AU4867497A - 1-(4-piperdinyl)-piperidinylene as aggregation inhibitor - Google Patents

1-(4-piperdinyl)-piperidinylene as aggregation inhibitor

Info

Publication number
AU4867497A
AU4867497A AU48674/97A AU4867497A AU4867497A AU 4867497 A AU4867497 A AU 4867497A AU 48674/97 A AU48674/97 A AU 48674/97A AU 4867497 A AU4867497 A AU 4867497A AU 4867497 A AU4867497 A AU 4867497A
Authority
AU
Australia
Prior art keywords
piperidinylene
piperdinyl
aggregation inhibitor
aggregation
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU48674/97A
Inventor
Volkhard Austel
Brian Guth
Frank Himmelsbach
Gunter Linz
Helmut Pieper
Johannes Weisenberger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of AU4867497A publication Critical patent/AU4867497A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU48674/97A 1996-10-21 1997-10-15 1-(4-piperdinyl)-piperidinylene as aggregation inhibitor Abandoned AU4867497A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE1996143331 DE19643331A1 (en) 1996-10-21 1996-10-21 1- (4-Piperidinyl) -piperidinylenes, medicaments containing these compounds, their use and process for their preparation
DE19643331 1996-10-21
PCT/EP1997/005683 WO1998017646A1 (en) 1996-10-21 1997-10-15 1-(4-piperdinyl)-piperidinylene as aggregation inhibitor

Publications (1)

Publication Number Publication Date
AU4867497A true AU4867497A (en) 1998-05-15

Family

ID=7809297

Family Applications (1)

Application Number Title Priority Date Filing Date
AU48674/97A Abandoned AU4867497A (en) 1996-10-21 1997-10-15 1-(4-piperdinyl)-piperidinylene as aggregation inhibitor

Country Status (3)

Country Link
AU (1) AU4867497A (en)
DE (1) DE19643331A1 (en)
WO (1) WO1998017646A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL151164A0 (en) 2000-03-06 2003-04-10 Acadia Pharm Inc Azacyclic compounds for use in the treatment of serotonin related diseases
GB0108876D0 (en) * 2001-04-09 2001-05-30 Novartis Ag Organic Compounds
KR20100008799A (en) 2001-12-28 2010-01-26 아카디아 파마슈티칼스 인코포레이티드 Spiroazacyclic compounds as monoamine receptor modulators
US7538222B2 (en) 2002-06-24 2009-05-26 Acadia Pharmaceuticals, Inc. N-substituted piperidine derivatives as serotonin receptor agents
US7253186B2 (en) 2002-06-24 2007-08-07 Carl-Magnus Andersson N-substituted piperidine derivatives as serotonin receptor agents
AU2003247615B2 (en) 2002-06-24 2007-08-09 Acadia Pharmaceuticals Inc. N-substituted piperidine derivatives as serotonin receptor agents
WO2004009549A2 (en) * 2002-07-18 2004-01-29 Actelion Pharmaceuticals Ltd Piperidines useful for the treatment of central nervous system disorders
CA2512639C (en) 2003-01-16 2012-10-30 Acadia Pharmaceuticals Inc. Selective serotonin 2a/2c receptor inverse agonists as therapeutics for neurodegenerative diseases
US20050261278A1 (en) 2004-05-21 2005-11-24 Weiner David M Selective serotonin receptor inverse agonists as therapeutics for disease
US7820695B2 (en) 2004-05-21 2010-10-26 Acadia Pharmaceuticals, Inc. Selective serotonin receptor inverse agonists as therapeutics for disease
EP2289879B1 (en) 2004-09-27 2014-11-12 Acadia Pharmaceuticals Inc. Synthesis of a crystalline form of n-(4-fluorobenzyl)-n-(1-methylpiperidin-4-yl)-n'-(4-(2-methylpropyloxy)phenylmethyl)carbamide tartrate salt
US7790899B2 (en) 2004-09-27 2010-09-07 Acadia Pharmaceuticals, Inc. Synthesis of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and crystalline forms
WO2008116024A2 (en) 2007-03-19 2008-09-25 Acadia Pharmaceuticals Inc. Combinations of 5-ht2a inverse agonists and antagonists with antipsychotics
PL3325444T3 (en) 2015-07-20 2021-12-06 Acadia Pharmaceuticals Inc. Methods for preparing n-(4-fluorobenzyl)-n-(1-methylpiperidin-4-yl)-n'-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and polymorphic form c
US10953000B2 (en) 2016-03-25 2021-03-23 Acadia Pharmaceuticals Inc. Combination of pimavanserin and cytochrome P450 modulators
WO2017165635A1 (en) 2016-03-25 2017-09-28 Acadia Pharmaceuticals Inc. Combination of pimavanserin and cytochrome p450 modulators
EP3558311A1 (en) 2016-12-20 2019-10-30 Acadia Pharmaceuticals Inc. Pimavanserin alone or in combination for use in the treatment of alzheimer's disease psychosis
US11135211B2 (en) 2017-04-28 2021-10-05 Acadia Pharmaceuticals Inc. Pimavanserin for treating impulse control disorder
US20210077479A1 (en) 2017-08-30 2021-03-18 Acadia Pharmaceuticals Inc. Formulations of pimavanserin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0052311A1 (en) * 1980-11-19 1982-05-26 Sterling Drug Inc. 1-((Benzoylphenyl) - lower-alkyl) piperidines and carbinol analogs and preparation thereof
US4304911A (en) * 1980-11-19 1981-12-08 Sterling Drug Inc. Benzoylphenyl lower alkanoyl piperidines
AU2915892A (en) * 1991-11-14 1993-06-15 Glaxo Group Limited Piperidine acetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation
DE4407961A1 (en) * 1994-03-10 1995-09-14 Thomae Gmbh Dr K Imidazolidin-2-one, medicaments containing these compounds and process for their preparation
CA2200468A1 (en) * 1994-10-27 1996-05-09 Wayne J. Thompson Muscarine antagonists

Also Published As

Publication number Publication date
DE19643331A1 (en) 1998-04-23
WO1998017646A1 (en) 1998-04-30

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