2012 3-CF 2
CHF
2
-C
6
H
4 -CH (CH 3 B. 2013 4-CF 2
CHF
2
-C
6
H
4 -CH (CH 3 B.2014 2-CHF 2
-C
6
H
4
-CH(CH
3 B.2015 3-CHF 2
-C
6
H
4 -CH (CH 3 B. 2016 4-CHF 2
-C
6
H
4 -CH (CH 3 1007 nptaen1y-HC3 B.2018 naphthalen-1-yl-CH(CH 3 B. 2018 nphthaln-2-yl-CH(CH 3 B. 2019 pyridin-2-yl-CH (CH 3 is B.2021 pyridin-3--yl-CH(CH 3 B.2022 pyridi-4yi--yl-CH(CH 3 B. 2022 5-CH 3 -pyridin-2-yl-CH(CH 3 B. 2023 6-CH 3 -pyridin-2-yl-CH(CH 3 B. 2024 5-CH 3 -pyridin-3-yl-CH(CH 3 2025 6-CH 3 -pyridin--yl-CH(CH 3 B.2027 5-OCH 3 -pyridin-2-yl-CH
(CH
3 B. 2027 6-OCH 3 -pyridin-2-yl-CH(CH 3 B.2 028 5-OCH 3 -pyridin-3-yl-CH(CH 3 B.2030 6-CH-pyridin---yl-CH(CH 3 B.2031 4-C1-pyridin-2-yl-CH(CH 3 B. 2031 5-C1-pyridin-2-yl-CH(CH 3 B.2033 6-Cl-pyridin-2-yl-CH(CH 3 B. 2033 2-C1-pyridin-3-yl-CH(CH 3 B.2035 6-Cl-pyridin-3-yl-CH(CH 3 B. 2035 6-Cl-pyridin-3-yl-CH(CH 3 B.2 036 2,-C1-pyridin--yl-CH(CH B.2038 3, -C1-yidin-2-yl-CH(CH 3 35B.2039 4-pyrimidin-2-yl-CH(CH 3 B. 2039 4-Cl-pyrimidin-2-yl-CH(CH 3 B.2041 5-CH3-pyrimidin-2-yl-CH(CH 3 B. 2041 4-CH 3 -pyrimidin-2-yl-CH(CH 3 2042 5-CH 3 -pyrimidin-2-yl-CH(CH 3 B. 2043 4-OCH 3 -pyrimidin-2-yl-CH(CH 3 B.2045 5-OCH 3 i--pyimdi-2-yCH cH 3 B.2046 2-pyrimidin-4-yl-CH(CH 3 B. 2046 2-C1-pyrimidin-4-yl-CH(CH 3 B.2048 I26-C1-pyrimidin-4-yl-CH
(CH
0"0 82 1 y im d n 4 y H C 3 0050/46043 258 No.
R
3 B.2049 2-CH 3 -pyrimidin-4-yl-CH(CH 3 B.2050 6-CH 3 -pyrimidin-4-yl-CH(CH 3 B.2051 2-OCH 3 -pyrimidin-4-yl-CH(CH 3 B .2052 6-OCH 3 -pyrimidin-4-yl-CH (CH 3 B .2053 pyrimidin-5-yl-CH (CH 3 B.2 054 2-C1-pyrimidin-5-yl-CH(CH 3 B .2055 2-CH 3 -pyrimidin-5-yl-CH (CH 3 B.2 056 2-OCH 3 -pyrimidin-5-yl-CH(CH 3 B.2 057 2-OCH 2
CH
3 -pyrimidin-5-yl-CH (CH 3 B.2058 furan-2-yl-CH(CH 3 B.2 059 4-Br-furan-2-yl-CH(CH 3 B.2 060 4-C1-furan-2-yl-CH(CH 3 B.2061 4-CN-furan-2-yl-CH (CH 3 B .2062 4-CH 3 -furan-2-yl-CH (CH 3 B.2063 5-Br-furan-2-yl-CH(CH 3 B .2064 5-C1-furan-2-yl-CH (CH 3 B.2065 5-CN-furan-2-yl-CH (CH 3 B. 2066 5-CH 3 -furan-2-yl-CH(CH 3 B.2067 furan-3-yl-CH(CH 3 B.2068 5-Br-furan-3-yl-CH(CH 3 B.2069 5-C1-furan-3-yl-CH(CH 3 B.2070 5-CN-furan-3-yl-CH(CH 3 B .2071 5-CH 3 -furan-3-yl-CH (CH 3 B.2072 thien-2-yl-CH(CH 3 B.2073 4-Br-thien-2-yl-CH(CH 3 B.2074 4-C1-thien-2-yl-CH(CH 3 B .2075 4-CN-thien-2-yl-CH (CH 3 B .2076 4-CH 3 -thien-2-yl-CH (CH 3 B.2 077 5-Br-thien-2-yl-CH(CH 3 B.2 078 5-C1-thien-2-yl-CH(CH 3 B .2079 5-CN-thien-2-yl-CH (CH 3 B .2080 5-CH 3 -thien-2-yl-CH (CH 3 B.2081 thien-3-yl-CH(CH 3 B. 2082 5-Br-thien-3-yl-CH(CH 3 B.2083 5-C1-thien-3-yl-CH(CH 3 B.2 084 5-CN-thien-3-yl-CH (CH 3 B.2085 5-CH 3 -thien-3-yl-CH (CH 3 B.2 086 oxazol-2-yl-CH(CH 3 B.2087 I4-Br-oxazol--2-yl-CH(CH 3 0050/ 46043 259 No.
R
B. 2088 4-C1-oxazol-2-yl-CH(CH 3 B.2089 4-CN-oxazol-2-yl-CH
(CH
3 B.2090 4-CH 3 -oxazol-2-yl-CH(CH 3 B.2091 5-Br-oxazol-2-yl-CH
(CH
3 B.2092 5-C1-oxazol-2-yl-CH(CH 3 B.2093 5-CN-oxazol--2-yl-CH(CH 3 B.2 094 5-CH 3 -oxazol-2-yl-CH (CH 3 1 00 5o a o 4 y H C 3 B.2096 2-oxazol-4-yl-CH(
CH
3 B.2097 2-Br-oxazol-4-yl-CH
(CH
3 B.2098 2-C1-oxazol-4-yl-CH
(CH
3 B. 2098 2-CH3-oxazol-4-yl-CH(CH 3 B.2100 2-C6H-oxazol-4-yl-CH(CH 3 B.2 100 2-C6H-oxazol-4-yl-CH
(CH
3 B.2 101 5-Cr-oxazol-4-yl-CH
(CH
3 B. 2102 5-C1-oxazol-4-yl-CH(CH 3 B.2104 5-CN3-oxazol-4-yl-CH(CH 3 B.2 104 5-CH 3 l-xazl-4-ylCH(H 3 B.2106 4-oxazol-5-yl-CH(CH 3 B. 2106 4-Br-oxazol-5-yl-CH(CH 3 B.2108 4-CN-oxazol-5-yl-CH(CH 3 B.2 108 4-CN3-oxazol-5-yl-CH
(CH
3 B.2110 4-CH-oxazol-5-yl-CH
(CH
3 B. 2110 2-Br-oxazol-5-yl-CH(CH 3 B.2112 2-C1-oxazol-5-yl-CH(CH 3 B.2113 2-CH3-oxazol-5-yl-CH(CH 3 B.2 113 2-oxazol--l--CH~ 3 B. 2114 4-isoxazol-3-yl-CH(C B. 2115 4-Br-isoxazol-3-yl-CH(CH 3 B.2117 4-CN-isoxazol-3-yl-CH(CH 3 B. 2117 4-CN3-isoxazol-3-yl-CH(CH 3 B. 2118 4-CH-isoxazol-3-yl-CH(CH 3 B.2 119 5-Br-isoxazol-3-yl-CH(CH 3 B.2121 5-C1-isoxazol-3-yl-CH(CH 3 B .2121 5-CH3-isoxazol-3-yl-CH
(CH
3 B. 2122 5-CH3z-oazl-C-ylCH cH 3 B.2124 3-isoxazol-4-yl-CH(CH 3 B.2 124 3-Br-isoxazol-4-yl-CH
(CH
3 B. 2126 3-CN-isoxazol-4-yl-CH(CH 3 0050/46043 260 No. R 3 B .2127 3-CH 3 -isoxazol-4-yl-CH (CH 3 B.2128 5-Br-isoxazol-4-yl-CH(CH 3 B.2129 5-Cl-isoxazol-4-yl-CH(CH 3 B. 2130 5-CN-isoxazol-4-yl-CH(CH 3 B. 2131 5-CH 3 -isoxazol-4-yl-CH(CH 3 B.2132 3,5-(CH 3 2 -isoxazol-4-yl-CH(CH 3 B.2 133 isoxazol-5-yl-CH
(CH
3 B.2134 3-Br-isoxazol-5-yl-CH(CH 3 B.2135 3-Cl-isoxazol-5-yl-CH(CH 3 B.2136 3-CN-isoxazol-5-yl-CH(CH 3 B. 2137 3-CH 3 -isoxazol-5-yl-CH(CH 3 B.2 138 3-C 6
H
5 -isoxazol-5-yl-CH(CH 3 B.2139 4-Cl, 3-C 6
H
5 -isoxazol-5-yl-CH(CH 3 BZ.140 4-Br, 3-C 6
H
5 -isoxazol-5-yi-CH (CH 3 B. 2141 4-Br-isoxazol-5-yl-CH(CH 3 B.2142 4-Cl-isoxazol-5-yl-CH(CH 3 B .2143 4-CN-isoxazol-5-yl-CH
(CH
3 B. 2144 4-CH 3 -isoxazol-5-yl-CH(CH 3 B. 2145 thiazol-2-yl-CH(CH 3 B.2146 4-Br-thiazol-2-yl-CH(CH 3 B .2147 4-Cl-thiazol-2-yl-CH (CH 3 B.2 148 4-CN-thiazol-2-yl-CH
(CH
3 B.2 149 4-CH 3 -thiazol-2-yl-CH(CH 3 B. 2150 5-Br-thiazol-2-yl-CH(CH 3 B.2151 5-Cl-thiazol-2-yl-CH(CH 3 B. 2152 5-CN-thiazol-2-yl-CH
(CH
3 B. 2153 5-CH 3 -thiazol-2-yl-CH(CH 3 B.2154 thiazol-4-yl-CH(CH 3 B .2155 2-Br-thiazol-4-yl-CH
(CH
3 B.2 156 2-C l-thiazol-4-yl-CH
(CH
3 B.2 157 2-CN-thiazol-4-yl-CH(CH 3 B.2158 2-CH 3 -thiazol-4-yl-CH(CH 3 B.2 159 5-Br-thiazol-4-yl-CH(CH 3 B .2160 5-Cl-thiazol-4-yl-CH
(CH
3 B .2161 5-CN-thiazol-4-yl-CH
(CH
3 B.2 162 5-CH 3 -thiazol-4-yl-CH (CH 3 B. 2163 thiazol-5-yl-CH (CH 3 B.2 164 4-Br-thiazol-5-yl-CH(CH 3 B.2165 4-Cl-thiazol-5-yl-CH(CH 3 44 0050/46043 261 No. R B.2166 4-CN-thiazol-5-yl-CH(CH 3 B.2 167 4-CH3-thiazol-5-yl-CH(CH 3 B.2168 2-Br-thiazol-5-yl-CH(CH 3 B.2169 2-C1-thiazol-5-yl-CH(CH 3 B.2 170 2-CN-thiazol-5-yl-CH
(CH
3 B.2171 2-CH 3 -thiazol-5-yl-CH
(CH
3 B.2 172 isothiazol-3-yl-CH (CH 3 101 34 B -i o h a o -3 y H C 3 B.2174 4-Br-isothiazol-3-yl-CH(CH 3 B.2175 4 -Cl-isothiazol-3-yl-CH(CH 3 B.2176 4-CN3-isothiazol-3-yl-CH(CH 3 B. 2176 4-CH-isothiazol-3-yl-CH(CH 3 B. 2177 5-Br-isothiazol-3-yl-CH
(CH
3 B. 2-17 5-C 1-sothiazol-3-yl-CH
(CH
3 B. 2179 5-CN3-iSOtha -3-yl-CH (CH 3 B. 2180 53isothiazol--ylCH cH B.2182 3-isothiazol-4-yl-CH(CH 3 B. 2182 3-Br-isothiazol-4-yl-CH
(CH
3 B. 2183 3 -Cl-isothiazol-4-yl-CH(CH 3 B.2 184 3-CN3-isothiazol-4-yl-CH (CH 3 B.2186 5-CH-isothiazol-4-yl-CH(CH 3 B.2 186 5-Br-isothiazol-4-yl-CH
(CH
3 B. 2187 5-C1-isothiazol-4-yl-CH(CH 3 B. 2188 5-CN3-isothiazol-4-yl-CH
(CH
3 B.2190 3 5- CH 3 -isothiazol-4-yl-CH
(CH
3 B.2191 3 ,5(Chia)2-sot-Hiaol4-l-H(H B.2 191 3-isothiazol-5-yl-CH
(CH
3 B.2 192 3-Br-isothiazol-5-yl-CH
(CH
3 B.2194 3 -C1-isothiazol-5-yl-CH(CH 3 35B.2195 3 -CH3-isothiazol-5-yl-CH(CH 3 B.2 195 4-CH-isothiazol-5-yl-CH
(CH
3 B. 2196 4-Br-isothiazol-5-yl-CH
(CH
3 B.2 197 4-C1-isothiazol-5-yl-CH
(CH
3 B.2 198 4-CN3-isothiazol-5-yl-CH
(CH
3 B.220 19 -Cmiothial-5-ylCH
(CH
3 B. 2200 I-imidazol-2-yl CH(CH3 B.2202 1-C1-imidazol-2-yl-CH(CH 3 B.2203 1-Br-imidazol-2-yl-CH
(CH
3 B. 2204 1-CH 3 -imidazol-2-yl-CH(CH 3 '1 0050/46043 262 No.
R
B.2205 4-C1-imidazol-2-yl-CH(CH 3 B.2206 4-Br-imidazol-2-yl-CH(CH 3 B.2207 4-CN-imidazol-2-yl-CH(CH 3 B. 2208 4-CH 3 -imidazol-2-yl-CH
(CH
3 B.2209 1-CH 3 5-C1-imidazol-2-yl-CH(CH 3 B.2210 1,4-(CH 3 2 -iMidazol-2-yl-CH(CH 3 B.2211 1, 5- (CH 3 2 -imidazol-2-yl-CH (CH 3 1022 iiaol4y-HC3 B.2213 2-imidazol-4-ylCH(CH3 B.2214 2-C1-imidazol-4-yl-CH(CH 3 B.2215 2-Br-imidazol-4-yl-CH
(CH
3 B.2216 2-CH3-imidazol-4-yl-CH(CH 3 B.2217 1-CH 3 -imidazol-4-yl-CH(CH 3 B .2217 2-CH-imidazol-4-yl-CH
(CH
3 B.2219 5-C 1-imidazol-4-yl-CH
(CH
3 B.2220 5-Br- imidazol-4-yl-CH (CH 3 20B.2221 5-CN3-imidazol-4-yl-CH(CH 3 B.2222 5-CH 3 -mdl-4-yazl-H CH H3 B.2223 1,-CH 3 -C-imidazol-4-yl-CH(CH 3 B.2224 1,2-(CH 3 2 -iMidazol-4-yl-CH(CH 3 B.2225 py,5-(C 3 -imidzol4-y-CHcH B.2225 5-pyrazol-3-yl-CH(CH 3 B.2227 5-Br-pyrazol-3-yl-CH
(CH
3 B.2228 5-C1-pyrazol-3-yl-CH(CH 3 B.2229 5-CN-pyrazol-3-yl-CH(CH 3 B.2230 5-C6H5-pyrazol-3-yl-CH(CH 3 B .2230 1-C 6 H-pyrazol-3-yl-CH
(CH
3 B.2232 4-Br-pyrazol-3-yl-CH(CH 3 B.2233 4-C 1-pyrazol-3-yl-CH
(CH
3 35B.2234 4-CN3-pyrazol-3-yl-CH(CH 3 B.2235 4-CH 3 -pyrazol-3-yl-CH
(CH
3 B.2236 1-CH 3 -pyrazol-3-yl (CH 3 B.2237 1,4-(C11 3 2 -pyrazol-3-yl-CH(CH 3 40B.2238 1,-CH 3 2 -C-pyrazol-3-yl-CH(CH 3 B.2239 1-CH 3 4-C1-pyrazol-3-yl-CH(CH 3 B.2240 -C,C-pyrazol--yl-CH(CH 3 B.2241 3-pyrazol-4-yl-CH(CH3 B.2242 3-Br-pyrazol-4-yl-CH
(CH
3 B.2243 .3-CN-pyrazol-4-yl-CH(CH 3 0050/46043 is 263 No. R 3 B. 2244 3-CH 3 -pyrazol-4-yl-CH(CH 3 B.2245 I-CH 3 -pyrazol-4-yl-CH
(CH
3 B.2246 1, 5- (CH 3 2 -pyrazol-4-yl-CH
(CH
3 B.2247 1,3-(CH3)2-pyrazol-4-yl-CH(CH 3 B.2248 1-CH 3 3-Cl-pyrazol-4-yl-CH(CH 3 B.2249 1-CH 3 5-C1-pyrazol-4-yl-CH(CH 3 B. 2250 pyrazol-5-yl-CH(CH 3 B. 2251 3-Br-pyrazol-5-yl-CH(CH 3 B. 2252 3-C1-pyrazol-5-yl-CH
(CH
3 B.2253 3-CN-pyrazol-5-yl-CH
(CH
3 B.2254 3-CH 3 -pyrazol-5-yl-CH
(CH
3 B.2255 I-CH 3 -pyrazol-5-yl-CH
(CH
3 B .2256 4-Br-pyrazol-5-yl-CH
(CH
3 B. 2257 4-Cl-pyrazo.l-5-yi-CH(CH 3 B. 2258 4-CN-pyrazol-5-yl-CH(CH 3 B.2259 4-CH 3 -pyrazol-5-yl-CH(CH 3 B.2260 1,3-(CH 3 2 -pyrazol-5-yl-CH(CH 3 B.2261 1,4-(CH 3 2 -pyrazol-5-yl-CH(CH 3 B. 2262 1-CH 3 3-C1-pyrazol-5-yl-CH(CH 3 B. 2263 1-CH 3 4-Cl-pyrazol-5-yl-CH(CH 3 B.2264 1,3, 4-oxadiazol-5-yl-CH
(CH
3 B.2265 2-CH3-1,3,4-oxadiazol-5-yl-CH(CH 3 B.2266 2-CF3-1,3,4-oxadiazol-5-yl-CH(CH 3 B.2267 2-OCH 3 3, 4-oxadiazol-5-yl-CH(CH 3 B.2268 2-Cl-1,3,4-oxadiazol-5-yl-CH(CH 3 B.2269 2-CH(CH 3 2 -1,3,4-oxadiazol-5-yl-CH(CH 3 B.2270 1,3,4-oxadiazol-2-yl-CH(CH 3 B.2271 5-CH3-1,3,4-oxadiazol-2-yl-CH(CH 3 B.2272 5-CF3-1,3,4-oxadiazol-2-yl-CH(CH 3 B.2273 5-OCH 3 -1,3,4-oxadiazol-2-yl-CH(CH 3 B.2274 5-Cl-1,3,4-oxadiazol-2-yl-CH(CH 3 B.2275 5-CH(CH 3 2 -1,3,4-oxadiazol-2-yl-CH(CH 3 B.2276 5-C 6
H
5 -1,3,4-oxadiazol-2-yl-CH(CH 3 B.2277 1,2,4-oxadiazol-3-yl-CH(CH 3 B.2278 5-CH 3 -1,2,4-oxadiazol-3-yl-CH(CH 3 B.2279 5-CF 3 -1,2,4-oxadiazol-3-yl-CH(CH 3 B.2280 5-OCH 3 -1,2,4-oxadiazol-3-yl-CH(CH 3 B.2281 5-Cl-1,2,4-oxadiazol-3-yl-CH(CH 3 B.2282 5-CH(CH 3 2 -1,2,4-oxadiazol-3-yl-CH(CH 3 0050/46043 264 N~o. R 3 B.2283 1,2,4-triazol-3-yl-CH(CH 3 B.2284 1-CH3-1,2,4-triazol-3-yl-CH(CH 3 B.2285 5-CH3-1,2,4-triazol-3-yl-CH(CH 3 B.2286 5-CF 3 -1,2,4-triazol-3-yl-CH(CH 3 B.2287 5-OCH3-1,2,4-triazol-3-yl-CH(CH 3 B.2288 5-C1-1,2,4-triazol-3-yl-CH(CH 3 B.2289 5-CH(CH 3 2 -1,2,4-triazol-3-yl-CH(CH 3 B.2290 I-C6H5-1,2,4-triazol-3-yl-CH(CH 3 B.2291 1,3,4-thiadiazol-5-yl-CH(CH 3 B.2292 2-CH 3 4-thiadiazol-5-yl-CH(CH 3 B.2293 2-CF3-1,3,4-thiadiazol-5-yl-CH(CH 3 B.2294 2-OCH3-1,3,4-thiadiazol-5-yl-CH(CH 3 B.2295 2-CH2OCH 3 4-thiazol-5-yl-CH
(CH
3 B2961 2-Cl-1,3,4-thiadiazoi-5-yl-CH(CH 3 B.2297 2-CH(CH 3 2 -1,3,4-thiadiazol-5-yl-CH(CH 3 B.2298 1,3,4-thiadiazol-2-yl-CH(CH 3 B.2299 5-CH 3 -1,3,4-thiadiazol-2-yl-CH(CH 3 B.2300 5-CF 3 -1,3 ,4-thiadiazol-2-yl-CH(CH 3 B.2301 5-OCH 3 4-thiadiazol-2-yl-CH(CH 3 B.2302 5-Cl-1,3,4-thiadiazol-2-yl-CH(CH 3 B.2303 5-CH(CH 3 2 -1,3,4--thiadiazol-2-yl-CH(CH 3 B.2304 5-C6H 5 -1,3,4-thiadiazol-2-yl-CH(CH 3 B.2305 1,2,4-thiadiazol-3-yl-CH(CH 3 B.2306 5-CH 3 4-thiadiazol-3-yl-CH(CH 3 B.2307 5-CF 3 -1,2,4-thiadiazol-3-yl-CH(CH 3 B.2308 5-OCH 3 -1,2,4-thiadiazol-3-yl-CH(CH 3 B.2309 5-Cl-1,2,4-thiadiazol-3-yl-CH(CH 3 B.2310 5-CH(CH 3 )2-1,2,4-thiadiazol-3-yl-CH(CH 3 B.2311 pyrrol-2-yl-CH(CH 3 B.2312 4-C1-pyrrol-2-yl-CH(CH 3 B. 2313 4-Br-pyrrol-2-yl-CH(CH 3 B .2314 4-CH3-pyrrol-2-yl-CH
(CH
3 B.2315 4-C 6
H
5 -pyrrol-2-yl-CH(CH 3 B.2316 benzimidazol-2-yl-CH
(CH
3 B. 2317 quinolin-2-yl-CH(CH 3 B.2318 2-F-C 6
H
4
-OCH(CH
3 B.2319 3-F-C 6
H
4
-OCH(CH
3 B.2320 4-F-C 6
H
4
OCH(CH
3 B.2321 2,3-F 2
-C
6
H
3
-OCH(CH
3
Y
0050/46043 265 'v No. R B.2322 2,4-F 2
-C
6
H
3
-QCH(CH
3 B.2323 2,5-F 2
-C
6
H
3
-OCH(CH
3 B.2324 2,6-F 2
-C
6
H
3
-OCH(CH
3 B.2325 3,4-F 2
-C
6
H
3
-OCH(CH
3 B.2326 3,5-F 2
-C
6
H
3
-OCH(CH
3 B.2327 2-Cl-C 6
H
4
-OCH(CH
3 B.2328 3-Cl-C 6
H
4
-OCH(CH
3 B.2329 4-C1-C 6
H
4
-OCH(CH
3 B.2330 2,3-C1 2
-C
6
H
3
-OCH(CH
3 B.2331 2,4-C1 2
-C
6
H
3
-OCH(CH
3 B.2332 2,5-C1 2
-C
6
H
3
-OCH(CH
3 B.2333 2, 6-C1 2
-C
6
H
3
-OCH(CH
3 B.2334 3,4-c1 2
-C
6
H
3
-OCH(CH
3 B.2335 3,5-Cl 2
-C
6
H
3
-OCI(CH
3 B.2336 2,3,4-Cl 3
-C
6
H
2
-QCH(CH
3 B.2337 2,3,5-C1 3
-C
6
H
2
-OCH(CH
3 B.2338 2,3,6-Cl 3
-C
6
H
2
-OCH(CH
3 B.2339 2,4,5-C1 3
-C
6
H
2
-OCH(CH
3 B.2340 2,4,6-Cl 3
-C
6
H
2
-OCH(CH
3 B.2341 3,4,5-C1 3
-C
6
H
2
-OCH(CH
3 B.2342 2-Br-C 6
H
4
-OCH(CH
3 B.2343 3-Br-C 6
H
4
-OCH(CH
3 B.2344 4-Br-C 6
H
4
-OCH(CH
3 B.2345 2, 3-Br 2
-C
6
H
3
-OCH(CH
3 B.2346 2,4-Br 2
-C
6
H
3
-QCH(CH
3 B.2347 2,5-Br 2
-C
6
H
3
-OCH(CH
3 B.2348 2, 6-Br 2
-C
6
H
3
-OCH(CH
3 B.2349 3,4-Br 2
-C
6
H
3
-OCH(CH
3 B .2350 3, 5-Br 2
-C
6
H
3 -OCH (CH 3 B.2351 2-F, 3-C1-C 6
H
3
-OCH(CH
3 B.2352 2-F, 4-Cl-C 6
H
3
-OCH(CH
3 B.2353 2-F, 5-C1-C 6
H
3
-OCH(CH
3 B.2354 2-F, 3-Br-C 6
H
3
-OCH(CH
3 B.2355 2-F, 4-Br-C 6
H
3
-OCH(CH
3 B.2356 2-F, 5-Br-C 6
H
3
-OCH(CH
3 B.2357 2-Cl, 3-F-C 6
H
3
-OCH(CH
3 B.2358 2-Cl, 4-F-C 6
H
3
-OCH(CH
3 B.2359 2-Cl, 5-F-C 6
H
3
-OCH(CH
3 0050/46043 266 No.
R
B.2360 2-Cl, 3-Br-C 6
H
3
-OCH(CH
3 B.2361 2-Cl, 4-Br-C 6
H
3
-OCH(CH
3 B.2362 2-Cl, 5-Br-C 6
H
3
-OCH(CH
3 B.2363 2-Br, 3-F-C 6
H
3
-OCH(CH
3 B.2364 2-Br, 4-F-C 6
H
3
-QCH(CH
3 B.2365 2-Br, 5-F-C 6
H
3
-OCH(CH
3 B.2366 2-Br, 3-Cl-C 6
H
3
-OCH(CH
3 B.37 2B,4CC63OHC3 B.2368 2-Br, 4-Cl-C 6
H
3
-OCH(CH
3 B.2369 4-Cl, 3,5-Br 2
-C
6
H
2
-OCH(CH
3 B.2370 2-CN-C 6
H
4
-OCH(CH
3 B.2371 3-CN-C 6
H
4
-OCH(CH
3 B.2372 4-CN-C 6
H
4
-OCH(CH
3 B.2373 2-N0 2
-%C
6
H
4
-OCH(CH
3 B .2374 3-N0 2
-C
6
H
4
-OCH(CH
3 B.2375 4-N0 2
-C
6
H
4
-OCH(CH
3 B.2376 2-CH 3
-C
6
H
4
-OCH(CH
3 B. 2377 3-CH 3
-C
6
H
4
-QCH(CH
3 B.2378 4-CH 3
-C
6
H
4
-OCH(CH
3 B.2379 2, 3- (CH 3 2
-C
6
H
3 -OCH (CH 3 B.2380 2,4-(CH 3 2
-C
6
H
3
-OCH(CH
3 B.2381 2,5-(CH 3 2
C
6
H
3
-OCH(CH
3 B.2382 2, 6- (CH 3 2
-C
6
H
3 -OCH (CH 3 B.2383 3,4-(CH 3 2
-C
6
H
3
-OCH(CH
3 B.2384 3, 5- (CH 3 2
-C
6
H
3 -OCH (CH 3 B. 2385 2-CH 2
CH
3
-C
6
H
4 -OCH (CH 3 B. 2386 3-CH 2
CH
3
-C
6
H
4 -OCH (OH 3 B .2387 4-CH 2
CH
3
-C
6
H
4 -OCH CH 3 B.2388 2-CH (CH 3 2
-C
6
H
4 -OCH (CH 3 B.2389 3-CH(CH 3 2
-C
6
H
4
-OCH(CH
3 B.2390 4-CH(CH 3 2
-C
6
H
4
-OCH(CH
3 B.2391 3-C(CH 3 3
-C
6
H
4
-OCH(CH
3 B.2392 4-C(CH 3 3
-C
6
H
4
-OCH(CH
3 B.2393 2-C 6
H
5
-C
6
H
4
-OCH(CH
3 B.2394 3-C 6
H
5
-C
6
H
4
-OCH(CH
3 B.2395 4-C 6
HS-C
6
H
4 -OCH (CH 3 B. 2396 2-OCH 3
-C
6
H
4
-OCH(CH
3 4 53 73 O C 3 C H -O H C 3 B. 2397 3-0CH 3
-C
6
H
4
-OCH(CH
3 r.39 4-C 3 6 4
-V(C
0050/46043 ____267 No. R 3 B.2399 2, 3- (OCHi 3 2
-C
6
H
3 -OCH (CH 3 B.2400 2 4- (OCH 3 2
-C
6
H
3 -QCH (CH 3 B.2401 2, 5- (OCH 3 2
-C
6
H
3 -OCH (CH 3 B.2402 2, 6- (OCH 3 2
-C
6
H
3 -OCH (CH 3 B.2403 3,4-(OCH 3 2
-C
6
H
3
-OCH(CH
3 B.2404 3 5- (OCH3) 2-C 6
H
3 -OCH (CH 3 B.2405 3 4 (OCH3) 3
-C
6
H
2 -OCH (CH 3 104 62 OC 2 H 6 4- C C 3 B.2407 2-OCH2CH 3
-C
6
H
4
-OCH(CH
3 B .2407 3-OCH 2
CH
3
-C
6 11 4 -OCH CH 3 is B.2408 2-0OCH) 2
CH
3
-C
6
H
4 -OCH CH 3 B.240 3-0 (CH2) 2 CH3-C 6
H
4 -OCH (CH 3 B.2411 4-O(CH2) 2
CH
3
-C
6
H
4
-OCH(CH
3 B.2412 4-OC(CH) 2
C-
6
H
4 -OCH (CH 3 B.2413 2-OCH (CH 3 2
-C
6
H
4 :-OCH (CH 3 B.2414 4-OCH(CH 3 2
-C
6
H
4
-OCH(CH
3 B.2415 3-OC(CH 3 3-C 6
H
4 -OCH (CH 3 B.2416 3-OC(CH 3 3
-C
6
H
4
-OCH(CH
3 B.2417 4-OC(2CH=CH-C 6
H
4 -OCH (CH 3 B.2418 2-OCH 2
CH=CH
2
-C
6
H
4 -OCH (CH 3 B.2418 4-OCH 2
CH=CH
2
-C
6
H
4 -OCH (CH 3 B.2420 2-CF23H-C 6
H
4
OCH(CH
3 B.2421 2-CF 3
-C
6
H
4
-OCH(CH
3 B.2422 4-CF 3
-C
6
H
4
-OCH(CH
3 B.2424 4-CF2 3
-C
6
H
4
-OCH(CH
3 B.2425 2-CO 2
CH
3
-C
6
H
4 -OCH (CH 3 B.2426 3-CO2 2
CH
3
-C
6
H
4 -OCH (CH 3 B.2427 4-CO2CH2C 3
-C
6
H
4 -OCH (CH 3 B.2428 2-CO 2
CH
2
CH
3
-C
6
H
4 -OCH (CH 3 B.2429 2-CO2CH 2
C-C
6
H
4
-OCH(CH
3 B.2430 4-CO2H 2
CH
6
H
4
-OCH(CH
3 B.2431 2-CON H 2
-C
6
H
4
-OCH(CH
3 B.2432 2-CON(H 2
-C
6
H
4
-OCH(CH
3 B.2433 4-CON(H 2
-C
6
H
4
-OCH(CH
3 B.2434 2-CON(CH 3 2
-C
6
H
4
OCH(CH
3 B.2435 2-CON(CH 3
)-C
6
H
4
-OCH(CH
3 B.2436 4CON(CH 3
)-C
6
H
4 -OCH (CH 3 B.2437 3CNC- 6
H-OCH(CH
3 B.2437 4-CONHCH 3
-C
6
H
4
-C(H)
0050/46043 ____268 No. R B.2438 2-NH 2
-C
6
H
4 -OCH (CH 3 B.2439 3-NH 2
-C
6
H
4 -OCH (CH 3 B.2440 4-NH 2
-C
6
H
4
-OCH(CH
3 B.2441 2-N (CH 3 2
-C
6
H
4 -OCH (CH 3 B.2442 3-N (CH 3 2
-C
6
H
4 -OCH (CH 3 B.2443 4-N (CH 3 2
-C
6
H
4 -OCH (CH 3 B.2444 2-NHCH 3
-C
6
H
4 -OCH (CH 3 1 04 53 N C 3 6 4 O H C 3 B. 2445 3-NHCH 3
-C
6
H
4
-OCH(CH
3 B. 2446 4-CNHH-C 6
H
4
-OCH(CH
3 B.2448 2-CSNH 2
-C
6
H
4 -OCH (CH 3 B.24498 3-CSNH 2
-C
6
H
4
-OCH(CH
3 B.2450 2-SCH-C 6
H
4
-OCH(CH
3 B.2450 2-SCH 3
-C
6
H
4
-OCH(CH
3 B. 2451 4-SCH 3
-C
6
H
4
-OCH(CH
3 B.2453 4-SCH 3
-C
6
H
4
-OCH(CH
3 B.2454 2-SOCH 3
-C
6
H
4
-OCH(CH
3 B.2455 3-SOCH 3
-C
6
H
4
-OCH(CH
3 B.2456 4-SO2CH 3
-C
6
H
4
-OCH(CH
3 B.2457 2-SO2CH 3
-C
6
H
4
-OCH(CH
3 B.2458 4-SO2CH 3
-C
6
H
4 -OCH (CH 3 B.2459 4-OC 3
-C
6
H
4
-OCH(CH
3 B.2460 2-OCF 3
-C
6
H
4
-OCH(CH
3 B.2461 4-OCF 3
-C
6
H
4
-OCH(CH
3 B.2462 2-OCHF 2
-C
6
H
4
-OCH(CH
3 B.2463 3-OCHF 2
-C
6
H
4 -OCH (CH 3 B.2464 4
-OCHF
2
-C
6
H
4
-OCH(CH
3 B.2465 3-CF 3 4-OCF 3
-C
6
H
3
-OCH(CH
3 B.2466 2-CH2CH 2
F-C
6
H
4
-OCH(CH
3 B.2467 3-CH2CH 2
F-C
6
H
4 -OCH (CH 3 B.2468 4-CH 2
CH
2
F-C
6
H
4
-OCH(CH
3 B.2469 2-CH 2
CF
3
-C
6
H
4 -OCH (CH 3 B.2470 3-CH 2
CF
3
-C
6
H
4 -OCH (CH 3 B.2471 4-CH2CF 3
-C
6
H
4
-OCH(CH
3 B. 2472 2-CF2CHF 2
-C
6
H
4 -OCH (CH 3 B.2473 3-CF 2
CHF
2
-C
6
H
4 -OCH (CH 3 B.2474 4-CF2CHF 2
-C
6
H
4 -OCH (CH 3 B.2475 2-CHF 2
-C
6
H
4 -OCH (CH 3 B.2476 3-H 2
CH-OCH(CH
3 13CF2CH 0050/46043 269 No.
R
B. 2477 4-CHF 2 0 6
H
4
-OCH(CH
3 B.2478 naphthalen-1-yl-OCH(CH 3 B.2479 naphthalen-2-yl-OCH(CH 3 B .2480 pyridin-2-yl-OCH
(CH
3 B. 2481 pyridin-3-yl-OCH
H
3 B.2482 pyridin-4-yl-OCH(CH 3 B.2483 5-CH 3 -pyridin-2-yl-OCH (CH 3 1 04 46 C 3 p r d i l O H C 3 B.2484 6-CH 3 -pyridin-2-yl-OCH
(OH
3 B.2486 6-CH 3 -pyridin-3-yl-OCH
(OH
3 B .2487 5-OCH 3 -pyridin-2-yl-OCH
(CH
3 B.2488 6-00H 3 -pyridin-2-yl-OCH(CH 3 B .2489 5-00H 3 -pyridin-3-yl-OCH
(CH
3 B.2490 6-00H 3 -pyridin-3-yl-OCH
(CH
3 B.2491 4-C1-pyridin-2-yl-OCH H3) B .2492 5-C1-pyridin-2-yl-OCH (CH 3 B .2493 6-Cl-pyridin-2-yl-OCH H3) B.2494 2-Cl-pyridin-3-yl-OCH(CH 3 B. 2495 5-Cl-pyridin-3-yl-OCH(CH 3 B.2496 6-C1-pyridin-3-yl-OCH(CH 3 B.2497 2-C1-pyridin-4-yl-OCH(CH 3 B.2498 3, 5-C1 2 -pyridin-2-yl-OCH(CH 3 B. 2499 pyrimidin-2-yl-OCH(CH 3 B. 2500 4-C1-pyrimidin-2-yl-QCH
(OH
3 B251-O-yiii---OHH) B. 2502 4-CH-pyrimidin-2-yl-OCH(CH 3 B .2503 5-CH 3 -pyrimidin-2-yl-OCH
(OH
3 B.2503 4-0H 3 -pyrimidin-2-yl-OCH(CH 3 B. 2505 5-OCH 3 -pyrimidin-2-yl-OCH
(OH
3 B.2505 4-OCH 2
O
3 -yrimidin-2-yl-OH(H 3 B .2507 5-OCH 2
CH
3 -pyrimidin-2-yl-OCH
(CH
3 B.2507 pyrimidin--yl-OCH
(OH
3 CHCH3 B.2508 2-pyrimidin-4-yl-OHoH 3 B.2510 6-C1-pyrimidin-4-yl-OCH
(OH
3 B.2511 2, 6-C1 2 -pyrimidin-4-y1-OCH(OH 3 B.2512 2-CH 3 -pyrimidin-4-yl-QOH
(OH
3 B.2513 6-OH 3 -pyrimidin-4-yl-OCH(OH 3 B.2514 2-00H 3 -pyrimidin-4-yl-OOH
(OH
3 B.2515 I6-00H 3 -pyrixnidin-4-yl-OOH
(OH
3 0050/46043 270 B. 56 R3HC 3 prmii--lOHc 3 B.2516 2-OCH 2
CH
3 -pyrimidin-4-yl-OCH
(CH
3 B.2517 Pyrimidin--yi-OCH--ylOCH 3 B.2518 2 -pyrimidin-5-yl-OCH(
H
3 B. 2520 2 -CH-pyrimidin-5-yl-OCH(CH 3 B.2520 2 -CH3-pyrimidin-5-yl-OCH
(CH
3 B.2521 2-OCCH 3 -pyrimidin-5-yl-OCH
(CH
3 B.52 2OHC3prmdn5yOC C3 B.2523 furan-2-yl-OCH
(CH
3 B. 2524 4-Br-furan-2-yl-OCH(CH 3 B.2525 4-Cl-furan-2-yl-OCH(CH 3 B. 2526 4-CN-furan-2-yl-OCH(CH 3 B.2527 4-CH 3 -furan-2-yl-OCH(CH 3 B. 2528 5-Br-furan-2-yl-OCH
(CH
3 B.2529 5=C-f -uran-2Z-yl-OCH(CH 3 B. 2530 5-CN-furan-2-yl-OCH(CH 3 B. 2531 5-CH 3 -furan-2-yl-OCH(CH 3 B.2532 furan-3-yl-OCH
(CH
3 B. 2533 5-Br-furan-3-yl-OCH(CH 3 B.2534 5-Cl-furan-3-yl-OCH(CH 3 B.2535 5-CN-furan-3-yl-OCH(CH 3 B.2 536 5-CH 3 -furan-3-yl-OCH
(CH
3 B .2537 thien-2-yl-OCH(CH 3 B. 2538 4-Br-thien-2-yl-OCH(CH 3 B.2539 4-C1-thien-2-yl-OCH
(CH
3 B.2540 4-CN-thien-2-yl-OCH(CH 3 B.2541 4-CH3-thien-2-yl-OCH(CH 3 B .2542 5-Br-thien-2-yl-OCH
(CH
3 B. 2543 5-C1-thien-2-yl-OCH(CH 3 B.2544 5-CN-thien-2-yl-OCH(CH 3 B. 2545 5-CH3-thien-2-yl-OCH(CH 3 B.2546 thien-3-yl-OCH(CH 3 B.2 547 5-Br-thien-3-yl-OCH(CH 3 B.2548 5-C1-thien-3-yl-OCH(CH 3 B. 2549 5-CN-thien-3-yl-OCH(CH 3 B. 2550 5-CH 3 -thien-3-yl-OCH(CH 3 B. 2551 oxazol-2-yl-OCH(CH 3 B. 2552 4-Br-oxazol-2-yl-OCH(CH 3 455 34 C x zo l O H C 3 B. 2553 14-C1-oxazol-2-yl-OCH(CH 3 0050/46043 271 No.
