AU6849500A - Cationic lipid compounds and use thereof for transferring negatively charged substances of therapeutic interest - Google Patents

Cationic lipid compounds and use thereof for transferring negatively charged substances of therapeutic interest

Info

Publication number
AU6849500A
AU6849500A AU68495/00A AU6849500A AU6849500A AU 6849500 A AU6849500 A AU 6849500A AU 68495/00 A AU68495/00 A AU 68495/00A AU 6849500 A AU6849500 A AU 6849500A AU 6849500 A AU6849500 A AU 6849500A
Authority
AU
Australia
Prior art keywords
negatively charged
cationic lipid
lipid compounds
therapeutic interest
charged substances
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU68495/00A
Inventor
Xuan An Cao
Robert Coudert
Regine Naejus
Eliane Taillandier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite Sorbonne Paris Nord Paris 13
Original Assignee
Universite Sorbonne Paris Nord Paris 13
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite Sorbonne Paris Nord Paris 13 filed Critical Universite Sorbonne Paris Nord Paris 13
Publication of AU6849500A publication Critical patent/AU6849500A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • C07J41/0061Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives one of the carbon atoms being part of an amide group

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
AU68495/00A 1999-08-04 2000-08-03 Cationic lipid compounds and use thereof for transferring negatively charged substances of therapeutic interest Abandoned AU6849500A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9910141 1999-08-04
FR9910141A FR2797188A1 (en) 1999-08-04 1999-08-04 CATIONIC LIPID COMPOUNDS AND THEIR USE FOR THE TRANSFER OF NEGATIVELY CHARGED SUBSTANCES OF THERAPEUTIC INTEREST
PCT/FR2000/002234 WO2001011068A2 (en) 1999-08-04 2000-08-03 Cationic lipid compounds and use thereof for transferring negatively charged substances of therapeutic interest

Publications (1)

Publication Number Publication Date
AU6849500A true AU6849500A (en) 2001-03-05

Family

ID=9548888

Family Applications (1)

Application Number Title Priority Date Filing Date
AU68495/00A Abandoned AU6849500A (en) 1999-08-04 2000-08-03 Cationic lipid compounds and use thereof for transferring negatively charged substances of therapeutic interest

Country Status (5)

Country Link
EP (1) EP1218033A2 (en)
AU (1) AU6849500A (en)
CA (1) CA2381224A1 (en)
FR (1) FR2797188A1 (en)
WO (1) WO2001011068A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4423107A1 (en) * 2021-10-29 2024-09-04 ModernaTX, Inc. Lipid amines

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5283185A (en) * 1991-08-28 1994-02-01 University Of Tennessee Research Corporation Method for delivering nucleic acids into cells
FR2726764B1 (en) * 1994-11-14 1997-01-31 Pasteur Merieux Serums Vacc ADJUVANT FOR VACCINE COMPOSITION
AU2911197A (en) * 1996-05-24 1998-01-05 Imperial College Of Science, Technology And Medicine Polycationic sterol derivatives as transfection agents
EP0910343A1 (en) * 1996-07-03 1999-04-28 University Of Pittsburgh Emulsion formulations for hydrophilic active agents
DE19631189A1 (en) * 1996-08-02 1998-02-05 Max Delbrueck Centrum Novel cationic amphiphiles for liposomal gene transfer

Also Published As

Publication number Publication date
EP1218033A2 (en) 2002-07-03
WO2001011068A3 (en) 2002-05-02
CA2381224A1 (en) 2001-02-15
WO2001011068A2 (en) 2001-02-15
FR2797188A1 (en) 2001-02-09

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase