AU680450B2 - Support for the synthesis of modular polymers - Google Patents

Support for the synthesis of modular polymers

Info

Publication number
AU680450B2
AU680450B2 AU53315/94A AU5331594A AU680450B2 AU 680450 B2 AU680450 B2 AU 680450B2 AU 53315/94 A AU53315/94 A AU 53315/94A AU 5331594 A AU5331594 A AU 5331594A AU 680450 B2 AU680450 B2 AU 680450B2
Authority
AU
Australia
Prior art keywords
synthesis
support
modular
peptide
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU53315/94A
Other languages
English (en)
Other versions
AU5331594A (en
Inventor
Andrew M Bray
H. Mario Geysen
N. Joe Maeji
Robert M Valerio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mimotopes Pty Ltd
Original Assignee
Chiron Mimotopes Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Mimotopes Pty Ltd filed Critical Chiron Mimotopes Pty Ltd
Publication of AU5331594A publication Critical patent/AU5331594A/en
Application granted granted Critical
Publication of AU680450B2 publication Critical patent/AU680450B2/en
Assigned to MITOKOR reassignment MITOKOR Alteration of Name(s) in Register under S187 Assignors: CHIRON MIMOTOPES PTY LTD
Assigned to MIMOTOPES PTY LTD reassignment MIMOTOPES PTY LTD Alteration of Name(s) in Register under S187 Assignors: MITOKOR
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/045—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers using devices to improve synthesis, e.g. reactors, special vessels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00306—Reactor vessels in a multiple arrangement
    • B01J2219/00322—Reactor vessels in a multiple arrangement the individual reactor vessels being arranged serially in stacks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00504—Pins
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00504—Pins
    • B01J2219/00506—Pins with removable crowns
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00545—Colours
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00554—Physical means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00563—Magnetic means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00725—Peptides
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Graft Or Block Polymers (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU53315/94A 1992-11-06 1993-10-25 Support for the synthesis of modular polymers Ceased AU680450B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97275592A 1992-11-06 1992-11-06
US972755 1992-11-06
PCT/AU1993/000546 WO1994011388A1 (en) 1992-11-06 1993-10-25 Support for the synthesis of modular polymers

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU22806/97A Division AU2280697A (en) 1992-11-06 1997-05-16 Support for the synthesis of modular polymers

Publications (2)

Publication Number Publication Date
AU5331594A AU5331594A (en) 1994-06-08
AU680450B2 true AU680450B2 (en) 1997-07-31

Family

ID=25520079

Family Applications (2)

Application Number Title Priority Date Filing Date
AU53315/94A Ceased AU680450B2 (en) 1992-11-06 1993-10-25 Support for the synthesis of modular polymers
AU22806/97A Abandoned AU2280697A (en) 1992-11-06 1997-05-16 Support for the synthesis of modular polymers

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU22806/97A Abandoned AU2280697A (en) 1992-11-06 1997-05-16 Support for the synthesis of modular polymers

Country Status (7)

