AU4730689A - Microgranulates comprising a saturated fatty acid triglyceride and an active substance, and topical pharmaceutical compositions containing such microgranulates - Google Patents

Microgranulates comprising a saturated fatty acid triglyceride and an active substance, and topical pharmaceutical compositions containing such microgranulates

Info

Publication number
AU4730689A
AU4730689A AU47306/89A AU4730689A AU4730689A AU 4730689 A AU4730689 A AU 4730689A AU 47306/89 A AU47306/89 A AU 47306/89A AU 4730689 A AU4730689 A AU 4730689A AU 4730689 A AU4730689 A AU 4730689A
Authority
AU
Australia
Prior art keywords
microgranulates
fatty acid
saturated fatty
active substance
acid triglyceride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU47306/89A
Other versions
AU617570B2 (en
Inventor
Josiane Allec
Alain Brzokewicz
Jean-Claude Jamoulle
Braham Shroot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Galderma Research and Development SNC
Original Assignee
Centre International de Recherches Dermatologiques Galderma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre International de Recherches Dermatologiques Galderma filed Critical Centre International de Recherches Dermatologiques Galderma
Publication of AU4730689A publication Critical patent/AU4730689A/en
Application granted granted Critical
Publication of AU617570B2 publication Critical patent/AU617570B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241—Containing particulates characterized by their shape and/or structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth

Abstract

Microgranules loaded with a substance which is therapeutically active with respect to skin disorders and which melts on application to the skin. They are essentially formed by granulation of the abovementioned active substance using at least one saturated fatty acid triglyceride having a melting point of between 30 and 50 DEG C, the abovementioned microgranules having an average diameter of between approximately 5 mu m and 800 mu m. These microgranules find application in the treatment of skin disorders.
AU47306/89A 1988-12-29 1989-12-28 Microgranulates comprising a saturated fatty acid triglyceride and an active substance, and topical pharmaceutical compositions containing such microgranulates Ceased AU617570B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU87416 1988-12-29
LU87416A LU87416A1 (en) 1988-12-29 1988-12-29 MICROGRANULES LOADED WITH AN ACTIVE SUBSTANCE, ESSENTIALLY CONSISTING OF A TRIGLYCERIDE OF SATURATED FATTY ACIDS AND THEIR TOPICAL USE IN THE THERAPEUTIC FIELD

Publications (2)

Publication Number Publication Date
AU4730689A true AU4730689A (en) 1990-07-05
AU617570B2 AU617570B2 (en) 1991-11-28

Family

ID=19731128

Family Applications (1)

Application Number Title Priority Date Filing Date
AU47306/89A Ceased AU617570B2 (en) 1988-12-29 1989-12-28 Microgranulates comprising a saturated fatty acid triglyceride and an active substance, and topical pharmaceutical compositions containing such microgranulates

Country Status (16)

Country Link
EP (1) EP0376852B1 (en)
JP (1) JP2731008B2 (en)
KR (1) KR900009058A (en)
AT (1) ATE90869T1 (en)
AU (1) AU617570B2 (en)
CA (1) CA2006834A1 (en)
DE (2) DE376852T1 (en)
DK (1) DK669789A (en)
ES (1) ES2034951T3 (en)
FI (1) FI896321A0 (en)
GR (1) GR910300044T1 (en)
LU (1) LU87416A1 (en)
NO (1) NO895307L (en)
NZ (1) NZ231982A (en)
PT (1) PT92747A (en)
ZA (1) ZA899961B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU697767B2 (en) * 1995-03-17 1998-10-15 Gebro Broschek Gesellschaft M.B.H. Topically applicable pharmaceutical composition, process of manufacture, and use of the composition
US20080166413A1 (en) * 2000-06-26 2008-07-10 Pharmakodex Limited Topical pharmaceutical formulations and methods of treatment

