AU642980B2 - Ultilization of enzymes - Google Patents

Ultilization of enzymes

Info

Publication number
AU642980B2
AU642980B2 AU72997/91A AU7299791A AU642980B2 AU 642980 B2 AU642980 B2 AU 642980B2 AU 72997/91 A AU72997/91 A AU 72997/91A AU 7299791 A AU7299791 A AU 7299791A AU 642980 B2 AU642980 B2 AU 642980B2
Authority
AU
Australia
Prior art keywords
enzymes
antibody
enzyme
target
product according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU72997/91A
Other languages
English (en)
Other versions
AU7299791A (en
Inventor
Thomas Stewart Beggs
Paul James Davis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Givaudan Nederland Services BV
Original Assignee
Unilever PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909006329A external-priority patent/GB9006329D0/en
Priority claimed from GB909021671A external-priority patent/GB9021671D0/en
Application filed by Unilever PLC filed Critical Unilever PLC
Publication of AU7299791A publication Critical patent/AU7299791A/en
Application granted granted Critical
Publication of AU642980B2 publication Critical patent/AU642980B2/en
Assigned to QUEST INTERNATIONAL B.V. reassignment QUEST INTERNATIONAL B.V. Alteration of Name(s) in Register under S187 Assignors: UNILEVER PLC
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A61K47/6815—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6883—Polymer-drug antibody conjugates, e.g. mitomycin-dextran-Ab; DNA-polylysine-antibody complex or conjugate used for therapy
    • A61K47/6885—Polymer-drug antibody conjugates, e.g. mitomycin-dextran-Ab; DNA-polylysine-antibody complex or conjugate used for therapy the conjugate or the polymer being a starburst, a dendrimer, a cascade
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/94—Involves covalent bonding to the substrate

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Birds (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Biotechnology (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Cosmetics (AREA)
  • Detergent Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
AU72997/91A 1990-03-21 1991-03-18 Ultilization of enzymes Ceased AU642980B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB909006329A GB9006329D0 (en) 1990-03-21 1990-03-21 Cell killing
GB9006329 1990-03-21
GB909021671A GB9021671D0 (en) 1990-10-05 1990-10-05 Delivery of agents
GB9021671 1990-10-05

Publications (2)

Publication Number Publication Date
AU7299791A AU7299791A (en) 1991-10-03
AU642980B2 true AU642980B2 (en) 1993-11-04

Family

ID=26296816

Family Applications (1)

Application Number Title Priority Date Filing Date
AU72997/91A Ceased AU642980B2 (en) 1990-03-21 1991-03-18 Ultilization of enzymes

Country Status (8)

Country Link
EP (1) EP0451972B1 (show.php)
JP (1) JPH0584073A (show.php)
AT (1) ATE138579T1 (show.php)
AU (1) AU642980B2 (show.php)
CA (1) CA2038579C (show.php)
DE (1) DE69119817T2 (show.php)
ES (1) ES2088463T3 (show.php)
IN (1) IN172887B (show.php)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU680407B2 (en) * 1992-03-06 1997-07-31 Creagen, Inc. Pathogen-targeted biocatalyst

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL9401048A (nl) * 1994-03-31 1995-11-01 Stichting Scheikundig Onderzoe Haloperoxidasen.
US5665333A (en) * 1995-01-17 1997-09-09 Homola; Andrew M. Methods, compositions, and dental delivery systems for the protection of the surfaces of teeth
AU1194697A (en) * 1995-12-21 1997-07-17 Quest International B.V. Particle compositions
US5961958A (en) * 1996-07-16 1999-10-05 Four Star Partners Methods, compositions, and dental delivery systems for the protection of the surfaces of teeth
US5972355A (en) * 1997-09-30 1999-10-26 E-L Management Corp. Stable compositions containing biologically active components
US5871714A (en) * 1997-10-16 1999-02-16 Pharmacal Biotechnologies, Inc. Compositions for controlling bacterial colonization
AU3703100A (en) 1999-02-22 2000-09-14 Georgetown University Antibody fragment-targeted immunoliposomes for systemic gene delivery
US9034329B2 (en) 1999-02-22 2015-05-19 Georgetown University Preparation of antibody or an antibody fragment-targeted immunoliposomes for systemic administration of therapeutic or diagnostic agents and uses thereof
US7780882B2 (en) 1999-02-22 2010-08-24 Georgetown University Simplified and improved method for preparing an antibody or an antibody fragment targeted immunoliposome for systemic administration of a therapeutic or diagnostic agent
DE60019309T2 (de) * 1999-09-16 2005-09-22 Unilever Plc Abgabesystem für ein mittel gegen schuppen
FR2803199B1 (fr) 1999-12-29 2002-05-10 Jean Dominique Dana Procede de transformation des sucres alimentaires cariogenes en produits neutres acariogenes ou cariostatiques et composition pour la mise en oeuvre
ATE407684T1 (de) * 2001-04-02 2008-09-15 Univ Georgetown Vereinfachtes und verbessertes verfahren zur herstellung eines antikörper- oder antikörperfragment-targeted immunoliposoms oder polyplex für die systemische verabreichung eines therapeutischen oder diagnostischen mittels
BRPI0617481A2 (pt) * 2005-10-21 2011-07-26 Danisco composiÇço que compreende um sistema enzimÁtico acoplado
EP2023897A4 (en) 2006-05-15 2013-04-03 Univ Georgetown PREPARATION OF ANTIBODY OR ANTIBODY FRAGMENT-TUNED IMMUNOLIPOSOMES FOR SYSTEMIC ADMINISTRATION OF THERAPEUTIC OR DIAGNOSTIC ACTIVITIES AND USES THEREOF
ES2784495T3 (es) 2010-12-20 2020-09-28 Dupont Us Holding Llc Generación enzimática de perácidos para su uso en productos para el cuidado bucodental

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7299691A (en) * 1990-03-21 1991-10-03 Quest International B.V. Utilization and delivery of enzymes
AU5544090A (en) * 1990-04-26 1991-11-11 Ringdal Patenter A/S Activating unit for weapon

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4578265A (en) * 1981-08-13 1986-03-25 Laclede Professional Products, Inc. Di-enzymatic dentifrice
ES2054678T5 (es) * 1986-08-18 1997-09-16 Dow Chemical Co Conjugados estrella.
WO1990003185A1 (en) * 1988-09-28 1990-04-05 Ideon Corporation Combination enzyme immunotherapeutics
AU5546090A (en) * 1989-06-30 1991-01-17 Brunswick Corporation Antibody-lactate oxidase conjugates
FR2651433B1 (fr) * 1989-09-07 1994-01-14 Dominique Dana Complexe enzymatique a activite sur le tartre et la carie dentaire.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7299691A (en) * 1990-03-21 1991-10-03 Quest International B.V. Utilization and delivery of enzymes
AU5544090A (en) * 1990-04-26 1991-11-11 Ringdal Patenter A/S Activating unit for weapon

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU680407B2 (en) * 1992-03-06 1997-07-31 Creagen, Inc. Pathogen-targeted biocatalyst

Also Published As

Publication number Publication date
EP0451972A1 (en) 1991-10-16
DE69119817T2 (de) 1996-10-31
CA2038579A1 (en) 1991-09-22
CA2038579C (en) 1998-06-23
ES2088463T3 (es) 1996-08-16
IN172887B (show.php) 1993-12-25
ATE138579T1 (de) 1996-06-15
DE69119817D1 (de) 1996-07-04
EP0451972B1 (en) 1996-05-29
AU7299791A (en) 1991-10-03
JPH0584073A (ja) 1993-04-06

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired