AU4605285A - Prolonged storage of red blood cells - Google Patents

Prolonged storage of red blood cells

Info

Publication number
AU4605285A
AU4605285A AU46052/85A AU4605285A AU4605285A AU 4605285 A AU4605285 A AU 4605285A AU 46052/85 A AU46052/85 A AU 46052/85A AU 4605285 A AU4605285 A AU 4605285A AU 4605285 A AU4605285 A AU 4605285A
Authority
AU
Australia
Prior art keywords
blood cells
red blood
prolonged storage
suspension medium
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU46052/85A
Other versions
AU569958B2 (en
Inventor
Marne Hornblower
Harold T. Meryman
Ralph Syring
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
American National Red Cross
Original Assignee
American National Red Cross
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American National Red Cross filed Critical American National Red Cross
Publication of AU4605285A publication Critical patent/AU4605285A/en
Application granted granted Critical
Publication of AU569958B2 publication Critical patent/AU569958B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/18—Erythrocytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Organic Insulating Materials (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • External Artificial Organs (AREA)

Abstract

The present invention discloses a hypotonic suspension medium and a method for prolonged storage of red blood cells at about 4 DEG C. The suspension medium comprises about 80-150 mM glucose, 30-80 mM mannitol, 6-90 mM potassium citrate, 1-5 mM adenine and 10-200 mM ammonium chloride or acetate in an aqueous solution having a pH of about 6.8 to 7.2 and an osmolarity of about 180-220 milli-osmolar. The suspension medium and the method of the present invention allow viable storage of red blood cells at about 4 DEG C. up to 125 days or more.
AU46052/85A 1984-07-19 1985-06-21 Prolonged storage of red blood cells Expired AU569958B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/632,242 US4585735A (en) 1984-07-19 1984-07-19 Prolonged storage of red blood cells
US632242 1984-07-19

Publications (2)

Publication Number Publication Date
AU4605285A true AU4605285A (en) 1986-02-25
AU569958B2 AU569958B2 (en) 1988-02-25

Family

ID=24534708

Family Applications (1)

Application Number Title Priority Date Filing Date
AU46052/85A Expired AU569958B2 (en) 1984-07-19 1985-06-21 Prolonged storage of red blood cells

Country Status (12)

Country Link
US (1) US4585735A (en)
EP (1) EP0187816B1 (en)
JP (1) JPS61502750A (en)
AT (1) ATE66814T1 (en)
AU (1) AU569958B2 (en)
CA (1) CA1254838A (en)
DE (1) DE3584010D1 (en)
DK (1) DK168079B1 (en)
FI (1) FI84135C (en)
IL (1) IL75707A (en)
NO (1) NO167075C (en)
WO (1) WO1986000809A1 (en)

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JPH0687062B2 (en) * 1985-05-10 1994-11-02 株式会社京都医科学研究所 How to prevent glycolysis in blood
US4675185A (en) * 1985-12-06 1987-06-23 Baxter Travenol Laboratories, Inc. Solution for stabilizing red blood cells during storage
JPS6360931A (en) * 1986-08-29 1988-03-17 Noboru Sato Solution for preserving blood or blood preparation and preservation of blood or blood preparation using said solution
IL90188A0 (en) * 1988-05-18 1989-12-15 Cryopharm Corp Process and medium for the lyophilization of erythrocytes
US5045446A (en) * 1988-08-26 1991-09-03 Cryopharm Corporation Lyophilization of cells
US4874690A (en) * 1988-08-26 1989-10-17 Cryopharm Corporation Lyophilization of red blood cells
IL95912A (en) * 1989-10-06 1998-08-16 American Nat Red Cross Method for prolonging the shelf life or red blood cells
CA2067134C (en) * 1989-10-06 2001-02-13 Harold T. Meryman Procedure for storing red cells with prolonged maintenance of cellular concentrations of atp and 2,3 dpg
DE3938907C2 (en) * 1989-11-24 1999-11-04 Dade Behring Marburg Gmbh Means for storing and suspending cells, in particular erythrocytes
US5147776A (en) * 1990-02-26 1992-09-15 University Of Iowa Research Foundation Use of 2,5-anhydromannitol for control of pH during blood storage
US5545516A (en) * 1990-05-01 1996-08-13 The American National Red Cross Inactivation of extracellular enveloped viruses in blood and blood components by phenthiazin-5-ium dyes plus light
EP0509083B1 (en) * 1990-11-07 1997-07-16 Baxter International Inc. Red blood cell storage solution
CA2071835A1 (en) * 1990-11-07 1992-05-08 Gerald A. Grode Blood platelet storage medium
WO1996014741A2 (en) * 1994-11-14 1996-05-23 Pall Corporation Long-term blood component storage system and method
US5601972A (en) * 1995-03-24 1997-02-11 Organ, Inc. Long term storage of red cells in unfrozen solution
US20040053208A1 (en) * 1995-08-29 2004-03-18 V. I. TECHNOLOGIES, Inc. Methods to selectively inactivate parasites in biological compositions
US5736313A (en) * 1995-10-20 1998-04-07 The United States Of America As Represented By The Secretary Of The Navy Method of lyophilizing platelets by incubation with high carbohydrate concentrations and supercooling prior to freezing
EP0973383A4 (en) * 1997-01-21 2001-08-22 American Nat Red Cross Intracellular and extracellular decontamination of whole blood and blood components by amphiphilic phenothiazin-5-ium dyes plus light
US5789151A (en) * 1997-05-15 1998-08-04 The Regents Of The University Of California Prolonged cold storage of red blood cells by oxygen removal and additive usage
US20030215784A1 (en) * 1998-07-21 2003-11-20 Dumont Larry Joe Method and apparatus for inactivation of biological contaminants using photosensitizers
US7498156B2 (en) * 1998-07-21 2009-03-03 Caridianbct Biotechnologies, Llc Use of visible light at wavelengths of 500 to 550 nm to reduce the number of pathogens in blood and blood components
US7049110B2 (en) * 1998-07-21 2006-05-23 Gambro, Inc. Inactivation of West Nile virus and malaria using photosensitizers
US20070099170A1 (en) * 1998-07-21 2007-05-03 Navigant Biotechnologies, Inc. Method for treatment and storage of blood and blood products using endogenous alloxazines and acetate
US6267925B1 (en) 1998-12-07 2001-07-31 Haemonetics Corporation Method for cryopreservation and recovery of red blood cells
US7220747B2 (en) 1999-07-20 2007-05-22 Gambro, Inc. Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer
EP1255439A4 (en) * 2000-02-10 2007-01-03 Univ California Therapeutic platelets and methods
US6770478B2 (en) 2000-02-10 2004-08-03 The Regents Of The University Of California Erythrocytic cells and method for preserving cells
US7985588B2 (en) * 2000-06-02 2011-07-26 Caridianbct Biotechnologies, Llc Induction of and maintenance of nucleic acid damage in pathogens using riboflavin and light
US7648699B2 (en) * 2000-06-02 2010-01-19 Caridianbct Biotechnologies, Llc Preventing transfusion related complications in a recipient of a blood transfusion
TW590780B (en) * 2000-06-02 2004-06-11 Gambro Inc Additive solutions containing riboflavin
US6548241B1 (en) * 2000-11-28 2003-04-15 Gambro, Inc. Storage solution containing photosensitizer for inactivation of biological contaminants
US20020131958A1 (en) * 2001-01-22 2002-09-19 John Chapman Method for purifying a biological composition
US7183045B2 (en) * 2002-04-24 2007-02-27 Gambro Inc. Removal of adenine during a pathogen reduction process in whole blood or red blood cell by dilution
US8828226B2 (en) 2003-03-01 2014-09-09 The Trustees Of Boston University System for assessing the efficacy of stored red blood cells using microvascular networks
WO2004112477A1 (en) * 2003-06-20 2004-12-29 Pall Corporation Processing of platelet-containing biological fluids
US9314014B2 (en) 2004-02-18 2016-04-19 University Of Maryland, Baltimore Compositions and methods for the storage of red blood cells
WO2008089337A1 (en) * 2007-01-19 2008-07-24 The Regents Of The University Of Michigan Compositions and methods for preserving red blood cells
JP2010535235A (en) * 2007-08-01 2010-11-18 カリディアンビーシーティ バイオテクノロジーズ，エルエルシー Pathogenic inactivation of whole blood
US8835104B2 (en) * 2007-12-20 2014-09-16 Fenwal, Inc. Medium and methods for the storage of platelets
US8968992B2 (en) * 2008-03-21 2015-03-03 Fenwal, Inc. Red blood cell storage medium for extended storage
US8871434B2 (en) * 2008-03-21 2014-10-28 Fenwal, Inc. Red blood cell storage medium for extended storage
US9199016B2 (en) 2009-10-12 2015-12-01 New Health Sciences, Inc. System for extended storage of red blood cells and methods of use
AU2010306920A1 (en) 2009-10-12 2012-05-31 New Health Sciences, Inc. Oxygen depletion devices and methods for removing oxygen from red blood cells
US11284616B2 (en) 2010-05-05 2022-03-29 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
WO2011046841A1 (en) 2009-10-12 2011-04-21 New Health Sciences, Inc. Blood storage bag system and depletion devices with oxygen and carbon dioxide depletion capabilities
US20130203042A1 (en) * 2009-10-23 2013-08-08 Fenwal, Inc. Methods and systems for processing biological fluids
US11864553B2 (en) 2009-10-23 2024-01-09 Fenwal, Inc. Methods and systems for providing red blood cell products with reduced plasma
CN102869364A (en) 2010-02-16 2013-01-09 维亚塞尔有限责任公司 Arginine-containing compositions and methods for treating red blood cells
WO2011103177A1 (en) * 2010-02-16 2011-08-25 Viacell, Llc Nucleoside-containing compositions and methods for treating red blood cells
EP2608816B1 (en) 2010-08-25 2023-07-05 Hemanext Inc. Method for enhancing red blood cell quality and survival during storage
PT3539381T (en) 2010-11-05 2023-09-26 Hemanext Inc Irradiation of red blood cells and anaerobic storage
US9067004B2 (en) 2011-03-28 2015-06-30 New Health Sciences, Inc. Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly
EP3662750A1 (en) 2011-04-07 2020-06-10 Fenwal, Inc. Automated methods and systems for providing platelet concentrates with reduced residual plasma volumes and storage media for such platelet concentrates
AU2012294269B2 (en) 2011-08-10 2016-11-24 Hemanext Inc. Integrated leukocyte, oxygen and/or CO2 depletion, and plasma separation filter device
EP2874641A4 (en) 2012-07-23 2016-10-12 Oneday Biotech And Pharma Ltd Glutathione-elevating compositions and uses thereof
US9877476B2 (en) 2013-02-28 2018-01-30 New Health Sciences, Inc. Gas depletion and gas addition devices for blood treatment
MX2017011595A (en) 2015-03-10 2018-06-15 New Health Sciences Inc Oxygen reduction disposable kits, devices and methods of use thereof.
JP7175611B2 (en) 2015-04-23 2022-11-21 ヘマネクスト インコーポレイテッド Anaerobic blood storage container
BR112017024091B1 (en) 2015-05-18 2022-09-20 Hemanext Inc METHOD TO REDUCE CYTOKINES IN A STORED WHOLE BLOOD PRODUCT, STORED WHOLE BLOOD COMPOSITION AND USE OF A STORED WHOLE BLOOD PRODUCT
JP7148499B2 (en) 2016-05-27 2022-10-05 ヘマネクスト インコーポレイテッド Anaerobic blood storage and pathogen inactivation methods
CN110907642A (en) * 2019-12-02 2020-03-24 青岛农业大学 Kit and method for rapidly detecting canine parvovirus antigen and canine parvovirus antibody

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DE2532183C3 (en) * 1975-07-18 1982-03-04 Behringwerke Ag, 3550 Marburg Polyionic isotonic saline solution for the preservation of erythrocytes or for the perfusion and preservation of organs intended for transplantation
JPS56139419A (en) * 1980-03-31 1981-10-30 Kuraray Co Ltd Erythrocytic preservative and erythrocytic pharmaceutical for preservation
FR2542617B2 (en) * 1982-07-09 1986-06-06 Rgl Transfusion Sanguine Centr PROTECTIVE SOLUTION FOR THE PRESERVATION OF FUNCTIONAL CELLS

Also Published As

Publication number Publication date
JPS61502750A (en) 1986-11-27
EP0187816A1 (en) 1986-07-23
ATE66814T1 (en) 1991-09-15
EP0187816A4 (en) 1988-04-06
FI84135C (en) 1991-10-25
IL75707A0 (en) 1985-11-29
FI861137A0 (en) 1986-03-18
FI861137A (en) 1986-03-18
NO167075B (en) 1991-06-24
EP0187816B1 (en) 1991-09-04
FI84135B (en) 1991-07-15
JPH0572888B2 (en) 1993-10-13
NO167075C (en) 1991-10-02
NO860913L (en) 1986-03-11
IL75707A (en) 1989-02-28
CA1254838A (en) 1989-05-30
DK119986A (en) 1986-03-14
AU569958B2 (en) 1988-02-25
DK119986D0 (en) 1986-03-14
DE3584010D1 (en) 1991-10-10
DK168079B1 (en) 1994-02-07
US4585735A (en) 1986-04-29
WO1986000809A1 (en) 1986-02-13

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