AU590870B2 - 1,6-naphthyridin-2(1H)- ones having cardiotonic activity and preparation - Google Patents

1,6-naphthyridin-2(1H)- ones having cardiotonic activity and preparation

Info

Publication number
AU590870B2
AU590870B2 AU52447/86A AU5244786A AU590870B2 AU 590870 B2 AU590870 B2 AU 590870B2 AU 52447/86 A AU52447/86 A AU 52447/86A AU 5244786 A AU5244786 A AU 5244786A AU 590870 B2 AU590870 B2 AU 590870B2
Authority
AU
Australia
Prior art keywords
naphthyridin
ones
preparation
cardiotonic activity
cardiotonic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
AU52447/86A
Other languages
English (en)
Other versions
AU5244786A (en
Inventor
George Yohe Lesher
Baldev Singh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STWB Inc
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of AU5244786A publication Critical patent/AU5244786A/en
Application granted granted Critical
Publication of AU590870B2 publication Critical patent/AU590870B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
AU52447/86A 1985-01-28 1986-01-17 1,6-naphthyridin-2(1H)- ones having cardiotonic activity and preparation Expired - Fee Related AU590870B2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US69560385A 1985-01-28 1985-01-28
US695603 1985-01-28
US76590085A 1985-08-14 1985-08-14
US765900 1985-08-14
US81104085A 1985-12-19 1985-12-19
US811040 1985-12-19

Publications (2)

Publication Number Publication Date
AU5244786A AU5244786A (en) 1986-07-31
AU590870B2 true AU590870B2 (en) 1989-11-23

Family

ID=27418622

Family Applications (1)

Application Number Title Priority Date Filing Date
AU52447/86A Expired - Fee Related AU590870B2 (en) 1985-01-28 1986-01-17 1,6-naphthyridin-2(1H)- ones having cardiotonic activity and preparation

Country Status (12)

Country Link
EP (1) EP0189853A3 (pt)
KR (1) KR870006046A (pt)
AU (1) AU590870B2 (pt)
DK (1) DK32086A (pt)
ES (1) ES8800221A1 (pt)
FI (1) FI860305A (pt)
GR (1) GR860180B (pt)
IL (1) IL77670A (pt)
NO (1) NO860230L (pt)
NZ (1) NZ214837A (pt)
PH (1) PH22347A (pt)
PT (1) PT81894B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4567186A (en) * 1985-01-14 1986-01-28 Sterling Drug Inc. 5-Heteryl-1,6-naphthyridin-2(1H)-ones, cardiotonic use thereof and intermediates therefor
MXPA05008612A (es) * 2003-02-14 2005-12-05 Smithkline Beecham Corp Compuestos novedosos.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415580A (en) * 1982-08-02 1983-11-15 Sterling Drug Inc. Certain 2-(1H)-pyridinones cardiotonic compositions containing same and method of using same
PT79699B (en) * 1983-12-22 1986-12-10 Pfizer Process for preparing quinolone inotropic agents
US4560691A (en) * 1984-07-13 1985-12-24 Sterling Drug Inc. 5-(Phenyl)-1,6-naphthyridin-2(1H)-ones, their cardiotonic use and preparation

Also Published As

Publication number Publication date
AU5244786A (en) 1986-07-31
GR860180B (en) 1986-05-29
FI860305A0 (fi) 1986-01-22
EP0189853A3 (en) 1987-12-16
PT81894B (en) 1987-05-05
EP0189853A2 (en) 1986-08-06
PH22347A (en) 1988-08-12
KR870006046A (ko) 1987-07-08
ES8800221A1 (es) 1987-11-01
FI860305A (fi) 1986-07-29
IL77670A (en) 1989-05-15
NO860230L (no) 1986-07-29
NZ214837A (en) 1988-10-28
DK32086A (da) 1986-07-29
ES551258A0 (es) 1987-11-01
DK32086D0 (da) 1986-01-22
PT81894A (en) 1986-02-01

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