AU5695594A - Thio- and oxo-azasteroids, processes for the preparation thereof, use thereof as antiandrogens and pharmaceutical compositions containing them - Google Patents

Thio- and oxo-azasteroids, processes for the preparation thereof, use thereof as antiandrogens and pharmaceutical compositions containing them

Info

Publication number
AU5695594A
AU5695594A AU56955/94A AU5695594A AU5695594A AU 5695594 A AU5695594 A AU 5695594A AU 56955/94 A AU56955/94 A AU 56955/94A AU 5695594 A AU5695594 A AU 5695594A AU 5695594 A AU5695594 A AU 5695594A
Authority
AU
Australia
Prior art keywords
azasteroids
antiandrogens
thio
oxo
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU56955/94A
Inventor
Germano Coppi
Roberto Girardello
Paride Grisenti
Ambrogio Magni
Stefano Poli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Poli Industria Chimica SpA
Original Assignee
Poli Industria Chimica SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT002801 external-priority patent/IT1256635B/en
Priority claimed from IT93MI001730A external-priority patent/IT1264535B1/en
Application filed by Poli Industria Chimica SpA filed Critical Poli Industria Chimica SpA
Publication of AU5695594A publication Critical patent/AU5695594A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/16—Benz[e]indenes; Hydrogenated benz[e]indenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
AU56955/94A 1992-12-10 1993-12-03 Thio- and oxo-azasteroids, processes for the preparation thereof, use thereof as antiandrogens and pharmaceutical compositions containing them Abandoned AU5695594A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IT002801 IT1256635B (en) 1992-12-10 1992-12-10 New 3-(thi)-oxo-4-aza-androstane derivs - used as testosterone 5-alpha-reductase inhibitors for treating super-androgenic conditions e.g. acne or prostate carcinoma.
ITMI92A2801 1992-12-10
IT93MI001730A IT1264535B1 (en) 1993-07-30 1993-07-30 Thioazasteroids, their use as antiandrogens and pharmaceutical compositions containing them
ITMI93A1730 1993-07-30
PCT/EP1993/003400 WO1994013691A1 (en) 1992-12-10 1993-12-03 Thio- and oxo-azasteroids, processes for the preparation thereof, use thereof as antiandrogens and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
AU5695594A true AU5695594A (en) 1994-07-04

Family

ID=26330938

Family Applications (1)

Application Number Title Priority Date Filing Date
AU56955/94A Abandoned AU5695594A (en) 1992-12-10 1993-12-03 Thio- and oxo-azasteroids, processes for the preparation thereof, use thereof as antiandrogens and pharmaceutical compositions containing them

Country Status (4)

Country Link
AU (1) AU5695594A (en)
IL (1) IL107903A0 (en)
MX (1) MX9307794A (en)
WO (1) WO1994013691A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU675225B2 (en) * 1992-05-20 1997-01-30 Merck & Co., Inc. 17-amino substituted 4-azasteroid 5alpha-reductase inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU527030B2 (en) * 1978-04-13 1983-02-10 Merck & Co., Inc. 4-aza-17-substituted-5a-androstan-3-ones

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU675225B2 (en) * 1992-05-20 1997-01-30 Merck & Co., Inc. 17-amino substituted 4-azasteroid 5alpha-reductase inhibitors

Also Published As

Publication number Publication date
MX9307794A (en) 1994-07-29
IL107903A0 (en) 1994-04-12
WO1994013691A1 (en) 1994-06-23

Similar Documents

Publication Publication Date Title
IL112193A0 (en) Phenylpyrazolopyridine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
IL96019A0 (en) Imidazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL106600A (en) Peptides, pharmaceutical compositions containing the same and processes for the preparation thereof
IL109568A0 (en) Urea derivatives, pharmaceutical compositions containing the same and processes for the preparation thereof
IL111533A0 (en) Quinoxalinedione derivatives, methods for the preparation thereof and pharmaceutical compositions containing the same
AU631169B2 (en) Thiazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same
AU2974189A (en) Pharmaceutical compositions containing lactams, new substituted lactams and processes for the preparation thereof
IL105348A0 (en) Azabicyclo derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
AU8245087A (en) New pyrrolobenzimidazoles, processes for the preparation thereof and pharmaceutical compositions containing them
IL92425A0 (en) Alpha-d-glucofuranose derivatives,pharmaceutical compositions containing the same and processes for the preparation thereof
AU2837089A (en) New indolylpiperidine compounds, processes for the preparation thereof and pharmaceutical composition comprising the same
GB8917687D0 (en) Aminopiperazine derivatives,processes for preparation thereof and pharmaceutical composition comprising the same
IL107358A0 (en) a-Phosphonosulfonate derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same
IL115272A0 (en) Asp-pallidipin pharmaceutical compositions containing the same and processes for the preparation thereof
IL87563A0 (en) Isoxazole-beta-carboline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
ZA941088B (en) Substituted ketophosphonates the processes for their preparation and pharmaceutical compositions containing them
GB9310075D0 (en) New mercapto-amide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same
IL102116A0 (en) Hetaryloxy-beta-carboline derivatives,processes for the preparation thereof,and pharmaceutical compositions containing the same
AU3010589A (en) Trisubstituted amines, processes for the preparation thereof and pharmaceutical compositions containing them
AU5695594A (en) Thio- and oxo-azasteroids, processes for the preparation thereof, use thereof as antiandrogens and pharmaceutical compositions containing them
IL90191A0 (en) 3-pyrrolidinylthio-1-azabicyclo-(3.2.0)hept-2-ene-2-carboxylic acid derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
AU1482292A (en) Pharmaceutical composition and process for the preparation thereof
IL101566A0 (en) Isoxazolylimidazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
IL107359A0 (en) Cephem derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
AU584266B2 (en) Azoniaspironortropanol esters, processes for the preparation thereof and pharmaceutical compositions containing them