AU599367B2 - Novel amino acid derivatives - Google Patents

Novel amino acid derivatives Download PDF

Info

Publication number
AU599367B2
AU599367B2 AU70944/87A AU7094487A AU599367B2 AU 599367 B2 AU599367 B2 AU 599367B2 AU 70944/87 A AU70944/87 A AU 70944/87A AU 7094487 A AU7094487 A AU 7094487A AU 599367 B2 AU599367 B2 AU 599367B2
Authority
AU
Australia
Prior art keywords
amino acid
group
formula
mixture
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU70944/87A
Other languages
English (en)
Other versions
AU7094487A (en
Inventor
Kenji Akahane
Kinji Iizuka
Tetsuhide Kamijo
Yoshiaki Kiso
Tetsuhiro Kubota
Hideaki Umeyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kissei Pharmaceutical Co Ltd
Original Assignee
Kissei Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP61074511A external-priority patent/JPS62234071A/ja
Priority claimed from JP61162563A external-priority patent/JPS6317867A/ja
Application filed by Kissei Pharmaceutical Co Ltd filed Critical Kissei Pharmaceutical Co Ltd
Publication of AU7094487A publication Critical patent/AU7094487A/en
Application granted granted Critical
Publication of AU599367B2 publication Critical patent/AU599367B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/86—Renin inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU70944/87A 1986-04-01 1987-04-01 Novel amino acid derivatives Ceased AU599367B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP61074511A JPS62234071A (ja) 1986-04-01 1986-04-01 新規なアミノ酸誘導体
JP61-74511 1986-04-01
JP61-162563 1986-07-10
JP61162563A JPS6317867A (ja) 1986-07-10 1986-07-10 新規なアミノ酸誘導体

Publications (2)

Publication Number Publication Date
AU7094487A AU7094487A (en) 1987-10-08
AU599367B2 true AU599367B2 (en) 1990-07-19

Family

ID=26415660

Family Applications (1)

Application Number Title Priority Date Filing Date
AU70944/87A Ceased AU599367B2 (en) 1986-04-01 1987-04-01 Novel amino acid derivatives

Country Status (7)

Country Link
US (1) US4711958A (enExample)
EP (1) EP0244083A3 (enExample)
KR (1) KR870010078A (enExample)
AU (1) AU599367B2 (enExample)
FI (1) FI871406A7 (enExample)
HU (1) HU200191B (enExample)
NO (1) NO871295L (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0181110A3 (en) * 1984-10-22 1988-05-11 Kissei Pharmaceutical Co. Ltd. Histidine derivatives as renin inhibitors
EP0190891A3 (en) * 1985-01-31 1988-04-20 Kissei Pharmaceutical Co. Ltd. Novel amino acid derivatives
EP0206807A3 (en) * 1985-06-28 1988-01-20 Kissei Pharmaceutical Co. Ltd. Novel amino acid derivatives
US4853463A (en) * 1985-09-04 1989-08-01 Kissei Pharmaceutical Co., Ltd. Amino acid derivatives
JPS6322081A (ja) * 1986-07-11 1988-01-29 Kissei Pharmaceut Co Ltd 新規なアミノ酸誘導体
US4814342A (en) * 1986-10-31 1989-03-21 Pfizer Inc. Nor-statine and nor-cyclostatine polypeptides
FI89058C (fi) * 1987-02-27 1993-08-10 Yamanouchi Pharma Co Ltd Foerfarande foer framstaellning av som remin-inhibitorer anvaenda 2-(l-alanyl-l-histidylamino)-butanol-derivat
GB8707412D0 (en) * 1987-03-27 1987-04-29 Fujisawa Pharmaceutical Co Peptide compounds
US4921855A (en) * 1987-06-22 1990-05-01 Fujisawa Pharmaceutical Co., Ltd. New Histidyl amino acid derivatives, and pharmaceutical composition comprising the same
US5151513A (en) * 1988-04-29 1992-09-29 E. R. Squibb & Sons, Inc. N-heterocyclic alcohol derivatives
IL91780A (en) * 1988-10-04 1995-08-31 Abbott Lab History of the amine of the xenon-preventing xanine acid, the process for their preparation and the pharmaceutical preparations containing them
US5268374A (en) * 1988-10-04 1993-12-07 Abbott Laboratories Non-peptide renin inhibitors
US4965372A (en) * 1989-01-19 1990-10-23 Pfizer Inc. Process and intermediates for isopropyl 3S-amino-2R-hydroxy-alkanoates
US5166400A (en) * 1989-01-19 1992-11-24 Pfizer Inc. Intermediates for isopropyl 3S-amino-2R-hydroxy-alkanoates
US5036155A (en) * 1989-06-29 1991-07-30 Pfizer Inc. Process for isopropyl 3S-amino-2R-hydroxy-alkanoates
US5104869A (en) * 1989-10-11 1992-04-14 American Cyanamid Company Renin inhibitors
US6313094B1 (en) * 1990-12-11 2001-11-06 Japan Energy Corporation β-amino-α-hydroxycarboxylic acid derivatives and HIV protease inhibitors
US5114925A (en) * 1991-01-22 1992-05-19 Merck & Co., Inc. Renin inhibitors containing the 2-[[(2R,3S)-3-amino-4-cyclohexyl-2-hydroxy-1-butyl]thio)alkanoyl moiety and the corresponding sulfoxide and sulfone derivatives
US5442105A (en) * 1991-06-21 1995-08-15 Takasago International Corporation Process for producing cyclohexylbutyric acid derivative
JP2847584B2 (ja) * 1991-06-21 1999-01-20 高砂香料工業株式会社 シクロヘキシル酪酸誘導体及びその製造法
US5399763A (en) * 1993-02-01 1995-03-21 Nippon Kayaku Kabushiki Kaisha Process for preparing optically active 2-aminopropanal
AU2959397A (en) * 1996-05-31 1998-01-05 Novartis Ag Process for the preparation of hydrazine derivatives useful as intermediates for the preparation of peptide analogues

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4656269A (en) * 1986-04-15 1987-04-07 Kissei Pharmaceutical Co., Ltd. Histidine derivatives
AU1250288A (en) * 1987-02-27 1988-09-01 Yamanouchi Pharmaceutical Co., Ltd. Improvements in or relating to histidine derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1245217A (en) * 1981-12-10 1988-11-22 Joshua S. Boger Renin inhibitory peptides having phe su13 xx deletion
JPS61236770A (ja) * 1985-04-15 1986-10-22 Kissei Pharmaceut Co Ltd 新規なアミノ酸誘導体

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4656269A (en) * 1986-04-15 1987-04-07 Kissei Pharmaceutical Co., Ltd. Histidine derivatives
US4656269B1 (enExample) * 1986-04-15 1989-08-29
AU1250288A (en) * 1987-02-27 1988-09-01 Yamanouchi Pharmaceutical Co., Ltd. Improvements in or relating to histidine derivatives

Also Published As

Publication number Publication date
FI871406A7 (fi) 1987-10-02
FI871406A0 (fi) 1987-03-31
HUT44043A (en) 1988-01-28
KR870010078A (ko) 1987-11-30
US4711958B1 (enExample) 1989-08-29
US4711958A (en) 1987-12-08
EP0244083A3 (en) 1989-11-15
NO871295D0 (no) 1987-03-27
HU200191B (en) 1990-04-28
AU7094487A (en) 1987-10-08
NO871295L (no) 1987-10-02
EP0244083A2 (en) 1987-11-04

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