AU5799098A - Preparation of gabapentin - Google Patents

Preparation of gabapentin

Info

Publication number
AU5799098A
AU5799098A AU57990/98A AU5799098A AU5799098A AU 5799098 A AU5799098 A AU 5799098A AU 57990/98 A AU57990/98 A AU 57990/98A AU 5799098 A AU5799098 A AU 5799098A AU 5799098 A AU5799098 A AU 5799098A
Authority
AU
Australia
Prior art keywords
gabapentin
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU57990/98A
Inventor
Gideon Pilarski
Claude Singer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Pharmaceutical Industries Ltd
Original Assignee
Teva Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharmaceutical Industries Ltd filed Critical Teva Pharmaceutical Industries Ltd
Publication of AU5799098A publication Critical patent/AU5799098A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/38—Separation; Purification; Stabilisation; Use of additives
    • C07C227/40—Separation; Purification
    • C07C227/42—Crystallisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU57990/98A 1996-12-24 1997-12-24 Preparation of gabapentin Abandoned AU5799098A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL119890 1996-12-24
IL11989096A IL119890A (en) 1996-12-24 1996-12-24 Gabapentin form iii and preparation of gabapentin form ii
PCT/US1997/023164 WO1998028255A1 (en) 1996-12-24 1997-12-24 Preparation of gabapentin

Publications (1)

Publication Number Publication Date
AU5799098A true AU5799098A (en) 1998-07-17

Family

ID=11069615

Family Applications (1)

Application Number Title Priority Date Filing Date
AU57990/98A Abandoned AU5799098A (en) 1996-12-24 1997-12-24 Preparation of gabapentin

Country Status (7)

