AU4547199A - Tissue connector apparatus and methods - Google Patents
Tissue connector apparatus and methods Download PDFInfo
- Publication number
- AU4547199A AU4547199A AU45471/99A AU4547199A AU4547199A AU 4547199 A AU4547199 A AU 4547199A AU 45471/99 A AU45471/99 A AU 45471/99A AU 4547199 A AU4547199 A AU 4547199A AU 4547199 A AU4547199 A AU 4547199A
- Authority
- AU
- Australia
- Prior art keywords
- clip
- connector assembly
- tissue connector
- needle
- tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000000034 method Methods 0.000 title claims abstract description 60
- 230000000452 restraining effect Effects 0.000 claims abstract description 49
- 230000007246 mechanism Effects 0.000 claims description 52
- 239000000463 material Substances 0.000 claims description 34
- 230000006835 compression Effects 0.000 claims description 18
- 238000007906 compression Methods 0.000 claims description 18
- 238000003780 insertion Methods 0.000 claims description 16
- 230000037431 insertion Effects 0.000 claims description 16
- 230000008878 coupling Effects 0.000 claims description 11
- 238000010168 coupling process Methods 0.000 claims description 11
- 238000005859 coupling reaction Methods 0.000 claims description 11
- 230000007704 transition Effects 0.000 claims description 10
- 239000012781 shape memory material Substances 0.000 claims description 4
- 210000001519 tissue Anatomy 0.000 description 190
- 210000001367 artery Anatomy 0.000 description 72
- 238000000429 assembly Methods 0.000 description 43
- 230000000712 assembly Effects 0.000 description 43
- 230000003872 anastomosis Effects 0.000 description 28
- 238000001356 surgical procedure Methods 0.000 description 12
- 230000000149 penetrating effect Effects 0.000 description 11
- 238000002324 minimally invasive surgery Methods 0.000 description 8
- 229910001285 shape-memory alloy Inorganic materials 0.000 description 8
- 230000017531 blood circulation Effects 0.000 description 7
- 239000003356 suture material Substances 0.000 description 7
- 238000007631 vascular surgery Methods 0.000 description 7
- 238000003466 welding Methods 0.000 description 7
- 210000000683 abdominal cavity Anatomy 0.000 description 6
- 229910001000 nickel titanium Inorganic materials 0.000 description 6
- 210000000574 retroperitoneal space Anatomy 0.000 description 6
- 230000002792 vascular Effects 0.000 description 6
- 238000004026 adhesive bonding Methods 0.000 description 5
- 210000000038 chest Anatomy 0.000 description 5
- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical compound [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 description 5
- 238000002355 open surgical procedure Methods 0.000 description 5
- 241001631457 Cannula Species 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 239000010935 stainless steel Substances 0.000 description 4
- 229910001220 stainless steel Inorganic materials 0.000 description 4
- 230000009466 transformation Effects 0.000 description 4
- 210000000709 aorta Anatomy 0.000 description 3
- 210000004351 coronary vessel Anatomy 0.000 description 3
- 229910000734 martensite Inorganic materials 0.000 description 3
- 230000013011 mating Effects 0.000 description 3
- 229910001092 metal group alloy Inorganic materials 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000035515 penetration Effects 0.000 description 3
- 230000002093 peripheral effect Effects 0.000 description 3
- 210000003462 vein Anatomy 0.000 description 3
- 229920004934 Dacron® Polymers 0.000 description 2
- 210000001015 abdomen Anatomy 0.000 description 2
- 230000003187 abdominal effect Effects 0.000 description 2
- 230000008321 arterial blood flow Effects 0.000 description 2
- 238000010009 beating Methods 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 238000007675 cardiac surgery Methods 0.000 description 2
- 238000013130 cardiovascular surgery Methods 0.000 description 2
- 238000002788 crimping Methods 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 210000001349 mammary artery Anatomy 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 230000010410 reperfusion Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 239000003381 stabilizer Substances 0.000 description 2
- 206010060954 Abdominal Hernia Diseases 0.000 description 1
- 229920000544 Gore-Tex Polymers 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 229910001260 Pt alloy Inorganic materials 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- HZEWFHLRYVTOIW-UHFFFAOYSA-N [Ti].[Ni] Chemical compound [Ti].[Ni] HZEWFHLRYVTOIW-UHFFFAOYSA-N 0.000 description 1
- 210000003815 abdominal wall Anatomy 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 230000000151 anti-reflux effect Effects 0.000 description 1
- 230000003881 arterial anastomosis Effects 0.000 description 1
- 229910001566 austenite Inorganic materials 0.000 description 1
- 230000006399 behavior Effects 0.000 description 1
- 238000013131 cardiovascular procedure Methods 0.000 description 1
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- 238000006243 chemical reaction Methods 0.000 description 1
- 238000002192 cholecystectomy Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
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- 230000007812 deficiency Effects 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002674 endoscopic surgery Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000003238 esophagus Anatomy 0.000 description 1
- 229920000295 expanded polytetrafluoroethylene Polymers 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- NBVXSUQYWXRMNV-UHFFFAOYSA-N fluoromethane Chemical compound FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 210000004300 gastroepiploic artery Anatomy 0.000 description 1
- 210000005003 heart tissue Anatomy 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000002439 hemostatic effect Effects 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 238000007912 intraperitoneal administration Methods 0.000 description 1
- 238000005304 joining Methods 0.000 description 1
- 238000002357 laparoscopic surgery Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000012978 minimally invasive surgical procedure Methods 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 210000002321 radial artery Anatomy 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 210000003752 saphenous vein Anatomy 0.000 description 1
- 238000005476 soldering Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 210000000779 thoracic wall Anatomy 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
- 231100000827 tissue damage Toxicity 0.000 description 1
- 230000019432 tissue death Effects 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/08—Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound
- A61B17/083—Clips, e.g. resilient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
- A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
- A61B17/062—Needle manipulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
- A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
- A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
- A61B17/06004—Means for attaching suture to needle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00831—Material properties
- A61B2017/00867—Material properties shape memory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
- A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
- A61B2017/06057—Double-armed sutures, i.e. sutures having a needle attached to each end
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
- A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
- A61B17/06066—Needles, e.g. needle tip configurations
- A61B2017/06076—Needles, e.g. needle tip configurations helically or spirally coiled
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/11—Surgical instruments, devices or methods for performing anastomosis; Buttons for anastomosis
- A61B2017/1135—End-to-side connections, e.g. T- or Y-connections
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/3006—Properties of materials and coating materials
- A61F2002/30092—Properties of materials and coating materials using shape memory or superelastic materials, e.g. nitinol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0014—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
- A61F2210/0019—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol operated at only one temperature whilst inside or touching the human body, e.g. constrained in a non-operative shape during surgery, another temperature only occurring before the operation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- Prostheses (AREA)
- Woven Fabrics (AREA)
- Tents Or Canopies (AREA)
- Replacement Of Web Rolls (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/090,305 US6641593B1 (en) | 1998-06-03 | 1998-06-03 | Tissue connector apparatus and methods |
| US09090305 | 1998-06-03 | ||
| US09259705 | 1999-03-01 | ||
| US09/259,705 US6514265B2 (en) | 1999-03-01 | 1999-03-01 | Tissue connector apparatus with cable release |
| PCT/US1999/012563 WO1999062409A1 (en) | 1998-06-03 | 1999-06-03 | Tissue connector apparatus and methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU4547199A true AU4547199A (en) | 1999-12-20 |
Family
ID=26782136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU45471/99A Abandoned AU4547199A (en) | 1998-06-03 | 1999-06-03 | Tissue connector apparatus and methods |
Country Status (7)
| Country | Link |
|---|---|
| EP (2) | EP1997441B1 (https=) |
| JP (1) | JP4102024B2 (https=) |
| AT (2) | ATE420598T1 (https=) |
| AU (1) | AU4547199A (https=) |
| CA (1) | CA2333999C (https=) |
| DE (1) | DE69940311D1 (https=) |
| WO (1) | WO1999062409A1 (https=) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6607541B1 (en) | 1998-06-03 | 2003-08-19 | Coalescent Surgical, Inc. | Tissue connector apparatus and methods |
| US6206913B1 (en) | 1998-08-12 | 2001-03-27 | Vascular Innovations, Inc. | Method and system for attaching a graft to a blood vessel |
| US6461320B1 (en) | 1998-08-12 | 2002-10-08 | Cardica, Inc. | Method and system for attaching a graft to a blood vessel |
| US6428550B1 (en) | 1999-05-18 | 2002-08-06 | Cardica, Inc. | Sutureless closure and deployment system for connecting blood vessels |
| AU5150600A (en) | 1999-05-18 | 2000-12-05 | Vascular Innovations, Inc. | Tissue punch |
| US7048751B2 (en) | 2001-12-06 | 2006-05-23 | Cardica, Inc. | Implantable medical device such as an anastomosis device |
| US6673088B1 (en) | 1999-05-18 | 2004-01-06 | Cardica, Inc. | Tissue punch |
| US8529583B1 (en) | 1999-09-03 | 2013-09-10 | Medtronic, Inc. | Surgical clip removal apparatus |
| US6926730B1 (en) | 2000-10-10 | 2005-08-09 | Medtronic, Inc. | Minimally invasive valve repair procedure and apparatus |
| AU2001245504A1 (en) | 2000-03-07 | 2002-02-25 | Metacardia, Inc. | Everting staple devices and methods |
| US6918917B1 (en) | 2000-10-10 | 2005-07-19 | Medtronic, Inc. | Minimally invasive annuloplasty procedure and apparatus |
| US6776785B1 (en) | 2000-10-12 | 2004-08-17 | Cardica, Inc. | Implantable superelastic anastomosis device |
| US20020173803A1 (en) | 2001-05-01 | 2002-11-21 | Stephen Ainsworth | Self-closing surgical clip for tissue |
| US10098640B2 (en) | 2001-12-04 | 2018-10-16 | Atricure, Inc. | Left atrial appendage devices and methods |
| US7335216B2 (en) | 2002-01-22 | 2008-02-26 | Cardica, Inc. | Tool for creating an opening in tissue |
| US7029482B1 (en) | 2002-01-22 | 2006-04-18 | Cardica, Inc. | Integrated anastomosis system |
| US7223274B2 (en) | 2002-01-23 | 2007-05-29 | Cardica, Inc. | Method of performing anastomosis |
| US7497857B2 (en) | 2003-04-29 | 2009-03-03 | Medtronic, Inc. | Endocardial dispersive electrode for use with a monopolar RF ablation pen |
| US7585306B2 (en) | 2003-12-24 | 2009-09-08 | Maquet Cardiovascular Llc | Anastomosis device, tools and methods of using |
