AU5823600A - Cyclic peptide derivatives as inhibitors of integrin alphavbeta6 - Google Patents
Cyclic peptide derivatives as inhibitors of integrin alphavbeta6Info
- Publication number
- AU5823600A AU5823600A AU58236/00A AU5823600A AU5823600A AU 5823600 A AU5823600 A AU 5823600A AU 58236/00 A AU58236/00 A AU 58236/00A AU 5823600 A AU5823600 A AU 5823600A AU 5823600 A AU5823600 A AU 5823600A
- Authority
- AU
- Australia
- Prior art keywords
- integrin
- inhibitors
- cyclic peptide
- peptide derivatives
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biochemistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Communicable Diseases (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19933173 | 1999-07-15 | ||
DE19933173A DE19933173A1 (en) | 1999-07-15 | 1999-07-15 | Cyclic peptide derivatives as inhibitors of the integrin alpha¶v¶beta¶6¶ |
PCT/EP2000/006188 WO2001005810A2 (en) | 1999-07-15 | 2000-07-03 | CYCLIC PEPTIDE DERIVATIVES AS INHIBITORS OF INTEGRIN αVβ¿6? |
Publications (3)
Publication Number | Publication Date |
---|---|
AU5823600A true AU5823600A (en) | 2001-02-05 |
AU772782B2 AU772782B2 (en) | 2004-05-06 |
AU772782C AU772782C (en) | 2005-01-27 |
Family
ID=7914891
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU58236/00A Ceased AU772782C (en) | 1999-07-15 | 2000-07-03 | Cyclic peptide derivatives as inhibitors of integrin alphavbeta6 |
Country Status (23)
Country | Link |
---|---|
EP (2) | EP1754714A1 (en) |
JP (1) | JP2003505395A (en) |
KR (1) | KR20020010928A (en) |
CN (1) | CN1361792A (en) |
AR (1) | AR024742A1 (en) |
AT (1) | ATE340803T1 (en) |
AU (1) | AU772782C (en) |
BR (1) | BR0012418A (en) |
CA (1) | CA2379022A1 (en) |
CZ (1) | CZ200226A3 (en) |
DE (2) | DE19933173A1 (en) |
DK (1) | DK1196433T3 (en) |
ES (1) | ES2273703T3 (en) |
HK (1) | HK1048641A1 (en) |
HU (1) | HUP0201925A3 (en) |
MX (1) | MXPA02000465A (en) |
NO (1) | NO20020176D0 (en) |
PL (1) | PL354363A1 (en) |
PT (1) | PT1196433E (en) |
SK (1) | SK262002A3 (en) |
TW (1) | TWI226890B (en) |
WO (1) | WO2001005810A2 (en) |
ZA (1) | ZA200201275B (en) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002232176B2 (en) * | 2001-02-19 | 2006-06-15 | Takara Bio Inc. | Cyclic peptide |
DE10118550A1 (en) * | 2001-04-14 | 2002-10-17 | Merck Patent Gmbh | New 3-ethanoylamino-3-phenyl-propionic acid derivatives, are integrin agonists or antagonists useful e.g. for treating angiogenic, cardiovascular, inflammatory, osteolytic or tumor diseases or infections |
DK1667668T3 (en) * | 2003-10-01 | 2008-09-15 | Merck Patent Gmbh | Alphabeta3 and altabeta6 integrin antagonists as antifibrotic agents |
BRPI0417250A (en) * | 2003-12-03 | 2007-03-06 | Scripps Research Inst | isolated and purified peptides and polynucleotide, antibodies, vector, host cell, methods of inhibiting platelet aggregation, binding of fibrinogen to platelets, use of polynucleotide for protein production and treatment of person and pharmaceutical compositions |
US7361636B2 (en) | 2004-10-06 | 2008-04-22 | Amr Technology, Inc. | Cyclosporin alkynes and their utility as pharmaceutical agents |
GB0520068D0 (en) * | 2005-10-03 | 2005-11-09 | Cancer Res Technology | av peptide ligand |
US7696166B2 (en) | 2006-03-28 | 2010-04-13 | Albany Molecular Research, Inc. | Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders |
US7696165B2 (en) | 2006-03-28 | 2010-04-13 | Albany Molecular Research, Inc. | Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders |
MX2009001293A (en) | 2006-08-03 | 2009-02-11 | Astrazeneca Ab | Antibodies directed to â¿vãy6 and uses thereof. |
EP2784511A1 (en) | 2013-03-27 | 2014-10-01 | Universität Zürich | Integrin alpha-v-beta6 for diagnosis/prognosis of colorectal carcinoma |
SI3350222T1 (en) * | 2015-09-18 | 2022-01-31 | Technische Universitaet Muenchen | Ligands for integrin avbeta6, synthesis and uses thereof |
MA52117A (en) | 2017-02-28 | 2022-04-06 | Morphic Therapeutic Inc | INHIBITORS OF INTEGRIN (ALPHA-V) (BETA-6) |
EP4159727A1 (en) | 2017-02-28 | 2023-04-05 | Morphic Therapeutic, Inc. | Inhibitors of (alpha-v)(beta-6) integrin |
WO2018167295A1 (en) | 2017-03-17 | 2018-09-20 | Technische Universität München | LIGANDS FOR INTEGRIN αvβ8, SYNTHESIS AND USES THEREOF |
GB201706472D0 (en) * | 2017-04-24 | 2017-06-07 | Cancer Res Tech Ltd | Tumour-targeting peptide variants |
PE20211640A1 (en) | 2018-08-29 | 2021-08-24 | Morphic Therapeutic Inc | INHIBITION OF INTEGRIN xvß6 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4472305A (en) | 1983-05-17 | 1984-09-18 | Sterling Drug Inc. | Hexapeptide amides |
DE4310643A1 (en) | 1993-04-01 | 1994-10-06 | Merck Patent Gmbh | Cyclic adhesion inhibitors |
DE19538741A1 (en) | 1995-10-18 | 1997-04-24 | Merck Patent Gmbh | Cyclopeptide derivatives |
CA2355874A1 (en) * | 1998-12-19 | 2000-06-29 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | .alpha.v.beta.6 integrin inhibitors |
-
1999
- 1999-07-15 DE DE19933173A patent/DE19933173A1/en not_active Withdrawn
-
2000
- 2000-07-03 CN CN00810415A patent/CN1361792A/en active Pending
- 2000-07-03 PT PT00943971T patent/PT1196433E/en unknown
- 2000-07-03 AT AT00943971T patent/ATE340803T1/en not_active IP Right Cessation
- 2000-07-03 DK DK00943971T patent/DK1196433T3/en active
- 2000-07-03 CZ CZ200226A patent/CZ200226A3/en unknown
- 2000-07-03 JP JP2001511467A patent/JP2003505395A/en active Pending
- 2000-07-03 CA CA002379022A patent/CA2379022A1/en not_active Abandoned
- 2000-07-03 SK SK26-2002A patent/SK262002A3/en unknown
- 2000-07-03 KR KR1020017015995A patent/KR20020010928A/en not_active Application Discontinuation
- 2000-07-03 ES ES00943971T patent/ES2273703T3/en not_active Expired - Lifetime
- 2000-07-03 WO PCT/EP2000/006188 patent/WO2001005810A2/en active IP Right Grant
- 2000-07-03 BR BR0012418-4A patent/BR0012418A/en not_active Application Discontinuation
- 2000-07-03 EP EP06019918A patent/EP1754714A1/en not_active Withdrawn
- 2000-07-03 HU HU0201925A patent/HUP0201925A3/en unknown
- 2000-07-03 EP EP00943971A patent/EP1196433B1/en not_active Expired - Lifetime
- 2000-07-03 DE DE50013525T patent/DE50013525D1/en not_active Expired - Fee Related
- 2000-07-03 MX MXPA02000465A patent/MXPA02000465A/en unknown
- 2000-07-03 PL PL00354363A patent/PL354363A1/en unknown
- 2000-07-03 AU AU58236/00A patent/AU772782C/en not_active Ceased
- 2000-07-13 TW TW089113997A patent/TWI226890B/en not_active IP Right Cessation
- 2000-07-14 AR ARP000103621A patent/AR024742A1/en unknown
-
2002
- 2002-01-14 NO NO20020176A patent/NO20020176D0/en unknown
- 2002-02-14 ZA ZA200201275A patent/ZA200201275B/en unknown
-
2003
- 2003-01-15 HK HK03100378.9A patent/HK1048641A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
HK1048641A1 (en) | 2003-04-11 |
ES2273703T3 (en) | 2007-05-16 |
SK262002A3 (en) | 2002-07-02 |
TWI226890B (en) | 2005-01-21 |
BR0012418A (en) | 2002-03-26 |
PL354363A1 (en) | 2004-01-12 |
ZA200201275B (en) | 2003-08-22 |
HUP0201925A2 (en) | 2002-10-28 |
DE19933173A1 (en) | 2001-01-18 |
CN1361792A (en) | 2002-07-31 |
JP2003505395A (en) | 2003-02-12 |
KR20020010928A (en) | 2002-02-06 |
MXPA02000465A (en) | 2002-07-30 |
PT1196433E (en) | 2007-01-31 |
WO2001005810A3 (en) | 2001-05-17 |
EP1754714A1 (en) | 2007-02-21 |
NO20020176L (en) | 2002-01-14 |
NO20020176D0 (en) | 2002-01-14 |
AU772782C (en) | 2005-01-27 |
DE50013525D1 (en) | 2006-11-09 |
EP1196433A2 (en) | 2002-04-17 |
CA2379022A1 (en) | 2001-01-25 |
ATE340803T1 (en) | 2006-10-15 |
CZ200226A3 (en) | 2002-04-17 |
DK1196433T3 (en) | 2007-02-12 |
EP1196433B1 (en) | 2006-09-27 |
AR024742A1 (en) | 2002-10-23 |
WO2001005810A2 (en) | 2001-01-25 |
AU772782B2 (en) | 2004-05-06 |
HUP0201925A3 (en) | 2002-11-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
DA2 | Applications for amendment section 104 |
Free format text: THE NATURE OF THE PROPOSED AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 20040615 |
|
FGA | Letters patent sealed or granted (standard patent) |