AU5369996A - Monoclonal antibody against human receptor protein 4-1bb and methods of its use for treatment of diseases - Google Patents

Monoclonal antibody against human receptor protein 4-1bb and methods of its use for treatment of diseases

Info

Publication number
AU5369996A
AU5369996A AU53699/96A AU5369996A AU5369996A AU 5369996 A AU5369996 A AU 5369996A AU 53699/96 A AU53699/96 A AU 53699/96A AU 5369996 A AU5369996 A AU 5369996A AU 5369996 A AU5369996 A AU 5369996A
Authority
AU
Australia
Prior art keywords
diseases
treatment
methods
monoclonal antibody
antibody against
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU53699/96A
Inventor
Chang-Yuil Kang
Byoung S. Kwon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Indiana University Foundation
Original Assignee
Indiana University Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indiana University Foundation filed Critical Indiana University Foundation
Publication of AU5369996A publication Critical patent/AU5369996A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AU53699/96A 1995-03-23 1996-03-22 Monoclonal antibody against human receptor protein 4-1bb and methods of its use for treatment of diseases Abandoned AU5369996A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40985195A 1995-03-23 1995-03-23
US409851 1995-03-23
PCT/US1996/003965 WO1996029348A1 (en) 1995-03-23 1996-03-22 Monoclonal antibody against human receptor protein 4-1bb and methods of its use for treatment of diseases

Publications (1)

Publication Number Publication Date
AU5369996A true AU5369996A (en) 1996-10-08

Family

ID=23622245

Family Applications (1)

Application Number Title Priority Date Filing Date
AU53699/96A Abandoned AU5369996A (en) 1995-03-23 1996-03-22 Monoclonal antibody against human receptor protein 4-1bb and methods of its use for treatment of diseases

Country Status (2)

Country Link
AU (1) AU5369996A (en)
WO (1) WO1996029348A1 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6362325B1 (en) 1988-11-07 2002-03-26 Advanced Research And Technology Institute, Inc. Murine 4-1BB gene
US6303121B1 (en) * 1992-07-30 2001-10-16 Advanced Research And Technology Method of using human receptor protein 4-1BB
IL129138A0 (en) * 1996-10-11 2000-02-17 Bristol Myers Squibb Co Methods and compositions for immunomodulation
KR20000034847A (en) * 1998-11-17 2000-06-26 성재갑 Humanized Antibody Specific for Human 4-1BB Molecule and Pharmaceutical Composition Comprising Same
AU784634B2 (en) 1999-11-30 2006-05-18 Mayo Foundation For Medical Education And Research B7-H1, a novel immunoregulatory molecule
KR100468321B1 (en) * 2001-02-08 2005-01-27 학교법인 울산공업학원 Polypeptides for treatment of cancers and AIDS
AU2002364935A1 (en) 2001-10-09 2003-06-23 Mayo Foundation For Medical Education And Research Enhancement of immune responses by 4-1bb-binding agents
KR100452954B1 (en) * 2002-02-26 2004-10-14 주식회사 엘지생명과학 Manufacturing Method of Enhancing binding affinity of Humanized antibody specific for human 4-1BB molecule through modifying amino acid substitutions in variable region
WO2004055513A2 (en) * 2002-12-16 2004-07-01 Herbert Schwarz Use of cd137 antagonists for the treatment of tumors
US7288638B2 (en) 2003-10-10 2007-10-30 Bristol-Myers Squibb Company Fully human antibodies against human 4-1BB
AR046094A1 (en) * 2003-10-10 2005-11-23 Bristol Myers Squibb Co COMPLETELY HUMAN ANTIBODIES AGAINST HUMAN 4-1BB
HUE039237T2 (en) 2004-10-06 2018-12-28 Mayo Found Medical Education & Res B7-h1 and pd-1 in treatment of renal cell carcinoma
WO2010042433A1 (en) 2008-10-06 2010-04-15 Bristol-Myers Squibb Company Combination of cd137 antibody and ctla-4 antibody for the treatment of proliferative diseases
SG10201506906VA (en) 2010-09-09 2015-10-29 Pfizer 4-1bb binding molecules
US9302005B2 (en) 2013-03-14 2016-04-05 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
ES2714708T3 (en) 2013-10-01 2019-05-29 Mayo Found Medical Education & Res Procedures for the treatment of cancer in patients with elevated levels of Bim
US10302653B2 (en) 2014-05-22 2019-05-28 Mayo Foundation For Medical Education And Research Distinguishing antagonistic and agonistic anti B7-H1 antibodies
US10517875B2 (en) 2014-07-23 2019-12-31 Mayo Foundation for Medical Engineering and Research Targeting DNA-PKcs and B7-H1 to treat cancer
WO2017075045A2 (en) 2015-10-30 2017-05-04 Mayo Foundation For Medical Education And Research Antibodies to b7-h1
WO2018134787A2 (en) 2017-01-20 2018-07-26 Magenta Therapeutics, Inc. Compositions and methods for the depletion of cd137+ cells
WO2019141268A1 (en) * 2018-01-22 2019-07-25 江苏恒瑞医药股份有限公司 Anti-4-1bb antibody, antigen-binding fragment thereof and medical use thereof
CA3169910A1 (en) 2020-02-28 2021-09-02 Shanghai Henlius Biotech, Inc. Anti-cd137 constructs, multispecific antibody and uses thereof
CA3169939A1 (en) 2020-02-28 2021-09-02 Jie Xue Anti-cd137 construct and use thereof

Also Published As

Publication number Publication date
WO1996029348A1 (en) 1996-09-26

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