AU4965796A - Self-renewing pluripotent hematopoietic stem cell compositions, methods of use, and culture systems therefor - Google Patents

Self-renewing pluripotent hematopoietic stem cell compositions, methods of use, and culture systems therefor

Info

Publication number
AU4965796A
AU4965796A AU49657/96A AU4965796A AU4965796A AU 4965796 A AU4965796 A AU 4965796A AU 49657/96 A AU49657/96 A AU 49657/96A AU 4965796 A AU4965796 A AU 4965796A AU 4965796 A AU4965796 A AU 4965796A
Authority
AU
Australia
Prior art keywords
self
methods
stem cell
hematopoietic stem
culture systems
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU49657/96A
Inventor
Ronald Palacios
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Texas System
Original Assignee
University of Texas System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Texas System filed Critical University of Texas System
Publication of AU4965796A publication Critical patent/AU4965796A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/14—Coculture with; Conditioned medium produced by hepatocytes
AU49657/96A 1995-01-24 1996-01-24 Self-renewing pluripotent hematopoietic stem cell compositions, methods of use, and culture systems therefor Abandoned AU4965796A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US37814495A 1995-01-24 1995-01-24
US378144 1995-01-24
US46210895A 1995-06-05 1995-06-05
US462108 1995-06-05
PCT/US1996/000994 WO1996022693A1 (en) 1995-01-24 1996-01-24 Self-renewing pluripotent hematopoietic stem cell compositions, methods of use, and culture systems therefor

Publications (1)

Publication Number Publication Date
AU4965796A true AU4965796A (en) 1996-08-14

Family

ID=27008089

Family Applications (1)

Application Number Title Priority Date Filing Date
AU49657/96A Abandoned AU4965796A (en) 1995-01-24 1996-01-24 Self-renewing pluripotent hematopoietic stem cell compositions, methods of use, and culture systems therefor

Country Status (2)

Country Link
AU (1) AU4965796A (en)
WO (1) WO1996022693A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999036441A2 (en) * 1998-01-17 1999-07-22 Telistar International Haemopoietic stem cell inhibitor(s)
US6632620B1 (en) 2000-06-22 2003-10-14 Andrew N. Makarovskiy Compositions for identification and isolation of stem cells
GB0202149D0 (en) 2002-01-30 2002-03-20 Univ Edinburgh Pluripotency determining factors and uses thereof

Also Published As

Publication number Publication date
WO1996022693A1 (en) 1996-08-01

Similar Documents

Publication Publication Date Title
AU9582398A (en) Methods and devices for the long-term culture of hematopoietic progenitor cells
AU6125596A (en) Method of expanding hematopoietic stem cells, reagents and ioreactors for use therein
AU1119397A (en) Ex vivo culture of stem cells
AU3783993A (en) Culturing of hematopoietic stem cells and their genetic engineering
AU1644295A (en) Cell culture substrates and methods of use
AU2260097A (en) Hematopoietic cell culture nutrient supplement
AU4336599A (en) (in vitro) maintenance of hematopoietic stem cells
AU8128094A (en) (in vitro) amplification of stem cells
AU4330597A (en) Serum-free mammalian cell culture medium, and uses thereof
AU5886000A (en) Compositions, kits, and methods for modulating survival and differentiation of multi-potential hematopoietic progenitor cells
AU4370096A (en) Hydrocarbyl containing coatings, compositions and methods of use
AU7832194A (en) Gas permeable bioreactor and method of use
AU2730497A (en) Cryopreservation and extensive subculturing of human mesenchymal stem cells
AU7213294A (en) Methods of culturing and modulating the growth of hair follicular stem cells
AU5566396A (en) Manipulation of plant cell and tissue cultures
AU1952597A (en) Combinations, having immunosuppressive effects, containing cyclooxygenase-2 inhibitor and a leukotriene a4 hydrolase inhibitor
AU6125396A (en) Serum-free media for primitive hematopoietic cells and metho ds of use thereof
AU2387795A (en) Culture medium for maintaining viability of mammalian cells
EP0567886A3 (en) Coating composition for culturing animal adhesive cells and method for culturing of the cells in serum-free condition.
AU3392697A (en) (in vitro) derivation and culture of primate pluripotent stem cells and therapeutic uses thereof
AU3542295A (en) A method of selecting pluripotent hematopoietic progenitor cells
AU9508998A (en) Methods and compositions for binding hematopoietic stem cells
EP0682106A3 (en) Liver parenchymal cells having clonal growth ability, method for obtaining same, method for culturing same, and culturing system of primary hepatocytes
AU7603096A (en) Methods of assessing viability of microbial cultures
AU4965796A (en) Self-renewing pluripotent hematopoietic stem cell compositions, methods of use, and culture systems therefor