R
3 B.2555 4-CH 3 -oxazol-2-yl-OCH(CH 3 B.2556 5-Br-oxazol-2-yl-OCH
(CH
3 B.2557 5-Cl-oxazol-2-yl-OCH(CH 3 B.2558 5-CN-oxazol-2-yl-OCH
(CH
3 B.2559 5-CH 3 -oxazol-2-yl-OCH(CH 3 B .2560 oxazol-4--yl-OCH(CH 3 B.2561 2-Br-oxazol-4-yl-OCH(CH3 1052 2C-xzo--lOHC3 B. 2562 2-C1-oxazol-4-yl-OCH(CH 3 B.2564 2-CN3-oxazol-4-yl-OCH(CH 3 B.2565 2-C6H5-oxazol-4-yl-OCH
(CH
3 B. 2565 2-C 6 H-oxazol-4-yl-OCH(CH 3 B.2567 5-Br-oxazol-4-yl-OCH
(CH
3 B.2568 5-C1-oxazol-4-yl-OCH(CH 3 B.2 568 5-CN3-oxazol-4-yl-OCH
(CH
3 B.2570 5-CH 3 -xzo-yl-OCH(CH 3 B.2571 4-oxazol-5-yl-OCH(CH 3 B .2571 4-Cr-oxazol-5-yl-OCH
(CH
3 B.2573 4-C 1-oxazol-5-yl-OCH (CH 3 B.2574 4-CN3-oxazol-5-yl-OCH(CH 3 B.2575 4-CH-oxazol-5-yl-OCH(CH 3 B.2576 2-Br-oxazol-5-yl-OCH
(CH
3 B.2577 2-C 1-oxazol-5-yl-OCH
(CH
3 B.2578 2-CN3-oxazol-5-yl-OCH(CH 3 B.2579 2-soxazol--yl-OCH(CH 3 30B.2580 4-isoxazol-3-yl-OCH(CH 3 B.2581 4-Cr-isoxazol-3-yl-OCH(CH 3 B.2582 4-CN-isoxazol-3-yl-OCH(CH 3 B.2583 4-CN3-isoxazol-3-yl-OCH(CH 3 B. 2583 4-CH-isoxazol-3-yl-OCH(CH 3 B.2585 5-Br-isoxazol-3-yl-OCH(CH 3 B.2586 5-C1-isoxazol-3-yl-OCH
(CH
3 B. 2586 5-CN3-isoxazol-3-yl-OCH(CH 3 B.2588 5-CH 3 z-xzo-yl-OCH(CH 3 B.2589 3-isoxazol-4-yl-OCH(CH 3 B .2590 3-Cr-isoxazol-4-yl-OCH(CH 3 B.2591 3-C 1-isoxazol-4-yl-OCH
(CH
3 B.2592 3-CH 3 -isoxazol-4-yl-OCH(CH 3 B.2593 5-Br-isoxazol-4-yl-OCH(CH 3 v 0050/46043 272 No. R 3 B.2594 5-Cl-isoxazol-4-yl-OCH(CH 3 B.2595 5-CN-isoxazol-4-yl-OCH
(CH
3 B. 2596 5-CH 3 -isoxazol-4-yl-OCH(CH 3 B.2597 3,5-(CH3)2-isoxazol-4-yl-OCH(CH 3 B. 2598 isoxazol-5-yl-OCH(CH 3 B. 2599 3-Br-isoxazol-5-yl-OCH(CH 3 B.2600 3-Cl-isoxazol-5-yl-OCH(CH 3 B 6110- s x zo l O H C 3 B. 2601 3-CH3-isoxazol-5-yl-OCH(CH 3 B .2602 3-C6H5-isoxazol-5-yl-OCH
(CH
3 B .2603 3-C 6
H
5 -isoxazol-5-yl-OCH(CH 3 B.2605 4-Cl, 3-C6H 5 -isoxazol-5-yl-OCH(CH 3 B.2606 4-Br, 3-C 6
H
5 -isoxazl-5-yl-oH(0H 3 sm.266 )4-isoxazol-5-yl-OCiH(CH 3 B.2608 4-C1-isoxazol-5-yi-OCH(CH 3 B.2609 4-CN3-isoxazol-5-yl-OCH(CH 3 B.2 610 4-hioxazl-5-ylCH cH 3 B.2611 4-thiazol-2-yl-OCH(CH 3 B .2611 4-Br-thiazol-2-yl-OCH
(CH
3 B.2613 4-Cl-thiazol-2-yl-OCH(CH 3 B.2613 4-CN3-thiazol-2-yl-OCH
(CH
3 B.2615 4-CH-thiazol-2-yl-OCH(CH 3 B .2615 5-Br-thiazol-2-yl-OCH
(CH
3 B .2616 5-C1-thiazol-2-yl-OCH
(CH
3 B. 2617 5-CH3-thiazol-2-yl-OCH
(CH
3 B.2619 5-h3ao-hiazl-2-yl-CHcH 3 B. 2619 2thiazol-4-yl
CH(C
B.2621 2-Br-thiazol-4-yl-OCH(CH 3 B.2622 2-Cl-thiazol-4-yl-OCH(CH 3 35B.2623 2-CN3-thiazol-4-yl-OCH
(CH
3 B .2623 2-CH-thiazol-4-yl-OCH(CH 3 B.2625 5-Br-thiazol-4-yl-OCH
(CH
3 B.2626 5-CN-thiazol-4-yl-OCH(CH 3 40B.2627 5-CN3-thiazol-4-yl-OCH
(CH
3 B. 2627 5-hiao-hao5-yl-OCH(CH 3 B .2628 thiaz-5-yal-OCH (CH(C 3 B. 2629 4-Br-thiazol-5-yl-OCH(CH 3 B.2631 4-Cl-thiazol-5-yl-OCH(CH 3 B. 2632 4-CH 3 -thiazol-5-yl-OCH
(CH
3 0050/ 46043 273 N~o. R 3 B-2633 2-Br-thiazol-5-yl-OCH(CH 3 B.2634 2-Cl-thiazol-5-yl-OCH(CH 3 B. 2635 2-CI'-thiazol-5-yl--OCH (CH 3 B.2636 2-CH 3 -thiazol-5-yl-OCH(CH 3 B.2637 isothiazol-3-yl-OCH(CH 3 B. 2638 4-Br-isothiazol-3-yl-OCH(CH 3 B. 2639 4-C 1-isothiazol-3-yl-OCH (CH 3 106 04 C s t ia o l O H C 3 B.2641 4-CH3-isothiazol-3-yl-OCH(CH 3 B.2642 4-CH-isothiazol-3-yl-OCH
(CE
3 B.2 642 5-Br-isothiazol-3-yl-OCH
(CH
3 B. 2643 5-C1-isothiazol-3-yl-OCH(CH 3 B .2644 5-CN3-isothiazol-3-yl-OCH(CH 3 B. 2645 5--isothiazol- 3yl-O CE(CH 3 B.2647 3-isothiazol-4-yl-OCH
CE
3 20B.2647 3-Br-isothiazol-4-yl-OCH
(CE
3 2648 3-C1-isothiazol-4-yl-OCH(CH 3 B .2649 3-CN3-isothiazol-4-yl-OCH
(C
3 B.2 650 3-CE-isothiazol-4-yl-OCH(CH 3 B.2651 5-Br-isothiazol-4-yl-OCH (CE 3 25B.2652 5-CN-isothiazol-4-yl-OCH(CH 3 B. 2653 5-CH3-isothiazo-4-y-OCH(CH 3 B. 2654 35-CH 3 -isothiazol-4-yl-OC
H(CH
3 B.2655 3,5-(hia) 2 -sylOthazH(C4ylHC3c) B.2656 3-isothiazol-5-yl-OCH( CH3) 3068 3C-stiao--lOHC3 B .2657 3-Br-isothiazol-5-yl-OCE
(CH
3 B.2660 3-CH3-isothiazol-5-yl-OC(CH 3 35B.2661 3-CN-isothiazol-5-yl-OCE
(CE
3 B. 2660 3-CH-isothiazol-5-yl-OCH(CH 3 B.2661 4-Br-isothiazol-5-yl-OCE
(CE
3 B. 2662 4-C13-isothiazol-5-yl-OCH
(CH
3 40B.2663 4-Ciothiazl-5-ylCH3 (E 3 B .2664 4-CH-isiazol--yl-OC(CH 3 40B.2665 ImBizol-2 l-CFI -OCH(CH) B.2666 1-C1-imidazol-2-yl-OC
CH
3 45B.2669 1-CH 3 -imidazol-2-yl-OCE (CE 3 456 04 C m d zo l O H C 3 B.2 670 4-Cr-imidazol-2-yl-OCH(CH 3 0050/46043 274 No. R B .2672 4-CN-imidazol-2-yl-OCH
(CH
3 B. 2673 4-CH 3 -imidazol-2-yl-OCH(CH 3 B.2674 1-CH 3 5-C1-imidazol-2-yl-OCH(CH 3 B.2675 l, 4
-(CH
3 2 -imidazol-2-Yl-OCH(CH 3 B.2676 l,5-(CH3) 2 -imidazol-2-yl-OCH(CH 3 B .2677 imidazol-4-yl-OCH
(CE
3 B.2678 2-C1-imidazol-4-yl-OCH(CH 3 106 92 B m d zo l O H C 3 B .2679 2-Br-imidazol-4-yl-OCH
(CE
3 B.2681 2-CH3-imidazol-4-yl-OCH(C 3 B.2682 1-CH3-imidazol-4-yl-QCH
(CH
3 is B.2683 2-CH-imidazol-4-yl-OCH
(CH
3 B .2683 5-C 1-imidazol-4-yl-OCH
(CE
3 B.2685 5-B-iLmi'dazo'L-4-yl-OCH
(CE
3 B. 2685 5-CN3-imidazo-4-yl-OCH
(C
3 B.2687 1-CE 3 5-Cl-imidazol-4-yl-OCH(CH 3 B.2688 l,2-(CH 3 2 -imidazol-4-yl-OCH(CH 3 B.2689 1, 5- (CE 3 2 -imidazol-4-yl-OCH
(CE
3 B.2 690 pyrazol-3-yl-OCH(CH 3 B.2691 5-Br-pyrazol-3-yl-OCE(CH 3 B.2692 5-C1-pyrazol-3-yl-OCH(CH 3 B.2693 5-CN-pyrazol-3-yl-OCH(CH 3 B.2694 5-CH 3 -pyrazol-3-yl-OCE(CH 3 B.2 695 1-C6H 5 -pyrazol-3-yl-OCH
(CH
3 B. 2696 4-Br-pyrazol-3-yl-OCE(CE 3 B.2697 4-Cl-pyrazol-3-yl-OCH(CH 3 B.2698 4-CN-pyrazol-3-yl-OCH(CH 3 B. 2699 4-CH 3 -pyrazol-3-yl-OCH
(CE
3 B.2700 1-CH3-pyrazol-3-yl-OCH(CH 3 B.2701 1, 4- (CH3) 2-pyrazol-3-y1-OCE
(CH
3 B.2702 1,5-(CH3)2-pyrazol-3-yl-OCH(CH 3 B.2703 1-CE 3 4-C-pyrazol-3-yl-OCH(CH 3 B.2704 1-CE 3 5-C-pyrazol-3-yl-OCH(CH 3 B. 2705 pyrazol-4-yl-OCH(CH 3 B .2706 3-Br-pyrazol-4-yl-OCE
(CE
3 B.2707 3-C1-pyrazol-4-yl-OCH(CH 3 B. 2708 3-CN-pyrazol-4-yl-OCH(CH 3 457 93 C 3 p r zo l O H C 3 B. 2710
-CH
3 -pyrazol-4-yl-OCH
(CE
3 0050/46043 275 No. R 3 B.2711 1,5-(CH3)2-pyrazol-4-yl-OCH(CH 3 B.2712 l,3-(CH3)2-pyrazol-4-yl-OCH(CH 3 B.2713 1-OH 3 3-Cl-pyrazol-4-yl-OCH(CH 3 B.2714 1-OH 3 5-Cl-pyrazol-4-yl-OCH(CH 3 B .2715 pyrazol-5-yl-OCH(
OH
3 B.2716 3-Br-pyrazol-5-yl-OCH
(CH
3 B.2717 3-Cl-pyrazol-5-yl-OCH(CH 3 1 07 83 C -p r z l 5 y l O H C 3 B.2719 3-CN3-pyrazol-5-yl-CH(CH 3 B .2719 3-CH 3 -pyrazol-5-yl-OCH
(OH
3 B .2720 1-0H-pyrazol-5-yl-OCH
(OH
3 B.2722 4-Br-pyrazol-5-yl-OCH(CH 3 15B.2723 4-C1-pyrazoi-5-yl-OCH(CH 3 B.2724 4-ON- pyrazol-5-yl-OCH(H 3 B .2724 4-C 3 -pyrazl--yr l-OOH(-CH(C 3 B.2726 1,4-(CH3)2--pyrazol-5-yl-OCH(CH 3 20B.2726 1-0H3) 2 -C-pyrazol-5-yl-OH(H 3 B.2728 1-OH 3 3-C1-pyrazol-5-yl-OCH(CH 3 B.2729 1-O 3 4-ol-azol-5-ylOH(CH 3 B.2739 2C1,3,4-oxadiazol-5-yl- OCH(0H 3 25B.2731 2-CH3-1,3,4-oxadiazol-5-yl-OCH(CH 3 B.2732 2-C3-1,3,4-oxadiazol-5-yl-OH(CH 3 B.2733 2-CH-1,3,4-oxadiazol-5-yl-OCH(H 3 B. 2733 2-Cl-i, 213,44-xad aol-5-l-CHl-CH 3 H3 B.2734 2 -OH0H3- 1,3,4zo-oxadiaOC -5yl-CH3H 3 30B.2736 5C1,3,4-oxadiazol-2-yCH
CH(C
B.2737 5-CH 3 4-oxadiazol-2-yl-OCH(CH 3 B.2738 5-CH3-1,3,4-oxadiazol-2-yl-OCH(H 3 B.2739 5-CH-1,3,4-oxadiazol-2-yl-OCH(CH 3 35B.2740 5-C1()-1,3,4-oxadiazol-2-yl-OCH(CH 3 B.2741 5-C6H(C3-1,3,4-oxadiazol-2-yl-OH(H 3 B.2742 5-C6H-1,3,4z-oaial-2-yl-oC (0H 3 B.2743 5C1,2,4-oxadiazol-3-yl-OCH(C 40B.2744 5-CH 3 4-oxadiazol-3-yl-OCH(CH 3 B.2745 5-C3-1,2,4-oxadiazol-3-yl-OCH(H 3 B.2746 5-00H-1,2,4-oxadiazol-3-yl-OCH(H 3 B.2747 5-Cl()-1,2,4-oxadiazol-3-yl-OCH(CH 3 B.2748 1,2,4-triazol-3-yl-OCH(CH 3 B.2749 1-CH3-1,2,4-triazol-3-yl-OCH(CH 3 0050/46043 276 No.
R
B.2750 5-CH3-1,2,4-triazo2l-3-yl-OCH(CH 3 B.2751 5-CF3-1,2,4-triazol-3-yl-OCH(CH 3 B.2752 5-OCH3-1,2,4-triazol-3-yl-OCH(CH 3 B.2753 5-Cl-1,2,4-triazol-3-yl-OCH(CH 3 B.2754 5-CH(CH3)2-1,2,4-triazol-3-yl-OCH(CH 3 B.2755 l-C6H5-1,2,4-triazol-3-yl-OCH(CH 3 B.2756 1,3,4-thiadiazol-5-yl-OCH(CH 3 1 0B 7 72 C 3 1 3 4 t i d a o 5 y l O H C 3 B.2758 2-CH3-1,3,4-thiadiazol-5-yl-OCH(CH 3 B.2759 2-C 3 4-thiadiazol-5-yl-OCH(CH 3 B.2760 2 -CHC3-1,3, 4-thiadizol-5-ylOCH
(CH
3 B.2761 2-CH 2
OH
3 13,4-thiadiazol--5-yl-OCH(CH 3 B.2762 2-CH()-1,3,4-thiadiazol-5-yl-OCH(CH 3 .2762 13, 2CH(h'a)2-1,3, -idaoC-5yl-CH3H B.*2763 1,C3 -thiad-iaodio-2CH CH(C 3 B.2765 5-CH 3 3, 4-thiadiazol-2-yl-OCH(CH 3 20B.2766 5-C3-1,3,4-thiadiazol-2-yl-OCH(CH 3 B.2767 5-CH-1,3,4-thiadiazol-2-yl-OCH(CH 3 B.2768 5-C1-1H3,42-1,h3iadtial-2-l-2cH(CH 3 B.2769 5-C6H(C3-1,3,4-thiadiazol-2-yl-OCH(CH 3 B.2769 5-C 6
H
5 34-iadiazo-l-2-ylCH cH 3 B.2771 5C1,2,4-thiadiazol-3-yl-OCH(CH 3 B.2772 5-CH 3 4-thiadiazol-3-yl-OCH(CH 3 B.2773 5-C 3 2,4-tiadiazol-3-yl-OCH(CH 3 B.2774 5-CH-1,2 ,4-thiadiazol-3-yl-OCH(CH 3 30B.2775 5-CH -1,24-1,h2iadtial-3-l-3CH(0H 3 B.2776 5-CH(CH 3 2 -1,2,4-Hiaiaol3ylOc3c 3 B. 2776 pyrrl-2yl-OCHl-CH(C 3 B.2778 4-C1-pyrrol-2-yl-OCH(CH 3 B.2778 4-Br3-pyrrol-2-yl-OCH
(CH
3 B.2780 4-C6H5-pyrrol-2-yl-OCH(CH 3 B. 2781 benzimidazol-2-yl-OCH(CH 3 B.2782 quinolin-2-yl-OCH(CH 3 B.2783
CH=CH
2 B.2784
C(CH
3
)=CH
2 B.2785 CH=CH(CH 3
(E)
B.2786 CH=CH(CH 3
(Z)
4577
CHC=H
B.2788
C(H
2 CH3)=CH T.78 CCHC 3
=H
0050/ 46043 277 No. R B.2789 C(CH 3
)=CH(CH
3
(E)
B.2790
C(CH
3
)=CH(CH
3
(Z)
B.2791 C(CH 3
)=C(CH
3 2 B.2792
CH(CH
3
)-CH=CH
2 B.2793
CH=C(CH
3 2 B.2794
CH
2
-C(CH
3
)=CH
2 B.2795 CH(CH 3
)-CH
2
-CH=CH
2 B.2796
CH
2
-CH(CH
3
)-CH=CH
2 B.2797
CH
2
CCL=CH
2 B.2798 CH 2 CH=CHC. (E) B.2799
CH
2 CH=CHC1
(Z)
B.2800
CH
2 CC1=CHCl
(E)
B.2801 CH 2 CC1=CHC1 (Z) B.2802
CH
2 CH=CC1 2 B.2803
CH
2 CC1=CC1 2 B.2804 CH 2 CBr=CH 2 B.2805 CH 2 CH=CHBr (E) B.2806 CH 2 CH=CHBr (Z) B.2807 CH 2 CBr=CHBr (E) B.2808 CH 2 CBr=CHBr (Z) B.2809 CHgCH=CBrg B .2810
CH
2 CBr=CBr 2 B.2811 CH 2
CH=CHCH
3
(E)
B.2812 CH 2
CH=CHCH
3
(Z)
B.2813 CH 2
C(CH
3
)=CHCH
3
(E)
B.2814
CH
2
C(CH
3
)=CHCH
3
(Z)
B.2815
CH
2
CH=C(CH
3 2 B .2816
CH
2
CH
2
CH=CH
2 B.2817 CH 2 CC1=CHCH 3
(E)
B.2818
CH
2 CC1=CHCH 3
(Z)
B.2819 CH 2 CH=CC1CH 3
(E)
B.2820
CH
2 CH=CC1CH 3
(Z)
B.2821 CH 2
C(CH
3
)=C(CH
3 2 B.2822 CH 2 CBr=CHCH 3
(E)
B.2823 CH 2 CBr=CHCH 3
(Z)
B.2824 CH 2 CH=CBrCH 3
(E)
B.2825 CH 2 CH=CBrCH 3
(Z)
4586 C2H=HHC E B.2827 ICH 2
CH=CHCH
2 C. (E) 0050/46043 278 No. R 3 B.2828 CH 2 CH= CHCH 2
CH
3
(E)
B.2829
CH
2
CH=CHCH
2
CH
3
(Z)
B.2830 CH 2
CH=CHCH
2 Br (E) B.2831 CH 2
CH=CHCH
2 Br (Z) B.2832 CH 2 CC1=CC1CH 2 Cl (E) B.2833
CH
2 CC1=CClCH 2 C1 (Z) B.2834
CH
2
CF=CH
2 1085 C2C=H E B.2836 CH 2 CH=CHF (E) B.2837
CH
2
CH=CF
2 B.2838 CH 2 CF=CHF (E) B.2839
CH
2 CF=CHF (Z) B.2840
CH(CH
3
)CH=CH
2 B.2841 'CH(CH 3
)CCI=CH
2 B.2842 CH(CH 3 )CH=CHC1 (E) B.2843 CH(CH 3 )CH=CHC1 (Z) B.2844 CH(CH 3 )CC1=CHC1 (E) B.2845 CH(CH 3 )CC1=CHC1 (Z) B.2846
CH(CH
3 )CH=CC1 2 B.2847 CH(CH 3 )CC1=CC1 2 B.2848
CH(CH
3 )CBr=CH 2 B.2849 CH(CH 3 )CH=CHBr (E) B.2850 CH(CH 3 )CH=CHBr (Z) B.2851
CH(CH
3 )CBr=CHBr (E) 30B.2852
CH(CH
3 )CBr=CHBr (Z) B.2853
CH(CH
3 )CH=CBr 2 B.2854
CH(CH
3 )CBr=CBr 2 B.2855
CH(CH
3
)C(CH
3
)=CH
2 B.2856 CH(CH 3
)CH=CHCH
3
(E)
B.2857
CH(CH
3
)CH=CHCH
3
(Z)
B.2858 CH(CH 3
)C(CH
3
)=CHCH
3
(E)
B.2859
CH(CH
3
)C(CH
3
)=CHCH
3
(Z)
B.2860 CH(CH 3
)CH=C(CH
3 2 B.2861 CH(CH 3 )CC1=CHCH 3
(E)
B.2862
CH(CH
3 )CC1=CHCH 3
(Z)
B.2863 CH(CH 3 )CH=CC1CH 3
(E)
B.2864 CH(CH 3 )CH=CClCH 3
(Z)
4585 C(C3CrCHH E B.2866
CH(CH
3 )CBr=CHCH 3
(Z)
B.266 H(C 3 )Cr=CCH 3
(Z
I
0050 /46043 279 No.
R
B.2867 CH(CH 3 )CH=CBrCH 3
(E)
B.2868 CH(CH 3 )CH=CBrCH 3
(Z)
B.2869 CH(CH 3
)CH=CHCH
2 C1 (E) B.2870 CH(CH 3
)CH=CHCH
2 C1 (Z) B.2871 CH(CH 3
)CH=CHCH
2
CH
3
(E)
B.2872 CH(CH 3
)CH=CHCH
2
CH
3
(Z)
B.2873
CH(CH
3
)CH=CHCH
2 Br (E) B.2874 CH(CH 3
)CH=CHCH
2 Br (Z) B.2875 CH(CH 3 )CC1=CC1CH 2 Cl (E) B.2876 CH(CH 3 )CC1=CC1CH 2 Cl (Z) B.2877 CH(CH 3
)CF=CH
2 B.2878 CH(CH 3 )CH=CHF (E) B.2879 CH(CH 3 )CH=CHF (Z) B.2880 CH(CH 3
)CH=CF
2 B.2881 CH(CH 3 )CF=CHF (E) B.2882 CH(CH 3 )CF=CHF (Z) B. 2883 CH 2 CHClCH=CH 2 B.2884 CH 2
CH
2
CH=C(CH
3 2 B.2885 CH 2
CH
2
C(CH
3
)=CHCH
3
(E)
B.2886 CH 2
CH
2
C(CH
3
)=CHCH
3
(Z)
B.2887 2-F-C 6
H
4
-CH=CH
B.2888 3-F-C 6
H
4
-CH=CH
B.2889 4-F-C 6
H
4
-CH=CH
B .2890 2, 3-F 2
-C
6
H
3
-CH=CH
B.2891 2,4-F 2
-C
6
H
3
-CH=CH
B.2892 2,5-F 2
-C
6
H
3
-CH=CH
B. 2893 2, 6-F 2
-C
6
H
3
-CH=CH
B.2894 3,4-F 2
-C
6
H
3
-CH=CH
B.2895 3,5-F 2
-C
6
H
3
-CH=CH
B.2896 2-Cl-C 6
H
4
-CH=CH
B.2897 3-C1-C 6
H
4
-CH=CH
B. 2898 4-Cl-C 6
H
4
-CH=CH
B.2899 2,3-Cl 2
-C
6
H
3
-CH=CH
B.2900 2,4-Cl 2
-C
6
H
3
-CH=CH
B.2901 2, 5-C1 2
-C
6
H
3
-CH=CH
B .2902 2, 6-Cl 2
-C
6
H
3
-CH=CH
B.2903 3,4-Cl 2
-C
6
H
3
-CH=CH
B.2904 3, 5-Cl 2
-C
6
H
3
-CH=CH
B.2 905 12,3, 4-C1 3
-C
6
H
2
-CH=CH
0I
X,
0050/46043 280 No. R 3 B. 2906 2,3, 5-C1 3
-C
6
H
2
-CH=CH
B. 2907 2,3, 6-Cl 3
-C
6
H
2
-CH=CH
B. 2908 2,4, 5-C1 3
-C
6
H
2
-CH=CH
B.2909 2,4,6-C1 3
-C
6
H
2
CH=CH
B.2910 3,4,5-Cl 3
-C
6
H
2
-CH=CH
B. 2911 2-Br-C 6
H
4
-CH=CH
B. 2912 3-Br-C 6
H
4
-CH=CH
B.2913 4-Br-C 6
H
4
-CH=CH
B. 2914 2, 3-Br 2
-C
6
H
3
-CH=CH
B. 2915 2, 4-Br 2
-C
6
H
3
-CH=CH
B.2916 2,5-Br 2
-C
6
H
3
-CH=CH
B.2917 2, 6-Br 2
-C
6
H
3
-CH=CH
B.2918 3, 4-Br 2
-C
6
H
3
-CH=CH
B 919 3, 5-Br 2
-C
6
H
3
-CH=CH
B.2920 2-F, 3-Cl-C 6
H
3
-CH=CH
B.2921 2-F, 4-Cl-C 6
H
3
-CH=CH
B.2922 2-F, 5-Cl-C 6
H
3
-CH=CH
B.2923 2-F, 3-Br-C 6
H
3
-CH=CH
B.2924 2-F, 4-Br-C 6
H
3
-CH=CH
B.2925 2-F, 5-Br-C 6
H
3
-CH=CH
B.2926 2-Cl, 3-F-C 6
H
3
-CH=CH
B.2927 2-Cl, 4-F-C 6
H
3
-CH=CH
B.2928 2-Cl, 5-F-C 6
H
3
-CH=CH
B.2929 2-Cl, 3-Br-C 6
H
3
-CH=CH
B.2930 2-Cl, 4-Br-C 6
H
3
-CH=CH
B.2931 2-Cl, 5-Br-C 6
H
3
-CH=CH
B.2932 2-Br, 3-F-C 6
H
3
-CH=CH
B.2933 2-Br, 4-F-C 6
H
3
-CH=CH
B.2934 2-Br, 5-F-C 6
H
3
-CH=CH
B.2935 2-Br, 3-Cl-C 6
H
3
-CH=CH
B.2936 2-Br, 4-Cl-t 6
H
3
-CH=CH
B.2937 2-Br, 5-Cl-C 6
H
3
-CH=CH
B.2938 4-Cl, 3,5-Br 2
-C
6
H
2
-CH=CH
B.2939 2-CN-C 6
H
4
-CH=CH
B. 2940 3-CN-C 6
H
4
-CH=CH
B. 2941 4-CN-C 6
H
4
-CH=CH
B. 2942 2-N0 2
-C
6
H
4
-CH=CH
B.2943 3-N0 2
-C
6
H
4
-CH=CH
B. 2944 4-N0 2
-C
6
H
4
-CH=CH
0050/46043 281 No.
R
B.2945 2-CH 3
-C
6
H
4
-CH=CH
B. 2946 3-CH 3
-C
6
H
4
-CH=CH
B.2947 4-CH 3
-C
6
H
4
-CH=CH
B.2948 2,3-(CH 3 2
-C
6
H
3
-CH=CH
B.2949 2,4-(CH 3 2
-C
6
H
3
-CH=CH
B.2950 2,5- (CH 3 2
-C
6
H
3
-CH=CH
B.2951 2,6- (CH 3 2
-C
6
H
3 -CzH=CH B.2952 3,4-(CH 3 2
-C
6
H
3
-CH=CH
B.2953 3,5- (CH 3 2
-C
6
H
3
-CH=CH
B .2954 2-CH 2
CH
3
-C
6
H
4
-CH=CH
B. 2955 3-CH 2
CH
3
-C
6
H
4
-CH=CH
is B.2956 4-CH 2
CH
3
-C
6
H
4
-CH=CH
B.2957 2-CH(CH 3 2
-C
6
H
4
-CH=CH
B.2958 3==cH (OH 3 2
-C
6
H
4
-CH=CH
B.2959 4-CH (CH 3 2
-C
6
H
4
-CH=CH
B.2960 3-C(CH 3 3
-C
6
H
4
-CH=CH
B.2961 4-C(CH 3 3
-C
6
H
4
-CH=CH
B.2962 2-C 6
H
5
-C
6
H
4
-CH=CH
B .2963 3-C 6
H
5
-C
6
H
4
-CH=CH
B.2964 4-C 6
H
5
-C
6
H
4
-CH=CH
B .2965 2-OCH 3
-C
6
H
4
-CH=CH
B .2966 3-OCH 3
-C
6
H
4
-CH=CH
B. 2967 4-QCH 3
-C
6
H
4
-CH=CH
B.2968 2, 3- (OCH 3 2
-C
6
H
3
-CH=CH
B.2969 2,4-(OCH 3 2
-C
6
H
3
-CH=CH
B.2970 2,5-(OCH 3 2
-C
6
H
3
-CH=CH
B.2971 2,6-(OCH 3 2
-C
6
H
3
-CH=CH
B.2972 3, 4- (OCH 3 2
-C
6
H
3
-CH=CH
B.2973 3, 5- (OCH 3 2
-C
6
H
3
-CH=CH
B.2974 3,4,5-(00H 3 3
-C
6
H
2
-CH=CH
B.2 975 2-OCH 2
CH
3
-C
6
H
4
-CH=CH
B.2976 3-OCH 2
CH
3
-C
6
H
4
-CH=CH
B.2977 4-OCH 2
CH
3
-C
6
H
4
-CH=CH
B.2978 2-O(CH 2 )2CH 3
-C
6
H
4
-CH=CH
B.2979 3-0(CH 2 2
CH
3
-C
6
H
4
-CH=CH
B.2980 4-0 (OH 2 2
CH
3
-C
6
H
4
-CH=CH
B.2981 2-OCH (CH 3 2
-C
6
H
4
-CH=CH
4592 3OC(H)-CH-HC B.2983 3-OCH (CH 3 2
-C
6
H
4
-CH=CH
0050/46043 ____282 No. R B.2984 3-OC(CH 3 3
-C
6
H
4
-CH=CH
B.2 985 4-OC(CH 3 )3-C6H 4
-CH=CH
B.2986 2-OCH 2
CH=CH
2
-C
6
H
4
-CH=CH
B. 2987 3-OCH 2
CH=CH
2
-C
6
H
4
-CH=CH
B. 2988 4-OCH 2
CH=CH
2
-C
6
H
4
-CH=CH
B. 2989 2-CF 3
-C
6
H
4
-CH=CH
B.2990 3-CF 3
-C
6
H
4
-CH=CH
B.2991 4-CF 3
-C
6
H
4
-CH=CH
B.2 992 2
-CO
2
CH
3
-C
6
H
4
-CH=CH
B.2 993 3 -CO2CH 3
-C
6
H
4
-CH=CH
B.2 994 4 -C02CH3-C 6
H
4
-CH=CH
B.2995 2 -CO2CH2CH 3
-C
6
H
4
-CH=CH
B. 2996 3-CO2CH2CH3-C 6
H
4
-CH=CH
B- 2997 4-CO2CH2CH 3
-C
6
H
4
-CH=CH
B. 2998 2-CONH 2
-C
6
H
4
-CH=CH
B.2999 3-CONH 2
-C
6
H
4
-CH=CH
B. 3000 4
-CONH
2
-C
6
H
4
-CH=-CH
B.3001 2
-CON(CH
3 2
-C
6
H
4
-CH=CH
B.3002 3
-CON(CH
3 2
-C
6
H
4
-CH=CH
B.3003 4
-CON(CH
3 2
-C
6
H
4
-CH=CH
B. 3004 2
-CONHCH
3
-C
6
H
4
-CH=CH
B. 3005 3
-CONHCH
3
-C
6
H
4
-CH=CH
B.3006 4-CONHCH 3
-C
6
H
4
CH=CH
B. 3007 2-NH 2
-C
6
H
4
-CH=CH
B.08 3N2CH-HC B. 3008 3-NH 2
-C
6
H
4
-CH=CH
B. 3010
-N(H
2
-C
6
H
4
-CH=CH
B.3011 3-N (CH3) 2
-C
6
H
4
-CH=CH
B.3012 4-N(CH3) 2
-C
6
H
4
-CH=CH
B.3013 4-N(CH3)-C 6
H
4
-CH=CH
B. 3013 2-NHCH 3
-C
6
H
4
-CH=CH
B.3014 3-NHCH 3
-C
6
H
4
-CH=CH
B. 3015 4-CNH2-C 6
H
4
-CH=CH
B.3017 2-CSNH 2
-C
6
H
4
-CH=CH
B. 3017 3-CSNH 2
-C
6
H
4
-CH=CH
B. 3018 2-SCH-C 6
H
4
-CH=CH
B.3020 2-SCH 3
-C
6
H
4
-CH=CH
B.3021 3-SCH 3
-C
6
H
4
-CH=CH
B.3 022 2-SOCH 3
-C
6
H
4
-CH=CH
0050/46043 283 No. R B.3023 3-SOCH 3
-C
6
H
4
-CH-=CH
B. 3024 4-SOCH 3
-C
6
H
4
-CH=CH
B.3025 2-SO 2
CH
3
-C
6
H
4
-CH=CH
B.3026 3-SO2CH 3
-C
6
H
4
-CH=CH
B.3027 4-SO 2
CH
3
-C
6
H
4
-CH=CH
B. 3028 2-OCF 3
-C
6
H
4
-CH=CH
B. 3029 3-OCF 3
-C
6
H
4
-CH=CH
1000 4OF3CH-HC B. 3030 4-OCF-C 6
H
4
-CH=CH
B.3032 2-OCHF 2
-C
6
H
4
-CH=CH
B.3033 3-OCHF 2
-C
6
H
4
-CH=CH
B.3034 3-CF 3 4-QCF 3
-C
6
H
3
-CH=CH
B. 3035 2-CH 2
CH
2
F-C
6
H
4
-CH=CH
B.3036 3-tCH2CH 2
F-C
6
H
4
-CH=CH
B.3037 4-CH 2
CH
2
F-C
6
H
4
-CH=CH
B.3038 2-CH 2
CF
3
-C
6
H
4
-CH=CH
B.3039 3-CH 2
CF
3
-C
6
H
4
-CH=CH
B.3040 4-CH 2
CF
3
-C
6
H
4
-CH=CH
B. 3041 2-CF 2
CHF
2
-C
6
H
4
-CH=CH
B.3042 3-CF 2
CHF
2
-C
6 11 4
-CH=CH
B. 3043 4-CF 2
CHF
2
-C
6
H
4
-CH=CH
B.3044 2-CHF 2
-C
6
H
4
-CH=CH
B.3045 3-CHF 2
-C
6
H
4
-CH=CH
B.3046 4-CHF 2
-C
6
H
4
-CH=CH
B.3047 naphthalen-1-yl-CH=CH B. 3048 naphthalen-2-yl-CH=CH B. 3049 pyridin-2-yl-CH=CH B. 3050 pyridin-3-yl-CH=CH B.3051 pyridin-4-yl-CH=CH B.3052 5-CH 3 -pyridin-2-yl-CH=CH B. 3053 6-CH 3 -pyridin-2-yl-CH=CH B. 3054 5-CH 3 -pyridin-3-yl-CH=CH B.3055 6-CH 3 -pyridin-3-yl-CH=CH B.3056 5-QCH 3 -pyridin-2-yl-CH=CH B. 3057 6-OCH 3 -pyridin-2-yl-CH=CH B. 3058 5-OCH3-pyridin-3-yl-CH=CH B. 3059 6-OCH 3 -pyridin-3-yl-CH=CH 4500 4C-yidn2y-HC B.3061 4-C1-pyridin--2-yl-CH=CH 0050/46043 284 No. R 3 B. 3062 6 -Cl-pyridin-2-yl-CH=CH B. 3063 2 -Cl-pyridin-3-yl-CH=CH B.3064 5-Cl-pyridin-3-yl-CH=CH B. 3065 6-Cl-pyridin-3-yl-CH=CH B. 3066 2 -Cl-pyridin-4-yl-CH=CH B. 3067 3, S-Cl2-pyridin-2-yl-CH=CH B. 3068 pyrimidin-2-yl-CH=CH B36 -lprmdn2y-HC B. 3069 5-Cl-pyrimidin-2-yl-CH=CH B. 3070 4-Cl3-pyrimidin-2-yl-CH=CH B. 3071 5-CH3-pyrimidin-2-yl-CH=CH B. 3072 4-OCH3-pyrimidin-2-yl-CH=CH B. 3073 5-OCH3-pyrimidin-2-yl-CH=CH B..30745 py-OCH3n-pimdi-2-ylCH B. 3075 2-pyrimidin-4-yl-CH=CH B. 3076 6-Cl-pyrimidin-4-yl-CH=CH 3077 26-Cl-pyrimidin-4-yl-CH=CH B. 3078 2, -C1-pyrimidin-4-yl-CH=CH B.3080 2-CH3-pyrimidin-4-yl-CH=CH B.3081 2-OCH3-pyrimidin-4-yl-CH=CH 3081 6-OCH 3 -pyrimidin-4-yl-CH=CH B. 3082 2-QCCH3-pyrimidin-4-yl-CH=CH B.3 083 6-OCH2CH3-pyrimidin-4-yl-CH=CH B. 3084 pyOCH2CH3-p-yrimdi-4-=-HC B.3 085 3007 2C3-yiii-5y-HC B. 3086 B.3 087 B. 3088 B.3091 4-furan-2-yl-CH=
CH
35B.3092 4-Cr-furan-2-yl-CH=CH B. 3091 4-CH3-furan-2-yl-CH=CH 3092 4-CN-furan-2-yl-CH=CH B. 3093 4-CH-furan-2-yl-CH=CH 40B.3096 5-Br-furan-2-yl-CH=CH B. 3095 5-CH3-furan-2-yl-CH=CH 3096 B. 3097 5-CH-furan-2-yl-CH=CH B.31008 frn3y-HC B. 0 -C1-furan-3-yl-CH=CH 0050/46043 285 No.
R
B.3 101 5-CN-furan-3-yl-CH=CH B. 3102 5-CH 3 -furan-3-yl-CH=CH B.3 103 thien-2-yl-CH=CH B. 3104 4-Br-thien-2-yl-CH=CH B. 3105 4-Cl-thien-2-yl-CH=CH B. 3106 4-CN-thien-2-yl-CH=CH B. 3107 4-CH 3 -thien-2-yl-CH=CH 1018 5B-hin2y-HC B. 3108 5-Cr-thien-2-yl-CH=CH B.3110 5-C1-thien-2-yl-CH=CH B. 3110 5-CN3-thien-2-yl-CH=CH B. 3111 5-CHn 3 -hel--yCH~c B.3113 5-thien-3-yl-CH=CH B. 311 IArtie--l-HC 11 5-Cl-thien-3-yl-CH=CH B. 3115 5-CN-thien-3-yl-CH=CH B.3116 5-CH3-thien-3-yl-CH=CH B.3 117 oxazol-2-yl-CH=CH B. 3118 4-Br-oxazol-2-yl-CH=CH B. 3119 4-Cl-oxazol-2-yl-CH=CH B.3120 4-CN-oxazol-2-y.-CH=CH B. 3121 4-CH3-oxazol-2-yl-CH=CH B.3 122 5-Br-oxazol-2-yl-CH=CH B. 3123 5-C1-oxazol-2-yl-CH=CH B. 3124 5-CN-oxazol-2-yl-CH=CH B.3125 5-CH 3 -oxazol-2-yl-CH=CH B. 3126 oxazol-4-yl-CH=CH B. 3127 2-Br-oxazol-4-yl-CH=CH B. 3128 2-C1-oxazol-4-yl-CH=CH B.3129 2-CN-oxazol-4-yl-CH=CH B. 3130 2-CH 3 -oxazol-4-yl-CH=CH B. 3131 2-C6H 5 -oxazol-4-yl-CH=CH B. 3132 5-Br-oxazol-4-yl-CH=CH B.3133 5-Cl-oxazol-4-yl-CH=CH B.3 134 5-CN-oxazol-4-yl-CH=CH B.3 135 5-CH3-oxazol-4-yl-CH=CH B.3 136 B.3 137 4518 B.3 138 4-C1-oxazol-5-yl-CH=CH 0050/46043 286 No. R 3 B .3140 4-CH 3 B .3141 B.3142 2-C1-oxazol-5-yl-CH=CH B.3 143 B.3 144 2-CH 3 B. 3145 isoxazol-3-yl-CH=CH B. 3146 4-Br-isoxazol-3-yl-CH=CH 1017 4Clioao-3y-HC B. 3147 4-CN-isoxazol-3-yl-CH=CH B.3 148 4-CN3-isoxazol-3-yl-CH=CH B.3 149 4-CH-isoxazol-3-yl-CH=CH B. 3150 5-Br-isoxazol-3-yl-CH=CH B.3152 5-C l-isoxazol-3-yl-CH=CH B .3 152 5-CN3-isoxazol-3-yl-CH=CH B. 3153 5-CH 3 z-xzo-yl-CH=CH B. 3154 3-isoxazol-4-yl-CH=CH 20B.3 155 3-Cr-isoxazol-4-yl-CH=CH B. 3156 3-CN-isoxazol-4-yl-CH=CH B. 3157 3-CN3-isoxazol-4-yl-CH=CH B.3158 3-CH 3 -isoxazol-4-yl-CH=CH B.3 159 5-Br-isoxazol-4-yl-CH=CH B.3 160 5-CN-isoxazol-4-yl-CH=CH B. 3161 5-CN3-isoxazol-4-yl-CH=CH B .3162 35-CH 3 -isoxazol-4-yl-CH=CH B.3 1634,-
C
3 isxao-isoxzol--yl-H= 30B.3165 B.3 165 B. 3166 B. 3167 3-CN3-isoxazol-5-yl-CH=CH 3168 3-C6H5-isoxazol-5-yl-CH=CH B.317 169 3-C 6
H
5 B. 3170 4-Cl, 3-C 6
H
5 B.3172 4-Br, 40B.3 172 B. 3173 B.3 174 4-CH3-isoxazol-5-yl-CH=CH B.3175 B.3 176 4-thiazol-2-yl-CH=CH B. 3178 4-Cl-thiazol-2-yl-CH=CH IT (c 0050/46043 287 No.
