AU5125298A - Bicistronic recombinant viruses useful for the treatment of dyslipoproteinemia-related pathologies - Google Patents
Bicistronic recombinant viruses useful for the treatment of dyslipoproteinemia-related pathologiesInfo
- Publication number
- AU5125298A AU5125298A AU51252/98A AU5125298A AU5125298A AU 5125298 A AU5125298 A AU 5125298A AU 51252/98 A AU51252/98 A AU 51252/98A AU 5125298 A AU5125298 A AU 5125298A AU 5125298 A AU5125298 A AU 5125298A
- Authority
- AU
- Australia
- Prior art keywords
- dyslipoproteinemia
- treatment
- recombinant viruses
- related pathologies
- viruses useful
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
- C12N9/20—Triglyceride splitting, e.g. by means of lipase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
- C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR96/13969 | 1996-11-15 | ||
FR9613969A FR2755975B1 (en) | 1996-11-15 | 1996-11-15 | BICISTRONIC RECOMBINANT VIRUSES USEFUL FOR THE TREATMENT OF DYSLIPOPROTEINEMIA-RELATED CONDITIONS |
PCT/FR1997/002043 WO1998022606A1 (en) | 1996-11-15 | 1997-11-13 | Recombinant bicistron adenovirus for treating pathological conditions linked with dyslipoproteinemia |
Publications (2)
Publication Number | Publication Date |
---|---|
AU5125298A true AU5125298A (en) | 1998-06-10 |
AU721654B2 AU721654B2 (en) | 2000-07-13 |
Family
ID=9497670
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU51252/98A Ceased AU721654B2 (en) | 1996-11-15 | 1997-11-13 | Bicistronic recombinant viruses useful for the treatment of dyslipoproteinemia-related pathologies |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0941355A1 (en) |
JP (1) | JP2001506488A (en) |
KR (1) | KR20000053320A (en) |
AU (1) | AU721654B2 (en) |
BR (1) | BR9712957A (en) |
CA (1) | CA2271437A1 (en) |
CZ (1) | CZ170399A3 (en) |
FR (1) | FR2755975B1 (en) |
HU (1) | HUP9904500A3 (en) |
IL (1) | IL129823A0 (en) |
NO (1) | NO992260D0 (en) |
SK (1) | SK63499A3 (en) |
WO (1) | WO1998022606A1 (en) |
ZA (1) | ZA9710271B (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1064392A2 (en) * | 1998-03-16 | 2001-01-03 | Introgen Therapeutics, Inc. | Multigene vectors |
WO2001011063A2 (en) * | 1999-08-10 | 2001-02-15 | Develogen Ag Für Entwicklungsbiologische Forschung | Gene transfer combination vectors, method for the production and utilization thereof |
FR2799472B1 (en) * | 1999-10-07 | 2004-07-16 | Aventis Pharma Sa | PREPARATION OF RECOMBINANT ADENOVIRUSES AND ADENOVIRAL BANKS |
AU2001247648B2 (en) * | 2000-03-24 | 2006-03-30 | Cold Genesys, Inc. | Cell-specific adenovirus vectors comprising an internal ribosome entry site |
US6544780B1 (en) | 2000-06-02 | 2003-04-08 | Genphar, Inc. | Adenovirus vector with multiple expression cassettes |
US7179659B2 (en) | 2001-04-02 | 2007-02-20 | Agilent Technologies, Inc. | Sensor surfaces for detecting analytes and methods of use |
ES2734221T3 (en) * | 2011-08-08 | 2019-12-04 | Allergan Pharmaceuticals Int Ltd | Method for dissolution test of solid compositions containing digestive enzymes |
JP7316711B2 (en) * | 2019-08-19 | 2023-07-28 | ナンジン・ノベル・バイオテクノロジー・カンパニー・リミテッド | A replicating oncolytic adenovirus that regulates lipid metabolism and its application |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2114416C (en) * | 1991-08-07 | 1998-07-07 | W. French Anderson | Retroviral vectors containing internal ribosome entry sites |
GB9125896D0 (en) * | 1991-12-05 | 1992-02-05 | Almond Jeffrey W | Bicistronic viruses |
FR2704556B1 (en) * | 1993-04-30 | 1995-07-13 | Rhone Poulenc Rorer Sa | Recombinant viruses and their use in gene therapy. |
FR2722208B1 (en) * | 1994-07-05 | 1996-10-04 | Inst Nat Sante Rech Med | NEW INTERNAL RIBOSOME ENTRY SITE, VECTOR CONTAINING SAME AND THERAPEUTIC USE |
EP0787200B1 (en) * | 1994-10-28 | 2005-04-20 | The Trustees Of The University Of Pennsylvania | Improved adenovirus and methods of use thereof |
FR2731710B1 (en) * | 1995-03-14 | 1997-04-30 | Rhone Poulenc Rorer Sa | RECOMBINANT VIRUSES EXPRESSING LECITHIN CHOLESTEROL ACYLTRANSFERASE AND USES IN GENE THERAPY |
-
1996
- 1996-11-15 FR FR9613969A patent/FR2755975B1/en not_active Expired - Fee Related
-
1997
- 1997-11-13 WO PCT/FR1997/002043 patent/WO1998022606A1/en not_active Application Discontinuation
- 1997-11-13 CA CA002271437A patent/CA2271437A1/en not_active Abandoned
- 1997-11-13 AU AU51252/98A patent/AU721654B2/en not_active Ceased
- 1997-11-13 IL IL12982397A patent/IL129823A0/en unknown
- 1997-11-13 KR KR1019990704322A patent/KR20000053320A/en not_active Application Discontinuation
- 1997-11-13 CZ CZ991703A patent/CZ170399A3/en unknown
- 1997-11-13 BR BR9712957-7A patent/BR9712957A/en not_active Application Discontinuation
- 1997-11-13 SK SK634-99A patent/SK63499A3/en unknown
- 1997-11-13 HU HU9904500A patent/HUP9904500A3/en unknown
- 1997-11-13 JP JP52326398A patent/JP2001506488A/en active Pending
- 1997-11-13 EP EP97945922A patent/EP0941355A1/en not_active Withdrawn
- 1997-11-13 ZA ZA9710271A patent/ZA9710271B/en unknown
-
1999
- 1999-05-10 NO NO992260A patent/NO992260D0/en unknown
Also Published As
Publication number | Publication date |
---|---|
FR2755975B1 (en) | 1999-05-07 |
AU721654B2 (en) | 2000-07-13 |
CZ170399A3 (en) | 1999-08-11 |
FR2755975A1 (en) | 1998-05-22 |
JP2001506488A (en) | 2001-05-22 |
EP0941355A1 (en) | 1999-09-15 |
BR9712957A (en) | 2000-02-01 |
KR20000053320A (en) | 2000-08-25 |
WO1998022606A1 (en) | 1998-05-28 |
CA2271437A1 (en) | 1998-05-28 |
NO992260L (en) | 1999-05-10 |
ZA9710271B (en) | 1998-08-21 |
NO992260D0 (en) | 1999-05-10 |
HUP9904500A3 (en) | 2002-01-28 |
IL129823A0 (en) | 2000-02-29 |
SK63499A3 (en) | 2000-05-16 |
HUP9904500A2 (en) | 2000-05-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FGA | Letters patent sealed or granted (standard patent) |