Country Link
EP (1) EP0672049A4 (ja)
JP (1) JPH08505604A (ja)
AU (2) AU680450B2 (ja)
CA (1) CA2148591A1 (ja)
HU (1) HUT73150A (ja)
NZ (1) NZ257077A (ja)
WO (1) WO1994011388A1 (ja)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA46707C2 (uk) 1993-05-10 2002-06-17 Чірон Корпорейшн Спосіб типування вірусу гепатиту с (варіанти), набір поліпептидів (варіанти), реагент, що включає комбінацію поліпептидів, які містять типоспецифічні епітопи гепатиту с (варіанти)
US6171555B1 (en) 1995-04-17 2001-01-09 Ontogen Corporation Reaction block docking station
US5609826A (en) * 1995-04-17 1997-03-11 Ontogen Corporation Methods and apparatus for the generation of chemical libraries
US6100026A (en) * 1995-04-25 2000-08-08 Irori Matrices with memories and uses thereof
US5961923A (en) * 1995-04-25 1999-10-05 Irori Matrices with memories and uses thereof
US6284459B1 (en) 1995-04-25 2001-09-04 Discovery Partners International Solid support matrices with memories and combinatorial libraries therefrom
GB9521943D0 (en) * 1995-10-26 1996-01-03 Univ Hertfordshire Coded particles for process sequence tracking in combinatorial compound library preparation
US6660233B1 (en) 1996-01-16 2003-12-09 Beckman Coulter, Inc. Analytical biochemistry system with robotically carried bioarray
US6265219B1 (en) 1996-10-30 2001-07-24 Mitokor Transponder tagging of constituents used in compound synthesis
JP2002513403A (ja) * 1997-02-26 2002-05-08 イーライ・リリー・アンド・カンパニー 医薬品化合物を製造するための選択的なエポキシ化方法
AU736776B2 (en) 1997-07-22 2001-08-02 Qiagen Genomics, Inc. Apparatus and methods for arraying solution onto a solid support
US6362009B1 (en) 1997-11-21 2002-03-26 Merck & Co., Inc. Solid phase synthesis of heterocycles
BR9814604A (pt) * 1997-12-31 2000-10-17 Qiagen Genomics Inc "ponteiras em fase sólida e seus usos"
US6541211B1 (en) * 1998-05-20 2003-04-01 Selectide Corporation Apparatus and method for synthesizing combinational libraries
US7584240B2 (en) 2001-11-07 2009-09-01 Genvault Corporation Automated biological sample archive for storage, retrieval and analysis of large numbers of samples for remote clients
US7142987B2 (en) * 2001-11-07 2006-11-28 Genvault Corporation Apparatus, system, and method of archival and retrieval of samples
US7718442B2 (en) 2002-11-22 2010-05-18 Genvault Corporation Sealed sample storage element system and method
JP2008509226A (ja) 2004-05-24 2008-03-27 ジェンボールト コーポレイション 回収可能な形式での安定なタンパク質保管および安定な核酸保管
US8283165B2 (en) 2008-09-12 2012-10-09 Genvault Corporation Matrices and media for storage and stabilization of biomolecules

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6359390A (en) * 1989-09-15 1991-04-18 Coselco Mimotopes Pty Ltd Solid surface for peptide synthesis

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60500535A (ja) * 1982-12-29 1985-04-18 サザン　イリノイ　ユニバ−シテイ　フアウンデイシヨン ポリヌクレオチドの製造方法
AU576750B2 (en) * 1983-03-08 1988-09-08 Chiron Mimotopes Pty Ltd Method of determining antigenically active amino acid sequences
US4515920A (en) * 1984-04-30 1985-05-07 The Rockefeller University Synthesis of peptides and proteins
CA1304916C (en) * 1984-10-18 1992-07-14 Wilhelm Bannwarth Apparatus for the parallel performance of a plurality of chemical reaction sequences
IL84939A (en) * 1987-01-06 1991-05-12 Baylor College Medicine Chemically inert wafer for synthesizing biopolymers
US4794150A (en) * 1987-03-11 1988-12-27 Samuel Steel Synthesis of peptide analogs
CA2047191A1 (en) * 1989-02-17 1990-08-18 Hendrik M. Geysen Method for the use and synthesis of peptides
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
DE3935572A1 (de) * 1989-10-25 1991-05-02 Biotechnolog Forschung Gmbh Verfahren zur peptidsynthese und traeger dafuer

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6359390A (en) * 1989-09-15 1991-04-18 Coselco Mimotopes Pty Ltd Solid surface for peptide synthesis

Also Published As

Publication number Publication date
WO1994011388A1 (en) 1994-05-26
EP0672049A1 (en) 1995-09-20
JPH08505604A (ja) 1996-06-18
CA2148591A1 (en) 1994-05-26
AU5331594A (en) 1994-06-08
AU2280697A (en) 1997-08-28
HUT73150A (en) 1996-06-28
NZ257077A (en) 1997-05-26
EP0672049A4 (en) 1997-10-15
HU9501322D0 (en) 1995-06-28

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Legal Events

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Owner name: MIMOTOPES PTY. LTD.

Free format text: FORMER OWNER WAS: MITOKOR