R
B.3 179 4-CN-thiazol-2-yl-CH=CH B. 3180 4-CH 3 -thiazol-2-yl-CH=CH B. 3181 5-Br-thiazol-2-yl-CH=CH B. 3182 5-Cl-thiazol-2-yl-CH=CH B. 3183 5-CN-thiazol-2-yl-CH=CH B.3 184 5-CH 3 -thiazol-2-yl-CH=CH B. 3185 thiazol-4-yl-CH=CH B. 3186 2-Br-thiazol-4-yl-CH=CH B. 31 8 7. 2-Cl-thiazol-4-yl-CH=CH B. 3188 2-CN-thiazol-4-yl-CH=CH B.3 189 2-CH 3 -thiazol-4-yl-CH=CH B. 3190 5-Br-thiazol-4-yl-CH=CH B. 3191 5-Cl-thiazol-4-yl-CH=CH B. 3192 5-CN-thiazol-4-yl-CH=CH B. 3193 5-CH 3 -thiazol-4-yl-CH=CH B. 3194 B. 3195 B. 3196 4-C1-thiazol-5-yl-CH=CH B. 3197 B. 3198 4-CH 3 B. 3199 B. 3200 B. 3201 B. 3202 2-CH 3 B. 3203 isothiazol-3-yl-CH=CH B. 3204 4-Br-isothiazol-3-yl-CH=CH B. 3205 4-Cl-isothiazol-3-yl-CH=CH B. 3206 4-CN-isothiazol-3-yl-CH=CH B. 3207 4-CH 3 -isothiazol-3-yl-CH=CH B.3208 5-Br-isothiazol-3-yl-CH=CH B. 3209 5-Cl-isothiazol-3-yl-CH=CH B. 3210 5-CN-isothiazol-3-yl-CH=CH B. 3211 5-CH 3 -isothiazol-3-yl-CH=CH B. 3212 isothiazol-4-yl-CH=CH B. 3213 3-Br-isothiazol-4-yl-CH=CH B.3214 3-C 1-isothiazol-4-yl-CH=CH B. 3215 3-CN-isothiazol-4-yl-CH=CH B. 3216 3-CH 3 -isothiazol-4-yl-CH=CH B. 3217 5-Br-isothiazol-4-yl-CH=CH 0050/46043 288 No.
R
B. 3218 5-C1-isothiazol-4-yl-CH=CH B.3219 5-CN-isothiazol-4-yl-CH=CH B. 3220 5-CH 3 -isothiazol-4-yl-CH=CH B.3221 3, 5-(CH 3 2 -isothiazol-4-yl-CH=CH B .3222 B.3223 B. 3224 3-C1-isothiazol-5-yl-CH=CH 1025 B. 3225 3-CN3-isothiazol-5-yl-CH=CH B. 3226 B. 3227 B. 3228 3229 4-CH3-isothiazol-5-yl-CH=CH B.3231 4-CH 3 zo-isthaoll-CH=C B. 3231 Imial-2-yazl-2H=CH=C B. 3232 1-C1-imidazol-2-yl-CH=CH 3233 I-Cr-imidazol-2-yl-CH=CH B.3235 I-C1H-imidazol-2-y-CH=CH B. 3235 4-CH-imidazol-2-yl-CH=CH B. 3236 4-C1-imidazol-2-yl-CH=CH 25B.3238 4-Cr-imidazol-2-yl-CH=CH B. 3238 4-CN3-imidazol-2-yl-CH=CH B. 3239 4-CH 3 -mdl-2-yazl-H=CH=C B. 3240 1,-CH 3 -C-imidazol-2-yl-CH=CH B.3242 1, 4-(CH 3 2 -imidazol-2-yl-CH=CH B.32423 1 5-(CH 3 )-imiazo-2-l-CCHc B. 3243 2-imidazol-4-yl-CH=CH B.3245 2-C1-imidazol-4-yl-CH=CH B. 3245 2-Br-imidazol-4-yl-CH=CH 3246 2-CN3-imidazol-4-yl-CH=CH B.3248 2-CH 3 -imidazol-4-yl-CH=CH B. 3248 2-CH-imidazol-4-yl-CH=CH B.3250 5-C1-imidazol-4-yl-CH=CH 3250 5-Cr-imidazol-4-yl-CH=CH B. 3251 5-CN3-imidazol-4-yl-CH=CH B.3253 5-CH3, -mdl-4-yazl-H=CH=C B. 3253 1,-CH 3 -C-imidazol-4-yl-CH=CH B.3255 1,5- (CH 3 2 -imidazol-4-yl-CH=CH B.-3256 lpyrazol-3-yl-CH=CH
VN
0050/46043 289 No.
R
B. 3257 5-Br-pyrazol-3-yl-CH=CH B .3258 5-Cl-pyrazol-3-yl-CH=CH B.3259 5-CN-pyrazol-3-yl-CH=CH B. 3260 5-CH 3 -pyrazol-3-yl-CH=CH B. 3261 1-C 6
H
5 -pyrazol-3-yl-CH=CH B .3262 4-Br-pyrazol-3-yl-CH=CH B. 3263 4-C1-pyrazol-3-yl-CH=CH 1024 4C-yazl3y-HC B.3264 4-CH3-pyrazol-3-yl-CH=CH B. 3265 4-CH 3 -pyrazol-3-yl-CH=CH B. 3266 1,-CH 3 pra- -yl-CH=lCH=C B.3268 1,5- (CH 3 2 -pyrazol-3-yl-CH=CH B.3269 1,-CH 3 2 -C-pyrazol-3-yl-CH=CH B. 3269 1-CH 3 4-C1-pyrazol-3-yl-CH=CH B.3271 -C 3 pyao--yrazl-3yl-HC B. 3271 3-pyrazol-4-yl-CH=CH B.3273 3-Cr-pyrazol-4-yl-CH=CH B.3274 3-CN-pyrazol-4-yl-CH=CH B.3275 3-CH3-pyrazol-4-yl-CH=CH B.3275 3-CH 3 -pyrazol-4-yl-CH=CH B. 3276 1, CH 3 -pyrazol-4-ylCH= B.3278 1, 5-(CH 3 2 -pyrazol-4-yl-CH=CH B.3279 1,-CH 3 2 pyrazol-4-yl-CH=CH B.3280 1-CH 3 3-C1-pyrazol-4-yl-CH=CH B.3280 py-CH 3 5-1-yazl--y-C=C B.3282 B .3282 B. 3283 3-C1-pyrazol-5-yl-CH=CH B.3284 3-CN3-pyrazol-5-yl-CH=CH B. 3285 3-CH 3 B .3286 B.3288 B.3288 40B.3290 4-CN3-pyrazol-5-yl-CH=CH B .3290 4-C 3 -C pyrazol-5-yl -CH=C B .3291 1,3- (CH 3 B.3292 1,-CH3)2-C-pyrazol-5-yl-CH=CH B. 3293 1-CH 3 3-C1-pyrazol-5-yl-CH=CH B .3295 1,3, "Y*4 0050/46043 290 No. R 3 B.3296 2-CH 3 3, B.3297 2-CF 3 -1,3,4-oxadiazol-5-yl-CH=CH B.3298 2-OCH 3 B.3299 2-Cl-i, 3,4-oxadiazol-5-yl-CH=CH B.3300 2-CH(CH 3 2 -l,3,4-oxadiazol-5-yl-CH=CH B.3301 1,3, 4-oxadiazol-2-yl-CH=CH B.3302 5-CH 3 -1 4-oxadiazol-2-yl-CH=CH B.33 5C3134oaizl2yCHC B.3304 5-C 3 3,4-oxadiazol-2-yl-CH=CH B.3305 5-CH-1, 3,4-oxadiazol-2-yl-CH=CH B.3306 5-Cl-i, 213, 4-xadaol-2-l-CH=lCH=C B.3307 5-C6H(CH 2 ,3,4-oxadiazol-2-yl-CH=CH B.3308 1,2, 4-oxadiazol-3-yl-CH=CH B.3309 '5-CH 3 2, 4-oxadiazol-3-yl-CH=CH B. 3310 5-CF 3 -1 4-oxadiazol-3-yl-CH=CH B.3311 5-Cl-i, 2, 4-oxadiazol-3-yl-CH=CH B.3312 5-CH(CH 3 2 -i,2,4-oxadiazol-3-yl-CH=CH B. 3313 1,2, 4-triazol-3-yl-CH=CH B.3314 i-CH 3 2, 4-triazol-3-yl-CH=CH B.3315 5-CH 3 -1,2 ,4-triazol-3-yl-CH=CH B.3316 5-CF 3 2, 4-triazol-3-yl-CH=CH B. 3317 5-OCH 3 -1 4-triazol-3-yl-CH=CH B.3318 5-Cl-i, 2, 4-triazol-3-yl-CH=CH B.3319 5-CH (CH 3 2 4-triazol-3-yl-CH=CH B.3320 i-C 6
H
5 4-triazol-3-yl-CH=CH B. 3321 1,3, B. 3322 2-CH 3 3, B. 3323 2-CF 3 3, B.3324 2-OCH 3 -1,3,4-thiadiazol-5-yl-CH=CH B. 3325 2-Cl-i, 3, B.3326 2-CH(CH 3 2 -1,3,4-thiadiazol-5-yl-CH=CH B. 3327 1,3, 4-thiadiazol-2-yl-CH=CH B.3328 5-CH 3 3,4-thiadiazol-2-yl-CH=CH B.3329 5-CF 3 -1,3,4-thiadiazol-2-yl-CH=CH B.3330 5-OCH 3 3, 4-thiadiazol-2-yl-CH=CH B. 3331 5-Cl-i, 3, 4-thiadiazol-2-yl-CH=CH B.3332 5-CH(CH 3 2 4-thiadiazol-2-yl-CH=CH B. 3333 5-C 6
H
5 3, 4-thiadiazol-2-yl-CH=CH B. 3334 1,2, 4-thiadiazol-3-yl-CH=CH 0050/46043 291 The compounds I are suitable as fungicides.
The compounds I are distinguished by an outstanding activity against a wide spectrum of phytopathogenic fungi, in particular from the classes of the Ascomycetes, Phycomycetes and Basidiomycetes. Some of them act systemically and can be employed in crop protection as foliar- and soil-acting fungicides.
They are particularly important for controlling a large number of fungi which infect various crop plants, such as wheat, rye, barley, oats, rice, maize, grass, cotton, soya, coffee, sugar cane, grapevines, fruit species, ornamentals and vegetable species such as cucumbers, beans and cucurbits, and also the seeds of these plants.
Specifically, they are suitable for controlling the following plant diseases: Erysiphe graminis (powdery mildew) in cereals, Erysiphe cichoracearum and Sphaerotheca fuliginea in cucurbits, Podosphaera leucotricha in apples, Uncinula necator in grapevines, Puccinia species in cereals, Rhizoctonia species in cotton, rice and lawns, Ustilago species in cereals and sugar cane, Venturia inaequalis (scab) in apples, Helminthosporium species in cereals, Septoria nodorum in wheat, Botrytis cinerea (gray mold) in strawberries, vegetables and ornamentals, grapevines, Cercospora arachidicola in groundnuts, Pseudocercosporella herpotrichoides in wheat and barley, Pyricularia oryzae in rice, Phytophthora infestans in potatoes and tomatoes, Fusarium and Verticillium species in a variety of plants, Plasmopara viticola in grapevines and Alternaria species in vegetables and fruit.
Furthermore, the compounds I are suitable for controlling harmful fungi in the protection of materials (eg. wood, paper, fibers or wovens) and in the protection of stored products.
The compounds I are used by treating the fungi, or the plants, seeds, materials or the soil to be protected against fungal infection, with a fungicidally active amount of the active ingredients. Application is effected before or after infection of the materials, plants or seeds by the fungi.
They can be converted into the customary formulations, such as solutions, emulsions, suspensions, dusts, powders, pastes and granules. The use form depends on the specific purpose; in any case, it should guarantee fine and uniform distribution of the compounds according to the invention. The formulations are Y i :i I; 0050/46043 292 prepared in a known manner, eg. by extending the active ingredient with solvents and/or carriers, if desired using emulsifiers and dispersants, it also being possible to use other organic solvents as auxiliary solvents if water is used as the diluent.
Suitable auxiliaries are essentially: solvents, such as aromatics (eg. xylene), chlorinated aromatics (eg. chlorobenzenes), paraffins (eg. mineral oil fractions), alcohols (eg. methanol, butanol), ketones (eg. cyclohexanone), amines (eg. ethanolamine, dimethylformamide) and water; carriers, such as ground natural minerals (eg. kaolins, clays, talc, chalk) and ground synthetic rocks (eg. highly disperse silica, silicates); emulsifiers, such as non-ionic and anionic emulsifiers (eg. polyoxyethylene fatty alcohol ethers, alkylsulfonates and arylsulfonates) and dispersants, such as lignin-sulfite waste liquors and methylcellulose.
The fungicidal compositions generally comprise from 0.1 to preferably from 0.5 to 90, by weight of active ingredient.
Depending on the nature of the desired effect, the rate of application, when used for the protection of crops, is from 0.01 to 2.0 kg of active ingredient per ha.
In the treatment of seed, amounts of from 0.001 to 0.1 g, preferably 0.01 to 0.05 g, of active ingredient are generally required per kilogram of seed.
When used in the protection of materials or stored products, the rate of application of active ingredient depends on the field of application and on the desired effect. Usual rates of application in the protection of materials are, for example, 0.001 g to 2 kg, preferably 0.005 g to 1 kg, of active ingredient per cubic meter of material treated.
In their use form as fungicides, the compositions according to the invention can also be present together with other active ingredients, the [sic] eg. with herbicides, insecticides, growth regulators, fungicides, or else with fertilizers.
If they are mixed with fungicides, this frequently results in a widened fungicidal spectrum of action.
The following list of fungicides together with which the compounds according to the invention can be used is intended to illustrate possible combinations, but not by way of limitation: 0050/46043 293 Sulfur, dithiocarbamates and their derivatives, such as iron(III) dimethyldithiocarbamate, zinc dimethyldithiocarbamate, zinc ethylenebisdithiocarbamate, manganese ethylenebisdithiocarbamate, manganese zinc ethylenedialninebisdithiocarbamate, tetramethylthiuram disulfides [sic], ammonia complex of zinc (N,N-ethylenebisdithiocarbamate), ammonia complex of zinc (N,N '-propylenebisdithiocarbamate), zinc (N,N '-propylenebisdithiocarbamate), N, N -polypropylenebis (thiocarbamoyl) disulfide; Nitro derivatives, such as dinitro(1-methylheptyl)phenyl crotonate, 2-sec-butyl-4 ,6-dinitrophenyl-3, 3-dimethyl acrylate, 2-sec-butyl-4, 6-dinitrophenyl isopropyl carbonate, di-isopropyl heterocyclic substances, such as 2 -heptadecyl-2-imidazoline acetate, 2, 4-dichloro-6- (o-chloroanilino )-s-triazine, o, 0-diethyl phthalimidophosphonothioate, 5-amino-l-[bis (dimethylamino)phosphynyl I-3-phenyl-1 triazole, 2, 3-dicyano-1, 4-dithioanthraquinone, 2 -thiol,3dithiolo[4,5-b]qunoxaline, methyl 1- (butylcarbamoyl 2 -benzimidazolecarbamate, 2-methoxycarbonyl.
aminobenzimidazole, furyl-(2) )-benzimidazole, 2-(thiazolyl- -benzimidazole, N- 2 -tetrachloroethylthio )tetrahydrophthalimide, N-trichloromethylthiotetrahydrophthalimide, N-trichloromethylthiophthalimide, N-dichlorofluoromethylthio.N N'-dimethyl-N-phenylsulfuric diamide, 5 -ethoxy-3-trichloromethyl-1,2, 3-thiadiazole, 2-thiocyanatomethylthiobenzothiazole, 1, 4-dichloro-2 benzene, 4- 2 -chlorophenylhydrazono) 3 pyridine-2-thio-l-oxide, 8-hydroxyquinoline and its copper salt, 2, 3 -dihydro-5-carboxanilido-6-methyl-1,4-oxathiine, 2, 3-dihydro- 5-carboxanilido-6-methyl-1,4-oxathiine 4,4-dioxide, 2-methyl-5, 6dihydro-4H-pyran-3-carboxanilide, 2 -methylfuran-3-carboxanilide, 2, S-dimethylfuran-3-carboxanilide, 2,4, 5-trimethylfuran-3carboxanilide, N-cyclohexyl-2, S-dimethylfuran-3-carboxamide, N-cyclohexyl-N-methoxy.2 -dimethylfuran-3-carboxamide, 2-methylbenzanilide, 2-iodobenzanilide N-formyl-N-morpholine- 2 2 ,2-trichloroethyl acetal, piperazin-1, 4-diylbis( 2trichloroethyl) formamide [sic]J, 1- 4-dichloroanilino) -1formylamino-2 2 -trichloroethane, 2, 6-dimethyl-Ntridecylmorpholine and its salts, 2 ,6-dimethyl-N-cyclododecylmorpholine and its salts, N- (p-tert-butylphenyl )-2-methylpropyl J-cis-2, 6 -dimethylmorpholine, N- (p-tert-butylphenyl) -2-methylpropyl Ipiperidine, 1- 4-dichlorophenyl ethyl-i, 3-dioxolan-2-yl-ethyl -H-1 4-triazole, 1P[ 2 2 ,4-dichlorophenyl)-4-N-propyl- 1, 3-dioxolan-2-yl- 0050/46043 294 ethylJ-lH-1,2 ,4-triazole, N-(N-propyl)-N-(2,4 ,6-trichlorophenoxyethyl)-N'-imidazolylurea, 1-(4-chlorophenoxy)-3, 3dimethyl-l-( lH-l,2,4-triazol-1-yl)-2-butanone, 1-(4-chlorophenoxy ,3-dimethyl--( 1H-1, 2, 4-triazol-1-yl )-2--butanol, a- (2-chiorophenyl (4-chiorophenyl) 2 -dimethylamino-4-hydroxy-6..methylpyrimidine, bis- (p-chlorophenyl )-3-pyridinemethanol, 1, 2-bis- (3-ethoxycarbonyl-2-thioureido) benzene, 1, 2-bis- (3-methoxycarbonyl- 2-thioureido )benzene, and various fungicides, such as dodecylguanidine acetate, 3- 5-dimethyl-2-oxycyclohexyl )-2-hydroxyethyl Iglutarimide, hexachlorobenzene, DL-methyl N- 6-dimethyiphenyl )-N-furoyl- 2-alaninate, DL-methyl N- 6-dimethyiphenyl (2 '-methoxyacetyl) alaninate, N- 6-dimethyiphenyl )-N-chloroacetyl-D,
L-
2-aminobutyrolactone, DL-methyl N- 6-dimethyiphenyl (phenylacetyl )alaninate, 5-methyl-5-vinyl-3- 5-dichiorophenyl dioxo-1 ,3-oxazolidine, 3- 5-dichiorophenyl methoxymethyl]-1,3-oxazolidine-2, 4-dione [sic], phenyl )-l-isopropylcarbamoylhydantoin, N- 5-dichiorophenyl) 1, 2-dimethylcyclopropane-1, 2-dicarboximide, 2-cyano (ethylaminocarbonyl )-2-methoximinoj acetamide, 1-12- 4-dichioroazolyl-l-methyl )benzhydryl alcohol, N- (3-chloro-2, 6-dinitro- 4-trifluoromethyiphenyl) -5-trifluoromethyl-3-chloro-2-aminopyridine, (bis-(4-fluorophenyl)methylsilyl)- methyl)-1H-1,2,4triazole.
Strobilurins such as methyl E-methoxyimino[a-(o-tolyloxy)-otolyl]acetate, methyl 6-(2-cyanophenoxy)pyrimidin-4-yloxy ]phenyl}-3-methoxyacrylate, methyl-E-methoxyimino[a-(2-phenoxyphenyl) Jacetamide, methyl-E-methoxyimino 5-dimethylphenoxy) -o-tolyl Jacetamide.
Anilinopyrimidines such as N- 6-dimethylpyrimidin-2-yl )aniline, N-[4-methyl-6-( l-propynyl)pyrimidin-2-yl]aniline, N-(4-methyl- 6 -cyclopropylpyrimidin-2-yl )aniline.
Phenylpyrroles such as 4-(2,2-difluoro-1, 3-benzodioxol-4-yl)pyrrole-3-carbonitrile.
Cinnamainides such as (4-chlorophenyl 4-dimethoxyphenyl )acryloyl ]morpholide.
The compounds of the formula I are furthermore suitable for effectively controlling pests from the classes of the insects, arachnids and nematodes. They can be employed as pesticides in 0050/46043 295 crop protection and in the hygiene, stored-product and veterinary sectors.
The harmful insects include, from the order of the lepidopterans (Lepidoptera), for example, Agrotis ypsilon, Agrotis segetum, Alabama argillacea, Anticarsia genimatalis, Argyresthia conjugella, Autographa gamma, Bupalus piniarius, Cacoecia murinana, Capua reticulana, Cheimatobia brumata, Choristoneura fumiferana, Choristoneura occidentalis, Cirphis unipuncta, Cydia pomonella, Dendrolimus pini, Diaphania nitidalis, Diatraea grandiosella, Earias insulana, Elasmopalpus lignosellus, Eupoecilia ambiguella, Evetria bouliana, Feltia subterranea,' Galleria mellonella, Grapholitha funebrana, Grapholitha molesta, Heliothis armigera, Heliothis virescens, Heliothis zea, Hellula undalis, Hibernia defoliaria, Hyphantria cunea, Hyponomeuta malinellus, Keiferia lycopersicella, Lambdina fiscellaria, Laphygma exigua, Leucoptera coffeella, Leucoptera scitella, Lithocolletis blancardella, Lobesia botrana, Loxostege sticticalis, Lymantria dispar, Lymantria monacha, Lyonetia clerkella, Malacosoma neustria, Mamestra brassicae, Orgyia pseudotsugata, Ostrinia nubilalis, Panolis flammea, Pectinophora gossypiella, Peridroma saucia, Phalera bucephala, Phthorimaea operculella, Phyllocnistis citrella, Pieris brassicae, Plathypena scabra, Plutella xylostella, Pseudoplusia includens, Rhyacionia frustrana, Scrobipalpula absoluta, Sitotroga cerealella, Sparganothis pilleriana, Spodoptera frugiperda, Spodoptera littoralis, Spodoptera litura, Thaumatopoea pityocampa, Tortrix viridana, Trichoplusia ni, Zeiraphera canadensis.
From the order of the beetles (Coleoptera), for example, Agrilus sinuatus, Agriotes lineatus, Agriotes obscurus, Amphimallus solstitialis, Anisandrus dispar, Anthonomus grandis, Anthonomus pomorum, Atomaria linearis, Blastophagus piniperda, Blitophaga undata, Bruchus rufimanus, Bruchus pisorum, Bruchus lentis, Byctiscus betulae, Cassida nebulosa, Cerotoma trifurcata, Ceuthorrhynchus assimilis, Ceuthorrhynchus napi, Chaetocnema tibialis, Conoderus vespertinus, Crioceris asparagi, Diabrotica longicornis, Diabrotica 12-punctata, Diabrotica virgifera, Epilachna varivestis, Epitrix hirtipennis, Eutinobothrus brasiliensis, Hylobius abietis, Hypera brunneipennis, Hypera postica, Ips typographus, Lema bilineata, Lema melanopus, Leptinotarsa decemlineata, Limonius californicus, Lissorhoptrus oryzophilus, Melanotus communis, Meligethes aeneus, Melolontha hippocastani, Melolontha melolontha, Oulema oryzae, Ortiorrhynchus sulcatus, Otiorrhynchus ovatus, Phaedon cochleariae, Phyllotreta chrysocephala, Phyllophaga sp., Phyllopertha horticola, Phyllotreta nemorum, Phyllotreta 0050/46043 296 striolata, Popillia japonica, Sitona lineatus, Sitophilus granaria.
From the order of the dipterans (Diptera), for example, Aedes aegypti, Aedes vexans, Anastrepha ludens, Anopheles maculipennis, Ceratitis capitata, Chrysomya bezziana, Chrysomya hominivorax, Chrysomya macellaria, Contarinia sorghicola, Cordylobia anthropophaga, Culex pipiens, Dacus cucurbitae, Dacus oleae, Dasineura brassicae, Fannia canicularis, Gasterophilus intestinalis, Glossina morsitans, Haematobia irritans, Haplodiplosis equestris, Hylemyia platura, Hypoderma lineata, Liriomyza sativae, Liriomyza trifoii, Lucilia caprina, Lucilia cuprina, Lucilia sericata, Lycoria pectoralis, Mayetiola destructor, Musca domestica, Muscina stabulans, Oestrus ovis, Oscinella frit, Pegomya hysocyami, Phorbia antiqua, Phorbia brassicae, Phorbia coarctata, Rhagoletis cerasi, Rhagoletis pomonella, Tabanus bovinus, Tipula oleracea, Tipula paludosa.
From the order of the thrips (Thysanoptera), for example, Frankliniella fusca, Frankliniella occidentalis, Frankliniella tritici, Scirtothrips citri, Thrips oryzae, Thrips palmi, Thrips tabaci.
From the order of the hymenopterans (Hymenoptera), for example, Athalia rosae, Atta cephalotes, Atta sexdens, Atta texana, Hoplocampa minuta, Hoplocampa testudinea, Monomorium pharaonis, Solenopsis geminata, Solenopsis invicta.
From the order of the heteropterans (Heteroptera), for example, Acrosternum. hilare, Blissus leucopterus, Cyrtopeltis notatus, Dysdercus cingulatus, Dysdercus intermedius, Eurygaster integriceps, Euschistus impictiventris, Leptoglossus phyllopus, Lygus lineolaris, Lygus pratensis, Nezara viridula, Piesma quadrata, Solubea insularis, Thyanta perditor.
From the order of the homopterans (Homoptera), for example, Acyrthosiphon onobrychis, Adelges laricis, Aphidula nasturtii, Aphis fabae, Aphis pomi, Aphis sainbuci, Brachycaudus cardui, Brevicoryne brassicae, Cerosipha gossypii, Dreyfusia nordmannianae, Dreyfusia piceae, Dysaphis radicola, Dysaulacorthum pseudosolani, Empoasca fabae, Macrosiphum avenae, Macrosiphum. euphorbiae, Macrosiphon rosae, Megoura viciae, Metopolophium dirhodum, Myzodes persicae, Myzus cerasi, Nilaparvata lugens, Pemphigus bursarius, Perkinsiella saccharicida, Phorodon humuli, Psylla mali, Psylla pini, Rhopalomyzus ascalonicus, Rhopalosiphum maidis, Sappaphis mala, V1 0050/46043 297 Sappaphis mali, Schizaphis graminum, Schizoneura lanuginosa, Trialeurodes vaporariorum, Viteus vitifolii.
From the order of the termites (Isoptera), for example, Calotermes flavicollis, Leucotermes flavipes, Reticulitermes lucifugus, Termes natalensis.
From the order of the orthopterans (Orthoptera), for example, Acheta domestica, Blatta orientalis, Blattella germanica, Forficula auricularia, Gryllotalpa gryllotalpa, Locusta migratoria, Melanoplus bivittatus, Melanoplus femur-rubrum, Melanoplus mexicanus, Melanoplus sanguinipes, Melanoplus spretus, Nomadacris septemfasciata, Periplaneta americana, Schistocerca americana, Schistocerca peregrina, Stauronotus maroccanus, Tachycines asynamorus.
From the class of the Arachnoidea, for example, arachnids (Acarina), such as Amblyomma americanum, Amblyomma variegatum, Argas persicus, Boophilus annulatus, Boophilus decoloratus, Boophilus microplus, Brevipalpus phoenicis, Bryobia praetiosa, Dermacentor silvarum, Eotetranychus carpini, Eriophyes sheldoni, Hyalomma truncatum, Ixodes ricinus, Ixodes rubicundus, Ornithodorus moubata, Otobius megnini, Paratetranychus pilosus, Dermanyssus gallinae, Phyllocoptruta oleivora, Polyphagotarsonemus latus, Psoroptes ovis, Rhipicephalus appendiculatus, Rhipicephalus evertsi, Sarcoptes scabiei, Tetranychus cinnabarinus, Tetranychus kanzawai, Tetranychus pacificus, Tetranychus telarius, Tetranychus urticae.
From the class of the Nematodes, for example, root gall nematodes, eg. Meloidogyne hapla, Meloidogyne incognita, Meloidogyne javanica, cyst eelworms, eg. Globodera rostochiensis, Heterodera avenae, Heterodera glycines, Heterodera schachtii, Heterodera trifolii, stem eelworms and foliar nematodes, eg. Belonolaimus longicaudatus, Ditylenchus destructor, Ditylenchus dipsaci, Heliocotylenchus multicinctus, Longidorus elongatus, Radopholus similis, Rotylenchus robustus, Trichodorus primitivus, Tylenchorhynchus claytoni, Tylenchorhynchus dubius, Pratylenchus neglectus, Pratylenchus penetrans, Pratylenchus curvitatus, Pratylenchus goodeyi.
The active ingredients can be used as such, in the form of their formulations or the use forms prepared therefrom, eg. in the form of ready-to-spray solutions, powders, suspensions or dispersions, emulsions, oil dispersions, pastes, dusts, materials for spreading, or granules, by spraying, atomizing, dusting, spreading or pouring. The use forms depend entirely on the Aj r. .r 0050/46043 298 intended purposes; in any case, they should guarantee the finest possible distribution of the active ingredients according to the invention.
The concentrations of active ingredients in the ready-to-use preparations can be varied within substantial ranges.
In general, they are from 0.0001 to 10%, preferably 0.01 to 1%.
The active ingredients can also be used successfully for the ultra-low-volume method (ULV), it being possible to apply formulations comprising more than 95% by weight of active ingredient, or even the active ingredient without additives.
The rate of active ingredient applied for controlling pests is from 0.1 to 2.0, preferably 0.2 to 1.0, kg/ha under field conditions.
Suitable substances for the preparation of ready-to-spray solutions, emulsions, pastes or oil dispersions are mineral oil fractions of medium to high boiling point, such as kerosene or diesel oil, furthermore coal tar oils and oils of vegetable or animal origin, aliphatic, cyclic and aromatic hydrocarbons, eg.
benzene, toluene, xylene, paraffin, tetrahydronaphthalene, alkylated naphthalenes or their derivatives, methanol, ethanol, propanol, butanol, chloroform, carbon tetrachloride, cyclohexanol, cyclohexanone, chlorobenzene, isophorone, strongly polar solvents, eg. dimethylformamide, dimethyl sulfoxide, N-methylpyrrolidone and water.
Aqueous use forms can be prepared from emulsion concentrates, pastes or wettable powders (sprayable powders, oil dispersions) by adding water. To prepare emulsions, pastes or oil dispersions, the substances, as such or dissolved in an oil or solvent, can be homogenized in water by means of wetting agents, adhesives, dispersants or emulsifiers. Alternatively, it is possible to prepare concentrates composed of active ingredient, wetting agents, adhesives, dispersants or emulsifiers and, if desired, solvents or oil, and these concentrates are suitable for dilution with water.
Suitable surfactants are alkali metal salts, alkaline earth metal salts and ammonium salts of lignosulfonic acid, naphthalenesulfonic acid, phenolsulfonic acid, dibutylnaphthalenesulfonic acid, alkylarylsulfonates, alkyl sulfates, alkyl sulfonates, fatty alcohol sulfates and fatty acids and their alkali metal and alkaline earth metal salts, salts of sulfated fatty alcohol :L "s 1 Uif: 0050/46043 299 glycol ether, condensates of sulfonated naphthalene and naphthalene derivatives with formaldehyde, condensates of naphthalene or of naphthalenesulfonic acid with phenol and formaldehyde, polyoxyethylene octylphenol ether, ethoxylated isooctylphenol, octylphenol, nonylphenol, alkylphenyl polyglycol ethers, tributylphenyl polyglycol ether, alkylaryl polyether alcohols, isotridecyl alcohol, fatty alcohol/ethylene oxide condensates, ethoxylated castor oil, polyoxyethylene alkyl ethers, ethoxylated polyoxypropylene, lauryl alcohol polyglycol ether acetal, sorbitol esters, lignosulfite waste liquors and methylcellulose.
Powders, materials for spreading and dusts can be prepared by mixing or concomitantly grinding the active ingredients with a solid carrier.
The formulations generally comprise from 0.01 to 95% by weight, preferably from 0.1 to 90% by weight, of the active ingredient.
The active ingredients are employed in a purity of from 90% to 100%, preferably 95% to 100% (according to NMR spectrum).
Examples of formulations are: I. 5 parts by weight of a compound according to the invention are mixed intimately with 95 parts by weight of finely divided kaolin. This gives a dust which comprises 5% by weight of the active ingredient.
II. 30 parts by weight of a compound according to the invention are mixed intimately with a mixture of 92 parts by weight of pulverulent silica gel and 8 parts by weight of paraffin oil which has been sprayed onto the surface of this silica gel.
This gives a formulation of the active ingredient with good adherence (comprises 23% by weight of active ingredient).
III.10 parts by weight of a compound according to the invention are dissolved in a mixture composed of 90 parts by weight of xylene, 6 parts by weight of the adduct of 8 to 10 mol of ethylene oxide to 1 mol of oleic acid N-monoethanolamide, 2 parts by weight of calcium dodecylbenzenesulfonate and 2 parts by weight of the adduct of 40 mol of ethylene oxide to 1 mol of castor oil (comprises 9% by weight of active ingredient).
IV. 20 parts by weight of a compound according to the invention are dissolved in a mixture composed of 60 parts by weight of cyclohexanone, 30 parts by weight of isobutanol, 5 parts by weight of the adduct of 7 mol of ethylene oxide to 1 mol of
A/,
L c 4 0050/46043 300 isooctylphenol and 5 parts by weight of the adduct of 40 mol of ethylene oxide to 1 mol of castor oil (comprises 16% by weight of active ingredient).
V. 80 parts by weight of a compound according to the invention are mixed thoroughly with 3 parts by weight of sodium diisobutylnaphthalene-alpha-sulfonate, 10 parts by weight of the sodium salt of a lignosulfonic acid from a sulfite waste liquor and 7 parts by weight of pulverulent silica gel, and the mixture is ground in a hammer mill (comprises 80% by weight of active ingredient).
VI. 90 parts by weight of a compound according to the invention are mixed with 10 parts by weight of N-methyl-a-pyrrolidone, giving a solution which is suitable for use in the form of microdrops (comprises 90% by weight of active ingredient).
parts by weight of a compound according to the invention are dissolved in a mixture composed of 40 parts by weight of cyclohexanone, 30 parts by weight of isobutanol, 20 parts by weight of the adduct of 7 mol of ethylene oxide to 1 mol of isooctylphenol and 10 parts by weight of the adduct of 40 mol of ethylene oxide to 1 mol of castor oil. Pouring the solution into 100 000 parts by weight of water and finely distributing it therein gives an aqueous dispersion comprising 0.02% by weight of the active ingredient.
parts by weight of a compound according to the invention are mixed thoroughly with 3 parts by weight of sodium diisobutylnaphthalene-a-sulfonate, 17 parts by weight of the sodium salt of a lignosulfonic acid from a sulfite waste liquor and 60 parts by weight of pulverulent silica gel, and the mixture is ground in a hammer mill. Finely distributing the mixture in 20 000 parts by weight of water gives a spray mixture which comprises 0.1% by weight of the active ingredient.
Granules, eg. coated granules, impregnated granules and homogeneous granules, can be prepared by binding the active ingredients to solid carriers. Examples of solid carriers are mineral earths, such as silica gel, silicas, silica gels [sic], silicates, talc, kaolin, attaclay, limestone, lime, chalk, bole, loess, clay, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, ground synthetic materials, fertilizers, eg. ammonium sulfate, ammonium phosphate, ammonium nitrate, ureas and products of vegetable origin, such as cereal meal, tree bark /T OV 0050/46043 301 meal, wood meal and nutshell meal, cellulose powders and other solid carriers.
Various types of oils, or herbicides, fungicides, other pesticides and bactericides can be added to the active ingredients, if desired only immediately prior to use (tank mix). These agents can be admixed to the agents according to the invention in a weight ratio of 1:10 to 10:1.
Synthesis examples The protocols given in the synthesis examples below were used for obtaining other compounds I by changing the starting compounds as appropriate. The resulting compounds are given in the tables which follow together with physical data.
Example 1: Methyl 2 -(isopropyl)-l-(methyl)-2-(oxo)ethylidene]amino]oxy] methyl]-a-(methoxymethylene)phenylacetate
(CH
3 2 HC H NOCH 2 II
C=CHOCH
3
O
C0 2
CH
3 11 g of a 30% strength solution of sodium methylate in methanol are added to a solution of 8 g (62 mmol) of l-isopropyl-1,2propanedione 2-oxime in 50 ml of N,N-dimethylformamide. The mixture is stirred for 30 minutes at room temperature, a solution of 18.6 g (68 mmol) of methyl 2-(bromomethyl)-a-(methoxymethylene)phenylacetate in 50 ml of N,N-dimethylformamide is then added dropwise, and the mixture is stirred for approximately 1 hour at 40°C. The reaction solution is subsequently treated with water and extracted using methyl tert-butyl ether. Drying the organic extracts over sodium sulfate and concentration on a rotary evaporator gives 18 g of a yellow solid. After recrystallization from hexane, filtration with suction and drying in a vacuum drying oven, 15 g of the title compound are obtained in the form of a pale yellow solid 67-69 0
C).
IR [cm-1] (KBr): 768, 997, 1009, 1109, 1127, 1210, 1254, 1630, 1683, 1699, 2950.
i P tvl 'Nr 0050/46043 Example 2: 302 Methyl 2 -(allyloxy)imino-2-(isopropyl)--(meth.
yl )ethyl idene Iamino ]oxy ]methyl (methoxymethylene )phenylacetate
H
3 0 0H 2
CHCH
2 ON~ NOCH 2 q
C=CHOCH
3
CH(CH
3 2 I C0 2 0H 3 0.7 g (9 mmol) of o-allylhydroxylamine and 0.9 g (4.5 mmol) of p-toluenesulfonic acid are added to a solution of 1.5 g nimol) of methyl 2 2 -(isopropyl))--(methyl)-2-(oxo)ethylidene Jamino ]oxy]methyl (methoxymethylene )phenylacetate in 60 ml of methanol. The reaction solution is left to stand for 4 days at room temperature, water is subsequently added, and the mixture is extracted using methyl tert-butyl ether. The combined organic extracts are dried over sodium sulfate and concentrated. After column chromatography on silica gel (methyl tert-butyl ether/hexane), the title compound is obtained in the form of two isomers [isomerism in the side chain, E) and respectively].
Isomer 1 (0.3 g; pale yellow oil) 1 H NMR (CDCl 3 1.16 6H); 1.99 3H); 3.50 3.81 3H); 4.60 2H); 5.08 5.97 (in, 1H); 7.12-7.46 (in, 4H); (in, 1H) 2H) 7.56 (s, 3.67 3H); 5.25 (mn, 2H); 1H) ppm.
Isomer 2 (0.6 g; white solid; m.p. 58-60*C) 1 H NMR (CDCl 3 8 1.08 6H); 3.81 3H); 5.96 (in, 1H); 2.00 3H); 2.71 (mn, 1H); 4.53 2H); 5.06 2H); 7.12-7.46 (in, 4H); 7.56 (s, 3.67 3H); 5.21 (mn, 2H); IH) ppm.
Example 3: Methyl 2 2 -(isopropyl)-1-(methyl)-2-(oxo)ethylidene Iamino Joxylmethyl I-a- (ethylidene )phenylacetate
H
3
C
(0H 3 2 CH -NOCH 2 Y -C=CHCH 3 01 C0 2
CH
3 0050/46043 303 A solution of 9 g (33 mmol) of methyl 2-(bromomethyl)-a-ethylidene-phenylacetate in 50 ml of N,N-dimethylformamide is treated with 9.2 g (67 mmol) of potassium carbonate, 4.3 g of 1-isopropyl-l,2-propanedione 2-oxime are added, and the mixture is stirred for 2 hours at 50 0 C. The reaction mixture is subsequently poured into water and extracted using methyl tert-butyl ether.
The combined organic extracts are washed with water, dried over sodium sulfate and concentrated. After column chromatography on silica gel (cyclohexane/ethyl acetate), 7.8 g of the title compound are obtained as a pale yellow oil.
1 H NMR (CDC1 3 6= 1.06 6H); 1.62 3H); 1.90 3H); 3.86 1H); 3.70 3H); 5.13 2H); 7.08-7.50 4H) ppm.
Example 4: Methyl 2 -(isopropyl)-2-(methoxyimino)-1-(methyl)ethylidene]amino]oxy]methyl]-a-(ethylidene)phenylacetate H3C= NOCH 2 HsCON--
C=CHCH
3 CH(CH3)2 CO2CH 3 A solution of 2 g (6.3 mmol) of methyl 2-[[[[2-(isopropyl)- 1-(methyl)-2-(oxo)ethylidene]amino]oxy]methyl]-a-(ethylidene)phenylacetate in 50 ml of methanol is treated with 7.9 g of a strength solution of O-methylhydroxylamine hydrochloride in methanol and 2-3 g of molecular sieve The reaction solution is left to stand for 3 days at room temperature and is then stirred for 4 hours at 40 0 C. After molecular sieve has been removed by filtration, the solution is poured into ice-water and extracted using methyl tert-butyl ether. The combined organic extracts are washed with water, dried over sodium sulfate and concentrated.
After column chromatography on silica gel (cyclohexane/ethyl acetate), 1.7 g of the title compound are obtained in the form of an isomer mixture (isomerism in the side chain, isomers 1:2) as a pale yellow oil.
IR [cm- 1 (film): 761, 907, 1013, 1038, 1208, 1252, 1435, 1719, 2937, 2963.
0050/46043 304 Example 5: Methyl 2 -(isopropyl)-2-(methoxyimino)-1-(methyl)ethylidenelamino]oxy~methyl]-a- (methoxyimino )phenylacetate
H
3
=NOCH
2 H3CONC=NOCH 3 CH(0H 3 2
I
COU
2 CH1 3 1 equivalent of sodium methylate (30% strength solution in methanol) is added to a solution of 49.7 g (315 mnmol) of (E,E (isopropyl (methoxyimino-propan-2-one 2-oxime in 400 ml of N,N'-dimethylformamide, and the mixture is stirred for minutes at room temperature. A solution of 82.8 g (290 mmol) of methyl 2 -(bromomethyl)-a-methoxyiminophenylacetate in 200 ml of N,N-dimethylformamide is subsequently added dropwise. The reaction mixture is stirred for 1 hour at room temperature and subsequently poured into ice-water. The solid which has precipitated is filtered off with suction. After repeated washing with water and pentane, 94.5 g of a crystalline solid of melting point 92-94*C are obtained.
1 H NMR (CDCl 3 6=1.12 6H); 1.96 3H); 3.45 (in, 1H); 3.84 3H); 3.89 3H); 4.04 3H); 5.05 2H); 7.15-7.48 (in, 4H) ppm.
Example 6 N-Monomethyl-(E,E,E)-2-[ 2 -(isopropyl)-2-(methoxyimino)-l- (methyl )ethylidene Jamino ]oxy Imethyl I-a- (methoxyimino) phenylacetamide =3
NOCH
2 3 C=NOCH 3
CONHCH
3 g (138 inmol) of methyl 2 -[II[[2-(isopropyl)-2-(methoxy.
imino) -1-(methyl )ethylidene ]amino] oxy ]methyl I-a- (methoxyimino)-phenylacetate are dissolved in 500 ml of tetrahydrofuran, 107 g of a 40% strength aqueous monomethylamine solution are added, and the mixture is stirred for 30-60 minutes at 50 0 C. The 0050/46043 305 mixture is subsequently treated with water and extracted using methyl tert-butyl ether. The organic phase is washed with water, dried over Na 2
SO
4 and concentrated. This gives 41 g of a brown solid which is purified by being suspended in pentane. After filtration with suction, washing the residue and drying it, 37 g of the title compound are isolated in the form of colorless crystals. 78-79°C.
1 H NMR (CDCl 3 6 1.13 6H); 1.95 3H); 2.88 3H); 3.46 1H); 3.89 3H); 3.94 3H); 5.06 2H); 6.72 (s broad, 1H); 7.15-7.46 4H) ppm.
Example 7: Methyl 2 -methoxyimino)-l-(methyl)-2-(phenoxymethyl)ethylidene]amino]oxy]methyl]-a-(methoxyimino)phenylacetate
H
3
C
HNOCH
2
H
3 CON=
C=NOCH
3
CH
2
OC
6
H
5
I
CO
2
CH
3 0.4 g of O-methylhydroxylamine hydrochloride and 1.2 g of pyridine are added to a solution of 2 g of methyl yl)-2-(oxo)-2-(phenoxymethyl)ethylidene]amino]oxy]methyl]-a- (methoxyimino)phenylacetate in 5 ml of methanol. The reaction solution is stirred for 60 minutes at room temperature, the residue is taken up in dichloromethane, the organic phase is washed using dilute hydrochloric acid and water. The organic phase is dried over sodium sulfate and concentrated. Crystallization of the residue from pentane gives 0.7 g of the title compound in the form of pale red crystals 81-83 0
C).
Example 8: N-monomethyl-2-[[[[2-(methoxyimino)-l-(methyl)-2- (phenoxymethyl)ethylidene]amino]oxy]methyl]-a-(methoxyimino)phenylacetamide
H
a
C
NOCH
2
H
3 CON= C=NOCH 3 CH20C6H5 I
CONHCH
3 C"
A^
0050/46043 306 g of methyl 2-[[[[2-(methoxyimino)-l-(methyl)-2-(phenoxymethyl)ethylidene]amino]oxy]methyl]-a-(methoxyimino)phenylacetate is dissolved in 5 ml of tetrahydrofuran, 0.5 g of 40% strength aqueous monomethylamine solution is added, and the mixture is stirred at room temperature. The reaction mixture is concentrated and the residue triturated with pentane. After the precipitate has been filtered off and washed with pentane, 0.5 g of the title compound is obtained in the form of pale pink crystals (m.p.
136-138°C).
Example 9: Methyl 2-[[[[2-bromomethyl)-1-(methyl)-2-(oxo)ethylidene]amino]oxy]methyl]-a-(methoxyimino)phenylacetate HaC
NOCH
2
C=NOCH
3
CH
2 Br I
CO
2
CH
3 First, 5 ml of a solution of 20.8 g of bromine in 20 ml of chloroform are added dropwise at 40°C to a solution of 39.8 g of methyl 2-[[[[1,2-(dimethyl)-2-(oxo)ethylidene]amino]oxy]methylj-a-(methoxyimino)phenylacetate in 200 ml of chloroform. After the reaction has started up, the remaining bromine solution is added dropwise in such a way that the temperature can be kept at 40-500C. After reaction of the bromine has ended (decoloration, temperature drop), the course of the reaction is monitored by thin-layer chromatography. If starting compound is still present, more bromine solution is added dropwise until the reaction is complete (40°C, TLC check). The reaction mixture is allowed to cool to room temperature, water is added, and the mixture is neutralized using sodium hydrogen carbonate solution. The organic phase is separated off, washed with sodium hydrogen carbonate solution and with water, dried over sodium sulfate and concentrated. This gives the title compound in the form of a dark oil The crude product can be reacted further without being purified first.
1 H NMR (CDCl 3 6 [ppm] 1.94 3.86 4.04 (s,3H); 4.35 5.18 7.15-7.0 (m,4H) Jqj 0050/46043 307 Example 10: Methyl 2 -(4-chlorophenoxymethyl)-l-methyl-2oxoethylidene]amino]oxy]methyl]-a-(methoxyiminophenylacetate HaC NOCH 0 NH C=NOCH [4-CI-C 6 H4]-O-CH 2 C C0 2
CH
3 15.7 g of potassium carbonate and 11 g of 4-chlorophenol are added to a solution of 21.9 g of methyl 2 -[[[[2-(bromomethyl)- 1-(methyl)-2-(oxo)ethylidene]amino]oxy]methyl]-a-(methoxyimino)phenylacetate in 150 ml of acetone and stirred for 24 hours at room temperature. The reaction mixture is concentrated on a rotary evaporator and the residue which remains is taken up in ethyl acetate. The organic phase is washed with water, dried over Na 2 S0 4 and concentrated. Purification by column chromatography on silica gel gives the title compound in the form of a crystalline solid (10.8 110-114 0
C.
Example 11: Methyl 2-[[[[2-(4-chlorophenoxymethyl)-2-(ethoxyimino)-1-(methyl)ethylidene]amino]oxymethyl]-a- (methoxyimino)phenylacetate
H
3
C
NOCH
2
H
5
C
2 C=NOCH 3 [4-CI-C 6
H
4 ]-0-CH 2
I
C0 2
CH
3 0.6 g of O-ethylhydroxylamine hydrochloride and 1.4 g of pyridine are added to a solution of 2.5 g of methyl 2-[[[[2-(4-chlorophenoxymethyl)--(methyl)-2-(oxo)ethylidene]amino]oxy]methyl]a-(methoxyimino)-phenylacetate in 5 ml of methanol. The reaction solution is stirred for 18 hours at room temperature, taken up in dichloromethane and washed with dilute hydrochloric acid and water. Concentration on a rotary evaporator gives 2.7 g of the title compound in the form of a crystalline solid. 84-87 0
C.
'a V" t'\ n V- 0050/46043 308 Example 12 3-(Methoxyimino)-l-(phenyl)pent-l-yn-4-one 4-oxime
CH
3
H
3 CO- NOH
III
A solution of 1.6 g of l-(phenyl)pent-l-yne-3,4-dione 4 -oxime in ml of methanol is treated with 2 g of pyridine and 4.9 g of an 18% strength solution of O-methylhydroxylamine hydrochloride in methanol and the mixture is stirred for 24 hours at room temperature (approximately 25 0 The reaction solution is taken up in tert-butyl methyl ether and treated with 10% strength hydrochloric acid. The aqueous phase is extracted using tert-butyl methyl ether. The organic phases are subsequently washed using 10% strength hydrochloric acid and water and dried over Na 2
SO
4 and the solvent is distilled off under reduced pressure. This gives 1.4 g of the title compound of a colorless solid (Yield 140-144°C.
Example 13: Methyl 2 -(methoxyimino)-l-(methyl)-2-(phenylethyn-1-yl)ethylidene]amino]oxy]methyl]-a-(methoxyimino)phenylacetate
CH
3
H
3 CO* N OCH 2 i 1II C=NOCH 3 S CO 2
CH
3 1.4 g of a 30% strength solution of sodium methylate in methanol is added to a solution of 1.4 g of l-(methoxyimino)-l-(phenylethyn-l-yl)propan-2-one 2-oxime in 20 ml of N,N-dimethylformamide and the mixture is stirred for 10 minutes at room temperature.
A
solution of 2.1 g of methyl 2 -(bromomethyl)-a-methoxyiminophenylacetate in 20 ml of N,N-dimethylformamide is subsequently added dropwise. The reaction mixture is stirred for 1 hour at room temperature, poured into water and extracted using tert-butyl methyl ether. The organic phase is washed with water, dried over Na 2
SO
4 and filtered, and the filtrate is concentrated under reduced i' ,t 0050/46043 309 pressure. Crystallization of the oily residue from methanol gives 1.9 g of the title compound (yield m.p. 100-104 0
C.
Example 14 N-monomethyl-2-[[[[2-(methoxyimino)-l-(methyl)-2-(phenylethyn-1-yl)ethylidene]amino]oxy]methyl]-a-(methoxyimino)phenylacetamide
CH
3
H
3 CO-' N OCH 2 III
C=NOCH
3
CONHCH
3 1 g of the ester of Example 13 is dissolved in 50 ml of tetrahvdrofuran, 1.4 g of a 40% strength aqueous monomethylamine solution are added, and the mixture is stirred for 20 hours at room temperature. The reaction mixture is subsequently poured into water and extracted using tert-butyl methyl ether. The organic phase is washed with water, dried over Na 2
SO
4 and filtered, and the filtrate is concentrated under reduced pressure. Crystallization of the oily residue from methanol gives 0.8 g of the title compound as a solid (yield m.p. 131-133"C.
V/ II j 0050/46043 Table I.A 310
=NOCH
2
N
S C=CHCH 3 C0 2 0H 3 No. R 2 RR4Data 1 CH 3
C
2
H
5
CH
3 oil, IR (film) 877, 893, 956, 1017, 1051, 1208, 1252, 1435, 1719, 2939 2 CH 3
C
2
H
5
C
2
H
5 oil, IR (film) 877, 918, 956, 1038, 1050, 1208, 1252, 1435, 1719, 3 CH 3
C
2
H
5 n-C 3
H
7 oil, IR (film) 881, 907, 959, 988, 1037, 1252, 1435, 1720, 2938, 2968 4 CH 3
CH(CH
3 2
CH
3 oil, IR (film) 761, 907, 1013, 1038, 1208, 1252, 1435, 1719, 2937, 2963
CH
3
CH(CH
3 2
C
2
H
5 oil, IR (film) 761, 902, 922, 1039, 1208, 1252, 1435, 1719, 2934, 6 CH 3
CH(CH
3 2 n-C 3
H
7 oil, IR (film) 924, 984, 1017, 10-3-7, 1208, 1252, 1435, 1719, 2934, 2964 7 C 2
H
5 n-C 3
H
7
CH
3 oil, IR (film) 873, 956, 1018, 1050, 1207, 1252, 1436, 1719, 2938, 8 C 2
H
5 n-C 3
H
7
C
2
H
5 oil, IR (film) 897, 914, 959, 1019, 1049, 1252, 1435, 1720, 2937, 9 C 2
H
5 n-C 3
H
7
CH
2 CmCH oil, IR (film) 870, 956, 1009, 1040, 1208, 1254, 1435, 1717, 2120, 2962
CH
3 CrnCC 6
H
5
CH
3 1 H NMR (CDCl 3 1.61 (d,3H); 2.09 3.69 (s,3H); 4.09 5.13 (s,2H); (m,1OH) ppm
T~
I
M
0050/46043 Table I.B 311 NOCHi 2
C=NOCH
3 CO0 2
CH
3 1No. R 2
R
3 R4Dt 1 CH 3
C
2
H
5 n-C 3
H
7 Oil, IR (film) 958, 989, 1021, 1047, 1069, 1218, 1437, 1729, 2968 152 CH 3
C
2 HS i-C 3
H
7 m.p. 58-600C 3 CH 3
C
2
H
5 n-C 4
H
9 oil, IR (film) 880, 959, 1021, 1070, 1219, 1437, 1730, 2939, 4 CH 3
C
2
H
5 prop-1-en-3-yl IR (KBr) 774, 895, 958, 1011, 1028, 1068, 1303, 1739, 2925
CH
3
C
2
H
5 prop-1-yn-3-yl m.p. 85-88 0
C
6 CH 3
C
2
H
5 3-methyl-but-2-e oil, IR (film) n-883, 958, 1020, 1070, 1219, 1438, 1729, 2939 7 CH 3 CH (CH 3 2
CH
3 m.p. 94-950C 8 CH 3 CH (CH 3 2
C
2
H
5 m.p. 68-710C 9 CH 3 CH (CH 3 2 n-C 3
H
7 m.p. 48-490C 10 CH 3
CH(CH
3 2 i-C 3
H
7 m.p. 58-610C 11 CH 3 CH (CH 3 2 n-C 4
H
9 m.p. 58-610C 12 CH 3 CH (CH 3 2 prop-1-en-3-yl m.p. 59-61 0
C
13 C 2
H
5 CH (CH 3 2
CH
3 m.p. 62-64 0
C
14 C 2
H
5 CH (CH 3 2
C
2
H
5 m.p. 69-71 0
C
C
2
H
5 n-C 3
H
7
CH
3 oil; IR (film) 872, 957, 1020, 1052, 1070, 1219, 1438, 1730, 2940, 2962 16 C 2
H
5 n-C 3
H
7
C
2
H
5 oil; IR (film) 914, 959, 1020, 1051, 1070, 1219, 1437, 1730, 2972 17 C 2
H
5 n-C 3
H
7 H m.p. 102-1040C 4518 C 2
H
5 n-C 3
H
7 prop-1-en-3-yl oil; IR (film) 914, 959, 1020, 1070, 1219, 1321, 1437, 1730, 2961 7Y 0050/ 46043 312 No. R 2
R
3 R4Data 19 C 2
H
5 n-C 3
H
7 prop-1-yn-3-yl oil; IR (film) 958, 1010, 1044, 1070, 1219, 1321, 1438, 1729, 2940, 2962
C
2
H
5 n-C 3
H
7
CH
2 oil; IR (film) [3-CF 3
-C
4
H
4 958, 1019, 1050, 1072, 1127, 1166, 1201, 1219, 1729, 2940, 2960 21 OH 3
-CH
2 0C 6
H
5
CH
3 m.p. 81-830C 22 OH 3
-CH
2 0C 6
H
5
CH
2
CH
3 m.p. 79-81 0
C
23 OH 3
-CH
2 0C 6
H
5
CH
2 C -CH 1 H N'MR(CDC1 3 b[ppm] 2.04(s,3H), 2.45(m,1H), 3.81(s,3H), 3.99(s,3H), 4.78(s,2H), 4.92(s,2H), 5.03(s,2H), 24 OCH 3 4-F-C 6
H
4
OH
3 M.P. 800C! 0-OH 2
OH
3 4-F-C 6
H
4
CH
2
CH
3 m.p. 85-880C 0-OH 2 26 OH 3 4-F-C 6
H
4
CH
2 C -CH 1 H NMR(CDCl 3 0-CH 2 b[ppm] 2.02(s,3H), 2.47(m,1H), 3.81(s,3H), 4.01(s,3H), 4.77(s,2H), 4.87(s,2H), 5.03(s,2H), 6. 75-7 .40(in, 8H) 27 OH 3 4-Cl-C 6
H
4
OH
3 m.P. 112-1150C -0-OH 2 28 OH 3 4-Cl-C 6
H
4
CH
2
CH
3 m.P. 84-870C -0-CH 2 29 OH 3 4-Cl-C 6
H
4
CH
2 C=-CH 1 H NMR(0D01 3 -0-CH 2 6[ppm] 2.02(s,3H), 2.47(m,1H), 3.81(s,3H), 3.99(s,3H), 4.77(s,2H), 4.88(s,2H), 5.03(s,2H), 6.75-7.45(m,8H)
OH
3
CH
2 -CN OH 3 m.p. 143-14500 31 OH 3
CH
2 -CN C 2
H
5 m.p. 69-730C 32 OH 3
CH
2 -CN CH 2 CsCH oil 33 OH 3
CH
2 0- OH 3 M.P. 10000 [2-CN-
C
6
H
4 34 OH 3
CH
2 O- C 2
H
5 m.p. 8400 [2-CN-
C
6
H
4
OH
3
CH
2 0- CH 2 CaCH m.p. 120-1240C [2-ON- 0C 6
H
4 36 O 3
CH
2 SCN H 3 oil '.1-f3 0050/46043 is ___313 No. R 2 RR4Data 37 CH 3
CH
2 SCN C 2
H
5 oil 38 CH 3
CH
2 SCN CH 2 CmCH oil 39 CH 3
CH
2
CH
2 C=-CH oil [4-CN-
C
6
H
4
CH
3
CH
2 CqH 5 M.P. 85 0
C
4-CN- 6
H
4 1 41 CH 3
CH
2
CH
3 M.P. 88-920C [4-CN-
C
6
H
4 42 CH 3
CH
2
CH
2 CmCH oil [1-CH 3 3-CF3-Y razol- 5 43 CH 3
CH
2
C
2
H
5 oil
[I-CH
3 3-CF 3
-PY-
razol- 44 CH 3
CH
2
CH
3 oil
[I-CH
3 3-CF 3
-PY-
razol- -yl] 45 CH 3
CH
2 SCO- C 2
H
5 oil
NHCH
3 46 CH 3
CH
2 SCO- CH 3 oil
____NHCH
3 [47_ CH 3
C!SC-C
6
H
5
CH
3 mp 0-0 0 0050/46043 Table I.C 314
=NOCH
2
-~N
C=NOCH
3
CONHCH
3 r~ No. IRz Data 1 CH 3
C
2
H
5 fl-C 3
H
7 m.p. 62-630C 2 C 3 C2H5 i-C 3
H
7 o8il,, 9R (filjm) 10 8 1 2 1369, 1526, 1668, 2938, 3340 3 CH 3
C
2
H
5 n-C 4
H
9 oil, IR (film) 880, 961, 979, 1038, 1526, 1668, 2875, 2937f 2960, 3340 4 CE 3
C
2
H
5 prop-i-en- m.p. 63-670C 3 -yl 5 CH 3
C
2
H
5 prop-1-yn- oil, IR (film) 3 -yl 870, 884, 980, 1008, 1038, 1670, 2115, 2939, 3280 6 CH 3 C2H5 3-methyl-but oil, IR (film) -2-en-1-yl 884, 956, 980, 1018, 1038, 1448, 1525, 1671, 2938, 3340 7 CH 3 CH (CH 3 2
CH
3 m.p. 78-790C 8 CH 3 CH (CH 3 2 0 2
H
5 m.p. 64-670C 9 CH 3
CH(CH
3 2 n-C 3
H
7 M.P. 72-740C 10 CE 3
CH(CH
3 2 i-C 3
H
7 m.p. 74-770C 11 CH 3
CH(CH
3 2 n-C 4
H
9 m.p. 68-700C 12 CH 3
CH(CH
3 2 prop-i-en- m.p. 59-620C 3-yl 13 CH 3 CH (CH 3 2 prop-1-yn- m.p. 55-570C 3 -yl 14 C 2
H
5 n-C 3
H
7 CH 3 m.p. 94-960C
C
2
H
5 fl-C 3
H
7 H IR (KBr) 767, 890, 913, 957, 983, 1023, 1035, 1523, 1659, 2970, 3408 16 CH 3
CH=CHCH
3 CH 3 1 H NMR(CDCl 3 8[ppm] 1.8(d,3H), 2.03(s,3H), 2.90(d,3H), 3.96(s,6H), 5.08(s,2H), 6.25 6.50 6.73(s,1H), F.10I-7.50(m,4H)
LI
'L23f_3 %Ll2uI.t1 5 I CH3 m.p. 136-1380C
ICE
3 m.p. 136~1380c 0050/ 46043 315 No. R 2
R
3 R4Data 18 CE 3
CH
2
OC
6
H
5
CH
2
CH
3 M.P. 108-110 0
C
19 CH 3
CH
2
OC
6
H
5
CH
2 -C CH 1 H NMR(CDCl 3 b[PPMJ 2.02(s,3H), 2.46(m,1H), 2.81(d,3H), 3.86(S,3H), 4.78(S,2H), 4.93 5.05(s,2H), 6.69(s,1E), 6.80-7.45 (m,9H)
CH
3
CH
2 CH 2 -C=CH oil 4-C1-C 6
H
4 21 CH 3
CH
2 CH 2
CH
3 m.p. 1050C [4-Cl-C 6
H
4 22 CE 3
CH
2 CH 3 m.p. 1550C [4-Cl-C 6
H
4 23 CH 3
CH
2 CH 2 -C =-CH m.p. 89-900c [4-F-C 6
H
4 24 CE 3
CH
2 CH 2
CH
3 m.p. 1080C [4-F-C 6
H
4
CE
3
CH
2 CE 3 M.P. 153-1560C [4-F-C 6
H
4 26 CH 3
CH
2 CN CH 3 m.p. 114-116 0
C
27 CE 3
CH
2 CN
C
2
H
5 q M.P. 100C 28 CE 3
CH
2 CN
CH
2 -C-=CH oil 29 CE 3
CH
2 CH 3 m.p. 103-106 0
C
[2-CN-C 6
H
4 30 CE 3
CH
2 C 2
H
5 oil [2-CN-C 6
H
4 31 CE 3
CE
2 CH 2 -C=-CH M.P. 108-112 0
C
2-CN-C 6
H
4 1 32 CE 3
CH
2 CH 2 -C -=CH m.p. 97-100 0
C
[4-CN-C 6
H
4 33 CE 3
CH
2 C 2
HE
5 M.P. 118-1200C [4-CN-C 6
H
4 34 CE 3
CH
2 CE 3 [4-CN-C 6
H
4
CE
3
CE
2 CH 2 -C=-CH oil [1-CH 3 -3-CF 3 pyrazol- -y 1 36 CE 3
CH
2 C 2
E
5 oil [1-CH 3 -3-CF 3 pyrazol- 5 -yl] 37 CE 3
CH
2 CE 3 oil 1-CH 3 -3-CF 3 pyrazol- 35p8 ICH 3
JCC-C
6
H
5
C
3 Im.p. 1311330C 0050/46043 Table I.D 316
=NOCH
2 -g
C=CHOCH
3
CO
2
CH
3 NO. R 2 RR4Data 1 CH 3 CH (CH 3 2 prop-i-en- m.p. 58-600C 3 -yl 2 CH 3
CH(CH
3 2 but-1--yn- Oil, IR (film) 3 -yl 925, 950, 1038, 1057, 1111, is 1130, 1256, 1284, 1634, 1710, 2940, 2970, 3290 3 CH 3
CH(CH
3 2 3-methyl-but- m.p. 57-590C 4 CH 3
CH(CH
3 2 prop-1-Yn- m.p. 51-540C 3 -yl 5 C 2
H
5 n-C 3
H
7
CH
3 oil; IR (film) 1019, 1055, 1111, 1130, 1256, 1284, 1635, 1711, 2963 6 C 2
H
5 n-C 3
H
7
CH
2
CH=CH
2 oil; IR (film) 959, 1017, 1036, 1111, 1130, 1256, 1284, 1436, 1635, 2940, 2960 7 C 2
H
5 n-C 3
H
7
CH
2 CnCH oil; IR (film) 956, 1088, 1043, 1111, 1130, 1256, 1284, 1436, 1635, 1710, 2120, 2940, 2960 8 C 2
H
5 n-C 3
H
7
CH
2 oil; IR (film) [3-CF 3
-C
6
H
4 1016, 1074, 1128, 1166, 1192, 1201, 1257, 1330, 1711, 2940, 2960 9 CH 3 CwC-C 6
H
5
CH
3 1 H NMR (CDCl 3 2.10 3.67 (s,3H); 3.79 4.09 (s,3H); 5.20 7.13-7.60 mOH) ppm
CH
3 CaC-C 6
H
5
CH
2 CsCH IH 1NMR (CDCl 3 2.10 2.50 (s,1H); 3.67 3.77 (s,3H); 4.85 5.19 (s,2H); (m,1OH) ppm
Z
0050/46043 317 Table I.E
R
2
NOCH
2
R
4 0NH NOCH2 3
R
3 C=NOCH3
RI
CONH
2 No.
R
2
R
3 R4 Data 1 CH 3
CH(CH
3 2
CH
3 m.p. 99-100oc 2 CH3 C2H5 CH3 m.p. 85-900C Table I.F
R
2 R4
NOCH
2 R 40 N OC (1.6)
C=NOCH
3
R
3
CO
2
H
No.
