AU520583B2 - Purine bronchodilators - Google Patents

Purine bronchodilators

Info

Publication number
AU520583B2
AU520583B2 AU61021/80A AU6102180A AU520583B2 AU 520583 B2 AU520583 B2 AU 520583B2 AU 61021/80 A AU61021/80 A AU 61021/80A AU 6102180 A AU6102180 A AU 6102180A AU 520583 B2 AU520583 B2 AU 520583B2
Authority
AU
Australia
Prior art keywords
bronchodilators
purine
purine bronchodilators
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
AU61021/80A
Other languages
English (en)
Other versions
AU6102180A (en
Inventor
Takayuki Naito
Susumu Nakagawa
Takaaki Okita
Haruhiro Yamahita
Tetsuro Yamasaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of AU6102180A publication Critical patent/AU6102180A/en
Application granted granted Critical
Publication of AU520583B2 publication Critical patent/AU520583B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU61021/80A 1979-08-06 1980-08-01 Purine bronchodilators Expired - Fee Related AU520583B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US64240 1979-08-06
US06/064,240 US4241063A (en) 1979-08-06 1979-08-06 Purine derivatives and their use as bronchodilators
US74848 1979-09-13
US74849 1979-09-13

Publications (2)

Publication Number Publication Date
AU6102180A AU6102180A (en) 1981-02-12
AU520583B2 true AU520583B2 (en) 1982-02-11

Family

ID=22054538

Family Applications (1)

Application Number Title Priority Date Filing Date
AU61021/80A Expired - Fee Related AU520583B2 (en) 1979-08-06 1980-08-01 Purine bronchodilators

Country Status (5)

Country Link
US (1) US4241063A (en, 2012)
JP (1) JPS57163382A (en, 2012)
AU (1) AU520583B2 (en, 2012)
BE (1) BE884653A (en, 2012)
ZA (1) ZA804701B (en, 2012)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4743689A (en) * 1984-11-20 1988-05-10 Nippon Kayaku Kabushiki Kaisha Antibiotic derivative of adenine
DE3529497A1 (de) * 1985-08-17 1987-02-26 Boehringer Mannheim Gmbh N(pfeil hoch)6(pfeil hoch)-disubstituierte purinderivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
US4916225A (en) * 1986-11-25 1990-04-10 Institut Organicheskogo Sinteza Akademii Nauk Latviiskoi Ssr 9-substituted guanines
GB9312853D0 (en) * 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5922751A (en) * 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
US5591776A (en) * 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
AU695032B2 (en) * 1994-10-05 1998-08-06 Darwin Discovery Limited Purine and guanine compounds as inhibitors of PNP
US6166041A (en) * 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
US6075016A (en) * 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US6294541B1 (en) 1996-06-06 2001-09-25 Euro-Celtique S.A. Purine derivatives having phosphodiesterase IV inhibition activity
US5864037A (en) * 1996-06-06 1999-01-26 Euro-Celtique, S.A. Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
US6057445A (en) 1997-12-12 2000-05-02 Euro-Celtique S.A. Purine compounds having PDE IV inhibitory activity and methods of synthesis
US6319928B1 (en) 1998-11-30 2001-11-20 Euro-Celtique, S.A. Purine derivatives having phosphodiesterase IV inhibition activity
JP2002541078A (ja) 1999-04-02 2002-12-03 ユーロ−セルティーク，エス．エー． ホスホジエステラーゼｉｖ阻害活性を有するプリン誘導体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3228937A (en) * 1963-07-17 1966-01-11 Shell Oil Co Adenine derivative
US3930005A (en) * 1973-06-15 1975-12-30 Squibb & Sons Inc Antiinflammatory agents and their use
US3862189A (en) * 1973-08-14 1975-01-21 Warner Lambert Co Aralkyl-substituted purines and pyrimidines as antianginal bronchodilator agents
US3917837A (en) * 1974-10-21 1975-11-04 American Cyanamid Co Method of using trans-2-(6-amino-9H-purin-9-yl)-cyclopentanol
JPS5271492A (en) * 1975-12-10 1977-06-14 Kohjin Co Ltd Synthesis of 9-substituted-2-substituted thioadenines

Also Published As

Publication number Publication date
BE884653A (fr) 1981-02-06
JPH0222075B2 (en, 2012) 1990-05-17
JPS57163382A (en) 1982-10-07
AU6102180A (en) 1981-02-12
US4241063A (en) 1980-12-23
ZA804701B (en) 1981-10-28

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