AU6138301A - Human monoclonal antibodies to dendritic cells - Google Patents
Human monoclonal antibodies to dendritic cellsInfo
- Publication number
- AU6138301A AU6138301A AU6138301A AU6138301A AU6138301A AU 6138301 A AU6138301 A AU 6138301A AU 6138301 A AU6138301 A AU 6138301A AU 6138301 A AU6138301 A AU 6138301A AU 6138301 A AU6138301 A AU 6138301A
- Authority
- AU
- Australia
- Prior art keywords
- human
- antibodies
- monoclonal antibodies
- dendritic cells
- human monoclonal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004443 dendritic cell Anatomy 0.000 title abstract 2
- 241001465754 Metazoa Species 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 230000009261 transgenic effect Effects 0.000 abstract 2
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 210000004408 hybridoma Anatomy 0.000 abstract 1
- 229940051026 immunotoxin Drugs 0.000 abstract 1
- 239000002596 immunotoxin Substances 0.000 abstract 1
- 231100000608 immunotoxin Toxicity 0.000 abstract 1
- 230000002637 immunotoxin Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000005215 recombination Methods 0.000 abstract 1
- 230000006798 recombination Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 238000011830 transgenic mouse model Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6056—Antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/54—F(ab')2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Food Science & Technology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Rheumatology (AREA)
- Biotechnology (AREA)
- Communicable Diseases (AREA)
- Pathology (AREA)
- Rehabilitation Therapy (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20312600P | 2000-05-08 | 2000-05-08 | |
| US23073900P | 2000-09-07 | 2000-09-07 | |
| PCT/US2001/015114 WO2001085798A2 (en) | 2000-05-08 | 2001-05-08 | Human monoclonal antibodies to dendritic cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU6138301A true AU6138301A (en) | 2001-11-20 |
Family
ID=26898333
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001261383A Ceased AU2001261383B2 (en) | 2000-05-08 | 2001-05-08 | Human monoclonal antibodies to dendritic cells |
| AU6138301A Pending AU6138301A (en) | 2000-05-08 | 2001-05-08 | Human monoclonal antibodies to dendritic cells |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001261383A Ceased AU2001261383B2 (en) | 2000-05-08 | 2001-05-08 | Human monoclonal antibodies to dendritic cells |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7563876B2 (enExample) |
| EP (1) | EP1282646B1 (enExample) |
| JP (1) | JP5007409B2 (enExample) |
| KR (2) | KR100643818B1 (enExample) |
| CN (1) | CN1452636B (enExample) |
| AT (1) | ATE553131T1 (enExample) |
| AU (2) | AU2001261383B2 (enExample) |
| CA (1) | CA2408594A1 (enExample) |
| DK (1) | DK1282646T3 (enExample) |
| IL (2) | IL152652A0 (enExample) |
| MX (1) | MXPA02010869A (enExample) |
| NZ (1) | NZ534864A (enExample) |
| WO (1) | WO2001085798A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004213749B2 (en) * | 2003-01-31 | 2010-02-25 | Celldex Therapeutics, Inc. | Antibody vaccine conjugates and uses therefor |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2408594A1 (en) | 2000-05-08 | 2001-11-15 | Medarex, Inc. | Human monoclonal antibodies to dendritic cells |
| US7560534B2 (en) * | 2000-05-08 | 2009-07-14 | Celldex Research Corporation | Molecular conjugates comprising human monoclonal antibodies to dendritic cells |
| US20060222633A1 (en) * | 2000-05-11 | 2006-10-05 | Yale University | Prevention, decrease, and/or treatment of immunoreactivity by depleting and/or inactivating antigen presenting cells in the host |
| US7754208B2 (en) | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
| AU2002240338C1 (en) | 2001-02-12 | 2007-05-17 | Medarex, Inc. | Human monoclonal antibodies to FC alpha receptor (CD89) |
| US20050215472A1 (en) | 2001-10-23 | 2005-09-29 | Psma Development Company, Llc | PSMA formulations and uses thereof |
| WO2003034903A2 (en) | 2001-10-23 | 2003-05-01 | Psma Development Company, L.L.C. | Psma antibodies and protein multimers |
| US9259459B2 (en) | 2003-01-31 | 2016-02-16 | Celldex Therapeutics Inc. | Antibody vaccine conjugates and uses therefor |
| US7901680B2 (en) * | 2005-10-19 | 2011-03-08 | Ibc Pharmaceuticals, Inc. | Dock-and-lock (DNL) vaccines for cancer therapy |
| CA2566473A1 (en) * | 2004-05-17 | 2005-12-08 | Board Of Trustees Of The University Of Illinois | Uses of bispecific antibody (biab) coated dendritic cells pulsed with antigens |
| WO2006073921A2 (en) * | 2004-12-30 | 2006-07-13 | The Rockefeller University | Compositions and methods for enhanced dendritic cell maturation and function |
| DK2298815T3 (en) | 2005-07-25 | 2015-06-15 | Emergent Product Dev Seattle | B-CELL REDUCTION USING CD37 SPECIFIC AND CD20 SPECIFIC BINDING MOLECULES |
| CN105837690A (zh) | 2006-06-12 | 2016-08-10 | 新兴产品开发西雅图有限公司 | 具有效应功能的单链多价结合蛋白 |
| JP2008029319A (ja) * | 2006-06-28 | 2008-02-14 | Yoichiro Iwakura | 樹状細胞免疫受容体遺伝子ノックアウト疾患モデル動物 |
| CA2704583A1 (en) | 2007-11-07 | 2009-05-14 | Celldex Therapeutics Inc. | Antibodies that bind human dendritic and epithelial cell 205 receptor(dec-205) |
| RS51975B (sr) | 2008-04-11 | 2012-02-29 | Emergent Product Development Seattle Llc. | Cd37 imunoterapeutski proizvod i njegova kombinacija sa bifunkcionalnim hemoterapeutskim sredstvom |
| WO2011091113A2 (en) | 2010-01-22 | 2011-07-28 | Immunomedics, Inc. | Detection of early-stage pancreatic adenocarcinoma |
| EP2727606A3 (en) | 2008-09-08 | 2015-09-23 | Psma Development Company, L.L.C. | Compounds for killing psma-expressing, taxane-resistant cancer cells |
| CN103415534A (zh) | 2009-03-10 | 2013-11-27 | 贝勒研究院 | 靶向抗原呈递细胞的癌症疫苗 |
| AU2010222942B2 (en) | 2009-03-10 | 2013-01-10 | Baylor Research Institute | Anti-CD40 antibodies and uses thereof |
| EP2477655A4 (en) * | 2009-09-14 | 2014-02-12 | Baylor Res Inst | VACCINES TREATED ON LANGERHANS CELLS |
| SG194701A1 (en) | 2011-04-29 | 2013-12-30 | Apexigen Inc | Anti-cd40 antibodies and methods of use |
| CN109608543A (zh) * | 2011-10-20 | 2019-04-12 | 艾斯巴技术-诺华有限责任公司 | 稳定的多抗原结合抗体 |
| WO2014066271A1 (en) * | 2012-10-22 | 2014-05-01 | Becton, Dickinson And Company | Non-b-lineage cells capable of producing antibody |
| KR102270618B1 (ko) | 2012-10-30 | 2021-06-30 | 아펙시젠, 인코포레이티드 | 항-cd40 항체 및 사용 방법 |
| CN120939216A (zh) | 2014-01-13 | 2025-11-14 | 贝勒研究院 | 抗hpv和hpv相关的疾病的新疫苗 |
| EP3352760A4 (en) | 2015-09-21 | 2019-03-06 | Aptevo Research and Development LLC | CD3-BINDING POLYPEPTIDES |
| US10610585B2 (en) | 2017-09-26 | 2020-04-07 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and compositions for treating and preventing HIV |
| KR20210089659A (ko) | 2018-10-05 | 2021-07-16 | 제노세라퓨틱스, 인코포레이티드 | 이종이식 생성물 및 방법 |
| US10883084B2 (en) | 2018-10-05 | 2021-01-05 | Xenotherapeutics, Inc. | Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non-human) donor and methods and products relating to same |
| CN113429481B (zh) * | 2021-07-07 | 2022-05-31 | 江苏农牧科技职业学院 | 一种靶向树突状细胞的纳米抗体分子及应用 |
| WO2023070317A1 (zh) * | 2021-10-26 | 2023-05-04 | 江苏省农业科学院 | 基于dc细胞的双功能纳米抗体及其构建方法和应用 |
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| WO2000000156A2 (en) | 1998-06-26 | 2000-01-06 | Trustees Of Dartmouth College | Methods for modulating immunological responses by targeting antigen to apcs in conjuction with anti-cd40 ligands |
| KR100295558B1 (ko) | 1998-06-27 | 2001-07-12 | 김기태 | 1차면역세포들중덴드리틱세포(dendriticcell)표면에특이하게작용하는단클론항체3-6-a |
| EP0997476A3 (en) | 1998-09-25 | 2000-07-19 | Schering-Plough | Antibodies to a mammalian Langerhans cell antigen and their uses |
| EP1046651A1 (en) * | 1999-04-19 | 2000-10-25 | Koninklijke Universiteit Nijmegen | Composition and method for modulating dendritic cell-T interaction |
| CA2408594A1 (en) | 2000-05-08 | 2001-11-15 | Medarex, Inc. | Human monoclonal antibodies to dendritic cells |
-
2001
- 2001-05-08 CA CA002408594A patent/CA2408594A1/en not_active Abandoned
- 2001-05-08 NZ NZ534864A patent/NZ534864A/en not_active IP Right Cessation
- 2001-05-08 WO PCT/US2001/015114 patent/WO2001085798A2/en not_active Ceased
- 2001-05-08 KR KR1020027014919A patent/KR100643818B1/ko not_active Expired - Fee Related
- 2001-05-08 AU AU2001261383A patent/AU2001261383B2/en not_active Ceased
- 2001-05-08 AT AT01935275T patent/ATE553131T1/de active
- 2001-05-08 KR KR1020067015862A patent/KR100881471B1/ko not_active Expired - Fee Related
- 2001-05-08 EP EP01935275A patent/EP1282646B1/en not_active Expired - Lifetime
- 2001-05-08 CN CN018124909A patent/CN1452636B/zh not_active Expired - Fee Related
- 2001-05-08 MX MXPA02010869A patent/MXPA02010869A/es active IP Right Grant
- 2001-05-08 AU AU6138301A patent/AU6138301A/xx active Pending
- 2001-05-08 JP JP2001582397A patent/JP5007409B2/ja not_active Expired - Fee Related
- 2001-05-08 IL IL15265201A patent/IL152652A0/xx unknown
- 2001-05-08 DK DK01935275.6T patent/DK1282646T3/da active
- 2001-05-08 US US09/851,614 patent/US7563876B2/en not_active Expired - Fee Related
-
2002
- 2002-11-05 IL IL152652A patent/IL152652A/en not_active IP Right Cessation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004213749B2 (en) * | 2003-01-31 | 2010-02-25 | Celldex Therapeutics, Inc. | Antibody vaccine conjugates and uses therefor |
Also Published As
| Publication number | Publication date |
|---|---|
| ATE553131T1 (de) | 2012-04-15 |
| CA2408594A1 (en) | 2001-11-15 |
| US7563876B2 (en) | 2009-07-21 |
| AU2001261383B2 (en) | 2004-10-21 |
| NZ534864A (en) | 2006-04-28 |
| CN1452636A (zh) | 2003-10-29 |
| WO2001085798A3 (en) | 2002-07-18 |
| IL152652A0 (en) | 2003-06-24 |
| IL152652A (en) | 2011-06-30 |
| KR20060094544A (ko) | 2006-08-29 |
| DK1282646T3 (da) | 2012-05-14 |
| JP5007409B2 (ja) | 2012-08-22 |
| CN1452636B (zh) | 2011-06-15 |
| HK1059442A1 (en) | 2004-07-02 |
| KR100643818B1 (ko) | 2006-11-10 |
| MXPA02010869A (es) | 2003-04-14 |
| KR20020092468A (ko) | 2002-12-11 |
| US20030167502A1 (en) | 2003-09-04 |
| KR100881471B1 (ko) | 2009-02-05 |
| WO2001085798A9 (en) | 2011-04-14 |
| WO2001085798A2 (en) | 2001-11-15 |
| JP2003532409A (ja) | 2003-11-05 |
| EP1282646B1 (en) | 2012-04-11 |
| EP1282646A2 (en) | 2003-02-12 |
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