AU6020898A - Substituted bis-acridines and related compounds as ccr5 receptor ligands, anti-inflammatory agents and anti-viral agents - Google Patents
Substituted bis-acridines and related compounds as ccr5 receptor ligands, anti-inflammatory agents and anti-viral agentsInfo
- Publication number
- AU6020898A AU6020898A AU60208/98A AU6020898A AU6020898A AU 6020898 A AU6020898 A AU 6020898A AU 60208/98 A AU60208/98 A AU 60208/98A AU 6020898 A AU6020898 A AU 6020898A AU 6020898 A AU6020898 A AU 6020898A
- Authority
- AU
- Australia
- Prior art keywords
- acridines
- agents
- related compounds
- receptor ligands
- substituted bis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/08—Nitrogen atoms
- C07D219/10—Nitrogen atoms attached in position 9
- C07D219/12—Amino-alkylamino radicals attached in position 9
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3514897P | 1997-01-08 | 1997-01-08 | |
| US60035148 | 1997-01-08 | ||
| PCT/US1998/000489 WO1998030218A1 (en) | 1997-01-08 | 1998-01-08 | Substituted bis-acridines and related compounds as ccr5 receptor ligands, anti-inflammatory agents and anti-viral agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU6020898A true AU6020898A (en) | 1998-08-03 |
Family
ID=21880954
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU60208/98A Abandoned AU6020898A (en) | 1997-01-08 | 1998-01-08 | Substituted bis-acridines and related compounds as ccr5 receptor ligands, anti-inflammatory agents and anti-viral agents |
Country Status (9)
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6025154A (en) | 1995-06-06 | 2000-02-15 | Human Genome Sciences, Inc. | Polynucleotides encoding human G-protein chemokine receptor HDGNR10 |
| US6743594B1 (en) | 1995-06-06 | 2004-06-01 | Human Genome Sciences, Inc. | Methods of screening using human G-protein chemokine receptor HDGNR10 (CCR5) |
| US6514987B1 (en) * | 1997-01-06 | 2003-02-04 | Cerus Corporation | Frangible compounds for pathogen inactivation |
| ZA985542B (en) | 1997-07-03 | 1999-04-07 | Smithkline Beecham Corp | Substituted benzanilides as CCR5 receptor ligands antiinflammatory agents and antiviral agents |
| EP1535909A3 (en) | 1997-11-18 | 2005-07-13 | Teijin Limited | Cyclic amine derivatives and their use as drugs |
| DE60023878T2 (de) | 1999-05-18 | 2006-07-20 | Teijin Ltd. | Heilmittel und vorbeugung für mit chemokinen verbundenen erkrankungen |
| CA2412345A1 (en) * | 1999-06-16 | 2000-12-21 | University Of Iowa Research Foundation | Antagonism of immunostimulatory cpg-oligonucleotides by 4-aminoquinolines and other weak bases |
| AU779610B2 (en) | 1999-08-04 | 2005-02-03 | Teijin Limited | Cyclic amine CCR3 antagonists |
| WO2001042208A1 (fr) * | 1999-12-08 | 2001-06-14 | Teijin Limited | Antagonistes du recepteur ccr5 de la cycloamine |
| US6410566B1 (en) | 2000-05-16 | 2002-06-25 | Teijin Limited | Cyclic amine derivatives and their use as drugs |
| US7160896B2 (en) | 2000-07-07 | 2007-01-09 | Cancer Research Technology Limited | Therapeutic acridone and acridine compounds |
| US7175988B2 (en) | 2001-02-09 | 2007-02-13 | Human Genome Sciences, Inc. | Human G-protein Chemokine Receptor (CCR5) HDGNR10 |
| US7393934B2 (en) | 2001-12-21 | 2008-07-01 | Human Genome Sciences, Inc. | Human G-protein chemokine receptor (CCR5) HDGNR10 |
| AU2003207646C1 (en) * | 2002-01-22 | 2008-09-18 | Vanderbilt University | Treating stress response with chemokine receptor CCR5 modulators |
| AU2003261103A1 (en) * | 2002-07-02 | 2004-01-23 | Uab Research Foundation | Compounds promoting delivery of genes |
| WO2005105841A2 (en) | 2004-03-12 | 2005-11-10 | Human Genome Sciences, Inc. | Human g-protein chemokine receptor (ccr5) hdgnr10 |
| WO2008030853A2 (en) * | 2006-09-06 | 2008-03-13 | Incyte Corporation | Combination therapy for human immunodeficiency virus infection |
| US20140271680A1 (en) | 2011-08-12 | 2014-09-18 | Universite Paris-Est Creteil Val De Marne | Methods and pharmaceutical compositions for treatment of pulmonary hypertension |
| US10149830B2 (en) | 2016-06-03 | 2018-12-11 | Cushing Academy | Pharmaceutical agents and methods relating thereto |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2503899A (en) * | 1945-08-29 | 1950-04-11 | Dow Chemical Co | Diacridyl diamine derivatives |
| FR2314165A1 (fr) * | 1975-06-13 | 1977-01-07 | Anvar | Nouveaux bis (anthryl-9) alcanes et leur preparation |
| FR2588259B1 (fr) * | 1985-10-04 | 1988-01-22 | Aix Marseille Universite | Bis-acridiniques monopontes et bis-acridiniques bipontes |
| JPH0688924B2 (ja) * | 1986-05-28 | 1994-11-09 | ダイセル化学工業株式会社 | 光記憶材料 |
| DE4014421A1 (de) * | 1990-05-05 | 1991-11-07 | Merck Patent Gmbh | Aminosaeurederivate |
| JPH04226467A (ja) * | 1990-09-13 | 1992-08-17 | Ricoh Co Ltd | 電子写真感光体の疲労回復方法 |
| EP0570594B1 (en) * | 1991-12-10 | 1997-07-30 | Shionogi & Co., Ltd. | Hydroxamic acid derivative based on aromatic sulfonamide |
| DE4405378A1 (de) * | 1994-02-19 | 1995-08-24 | Merck Patent Gmbh | Adhäsionsrezeptor-Antagonisten |
-
1998
- 1998-01-05 AR ARP980100032A patent/AR011057A1/es unknown
- 1998-01-07 ZA ZA9895A patent/ZA9895B/xx unknown
- 1998-01-07 CO CO98000422A patent/CO4920243A1/es unknown
- 1998-01-08 EP EP98903437A patent/EP0979078A4/en not_active Withdrawn
- 1998-01-08 CA CA002276525A patent/CA2276525A1/en not_active Abandoned
- 1998-01-08 JP JP53117498A patent/JP2001509152A/ja active Pending
- 1998-01-08 WO PCT/US1998/000489 patent/WO1998030218A1/en not_active Application Discontinuation
- 1998-01-08 AU AU60208/98A patent/AU6020898A/en not_active Abandoned
- 1998-01-08 US US09/341,171 patent/US6242459B1/en not_active Expired - Fee Related
-
2001
- 2001-04-11 US US09/833,044 patent/US20010031763A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20010031763A1 (en) | 2001-10-18 |
| JP2001509152A (ja) | 2001-07-10 |
| US6242459B1 (en) | 2001-06-05 |
| CO4920243A1 (es) | 2000-05-29 |
| EP0979078A4 (en) | 2000-06-21 |
| ZA9895B (en) | 1998-07-08 |
| WO1998030218A1 (en) | 1998-07-16 |
| CA2276525A1 (en) | 1998-07-16 |
| EP0979078A1 (en) | 2000-02-16 |
| AR011057A1 (es) | 2000-08-02 |
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