Country Link
EP (1) EP0950044A4 (en)
AU (1) AU5799098A (en)
CA (1) CA2275912A1 (en)
DE (1) DE97954134T1 (en)
ES (1) ES2204362T1 (en)
IL (1) IL119890A (en)
WO (1) WO1998028255A1 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2137137B1 (en) * 1998-05-25 2000-08-16 Medichem Sa NEW POLYMORPH OF UNHYDRATED GABAPENTINE, ITS PROCEDURE FOR OBTAINING AND ITS USE FOR THE OBTAINING OF PHARMACEUTICAL QUALITY GABAPENTINE.
IT1311984B1 (en) 1999-03-26 2002-03-22 Bioindustria Lab Italiano Medi PROCEDURE FOR THE PREPARATION OF GABAPENTIN.
EP1169060B1 (en) 1999-04-09 2005-08-31 Euro-Celtique S.A. Sodium channel blocker compositions and the use thereof
ES2164527B1 (en) * 1999-04-26 2003-04-01 Medichen S A PROCEDURE FOR OBTAINING GABAPENTINA OF PHARMACEUTICAL QUALITY.
US6294198B1 (en) 1999-08-24 2001-09-25 Purepac Pharmaceutical Co. Pharmaceutical tablet formulation containing gabapentin with improved physical and chemical characteristics and method of making the same
EP1384473A1 (en) * 2000-06-16 2004-01-28 Teva Pharmaceutical Industries Ltd. Stable gabapentin containing more than 20 ppm of chlorine ion
AU2001266992B8 (en) * 2000-06-16 2005-12-01 Teva Pharmaceutical Industries Ltd. Stable gabapentin having pH within a controlled range
WO2001097612A1 (en) * 2000-06-16 2001-12-27 Teva Pharmaceutical Industries Ltd. Stable gabapentin containing more than 2o ppm of chlorine ion
EP1430893A1 (en) * 2000-06-16 2004-06-23 Teva Pharmaceutical Industries Ltd. Stable gabapentin containing more than 20 ppm of chloride ion
US7056951B2 (en) 2000-09-26 2006-06-06 Mutual Pharmaceutical Co., Inc. Stable solid dosage forms of amino acids and processes for producing same
IT1319674B1 (en) * 2000-12-01 2003-10-23 Erregierre Spa PROCESS FOR THE PREPARATION OF CYCLOHEXANACETIC ACID1- (AMINOMETHYL).
PT1423168E (en) 2001-09-03 2006-05-31 Newron Pharm Spa PHARMACEUTICAL COMPOSITION WHICH UNDERSTAND GABAPENTINE OR ITS ANALOGUE AND AN X-AMINOAMIDE AND ITS USE AS ANALGESIC
US6800782B2 (en) * 2001-10-09 2004-10-05 Warner-Lambert Co. Anhydrous crystalline forms of gabapentin
US20030158254A1 (en) * 2002-01-24 2003-08-21 Xenoport, Inc. Engineering absorption of therapeutic compounds via colonic transporters
AU2002356424A1 (en) 2002-11-18 2004-06-15 Nicholas Piramal India Limited Improved process for preparation of gabapentin
US7635717B2 (en) 2002-11-20 2009-12-22 Hikal Limited Process for the preparation of amino methyl cyclo alkane acetic acids
WO2004093779A2 (en) * 2003-04-21 2004-11-04 Matrix Laboratories Ltd Process for the preparation of gabapentin form-ii
WO2004093780A2 (en) * 2003-04-21 2004-11-04 Matrix Laboratories Ltd Process for the preparation of gabapentin form-ii
WO2004106281A1 (en) * 2003-05-30 2004-12-09 Ranbaxy Laboratories Limited Crystalline gabapentin
WO2004110981A1 (en) * 2003-06-12 2004-12-23 Matrix Laboratories Ltd A process for the preparation of gabapentin form-ii
WO2004110342A2 (en) * 2003-06-12 2004-12-23 Matrix Laboratories Ltd Novel polymorph of gabapentin and its conversion to gabapentin form-ii
US7169812B2 (en) 2003-07-01 2007-01-30 Medtronic, Inc. Process for producing injectable gabapentin compositions
ITMI20040579A1 (en) 2004-03-25 2004-06-25 Zambon Spa GABAPENTINA PREPARATION PROCESS
GB0415076D0 (en) * 2004-07-05 2004-08-04 Sandoz Ind Products S A Process for the preparation of gabapentin
GB0416228D0 (en) 2004-07-20 2004-08-25 Sandoz Ind Products S A Process for the preparation of gabapentin
WO2008106217A1 (en) * 2007-02-28 2008-09-04 Teva Pharmaceutical Industries Ltd. Preparation of gabapentin by liquid-liquid extraction
WO2009015685A1 (en) 2007-07-27 2009-02-05 Medichem, S.A. Method for preparing polymorph form ii of gabapentin
CN102363598B (en) * 2011-11-25 2014-02-12 浙江精进药业有限公司 Method for preparing high-purity gabapentin
ITMI20131757A1 (en) 2013-10-22 2015-04-23 Zach System Spa GABAPENTINE PREPARATION PROCESS

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2460891C2 (en) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-aminomethyl-1-cycloalkaneacetic acids and their esters, processes for their preparation and medicaments containing these compounds
US4960931A (en) * 1988-05-02 1990-10-02 Warner-Lambert Company Gabapentin mohohydrate and a process for producing the same
DE3928184A1 (en) * 1989-08-25 1991-02-28 Goedecke Ag METHOD FOR PRODUCING CYCLIC AMINO ACID DERIVATIVES AND INTERMEDIATE PRODUCTS

Also Published As

Publication number Publication date
IL119890A0 (en) 1997-03-18
DE97954134T1 (en) 2004-04-15
WO1998028255A1 (en) 1998-07-02
ES2204362T1 (en) 2004-05-01
EP0950044A1 (en) 1999-10-20
EP0950044A4 (en) 2003-03-26
CA2275912A1 (en) 1998-07-02
IL119890A (en) 2002-03-10

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