| US7645285B2 (en) | 2004-05-26 | 2010-01-12 | Idx Medical, Ltd | Apparatus and methods for occluding a hollow anatomical structure |
| US8409219B2 (en) | 2004-06-18 | 2013-04-02 | Medtronic, Inc. | Method and system for placement of electrical lead inside heart |
| US8876820B2 (en) | 2004-10-20 | 2014-11-04 | Atricure, Inc. | Surgical clamp |
| WO2007009099A2 (en) | 2005-07-14 | 2007-01-18 | Idx Medical Ltd. | Apparatus and methods for occluding a hollow anatomical structure |
| US20080243141A1 (en) | 2007-04-02 | 2008-10-02 | Salvatore Privitera | Surgical instrument with separate tool head and method of use |
| WO2010011661A1 (en) | 2008-07-21 | 2010-01-28 | Atricure, Inc. | Apparatus and methods for occluding an anatomical structure |
| US9393023B2 (en) | 2009-01-13 | 2016-07-19 | Atricure, Inc. | Apparatus and methods for deploying a clip to occlude an anatomical structure |
| US9737687B2 (en) | 2010-09-22 | 2017-08-22 | The Johns Hopkins University | Cable-driven morphable manipulator |
| US9017349B2 (en) | 2010-10-27 | 2015-04-28 | Atricure, Inc. | Appendage clamp deployment assist device |
| US9066741B2 (en) | 2010-11-01 | 2015-06-30 | Atricure, Inc. | Robotic toolkit |
| US8636754B2 (en) | 2010-11-11 | 2014-01-28 | Atricure, Inc. | Clip applicator |
| US9265486B2 (en) | 2011-08-15 | 2016-02-23 | Atricure, Inc. | Surgical device |
| US9282973B2 (en) | 2012-01-20 | 2016-03-15 | Atricure, Inc. | Clip deployment tool and associated methods |
| US9901351B2 (en) | 2012-11-21 | 2018-02-27 | Atricure, Inc. | Occlusion clip |
| BR112016011572B1 (pt) | 2013-11-21 | 2022-08-16 | Atricure, Inc | Grampo de oclusão |
| JP6463850B2 (ja) | 2014-12-12 | 2019-02-06 | アトリキュア インクＡｔｒｉｃｕｒｅ Ｉｎｃ． | 閉塞クリップ |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3462802A (en) * | 1968-04-15 | 1969-08-26 | Dennison Mfg Co | Connector for holding articles together |
| US4345601A (en) * | 1980-04-07 | 1982-08-24 | Mamoru Fukuda | Continuous suturing device |
| US4899744A (en) * | 1988-12-15 | 1990-02-13 | Tatsuo Fujitsuka | Apparatus for anastomosing digestive tract |
| US5002563A (en) * | 1990-02-22 | 1991-03-26 | Raychem Corporation | Sutures utilizing shape memory alloys |
| US5282811A (en) * | 1992-04-16 | 1994-02-01 | Cook Pacemaker Corporation | Two part surgical ligating clip, applicator and method of use |
| US5810851A (en) * | 1996-03-05 | 1998-09-22 | Yoon; Inbae | Suture spring device |
| US6613059B2 (en) | 1999-03-01 | 2003-09-02 | Coalescent Surgical, Inc. | Tissue connector apparatus and methods |
| US6607541B1 (en) | 1998-06-03 | 2003-08-19 | Coalescent Surgical, Inc. | Tissue connector apparatus and methods |
-
1999
- 1999-06-03 AT AT99928396T patent/ATE420598T1/de not_active IP Right Cessation
- 1999-06-03 EP EP08016505A patent/EP1997441B1/en not_active Expired - Lifetime
- 1999-06-03 JP JP2000551672A patent/JP4102024B2/ja not_active Expired - Lifetime
- 1999-06-03 EP EP99928396A patent/EP1083832B1/en not_active Expired - Lifetime
- 1999-06-03 DE DE69940311T patent/DE69940311D1/de not_active Expired - Lifetime
- 1999-06-03 CA CA002333999A patent/CA2333999C/en not_active Expired - Lifetime
- 1999-06-03 WO PCT/US1999/012563 patent/WO1999062409A1/en not_active Ceased
- 1999-06-03 AT AT08016505T patent/ATE516758T1/de not_active IP Right Cessation
- 1999-06-03 AU AU45471/99A patent/AU4547199A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ATE420598T1 (de) | 2009-01-15 |
| JP2002516694A (ja) | 2002-06-11 |
| EP1083832A1 (en) | 2001-03-21 |
| CA2333999C (en) | 2009-11-03 |
| CA2333999A1 (en) | 1999-12-09 |
| ATE516758T1 (de) | 2011-08-15 |
| DE69940311D1 (de) | 2009-03-05 |
| WO1999062409A9 (en) | 2000-02-10 |
| EP1997441B1 (en) | 2011-07-20 |
| EP1083832B1 (en) | 2009-01-14 |
| EP1997441A1 (en) | 2008-12-03 |
| WO1999062409A1 (en) | 1999-12-09 |
| JP4102024B2 (ja) | 2008-06-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK5 | Application lapsed section 142(2)(e) - patent request and compl. specification not accepted |