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2649608B1 (en) * 1989-07-12 1991-10-11 Oreal COSMETIC COMPOSITION IN THE FORM OF AN AQUEOUS GEL CONTAINING SUSPENSION SPHEROIDS OF A NON-HYDROPHILIC SOLID LIPID SUBSTANCE
DE4336407A1 (en) * 1993-10-21 1995-04-27 Rotring Int Gmbh Waterproof cosmetics
FR2721210B1 (en) * 1994-06-17 1996-08-02 Oreal Cleaning composition containing lipid grains.
US5540920A (en) * 1994-11-22 1996-07-30 Olin Corporation Synergistic biocide composition containing pyrithione plus an additive
US5679648A (en) * 1994-11-30 1997-10-21 The University Hospital Methods for the treatment and prevention of fungal infections by administration of 3'-deoxypurine nucleosides
DE19511322C2 (en) * 1995-03-28 1999-09-02 Mann Gerhard Chem Pharm Fab Sterile eye gels containing medium chain triglycerides and process for their preparation
FR2737668B1 (en) * 1995-08-08 1997-10-31 Rocher Yves Biolog Vegetale BALLS BASED ON LIPOPHILIC SUBSTANCES, THEIR MANUFACTURING METHOD AND THEIR APPLICATIONS
JPH09268118A (en) * 1996-04-01 1997-10-14 Kao Corp Skin color-improving beautifier
DE19738247C2 (en) * 1997-09-02 2000-02-17 Goldwell Gmbh Hair care products
DE19952790A1 (en) * 1999-11-03 2001-05-17 Cognis Deutschland Gmbh Process for the production of fat granules
ITMI20012366A1 (en) * 2001-11-09 2003-05-09 Farmatron Ltd THERAPEUTIC SYSTEMS STABILIZED WITH IMMEDIATE RELEASE AND / OR MODIFIED FOR THE ORAL ADMINISTRATION OF ACTIVE AND / OR EXCIPIENT PRINCIPLES AND / OR WINGS
AU2003223005A1 (en) 2002-05-06 2003-11-17 Vectura Limited Application device for topical administration of pharmaceutical agents
US8980235B2 (en) * 2003-09-30 2015-03-17 Arch Chemicals, Inc. Coated metal pyrithione particles for treatment of microorganisms
US9861605B2 (en) 2011-10-24 2018-01-09 Stable Solutions Llc Enriched injectable emulsion containing selected fatty acid triglycerides
FR3075635B1 (en) * 2017-12-22 2019-12-06 Lvmh Recherche PROCESS FOR THE PREPARATION OF ANHYDROUS SPHEROIDS BY CRYOGENIA
KR102446371B1 (en) * 2019-06-11 2022-09-22 대봉엘에스 주식회사 Lipid composition and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB543309A (en) * 1940-12-04 1942-02-19 John David Evans Improvements in or relating to drugs
DE2309202A1 (en) * 1973-02-21 1974-08-29 Schering Ag MEDICINAL FORMS WITH MICRO-ENCAPSULATED MEDICINAL ACTIVE
DE2725924C3 (en) * 1977-06-08 1980-11-06 Hobeg Hochtemperaturreaktor-Brennelement Gmbh, 6450 Hanau Process for the production of spherical particles from low-melting organic substances

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU697767B2 (en) * 1995-03-17 1998-10-15 Gebro Broschek Gesellschaft M.B.H. Topically applicable pharmaceutical composition, process of manufacture, and use of the composition
US20080166413A1 (en) * 2000-06-26 2008-07-10 Pharmakodex Limited Topical pharmaceutical formulations and methods of treatment

Also Published As

Publication number Publication date
GR910300044T1 (en) 1991-11-15
JP2731008B2 (en) 1998-03-25
FI896321A0 (en) 1989-12-28
KR900009058A (en) 1990-07-02
DE376852T1 (en) 1991-07-04
PT92747A (en) 1990-06-29
NZ231982A (en) 1991-03-26
EP0376852A1 (en) 1990-07-04
LU87416A1 (en) 1990-07-10
DE68907335T2 (en) 1994-01-13
NO895307D0 (en) 1989-12-28
EP0376852B1 (en) 1993-06-23
ZA899961B (en) 1990-10-31
JPH02300116A (en) 1990-12-12
DK669789D0 (en) 1989-12-28
NO895307L (en) 1990-07-02
ES2034951T3 (en) 1994-10-16
AU617570B2 (en) 1991-11-28
ATE90869T1 (en) 1993-07-15
ES2034951T1 (en) 1993-04-16
DK669789A (en) 1990-06-30
CA2006834A1 (en) 1990-06-29
DE68907335D1 (en) 1993-07-29

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