R
2
R
3
R
4 Data 1 CH 3
C
2
H
5
C
2
H
5 m.p. 78-920C Examples of the action against harmful fungi The fungicidal action of the compounds of the formula I was demonstrated by the following experiments: The active ingredients were formulated as a 20% emulsion in a mixture of 70% by weight of cyclohexanone, 20% by weight of Nekanil® LN (Lutensol® AP6, wetting agent having emulsifying and dispersing action, based on ethoxylated alkylphenols) and 10% by weight of Emulphor® EL (Emulan® EL, emulsifier based on ethoxylated fatty alcohols) and diluted with water to give the desired concentration.
Action against Botrytis cinerea (Gray mold) Disks of green bell peppers were sprayed to drip point with the formulation of the active ingredient. After drying, the fruit disks were sprayed with a spore suspension of the fungus Botrytis cinerea (1.7.106 spores per ml of a 2% strength Biomalz solution) and kept for 4 days at 18 0 C and high atmospheric humidity. Scoring was done visually.
0050/46043 318 In this test, the plants which had been treated with 250 ppm of the compounds according to the invention Nos. I.C/7, I.C/8, I.C/11, I.C/13, I.B/7, I.B/8, I.B/10 and I.B/11 (Table/No.) showed an infection level of 40% or less, while the infection level of the untreated (control) plants was 100%.
In a similar test, the plants which had been treated with 250 ppm of the compounds according to the invention Nos. I.A/I, I.A/4, I.A/8, I.B/3, I.B/7, I.B/8, I.B/10, I.B/11, I.B/12, I.B/16, I.B/18, I.B/21, I.B/22, I.B/23, I.C/1, I.C/4, I.C/7, I.C/8, I.C/10, I.C/11, I.C/12, I.C/13, I.C/16, I.C/17, I.C/18, I.C/19, I.D/1, I.D/2, I.D/3, I.D/5 and I.D/6 (Table/No.) showed an infection level of 40% or less, while the infection level of the untreated (control) plants was 100%.
Action against Erysiphe graminis var. tritici (powdery mildew of wheat) Leaves of wheat seedlings (variety "Fruhgold") were first treated with the aqueous formulation of the active ingredients. After approximately 24 hours, the plants were dusted with spores of powdery mildew of wheat (Erysiphe graminis var. tritici). The plants which had thus been treated were subsequently incubated for 7 days at 20 to 22°C and a relative atmospheric humidity of to 80%. The extent of fungal development was subsequently determined.
In this test, the plants which had been treated with 16 ppm of the compounds according to the invention Nos. I.C/7, I.C/8, I.C/10, I.C/11, I.C/13, I.B/7, I.B/8, I.B/10 and I.B/11 (Table/No.) showed an infection level of 25% or less, while the infection level of the untreated (control) plants was In a similar test, the plants which had been treated with 16 ppm of the compounds according to the invention Nos. I.A/I, I.A/2, I.A/3, I.A/4, I.A/5, I.A/7, I.A/8, I.A/9, I.B/1, I.B/2, I.B/3, I.B/6, I.B/9, I.B/12, I.B/13, I.B/14, I.B/15, I.B/16, I.B/17, I.B/18, I.B/19, I.B/20, I.B/22, I.B/31, I.B/32, I.B/36, I.B/37, I.B/47, I.C/1, I.C/2, I.C/3, I.C/4, I.C/5, I.C/9, I.C/12, I.C/14, I.C/15, I.C/16, I.C/35, I.C/38, I.D/1, I.D/2, I.D/3, I.D/4, I.D/5, I.D/6, I.D/7, I.D/8 und I.F/1 (Table/No.) showed an infection level of 15% or less, while the infection level of the untreated (control) plants was \1'A 1(3 3" 0050/46043 319 Action against Puccinia recondita (leaf rust of wheat) Leaves of wheat seedlings (variety "Kanzler") were dusted with spores of leaf rust (Puccinia recondita). The plants which had thus been treated were incubated for 24 hours at 20 to 22°C and a relative atmospheric humidity of 90 to 95% and subsequently treated with the aqueous formulation of the active ingredient.
After a further 8 days at 20 to 22°C and 65 to 70% relative atmospheric humidity, the extent of fungal development was determined. Scoring was done visually.
In this test, the plants which had been treated with 63 ppm of the compounds according to the invention Nos. I.C/7, I.C/8, I.C/11, I.C/13, I.B/8, I.B/10 and I.B/11 (Table/No.) showed an infection level of 15% or less, while the infection level of the untreated (control) plants was In a similar test, the plants which had been treated with 63 ppm of the compounds according to the invention Nos. I.A/I, I.A/2, I.A/3, I.A/4, I.A/5, I.A/6, I.A/7, I.A/8, I.A/9, I.B/1, I.B/2, I.B/3, I.B/9, I.B/13, I.B/14, I.B/15, I.B/16, I.B/19, I.B/22, I.B/24, I.C/1, I.C/2, I.C/3, I.C/4, I.C/5, I.C/6, I.C/9, I.C/12, I.C/13, I.C/16, I.C/24, I.C/27, I.C/28, I.D/2, I.D/5, I.D/6, I.D/7 and I.D/8 (Table/No.) showed an infection level of 15% or less, while the infection level of the untreated (control) plants was Action against Pyricularia oryzae (rice blast) Rice seedlings (variety: "Tai Nong 67") were sprayed to drip point with the formulation of the active ingredient. After 24 hours, the plants were sprayed with an aqueous spore suspension of the fungus Pyricularia oryzae and kept for 6 days at 22 to 24°C at a relative atmospheric humidity of 95 to 99%. Scoring was done visually.
In this test, the plants which had been treated with 63 ppm of the compounds according to the invention Nos. I.C/7, I.C/8, I.C/11, I.C/13, I.B/7, I.B/8, I.B/10 and I.B/11 (Table/No.) showed an infection level of 5% or less, while the infection level of the untreated (control) plants was In a similar test, the plants which had been treated with 63 ppm of the compounds according to the invention Nos. I.A/I, I.A/2, I.A/4, I.A/5, I.A/6, I.A/7, I.A/8, I.A/9, I.B/1, I.B/2, I.B/3, I.B/4, I.B/5, I.B/6, I.B/9, I.B/12, I.B/13, I.B/14, S.B/16, I.B/17, I.B/18, I.B/19, I.B/20, I.B/24, I.B/26,
-J
0050/46043 320 I.B/31, I.B/36, I.B/37, I.B/38, I.C/1, I.C/2, I.C/3, I.C/4, I.C/6, I.C/9, I.C/12, I.C/13, I.C/14, I.C/15, I.C/16, I.C/21, I.C/23, I.C/27, I.C/28, I.C/35, I.C/36, I.C/37, I.D/1, I.D/2, I.D/3, I.D/5, I.D/6 and I.D/7 (Table/No.) showed an infection level of 15% or less, while the infection level of the untreated (control) plants was Examples of the action against animal pests The action of the compounds of the general formula I against animal pests was demonstrated by the following experiments: The active ingredients were formulated a) as a 0.1% strength solution in acetone or b) as a 10% emulsion in a mixture of 70% by weight of cyclohexanone, 20% by weight of Nekanil® LN (Lutensol® AP6, wetting agent having emulsifying and dispersing action, based on ethoxylated alkylphenols) and 10% by weight of Emulphor® EL (Emulan® EL, emulsifier based on ethoxylated fatty alcohols) and diluted to give the desired concentration, using acetone in the case of a) and water in the case of b).
After the experiments had been concluded, in each case the lowest concentration at which the compounds still caused an 80 to 100% inhibition or mortality in comparison with untreated control experiments [sic] was determined (limit or minimal concentration).
Nephotettix cincticeps (green rice leaf hopper), contact action Filter disks were treated with the aqueous formulation of the active ingredient and subsequently populated with 5 adult leaf hoppers. After 24 hours, the mortality was assessed.
In this test, the limit concentrations of the compounds I.B/7 and were less than 0.4 mg.
In a similar test, the limit concentrations of the compounds I.A/I, I.A/2, I.A/4, I.A/5, I.A/6, I.A/9, I.B/12, I.B/13, I.B/14, I.B/15, I.B/29, I.B/32, I.C/3, I.C/20, I.C/21, I.C/22, I.C/23, I.C/24, I.C/25, I.C/27, I.C/28 and I.C/30 were 0.4 mg and less.
VT 0 c^ 0050/46043 321 Nephotettix cincticeps (green rice leafhopper), contact action, spray experiment Rice plants approximately 8 cm long were treated with the aqueous preparation of the active ingredient and, after drying, populated with 10 adult leafhoppers. After 48 hours, the mortality was determined.
In this test, the limit concentrations of the compounds I.A/I, 2, 3, 5, 6 and I.B/12 were 400 ppm or less.
Prodenia litura (Egyptian cotton leaf worm), contact action The bottom of a test container was wetted with a solution of the active ingredient in acetone and, after the solvent had evaporated, populated with 5 4th instar caterpillars. After 4 hours, the mortality was determined.
In this test, the limit concentration of compound I.C/13 was 0.4 mg.
In a similar test, the limit concentrations of the compounds according to the invention I.A/8, I.B/18, I.D/5, I.D/6 and I.D/7 were 0.4 mg or less.
Aphis fabae (black louse systemic action Severely infested dwarf beans (Vicia faba) were treated with the aqueous formulation of the active ingredient. After 48 hours, the mortality rate was determined.
In this test, the limit concentrations of the compounds I.B/8, and I.C/8 were from 100 to 400 ppm.
In a similar test, the limit concentrations of the compounds according to the invention I.A/I, I.A/2, I.A/5, I.A/6, I.B/25 and I.E/1 were 400 ppm or less.
Tetranychus urticae (spider mite), contact action Severely infested dwarf beans in pots which had produced the second consecutive pair of leaves were treated with the aqueous formulation of the active ingredient. After 5 days in the greenhouse, the result of the control measure was determined by means of a stereomicroscope.
0050/46043 322 In this test, the limit concentration of the compound I.C/13 was less than 100 ppm.
In a similar test, the limit concentrations of the compounds according to the invention I.A/7, I.A/8, I.A/9, I.B/15, I.B/16, I.B/18, I.B/19, I.B/20, I.C120, I.C/23, I.D/4, I.D/5, I.D/6, I.D17 and I.D18 were 400 ppm or less.
77T

Claims (15)

1. A phenylacetic acid derivative of the formula I R4ONaiC(R 3 )-C(R 2 )uNOCH 2 (I) OC-Y-R where the substituents and the index have the following meanings: X is NOCH1 3 CHOCH 3 or CHCH 3 Y is NRorO0; 00 R, Rlare hydrogen or C 1 C-alkyl; R2 is hydrogen, Cl-C 6 -alkyl, Cl-C 4 -haloalkyl or C 3 -C 6 -cycloalkyl; :R3 is C 2 -C 6 -alkenyl; R4 is hydrogen, 0 C 1 -Cl-alkyl, C 3 -C 6 -CYCloalkyl, C 2 -Clo-alkenyl, C 2 -Cl 0 0alkynyl, Cl-C 1 -alkylcarbonyl, C2-Clo-alkenylcarbonyl, C 3 -Cl-alkynylcarbonyl or Cl-C 1 -alkylsulfonyl, it being possible for these radicals to be partially or fully halogenated or to have attached to them one to three of the following groups: cyano, nitro, hydroxyl, mercato, amino, carboxyl, aminocarbonyl, aminothiocarbonyl, (tenext page is page 324 which is intentionally blank) 324 (THIS PAGE IS INTENTIONALLY BLANK) 00 0 000 0 0000 *00*00 0 00 0 0 0 0000 0 0 0 0 0000 0000 0* 00 00 0000 00 0* 00 0* 00 00 00 0 000 00 0 0e 00 0 0050/ 46043 325 halogen, Ci-C 6 -alkyl, CI-C 6 -haloalkyl, C1-C6-alkyl- sulfonyl, Cj-C 6 -alkylsulfoxyl, Cl-C 6 -alkoxy, C1-C6-haloalkoxy, C1-C6-alkoxycarbonyl, Cl-C6-alkylthio, Ci1-C6-alkyl amino, di-Ci--C 6 -alkylamino, Cl-C6-alkylamino- carbonyl, di-C1-C6-alkylaminocarbonyl, C1-C6-alkylaminothiocarbonyl, di-C1-C6--alkylaminothio- carbonyl, C2-C 6 -alkenyl, C2-C 6 -alkenyloxy, C3C6-cycloalkyl, C3-C6--cycloalkyloxy, heterocyclyl, heterocyclyloxy, benzyl, benzyloxy, aryl, aryloxy, arylthio, hetaryl, hetaryloxy and hetaryithic, it being possible for the cyclic groups, in turn, to be partially or fully halogenated or to have attached to them one to three of the following groups: cyano, nitro, hydroxyl, mercapto, amino, carboxyl, is aminocarbonyl, aminothiocarbonyl, halogen, CI-C 6 -alkyl, CI-C 6 -haloalkyl, C-C6-alkylsulfonyl, CI-C 6 -alkyl- sulfoxyl, C3-C6-cycloalkyl, CI-C 6 -alkoxy, Cl-C6-halo- alkoxy, CI-C6-alkyloxycarbonyl, C1-C6-alkylthio, C 1-C6-alkylamino, di-C 1-C6-alkylalnino, C 1-C6-alkylamino- carbonyl, di-C1-C6-alkylaminocarbonyl, C1-C6-alkylaminothiocarbonyl, di-Ci-C6-alkylamino- thiocarbonyl, C2-C6-alkenyl, C2-C6-alkenyloxy, benzyl, benzyloxy, aryl, aryloxy, arylthio, hetaryl, hetaryloxy, hetarylthio or C(=NORa)-A,-Rb; aryl, arylcarbonyl, arylsulfonyl, hetaryl, hetaryl- carbonyl or hetarylsulfonyl, it being possible for these radicals to be partially or fully halogenated or to have attached to them one to three of the following groups: cyano, nitro, hydroxyl, mercapto, amino, carboxyl, aminocarbonyl, aminothiocarbonyl, halogen, Cl-C 6 -alkyl, Cl-C 6 -haloalkyl, Cl-C6-alkylcarbonyl, C1-C6-alkylsulfonyl, Ca-C6-alkylsulfoxyl, C3-C 6 -cyclo- alkyl, CI-C6-alkoxy, Cl-C6-haloalkoxy, Cl-C6-alkyloxy- carbonyl, Cl-C6-alkylthio, Cl-C6-alkylamino, di-Ci-C 6 -alkylamino, C1-C6-alkylaminocarbonyl, di-Cl-C 6 alkylaminocarbonyl, Cl-C6-alkylaxninothiocarbonyl, di-Cl-C6-alkylaminothiocarbonyl, C2-C6-alkenyl, C2-C6-alkenyloxy, benzyl, benzyloxy, aryl, aryloxy, hetaryl, hetaryloxy or C(=NORa)-An-~Rb; where A is oxygen, sulfur or nitrogen and the nitrogen having attached to it hydrogen or Cl-C 6 -alkyl; 326 n is 0 or 1; Ra is hydrogen or C1-C 6 -alkyl and Rb is hydrogen or Cl-C 6 -alkyl, or a salt thereof.
2. A phenylacetic acid derivative of the formula I according to claim 1 where R2 is hydrogen, Cl-C 6 -alkyl or C3-C6-cycloalkyl; and the other substituents have the meanings shown in claim 1.
3. A phenylacetic acid derivative of the formula I according to claim 1 where R3 is vinyl, allyl, prop-1-enyl, 2-methylprop-l-enyl or iso-propenyl and the V. other substituents have the meanings shown in claim 1.
4. A compound of the formula I as claimed in claim 1 where X is NOCH 3 Y is NH and R1 is methyl. A compound of the formula I as claimed in claim 1 where R1 is methyl.
6. A process for the preparation of the compounds of the formula I as claimed in claim 1, which includes reacting a benzyl derivative of the formula II L-CHz o c x (li) C=X O=C-Y-R I where L1 is a nucleophilically exchangeable leaving group in a manner known per se with a hydroxyimine of the formula III R 4 0N=C(R 3 =NOH (III). 327
7. A process for the preparation of the compounds of the formula I as claimed in claim 1, which includes reacting a benzyl derivative of the formula II as defined in claim 6 in a manner known per se with a dihydroxyimine of the formula IV HON=C(R 3 )-C(R 2 )=NOH (IV) to give a compound of the formula V HON=C(R 3 )-C(R)=NOCH 2 C=X I O=C-Y-R 1 and subsequently reacting V with a compound of the formula VI R4-L2 (VI) where L2 is a nucleophilically exchangeable leaving group, to give I.
8. A process for the preparation of the compounds of the formula I as claimed in claim 1, which includes reacting a benzyl derivative of the formula II as defined in claim 6 in a manner known per se with a carbonylhydroxyimine of the formula VII 0 O=C(R3)-C(R2)=NOH (VII) to give a compound of the formula VIII O=C(R 3 )-C(R 2 )=NOCH 2 (VIII) C=X O=C-Y-R 1 and subsequently reacting VIII either 328 a) first with hydroxylamine or salt thereof and then with a compound of the formula VI (R4-L2) as defined in claim 7 or b) with a hydroxylamine or a hydroxylammonium salt of the formula IXa or IXb R 4 -ONH 2 RON lxa R4-ON O IXb where Qe is the anion of an acid, to give I.
9. A compound of the general formula V as defined in claim 7. The use of a compound of the general formula V as defined in claim 7 as an intermediate.
11. A compound of the general formula VIII as defined in claim 8.
12. The use of a compound of the general formula VIII as defined in claim 8 as an intermediate.
13. A composition against animal pests or harmful fungi, including customary additives and an effective amount of a compound of the formula I as claimed in claim 1.
14. A method of controlling animal pests or harmful fungi, which includes treating the pests or harmful fungi, their environment, or the plants, areas, materials or spaces to be kept free from them with an effective amount of a compound of the formula I as claimed in claim 1. The use of the compounds I as claimed in claim 1 for the preparation of compositions against animal pests or harmful fungi. 329
16. The use of the compounds I as claimed in claim 1 for controlling animal pests or harmful fungi.
17. A phenylacetic acid derivative according to formula I of claim 1 and as herein described with reference to the tables and examples.
18. A process according to claim 6 and as herein described with reference to the examples. DATED this 22nd day of September 1999 BASF AKTIENGESELLSCHAFT WATERMARK PATENT TRADEMARK ATTORNEYS 290 BURWOOD ROAD HAWTHORN VICTORIA 3122 S AUSTRALIA LCG:CLR:VRH DOC 28 AU6614796.WPC 9 o i *o* v *o
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DE1995141382 DE19541382A1 (en) 1995-11-07 1995-11-07 New (hydroximino-alkylidene)-imino-oxymethyl-phenyl:acetic acid derivs.
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