AU531507B2 - 8-substituted 7-phenyl-1,2,4-triazolo(4,3-c) pyrimidines -5-amines and amides - Google Patents

8-substituted 7-phenyl-1,2,4-triazolo(4,3-c) pyrimidines -5-amines and amides

Info

Publication number
AU531507B2
AU531507B2 AU61153/80A AU6115380A AU531507B2 AU 531507 B2 AU531507 B2 AU 531507B2 AU 61153/80 A AU61153/80 A AU 61153/80A AU 6115380 A AU6115380 A AU 6115380A AU 531507 B2 AU531507 B2 AU 531507B2
Authority
AU
Australia
Prior art keywords
triazolo
pyrimidines
amides
amines
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU61153/80A
Other languages
English (en)
Other versions
AU6115380A (en
Inventor
Hans A. Wagner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of AU6115380A publication Critical patent/AU6115380A/en
Application granted granted Critical
Publication of AU531507B2 publication Critical patent/AU531507B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU61153/80A 1979-08-08 1980-08-07 8-substituted 7-phenyl-1,2,4-triazolo(4,3-c) pyrimidines -5-amines and amides Ceased AU531507B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6470779A 1979-08-08 1979-08-08
US064707 1979-08-08

Publications (2)

Publication Number Publication Date
AU6115380A AU6115380A (en) 1981-02-12
AU531507B2 true AU531507B2 (en) 1983-08-25

Family

ID=22057763

Family Applications (1)

Application Number Title Priority Date Filing Date
AU61153/80A Ceased AU531507B2 (en) 1979-08-08 1980-08-07 8-substituted 7-phenyl-1,2,4-triazolo(4,3-c) pyrimidines -5-amines and amides

Country Status (7)

Country Link
JP (1) JPS5632479A (cs)
AU (1) AU531507B2 (cs)
CA (2) CA1246063B (cs)
CH (1) CH645898A5 (cs)
DE (1) DE3029871C2 (cs)
FR (1) FR2463143A1 (cs)
GB (1) GB2056449A (cs)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU622963B2 (en) * 1988-12-22 1992-04-30 G.D. Searle & Co. Diol metabolites of 7-phenyl-1,2,4-triazolo(2,3-C)pyrimidines-5-amines

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2056449A (en) 1979-08-08 1981-03-18 Searle & Co 8-substituted-7-phenyl-1,2,4- triazolo[4,3-c] pyrimidine-5-amines and amides
DK135184A (da) * 1983-03-03 1984-10-10 Riker Laboratories Inc Triazol(4,3-c)- og triazol(1,5-c)pyrimidiner
US4532242A (en) * 1983-05-02 1985-07-30 Riker Laboratories, Inc. Substituted triazolo[4,3-c]pyrimidines
US4528288A (en) * 1983-05-02 1985-07-09 Riker Laboratories, Inc. Substituted triazolo[1,5-c]pyrimidines
US4483987A (en) * 1983-06-20 1984-11-20 G. D. Searle & Co. 8-Substituted 7-phenyl-1,2,4-triazolo[2,3-c]pyrimidines-5-amines and amides
TW440563B (en) * 1996-05-23 2001-06-16 Hoffmann La Roche Aryl pyrimidine derivatives and a pharmaceutical composition thereof
US5952331A (en) * 1996-05-23 1999-09-14 Syntex (Usa) Inc. Aryl pyrimidine derivatives
US5958934A (en) * 1996-05-23 1999-09-28 Syntex (U.S.A.) Inc. Aryl pyrimidine derivatives and uses thereof
JP2014500254A (ja) 2010-11-09 2014-01-09 セルゾーム リミティッド Ｔｙｋ２阻害剤としてのピリジン化合物およびそのアザ類似体
CN113692306B (zh) * 2019-04-03 2024-06-21 泰拉强石株式会社 基于胸腺嘧啶核酸碱基的三唑并嘧啶类及其制造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1205144A (fr) * 1957-06-14 1960-01-29 Farmaceutici Italia Procédé pour la synthèse de 7-méthyl-s. triazol (4, 3-c) pyrimidines substituéesen position 5
US3284542A (en) 1963-03-22 1966-11-08 Rexall Drug Chemical Preparation of high impact compositions from vinyl aromatic monomers and rubbery diolefin polymers
US3244715A (en) 1964-10-30 1966-04-05 Smith Kline French Lab Phenylimidazo [4, 5-d] pyridazines
US3461123A (en) 1968-04-12 1969-08-12 Merck & Co Inc 1h-imidazo(4,5-b)pyrazin-2-ones and processes for their preparation
GB2056449A (en) 1979-08-08 1981-03-18 Searle & Co 8-substituted-7-phenyl-1,2,4- triazolo[4,3-c] pyrimidine-5-amines and amides

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU622963B2 (en) * 1988-12-22 1992-04-30 G.D. Searle & Co. Diol metabolites of 7-phenyl-1,2,4-triazolo(2,3-C)pyrimidines-5-amines

Also Published As

Publication number Publication date
CH645898A5 (de) 1984-10-31
DE3029871C2 (de) 1987-01-15
DE3029871A1 (de) 1981-02-26
CA1246063A (en) 1988-12-06
FR2463143B1 (cs) 1983-12-16
JPH029592B2 (cs) 1990-03-02
AU6115380A (en) 1981-02-12
JPS5632479A (en) 1981-04-01
CA1246064A (en) 1988-12-06
CA1246063B (en) 1988-12-06
GB2056449A (en) 1981-03-18
CA1246064B (en) 1988-12-06
FR2463143A1 (fr) 1981-02-20

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