AU5295899A - Hydroxamic acid derivatives as inhibitors of beta-amyloid production - Google Patents

Hydroxamic acid derivatives as inhibitors of beta-amyloid production

Info

Publication number
AU5295899A
AU5295899A AU52958/99A AU5295899A AU5295899A AU 5295899 A AU5295899 A AU 5295899A AU 52958/99 A AU52958/99 A AU 52958/99A AU 5295899 A AU5295899 A AU 5295899A AU 5295899 A AU5295899 A AU 5295899A
Authority
AU
Australia
Prior art keywords
inhibitors
beta
acid derivatives
hydroxamic acid
amyloid production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU52958/99A
Inventor
Andrew Paul Ayscough
Mandy Johnstone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vernalis R&D Ltd
Original Assignee
British Biotech Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Biotech Pharmaceuticals Ltd filed Critical British Biotech Pharmaceuticals Ltd
Publication of AU5295899A publication Critical patent/AU5295899A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU52958/99A 1998-08-11 1999-08-10 Hydroxamic acid derivatives as inhibitors of beta-amyloid production Abandoned AU5295899A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9817348.7A GB9817348D0 (en) 1998-08-11 1998-08-11 Pharmaceutical use of esters
GB9817348 1998-08-11
PCT/GB1999/002626 WO2000009119A1 (en) 1998-08-11 1999-08-10 Hydroxamic acid derivatives as inhibitors of beta-amyloid production

Publications (1)

Publication Number Publication Date
AU5295899A true AU5295899A (en) 2000-03-06

Family

ID=10836978

Family Applications (1)

Application Number Title Priority Date Filing Date
AU52958/99A Abandoned AU5295899A (en) 1998-08-11 1999-08-10 Hydroxamic acid derivatives as inhibitors of beta-amyloid production

Country Status (5)

Country Link
EP (1) EP1105116A1 (en)
JP (1) JP2002522489A (en)
AU (1) AU5295899A (en)
GB (1) GB9817348D0 (en)
WO (1) WO2000009119A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10043282A1 (en) * 2000-09-02 2002-03-28 Kurt Heininger Medicaments containing amyloid-beta-protein formation and/or secretion inhibitors, are used for treating hypertension, diabetes, arteriosclerosis, rheumatism, cardiac infarction, inflammation or sepsis
NZ594561A (en) * 2009-03-19 2013-03-28 Bristol Myers Squibb Co A novel alpha-(n-sulfonamido)acetamide compound as an inhibitor of beta amyloid peptide production
US20200121666A1 (en) * 2017-06-05 2020-04-23 The Methodist Hospital System Tau phosphorylation inhibitors and methods for treating or preventing alzheimer's disease

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0925278B1 (en) * 1996-09-10 2002-07-17 British Biotech Pharmaceuticals Limited Cytostatic hydroxamic acid derivatives

Also Published As

Publication number Publication date
JP2002522489A (en) 2002-07-23
EP1105116A1 (en) 2001-06-13
WO2000009119A1 (en) 2000-02-24
GB9817348D0 (en) 1998-10-07

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase