AU472375B2 - Dialkylaminoalkyl esters of arylaliphatic acids and acid addition salts thereof - Google Patents

Dialkylaminoalkyl esters of arylaliphatic acids and acid addition salts thereof

Info

Publication number
AU472375B2
AU472375B2 AU56903/73A AU5690373A AU472375B2 AU 472375 B2 AU472375 B2 AU 472375B2 AU 56903/73 A AU56903/73 A AU 56903/73A AU 5690373 A AU5690373 A AU 5690373A AU 472375 B2 AU472375 B2 AU 472375B2
Authority
AU
Australia
Prior art keywords
acid addition
addition salts
dialkylaminoalkyl esters
arylaliphatic acids
arylaliphatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU56903/73A
Other languages
English (en)
Other versions
AU5690373A (en
Inventor
Marx Michael
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of AU5690373A publication Critical patent/AU5690373A/en
Application granted granted Critical
Publication of AU472375B2 publication Critical patent/AU472375B2/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/06Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
    • C07D233/08Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms
    • C07D233/12Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D233/14Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU56903/73A 1972-06-27 1973-06-14 Dialkylaminoalkyl esters of arylaliphatic acids and acid addition salts thereof Expired AU472375B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26664072A 1972-06-27 1972-06-27
USUS266,640 1972-06-27

Publications (2)

Publication Number Publication Date
AU5690373A AU5690373A (en) 1974-12-19
AU472375B2 true AU472375B2 (en) 1976-05-20

Family

ID=23015387

Family Applications (1)

Application Number Title Priority Date Filing Date
AU56903/73A Expired AU472375B2 (en) 1972-06-27 1973-06-14 Dialkylaminoalkyl esters of arylaliphatic acids and acid addition salts thereof

Country Status (13)

Country Link
JP (1) JPS5438097B2 (es)
AT (1) AT323145B (es)
AU (1) AU472375B2 (es)
BE (1) BE801440A (es)
CA (1) CA1012159A (es)
CH (1) CH581605A5 (es)
DE (1) DE2331665C2 (es)
ES (1) ES416311A1 (es)
FR (1) FR2190451B1 (es)
GB (1) GB1377316A (es)
IL (1) IL42472A (es)
NL (1) NL175910C (es)
ZA (1) ZA733992B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1508988A (en) * 1987-04-27 1988-10-27 Syntex Pharmaceuticals International Ltd. Omega-quaternary ammonium alkyl esters and thioesters of acidic nonsteroidal antiinflammatory drugs
KR101366296B1 (ko) * 2012-03-07 2014-02-21 주식회사 포스코 내화재 축조 방법
JP6290947B2 (ja) * 2016-02-05 2018-03-07 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚透過率を有するアリール−及びヘテロアリールプロピオン酸の正荷電水溶性プロドラッグ

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1406509A (fr) * 1963-05-02 1965-07-23 Parke Davis & Co Nouveaux composés naphtaléniques et procédé pour leur préparation
ZA701191B (en) * 1969-03-24 1971-09-29 Syntex Corp 2-(6-substituted-2'-naphthyl)acetic acid esters and process for producing same

Also Published As

Publication number Publication date
DE2331665A1 (de) 1974-01-17
FR2190451B1 (es) 1976-12-31
CA1012159A (en) 1977-06-14
NL175910C (nl) 1985-01-16
JPS504053A (es) 1975-01-16
IL42472A0 (en) 1973-08-29
AT323145B (de) 1975-06-25
CH581605A5 (es) 1976-11-15
JPS5438097B2 (es) 1979-11-19
IL42472A (en) 1977-01-31
NL175910B (nl) 1984-08-16
NL7308876A (es) 1974-01-02
ES416311A1 (es) 1976-05-16
AU5690373A (en) 1974-12-19
DE2331665C2 (de) 1983-04-21
ZA733992B (en) 1975-01-29
FR2190451A1 (es) 1974-02-01
BE801440A (fr) 1973-12-26
GB1377316A (en) 1974-12-11

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