AU684631B2 - Improved methods for transplantation using modified cells and T cell inhibitory agents - Google Patents

Improved methods for transplantation using modified cells and T cell inhibitory agents

Info

Publication number
AU684631B2
AU684631B2 AU22021/95A AU2202195A AU684631B2 AU 684631 B2 AU684631 B2 AU 684631B2 AU 22021/95 A AU22021/95 A AU 22021/95A AU 2202195 A AU2202195 A AU 2202195A AU 684631 B2 AU684631 B2 AU 684631B2
Authority
AU
Australia
Prior art keywords
cell
antigen
cells
subject
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU22021/95A
Other languages
English (en)
Other versions
AU2202195A (en
Inventor
Thomas Fraser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Diacrin Inc
Original Assignee
Diacrin Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diacrin Inc filed Critical Diacrin Inc
Publication of AU2202195A publication Critical patent/AU2202195A/en
Application granted granted Critical
Publication of AU684631B2 publication Critical patent/AU684631B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2833—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/39—Pancreas; Islets of Langerhans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Physiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Nutrition Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU22021/95A 1994-03-31 1995-03-30 Improved methods for transplantation using modified cells and T cell inhibitory agents Ceased AU684631B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22072494A 1994-03-31 1994-03-31
US220724 1994-03-31
PCT/US1995/003959 WO1995026740A1 (fr) 1994-03-31 1995-03-30 Procedes ameliores de transplantation a l'aide de cellules modifiees et d'agents inhibiteurs de lymphocytes t

Publications (2)

Publication Number Publication Date
AU2202195A AU2202195A (en) 1995-10-23
AU684631B2 true AU684631B2 (en) 1997-12-18

Family

ID=22824688

Family Applications (1)

Application Number Title Priority Date Filing Date
AU22021/95A Ceased AU684631B2 (en) 1994-03-31 1995-03-30 Improved methods for transplantation using modified cells and T cell inhibitory agents

Country Status (4)

Country Link
EP (1) EP0752868A1 (fr)
AU (1) AU684631B2 (fr)
CA (1) CA2186527A1 (fr)
WO (1) WO1995026740A1 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996037602A1 (fr) * 1995-05-26 1996-11-28 Diacrin, Inc. Hepatocytes porcins a utiliser dans le traitement de troubles caracterises par une fonction hepatique insuffisante
US6046379A (en) * 1995-06-07 2000-04-04 Stone; Kevin R. Meniscal xenografts
US5913900A (en) * 1995-06-07 1999-06-22 Corsscart, Inc. Substantially native meniscal cartilage heterografts
US5865849A (en) * 1995-06-07 1999-02-02 Crosscart, Inc. Meniscal heterografts
US5984858A (en) * 1995-06-07 1999-11-16 Crosscart, Inc. Meniscal xenografts
US6231608B1 (en) 1995-06-07 2001-05-15 Crosscart, Inc. Aldehyde and glycosidase-treated soft and bone tissue xenografts
US6110206A (en) * 1995-09-15 2000-08-29 Crosscart, Inc. Anterior cruciate ligament xenografts
US5944755A (en) * 1995-09-15 1999-08-31 Crosscart, Inc. Articular cartilage xenografts
US5782915A (en) * 1995-09-15 1998-07-21 Stone; Kevin R. Articular cartilage heterografts
US6210440B1 (en) 1995-09-15 2001-04-03 Kevin R. Stone Anterior cruciate ligament xenografts
US5902338A (en) * 1995-09-15 1999-05-11 Crosscart, Inc. Anterior cruciate ligament heterograft
US6049025A (en) * 1995-09-15 2000-04-11 Stone; Kevin R. Articular cartilage xenografts
CA2279978A1 (fr) * 1996-02-01 1997-08-07 Si-Myung Byun Modulation antigenique de cellules
US8007784B1 (en) 1996-06-27 2011-08-30 Albany Medical College Antigenic modulation of cells
DE69841058D1 (de) 1997-11-14 2009-09-24 Gen Hospital Corp Behandlung von hämatologischen störungen
JP2002505144A (ja) 1998-03-06 2002-02-19 クロスカート インコーポレイテッド 軟組織異種移植片
US6383732B1 (en) 1999-02-11 2002-05-07 Crosscart, Inc. Method of preparing xenograft heart valves
US6972041B1 (en) 1998-03-16 2005-12-06 Crosscart, Inc. Bone xenografts
WO2000018414A1 (fr) * 1998-09-29 2000-04-06 Diacrin, Inc. Transplantation de cellules neuronales pour le traitement des lesions ischemiques dues a une attaque
US6444205B2 (en) * 1998-09-30 2002-09-03 Diacrin, Inc. Transplantation of neural cells for the treatment of chronic pain or spasticity
US6267786B1 (en) 1999-02-11 2001-07-31 Crosscart, Inc. Proteoglycan-reduced soft tissue xenografts

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5962694A (en) * 1992-12-31 1994-08-15 Exemplar Corporation Producing cells for transplantation to reduce host rejection and resulting cells

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985000954A1 (fr) * 1983-09-01 1985-03-14 The Trustees Of Columbia University In The City Of Procedes de developpement de l'acceptation d'organes et tissus greffes
US5283058A (en) * 1990-08-30 1994-02-01 The General Hospital Corporation Methods for inhibiting rejection of transplanted tissue

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5962694A (en) * 1992-12-31 1994-08-15 Exemplar Corporation Producing cells for transplantation to reduce host rejection and resulting cells

Also Published As

Publication number Publication date
CA2186527A1 (fr) 1995-10-12
EP0752868A1 (fr) 1997-01-15
WO1995026740A1 (fr) 1995-10-12
AU2202195A (en) 1995-10-23

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired