AU5811994A - Tryptamine analogues as 5-ht1-like agonists - Google Patents

Tryptamine analogues as 5-ht1-like agonists

Info

Publication number
AU5811994A
AU5811994A AU58119/94A AU5811994A AU5811994A AU 5811994 A AU5811994 A AU 5811994A AU 58119/94 A AU58119/94 A AU 58119/94A AU 5811994 A AU5811994 A AU 5811994A AU 5811994 A AU5811994 A AU 5811994A
Authority
AU
Australia
Prior art keywords
agonists
tryptamine
analogues
tryptamine analogues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU58119/94A
Inventor
William John Coates
Roderick Alan Porter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Publication of AU5811994A publication Critical patent/AU5811994A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU58119/94A 1992-12-21 1993-12-14 Tryptamine analogues as 5-ht1-like agonists Abandoned AU5811994A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB929226537A GB9226537D0 (en) 1992-12-21 1992-12-21 Compounds
GB9226537 1992-12-21
PCT/EP1993/003564 WO1994014771A1 (en) 1992-12-21 1993-12-14 Tryptamine analogues as 5-ht1-like agonists

Publications (1)

Publication Number Publication Date
AU5811994A true AU5811994A (en) 1994-07-19

Family

ID=10726916

Family Applications (1)

Application Number Title Priority Date Filing Date
AU58119/94A Abandoned AU5811994A (en) 1992-12-21 1993-12-14 Tryptamine analogues as 5-ht1-like agonists

Country Status (7)

Country Link
EP (1) EP0674620A1 (en)
JP (1) JPH08504786A (en)
CN (1) CN1092765A (en)
AU (1) AU5811994A (en)
GB (1) GB9226537D0 (en)
WO (1) WO1994014771A1 (en)
ZA (1) ZA939456B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2273328C (en) * 1996-11-26 2009-04-28 Abdelmalik Slassi 5-cyclo indole compounds as 5-ht1d receptor ligands
ATE252572T1 (en) * 1998-06-30 2003-11-15 Lilly Co Eli 5-HT1F AGONISTS
CA2375909A1 (en) 1999-07-19 2001-01-25 Shionogi & Co., Ltd. Tricyclic compounds bearing acyloxymethoxycarbonyl pendants
AU7962200A (en) * 1999-10-29 2001-05-14 Wakunaga Pharmaceutical Co., Ltd Novel indole derivatives and drugs containing the same as the active ingredient
WO2001034146A1 (en) * 1999-11-08 2001-05-17 Smithkline Beecham Corporation Novel anti-infectives
DE19963178A1 (en) 1999-12-27 2001-07-05 Gruenenthal Gmbh Substituted indole Mannich bases
WO2001055361A2 (en) 2000-01-26 2001-08-02 Chiron Corporation Recombinant aav packaging systems
JP2005526691A (en) * 2001-08-08 2005-09-08 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー Therapeutic agent 1H-pyrido [4,3-b] indole
DE10209520A1 (en) * 2002-03-04 2003-09-25 4Sc Ag New modulators of potassium channels
US6906095B2 (en) 2002-05-10 2005-06-14 Wyeth Indolylalkylidenehydrazine-carboximidamide derivatives as 5-hydroxytryptamine-6 ligands
US6951881B2 (en) 2002-05-10 2005-10-04 Wyeth (1-substituted-indol-3-yl) alkylidenehydrazinecarboximidamide derivatives as 5-hydroxytryptamine-6 ligands
US7423044B2 (en) * 2002-09-05 2008-09-09 Wyeth Pyrimidine derivatives useful in the treatment of insulin resistance and hyperglycemia
CA2508290C (en) 2002-12-20 2017-02-28 Ciba Specialty Chemicals Holding Inc. Synthesis of amines and intermediates for the synthesis thereof
KR20070083484A (en) * 2004-07-14 2007-08-24 피티씨 테라퓨틱스, 인크. Methods for treating hepatitis c
US7781478B2 (en) 2004-07-14 2010-08-24 Ptc Therapeutics, Inc. Methods for treating hepatitis C
WO2010034671A1 (en) * 2008-09-26 2010-04-01 F. Hoffmann-La Roche Ag Pyrine or pyrazine derivatives for treating hcv
SG177628A1 (en) 2009-07-30 2012-03-29 Univ Singapore Small molecule inhibitors of isoprenylcysteine carboxyl methyltransferase with potential anticancer activity
CN114249681A (en) * 2021-11-22 2022-03-29 宁波大学 7-fluoro-5-substituted tryptamine compound and preparation method and application thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4833153A (en) * 1985-11-08 1989-05-23 Glaxo Group Limited Indole derivatives
GB8724912D0 (en) * 1987-10-23 1987-11-25 Wellcome Found Indole derivatives
IL96891A0 (en) * 1990-01-17 1992-03-29 Merck Sharp & Dohme Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them
SK278998B6 (en) * 1991-02-01 1998-05-06 Merck Sharp & Dohme Limited Imidazole, triazole and tetrazole derivatives, method of producing same, their use and pharmaceutical compositons on their base
TW263508B (en) * 1991-02-12 1995-11-21 Pfizer
HUT64023A (en) * 1991-03-22 1993-11-29 Sandoz Ag Process for producing aminoguanidine derivatives and pharmaceutical compositions comprising such compounds

Also Published As

Publication number Publication date
CN1092765A (en) 1994-09-28
ZA939456B (en) 1995-06-19
WO1994014771A1 (en) 1994-07-07
GB9226537D0 (en) 1993-02-17
JPH08504786A (en) 1996-05-21
EP0674620A1 (en) 1995-10-04

Similar Documents

Publication Publication Date Title
AU3952693A (en) Indole derivatives as 5-HT1-like agonists
AU6666990A (en) Indole derivatives
EP0516349A3 (en) 2-hydroxy-2-phenylethylamine derivatives as beta-3-adrenoceptor agonists
AU4156293A (en) Thiazolylvinylphenyl derivatives
AU3337193A (en) Telescopic-sight mount
AU6101190A (en) Soilresisting agent
AU5811994A (en) Tryptamine analogues as 5-ht1-like agonists
AU8137391A (en) Spray system
AU2309788A (en) Melatonin analogues
AU639600B2 (en) Waterproofing agent for cable
AU685767B2 (en) Substituted benzazepinones
AU2327192A (en) Indoles
AU3679693A (en) Benzimidazoles
AU3406793A (en) 2-oxoquinoline derivatives
AU5447094A (en) Polysubstituted benzimidazoles as antiviral agents
AU6571594A (en) Thioindole pyperidinyl derivatives used as antalgics
AU632380B2 (en) 13-epi-avermectin derivatives useful as antiparasitic agents
AU6994396A (en) Substituted indolylpropyl-piperazine derivatives as 5-ht1dalpha agonists
AU3697893A (en) Propenoyl-imidazole derivatives
AU4299989A (en) Coating compositions
AU5593794A (en) Pyridazinoquinazolone derivatives as neurotrophic agents
AU4316189A (en) Substituted indazole arthropodicides
AU3132089A (en) Imidazole derivatives
AU4167293A (en) Heterocyclyl-phenoxyalkyl-piperidinylpyridazines as antiviral agents
AU3682789A (en) Spraying apparatus