AU4637799A - Azabicycle-substituted phenylindole derivatives as ligands for 5-ht2a receptors - Google Patents

Azabicycle-substituted phenylindole derivatives as ligands for 5-ht2a receptors

Info

Publication number
AU4637799A
AU4637799A AU46377/99A AU4637799A AU4637799A AU 4637799 A AU4637799 A AU 4637799A AU 46377/99 A AU46377/99 A AU 46377/99A AU 4637799 A AU4637799 A AU 4637799A AU 4637799 A AU4637799 A AU 4637799A
Authority
AU
Australia
Prior art keywords
azabicycle
ligands
substituted
ht2a receptors
phenylindole derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU46377/99A
Inventor
James Michael Crawforth
Simon Charles Goodacre
Kevin John Merchant
Michael Rowley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon Pharma UK Ltd
Original Assignee
Merck Sharp and Dohme Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp and Dohme Ltd filed Critical Merck Sharp and Dohme Ltd
Publication of AU4637799A publication Critical patent/AU4637799A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU46377/99A 1998-07-15 1999-07-07 Azabicycle-substituted phenylindole derivatives as ligands for 5-ht2a receptors Abandoned AU4637799A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9815317 1998-07-15
GBGB9815317.4A GB9815317D0 (en) 1998-07-15 1998-07-15 Therapeutic agents
PCT/GB1999/002177 WO2000004017A1 (en) 1998-07-15 1999-07-07 Azabicycle-substituted phenylindole derivatives as ligands for 5-ht2a receptors

Publications (1)

Publication Number Publication Date
AU4637799A true AU4637799A (en) 2000-02-07

Family

ID=10835531

Family Applications (1)

Application Number Title Priority Date Filing Date
AU46377/99A Abandoned AU4637799A (en) 1998-07-15 1999-07-07 Azabicycle-substituted phenylindole derivatives as ligands for 5-ht2a receptors

Country Status (3)

Country Link
AU (1) AU4637799A (en)
GB (1) GB9815317D0 (en)
WO (1) WO2000004017A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ510287A (en) 1998-11-27 2003-05-30 Neurosearch As 8-azabicyclo[3.2.1]oct-2-ene and -octane derivatives useful as cholinergic ligands at the nicotinic acetyl choline receptor
GB9919843D0 (en) * 1999-08-20 1999-10-27 Smithkline Beecham Plc Novel compounds
US6872834B2 (en) 2000-03-31 2005-03-29 Ortho-Mcneil Pharmaceutical, Inc. Phenyl-substituted indoles and indazoles
TW589312B (en) * 2001-05-25 2004-06-01 Wyeth Corp Aryl-8-azabicyclo[3.2.1]octanes for the treatment of depression

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK158590D0 (en) * 1990-07-02 1990-07-02 Lundbeck & Co As H indole derivatives
FR2735129B1 (en) * 1995-06-07 1997-07-11 Adir NOVEL INDOLE, INDAZOLE AND BENZISOXAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
GB9815317D0 (en) 1998-09-16
WO2000004017A1 (en) 2000-01-27

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase